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Conserved domains on  [gi|1059155856|ref|XP_017734291|]
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PREDICTED: solute carrier family 12 member 3 isoform X1 [Rhinopithecus bieti]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
59-948 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1424.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856  59 NTIDVVPAYEHYANSTQPGEPRKVRPTLADLHSFLKQEGRHLHALAFDSRPSHEMTDGLVEDEAGTSSEKNPEEPVRFGW 138
Cdd:TIGR00930   1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAGAVKFGW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 139 VKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGS 218
Cdd:TIGR00930  81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 219 IGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPI-VDPINDIRIIGVVSVTVLLAISLAGMEWESK------------- 284
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETVLDLLRENGSKImVDPINDIRIYGTVTVVVLLGISFAGMEWENKaqvlflvivllsi 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 285 -------------------------------------------------------------------DPAVAIPKGTLMA 297
Cdd:TIGR00930 241 lnifvgtiipafdkpakgffglgneifsenfipgipgpeggffslfgiffpsvtgilaganisgdlkDPQKAIPKGTLLA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 298 IFWTTISYLAISATIGSCVVRDASGVLNDTMTPgwgACEGLACgygwnFTECTQQhSCRYGLINYYQTMSMVSGFAPLIT 377
Cdd:TIGR00930 321 ILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC-----FSECAHN-TCSYGLMNNLQVMSLVSPFPPLIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 378 AGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLC 457
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLA 471
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 458 SYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQA 537
Cdd:TIGR00930 472 SYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQA 551
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 538 GSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLITNGHTK 617
Cdd:TIGR00930 552 LSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQT 631
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 618 WLNKRKIKAFYSDIIAEDLRKGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMRE 697
Cdd:TIGR00930 632 WLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSE 711
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 698 GLNVSkMMQAHINPVFDPAEDGKEASARGArpsvsgaldPEALVQEEQATTVFQSEQGKKTIDIYWLFDDGGLTLLIPYL 777
Cdd:TIGR00930 712 GLPIS-VLQVQEELENDCSEDSIELNDGKI---------STQPDMHLEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYL 781
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 778 LGRKKRWSKCKIRVFVGGQ-INRMDQERKAIISLLSKFRLGFHEVHILPDINQIPRAEHTKRFEDMIAPFRLNDGFKDEA 856
Cdd:TIGR00930 782 LTTKKVWKKCKIRIFVGAQkDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRLHKTEKDRE 861
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 857 TVN-EMRRDCPWKISDEEMRKNRVKSLRQVRLNEILLDYSRDAALVVITLPIGRKGECPSSLYMAWLETLSQDLrPPVIL 935
Cdd:TIGR00930 862 AKDpKMTWTKPWKITDAELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDL-PPVLL 940
                         970
                  ....*....|...
gi 1059155856 936 IRGNQENVLTFYC 948
Cdd:TIGR00930 941 VRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
59-948 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1424.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856  59 NTIDVVPAYEHYANSTQPGEPRKVRPTLADLHSFLKQEGRHLHALAFDSRPSHEMTDGLVEDEAGTSSEKNPEEPVRFGW 138
Cdd:TIGR00930   1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAGAVKFGW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 139 VKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGS 218
Cdd:TIGR00930  81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 219 IGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPI-VDPINDIRIIGVVSVTVLLAISLAGMEWESK------------- 284
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETVLDLLRENGSKImVDPINDIRIYGTVTVVVLLGISFAGMEWENKaqvlflvivllsi 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 285 -------------------------------------------------------------------DPAVAIPKGTLMA 297
Cdd:TIGR00930 241 lnifvgtiipafdkpakgffglgneifsenfipgipgpeggffslfgiffpsvtgilaganisgdlkDPQKAIPKGTLLA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 298 IFWTTISYLAISATIGSCVVRDASGVLNDTMTPgwgACEGLACgygwnFTECTQQhSCRYGLINYYQTMSMVSGFAPLIT 377
Cdd:TIGR00930 321 ILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC-----FSECAHN-TCSYGLMNNLQVMSLVSPFPPLIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 378 AGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLC 457
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLA 471
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 458 SYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQA 537
Cdd:TIGR00930 472 SYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQA 551
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 538 GSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLITNGHTK 617
Cdd:TIGR00930 552 LSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQT 631
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 618 WLNKRKIKAFYSDIIAEDLRKGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMRE 697
Cdd:TIGR00930 632 WLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSE 711
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 698 GLNVSkMMQAHINPVFDPAEDGKEASARGArpsvsgaldPEALVQEEQATTVFQSEQGKKTIDIYWLFDDGGLTLLIPYL 777
Cdd:TIGR00930 712 GLPIS-VLQVQEELENDCSEDSIELNDGKI---------STQPDMHLEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYL 781
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 778 LGRKKRWSKCKIRVFVGGQ-INRMDQERKAIISLLSKFRLGFHEVHILPDINQIPRAEHTKRFEDMIAPFRLNDGFKDEA 856
Cdd:TIGR00930 782 LTTKKVWKKCKIRIFVGAQkDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRLHKTEKDRE 861
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 857 TVN-EMRRDCPWKISDEEMRKNRVKSLRQVRLNEILLDYSRDAALVVITLPIGRKGECPSSLYMAWLETLSQDLrPPVIL 935
Cdd:TIGR00930 862 AKDpKMTWTKPWKITDAELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDL-PPVLL 940
                         970
                  ....*....|...
gi 1059155856 936 IRGNQENVLTFYC 948
Cdd:TIGR00930 941 VRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
574-948 2.35e-171

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 504.84  E-value: 2.35e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 574 RPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELqlITNGHTKWLNKRKIKAFYSDIIAEDLRKGVQILMQAAGLGRMK 653
Cdd:pfam03522   1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSE--LQKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLK 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 654 PNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQA----------HINPVFDPAEDGKEAS 723
Cdd:pfam03522  79 PNILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDqdteelglgdETNSSYAEQSSEEQST 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 724 ARG------------------------ARPSVSGALDPEALVQEE---------------QATTVFQSEQGKKTIDIYWL 764
Cdd:pfam03522 159 SNSkqdddksklskkdsnlslspdkstKNPSGKDSSKSDKLKKKSpsiilrtasnekeilNNITQFQKKQKKGTIDVWWL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 765 FDDGGLTLLIPYLLGRKKRWSKCKIRVFVGG-QINRMDQERKAIISLLSKFRLGFHEVHILPDINQIPRAEHTKRFEDMI 843
Cdd:pfam03522 239 YDDGGLTLLLPYILSTRSKWSDCKLRVFALGnRKDELEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETKKFFDELI 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 844 APFRLNDGFKDEATVnemrrdcpWKISDEEMRKNRVKSLRQVRLNEILLDYSRDAALVVITLPIGRKGECPSSLYMAWLE 923
Cdd:pfam03522 319 EPFRLHEDDKEEESA--------EKITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLE 390
                         410       420
                  ....*....|....*....|....*
gi 1059155856 924 TLSQDLrPPVILIRGNQENVLTFYC 948
Cdd:pfam03522 391 TLTKDL-PPFLLVRGNQTSVLTFYS 414
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
125-526 1.72e-20

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 95.35  E-value: 1.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 125 SSEKNPEEPVRFGWVKGVMIrCMLNIWGVILYLrLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNgKVKSGGTY 204
Cdd:COG0531     2 SRGESSELKRKLGLFDLVAL-GVGAIIGAGIFV-LPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASA-FPRAGGAY 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 205 FLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPIVDP----------INDIR-------IIGVVS 267
Cdd:COG0531    79 TYARRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVLIALvlillltllnLRGVKesakvnnILTVLK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 268 VTVLLAISLAGMEW-----------------------------------------ESKDPAVAIPKGTLMAIFWTTISYL 306
Cdd:COG0531   159 LLVLLLFIVVGLFAfdpanftpflpaggglsgvlaalalaffaftgfeaianlaeEAKNPKRNIPRAIILSLLIVGVLYI 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 307 AISATIGSCV----VRDASGVLNDTMTPGWGaceglacgygwnftectqqhscryglinyyqtmsmvSGFAPLITAGIFG 382
Cdd:COG0531   239 LVSLALTGVVpydeLAASGAPLADAAEAVFG------------------------------------PWGAILIALGALL 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 383 ATLSSALACLVSAAKVFQCLCEDQLYPliGFFGKGYGKNKEPVRGYLLAY--AIAVAFIIIAELNTIAPIISNFFLCSYA 460
Cdd:COG0531   283 SLLGALNASILGASRLLYAMARDGLLP--KVFAKVHPRFGTPVNAILLTGviALLLLLLGAASFTALASLASVGVLLAYL 360
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1059155856 461 LINFSCFHASITNSPGWRPsFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLF-LLLYVIYKK 526
Cdd:COG0531   361 LVALAVIVLRRRRPDLPRP-FRVPLPLIPILGILLCLFLLYLLGPGALLIGLVLLAIgLLLYLLYRR 426
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
59-948 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1424.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856  59 NTIDVVPAYEHYANSTQPGEPRKVRPTLADLHSFLKQEGRHLHALAFDSRPSHEMTDGLVEDEAGTSSEKNPEEPVRFGW 138
Cdd:TIGR00930   1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAGAVKFGW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 139 VKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGS 218
Cdd:TIGR00930  81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 219 IGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPI-VDPINDIRIIGVVSVTVLLAISLAGMEWESK------------- 284
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETVLDLLRENGSKImVDPINDIRIYGTVTVVVLLGISFAGMEWENKaqvlflvivllsi 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 285 -------------------------------------------------------------------DPAVAIPKGTLMA 297
Cdd:TIGR00930 241 lnifvgtiipafdkpakgffglgneifsenfipgipgpeggffslfgiffpsvtgilaganisgdlkDPQKAIPKGTLLA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 298 IFWTTISYLAISATIGSCVVRDASGVLNDTMTPgwgACEGLACgygwnFTECTQQhSCRYGLINYYQTMSMVSGFAPLIT 377
Cdd:TIGR00930 321 ILTTTVVYLGSVVLFGACVVRDATGDKNDTLVT---NCTSAAC-----FSECAHN-TCSYGLMNNLQVMSLVSPFPPLIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 378 AGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLC 457
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLA 471
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 458 SYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQA 537
Cdd:TIGR00930 472 SYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQA 551
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 538 GSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLITNGHTK 617
Cdd:TIGR00930 552 LSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIQGPRLECVKEAQAAEAKIQT 631
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 618 WLNKRKIKAFYSDIIAEDLRKGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMRE 697
Cdd:TIGR00930 632 WLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSE 711
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 698 GLNVSkMMQAHINPVFDPAEDGKEASARGArpsvsgaldPEALVQEEQATTVFQSEQGKKTIDIYWLFDDGGLTLLIPYL 777
Cdd:TIGR00930 712 GLPIS-VLQVQEELENDCSEDSIELNDGKI---------STQPDMHLEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYL 781
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 778 LGRKKRWSKCKIRVFVGGQ-INRMDQERKAIISLLSKFRLGFHEVHILPDINQIPRAEHTKRFEDMIAPFRLNDGFKDEA 856
Cdd:TIGR00930 782 LTTKKVWKKCKIRIFVGAQkDDRSEQEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRLHKTEKDRE 861
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 857 TVN-EMRRDCPWKISDEEMRKNRVKSLRQVRLNEILLDYSRDAALVVITLPIGRKGECPSSLYMAWLETLSQDLrPPVIL 935
Cdd:TIGR00930 862 AKDpKMTWTKPWKITDAELQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDL-PPVLL 940
                         970
                  ....*....|...
gi 1059155856 936 IRGNQENVLTFYC 948
Cdd:TIGR00930 941 VRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
574-948 2.35e-171

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 504.84  E-value: 2.35e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 574 RPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELqlITNGHTKWLNKRKIKAFYSDIIAEDLRKGVQILMQAAGLGRMK 653
Cdd:pfam03522   1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSE--LQKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLK 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 654 PNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQA----------HINPVFDPAEDGKEAS 723
Cdd:pfam03522  79 PNILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDqdteelglgdETNSSYAEQSSEEQST 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 724 ARG------------------------ARPSVSGALDPEALVQEE---------------QATTVFQSEQGKKTIDIYWL 764
Cdd:pfam03522 159 SNSkqdddksklskkdsnlslspdkstKNPSGKDSSKSDKLKKKSpsiilrtasnekeilNNITQFQKKQKKGTIDVWWL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 765 FDDGGLTLLIPYLLGRKKRWSKCKIRVFVGG-QINRMDQERKAIISLLSKFRLGFHEVHILPDINQIPRAEHTKRFEDMI 843
Cdd:pfam03522 239 YDDGGLTLLLPYILSTRSKWSDCKLRVFALGnRKDELEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETKKFFDELI 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 844 APFRLNDGFKDEATVnemrrdcpWKISDEEMRKNRVKSLRQVRLNEILLDYSRDAALVVITLPIGRKGECPSSLYMAWLE 923
Cdd:pfam03522 319 EPFRLHEDDKEEESA--------EKITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLE 390
                         410       420
                  ....*....|....*....|....*
gi 1059155856 924 TLSQDLrPPVILIRGNQENVLTFYC 948
Cdd:pfam03522 391 TLTKDL-PPFLLVRGNQTSVLTFYS 414
AA_permease pfam00324
Amino acid permease;
141-565 5.55e-89

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 291.92  E-value: 5.55e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 141 GVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVkSGGTYFLISRSLGPELGGSIG 220
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 221 L------IFAFANAVGVAMHTVGFAETVRDLLQEYgapivdpindirIIGVVSVTVLLAISLAGMEW------------- 281
Cdd:pfam00324  80 WnywlswITVLALELTAASILIQFWELVPDIPYLW------------VWGAVFLVLLTIINLVGVKWygeaefwfaliki 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 282 -------------------------------------------------------------------ESKDPAVAIPKGT 294
Cdd:pfam00324 148 iaiigfiivgiillsggnpndgaifrylgdnggknnfppgfgkgfisvfviaffaftgielvgiaagEVKNPEKSIPKAI 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 295 LMAIFWTTISYLAISATIGSCVVRDASGVLNDTMTPgwgaceglacgygwnftectqqhscrYGLINYYQTMSMVSGFAP 374
Cdd:pfam00324 228 LQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASA--------------------------ASPFVIFFKFLGISGLAP 281
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 375 LITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPligFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIapIISNF 454
Cdd:pfam00324 282 LINAVILTAALSAANSSLYSGSRMLYSLARDGLAP---KFLKKVDKRGVPLRAILVSMVISLLALLLASLNPA--IVFNF 356
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 455 FLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSS 534
Cdd:pfam00324 357 LLAISGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAG 436
                         490       500       510
                  ....*....|....*....|....*....|.
gi 1059155856 535 VQAGSYNLALSYSVGLNEVEDHIKNYRPQCL 565
Cdd:pfam00324 437 SFAAAYLIVLLFLIILIGVKLHVKNWKPQLL 467
AA_permease_N pfam08403
Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid ...
45-116 5.11e-29

Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid permease domain (pfam00324) in metazoan Na-K-Cl cotransporters.


Pssm-ID: 429977  Cd Length: 70  Bit Score: 110.22  E-value: 5.11e-29
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1059155856  45 LTHGSTFCMRTFGYNTIDVVPAYEHYANSTQPGEPRKVRPTLADLHSFLkQEGRHLhALAFDSRPSHEMTDG 116
Cdd:pfam08403   1 DTHGSTYYLQTFGHNTLDAVPRIDFYRNTGSVSGVKKSRPSLAELHSQL-KKNSAL-AVAEGSVDGVENGDG 70
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
125-526 1.72e-20

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 95.35  E-value: 1.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 125 SSEKNPEEPVRFGWVKGVMIrCMLNIWGVILYLrLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNgKVKSGGTY 204
Cdd:COG0531     2 SRGESSELKRKLGLFDLVAL-GVGAIIGAGIFV-LPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASA-FPRAGGAY 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 205 FLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPIVDP----------INDIR-------IIGVVS 267
Cdd:COG0531    79 TYARRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFPAGGSVLIALvlillltllnLRGVKesakvnnILTVLK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 268 VTVLLAISLAGMEW-----------------------------------------ESKDPAVAIPKGTLMAIFWTTISYL 306
Cdd:COG0531   159 LLVLLLFIVVGLFAfdpanftpflpaggglsgvlaalalaffaftgfeaianlaeEAKNPKRNIPRAIILSLLIVGVLYI 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 307 AISATIGSCV----VRDASGVLNDTMTPGWGaceglacgygwnftectqqhscryglinyyqtmsmvSGFAPLITAGIFG 382
Cdd:COG0531   239 LVSLALTGVVpydeLAASGAPLADAAEAVFG------------------------------------PWGAILIALGALL 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 383 ATLSSALACLVSAAKVFQCLCEDQLYPliGFFGKGYGKNKEPVRGYLLAY--AIAVAFIIIAELNTIAPIISNFFLCSYA 460
Cdd:COG0531   283 SLLGALNASILGASRLLYAMARDGLLP--KVFAKVHPRFGTPVNAILLTGviALLLLLLGAASFTALASLASVGVLLAYL 360
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1059155856 461 LINFSCFHASITNSPGWRPsFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLF-LLLYVIYKK 526
Cdd:COG0531   361 LVALAVIVLRRRRPDLPRP-FRVPLPLIPILGILLCLFLLYLLGPGALLIGLVLLAIgLLLYLLYRR 426
AA_permease_2 pfam13520
Amino acid permease;
166-523 1.65e-04

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 44.99  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 166 AGIVLTWIIILLSvtvtSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETvrdL 245
Cdd:pfam13520  31 ALIVWGWIAAIIF----SLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNWFAYVLGLASSASVAASY---L 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 246 LQEYGAPIVDPINDIRIIGVVSVTVLLAISLAGMEWESK-DPAVAIPKGTLMAIFWTTISYLAISATIGSCVVRDASGVL 324
Cdd:pfam13520 104 LSALGPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKiQNILGILKLLLPLILIIILGLVTADGGGFNLLSGEWHTFF 183
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 325 NDTMTPGWGA-CEGLACGYGW----NFTECTQQHSCRYGLIN-------YYQTMSMV----------------------- 369
Cdd:pfam13520 184 PDGWPGVFAGfLGVLWSFTGFesaaNVSEEVKKRNVPKAIFIgviivgvLYILVNIAffgvvpddeialssglgqvaall 263
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 370 ------SGFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKgYGKNKEPVRGYLLAY-----AIAVAF 438
Cdd:pfam13520 264 fqavggKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAK-VNKFGSPIRAIILTAilsliLLLLFL 342
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1059155856 439 IIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPsfqYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFL 518
Cdd:pfam13520 343 LSPAAYNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRI---PGRWPVAIFGILFSLFLIVALFFPPVGPATGSSLNY 419

                  ....*
gi 1059155856 519 LLYVI 523
Cdd:pfam13520 420 AIILI 424
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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