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Conserved domains on  [gi|1034593617|ref|XP_016878423|]
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zinc finger CCCH domain-containing protein 18 isoform X8 [Homo sapiens]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 16058599)

zinc finger CCCH domain-containing protein similar to mammalian Zinc finger CCCH domain-containing protein 18 (ZC3H18) that interacts with ZFC3H1 in a RNase-insensitive manner

CATH:  4.10.1000.10
Gene Ontology:  GO:0046872|GO:0003676
PubMed:  12665246|27990022
SCOP:  3001741

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CCCH_4 pfam18044
CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and ...
 222-267 6.10e-04

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and one histidine to coordinate the zinc ion. This domain is found in a wide variety of proteins such as E3 ligases.


:

Pssm-ID: 465626  Cd Length: 22  Bit Score: 37.18  E-value: 6.10e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1034593617 222 PTCRFFMKdvvtplstllppisnsipfrgqvkGNCTWGMNCRFIHP 267
Cdd:pfam18044   1 RLCRYFQK------------------------GGCRYGDNCRFSHD 22
 
Name Accession Description Interval E-value
zf-CCCH_4 pfam18044
CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and ...
 222-267 6.10e-04

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and one histidine to coordinate the zinc ion. This domain is found in a wide variety of proteins such as E3 ligases.


Pssm-ID: 465626  Cd Length: 22  Bit Score: 37.18  E-value: 6.10e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1034593617 222 PTCRFFMKdvvtplstllppisnsipfrgqvkGNCTWGMNCRFIHP 267
Cdd:pfam18044   1 RLCRYFQK------------------------GGCRYGDNCRFSHD 22
 
Name Accession Description Interval E-value
zf-CCCH_4 pfam18044
CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and ...
 222-267 6.10e-04

CCCH-type zinc finger; This short zinc binding domain has the pattern of three cysteines and one histidine to coordinate the zinc ion. This domain is found in a wide variety of proteins such as E3 ligases.


Pssm-ID: 465626  Cd Length: 22  Bit Score: 37.18  E-value: 6.10e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1034593617 222 PTCRFFMKdvvtplstllppisnsipfrgqvkGNCTWGMNCRFIHP 267
Cdd:pfam18044   1 RLCRYFQK------------------------GGCRYGDNCRFSHD 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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