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Conserved domains on  [gi|1034593575|ref|XP_016878409|]
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dynein axonemal assembly factor 1 isoform X11 [Homo sapiens]

Protein Classification

ICP22 family protein( domain architecture ID 708738)

ICP22 family protein similar to Herpesvirus saimiri transcriptional regulator ICP22 homolog (also known as immediate-early protein) that regulates the transcription of alphaherpesviruses and their host genes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03169 super family cl27451
hypothetical protein; Provisional
 50-256 7.75e-03

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PHA03169:

Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 38.80  E-value: 7.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034593575  50 EKEERQQWESRERKKITDSIEALAMIKQRAEERKRQ--------RESQERGMRSAEDNSPRVPLRLGEMTSSDDGENVPA 121
Cdd:PHA03169   53 TSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGqggpsgsgSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPA 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034593575 122 SAEGKEEPPGDRETRQKMELFVKESFEAKDELCPEKPSGEEPPVEAKREDGGPEPEGTLPAET-LLLSSPVEVKGEDGDG 200
Cdd:PHA03169  133 SHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSeTPTSSPPPQSPPDEPG 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034593575 201 EPEGTLPAEAPPPPPPVEVKGEDGDQEPEGTLPAETLLLSPPVKVKGEDGDREPEG 256
Cdd:PHA03169  213 EPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVVGWKPSTRPGG 268
 
Name Accession Description Interval E-value
PHA03169 PHA03169
hypothetical protein; Provisional
 50-256 7.75e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 38.80  E-value: 7.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034593575  50 EKEERQQWESRERKKITDSIEALAMIKQRAEERKRQ--------RESQERGMRSAEDNSPRVPLRLGEMTSSDDGENVPA 121
Cdd:PHA03169   53 TSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGqggpsgsgSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPA 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034593575 122 SAEGKEEPPGDRETRQKMELFVKESFEAKDELCPEKPSGEEPPVEAKREDGGPEPEGTLPAET-LLLSSPVEVKGEDGDG 200
Cdd:PHA03169  133 SHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSeTPTSSPPPQSPPDEPG 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034593575 201 EPEGTLPAEAPPPPPPVEVKGEDGDQEPEGTLPAETLLLSPPVKVKGEDGDREPEG 256
Cdd:PHA03169  213 EPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVVGWKPSTRPGG 268
 
Name Accession Description Interval E-value
PHA03169 PHA03169
hypothetical protein; Provisional
 50-256 7.75e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 38.80  E-value: 7.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034593575  50 EKEERQQWESRERKKITDSIEALAMIKQRAEERKRQ--------RESQERGMRSAEDNSPRVPLRLGEMTSSDDGENVPA 121
Cdd:PHA03169   53 TSGPQVRAVAEQGHRQTESDTETAEESRHGEKEERGqggpsgsgSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPA 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034593575 122 SAEGKEEPPGDRETRQKMELFVKESFEAKDELCPEKPSGEEPPVEAKREDGGPEPEGTLPAET-LLLSSPVEVKGEDGDG 200
Cdd:PHA03169  133 SHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSeTPTSSPPPQSPPDEPG 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034593575 201 EPEGTLPAEAPPPPPPVEVKGEDGDQEPEGTLPAETLLLSPPVKVKGEDGDREPEG 256
Cdd:PHA03169  213 EPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVVGWKPSTRPGG 268
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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