endogenous retrovirus group K member 19 Env polyprotein-like [Homo sapiens]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| HERV-K_REC super family | cl24310 | Rec (regulator of expression encoded by corf) of HERV-K-113; REC is a family of rec proteins ... |
71-146 | 3.11e-12 | ||
Rec (regulator of expression encoded by corf) of HERV-K-113; REC is a family of rec proteins from the HERV-K viral polyprotein family. Rec is a functional homolog of Rev and Rex, and binds to an RNA element, the Rec-responsive element (RcRE), in the 3'LTR of HTDV/HERV-K transcripts. Thus Rec mediates nuclear export of RNA by binding to its responsive element, RcRE, present in a transcript. The human small glutamine-rich tetratricopeptide repeat-containing protein (hSGT) that controls mitotic processes and is a checkpoint protein during pro-metaphase is found to be a Rec-interacting partner.interferes with its role as a negative regulator of the androgen receptor, leading to enhanced androgen receptor activity. HERV-K(HML-2) elements benefit from this enhanced activity, as this leads to a vicious cycle that can result in increased cell proliferation, an inhibition of apoptosis, and eventually tumourigenesis. The actual alignment was detected with superfamily member pfam15695: Pssm-ID: 292323 Cd Length: 87 Bit Score: 59.88 E-value: 3.11e-12
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| HERV-K_env_2 super family | cl16410 | Retro-transcribing viruses envelope glycoprotein; This family comes from human endogenous ... |
157-192 | 1.06e-11 | ||
Retro-transcribing viruses envelope glycoprotein; This family comes from human endogenous retrovirus K envelope glycoproteins. The actual alignment was detected with superfamily member pfam13804: Pssm-ID: 290518 Cd Length: 169 Bit Score: 60.53 E-value: 1.06e-11
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| Name | Accession | Description | Interval | E-value | ||
| HERV-K_REC | pfam15695 | Rec (regulator of expression encoded by corf) of HERV-K-113; REC is a family of rec proteins ... |
71-146 | 3.11e-12 | ||
Rec (regulator of expression encoded by corf) of HERV-K-113; REC is a family of rec proteins from the HERV-K viral polyprotein family. Rec is a functional homolog of Rev and Rex, and binds to an RNA element, the Rec-responsive element (RcRE), in the 3'LTR of HTDV/HERV-K transcripts. Thus Rec mediates nuclear export of RNA by binding to its responsive element, RcRE, present in a transcript. The human small glutamine-rich tetratricopeptide repeat-containing protein (hSGT) that controls mitotic processes and is a checkpoint protein during pro-metaphase is found to be a Rec-interacting partner.interferes with its role as a negative regulator of the androgen receptor, leading to enhanced androgen receptor activity. HERV-K(HML-2) elements benefit from this enhanced activity, as this leads to a vicious cycle that can result in increased cell proliferation, an inhibition of apoptosis, and eventually tumourigenesis. Pssm-ID: 292323 Cd Length: 87 Bit Score: 59.88 E-value: 3.11e-12
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| HERV-K_env_2 | pfam13804 | Retro-transcribing viruses envelope glycoprotein; This family comes from human endogenous ... |
157-192 | 1.06e-11 | ||
Retro-transcribing viruses envelope glycoprotein; This family comes from human endogenous retrovirus K envelope glycoproteins. Pssm-ID: 290518 Cd Length: 169 Bit Score: 60.53 E-value: 1.06e-11
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| Name | Accession | Description | Interval | E-value | ||
| HERV-K_REC | pfam15695 | Rec (regulator of expression encoded by corf) of HERV-K-113; REC is a family of rec proteins ... |
71-146 | 3.11e-12 | ||
Rec (regulator of expression encoded by corf) of HERV-K-113; REC is a family of rec proteins from the HERV-K viral polyprotein family. Rec is a functional homolog of Rev and Rex, and binds to an RNA element, the Rec-responsive element (RcRE), in the 3'LTR of HTDV/HERV-K transcripts. Thus Rec mediates nuclear export of RNA by binding to its responsive element, RcRE, present in a transcript. The human small glutamine-rich tetratricopeptide repeat-containing protein (hSGT) that controls mitotic processes and is a checkpoint protein during pro-metaphase is found to be a Rec-interacting partner.interferes with its role as a negative regulator of the androgen receptor, leading to enhanced androgen receptor activity. HERV-K(HML-2) elements benefit from this enhanced activity, as this leads to a vicious cycle that can result in increased cell proliferation, an inhibition of apoptosis, and eventually tumourigenesis. Pssm-ID: 292323 Cd Length: 87 Bit Score: 59.88 E-value: 3.11e-12
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| HERV-K_env_2 | pfam13804 | Retro-transcribing viruses envelope glycoprotein; This family comes from human endogenous ... |
157-192 | 1.06e-11 | ||
Retro-transcribing viruses envelope glycoprotein; This family comes from human endogenous retrovirus K envelope glycoproteins. Pssm-ID: 290518 Cd Length: 169 Bit Score: 60.53 E-value: 1.06e-11
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| Blast search parameters | ||||
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