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Conserved domains on  [gi|1025048637|ref|XP_016447037|]
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PREDICTED: protein RADIALIS-like 5 [Nicotiana tabacum]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 10073748)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein binds DNA and may function as a transcription factor

CATH:  1.20.58.1880
Gene Ontology:  GO:0006355|GO:0003677|GO:0003700
PubMed:  8882580|15040448|16877755
SCOP:  4000317

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 3-50 1.18e-07

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 43.72  E-value: 1.18e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1025048637  3 TWTAKQNKKFEEALALYDKDtsdRWNNIARCVGGKSAEEVRRHYELLV 50
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERWRNLL 45
COG5114 super family cl27155
Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics];
27-81 9.65e-03

Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics];


The actual alignment was detected with superfamily member COG5114:

Pssm-ID: 227445 [Multi-domain]  Cd Length: 432  Bit Score: 33.50  E-value: 9.65e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1025048637  27 WNNIARCVGGKSAEEVRRHYellVKdiMQIENDQVPLPNYRTAGSDGRGYANEQR 81
Cdd:COG5114    86 WEDIADYIGSRAKEEIKSHY---LK--MYDESKYYPLPDITQNIHVPQDEFLEQR 135
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 3-50 1.18e-07

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 43.72  E-value: 1.18e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1025048637  3 TWTAKQNKKFEEALALYDKDtsdRWNNIARCVGGKSAEEVRRHYELLV 50
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
3-51 3.48e-07

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 42.60  E-value: 3.48e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1025048637   3 TWTAKQNKKFEEALALYDKDtsdRWNNIARCVGGKSAEEVRRHYELLVK 51
Cdd:smart00717  3 EWTEEEDELLIELVKKYGKN---NWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 4-46 1.80e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.25  E-value: 1.80e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 1025048637  4 WTAKQNKKFEEALALYDKdtsdRWNNIARCVGGKSAEEVRRHY 46
Cdd:pfam00249  4 WTPEEDELLLEAVEKLGN----RWKKIAKLLPGRTDNQCKNRW 42
COG5114 COG5114
Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics];
27-81 9.65e-03

Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics];


Pssm-ID: 227445 [Multi-domain]  Cd Length: 432  Bit Score: 33.50  E-value: 9.65e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1025048637  27 WNNIARCVGGKSAEEVRRHYellVKdiMQIENDQVPLPNYRTAGSDGRGYANEQR 81
Cdd:COG5114    86 WEDIADYIGSRAKEEIKSHY---LK--MYDESKYYPLPDITQNIHVPQDEFLEQR 135
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 3-50 1.18e-07

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 43.72  E-value: 1.18e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 1025048637  3 TWTAKQNKKFEEALALYDKDtsdRWNNIARCVGGKSAEEVRRHYELLV 50
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKN---NWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
3-51 3.48e-07

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 42.60  E-value: 3.48e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1025048637   3 TWTAKQNKKFEEALALYDKDtsdRWNNIARCVGGKSAEEVRRHYELLVK 51
Cdd:smart00717  3 EWTEEEDELLIELVKKYGKN---NWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 4-46 1.80e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 38.25  E-value: 1.80e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 1025048637  4 WTAKQNKKFEEALALYDKdtsdRWNNIARCVGGKSAEEVRRHY 46
Cdd:pfam00249  4 WTPEEDELLLEAVEKLGN----RWKKIAKLLPGRTDNQCKNRW 42
COG5114 COG5114
Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics];
27-81 9.65e-03

Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics];


Pssm-ID: 227445 [Multi-domain]  Cd Length: 432  Bit Score: 33.50  E-value: 9.65e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1025048637  27 WNNIARCVGGKSAEEVRRHYellVKdiMQIENDQVPLPNYRTAGSDGRGYANEQR 81
Cdd:COG5114    86 WEDIADYIGSRAKEEIKSHY---LK--MYDESKYYPLPDITQNIHVPQDEFLEQR 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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