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Conserved domains on  [gi|1025367231|ref|XP_016396789|]
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PREDICTED: glypican-1-like [Sinocyclocheilus rhinocerous]

Protein Classification

glypican family protein( domain architecture ID 10471748)

glypican family protein is a cell surface proteoglycan that bears heparan sulfate, similar to human glypican-1 that binds alpha-4 (V) collagen and participates in Schwann cell myelination

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Glypican pfam01153
Glypican;
6-539 0e+00

Glypican;


:

Pssm-ID: 460084  Cd Length: 554  Bit Score: 735.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231   6 LVLLCALTGL-VFGDSKPKTCSDLRQFYSSKGFSLNGVPQTEIFGEHLRVCSQGYTCCTSGMEENLLNLSRREFETQVKE 84
Cdd:pfam01153   1 LLLLLALPGRaDPASGKARSCSEVRQLYSAKGFSLNDVPQSEISGEHLRICPQGYTCCTSEMEEKLSNQSRREFEQLVHE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231  85 SGRTLQASLNGQFKSFDDYFLELLNRSEASLQTSFQAGFGSLFSQTAKVFQDLYSDLRHYYRGSNVNLEEALNEFWARLL 164
Cdd:pfam01153  81 ASSSLQTTLTTNHRKFDEFFRELLNISENSLNDMFVRTYGRLYTQNAELFKDLFTELRRYYRGSNVNLEEALNEFWARLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 165 ERLFKALNTQYIIGEEYLECVAKQSETLKPLGDTPRELKTKITRTVIAARTFAQGLVISGEAVRKVSQVYMSTECVHAIM 244
Cdd:pfam01153 161 ERLFKLVNPQYHFSDDYLECLSKQTEQLKPFGDVPRKLKLQLTRAFIAARAFVQGLNLGREVVNKVSQVPLSPECTRALM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 245 KMSYCPHCSGVAFAKPCSNYCRNVMKGCLANQADLDSEWRNLADAMLEVVDKLSRPYSVDSVVLSLPKRIAEAILYMQDN 324
Cdd:pfam01153 241 KMLYCPHCRGLPSVKPCYNYCLNVMRGCLANQADLDTEWRNFIDSLLLVAERLEGPFNIENVIDSIHVKISEAIMNMQEN 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 325 LNTFNNKVFQACGSPVQ-------SSNSEDQIKRGTNTAEEVSGTP---GAQLEKLLSDVSRMLRDMMQYWVHLPRKLCV 394
Cdd:pfam01153 321 SMKLTAKVFQGCGTPKPtpyrstrSSSPEEKKKRGFRTYTPEERPTtaaGTRLDRLVTDVKEKLKEMKSFWSTLPDTLCS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 395 DRE--SGPSETDRCWNGMNVDRYLPDVMGNGLASQINNPEVEIDITKPDMTVRKQIMQLKIMINRLKYAINGNDVDFQDT 472
Cdd:pfam01153 401 DEKmaADPTNEDKCWNGQTKGRYLPEVMGNGLANQINNPEVEVDITKPDMVIRQQIMKLKIMTNRLKNAYPGNDVDFQDD 480

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1025367231 473 SDDISGSGSGM-CADDQCSRDTRLSAPNTDKPNVYGYP--SENKKVVKGRSSQNLP----CVSLCLLSLVTVLL 539
Cdd:pfam01153 481 SDDSSGSGSGDgCPSDLCKGDLPFVFELTDTPATPAKPttQQGTGSVDGSSTGGLPssllLATSMLLSLVTLLV 554
 
Name Accession Description Interval E-value
Glypican pfam01153
Glypican;
6-539 0e+00

Glypican;


Pssm-ID: 460084  Cd Length: 554  Bit Score: 735.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231   6 LVLLCALTGL-VFGDSKPKTCSDLRQFYSSKGFSLNGVPQTEIFGEHLRVCSQGYTCCTSGMEENLLNLSRREFETQVKE 84
Cdd:pfam01153   1 LLLLLALPGRaDPASGKARSCSEVRQLYSAKGFSLNDVPQSEISGEHLRICPQGYTCCTSEMEEKLSNQSRREFEQLVHE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231  85 SGRTLQASLNGQFKSFDDYFLELLNRSEASLQTSFQAGFGSLFSQTAKVFQDLYSDLRHYYRGSNVNLEEALNEFWARLL 164
Cdd:pfam01153  81 ASSSLQTTLTTNHRKFDEFFRELLNISENSLNDMFVRTYGRLYTQNAELFKDLFTELRRYYRGSNVNLEEALNEFWARLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 165 ERLFKALNTQYIIGEEYLECVAKQSETLKPLGDTPRELKTKITRTVIAARTFAQGLVISGEAVRKVSQVYMSTECVHAIM 244
Cdd:pfam01153 161 ERLFKLVNPQYHFSDDYLECLSKQTEQLKPFGDVPRKLKLQLTRAFIAARAFVQGLNLGREVVNKVSQVPLSPECTRALM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 245 KMSYCPHCSGVAFAKPCSNYCRNVMKGCLANQADLDSEWRNLADAMLEVVDKLSRPYSVDSVVLSLPKRIAEAILYMQDN 324
Cdd:pfam01153 241 KMLYCPHCRGLPSVKPCYNYCLNVMRGCLANQADLDTEWRNFIDSLLLVAERLEGPFNIENVIDSIHVKISEAIMNMQEN 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 325 LNTFNNKVFQACGSPVQ-------SSNSEDQIKRGTNTAEEVSGTP---GAQLEKLLSDVSRMLRDMMQYWVHLPRKLCV 394
Cdd:pfam01153 321 SMKLTAKVFQGCGTPKPtpyrstrSSSPEEKKKRGFRTYTPEERPTtaaGTRLDRLVTDVKEKLKEMKSFWSTLPDTLCS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 395 DRE--SGPSETDRCWNGMNVDRYLPDVMGNGLASQINNPEVEIDITKPDMTVRKQIMQLKIMINRLKYAINGNDVDFQDT 472
Cdd:pfam01153 401 DEKmaADPTNEDKCWNGQTKGRYLPEVMGNGLANQINNPEVEVDITKPDMVIRQQIMKLKIMTNRLKNAYPGNDVDFQDD 480

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1025367231 473 SDDISGSGSGM-CADDQCSRDTRLSAPNTDKPNVYGYP--SENKKVVKGRSSQNLP----CVSLCLLSLVTVLL 539
Cdd:pfam01153 481 SDDSSGSGSGDgCPSDLCKGDLPFVFELTDTPATPAKPttQQGTGSVDGSSTGGLPssllLATSMLLSLVTLLV 554
 
Name Accession Description Interval E-value
Glypican pfam01153
Glypican;
6-539 0e+00

Glypican;


Pssm-ID: 460084  Cd Length: 554  Bit Score: 735.72  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231   6 LVLLCALTGL-VFGDSKPKTCSDLRQFYSSKGFSLNGVPQTEIFGEHLRVCSQGYTCCTSGMEENLLNLSRREFETQVKE 84
Cdd:pfam01153   1 LLLLLALPGRaDPASGKARSCSEVRQLYSAKGFSLNDVPQSEISGEHLRICPQGYTCCTSEMEEKLSNQSRREFEQLVHE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231  85 SGRTLQASLNGQFKSFDDYFLELLNRSEASLQTSFQAGFGSLFSQTAKVFQDLYSDLRHYYRGSNVNLEEALNEFWARLL 164
Cdd:pfam01153  81 ASSSLQTTLTTNHRKFDEFFRELLNISENSLNDMFVRTYGRLYTQNAELFKDLFTELRRYYRGSNVNLEEALNEFWARLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 165 ERLFKALNTQYIIGEEYLECVAKQSETLKPLGDTPRELKTKITRTVIAARTFAQGLVISGEAVRKVSQVYMSTECVHAIM 244
Cdd:pfam01153 161 ERLFKLVNPQYHFSDDYLECLSKQTEQLKPFGDVPRKLKLQLTRAFIAARAFVQGLNLGREVVNKVSQVPLSPECTRALM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 245 KMSYCPHCSGVAFAKPCSNYCRNVMKGCLANQADLDSEWRNLADAMLEVVDKLSRPYSVDSVVLSLPKRIAEAILYMQDN 324
Cdd:pfam01153 241 KMLYCPHCRGLPSVKPCYNYCLNVMRGCLANQADLDTEWRNFIDSLLLVAERLEGPFNIENVIDSIHVKISEAIMNMQEN 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 325 LNTFNNKVFQACGSPVQ-------SSNSEDQIKRGTNTAEEVSGTP---GAQLEKLLSDVSRMLRDMMQYWVHLPRKLCV 394
Cdd:pfam01153 321 SMKLTAKVFQGCGTPKPtpyrstrSSSPEEKKKRGFRTYTPEERPTtaaGTRLDRLVTDVKEKLKEMKSFWSTLPDTLCS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1025367231 395 DRE--SGPSETDRCWNGMNVDRYLPDVMGNGLASQINNPEVEIDITKPDMTVRKQIMQLKIMINRLKYAINGNDVDFQDT 472
Cdd:pfam01153 401 DEKmaADPTNEDKCWNGQTKGRYLPEVMGNGLANQINNPEVEVDITKPDMVIRQQIMKLKIMTNRLKNAYPGNDVDFQDD 480

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1025367231 473 SDDISGSGSGM-CADDQCSRDTRLSAPNTDKPNVYGYP--SENKKVVKGRSSQNLP----CVSLCLLSLVTVLL 539
Cdd:pfam01153 481 SDDSSGSGSGDgCPSDLCKGDLPFVFELTDTPATPAKPttQQGTGSVDGSSTGGLPssllLATSMLLSLVTLLV 554
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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