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Conserved domains on  [gi|1012191893|ref|XP_015970845|]
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transcription factor MYB60 [Arachis duranensis]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 1000535)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein may be involved in the regulation of gene expression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03212 super family cl31985
Transcription repressor MYB5; Provisional
 5-111 2.06e-47

Transcription repressor MYB5; Provisional


The actual alignment was detected with superfamily member PLN03212:

Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 161.01  E-value: 2.06e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012191893   5 PCCDKVGIKKGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGLSRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIHLQAL 84
Cdd:PLN03212   16 PCCTKMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRL 95

                          90       100
                  ....*....|....*....|....*..
gi 1012191893  85 LGNKWAAIASYLPQRTDNDIKNYWNTH 111
Cdd:PLN03212   96 LGNRWSLIAGRIPGRTDNEIKNYWNTH 122
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 5-111 2.06e-47

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 161.01  E-value: 2.06e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012191893   5 PCCDKVGIKKGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGLSRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIHLQAL 84
Cdd:PLN03212   16 PCCTKMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRL 95

                          90       100
                  ....*....|....*....|....*..
gi 1012191893  85 LGNKWAAIASYLPQRTDNDIKNYWNTH 111
Cdd:PLN03212   96 LGNRWSLIAGRIPGRTDNEIKNYWNTH 122
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 9-109 2.22e-18

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 85.99  E-value: 2.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012191893   9 KVGIKKGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGlSRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIHLQALLGNK 88
Cdd:COG5147    15 QTKRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLI-SSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ 93

                          90       100
                  ....*....|....*....|.
gi 1012191893  89 WAAIASYLPQRTDNDIKNYWN 109
Cdd:COG5147    94 WSTIADYKDRRTAQQCVERYV 114
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 14-61 1.13e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 61.75  E-value: 1.13e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1012191893  14 KGPWTPEEDIILVSYIQEHGpGNWRSVPTNTGlSRCSKSCRLRWTNYL 61
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLP-GRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
14-63 5.84e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 59.93  E-value: 5.84e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1012191893   14 KGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGlSRCSKSCRLRWTNYLRP 63
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 16-61 5.07e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 57.20  E-value: 5.07e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1012191893  16 PWTPEEDIILVSYIQEHGPGNWRSVPTNTGlSRCSKSCRLRWTNYL 61
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 5-111 2.06e-47

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 161.01  E-value: 2.06e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012191893   5 PCCDKVGIKKGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGLSRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIHLQAL 84
Cdd:PLN03212   16 PCCTKMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRL 95

                          90       100
                  ....*....|....*....|....*..
gi 1012191893  85 LGNKWAAIASYLPQRTDNDIKNYWNTH 111
Cdd:PLN03212   96 LGNRWSLIAGRIPGRTDNEIKNYWNTH 122
PLN03091 PLN03091
hypothetical protein; Provisional
 1-110 5.58e-43

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 154.75  E-value: 5.58e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012191893   1 MGRPPCCDKVGIKKGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGLSRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIH 80
Cdd:PLN03091    1 MGRHSCCYKQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIE 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 1012191893  81 LQALLGNKWAAIASYLPQRTDNDIKNYWNT 110
Cdd:PLN03091   81 LHAVLGNRWSQIAAQLPGRTDNEIKNLWNS 110
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 9-109 2.22e-18

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 85.99  E-value: 2.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1012191893   9 KVGIKKGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGlSRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIHLQALLGNK 88
Cdd:COG5147    15 QTKRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLI-SSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ 93

                          90       100
                  ....*....|....*....|.
gi 1012191893  89 WAAIASYLPQRTDNDIKNYWN 109
Cdd:COG5147    94 WSTIADYKDRRTAQQCVERYV 114
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 14-61 1.13e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 61.75  E-value: 1.13e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1012191893  14 KGPWTPEEDIILVSYIQEHGpGNWRSVPTNTGlSRCSKSCRLRWTNYL 61
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLP-GRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
14-63 5.84e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 59.93  E-value: 5.84e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1012191893   14 KGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGlSRCSKSCRLRWTNYLRP 63
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 67-111 1.92e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 58.28  E-value: 1.92e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1012191893  67 RGNFTPHEEGMIIHLQALLGNKWAAIASYLPQRTDNDIKNYWNTH 111
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNY 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 16-61 5.07e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 57.20  E-value: 5.07e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1012191893  16 PWTPEEDIILVSYIQEHGPGNWRSVPTNTGlSRCSKSCRLRWTNYL 61
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 17-75 1.08e-08

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 51.16  E-value: 1.08e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1012191893  17 WTPEEDIILVSYIQEHGpGNWRSVPTNTGlSRCSKSCRLRWTNYLRPGIKRGNFTPHEE 75
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPKISRGPWSKEED 57
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
67-111 2.15e-08

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 49.91  E-value: 2.15e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1012191893   67 RGNFTPHEEGMIIHLQALLG-NKWAAIASYLPQRTDNDIKNYWNTH 111
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 69-111 2.15e-08

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 49.50  E-value: 2.15e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1012191893  69 NFTPHEEGMIIHLQALLG-NKWAAIASYLPQRTDNDIKNYWNTH 111
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNL 44
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 13-79 5.88e-04

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 41.70  E-value: 5.88e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1012191893  13 KKGPWTPEEDIILVSYIQEHGPgnwRSVPTNTGLSRCSKSCRLRWTNYLRPG--IKRGNFTPHEEGMII 79
Cdd:COG5147   290 QRGKWTKEEEQELAKLVVEHGG---SWTEIGKLLGRMPNDCRDRWRDYVKCGdtLKRNRWSIEEEELLD 355
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 16-38 1.38e-03

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 36.39  E-value: 1.38e-03
                          10        20
                  ....*....|....*....|...
gi 1012191893  16 PWTPEEDIILVSYIQEHGPGNWR 38
Cdd:cd11660     2 KWTDEEDEALVEGVEKYGVGNWA 24
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 70-111 1.67e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 36.52  E-value: 1.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1012191893  70 FTPHEEGMIIHLQALLGNKWAAIASYLPQRTDNDIKNYWNTH 111
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRK 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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