NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1002243632|ref|XP_015626044|]
View 

putative disease resistance protein RGA4 [Oryza sativa Japonica Group]

Protein Classification

NB-LRR family disease resistance protein( domain architecture ID 16524883)

NB-LRR (nucleotide-binding-leucine rich repeat) family disease resistance protein guards the plant against pathogens via an indirect interaction with an avirulence protein contained in the plant, triggering a defense response that restricts the pathogen growth

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
NB-ARC super family cl26397
NB-ARC domain;
220-469 1.36e-30

NB-ARC domain;


The actual alignment was detected with superfamily member pfam00931:

Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 121.33  E-value: 1.36e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  220 ESIPVLPIVGIGGVGKTTMAQHILHD-PRVISHFDMIIWICVSDDFdvkrlTKEAIQSSskkesttfDGKRITKEAIQSY 298
Cdd:pfam00931   16 DEPGIVGIHGMGGVGKTTLAAQIFNDfDEVEGHFDSVAWVVVSKTF-----TISTLQQT--------ILQNLGLSEDDWD 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  299 SKKESTAdhLDSLQHALsekvRDKTLLIILDDMWDDALresgrcWKRFCAPFSNVlAQGSIMLVTTRSLEVAHEVK-TME 377
Cdd:pfam00931   83 NKEEGEL--ARKIRRAL----LTKRFLLVLDDVWDEED------WDKIGIPLPDR-ENGCRVLLTTRSEEVAGRVGgPSD 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  378 PVRLEGLKDDIFWNFFKICTFGSSDSSDyPELERIGRNIVPKLKGSPLAAKTLGRLLRTSLDIAHWNNILQSELWELRQH 457
Cdd:pfam00931  150 PHEVELLEPDEAWELFENKVFPKTLGEC-ELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKTVEEWKHVYDVLQSELKSN 228
                          250
                   ....*....|....*
gi 1002243632  458 NTE---ILPALRLSY 469
Cdd:pfam00931  229 SYSlnsVRSILQLSY 243
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
582-698 3.23e-07

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 54.17  E-value: 3.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  582 TNFDCNLLLSLCKHKKLRTL-LCHRSLQDktlacvMDRWCTELQHMRVIVCPYTK--ELPASIGKLKHLRYLKISgDCPF 658
Cdd:COG4886     99 TELDLSGNEELSNLTNLESLdLSGNQLTD------LPEELANLTNLKELDLSNNQltDLPEPLGNLTNLKSLDLS-NNQL 171
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1002243632  659 KSLPQEFCHLYNLQIFSATKCRLENLPSDFNKLRNLRRFD 698
Cdd:COG4886    172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELD 211
ClpA super family cl33938
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
176-254 3.09e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG0542:

Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.07  E-value: 3.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  176 IFGRDNELQQVMELLGvpkngtdarskRRRKNNdeststsrcnqesiPVLpivgIG--GVGKTT----MAQHI------- 242
Cdd:COG0542    181 VIGRDEEIRRVIQILS-----------RRTKNN--------------PVL----IGepGVGKTAivegLAQRIvngdvpe 231
                           90
                   ....*....|...
gi 1002243632  243 -LHDPRVIShFDM 254
Cdd:COG0542    232 sLKDKRVLS-LDL 243
Rx_N pfam18052
Rx N-terminal domain; This entry represents the N-terminal domain found in many plant ...
53-101 2.96e-03

Rx N-terminal domain; This entry represents the N-terminal domain found in many plant resistance proteins. This domain has been predicted to be a coiled-coil, however the structure shows that it adopts a four helical bundle fold.


:

Pssm-ID: 436239  Cd Length: 93  Bit Score: 38.02  E-value: 2.96e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1002243632   53 LQCLRDTLPAKYDLIDRAEWRSH-ERRVAELLPNLKDAMYNADDLLDEFR 101
Cdd:pfam18052   27 LEKLKDELESIQAFLEDAERKQItDEQVKLWLKQLRDVAYDAEDVLDEFL 76
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
786-999 8.17e-03

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.92  E-value: 8.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  786 TSLSYLNLTGCPGEFLPTWFhpSNLPMLTSLELIACHdfVTiptpsmsqsidpnEIPKVLTEnnkgrpgiFSSLNHVIIe 865
Cdd:COG4886    113 TNLESLDLSGNQLTDLPEEL--ANLTNLKELDLSNNQ--LT-------------DLPEPLGN--------LTNLKSLDL- 166
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  866 SCNKLSNLDQFLqpAYLPAIKTIKITKCrQLVELPTDrLGEFHFLEELEVSHCpNLNDpQSLSIPTLKKLKLIN-SWNLL 944
Cdd:COG4886    167 SNNQLTDLPEEL--GNLTNLKELDLSNN-QITDLPEP-LGNLTNLEELDLSGN-QLTD-LPEPLANLTNLETLDlSNNQL 240
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1002243632  945 gdieccsltslvfslwhvTSIPlhvWSSSFPALQKLQIADSGITGESQSSVLTSL 999
Cdd:COG4886    241 ------------------TDLP---ELGNLTNLEELDLSNNQLTDLPPLANLTNL 274
 
Name Accession Description Interval E-value
NB-ARC pfam00931
NB-ARC domain;
220-469 1.36e-30

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 121.33  E-value: 1.36e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  220 ESIPVLPIVGIGGVGKTTMAQHILHD-PRVISHFDMIIWICVSDDFdvkrlTKEAIQSSskkesttfDGKRITKEAIQSY 298
Cdd:pfam00931   16 DEPGIVGIHGMGGVGKTTLAAQIFNDfDEVEGHFDSVAWVVVSKTF-----TISTLQQT--------ILQNLGLSEDDWD 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  299 SKKESTAdhLDSLQHALsekvRDKTLLIILDDMWDDALresgrcWKRFCAPFSNVlAQGSIMLVTTRSLEVAHEVK-TME 377
Cdd:pfam00931   83 NKEEGEL--ARKIRRAL----LTKRFLLVLDDVWDEED------WDKIGIPLPDR-ENGCRVLLTTRSEEVAGRVGgPSD 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  378 PVRLEGLKDDIFWNFFKICTFGSSDSSDyPELERIGRNIVPKLKGSPLAAKTLGRLLRTSLDIAHWNNILQSELWELRQH 457
Cdd:pfam00931  150 PHEVELLEPDEAWELFENKVFPKTLGEC-ELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKTVEEWKHVYDVLQSELKSN 228
                          250
                   ....*....|....*
gi 1002243632  458 NTE---ILPALRLSY 469
Cdd:pfam00931  229 SYSlnsVRSILQLSY 243
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
582-698 3.23e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 54.17  E-value: 3.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  582 TNFDCNLLLSLCKHKKLRTL-LCHRSLQDktlacvMDRWCTELQHMRVIVCPYTK--ELPASIGKLKHLRYLKISgDCPF 658
Cdd:COG4886     99 TELDLSGNEELSNLTNLESLdLSGNQLTD------LPEELANLTNLKELDLSNNQltDLPEPLGNLTNLKSLDLS-NNQL 171
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1002243632  659 KSLPQEFCHLYNLQIFSATKCRLENLPSDFNKLRNLRRFD 698
Cdd:COG4886    172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELD 211
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
176-254 3.09e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.07  E-value: 3.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  176 IFGRDNELQQVMELLGvpkngtdarskRRRKNNdeststsrcnqesiPVLpivgIG--GVGKTT----MAQHI------- 242
Cdd:COG0542    181 VIGRDEEIRRVIQILS-----------RRTKNN--------------PVL----IGepGVGKTAivegLAQRIvngdvpe 231
                           90
                   ....*....|...
gi 1002243632  243 -LHDPRVIShFDM 254
Cdd:COG0542    232 sLKDKRVLS-LDL 243
Rx_N pfam18052
Rx N-terminal domain; This entry represents the N-terminal domain found in many plant ...
53-101 2.96e-03

Rx N-terminal domain; This entry represents the N-terminal domain found in many plant resistance proteins. This domain has been predicted to be a coiled-coil, however the structure shows that it adopts a four helical bundle fold.


Pssm-ID: 436239  Cd Length: 93  Bit Score: 38.02  E-value: 2.96e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1002243632   53 LQCLRDTLPAKYDLIDRAEWRSH-ERRVAELLPNLKDAMYNADDLLDEFR 101
Cdd:pfam18052   27 LEKLKDELESIQAFLEDAERKQItDEQVKLWLKQLRDVAYDAEDVLDEFL 76
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
786-999 8.17e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.92  E-value: 8.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  786 TSLSYLNLTGCPGEFLPTWFhpSNLPMLTSLELIACHdfVTiptpsmsqsidpnEIPKVLTEnnkgrpgiFSSLNHVIIe 865
Cdd:COG4886    113 TNLESLDLSGNQLTDLPEEL--ANLTNLKELDLSNNQ--LT-------------DLPEPLGN--------LTNLKSLDL- 166
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  866 SCNKLSNLDQFLqpAYLPAIKTIKITKCrQLVELPTDrLGEFHFLEELEVSHCpNLNDpQSLSIPTLKKLKLIN-SWNLL 944
Cdd:COG4886    167 SNNQLTDLPEEL--GNLTNLKELDLSNN-QITDLPEP-LGNLTNLEELDLSGN-QLTD-LPEPLANLTNLETLDlSNNQL 240
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1002243632  945 gdieccsltslvfslwhvTSIPlhvWSSSFPALQKLQIADSGITGESQSSVLTSL 999
Cdd:COG4886    241 ------------------TDLP---ELGNLTNLEELDLSNNQLTDLPPLANLTNL 274
 
Name Accession Description Interval E-value
NB-ARC pfam00931
NB-ARC domain;
220-469 1.36e-30

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 121.33  E-value: 1.36e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  220 ESIPVLPIVGIGGVGKTTMAQHILHD-PRVISHFDMIIWICVSDDFdvkrlTKEAIQSSskkesttfDGKRITKEAIQSY 298
Cdd:pfam00931   16 DEPGIVGIHGMGGVGKTTLAAQIFNDfDEVEGHFDSVAWVVVSKTF-----TISTLQQT--------ILQNLGLSEDDWD 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  299 SKKESTAdhLDSLQHALsekvRDKTLLIILDDMWDDALresgrcWKRFCAPFSNVlAQGSIMLVTTRSLEVAHEVK-TME 377
Cdd:pfam00931   83 NKEEGEL--ARKIRRAL----LTKRFLLVLDDVWDEED------WDKIGIPLPDR-ENGCRVLLTTRSEEVAGRVGgPSD 149
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  378 PVRLEGLKDDIFWNFFKICTFGSSDSSDyPELERIGRNIVPKLKGSPLAAKTLGRLLRTSLDIAHWNNILQSELWELRQH 457
Cdd:pfam00931  150 PHEVELLEPDEAWELFENKVFPKTLGEC-ELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKTVEEWKHVYDVLQSELKSN 228
                          250
                   ....*....|....*
gi 1002243632  458 NTE---ILPALRLSY 469
Cdd:pfam00931  229 SYSlnsVRSILQLSY 243
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
582-698 3.23e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 54.17  E-value: 3.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  582 TNFDCNLLLSLCKHKKLRTL-LCHRSLQDktlacvMDRWCTELQHMRVIVCPYTK--ELPASIGKLKHLRYLKISgDCPF 658
Cdd:COG4886     99 TELDLSGNEELSNLTNLESLdLSGNQLTD------LPEELANLTNLKELDLSNNQltDLPEPLGNLTNLKSLDLS-NNQL 171
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1002243632  659 KSLPQEFCHLYNLQIFSATKCRLENLPSDFNKLRNLRRFD 698
Cdd:COG4886    172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELD 211
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
635-698 3.81e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 53.78  E-value: 3.81e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002243632  635 KELPASIGKLKHLRYLKISgDCPFKSLPQEFCHLYNLQIFSATKCRLENLPSDFNKLRNLRRFD 698
Cdd:COG4886    172 TDLPEELGNLTNLKELDLS-NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLD 234
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
635-698 4.37e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 47.24  E-value: 4.37e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002243632  635 KELPASIGKLKHLRYLKISGdCPFKSLPQEFCHLYNLQIFSATKCRLENLPSdFNKLRNLRRFD 698
Cdd:COG4886    195 TDLPEPLGNLTNLEELDLSG-NQLTDLPEPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELD 256
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
176-254 3.09e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.07  E-value: 3.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  176 IFGRDNELQQVMELLGvpkngtdarskRRRKNNdeststsrcnqesiPVLpivgIG--GVGKTT----MAQHI------- 242
Cdd:COG0542    181 VIGRDEEIRRVIQILS-----------RRTKNN--------------PVL----IGepGVGKTAivegLAQRIvngdvpe 231
                           90
                   ....*....|...
gi 1002243632  243 -LHDPRVIShFDM 254
Cdd:COG0542    232 sLKDKRVLS-LDL 243
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
635-698 8.32e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 43.38  E-value: 8.32e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002243632  635 KELPASIGKLKHLRYLKISGdCPFKSLPqEFCHLYNLQIFSATKCRLENLPSDFNkLRNLRRFD 698
Cdd:COG4886    218 TDLPEPLANLTNLETLDLSN-NQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLD 278
Rx_N pfam18052
Rx N-terminal domain; This entry represents the N-terminal domain found in many plant ...
53-101 2.96e-03

Rx N-terminal domain; This entry represents the N-terminal domain found in many plant resistance proteins. This domain has been predicted to be a coiled-coil, however the structure shows that it adopts a four helical bundle fold.


Pssm-ID: 436239  Cd Length: 93  Bit Score: 38.02  E-value: 2.96e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1002243632   53 LQCLRDTLPAKYDLIDRAEWRSH-ERRVAELLPNLKDAMYNADDLLDEFR 101
Cdd:pfam18052   27 LEKLKDELESIQAFLEDAERKQItDEQVKLWLKQLRDVAYDAEDVLDEFL 76
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
786-999 8.17e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.92  E-value: 8.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  786 TSLSYLNLTGCPGEFLPTWFhpSNLPMLTSLELIACHdfVTiptpsmsqsidpnEIPKVLTEnnkgrpgiFSSLNHVIIe 865
Cdd:COG4886    113 TNLESLDLSGNQLTDLPEEL--ANLTNLKELDLSNNQ--LT-------------DLPEPLGN--------LTNLKSLDL- 166
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002243632  866 SCNKLSNLDQFLqpAYLPAIKTIKITKCrQLVELPTDrLGEFHFLEELEVSHCpNLNDpQSLSIPTLKKLKLIN-SWNLL 944
Cdd:COG4886    167 SNNQLTDLPEEL--GNLTNLKELDLSNN-QITDLPEP-LGNLTNLEELDLSGN-QLTD-LPEPLANLTNLETLDlSNNQL 240
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1002243632  945 gdieccsltslvfslwhvTSIPlhvWSSSFPALQKLQIADSGITGESQSSVLTSL 999
Cdd:COG4886    241 ------------------TDLP---ELGNLTNLEELDLSNNQLTDLPPLANLTNL 274
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH