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Conserved domains on  [gi|767935796|ref|XP_011541657|]
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dimethylglycine dehydrogenase, mitochondrial isoform X2 [Homo sapiens]

Protein Classification

FAD-dependent oxidoreductase( domain architecture ID 11429831)

FAD-dependent oxidoreductase containing a GcvT (glycine cleavage system T) domain such as sarcosine dehydrogenase and dimethylglycine dehydrogenase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
49-431 8.19e-89

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 283.33  E-value: 8.19e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAGSTWHAAGL--TTYFHPGIN-LKKIHYDSIKLYEKLEEETGQ 125
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQlrPGLAALADRaLVRLAREALDLWRELAAELGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 126 VVGFHQPGSIRLATTPVRVDEFKY---QMTRTGWHATeqyLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMAL 202
Cdd:COG0665   81 DCDFRRTGVLYLARTEAELAALRAeaeALRALGLPVE---LLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRAL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 203 AAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTstisEVK 282
Cdd:COG0665  158 ARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVT----EPL 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 283 ALKRELPVLRDleGSYYLRQERDG-LLFGPYESqekmkvqdswvtngvppgFGKELFESDLDRIMEHIKAAMEMVPVLKK 361
Cdd:COG0665  234 PDLPLRPVLDD--TGVYLRPTADGrLLVGGTAE------------------PAGFDRAPTPERLEALLRRLRRLFPALAD 293

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767935796 362 ADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 431
Cdd:COG0665  294 AEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHgGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 465-750 8.35e-77

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


:

Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 251.92  E-value: 8.35e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 465 GRPTQRvSGLYQRLESK-CSMGFHAGWEQPHWFYkpgqdtqyrpsfrrtnwfEPVGSEYKQVMQRVAVTDLSPFGKFNIK 543
Cdd:COG0404    1 FRPLRR-TPLHDRHVALgAKFVDFGGWEMPVQYP------------------GGVIAEHLAVREAVGLFDVSHMGKIEVT 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 544 GQDSIRLLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEeAVKGGYDVEIK 621
Cdd:COG0404   62 GPDAAAFLDRLVTNDVSKlkPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEE-HLPPDFDVTIT 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 622 NITDELGVLGVAGPQARKVLQKLTSEDLSDdvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNA 701
Cdd:COG0404  141 DVTDDWALLAVQGPKAREVLAKLTDADLSA--LPFMSFREGTVAGVPVRVSRTGYTGEDGFEIYVPAEDAEALWDALLEA 218

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 767935796 702 GQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNK 750
Cdd:COG0404  219 GEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDK 267
FAO_M pfam16350
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ...
 417-472 1.25e-15

FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).


:

Pssm-ID: 465100  Cd Length: 56  Bit Score: 71.33  E-value: 1.25e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767935796  417 HGEPPFDLIELDPNRYGK-WTTTQYTEAKARESYGFNNIVGYPKEERFAGRPtQRVS 472
Cdd:pfam16350   1 DGEPPIDLWECDIRRFGPhQNNREYLRERVAENYGEVYDIHHPNEEREAGRP-LRTS 56
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
49-431 8.19e-89

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 283.33  E-value: 8.19e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAGSTWHAAGL--TTYFHPGIN-LKKIHYDSIKLYEKLEEETGQ 125
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQlrPGLAALADRaLVRLAREALDLWRELAAELGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 126 VVGFHQPGSIRLATTPVRVDEFKY---QMTRTGWHATeqyLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMAL 202
Cdd:COG0665   81 DCDFRRTGVLYLARTEAELAALRAeaeALRALGLPVE---LLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRAL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 203 AAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTstisEVK 282
Cdd:COG0665  158 ARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVT----EPL 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 283 ALKRELPVLRDleGSYYLRQERDG-LLFGPYESqekmkvqdswvtngvppgFGKELFESDLDRIMEHIKAAMEMVPVLKK 361
Cdd:COG0665  234 PDLPLRPVLDD--TGVYLRPTADGrLLVGGTAE------------------PAGFDRAPTPERLEALLRRLRRLFPALAD 293

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767935796 362 ADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 431
Cdd:COG0665  294 AEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHgGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 465-750 8.35e-77

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 251.92  E-value: 8.35e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 465 GRPTQRvSGLYQRLESK-CSMGFHAGWEQPHWFYkpgqdtqyrpsfrrtnwfEPVGSEYKQVMQRVAVTDLSPFGKFNIK 543
Cdd:COG0404    1 FRPLRR-TPLHDRHVALgAKFVDFGGWEMPVQYP------------------GGVIAEHLAVREAVGLFDVSHMGKIEVT 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 544 GQDSIRLLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEeAVKGGYDVEIK 621
Cdd:COG0404   62 GPDAAAFLDRLVTNDVSKlkPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEE-HLPPDFDVTIT 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 622 NITDELGVLGVAGPQARKVLQKLTSEDLSDdvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNA 701
Cdd:COG0404  141 DVTDDWALLAVQGPKAREVLAKLTDADLSA--LPFMSFREGTVAGVPVRVSRTGYTGEDGFEIYVPAEDAEALWDALLEA 218

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 767935796 702 GQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNK 750
Cdd:COG0404  219 GEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDK 267
GCV_T pfam01571
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ...
 488-745 1.07e-69

Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.


Pssm-ID: 460255  Cd Length: 254  Bit Score: 229.01  E-value: 1.07e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  488 AGWEQPHWFYKPGQDtqyrpsfrrtnwfepvgSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVI--PKVGFT 565
Cdd:pfam01571  15 AGWEMPVQYGSNGIL-----------------AEHRAVREAAGLFDVSHMGKIEVSGPDAAAFLQRLTTNDVskLKPGRA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  566 NISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGgyDVEIKNITDELGVLGVAGPQARKVLQKLT 645
Cdd:pfam01571  78 TYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHAEKL--DVVVVDVTDDYALLALQGPKAREVLEKLT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  646 SEDLSDDvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFR 725
Cdd:pfam01571 156 DGDLLEA-LPFFSFREIEIGGVPVRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELGLRPAGLGARDSLRLEAGLP 234

                         250       260
                  ....*....|....*....|
gi 767935796  726 AWGLEMNCDTNPLEAGLEYF 745
Cdd:pfam01571 235 LYGHDLDEETTPLEAGLGWA 254
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 53-414 5.66e-63

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 214.18  E-value: 5.66e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796   53 VIIGGGCVGVSLAYHLAKAGMkDVVLLEK-SELTAGSTWHAAGLttyFHPGI------NLKKIHYDSIKLYEKLEEETGQ 125
Cdd:pfam01266   3 VVIGGGIVGLSTAYELARRGL-SVTLLERgDDPGSGASGRNAGL---IHPGLrylepsELARLALEALDLWEELEEELGI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  126 VVGFHQPGSIRLATTPV--RVDEFKYQMTRTGWHAteqYLIEPEKIQEMFPLLnmNKVLAGLYNPGDGHIDPYSLTMALA 203
Cdd:pfam01266  79 DCGFRRCGVLVLARDEEeeALEKLLAALRRLGVPA---ELLDAEELRELEPLL--PGLRGGLFYPDGGHVDPARLLRALA 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  204 AGARKCGALLKYPAPVTSLKaRSDGTWDVETPqGSMRAnrIVNAAGFWAREVGkMIGLEHPLIPVQHQYVVTSTISEvKA 283
Cdd:pfam01266 154 RAAEALGVRIIEGTEVTGIE-EEGGVWGVVTT-GEADA--VVNAAGAWADLLA-LPGLRLPVRPVRGQVLVLEPLPE-AL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  284 LKRELPVLRDLEGSYYLRQERDG-LLFGPYEsqekmkvqdswvtngvpPGFGKELFESDLDRIMEHIKAAMEMVPVLkkA 362
Cdd:pfam01266 228 LILPVPITVDPGRGVYLRPRADGrLLLGGTD-----------------EEDGFDDPTPDPEEIEELLEAARRLFPAL--A 288

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767935796  363 DIINVVNGPITYsPDILPMVGPHqGVRNYWVAIGF-GYGIIHAGGVGKYLSDW 414
Cdd:pfam01266 289 DIERAWAGLRPL-PDGLPIIGRP-GSPGLYLATGHgGHGLTLAPGIGKLLAEL 339
gcvT PRK00389
glycine cleavage system aminomethyltransferase GcvT;
474-750 8.02e-36

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 234742 [Multi-domain]  Cd Length: 359  Bit Score: 139.10  E-value: 8.02e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 474 LYQR-LESKCSMGFHAGWEQPHWFykpgqdtqyrpsfrrtnwfepvGS---EYKQVMQRVAVTDLSPFGKFNIKGQDSIR 549
Cdd:PRK00389   7 LYDLhVALGAKMVDFGGWEMPVQY----------------------GSiieEHHAVRTDAGLFDVSHMGEVDVTGPDALA 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 550 LLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAvkGGYDVEIKNITDEL 627
Cdd:PRK00389  65 FLQYLLANDVSKlkPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVVNAANREKDLAWIKSHA--AGFGVEVTDRSDDL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 628 GVLGVAGPQARKVLQKLTSEDLSD-DVFKFLQTKSLKVSNipvtaIRIS---YTGELGWELYHRREDSVALYDAIMNAgq 703
Cdd:PRK00389 143 AMIAVQGPKAREKLQKLTDADLSElKPFFGAQGAEVGGGD-----VLVArtgYTGEDGFEIYLPAEDAEALWDALLEA-- 215

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 767935796 704 eeGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNK 750
Cdd:PRK00389 216 --GVKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEE 260
FAO_M pfam16350
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ...
 417-472 1.25e-15

FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).


Pssm-ID: 465100  Cd Length: 56  Bit Score: 71.33  E-value: 1.25e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767935796  417 HGEPPFDLIELDPNRYGK-WTTTQYTEAKARESYGFNNIVGYPKEERFAGRPtQRVS 472
Cdd:pfam16350   1 DGEPPIDLWECDIRRFGPhQNNREYLRERVAENYGEVYDIHHPNEEREAGRP-LRTS 56
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 51-434 2.15e-11

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 66.39  E-value: 2.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796   51 ETVIIGGGCVGVSLAYHLAKAGMKdVVLLEKSEL--TAGS------TWHAAGLTTYFHPginlkkIHYDSIKLYEKLEEE 122
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKK-TLLLEQFDLphSRGSshgqsrIIRKAYPEDFYTP------MMLECYQLWAQLEKE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  123 TGQVVgFHQPGSIRLAttPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMAL 202
Cdd:TIGR01377  75 AGTKL-HRQTGLLLLG--PKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRAL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  203 AAGARKCGALLKYPAPVTSLKaRSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQhQYVVTSTISEVK 282
Cdd:TIGR01377 152 QELAEAHGATVRDGTKVVEIE-PTELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLR-INVCYWREKEPG 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  283 ALK--RELPVL--RDLEGSYYlrqerdGLLFGPYESQEKMKVQ-DSWV---TNGVPPGFGKElfesDLDRIMEHIKAAM- 353
Cdd:TIGR01377 230 SYGvsQAFPCFlvLGLNPHIY------GLPSFEYPGLMKVYYHhGQQIdpdERDCPFGADIE----DVQILRKFVRDHLp 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  354 EMVPVLKKADIINVVNgpitySPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 432
Cdd:TIGR01377 300 GLNGEPKKGEVCMYTN-----TPDEHFVIDLHPKYDNVVIGAGFsGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRF 374


                  ..
gi 767935796  433 GK 434
Cdd:TIGR01377 375 AL 376
solA PRK11259
N-methyl-L-tryptophan oxidase;
53-431 7.88e-11

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 64.47  E-value: 7.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  53 VIIGGGCVGVSLAYHLAKAGmKDVVLLEKSEL--TAGS-------TWHAaglttYF-HPGinlkkihY-----DSIKLYE 117
Cdd:PRK11259   7 IVIGLGSMGSAAGYYLARRG-LRVLGLDRFMPphQQGSshgdtriIRHA-----YGeGPA-------YvplvlRAQELWR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 118 KLEEETGQVVgFHQPGSIRLAttpVRVDEFkyqmTRTGWHATEQY-----LIEPEKIQEMFPLLNMNKVLAGLYNPGDGH 192
Cdd:PRK11259  74 ELERESGEPL-FVRTGVLNLG---PADSDF----LANSIRSARQHglpheVLDAAEIRRRFPQFRLPDGYIALFEPDGGF 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 193 IDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTwDVETPQGSMRANRIVNAAGFWAREvgkMIG-LEHPLIP---V 268
Cdd:PRK11259 146 LRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGV-TVTTADGTYEAKKLVVSAGAWVKD---LLPpLELPLTPvrqV 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 269 QHQYVVTSTISEvkalKRELPVlrdlegsyYLRQERDGLLF-G-PYESQEKMKVqdswvtngvppgfGKELF------ES 340
Cdd:PRK11259 222 LAWFQADGRYSE----PNRFPA--------FIWEVPDGDQYyGfPAENGPGLKI-------------GKHNGgqeitsPD 276

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 341 DLDRIMEHIKAAMEMVPVLKK--ADIINVVNGPI---TYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDW 414
Cdd:PRK11259 277 ERDRFVTVAEDGAELRPFLRNylPGVGPCLRGAActyTNTPDEHFIIDTLPGHPNVLVASGCsGHGFKFASVLGEILADL 356

                        410
                 ....*....|....*..
gi 767935796 415 ILHGEPPFDLIELDPNR 431
Cdd:PRK11259 357 AQDGTSDFDLSPFSLSR 373
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
49-431 8.19e-89

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 283.33  E-value: 8.19e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAGSTWHAAGL--TTYFHPGIN-LKKIHYDSIKLYEKLEEETGQ 125
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRPGSGASGRNAGQlrPGLAALADRaLVRLAREALDLWRELAAELGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 126 VVGFHQPGSIRLATTPVRVDEFKY---QMTRTGWHATeqyLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMAL 202
Cdd:COG0665   81 DCDFRRTGVLYLARTEAELAALRAeaeALRALGLPVE---LLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRAL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 203 AAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTstisEVK 282
Cdd:COG0665  158 ARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVT----EPL 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 283 ALKRELPVLRDleGSYYLRQERDG-LLFGPYESqekmkvqdswvtngvppgFGKELFESDLDRIMEHIKAAMEMVPVLKK 361
Cdd:COG0665  234 PDLPLRPVLDD--TGVYLRPTADGrLLVGGTAE------------------PAGFDRAPTPERLEALLRRLRRLFPALAD 293

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767935796 362 ADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 431
Cdd:COG0665  294 AEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHgGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
GcvT COG0404
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ...
 465-750 8.35e-77

Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage


Pssm-ID: 440173 [Multi-domain]  Cd Length: 372  Bit Score: 251.92  E-value: 8.35e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 465 GRPTQRvSGLYQRLESK-CSMGFHAGWEQPHWFYkpgqdtqyrpsfrrtnwfEPVGSEYKQVMQRVAVTDLSPFGKFNIK 543
Cdd:COG0404    1 FRPLRR-TPLHDRHVALgAKFVDFGGWEMPVQYP------------------GGVIAEHLAVREAVGLFDVSHMGKIEVT 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 544 GQDSIRLLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEeAVKGGYDVEIK 621
Cdd:COG0404   62 GPDAAAFLDRLVTNDVSKlkPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEE-HLPPDFDVTIT 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 622 NITDELGVLGVAGPQARKVLQKLTSEDLSDdvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNA 701
Cdd:COG0404  141 DVTDDWALLAVQGPKAREVLAKLTDADLSA--LPFMSFREGTVAGVPVRVSRTGYTGEDGFEIYVPAEDAEALWDALLEA 218

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 767935796 702 GQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNK 750
Cdd:COG0404  219 GEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDK 267
GCV_T pfam01571
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ...
 488-745 1.07e-69

Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.


Pssm-ID: 460255  Cd Length: 254  Bit Score: 229.01  E-value: 1.07e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  488 AGWEQPHWFYKPGQDtqyrpsfrrtnwfepvgSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVI--PKVGFT 565
Cdd:pfam01571  15 AGWEMPVQYGSNGIL-----------------AEHRAVREAAGLFDVSHMGKIEVSGPDAAAFLQRLTTNDVskLKPGRA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  566 NISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGgyDVEIKNITDELGVLGVAGPQARKVLQKLT 645
Cdd:pfam01571  78 TYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHAEKL--DVVVVDVTDDYALLALQGPKAREVLEKLT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  646 SEDLSDDvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFR 725
Cdd:pfam01571 156 DGDLLEA-LPFFSFREIEIGGVPVRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELGLRPAGLGARDSLRLEAGLP 234

                         250       260
                  ....*....|....*....|
gi 767935796  726 AWGLEMNCDTNPLEAGLEYF 745
Cdd:pfam01571 235 LYGHDLDEETTPLEAGLGWA 254
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 53-414 5.66e-63

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 214.18  E-value: 5.66e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796   53 VIIGGGCVGVSLAYHLAKAGMkDVVLLEK-SELTAGSTWHAAGLttyFHPGI------NLKKIHYDSIKLYEKLEEETGQ 125
Cdd:pfam01266   3 VVIGGGIVGLSTAYELARRGL-SVTLLERgDDPGSGASGRNAGL---IHPGLrylepsELARLALEALDLWEELEEELGI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  126 VVGFHQPGSIRLATTPV--RVDEFKYQMTRTGWHAteqYLIEPEKIQEMFPLLnmNKVLAGLYNPGDGHIDPYSLTMALA 203
Cdd:pfam01266  79 DCGFRRCGVLVLARDEEeeALEKLLAALRRLGVPA---ELLDAEELRELEPLL--PGLRGGLFYPDGGHVDPARLLRALA 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  204 AGARKCGALLKYPAPVTSLKaRSDGTWDVETPqGSMRAnrIVNAAGFWAREVGkMIGLEHPLIPVQHQYVVTSTISEvKA 283
Cdd:pfam01266 154 RAAEALGVRIIEGTEVTGIE-EEGGVWGVVTT-GEADA--VVNAAGAWADLLA-LPGLRLPVRPVRGQVLVLEPLPE-AL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  284 LKRELPVLRDLEGSYYLRQERDG-LLFGPYEsqekmkvqdswvtngvpPGFGKELFESDLDRIMEHIKAAMEMVPVLkkA 362
Cdd:pfam01266 228 LILPVPITVDPGRGVYLRPRADGrLLLGGTD-----------------EEDGFDDPTPDPEEIEELLEAARRLFPAL--A 288

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 767935796  363 DIINVVNGPITYsPDILPMVGPHqGVRNYWVAIGF-GYGIIHAGGVGKYLSDW 414
Cdd:pfam01266 289 DIERAWAGLRPL-PDGLPIIGRP-GSPGLYLATGHgGHGLTLAPGIGKLLAEL 339
gcvT PRK00389
glycine cleavage system aminomethyltransferase GcvT;
474-750 8.02e-36

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 234742 [Multi-domain]  Cd Length: 359  Bit Score: 139.10  E-value: 8.02e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 474 LYQR-LESKCSMGFHAGWEQPHWFykpgqdtqyrpsfrrtnwfepvGS---EYKQVMQRVAVTDLSPFGKFNIKGQDSIR 549
Cdd:PRK00389   7 LYDLhVALGAKMVDFGGWEMPVQY----------------------GSiieEHHAVRTDAGLFDVSHMGEVDVTGPDALA 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 550 LLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAvkGGYDVEIKNITDEL 627
Cdd:PRK00389  65 FLQYLLANDVSKlkPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVVNAANREKDLAWIKSHA--AGFGVEVTDRSDDL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 628 GVLGVAGPQARKVLQKLTSEDLSD-DVFKFLQTKSLKVSNipvtaIRIS---YTGELGWELYHRREDSVALYDAIMNAgq 703
Cdd:PRK00389 143 AMIAVQGPKAREKLQKLTDADLSElKPFFGAQGAEVGGGD-----VLVArtgYTGEDGFEIYLPAEDAEALWDALLEA-- 215

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 767935796 704 eeGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNK 750
Cdd:PRK00389 216 --GVKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEE 260
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
48-365 4.24e-33

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 132.58  E-value: 4.24e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEK-SELTAGSTWHAAGLttyFHPGINLKKihyDSIK---------LYE 117
Cdd:COG0579    3 EMYDVVIIGAGIVGLALARELSRYEDLKVLVLEKeDDVAQESSGNNSGV---IHAGLYYTP---GSLKarlcvegneLFY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 118 KLEEETGqvVGFHQPGSIRLATTPvrvDEFKY------QMTRTGWHATEqyLIEPEKIQEMFPLLNmNKVLAGLYNPGDG 191
Cdd:COG0579   77 ELCRELG--IPFKRCGKLVVATGE---EEVAFleklyeRGKANGVPGLE--ILDREELRELEPLLS-DEGVAALYSPSTG 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 192 HIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGtWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHP--LIPVQ 269
Cdd:COG0579  149 IVDPGALTRALAENAEANGVELLLNTEVTGIEREGDG-WEVTTNGGTIRARFVINAAGLYADRLAQMAGIGKDfgIFPVK 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 270 HQYVVTS-TISEVKAL-----KRELP-----VLRDLEGSyylrqerdgLLFGPYeSQEKMKVQDSW---VTNGVPPGFGK 335
Cdd:COG0579  228 GEYLVLDkPAELVNAKvypvpDPGAPflgvhLTRTIDGN---------LLFGPN-AVFVPKKEDSLldlFESLRFPNFWP 297

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 767935796 336 ELFESDLDRIMEH---------IKAAMEMVPVLKKADII 365
Cdd:COG0579  298 MLAKNLLTKYLESvtslskeafLEALRKYVPELPDEDLI 336
PLN02319 PLN02319
aminomethyltransferase
 488-742 1.46e-17

aminomethyltransferase


Pssm-ID: 177953 [Multi-domain]  Cd Length: 404  Bit Score: 85.55  E-value: 1.46e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 488 AGWEQPhwfykpgqdTQYRPS-FRRTNWFEPVGSEYkqvmqrvavtDLSPFGKFNIKGQDSIRLLDHLFANVIP--KVGF 564
Cdd:PLN02319  52 AGWSMP---------IQYKDSiMDSTLNCRQNGSLF----------DVSHMCGLSLKGKDAIPFLETLVVADIAglKDGT 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 565 TNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEE--EAVKG-GYDVEIkNITDELGVLGVAGPQARKVL 641
Cdd:PLN02319 113 GTLSVFTNEKGGIIDDTVITKVTDDHIYLVVNAGCRDKDLAHIEEhmKAFKAkGGDVSW-HVHDERSLLALQGPLAAPVL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 642 QKLTSEDLSDdvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMnAGQEEGIDNFGTYAMNALRLE 721
Cdd:PLN02319 192 QHLTKEDLSK--MYFGDFRITDINGADCFLTRTGYTGEDGFEISVPSEHAVDLAKALL-EKSEGKVRLTGLGARDSLRLE 268

                        250       260
                 ....*....|....*....|.
gi 767935796 722 KAFRAWGLEMNCDTNPLEAGL 742
Cdd:PLN02319 269 AGLCLYGNDLEEHITPVEAGL 289
FAO_M pfam16350
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ...
 417-472 1.25e-15

FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).


Pssm-ID: 465100  Cd Length: 56  Bit Score: 71.33  E-value: 1.25e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767935796  417 HGEPPFDLIELDPNRYGK-WTTTQYTEAKARESYGFNNIVGYPKEERFAGRPtQRVS 472
Cdd:pfam16350   1 DGEPPIDLWECDIRRFGPhQNNREYLRERVAENYGEVYDIHHPNEEREAGRP-LRTS 56
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 51-434 2.15e-11

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 66.39  E-value: 2.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796   51 ETVIIGGGCVGVSLAYHLAKAGMKdVVLLEKSEL--TAGS------TWHAAGLTTYFHPginlkkIHYDSIKLYEKLEEE 122
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKK-TLLLEQFDLphSRGSshgqsrIIRKAYPEDFYTP------MMLECYQLWAQLEKE 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  123 TGQVVgFHQPGSIRLAttPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMAL 202
Cdd:TIGR01377  75 AGTKL-HRQTGLLLLG--PKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRAL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  203 AAGARKCGALLKYPAPVTSLKaRSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQhQYVVTSTISEVK 282
Cdd:TIGR01377 152 QELAEAHGATVRDGTKVVEIE-PTELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLR-INVCYWREKEPG 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  283 ALK--RELPVL--RDLEGSYYlrqerdGLLFGPYESQEKMKVQ-DSWV---TNGVPPGFGKElfesDLDRIMEHIKAAM- 353
Cdd:TIGR01377 230 SYGvsQAFPCFlvLGLNPHIY------GLPSFEYPGLMKVYYHhGQQIdpdERDCPFGADIE----DVQILRKFVRDHLp 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  354 EMVPVLKKADIINVVNgpitySPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 432
Cdd:TIGR01377 300 GLNGEPKKGEVCMYTN-----TPDEHFVIDLHPKYDNVVIGAGFsGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRF 374


                  ..
gi 767935796  433 GK 434
Cdd:TIGR01377 375 AL 376
solA PRK11259
N-methyl-L-tryptophan oxidase;
53-431 7.88e-11

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 64.47  E-value: 7.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  53 VIIGGGCVGVSLAYHLAKAGmKDVVLLEKSEL--TAGS-------TWHAaglttYF-HPGinlkkihY-----DSIKLYE 117
Cdd:PRK11259   7 IVIGLGSMGSAAGYYLARRG-LRVLGLDRFMPphQQGSshgdtriIRHA-----YGeGPA-------YvplvlRAQELWR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 118 KLEEETGQVVgFHQPGSIRLAttpVRVDEFkyqmTRTGWHATEQY-----LIEPEKIQEMFPLLNMNKVLAGLYNPGDGH 192
Cdd:PRK11259  74 ELERESGEPL-FVRTGVLNLG---PADSDF----LANSIRSARQHglpheVLDAAEIRRRFPQFRLPDGYIALFEPDGGF 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 193 IDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTwDVETPQGSMRANRIVNAAGFWAREvgkMIG-LEHPLIP---V 268
Cdd:PRK11259 146 LRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGV-TVTTADGTYEAKKLVVSAGAWVKD---LLPpLELPLTPvrqV 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 269 QHQYVVTSTISEvkalKRELPVlrdlegsyYLRQERDGLLF-G-PYESQEKMKVqdswvtngvppgfGKELF------ES 340
Cdd:PRK11259 222 LAWFQADGRYSE----PNRFPA--------FIWEVPDGDQYyGfPAENGPGLKI-------------GKHNGgqeitsPD 276

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 341 DLDRIMEHIKAAMEMVPVLKK--ADIINVVNGPI---TYSPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDW 414
Cdd:PRK11259 277 ERDRFVTVAEDGAELRPFLRNylPGVGPCLRGAActyTNTPDEHFIIDTLPGHPNVLVASGCsGHGFKFASVLGEILADL 356

                        410
                 ....*....|....*..
gi 767935796 415 ILHGEPPFDLIELDPNR 431
Cdd:PRK11259 357 AQDGTSDFDLSPFSLSR 373
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
53-262 1.42e-09

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 60.61  E-value: 1.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  53 VIIGGGCVGVSLAYHLAKA--GMKdVVLLEK-SELTAGSTWHA-----AGLttYFHPGiNLK------------------ 106
Cdd:PRK11728   6 VIIGGGIVGLSTAMQLQERypGAR-IAVLEKeSGPARHQTGHNsgvihAGV--YYTPG-SLKarfcrrgneatkafcdqh 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 107 KIHYdsiklyekleEETGQVVgfhqpgsirLATTPVRVDEFK--YQMTRTgwHATEQYLIEPEKIQEMFPllNMNKvLAG 184
Cdd:PRK11728  82 GIPY----------EECGKLL---------VATSELELERMEalYERARA--NGIEVERLDAEELREREP--NIRG-LGA 137

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767935796 185 LYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTwDVETPQGSMRANRIVNAAGFWAREVGKMIGLE 262
Cdd:PRK11728 138 IFVPSTGIVDYRAVAEAMAELIQARGGEIRLGAEVTALDEHANGV-VVRTTQGEYEARTLINCAGLMSDRLAKMAGLE 214
gcvT PRK13579
glycine cleavage system aminomethyltransferase GcvT;
533-744 8.11e-08

glycine cleavage system aminomethyltransferase GcvT;


Pssm-ID: 237435 [Multi-domain]  Cd Length: 370  Bit Score: 54.95  E-value: 8.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 533 DLSPFGKFNIKGQDSIRLLDHLFAN--VIPKVGFTNISHMLTPKGRVYAELTVSHQSpGEFLLITGSGSELHDLRWIEEE 610
Cdd:PRK13579  56 DVSHMGQIEVSGKDAAAALERLVPVdiLALKEGRQRYTFFTNEQGGILDDLMVTNLG-DHLFLVVNAACKDADIAHLREH 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 611 AVKggyDVEIKNITDElGVLGVAGPQARKVLQKLTSeDLSDdvFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRRED 690
Cdd:PRK13579 135 LSD---ECEVNPLDDR-ALLALQGPEAEAVLADLGP-PVAA--LRFMDGFEPRLHGVDCFVSRSGYTGEDGFEISVPADA 207

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767935796 691 SVALYDAIMNAGQEEGIdnfGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEY 744
Cdd:PRK13579 208 AEALAEALLADPRVEPI---GLGARDSLRLEAGLCLYGHDIDTTTTPVEAALEW 258
dmdA PRK12486
dimethylsulfoniopropionate demethylase;
515-748 3.36e-07

dimethylsulfoniopropionate demethylase;


Pssm-ID: 237113 [Multi-domain]  Cd Length: 368  Bit Score: 53.22  E-value: 3.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 515 FEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLdhlfanvipkvgftnisHMLTPK-------GRVYAELTVSHQS 587
Cdd:PRK12486  40 FESVEDDYAHLKEHVQVWDVAVERQVEIRGPDAARLV-----------------QMLTPRdlrgmkpGQCYYVPIVDETG 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 588 -----PGEFLL------ITGSGSELhdLRWIEEEAVKGGYDVEIknitDELGV--LGVAGPQARKVLQKLTSEDLSDdvF 654
Cdd:PRK12486 103 gmlndPVALKLaedrwwISIADSDL--LLWVKGLANGRKLDVLV----VEPDVspLAVQGPKADALMARVFGEAIRD--L 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 655 KFLQTKSLKVSNIPVTAIRISYTGELGWELY-HRREDSVALYDAIMNAGQEEgidNFGTYAMNAL-RLEKAFRAWGLEMN 732
Cdd:PRK12486 175 RFFRFGYFDFEGTDLVIARSGYSKQGGFEIYvEGSDLGMPLWDALFEAGKDL---NVRAGCPNLIeRIEGGLLSYGNDMT 251

                        250
                 ....*....|....*.
gi 767935796 733 CDTNPLEAGLEYFVKL 748
Cdd:PRK12486 252 RDNTPHECGLGRFCNT 267
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 35-432 1.51e-06

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 51.77  E-value: 1.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  35 EEKPPLSAETQWKDRA------ETVIIGGGCVGVSLAYHLAKAGmKDVVLLEK-SELTAGSTWHAAGLttyFHPGINLKK 107
Cdd:PRK01747 240 EQTLPAPLAAPWFARPgspkarDAAIIGGGIAGAALALALARRG-WQVTLYEAdEAPAQGASGNRQGA---LYPLLSKDD 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 108 -----------IHydSIKLYEKLEEEtGQVVGFHQPGSIRLATTPVRVDEFKyQMTRTGWHATeqyLIEPEKIQEMFPLL 176
Cdd:PRK01747 316 nalsrffraafLF--ARRFYDALPAA-GVAFDHDWCGVLQLAWDEKSAEKIA-KMLALGLPAE---LARALDAEEAEELA 388

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 177 NMNKVLAGLYNPGDGHIDPYSLTMALAAGArKCGALLKYPAPVTSLkARSDGTWDVETPQGSMRANRIVNAAGfwAREVG 256
Cdd:PRK01747 389 GLPVPCGGIFYPQGGWLCPAELCRALLALA-GQQLTIHFGHEVARL-EREDDGWQLDFAGGTLASAPVVVLAN--GHDAA 464

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 257 KMIGLEH-PLIPVQHQyvVTS--TISEVKALKREL-------PVLRD---LEGSYYLRQERDgLLFGPYESQEkmkvqds 323
Cdd:PRK01747 465 RFAQTAHlPLYSVRGQ--VSHlpTTPALSALKQVLcydgyltPQPANgthCIGASYDRDDTD-TAFREADHQE------- 534

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 324 wvtngvppgfgkelfesDLDRImehikaaMEMVPVLKKADIINVVN-----GPITYSPDILPMVGP----HQGVRNY--- 391
Cdd:PRK01747 535 -----------------NLERL-------AECLPQALWAKEVDVSAlqgrvGFRCASRDRLPMVGNvpdeAATLAEYaal 590

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767935796 392 ---------------WVAIGFG-YGIIHAGGVGKYLSDWILhGEP---PFDLIE-LDPNRY 432
Cdd:PRK01747 591 anqqpardaprlpglYVAGALGsRGLCSAPLGAELLASQIE-GEPlplERDLLAaLHPNRF 650
SoxG COG4583
Sarcosine oxidase gamma subunit [Amino acid transport and metabolism];
587-704 2.11e-06

Sarcosine oxidase gamma subunit [Amino acid transport and metabolism];


Pssm-ID: 443640  Cd Length: 169  Bit Score: 48.32  E-value: 2.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 587 SPGEFLLItGSGSELHDLRWIEEEAVKGGY----DVeikniTDELGVLGVAGPQARKVLQKLTSEDLSDDVFK---FLQT 659
Cdd:COG4583   54 GPDEWLLL-APYGAAEDLAAALAAALAGLHaavvDV-----SDGRTVFELSGPRARDVLAKLCPLDLHPRAFPvgaAART 127

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 767935796 660 kslKVSNIPVTAIRisyTGELGWELYHRRedSVA--LYDAIMNAGQE 704
Cdd:COG4583  128 ---VLAHVGVVLWR---TGEDRFRLLVRR--SFAdyLWHWLEDAARE 166
PRK00711 PRK00711
D-amino acid dehydrogenase;
53-432 2.22e-06

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 50.57  E-value: 2.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  53 VIIGGGCVGVSLAYHLAKAGMKDVVL-------LEKSELTAG-------STWHAaglttyfhPGINLKKI---------- 108
Cdd:PRK00711   4 VVLGSGVIGVTSAWYLAQAGHEVTVIdrqpgpaLETSFANAGqispgyaAPWAA--------PGVPLKAIkwlfqrhapl 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 109 ------------------------HYD------------SIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVD----EFK 148
Cdd:PRK00711  76 airpdgdpfqlrwmwqmlrnctasRYAvnksrmvrlaeySRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDaaakDIA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 149 YQmTRTGwhaTEQYLIEPEKIQEMFPLLN--MNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARS 226
Cdd:PRK00711 156 VL-EEAG---VPYELLDRDELAAVEPALAgvRHKLVGGLRLPNDETGDCQLFTQRLAAMAEQLGVKFRFNTPVDGLLVEG 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 227 DGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQhQYVVT-----------STI--SEVK-ALKRELPVLR 292
Cdd:PRK00711 232 GRITGVQTGGGVITADAYVVALGSYSTALLKPLGVDIPVYPLK-GYSLTvpitdedrapvSTVldETYKiAITRFDDRIR 310

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 293 -----DLEG-SYYLRQERDGLLfgpyesqeKMKVQDswvtngvppgfgkeLFESDLDrimehikaamemvpvLKKADIIn 366
Cdd:PRK00711 311 vggmaEIVGfDLRLDPARRETL--------EMVVRD--------------LFPGGGD---------------LSQATFW- 352

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767935796 367 vvNG--PITysPDILPMVGPHQgVRNYWVAIGFG-YGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 432
Cdd:PRK00711 353 --TGlrPMT--PDGTPIVGATR-YKNLWLNTGHGtLGWTMACGSGQLLADLISGRKPAIDADDLSVARY 416
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 46-94 1.86e-05

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 47.79  E-value: 1.86e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 767935796  46 WKDRAETVIIGGGCVGVSLAYHLAKAGmkDVVLLEKSELTAGSTWHAAG 94
Cdd:COG0029    1 ERLKTDVLVIGSGIAGLSAALKLAERG--RVTLLTKGELGESNTRWAQG 47
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 51-91 5.76e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 46.01  E-value: 5.76e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 767935796  51 ETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSElTAGSTWH 91
Cdd:COG2072    8 DVVVIGAGQAGLAAAYHLRRAGI-DFVVLEKAD-DVGGTWR 46
GlpA COG0578
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 166-264 1.16e-04

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440343 [Multi-domain]  Cd Length: 501  Bit Score: 45.51  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 166 PEKIQEMFPLLNMNKVLAG-LYnpGDGHIDPYSLTMALAAGARKCGAL-LKYpAPVTSLKARSDGTW-----DVET-PQG 237
Cdd:COG0578  107 RAEALALAPLLRPDGLRGGfEY--YDAQVDDARLVLELARTAAERGAVvLNY-TRVTGLLRDGGRVWgvtvrDRLTgEEF 183

                         90       100
                 ....*....|....*....|....*..
gi 767935796 238 SMRANRIVNAAGFWAREVGKMIGLEHP 264
Cdd:COG0578  184 TVRARVVVNATGPWVDELRALDGPKAP 210
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 160-260 1.62e-04

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 44.63  E-value: 1.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 160 EQYLIEPEKIQEMFPLLNmNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG-----TWDVET 234
Cdd:PRK12409 162 ERRAVTPEEMRAIEPTLT-GEYYGGYYTPSDSTGDIHKFTTGLAAACARLGVQFRYGQEVTSIKTDGGGvvltvQPSAEH 240

                         90       100
                 ....*....|....*....|....*.
gi 767935796 235 PQGSMRANRIVNAAGFWAREVGKMIG 260
Cdd:PRK12409 241 PSRTLEFDGVVVCAGVGSRALAAMLG 266
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 52-84 6.11e-04

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 42.69  E-value: 6.11e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 767935796   52 TVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSEL 84
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGL-RVLLLEKKSF 34
PRK07233 PRK07233
hypothetical protein; Provisional
 53-100 8.22e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 42.57  E-value: 8.22e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 767935796  53 VIIGGGCVGVSLAYHLAKAGmKDVVLLEKSELTAG--STWHAAGLT--TYFH 100
Cdd:PRK07233   3 AIVGGGIAGLAAAYRLAKRG-HEVTVFEADDQLGGlaASFEFGGLPieRFYH 53
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 49-83 8.42e-04

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 42.51  E-value: 8.42e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 767935796  49 RAETVIIGGGCVGVSLAYHLAKAGMkDVVLLEKSE 83
Cdd:COG1232    1 MKRVAVIGGGIAGLTAAYRLAKAGH-EVTVLEASD 34
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 53-295 1.43e-03

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 41.46  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796  53 VIIGGGCVGVSLAYHLAKAGMkDVVLLEKSELTAgstWHAAGLTtyfhpginlkkIHYDSIKLYEKLeeetgqvvGFHQp 132
Cdd:COG0654    7 LIVGGGPAGLALALALARAGI-RVTVVERAPPPR---PDGRGIA-----------LSPRSLELLRRL--------GLWD- 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 133 gsiRLATTPVRVDEFKYQMTRTGWHATEqyliepekiqemFPllnmnkvLAGLYNPGDGHIDPYSLTMALAAGARKCGAL 212
Cdd:COG0654   63 ---RLLARGAPIRGIRVRDGSDGRVLAR------------FD-------AAETGLPAGLVVPRADLERALLEAARALGVE 120

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767935796 213 LKYPAPVTSLKARSDGtWDVETPQGS-MRANRIVNAAGFWAReVGKMIGLEHPLIPVQHQYVVTSTISEVKA-LKRELPV 290
Cdd:COG0654  121 LRFGTEVTGLEQDADG-VTVTLADGRtLRADLVVGADGARSA-VRRLLGIGFTGRDYPQRALWAGVRTELRArLAAAGPR 198


                 ....*
gi 767935796 291 LRDLE 295
Cdd:COG0654  199 LGELL 203
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
54-101 4.20e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 36.36  E-value: 4.20e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767935796   54 IIGGGCVGVSLAYHLAKAGmKDVVLLEKSELTAG--STWHAAGLT-----TYFHP 101
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRG-FRVLVLEKRDRLGGnaYSYRVPGYVfdygaHIFHG 54
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 53-94 9.78e-03

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 39.05  E-value: 9.78e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 767935796  53 VIIGGGCVGVSLAYHLAKAGMKdVVLLEKSELTAGSTWHAAG 94
Cdd:COG1053    7 VVVGSGGAGLRAALEAAEAGLK-VLVLEKVPPRGGHTAAAQG 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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