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Conserved domains on  [gi|768015747|ref|XP_011526821|]
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centrosome-associated protein CEP250 isoform X10 [Homo sapiens]

Protein Classification

SMC_prok_B and PTZ00121 superfamily-containing protein( domain architecture ID 1033784)

protein containing superfamilies Smc, SMC_prok_B, and PTZ00121

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 588-1350 2.25e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 112.46  E-value: 2.25e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   588 LEVQIQTVTQAKEvIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLR-EKWEKERSw 666
Cdd:TIGR02168  205 LERQAEKAERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEE- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   667 hQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALcQMQLETEKERVSLLETLLQTQKELADASQQL 746
Cdd:TIGR02168  283 -IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE-SKLDELAEELAELEEKLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   747 ERLRQDMKVQKLKEQEttgilqtqLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ-- 824
Cdd:TIGR02168  361 EELEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLee 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   825 ---RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQM 901
Cdd:TIGR02168  433 aelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   902 E----------LLRQEVKEKEADFLAQEAQLLEELEA-----SHITEQQLRASLWAQEAKAAQLQLRLRS----TESQLE 962
Cdd:TIGR02168  513 KnqsglsgilgVLSELISVDEGYEAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKgteiQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   963 ALAAEQQPGNQAQAQAQLASLYS-ALQQALGSV-----CESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSA 1036
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRkALSYLLGGVlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1037 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1116
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1117 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVESE 1196
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1197 RERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQ 1276
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768015747  1277 IQELEKCRSVLEHLPMAVQEREQKLTVQREQIreLEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1350
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 227-850 1.35e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.35e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  227 EGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE 306
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  307 EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 386
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  387 TEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL 466
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  467 QKAEEAGAELQADLRDIQEEKEEIQKKLS-----ESRHQQEAATTQLEQLHQEAKRQEEVLA--RAVQEKEALVREKAAL 539
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLllleaEADYEGFLEGVKAALLLAGLRGLAGAVAvlIGVEAAYEAALEAALA 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  540 EVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEvtkgQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ 619
Cdd:COG1196   546 AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAAL----AAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  620 AEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 699
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  700 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELK 779
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE----LERELERLEREIE 777

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747  780 E------AArqhRDDLAALQEESSSLLQDKMDLQKQVEDLKsQLVAQddsqrlVEQEVQEKLRETqeYNRIQKELER 850
Cdd:COG1196   778 AlgpvnlLA---IEEYEELEERYDFLSEQREDLEEARETLE-EAIEE------IDRETRERFLET--FDAVNENFQE 842
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1057-1817 4.36e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 4.36e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1057 RDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1136
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1137 AQGERELLQAAKENLTAQVEHLQaavvearaqaSAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1216
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELE----------SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1217 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ--EQIQELEKCRSVLEHLPMAV 1294
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1295 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI 1374
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1375 KELEGQRETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1454
Cdd:TIGR02168  537 AAIEAALGGRLQAVVVENLNAAKKAIAFLKQN------ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1455 DQELMLqkeriqVLED--QRTRQTKILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIlRDK 1532
Cdd:TIGR02168  611 DPKLRK------ALSYllGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-EEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1533 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1612
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1613 R---DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGD 1689
Cdd:TIGR02168  763 IeelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1690 LRAESREQEKALLALQQQ---CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQE 1766
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  1767 ALGKAHAALQGKEQHLLEQAELSRSL--------EASTATLQASLDACQAHSRQLEEAL 1817
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKI 981
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1544-2111 7.36e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 7.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1544 HELQELKDQLEQQLQGLHRKVGETSL-LLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1622
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELeELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1623 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALL 1702
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1703 ALQQQCAEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1782
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1783 LEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKS 1862
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1863 LAQRVQENmiqEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSL 1942
Cdd:COG1196   535 AYEAALEA---ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1943 EPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEK 2022
Cdd:COG1196   612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 2023 ERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEpspdgMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVE 2102
Cdd:COG1196   692 ELELEEALLAEEEEERELAEAEEERLEEELEEE-----ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                  ....*....
gi 768015747 2103 RERRKLKRE 2111
Cdd:COG1196   767 RELERLERE 775
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 44-289 4.02e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 4.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   44 LLLLLAKTQELEKEAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELME 123
Cdd:COG4942     8 ALLLALAAAAQADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  124 HEASLSRNAQEEKLSLQQVIKDITQVMVEegdniAQGSGHENSLELdssIFSQFDYQDADKALTLVRSVLTRRRQAVQDL 203
Cdd:COG4942    84 ELAELEKEIAELRAELEAQKEELAELLRA-----LYRLGRQPPLAL---LLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  204 RQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQE 283
Cdd:COG4942   156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                  ....*.
gi 768015747  284 AWRLRR 289
Cdd:COG4942   236 AAAAAE 241
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 588-1350 2.25e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 112.46  E-value: 2.25e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   588 LEVQIQTVTQAKEvIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLR-EKWEKERSw 666
Cdd:TIGR02168  205 LERQAEKAERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEE- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   667 hQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALcQMQLETEKERVSLLETLLQTQKELADASQQL 746
Cdd:TIGR02168  283 -IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE-SKLDELAEELAELEEKLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   747 ERLRQDMKVQKLKEQEttgilqtqLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ-- 824
Cdd:TIGR02168  361 EELEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLee 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   825 ---RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQM 901
Cdd:TIGR02168  433 aelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   902 E----------LLRQEVKEKEADFLAQEAQLLEELEA-----SHITEQQLRASLWAQEAKAAQLQLRLRS----TESQLE 962
Cdd:TIGR02168  513 KnqsglsgilgVLSELISVDEGYEAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKgteiQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   963 ALAAEQQPGNQAQAQAQLASLYS-ALQQALGSV-----CESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSA 1036
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRkALSYLLGGVlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1037 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1116
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1117 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVESE 1196
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1197 RERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQ 1276
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768015747  1277 IQELEKCRSVLEHLPMAVQEREQKLTVQREQIreLEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1350
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 227-850 1.35e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.35e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  227 EGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE 306
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  307 EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 386
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  387 TEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL 466
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  467 QKAEEAGAELQADLRDIQEEKEEIQKKLS-----ESRHQQEAATTQLEQLHQEAKRQEEVLA--RAVQEKEALVREKAAL 539
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLllleaEADYEGFLEGVKAALLLAGLRGLAGAVAvlIGVEAAYEAALEAALA 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  540 EVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEvtkgQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ 619
Cdd:COG1196   546 AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAAL----AAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  620 AEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 699
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  700 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELK 779
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE----LERELERLEREIE 777

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747  780 E------AArqhRDDLAALQEESSSLLQDKMDLQKQVEDLKsQLVAQddsqrlVEQEVQEKLRETqeYNRIQKELER 850
Cdd:COG1196   778 AlgpvnlLA---IEEYEELEERYDFLSEQREDLEEARETLE-EAIEE------IDRETRERFLET--FDAVNENFQE 842
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 661-1247 6.87e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.78  E-value: 6.87e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  661 EKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmqlETEKERVSLLETLLQTQKELA 740
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE--------ELRLELEELELELEEAQAEEY 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  741 DASQQLERLRQDMKVQKLKEQettgilqtQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQ 820
Cdd:COG1196   292 ELLAELARLEQDIARLEERRR--------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  821 DDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 900
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  901 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQL 980
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  981 ASLysALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRgplltALSAEAVASALHKLHQDLWKTQQTRDVL 1060
Cdd:COG1196   524 GAV--AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKAGRATFLPLDKIRARAALAAALARGA 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1061 RDQVQKLEERLTDTEAEKSQVHtELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGE 1140
Cdd:COG1196   597 IGAAVDLVASDLREADARYYVL-GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1141 RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1220
Cdd:COG1196   676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                         570       580
                  ....*....|....*....|....*..
gi 768015747 1221 LALLtQTLAEREEEVETLRGQIQELEK 1247
Cdd:COG1196   756 LPEP-PDLEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1057-1817 4.36e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 4.36e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1057 RDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1136
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1137 AQGERELLQAAKENLTAQVEHLQaavvearaqaSAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1216
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELE----------SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1217 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ--EQIQELEKCRSVLEHLPMAV 1294
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1295 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI 1374
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1375 KELEGQRETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1454
Cdd:TIGR02168  537 AAIEAALGGRLQAVVVENLNAAKKAIAFLKQN------ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1455 DQELMLqkeriqVLED--QRTRQTKILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIlRDK 1532
Cdd:TIGR02168  611 DPKLRK------ALSYllGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-EEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1533 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1612
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1613 R---DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGD 1689
Cdd:TIGR02168  763 IeelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1690 LRAESREQEKALLALQQQ---CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQE 1766
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  1767 ALGKAHAALQGKEQHLLEQAELSRSL--------EASTATLQASLDACQAHSRQLEEAL 1817
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1387-1953 1.82e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1387 ALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQ 1466
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1467 VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHEL 1546
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1547 QELKdQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ 1626
Cdd:COG1196   393 RAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1627 AQGQEERVKEKADALQGALEQAHMTLKERhgELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQ 1706
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1707 QCAEQAQehevetralqdswlQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQA 1786
Cdd:COG1196   550 NIVVEDD--------------EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1787 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDV-QQLQQALAQRDEELRHQQEREQLLEKSLAQ 1865
Cdd:COG1196   616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEAEAELEELAERLAEEELEL 695

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1866 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDslepR 1945
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE----R 771


                  ....*...
gi 768015747 1946 LQRELERL 1953
Cdd:COG1196   772 LEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 254-912 2.56e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.90  E-value: 2.56e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  254 GEVDSLSKERELLQKArEELRQQLEVLEQEAWRlrrvnvelqlQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQ 333
Cdd:PTZ00121 1109 GKAEEARKAEEAKKKA-EDARKAEEARKAEDAR----------KAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKK 1177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  334 SESLSELITLREALESSHLEgELLRQEQtevtAALARAEQSIAELSSSENTLKTEvADLRAAAVKLSAlNEALALDKVGL 413
Cdd:PTZ00121 1178 AEAARKAEEVRKAEELRKAE-DARKAEA----ARKAEEERKAEEARKAEDAKKAE-AVKKAEEAKKDA-EEAKKAEEERN 1250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  414 NQQLLQLEEENQSVCSRMEA---AEQARNALQVDLAEAEKRREAL--WEKNTHLEAQLQKAEEA--GAELQADLRDIQEE 486
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAaikAEEARKADELKKAEEKKKADEAkkAEEKKKADEAKKKAEEAkkADEAKKKAEEAKKK 1330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  487 KEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV-----LARAVQEKEALVREKAALEVR----LQAVERDRQDLAEQL 557
Cdd:PTZ00121 1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKaeaaeKKKEEAKKKADAAKKKAEEKKkadeAKKKAEEDKKKADEL 1410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  558 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQI--QTVTQAKEVIQGEVRCLKLE----LDTERSQAEQERDA----- 626
Cdd:PTZ00121 1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKadEAKKKAEEAKKAEEAKKKAEeakkADEAKKKAEEAKKAdeakk 1490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  627 -------AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwhqQELAKALESLEREKMELEMRLKEQQTEMEAI 699
Cdd:PTZ00121 1491 kaeeakkKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA---DEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  700 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELaDASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELK 779
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM-KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK 1646

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  780 EAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLK----------SQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELE 849
Cdd:PTZ00121 1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkaeedekkaaEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE 1726

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768015747  850 REKASLTLSLMEKEQRLLVLQEAdSIRQQELSALRQDMQEAQGEQKELSAQME-LLRQEVKEKE 912
Cdd:PTZ00121 1727 ENKIKAEEAKKEAEEDKKKAEEA-KKDEEEKKKIAHLKKEEEKKAEEIRKEKEaVIEEELDEED 1789
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 39-749 2.35e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 2.35e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747    39 REPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH 118
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   119 TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFsqfdyQDADKALTLVRSVLTRRRQ 198
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-----EELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   199 AVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLtgERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLE 278
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   279 VLEQEAWRLRRVNVELQLQGDSaQGQKEEQQEELHLAVRERERLQEMLMGLEAkqseSLSELITLREALES--------- 349
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILG----VLSELISVDEGYEAaieaalggr 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   350 --------------------------------SHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAV 397
Cdd:TIGR02168  547 lqavvvenlnaakkaiaflkqnelgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   398 KLSALNEALALDK-VGLNQQLLQLEEENQSVCSRM----EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEA 472
Cdd:TIGR02168  627 VVDDLDNALELAKkLRPGYRIVTLDGDLVRPGGVItggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   473 GAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQD 552
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   553 LAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLA 632
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAE-------LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   633 QAE--QEGKTALEQQKAAHEKEVNQLREKWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 710
Cdd:TIGR02168  860 EIEelEELIEELESELEALLNERASLEEALALLRS-ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 768015747   711 E------SALCQMQLETEKERVSLLETLLQ-TQKELADASQQLERL 749
Cdd:TIGR02168  939 DnlqerlSEEYSLTLEEAEALENKIEDDEEeARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1544-2111 7.36e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 7.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1544 HELQELKDQLEQQLQGLHRKVGETSL-LLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1622
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELeELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1623 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALL 1702
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1703 ALQQQCAEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1782
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1783 LEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKS 1862
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1863 LAQRVQENmiqEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSL 1942
Cdd:COG1196   535 AYEAALEA---ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1943 EPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEK 2022
Cdd:COG1196   612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 2023 ERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEpspdgMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVE 2102
Cdd:COG1196   692 ELELEEALLAEEEEERELAEAEEERLEEELEEE-----ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                  ....*....
gi 768015747 2103 RERRKLKRE 2111
Cdd:COG1196   767 RELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 434-1288 2.22e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  434 AEQARNALQVDLAEAEKRREALweknthleaqlQKAEEAgaelqadlRDIQE-EKEEIQKKLSESRHQQEAATTQLEQLH 512
Cdd:PTZ00121 1100 AEEAKKTETGKAEEARKAEEAK-----------KKAEDA--------RKAEEaRKAEDARKAEEARKAEDAKRVEIARKA 1160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  513 QEAKRQEEvlARAVQEKEALVREKAALEVRlqaverdrqdLAEQLQGLSSAKELLESSLFEAQQQnsVIEVTKGQLEVQI 592
Cdd:PTZ00121 1161 EDARKAEE--ARKAEDAKKAEAARKAEEVR----------KAEELRKAEDARKAEAARKAEEERK--AEEARKAEDAKKA 1226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  593 QTVTQAKEVIQGEVRCLKLE---LDTERSQAEQERDA--AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwh 667
Cdd:PTZ00121 1227 EAVKKAEEAKKDAEEAKKAEeerNNEEIRKFEEARMAhfARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA-- 1304

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  668 qQELAKALESlEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSlletllQTQKELADASQQLE 747
Cdd:PTZ00121 1305 -DEAKKKAEE-AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA------EEKAEAAEKKKEEA 1376

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  748 RLRQDMKVQKLKEQETTGILQTQLQEAQREL-----KEAARQHRDDLAALQEE--SSSLLQDKMDLQKQVEDLKSQLvaq 820
Cdd:PTZ00121 1377 KKKADAAKKKAEEKKKADEAKKKAEEDKKKAdelkkAAAAKKKADEAKKKAEEkkKADEAKKKAEEAKKADEAKKKA--- 1453

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  821 ddSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRllvlQEADSIRQQELSALRQDmqeaQGEQKELSAQ 900
Cdd:PTZ00121 1454 --EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK----KKADEAKKAAEAKKKAD----EAKKAEEAKK 1523

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  901 MELLRQEVKEKEADFL--AQEAQLLEELEAShiteQQLRAslwAQEAKAAQlQLRLRSTESQLEALAAEQQPGNQAQAQA 978
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkAEEKKKADELKKA----EELKK---AEEKKKAE-EAKKAEEDKNMALRKAEEAKKAEEARIE 1595

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  979 QLASLYSALQQALGSVCESRPELSGGGDSAPSvwglepdqngARSLFKRGPLLTALSAEAVASAlhklhQDLWKTQQTRD 1058
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK----------AEEEKKKVEQLKKKEAEEKKKA-----EELKKAEEENK 1660

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1059 VLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQ 1138
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1139 GERellQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKAlQ 1218
Cdd:PTZ00121 1741 EDK---KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGK-E 1816

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1219 ENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLE 1288
Cdd:PTZ00121 1817 GNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEE 1886
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 607-1470 1.29e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 67.30  E-value: 1.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   607 RCLKLELDTERSQAEQERDAAaRQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELE 686
Cdd:pfam02463  190 IDLEELKLQELKLKEQAKKAL-EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   687 MRLKEQQTEMEAIQAQREEertqaesalcQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGI 766
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEE----------LKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   767 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQ-VEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQ 845
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeSERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   846 KELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQmELLRQEVKEKEADFLAQEAQLLEE 925
Cdd:pfam02463  419 DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL-LKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   926 LEAShitEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG 1005
Cdd:pfam02463  498 RSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1006 DSAPSVWGLEPDQNGARSLFKRGPLLTALSA----EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQV 1081
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLaqldKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1082 HTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAA 1161
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1162 VVEARAQASAAGILEEDLrTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1241
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEE-EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1242 IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKcrsvLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNV 1321
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE----ELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1322 LEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALEleenhHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQE 1401
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA-----EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  1402 LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLED 1470
Cdd:pfam02463  965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGW 1033
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1178-1697 1.15e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.91  E-value: 1.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1178 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALL-------TQTLAEREEEVETLRGQIQELEKQRE 1250
Cdd:PRK02224  210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLeaeiedlRETIAETEREREELAEEVRDLRERLE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1251 MQKAALELLSLDLKKRNQEVDLQQEQIQELEK----CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQL 1326
Cdd:PRK02224  290 ELEEERDDLLAEAGLDDADAEAVEARREELEDrdeeLRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1327 LELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE----LEGQRETQRVALTHLTLDLEERSQEL 1402
Cdd:PRK02224  370 SELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREerdeLREREAELEATLRTARERVEEAEALL 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1403 QAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ------ELMLQKERIQVLEDQRTRQT 1476
Cdd:PRK02224  450 EAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDlveaedRIERLEERREDLEELIAERR 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1477 KILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEcQQEHIHELQELKDQLEQQ 1556
Cdd:PRK02224  530 ETIEEKRERAE-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTLLAAIADAEDE 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1557 LQGLHRKVGETSLLLSQReqeivvlQQQLQEAREQ-GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVK 1635
Cdd:PRK02224  608 IERLREKREALAELNDER-------RERLAEKRERkRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQ 680

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768015747 1636 EKADALQGALEQAHmTLKERHGELQDHKEQARRLEEElavegrrVQALEEVLGDLRAESREQ 1697
Cdd:PRK02224  681 AEIGAVENELEELE-ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQR 734
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 44-289 4.02e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 4.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   44 LLLLLAKTQELEKEAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELME 123
Cdd:COG4942     8 ALLLALAAAAQADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  124 HEASLSRNAQEEKLSLQQVIKDITQVMVEegdniAQGSGHENSLELdssIFSQFDYQDADKALTLVRSVLTRRRQAVQDL 203
Cdd:COG4942    84 ELAELEKEIAELRAELEAQKEELAELLRA-----LYRLGRQPPLAL---LLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  204 RQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQE 283
Cdd:COG4942   156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                  ....*.
gi 768015747  284 AWRLRR 289
Cdd:COG4942   236 AAAAAE 241
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1288-1914 8.39e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 8.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1288 EHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENH-HK 1366
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTvHE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1367 MECQQKLIKELEGQRETQRVALTHLTLDLEERSQEL--------QAQSSQIHDLESHSTV--------LARELQERDQEV 1430
Cdd:pfam15921  154 LEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeEASGKKIYEHDSMSTMhfrslgsaISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1431 KSQREQIEELQRQKEHLTQDLERRdQELMLQKERIQVleDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEE 1510
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNK-IELLLQQHQDRI--EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1511 GKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHElqelkdQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEARE 1590
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIE------ELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLA 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1591 QGELKEQSLQSQLDEAQRaLAQRDQELEALQQEQQQAQGQEERVKEKADAL--------QGALEQAHMTLKERH------ 1656
Cdd:pfam15921  385 DLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALlkamksecQGQMERQMAAIQGKNeslekv 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1657 ----GELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCaeqaqeheVETRALQDSWLQAQAV 1732
Cdd:pfam15921  464 ssltAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEI--------TKLRSRVDLKLQELQH 535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1733 LKERDQELEALRAESQSSRHQEEAARARAEALQEalgkahaALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQ 1812
Cdd:pfam15921  536 LKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ-------QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQE 608

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1813 LEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRH----QQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIR 1888
Cdd:pfam15921  609 FKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSE 688

                          650       660
                   ....*....|....*....|....*.
gi 768015747  1889 GLHQSVRELQLTLAQKEQEILELRET 1914
Cdd:pfam15921  689 EMETTTNKLKMQLKSAQSELEQTRNT 714
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 49-399 2.30e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 2.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747    49 AKTQELEKEAHERSQELIQLKSQGDL---EKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHE 125
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEEleeELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   126 ASLSRNAQEEKLSLQQVIKDITQVMveegdniAQGSGHENSLELDSSIFSqfdyqDADKALTLVRSVLTRRRQAVQDLRQ 205
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELE-------AQIEQLKEELKALREALD-----ELRAELTLLNEEAANLRERLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   206 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAW 285
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   286 RLRRVNVELQLQ-GDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESshlegelLRQEQTEV 364
Cdd:TIGR02168  912 ELRRELEELREKlAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-------LENKIKEL 984

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 768015747   365 TAALARAEQSIAELSSSENTLKTEVADLRAAAVKL 399
Cdd:TIGR02168  985 GPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETL 1019
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 216-918 1.34e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.74  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   216 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQ 295
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   296 LQGDSAQGQKEEQQEELHLAVRE-------RERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAAL 368
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEaqlllelARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   369 ARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEA 448
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   449 EKRRE--ALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAV 526
Cdd:pfam02463  544 AISTAviVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   527 QEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEV 606
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   607 RCLKLELDTERSQAEQERDAAARQ---LAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKM 683
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVqeaQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKT 783

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   684 ELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQET 763
Cdd:pfam02463  784 EKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   764 TGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEvQEKLRETQEYNR 843
Cdd:pfam02463  864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL-LKYEEEPEELLL 942

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747   844 IQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQ 918
Cdd:pfam02463  943 EEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PTZ00121 PTZ00121
MAEBL; Provisional
 1784-2214 1.37e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1784 EQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALaqRDEELRHQQEREQLlekSL 1863
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR--KAEEARKAEDAKRV---EI 1156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1864 AQRVQE-NMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEE----QSLK 1938
Cdd:PTZ00121 1157 ARKAEDaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAvkkaEEAK 1236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1939 LDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRR 2018
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKK 1316

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 2019 ALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTL 2098
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 2099 EQVERERRKLKREAMRAAQA-GSLEISKATASSPTQQDGRGQKNSDAKCVAELQKEV----VLLQAQLTLERKQKQDYIT 2173
Cdd:PTZ00121 1397 KKKAEEDKKKADELKKAAAAkKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAeeakKAEEAKKKAEEAKKADEAK 1476

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 768015747 2174 RSAQTSRElagLHHSLSHSLLAVAQAPEATVLEAETRRLDE 2214
Cdd:PTZ00121 1477 KKAEEAKK---ADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 446-822 1.90e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 46.54  E-value: 1.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  446 AEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLrdiqeekEEIQKKLSESRHQQEAA-TTQLEQLHQEAKRQEEVLaR 524
Cdd:NF033838   37 AEEVRGGNNPTVTSSGNESQKEHAKEVESHLEKIL-------SEIQKSLDKRKHTQNVAlNKKLSDIKTEYLYELNVL-K 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  525 AVQEKEALVREKAALEVrlqAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAK---EV 601
Cdd:NF033838  109 EKSEAELTSKTKKELDA---AFEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQ-------KEEDRRNYPTNTYKTlelEI 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  602 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTAleqqKAAHEKEVNQLREKWEKE-RSWHQQELAKALESL-- 678
Cdd:NF033838  179 AESDVEVKKAELELVKEEAKEPRDEEKIKQAKAKVESKKA----EATRLEKIKTDREKAEEEaKRRADAKLKEAVEKNva 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  679 EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQmqlETekervsLLETLLQTQKELADASQQLERLRQDMKVQKL 758
Cdd:NF033838  255 TSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDSSVGE---ET------LPSPSLKPEKKVAEAEKKVEEAKKKAKDQKE 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  759 KEQE-----TTGILQTQLQEAQRELKEA-----------------ARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQ 816
Cdd:NF033838  326 EDRRnyptnTYKTLELEIAESDVKVKEAelelvkeeakeprneekIKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRK 405


                  ....*.
gi 768015747  817 LVAQDD 822
Cdd:NF033838  406 AAEEDK 411
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1845-2122 3.10e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.75  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1845 RDEELRHQQEREQLLE---KSLAQRVQENMIQEKQNLGQ-EREEEEIRGLHQSVRELQLTLAQKEQEILEL-RETQQRNN 1919
Cdd:TIGR02169  207 REKAERYQALLKEKREyegYELLKEKEALERQKEAIERQlASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1920 LEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAR------EIE-WREKAQDLALSLAQTKASVSSLQEVA 1992
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEidkllaEIEeLEREIEEERKRRDKLTEEYAELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1993 MFLQASVLERDSEQQRLQDELELTRRALEK-ERLHSPGATSTAELGSRGEQGVQLG-----EVSGVEAEPSPDGMEKQSW 2066
Cdd:TIGR02169  367 EDLRAELEEVDKEFAETRDELKDYREKLEKlKREINELKRELDRLQEELQRLSEELadlnaAIAGIEAKINELEEEKEDK 446

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747  2067 RQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRA-AQAGSLE 2122
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeAQARASE 503
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 588-1350 2.25e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 112.46  E-value: 2.25e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   588 LEVQIQTVTQAKEvIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLR-EKWEKERSw 666
Cdd:TIGR02168  205 LERQAEKAERYKE-LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlEVSELEEE- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   667 hQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALcQMQLETEKERVSLLETLLQTQKELADASQQL 746
Cdd:TIGR02168  283 -IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE-SKLDELAEELAELEEKLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   747 ERLRQDMKVQKLKEQEttgilqtqLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ-- 824
Cdd:TIGR02168  361 EELEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLee 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   825 ---RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQM 901
Cdd:TIGR02168  433 aelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   902 E----------LLRQEVKEKEADFLAQEAQLLEELEA-----SHITEQQLRASLWAQEAKAAQLQLRLRS----TESQLE 962
Cdd:TIGR02168  513 KnqsglsgilgVLSELISVDEGYEAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVTFLPLDSIKgteiQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   963 ALAAEQQPGNQAQAQAQLASLYS-ALQQALGSV-----CESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSA 1036
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRkALSYLLGGVlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1037 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1116
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1117 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVESE 1196
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE---LRAELTLLNEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1197 RERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQ 1276
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768015747  1277 IQELEKCRSVLEHLPMAVQEREQKLTVQREQIreLEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1350
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 227-850 1.35e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.09  E-value: 1.35e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  227 EGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE 306
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  307 EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLK 386
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  387 TEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL 466
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  467 QKAEEAGAELQADLRDIQEEKEEIQKKLS-----ESRHQQEAATTQLEQLHQEAKRQEEVLA--RAVQEKEALVREKAAL 539
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLllleaEADYEGFLEGVKAALLLAGLRGLAGAVAvlIGVEAAYEAALEAALA 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  540 EVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEvtkgQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ 619
Cdd:COG1196   546 AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAAL----AAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  620 AEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 699
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  700 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELK 779
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE----LERELERLEREIE 777

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747  780 E------AArqhRDDLAALQEESSSLLQDKMDLQKQVEDLKsQLVAQddsqrlVEQEVQEKLRETqeYNRIQKELER 850
Cdd:COG1196   778 AlgpvnlLA---IEEYEELEERYDFLSEQREDLEEARETLE-EAIEE------IDRETRERFLET--FDAVNENFQE 842
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 661-1247 6.87e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.78  E-value: 6.87e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  661 EKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmqlETEKERVSLLETLLQTQKELA 740
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE--------ELRLELEELELELEEAQAEEY 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  741 DASQQLERLRQDMKVQKLKEQettgilqtQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQ 820
Cdd:COG1196   292 ELLAELARLEQDIARLEERRR--------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  821 DDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 900
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  901 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQL 980
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  981 ASLysALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRgplltALSAEAVASALHKLHQDLWKTQQTRDVL 1060
Cdd:COG1196   524 GAV--AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-----AKAGRATFLPLDKIRARAALAAALARGA 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1061 RDQVQKLEERLTDTEAEKSQVHtELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGE 1140
Cdd:COG1196   597 IGAAVDLVASDLREADARYYVL-GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1141 RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1220
Cdd:COG1196   676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                         570       580
                  ....*....|....*....|....*..
gi 768015747 1221 LALLtQTLAEREEEVETLRGQIQELEK 1247
Cdd:COG1196   756 LPEP-PDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 180-705 1.38e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 99.63  E-value: 1.38e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  180 QDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSL 259
Cdd:COG1196   263 AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  260 SKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE 339
Cdd:COG1196   343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  340 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQ 419
Cdd:COG1196   423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  420 LEEENQSVCSRMEAAEQARNALQVDlaeaekrrEALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 499
Cdd:COG1196   503 YEGFLEGVKAALLLAGLRGLAGAVA--------VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA 574

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  500 QQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 579
Cdd:COG1196   575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  580 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 659
Cdd:COG1196   655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 768015747  660 WEKERswHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREE 705
Cdd:COG1196   735 EELLE--ELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1057-1817 4.36e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 4.36e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1057 RDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1136
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1137 AQGERELLQAAKENLTAQVEHLQaavvearaqaSAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1216
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELE----------SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1217 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ--EQIQELEKCRSVLEHLPMAV 1294
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1295 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI 1374
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1375 KELEGQRETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1454
Cdd:TIGR02168  537 AAIEAALGGRLQAVVVENLNAAKKAIAFLKQN------ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1455 DQELMLqkeriqVLED--QRTRQTKILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIlRDK 1532
Cdd:TIGR02168  611 DPKLRK------ALSYllGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-EEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1533 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1612
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1613 R---DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGD 1689
Cdd:TIGR02168  763 IeelEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1690 LRAESREQEKALLALQQQ---CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQE 1766
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEieeLEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  1767 ALGKAHAALQGKEQHLLEQAELSRSL--------EASTATLQASLDACQAHSRQLEEAL 1817
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1387-1953 1.82e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 96.16  E-value: 1.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1387 ALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQ 1466
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1467 VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHEL 1546
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1547 QELKdQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ 1626
Cdd:COG1196   393 RAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1627 AQGQEERVKEKADALQGALEQAHMTLKERhgELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQ 1706
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1707 QCAEQAQehevetralqdswlQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQA 1786
Cdd:COG1196   550 NIVVEDD--------------EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARY 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1787 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDV-QQLQQALAQRDEELRHQQEREQLLEKSLAQ 1865
Cdd:COG1196   616 YVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEAEAELEELAERLAEEELEL 695

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1866 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDslepR 1945
Cdd:COG1196   696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE----R 771


                  ....*...
gi 768015747 1946 LQRELERL 1953
Cdd:COG1196   772 LEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 179-749 1.44e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.08  E-value: 1.44e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  179 YQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLagqtvdlQGEVDS 258
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL-------EQDIAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  259 LSKERELLQKAREELRQQLEVLEQEAwrlrrvnVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLS 338
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEEL-------EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  339 ELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLL 418
Cdd:COG1196   380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  419 QLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALweknthLEAQLQKAEEAGAELQADLRDIQeekEEIQKKLSESR 498
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLL------LEAEADYEGFLEGVKAALLLAGL---RGLAGAVAVLI 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  499 HQQEAATTQLEQLHQEAkRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQN 578
Cdd:COG1196   531 GVEAAYEAALEAALAAA-LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  579 SVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE 658
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  659 KWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKE 738
Cdd:COG1196   690 EEELELE-EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                         570
                  ....*....|.
gi 768015747  739 LADASQQLERL 749
Cdd:COG1196   769 LERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 254-912 2.56e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.90  E-value: 2.56e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  254 GEVDSLSKERELLQKArEELRQQLEVLEQEAWRlrrvnvelqlQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQ 333
Cdd:PTZ00121 1109 GKAEEARKAEEAKKKA-EDARKAEEARKAEDAR----------KAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKK 1177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  334 SESLSELITLREALESSHLEgELLRQEQtevtAALARAEQSIAELSSSENTLKTEvADLRAAAVKLSAlNEALALDKVGL 413
Cdd:PTZ00121 1178 AEAARKAEEVRKAEELRKAE-DARKAEA----ARKAEEERKAEEARKAEDAKKAE-AVKKAEEAKKDA-EEAKKAEEERN 1250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  414 NQQLLQLEEENQSVCSRMEA---AEQARNALQVDLAEAEKRREAL--WEKNTHLEAQLQKAEEA--GAELQADLRDIQEE 486
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAaikAEEARKADELKKAEEKKKADEAkkAEEKKKADEAKKKAEEAkkADEAKKKAEEAKKK 1330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  487 KEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV-----LARAVQEKEALVREKAALEVR----LQAVERDRQDLAEQL 557
Cdd:PTZ00121 1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKaeaaeKKKEEAKKKADAAKKKAEEKKkadeAKKKAEEDKKKADEL 1410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  558 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQI--QTVTQAKEVIQGEVRCLKLE----LDTERSQAEQERDA----- 626
Cdd:PTZ00121 1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKadEAKKKAEEAKKAEEAKKKAEeakkADEAKKKAEEAKKAdeakk 1490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  627 -------AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwhqQELAKALESLEREKMELEMRLKEQQTEMEAI 699
Cdd:PTZ00121 1491 kaeeakkKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA---DEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  700 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELaDASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELK 779
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM-KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK 1646

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  780 EAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLK----------SQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELE 849
Cdd:PTZ00121 1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkaeedekkaaEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEE 1726

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768015747  850 REKASLTLSLMEKEQRLLVLQEAdSIRQQELSALRQDMQEAQGEQKELSAQME-LLRQEVKEKE 912
Cdd:PTZ00121 1727 ENKIKAEEAKKEAEEDKKKAEEA-KKDEEEKKKIAHLKKEEEKKAEEIRKEKEaVIEEELDEED 1789
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 39-749 2.35e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 2.35e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747    39 REPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH 118
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   119 TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFsqfdyQDADKALTLVRSVLTRRRQ 198
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-----EELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   199 AVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLtgERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLE 278
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   279 VLEQEAWRLRRVNVELQLQGDSaQGQKEEQQEELHLAVRERERLQEMLMGLEAkqseSLSELITLREALES--------- 349
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILG----VLSELISVDEGYEAaieaalggr 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   350 --------------------------------SHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAV 397
Cdd:TIGR02168  547 lqavvvenlnaakkaiaflkqnelgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   398 KLSALNEALALDK-VGLNQQLLQLEEENQSVCSRM----EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEA 472
Cdd:TIGR02168  627 VVDDLDNALELAKkLRPGYRIVTLDGDLVRPGGVItggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   473 GAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQD 552
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   553 LAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLA 632
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAE-------LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   633 QAE--QEGKTALEQQKAAHEKEVNQLREKWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 710
Cdd:TIGR02168  860 EIEelEELIEELESELEALLNERASLEEALALLRS-ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*.
gi 768015747   711 E------SALCQMQLETEKERVSLLETLLQ-TQKELADASQQLERL 749
Cdd:TIGR02168  939 DnlqerlSEEYSLTLEEAEALENKIEDDEEeARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 234-927 2.69e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.69e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   234 RLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELH 313
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   314 LAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLR 393
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   394 AAAVKLSALNEALALDKVGLNQQLLQLEEENQSVcsRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAG 473
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   474 AELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL-VREK------AALEVRLQAV 546
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIsVDEGyeaaieAALGGRLQAV 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   547 ERDRQDLAEQLQG----------------LSSAKELLESSLFEAQQQNSVIEVTK------------------------- 585
Cdd:TIGR02168  551 VVENLNAAKKAIAflkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllggvlvvdd 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   586 --------GQLEVQIQTVTQAKEVIQG---------EVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAA 648
Cdd:TIGR02168  631 ldnalelaKKLRPGYRIVTLDGDLVRPggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   649 HEKEVNQLREKWEKERSWHQQElaKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQlETEKERVSL 728
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALR--KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA-EAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   729 LETLLQTQKELADASQQLERLRQDMkvqklkeqettgilqTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQK 808
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAEL---------------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   809 QVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQ 888
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 768015747   889 EAQGE----QKELSAQMELLRQEVKEKEADFLAQEAQLLEELE 927
Cdd:TIGR02168  933 GLEVRidnlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 651-1498 2.76e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.76e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   651 KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmqlETEKERVSLLE 730
Cdd:TIGR02168  210 EKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE--------ELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   731 TLLQTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELKEAARQH---RDDLAALQEESSSLLQDKMDLQ 807
Cdd:TIGR02168  282 EIEELQKELYALANEISRLEQQKQILRERLAN----LERQLEELEAQLEELESKLdelAEELAELEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   808 KQVEDLKSQLVAQDDSQRLVEQEVQEklretqeYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDM 887
Cdd:TIGR02168  358 AELEELEAELEELESRLEELEEQLET-------LRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   888 QEAqgEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASlwaqEAKAAQLQLRLRSTESQLEALaae 967
Cdd:TIGR02168  431 EEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA----ERELAQLQARLDSLERLQENL--- 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   968 QQPGNQAQAQAQLASLYSALQQALGSVCESRPELSgggdsapsvwglepdqngarslfkrgpllTALSAEAVASALHKLH 1047
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE-----------------------------AAIEAALGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1048 QDLwktQQTRDVLRDQVQKLEERLTDTEAeKSQVHTELQDLQRQLSQNQEEkskWEGKQNSLESELMELHETMASLQSRL 1127
Cdd:TIGR02168  553 ENL---NAAKKAIAFLKQNELGRVTFLPL-DSIKGTEIQGNDREILKNIEG---FLGVAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1128 RRAELQRmEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAG----------ILEEDLRTARSALKLKNEEVESER 1197
Cdd:TIGR02168  626 LVVDDLD-NALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreieELEEKIEELEEKIAELEKALAELR 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1198 ERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1277
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1278 QELEKcrsvlehlpmAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLvtlecla 1357
Cdd:TIGR02168  785 EELEA----------QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI------- 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1358 leleenhhkmECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1437
Cdd:TIGR02168  848 ----------EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  1438 EELQRQKEHLTQDLERRDQELMLQKERI----QVLEDQRTRQTKILEEDLEQIKLSLRERGRELT 1498
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDNLQERLseeySLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1198-1770 7.04e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 87.68  E-value: 7.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1198 ERAQALQE-----QGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDL 1272
Cdd:COG1196   213 ERYRELKEelkelEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1273 QQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVT 1352
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1353 LECLALELEENhhkmecQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKS 1432
Cdd:COG1196   373 ELAEAEEELEE------LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1433 QREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKlslrERGRELTTQRQLMQERAEEGK 1512
Cdd:COG1196   447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA----DYEGFLEGVKAALLLAGLRGL 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1513 GPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ--EIVVLQQQLQEARE 1590
Cdd:COG1196   523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAalAAALARGAIGAAVD 602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1591 QGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERhGELQDHKEQARRLE 1670
Cdd:COG1196   603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR-RELLAALLEAEAEL 681

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1671 EELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSS 1750
Cdd:COG1196   682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                         570       580
                  ....*....|....*....|
gi 768015747 1751 RHQEEAARARAEALQEALGK 1770
Cdd:COG1196   762 LEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 363-1247 7.28e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.80  E-value: 7.28e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   363 EVTAALARAEQSIAELSSSENTLKTEVAdlraAAVKLSALNEAL-ALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNAL 441
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAE----KAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   442 QVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV 521
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   522 LARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEv 601
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE- 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   602 iqgevrclklELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLERE 681
Cdd:TIGR02168  418 ----------RLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   682 KMELEMRLKEQQTEMEAIQAQREEERTQAESA----LCQMQLETEKERVSLLETLLQ------TQKELADASQQLERLRQ 751
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgVLSELISVDEGYEAAIEAALGgrlqavVVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   752 DmKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSsllqdkmDLQKQVEDLKSQLVAQDDSqrlveQEV 831
Cdd:TIGR02168  568 N-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDP-------KLRKALSYLLGGVLVVDDL-----DNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   832 QEKLRETQEYNRI---QKELEREKASLT-------LSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQM 901
Cdd:TIGR02168  635 LELAKKLRPGYRIvtlDGDLVRPGGVITggsaktnSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   902 ELLRQEVKEKEADFLAQEAQLL-EELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQL 980
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLArLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   981 ASLYSALQQALGSVcesRPELSgggdsapsvwglepdqngarslfkrgplLTALSAEAVASALHKLHQDLWKTQQTRDVL 1060
Cdd:TIGR02168  795 KEELKALREALDEL---RAELT----------------------------LLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1061 RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGE 1140
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1141 RELLQAAKENLTAQVEHLQAAVVEaRAQASAAGILEEDLRTARSALKLKnEEVESERERAQALQEQGELKVAQGKALQEN 1220
Cdd:TIGR02168  924 LAQLELRLEGLEVRIDNLQERLSE-EYSLTLEEAEALENKIEDDEEEAR-RRLKRLENKIKELGPVNLAAIEEYEELKER 1001

                          890       900
                   ....*....|....*....|....*..
gi 768015747  1221 LALLTQTLAEREEEVETLRGQIQELEK 1247
Cdd:TIGR02168 1002 YDFLTAQKEDLTEAKETLEEAIEEIDR 1028
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 266-964 1.05e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.03  E-value: 1.05e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   266 LQKAREELRQQLEVLEQE---AWRLRRVNVEL-QLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELI 341
Cdd:TIGR02168  191 LEDILNELERQLKSLERQaekAERYKELKAELrELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   342 TLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLE 421
Cdd:TIGR02168  271 ELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   422 EENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsrHQQ 501
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE--LLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   502 EAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQ-QNSV 580
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   581 IEVTKGQLE--------------------------------VQIQTVTQAKEVIQ-----GEVRCLKLELDTERSQAEQE 623
Cdd:TIGR02168  509 KALLKNQSGlsgilgvlselisvdegyeaaieaalggrlqaVVVENLNAAKKAIAflkqnELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   624 RDAAARQLAQAEQ----------------------------EGKTALEQQKAAHEK----------------------EV 653
Cdd:TIGR02168  589 NDREILKNIEGFLgvakdlvkfdpklrkalsyllggvlvvdDLDNALELAKKLRPGyrivtldgdlvrpggvitggsaKT 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   654 NQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQT-EMEAIQAQREEERTQAESALCQMQLETEKERV-SLLET 731
Cdd:TIGR02168  669 NSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEElEEELEQLRKELEELSRQISALRKDLARLEAEVeQLEER 748

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   732 LLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQtQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 811
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE-ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   812 DLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQ 891
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747   892 GEQKELSAQMELLRQ---EVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQ-EAKAAQLQLRLRSTESQLEAL 964
Cdd:TIGR02168  908 SKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1434-2022 1.33e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.53  E-value: 1.33e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1434 REQIEELQRQKEH------LTQDLERRDQELMLQK-ERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQE 1506
Cdd:COG1196   199 ERQLEPLERQAEKaeryreLKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1507 RAEEgkgpSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQ 1586
Cdd:COG1196   279 LELE----LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1587 EAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQA 1666
Cdd:COG1196   355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1667 RRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAvlkerdQELEALRAE 1746
Cdd:COG1196   435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA------EADYEGFLE 508

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1747 SQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGE--I 1824
Cdd:COG1196   509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARaaL 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1825 QDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQK 1904
Cdd:COG1196   589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1905 EQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKAS 1984
Cdd:COG1196   669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 768015747 1985 VSSLQEvamflQASVLERDSEQQRLQDELELTRRALEK 2022
Cdd:COG1196   749 EEEALE-----ELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1070-1612 6.53e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.22  E-value: 6.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1070 RLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG----ERELLQ 1145
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1146 AAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLT 1225
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1226 QTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQR 1305
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1306 EQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQR 1385
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1386 VALTHLTLDLEERSQELQA------QSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELM 1459
Cdd:COG1196   553 VEDDEVAAAAIEYLKAAKAgratflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1460 LQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEgkgpskaQRGSLEHMKLILRDKEKEVECQ 1539
Cdd:COG1196   633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE-------LAERLAEEELELEEALLAEEEE 705

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747 1540 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1612
Cdd:COG1196   706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 43-568 7.94e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.22  E-value: 7.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   43 QLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELm 122
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI- 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  123 EHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQD 202
Cdd:COG1196   305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  203 LRQQLAGCQEAVNLLQQQHDQwEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQ 282
Cdd:COG1196   385 AEELLEALRAAAELAAQLEEL-EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  283 EAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLR-------EALESSHLEGE 355
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligvEAAYEAALEAA 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  356 LLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENqSVCSRMEAAE 435
Cdd:COG1196   544 LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD-ARYYVLGDTL 622

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  436 QARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEA 515
Cdd:COG1196   623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 768015747  516 KRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLE 568
Cdd:COG1196   703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1218-1990 8.37e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.34  E-value: 8.37e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1218 QENLALLTQTLAEREEEVETLRGQ----IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEkcrSVLEHLPMA 1293
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERQaekaERYKELKAELRELELALLVLRLEELREELEELQEELKEAE---EELEELTAE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1294 VQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEEnhhKMECQQKL 1373
Cdd:TIGR02168  262 LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES---KLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1374 IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLER 1453
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1454 RDQELMLQKERIQVLEDQRTR----QTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLIL 1529
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQaeleELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1530 RDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVG---ETSLLLSQREQEIVV----LQQQLQEAREQGELKEQSLQSQ 1602
Cdd:TIGR02168  499 ENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyeaAIEAALGGRLQAVVVenlnAAKKAIAFLKQNELGRVTFLPL 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1603 LDEAQRALAQRDQELEALQQEQQQAQGQEERVKEK--------------ADALQGALEQAH-MTLKERHGELQDHKEQAR 1667
Cdd:TIGR02168  579 DSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvVDDLDNALELAKkLRPGYRIVTLDGDLVRPG 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1668 ------RLEEELAVEGRRVQ--ALEEVLGDLRAESREQEKALLALQQQCAEQaqehEVETRALQDSWLQAQAVLKERDQE 1739
Cdd:TIGR02168  659 gvitggSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEEL----EEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1740 LEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDacqahsrQLEEALRI 1819
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK-------ALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1820 QEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQL 1899
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1900 TLAQKEQEILELRETQQRNNLEALP----HSHKTSPMEEQSLKLDSLEPRLQRELERLqAALRQTEAREIEwrEKAQDLA 1975
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSElrreLEELREKLAQLELRLEGLEVRIDNLQERL-SEEYSLTLEEAE--ALENKIE 964

                          810
                   ....*....|....*
gi 768015747  1976 LSLAQTKASVSSLQE 1990
Cdd:TIGR02168  965 DDEEEARRRLKRLEN 979
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 612-1456 2.26e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 82.81  E-value: 2.26e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   612 ELDTERSQAEQERDAAARQLAQAE---QEGKTALEQQKAAHEK--EVNQLREKWEKERSWhqqELAKALESLEREKMELE 686
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDliiDEKRQQLERLRREREKaeRYQALLKEKREYEGY---ELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   687 MRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQEttgi 766
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELED---- 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   767 LQTQLQEAQRELKEAARQHRDDLAALQEEsssllqdkmdlQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK 846
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEE-----------RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   847 ELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEadflaqeaQLLEEL 926
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE--------WKLEQL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   927 EASHITEQQlraSLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLAS--LYSALQQALGSVCE-------- 996
Cdd:TIGR02169  461 AADLSKYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEevLKASIQGVHGTVAQlgsvgery 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   997 -SRPELSGGG----------DSAPSVWGLEPDQNGARSLF--------KRGPLLTALSAEAVASALHKLHQDLWKTQQTR 1057
Cdd:TIGR02169  538 aTAIEVAAGNrlnnvvveddAVAKEAIELLKRRKAGRATFlplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1058 DVLRDQ--VQKLEE-RLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQR 1134
Cdd:TIGR02169  618 YVFGDTlvVEDIEAaRRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1135 MEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQg 1214
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK- 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1215 kaLQENLALLTQTLAerEEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAV 1294
Cdd:TIGR02169  777 --LEEALNDLEARLS--HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1295 QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL-VTLECLALELEENHHKMECQQKL 1373
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELeAQIEKKRKRLSELKAKLEALEEE 932

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1374 IKELEgQRETQRVALTHLTLDLEERSQELQAQSSQIHDLEShstVLARELQERDQEVKSQREQIEELQRQKEHLTQDLER 1453
Cdd:TIGR02169  933 LSEIE-DPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEP---VNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILER 1008


                   ...
gi 768015747  1454 RDQ 1456
Cdd:TIGR02169 1009 IEE 1011
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 343-1151 3.23e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.23e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   343 LREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEE 422
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   423 ENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQE 502
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   503 AATTQLEQLHQEAKRQEEVLARAVQEKEALvrEKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIE 582
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   583 VTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAAR-----QLAQAEQEGKTALEqqkAAHEKEVNQLR 657
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlsELISVDEGYEAAIE---AALGGRLQAVV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   658 EKwekerswHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAL--CQMQLETEKERVSLLETLLQT 735
Cdd:TIGR02168  552 VE-------NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLgvAKDLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   736 ---QKELADASQQLERLRQDMKVQKLK-EQETTGILQTQlqeaQRELKEAARQHRddlaalQEESSSLLQDKMDLQKQVE 811
Cdd:TIGR02168  625 vlvVDDLDNALELAKKLRPGYRIVTLDgDLVRPGGVITG----GSAKTNSSILER------RREIEELEEKIEELEEKIA 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   812 DLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQ 891
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   892 GEQKELSAQMELLRQEVKEKEADFLAQEAQlLEELEASHiteQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPG 971
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKALREA-LDELRAEL---TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   972 NQAQaqaqlaslySALQQALGSVCESRPELSgggdsapsvwglepdqngarslfkrgplltalsaeavaSALHKLHQDLW 1051
Cdd:TIGR02168  851 SEDI---------ESLAAEIEELEELIEELE--------------------------------------SELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1052 KTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRL-RRA 1130
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALeNKI 963

                          810       820
                   ....*....|....*....|.
gi 768015747  1131 ELQRMEAQGERELLQAAKENL 1151
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 507-1161 1.54e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.98  E-value: 1.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  507 QLEQLHQEAKRQEEvlARAVQEKEALVREKAALevrlqaveRDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKG 586
Cdd:COG1196   201 QLEPLERQAEKAER--YRELKEELKELEAELLL--------LKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  587 QLEVQIQTVTQAKEVIQGEVRclklELDTERSQAEQERDAAARQLAQAEQEgktaleqqkaahEKEVNQLREKWEKERSW 666
Cdd:COG1196   271 ELRLELEELELELEEAQAEEY----ELLAELARLEQDIARLEERRRELEER------------LEELEEELAELEEELEE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  667 HQQELAKALESLEREKMELEMRLKEQQtemEAIQAQREEERTQAEsalcqmQLETEKERVSLLETLLQTQKELADASQQL 746
Cdd:COG1196   335 LEEELEELEEELEEAEEELEEAEAELA---EAEEALLEAEAELAE------AEEELEELAEELLEALRAAAELAAQLEEL 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  747 ERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL 826
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  827 VEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQEL--SALRQDMQEAQGEQKELSAQMELL 904
Cdd:COG1196   486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAleAALAAALQNIVVEDDEVAAAAIEY 565

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  905 RQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLY 984
Cdd:COG1196   566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  985 SALQQALGSVCESRPELSGGGdsapsvwglepdQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQV 1064
Cdd:COG1196   646 LREVTLEGEGGSAGGSLTGGS------------RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1065 QKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEkskwegkQNSLESELMELHETMASLQSRLRRAELQR-------MEA 1137
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEEL-------LEEEALEELPEPPDLEELERELERLEREIealgpvnLLA 786

                         650       660
                  ....*....|....*....|....
gi 768015747 1138 QGERELLQAAKENLTAQVEHLQAA 1161
Cdd:COG1196   787 IEEYEELEERYDFLSEQREDLEEA 810
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1522-2081 1.90e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1522 LEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQS 1601
Cdd:COG1196   227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1602 QLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1681
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1682 ALEEVLGDlRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARA 1761
Cdd:COG1196   387 ELLEALRA-AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1762 EALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQA 1841
Cdd:COG1196   466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1842 LAQRD---EELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRN 1918
Cdd:COG1196   546 AALQNivvEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1919 NLEALphshktsPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQAS 1998
Cdd:COG1196   626 TLVAA-------RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1999 VLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRgEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVA 2078
Cdd:COG1196   699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE-ELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777


                  ...
gi 768015747 2079 RLE 2081
Cdd:COG1196   778 ALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1544-2111 7.36e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 7.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1544 HELQELKDQLEQQLQGLHRKVGETSL-LLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ 1622
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELeELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1623 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALL 1702
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1703 ALQQQCAEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1782
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1783 LEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKS 1862
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1863 LAQRVQENmiqEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSL 1942
Cdd:COG1196   535 AYEAALEA---ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1943 EPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEK 2022
Cdd:COG1196   612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 2023 ERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEpspdgMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVE 2102
Cdd:COG1196   692 ELELEEALLAEEEEERELAEAEEERLEEELEEE-----ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766


                  ....*....
gi 768015747 2103 RERRKLKRE 2111
Cdd:COG1196   767 RELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 255-851 3.29e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.95  E-value: 3.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  255 EVDSLSKERELLQKArEELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHlAVRERERLQEMLMGLEAKQS 334
Cdd:PTZ00121 1303 KADEAKKKAEEAKKA-DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEEKAEAAEKKKEEAKKKA 1380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  335 ESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSalnealaldkvgln 414
Cdd:PTZ00121 1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA-------------- 1446

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  415 QQLLQLEEENQSVCSRMEAAEQARNALQVDlAEAEKRREALWEKNTHLEAQlQKAEEAGAELQADLRDIQEEKEEIQKKL 494
Cdd:PTZ00121 1447 DEAKKKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAK-KKADEAKKAAEAKKKADEAKKAEEAKKA 1524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  495 SESRHQQEAATTQLEQLHQEAKRQEEVLA----RAVQEKEALVREKAALEVRLQAVERdrqdlAEQLQGLSSAKELLESS 570
Cdd:PTZ00121 1525 DEAKKAEEAKKADEAKKAEEKKKADELKKaeelKKAEEKKKAEEAKKAEEDKNMALRK-----AEEAKKAEEARIEEVMK 1599

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  571 LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHE 650
Cdd:PTZ00121 1600 LYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  651 KEVNQLREKWEKERSWHQQELAKALESLEREKME-----LEMRLKEQQTEMEAIQAQR--EEERTQAESA---------L 714
Cdd:PTZ00121 1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEekkkaEELKKAEEENKIKAEEAKKeaEEDKKKAEEAkkdeeekkkI 1759

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  715 CQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETT----GILQTQLQEAQRELKEAARQHRDDLA 790
Cdd:PTZ00121 1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANiiegGKEGNLVINDSKEMEDSAIKEVADSK 1839

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768015747  791 ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK-ELERE 851
Cdd:PTZ00121 1840 NMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKdDIERE 1901
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 226-937 1.23e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 1.23e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   226 EEGKALRQRLQK-----LTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLE----VLEQEAWRLRRVNVELQL 296
Cdd:TIGR02169  211 ERYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEeieqLLEELNKKIKDLGEEEQL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   297 QGDSAQGQKEEQQEELHLAVRERERLQEmlmGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIA 376
Cdd:TIGR02169  291 RVKEKIGELEAEIASLERSIAEKERELE---DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   377 ELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALW 456
Cdd:TIGR02169  368 DLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   457 EKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEA---KRQEEVLARAVQEKEALV 533
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggRAVEEVLKASIQGVHGTV 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   534 RE--------KAALEV----RLQAVERDRQDLAEQLQGLSSAKEL-----LESSLFEAQQQNSVIEVTKGQLEVQIQTVT 596
Cdd:TIGR02169  528 AQlgsvgeryATAIEVaagnRLNNVVVEDDAVAKEAIELLKRRKAgratfLPLNKMRDERRDLSILSEDGVIGFAVDLVE 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   597 QAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE---QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQ-QELA 672
Cdd:TIGR02169  608 FDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERlEGLK 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   673 KALESLEREKMELEMRLKEQQTEMEAiqAQREEERTQAESALCQMQLETEKERVSLLETLLQ-TQKELADASQQLERLR- 750
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSD--ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSsLEQEIENVKSELKELEa 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   751 --QDMKVQKLKEQETTG-----ILQTQLQEAQRELKEAARQHRDDLAALQE---ESSSLLQDKMDLQKQVEDLKSQLVAQ 820
Cdd:TIGR02169  766 riEELEEDLHKLEEALNdlearLSHSRIPEIQAELSKLEEEVSRIEARLREieqKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   821 DDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 900
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 768015747   901 MELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLR 937
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1581-2117 1.69e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 1.69e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1581 LQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQ 1660
Cdd:COG1196   205 LERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1661 DHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQEL 1740
Cdd:COG1196   285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1741 EALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQ 1820
Cdd:COG1196   365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1821 EGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLT 1900
Cdd:COG1196   445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1901 LAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQ 1980
Cdd:COG1196   525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1981 TKASVsSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDG 2060
Cdd:COG1196   605 ASDLR-EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747 2061 MEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQ 2117
Cdd:COG1196   684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
PTZ00121 PTZ00121
MAEBL; Provisional
 434-1288 2.22e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 73.25  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  434 AEQARNALQVDLAEAEKRREALweknthleaqlQKAEEAgaelqadlRDIQE-EKEEIQKKLSESRHQQEAATTQLEQLH 512
Cdd:PTZ00121 1100 AEEAKKTETGKAEEARKAEEAK-----------KKAEDA--------RKAEEaRKAEDARKAEEARKAEDAKRVEIARKA 1160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  513 QEAKRQEEvlARAVQEKEALVREKAALEVRlqaverdrqdLAEQLQGLSSAKELLESSLFEAQQQnsVIEVTKGQLEVQI 592
Cdd:PTZ00121 1161 EDARKAEE--ARKAEDAKKAEAARKAEEVR----------KAEELRKAEDARKAEAARKAEEERK--AEEARKAEDAKKA 1226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  593 QTVTQAKEVIQGEVRCLKLE---LDTERSQAEQERDA--AARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwh 667
Cdd:PTZ00121 1227 EAVKKAEEAKKDAEEAKKAEeerNNEEIRKFEEARMAhfARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA-- 1304

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  668 qQELAKALESlEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSlletllQTQKELADASQQLE 747
Cdd:PTZ00121 1305 -DEAKKKAEE-AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA------EEKAEAAEKKKEEA 1376

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  748 RLRQDMKVQKLKEQETTGILQTQLQEAQREL-----KEAARQHRDDLAALQEE--SSSLLQDKMDLQKQVEDLKSQLvaq 820
Cdd:PTZ00121 1377 KKKADAAKKKAEEKKKADEAKKKAEEDKKKAdelkkAAAAKKKADEAKKKAEEkkKADEAKKKAEEAKKADEAKKKA--- 1453

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  821 ddSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRllvlQEADSIRQQELSALRQDmqeaQGEQKELSAQ 900
Cdd:PTZ00121 1454 --EEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK----KKADEAKKAAEAKKKAD----EAKKAEEAKK 1523

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  901 MELLRQEVKEKEADFL--AQEAQLLEELEAShiteQQLRAslwAQEAKAAQlQLRLRSTESQLEALAAEQQPGNQAQAQA 978
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkAEEKKKADELKKA----EELKK---AEEKKKAE-EAKKAEEDKNMALRKAEEAKKAEEARIE 1595

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  979 QLASLYSALQQALGSVCESRPELSGGGDSAPSvwglepdqngARSLFKRGPLLTALSAEAVASAlhklhQDLWKTQQTRD 1058
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK----------AEEEKKKVEQLKKKEAEEKKKA-----EELKKAEEENK 1660

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1059 VLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQ 1138
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1139 GERellQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKAlQ 1218
Cdd:PTZ00121 1741 EDK---KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGK-E 1816

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1219 ENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLE 1288
Cdd:PTZ00121 1817 GNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEE 1886
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 720-1510 2.87e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.40  E-value: 2.87e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   720 ETEKERVSLLETLLQTQKELADASQQLERL-RQDMKVQKLKEqettgiLQTQLQEAQREL-KEAARQHRDDLAALQEESS 797
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKSLeRQAEKAERYKE------LKAELRELELALlVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   798 SLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQ 877
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   878 QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLlEELEASHITEQQLRASLwaqEAKAAQLQLRLRST 957
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL-EELEEQLETLRSKVAQL---ELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   958 ESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGggdsapsvwglepdqngarslfkrgpllTALSAE 1037
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEE----------------------------LQEELE 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1038 AVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTdteaeksqvhtELQDLQRQLSQNQEEKSKWEGKQNSLESELMELh 1117
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLD-----------SLERLQENLEGFSEGVKALLKNQSGLSGILGVL- 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1118 etmaslqsrlrrAELQRMEAQGERELLQAAKENLTA-QVEHLQAAVVEARAQASA----AGILEEDLRTARSALKLKNEE 1192
Cdd:TIGR02168  526 ------------SELISVDEGYEAAIEAALGGRLQAvVVENLNAAKKAIAFLKQNelgrVTFLPLDSIKGTEIQGNDREI 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1193 VESERERAQALQEQGELKVAQGKALQENLA--LLTQTLAE---------REEEVETLRGQIQE----LEKQREMQKAALE 1257
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLRKALSYLLGgvLVVDDLDNalelakklrPGYRIVTLDGDLVRpggvITGGSAKTNSSIL 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1258 LLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHlpmAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIE 1337
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRK---ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1338 SQRGQVQDLKKQLVTLECLALELEENHHKMEcqqKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHST 1417
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAE---AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1418 VLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRT---RQTKILEEDLEQIKLSLRERG 1494
Cdd:TIGR02168  828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAsleEALALLRSELEELSEELRELE 907

                          810
                   ....*....|....*.
gi 768015747  1495 RELTTQRQLMQERAEE 1510
Cdd:TIGR02168  908 SKRSELRRELEELREK 923
PTZ00121 PTZ00121
MAEBL; Provisional
 828-1595 6.14e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 71.71  E-value: 6.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  828 EQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQE 907
Cdd:PTZ00121 1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARK 1159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  908 VKEKEADFLAQEAQLLEELEASHITEQQLRASLW--AQEAKAAQLQLRLRSTESQLEALAAEQQPGNqaqaqaqlaslys 985
Cdd:PTZ00121 1160 AEDARKAEEARKAEDAKKAEAARKAEEVRKAEELrkAEDARKAEAARKAEEERKAEEARKAEDAKKA------------- 1226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  986 alqQALGSVCESRPelsgggdsapsvwglepDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVlrDQVQ 1065
Cdd:PTZ00121 1227 ---EAVKKAEEAKK-----------------DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA--DELK 1284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1066 KLEERLTDTEAEKSQVHTELQDLQRQlsqnQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQ 1145
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKK----AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1146 AAKENLTAQvehlQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLT 1225
Cdd:PTZ00121 1361 AAEEKAEAA----EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA 1436

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1226 QTLAEREEEVETLRGQIQELEKQREMQKAALELLSLD-LKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQER----EQK 1300
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADeAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKkkadEAK 1516

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1301 LTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLikelegq 1380
Cdd:PTZ00121 1517 KAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA------- 1589

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1381 rETQRVALTHLTLDLEERSQELQAQSsqihdlESHSTVLARELQeRDQEVKSQREQIEELQRQKEHLTQDLERRDQELML 1460
Cdd:PTZ00121 1590 -EEARIEEVMKLYEEEKKMKAEEAKK------AEEAKIKAEELK-KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1461 QKERIQVLEDQRTRQTKIL---EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEve 1537
Cdd:PTZ00121 1662 KAAEEAKKAEEDKKKAEEAkkaEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA-- 1739

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 768015747 1538 cqQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELK 1595
Cdd:PTZ00121 1740 --EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 42-569 1.09e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 1.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   42 AQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTEL 121
Cdd:COG1196   267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  122 MEHEASLsRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGsghensleldssifsQFDYQDADKALTLVRSVLTRRRQAVQ 201
Cdd:COG1196   347 EEAEEEL-EEAEAELAEAEEALLEAEAELAEAEEELEEL---------------AEELLEALRAAAELAAQLEELEEAEE 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  202 DLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLE 281
Cdd:COG1196   411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  282 QEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQ 361
Cdd:COG1196   491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAK 570

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  362 TEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNAL 441
Cdd:COG1196   571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  442 QVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEV 521
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 768015747  522 LARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLES 569
Cdd:COG1196   731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
350-943 2.26e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 69.30  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  350 SHLEGELLRQEQTEVTAALARAEQSIAELSSSentLKTEVADLRAAAVKLSALNEALAlDKVGLNQQLLQLEEENQSVCS 429
Cdd:PRK02224  190 DQLKAQIEEKEEKDLHERLNGLESELAELDEE---IERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  430 RMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLE 509
Cdd:PRK02224  266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  510 QLHQEAKRQEEvlaravqEKEALVREKAALEVRLQAVERDRQDLAEQLqglssakELLESSLFEAQQQNSVIEVTKGQLE 589
Cdd:PRK02224  346 SLREDADDLEE-------RAEELREEAAELESELEEAREAVEDRREEI-------EELEEEIEELRERFGDAPVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  590 VQIQTVTQAKEVIQGEVRCLKLELDTERsqaeqERDAAARQLAQAeqeGKTALEQQKAAHEKEVNQLREKWEKerswhQQ 669
Cdd:PRK02224  412 DFLEELREERDELREREAELEATLRTAR-----ERVEEAEALLEA---GKCPECGQPVEGSPHVETIEEDRER-----VE 478

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  670 ELAKALESLEREKMELEMRLkeqqtemeaiqaQREEERTQAESalcqmQLETEKERVSLLETLLQTQKELADA-SQQLER 748
Cdd:PRK02224  479 ELEAELEDLEEEVEEVEERL------------ERAEDLVEAED-----RIERLEERREDLEELIAERRETIEEkRERAEE 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  749 LRQDMKVQKLKEQETtgilqtqlQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE 828
Cdd:PRK02224  542 LRERAAELEAEAEEK--------REAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLRE 613

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  829 QEVQEKLRETQEYNRIQKELEREK-------ASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQM 901
Cdd:PRK02224  614 KREALAELNDERRERLAEKRERKReleaefdEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEEL 693

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 768015747  902 ELLRQEVKEKEADFLAQEAqLLEELEASHITEQQLRASLWAQ 943
Cdd:PRK02224  694 EELRERREALENRVEALEA-LYDEAEELESMYGDLRAELRQR 734
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 254-964 5.31e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 5.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   254 GEVDSLSKERELLQKAREELRQQLEVLEQE---AWRLRRVNVELQ-LQGDSAQGQKEEQQEELHLAVRERERLQEMLMGL 329
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRRErekAERYQALLKEKReYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   330 EAKQSESLSELITLREALESSHLE-GELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALAL 408
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   409 DKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNthleaqlqkaeeagAELQADLRDIQEEKE 488
Cdd:TIGR02169  337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL--------------KDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   489 EIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLE 568
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   569 SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCL-----KLELDTERSQAEQERDAAAR-------------- 629
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaQLGSVGERYATAIEVAAGNRlnnvvveddavake 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   630 --QLAQAEQEGK-TALEQQK-AAHEKEVNQLRE---------------KWEKERSW--------HQQELAKAL------- 675
Cdd:TIGR02169  563 aiELLKRRKAGRaTFLPLNKmRDERRDLSILSEdgvigfavdlvefdpKYEPAFKYvfgdtlvvEDIEAARRLmgkyrmv 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   676 ----ESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLL-QTQKELADASQQLERLR 750
Cdd:TIGR02169  643 tlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLdELSQELSDASRKIGEIE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   751 QDMKvQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQ-----DDSQR 825
Cdd:TIGR02169  723 KEIE-QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELS 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   826 LVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLR 905
Cdd:TIGR02169  802 KLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE 881

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747   906 QEVKEKEADFLAQEAQlleeLEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEAL 964
Cdd:TIGR02169  882 SRLGDLKKERDELEAQ----LRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 607-1470 1.29e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 67.30  E-value: 1.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   607 RCLKLELDTERSQAEQERDAAaRQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELE 686
Cdd:pfam02463  190 IDLEELKLQELKLKEQAKKAL-EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   687 MRLKEQQTEMEAIQAQREEertqaesalcQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGI 766
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEE----------LKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   767 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQ-VEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQ 845
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLeSERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   846 KELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQmELLRQEVKEKEADFLAQEAQLLEE 925
Cdd:pfam02463  419 DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL-LKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   926 LEAShitEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG 1005
Cdd:pfam02463  498 RSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1006 DSAPSVWGLEPDQNGARSLFKRGPLLTALSA----EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQV 1081
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLaqldKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1082 HTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAA 1161
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1162 VVEARAQASAAGILEEDLrTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1241
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEE-EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1242 IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKcrsvLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNV 1321
Cdd:pfam02463  814 AELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE----ELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1322 LEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALEleenhHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQE 1401
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA-----EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  1402 LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLED 1470
Cdd:pfam02463  965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGW 1033
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1061-1567 1.29e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.99  E-value: 1.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1061 RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRlrraelqRMEAQGE 1140
Cdd:PRK02224  229 REQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEE-------RDDLLAE 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1141 RELLQAAKENLTAQVEHLQAAVVEaraqasaagiLEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1220
Cdd:PRK02224  302 AGLDDADAEAVEARREELEDRDEE----------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESE 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1221 LALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSldlkkrnqevdlqqeqiQELEKCRSVLEHLPMAVQEREQK 1300
Cdd:PRK02224  372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE-----------------DFLEELREERDELREREAELEAT 434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1301 LTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEgQ 1380
Cdd:PRK02224  435 LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIE-R 513

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1381 RETQRVALTHLtldLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQkehlTQDLERRDQELml 1460
Cdd:PRK02224  514 LEERREDLEEL---IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREE----VAELNSKLAEL-- 584

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1461 qKERIQVLEDQRTRQTKIleEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGpskaqrgslehmklilRDKEKEVECQQ 1540
Cdd:PRK02224  585 -KERIESLERIRTLLAAI--ADAEDEIERLREKREALAELNDERRERLAEKRE----------------RKRELEAEFDE 645

                         490       500
                  ....*....|....*....|....*..
gi 768015747 1541 EHIHELQELKDQLEQQLQGLHRKVGET 1567
Cdd:PRK02224  646 ARIEEAREDKERAEEYLEQVEEKLDEL 672
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1365-2080 3.13e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 3.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1365 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQK 1444
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1445 EHLTQDLERRDQELMLQKERIQVLEDQRTRqtkiLEEDLEQIKLSLRERGRELTTQRQLMQERAEEGkgpsKAQRGSLEH 1524
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEE----LEAELEELESRLEELEEQLETLRSKVAQLELQI----ASLNNEIER 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1525 MKLILRDKEKEVECQQEHIHELqeLKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLD 1604
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEEL--LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1605 EAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD------------------------ALQGALEQAHMTLKERHGELQ 1660
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilgvlselisvdegyeaaieaALGGRLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1661 DHKEQARrleeelaVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQEL 1740
Cdd:TIGR02168  563 AFLKQNE-------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1741 EALRAESQSSR--HQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 1818
Cdd:TIGR02168  636 ELAKKLRPGYRivTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1819 IQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQ 1898
Cdd:TIGR02168  716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1899 LTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQ-SLKLDSLEPRLQR------ELERLQAALRQTEAREIEWREKA 1971
Cdd:TIGR02168  796 EELKALREALDELRAELTLLNEEAANLRERLESLERRiAATERRLEDLEEQieelseDIESLAAEIEELEELIEELESEL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1972 QDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAE--LGSRGEQGVQLGEV 2049
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnlQERLSEEYSLTLEE 955

                          730       740       750
                   ....*....|....*....|....*....|.
gi 768015747  2050 sgVEAEPSPDGMEKQSWRQRLEHLQQAVARL 2080
Cdd:TIGR02168  956 --AEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 217-570 3.81e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 3.81e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   217 LQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQL 296
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   297 QGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIA 376
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   377 ELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALW 456
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR 921

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   457 EKNTHLEAQLQKAEEAGAELQADLRDIQE-EKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEkealvre 535
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEE------- 994

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 768015747   536 kaalevrLQAVERDRQDLAEQLQGLSSAKELLESS 570
Cdd:TIGR02168  995 -------YEELKERYDFLTAQKEDLTEAKETLEEA 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 42-553 5.27e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 5.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   42 AQLLLLLAKTQELEKEAHERSQELIQLKSqgdlEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILEtnhtEL 121
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEE----RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE----AE 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  122 MEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSsifsqfdyQDADKALTLVRSVLTRRRQAVQ 201
Cdd:COG1196   360 LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--------EALLERLERLEEELEELEEALA 431

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  202 DLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQ----L 277
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFlegvK 511

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  278 EVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELL 357
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA 591

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  358 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEAlaldkVGLNQQLLQLEEENQSVCSRMEAAEQA 437
Cdd:COG1196   592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA-----VTLAGRLREVTLEGEGGSAGGSLTGGS 666

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  438 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAattQLEQLHQEAKR 517
Cdd:COG1196   667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA---EREELLEELLE 743

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 768015747  518 QEEVLARAVQEKEALVREKAALEVRLQAVERDRQDL 553
Cdd:COG1196   744 EEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 180-511 7.11e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 7.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   180 QDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSL 259
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   260 SKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE 339
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   340 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQ 419
Cdd:TIGR02168  861 IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   420 LeeenqsvcsrmeaAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 499
Cdd:TIGR02168  941 L-------------QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTA 1007

                          330
                   ....*....|..
gi 768015747   500 QQEAATTQLEQL 511
Cdd:TIGR02168 1008 QKEDLTEAKETL 1019
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
430-967 7.33e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 7.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  430 RMEAAEQARNALQvDLAEAEKRREALWEKNTHLEA-----QLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAA 504
Cdd:COG4913   243 ALEDAREQIELLE-PIRELAERYAAARERLAELEYlraalRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  505 TTQLEQLHQEakrqeeVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQnsvievt 584
Cdd:COG4913   322 REELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAE------- 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  585 kgqlevqiqtVTQAKEVIQGEVRclklELDTERSQAEQERDAAARQLAQAEQEgKTALEQQKAAHEKEVNQLREKW---- 660
Cdd:COG4913   389 ----------AAALLEALEEELE----ALEEALAEAEAALRDLRRELRELEAE-IASLERRKSNIPARLLALRDALaeal 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  661 -----------------EKERSWH-----------------QQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEE 706
Cdd:COG4913   454 gldeaelpfvgelievrPEEERWRgaiervlggfaltllvpPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  707 RTQAEsalcqmQLETEKERVS-LLETLLQTQKELA--DASQQLERLRQDMKVQ-KLKEQETTGILQTQLQEAQREL--KE 780
Cdd:COG4913   534 DSLAG------KLDFKPHPFRaWLEAELGRRFDYVcvDSPEELRRHPRAITRAgQVKGNGTRHEKDDRRRIRSRYVlgFD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  781 AARQhrddLAALQEESSSLLQDKMDLQKQVEDLKSQLvAQDDSQRLVEQEVQEKLRETQEYNRIQKE---LEREKASLTL 857
Cdd:COG4913   608 NRAK----LAALEAELAELEEELAEAEERLEALEAEL-DALQERREALQRLAEYSWDEIDVASAEREiaeLEAELERLDA 682

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  858 S---LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQ 934
Cdd:COG4913   683 SsddLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762

                         570       580       590
                  ....*....|....*....|....*....|...
gi 768015747  935 QLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 967
Cdd:COG4913   763 VERELRENLEERIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
332-866 8.46e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 8.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  332 KQSESLSELITLREALESSHLEGELLRQEQTevTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKV 411
Cdd:COG4913   249 EQIELLEPIRELAERYAAARERLAELEYLRA--ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  412 GLNQQLLQLEEEnqsvcsRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQ 491
Cdd:COG4913   327 ELEAQIRGNGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEEL 400

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  492 KKLSESRHQQEAATTQLEQLHQEAKrqeevlaravQEKEALVREKAALEVRLQAVerdRQDLAEQLqGLSSAK-----EL 566
Cdd:COG4913   401 EALEEALAEAEAALRDLRRELRELE----------AEIASLERRKSNIPARLLAL---RDALAEAL-GLDEAElpfvgEL 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  567 LESSLFEAQQQNSV------------------------IEVTKGQLEVQIQ---TVTQAKEVIQGEVRCLKLELDTERSQ 619
Cdd:COG4913   467 IEVRPEEERWRGAIervlggfaltllvppehyaaalrwVNRLHLRGRLVYErvrTGLPDPERPRLDPDSLAGKLDFKPHP 546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  620 AeqeRDAAARQLAQAEQEGKTALEQQKAAHEK------EVNQLREKWEKERSWHQQEL-------AKALESLEREKMELE 686
Cdd:COG4913   547 F---RAWLEAELGRRFDYVCVDSPEELRRHPRaitragQVKGNGTRHEKDDRRRIRSRyvlgfdnRAKLAALEAELAELE 623

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  687 MRLKEQQTEMEAIQAQREEERTQAEsaLCQMQLETEKERVSlletLLQTQKELADASQQLERLRQDMkvQKLKEqettgi 766
Cdd:COG4913   624 EELAEAEERLEALEAELDALQERRE--ALQRLAEYSWDEID----VASAEREIAELEAELERLDASS--DDLAA------ 689

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  767 LQTQLQEAQRELKEAarqhRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL-VEQEVQEKLRETQE---YN 842
Cdd:COG4913   690 LEEQLEELEAELEEL----EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGdavER 765

                         570       580
                  ....*....|....*....|....
gi 768015747  843 RIQKELEREKASLTLSLMEKEQRL 866
Cdd:COG4913   766 ELRENLEERIDALRARLNRAEEEL 789
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1178-1697 1.15e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.91  E-value: 1.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1178 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALL-------TQTLAEREEEVETLRGQIQELEKQRE 1250
Cdd:PRK02224  210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLeaeiedlRETIAETEREREELAEEVRDLRERLE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1251 MQKAALELLSLDLKKRNQEVDLQQEQIQELEK----CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQL 1326
Cdd:PRK02224  290 ELEEERDDLLAEAGLDDADAEAVEARREELEDrdeeLRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1327 LELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE----LEGQRETQRVALTHLTLDLEERSQEL 1402
Cdd:PRK02224  370 SELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREerdeLREREAELEATLRTARERVEEAEALL 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1403 QAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ------ELMLQKERIQVLEDQRTRQT 1476
Cdd:PRK02224  450 EAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDlveaedRIERLEERREDLEELIAERR 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1477 KILEEDLEQIKlSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEcQQEHIHELQELKDQLEQQ 1556
Cdd:PRK02224  530 ETIEEKRERAE-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTLLAAIADAEDE 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1557 LQGLHRKVGETSLLLSQReqeivvlQQQLQEAREQ-GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVK 1635
Cdd:PRK02224  608 IERLREKREALAELNDER-------RERLAEKRERkRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQ 680

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768015747 1636 EKADALQGALEQAHmTLKERHGELQDHKEQARRLEEElavegrrVQALEEVLGDLRAESREQ 1697
Cdd:PRK02224  681 AEIGAVENELEELE-ELRERREALENRVEALEALYDE-------AEELESMYGDLRAELRQR 734
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
196-686 1.30e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.52  E-value: 1.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  196 RRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRq 275
Cdd:PRK02224  249 RREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELR- 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  276 qlEVLEQEAWRLRRVNVELQLQGDSAQGQKEeqqeelhlavrERERLQEMLMGLEAKQSESLSELITLREALESSHLEGE 355
Cdd:PRK02224  328 --DRLEECRVAAQAHNEEAESLREDADDLEE-----------RAEELREEAAELESELEEAREAVEDRREEIEELEEEIE 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  356 LLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKL-SALNEALALDKVGLNQQLLQLEEENQSVCSRMEAA 434
Cdd:PRK02224  395 ELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTArERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDR 474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  435 EQarnalqvdLAEAEKRREALWEKNTHLEAQLQKAEEAgAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQE 514
Cdd:PRK02224  475 ER--------VEELEAELEDLEEEVEEVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRER 545

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  515 AKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLssakELLESSLFEAQQQNSVIEVTKGQLEVQIQT 594
Cdd:PRK02224  546 AAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL----ERIRTLLAAIADAEDEIERLREKREALAEL 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  595 VTQAKEVIQGE---VRCLKLELDTER-SQAEQERDAAARQLAQAE------QEGKTALEQQKAAHEKEVNQLREKweKER 664
Cdd:PRK02224  622 NDERRERLAEKrerKRELEAEFDEARiEEAREDKERAEEYLEQVEekldelREERDDLQAEIGAVENELEELEEL--RER 699

                         490       500
                  ....*....|....*....|..
gi 768015747  665 SWHQQELAKALESLEREKMELE 686
Cdd:PRK02224  700 REALENRVEALEALYDEAEELE 721
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1397-2110 6.59e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 6.59e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1397 ERSQELQAQSSQIHDLESHstVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQT 1476
Cdd:TIGR02168  210 EKAERYKELKAELRELELA--LLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1477 KILEE------DLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELK 1550
Cdd:TIGR02168  288 KELYAlaneisRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1551 DQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQgelKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQ 1630
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR---LERLEDRRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1631 EERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAE 1710
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1711 QAQEHEVETR-------ALQDSwlqAQAVLKERDQE-LEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1782
Cdd:TIGR02168  525 LSELISVDEGyeaaieaALGGR---LQAVVVENLNAaKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1783 LEQAELSRSLEASTATLQA---------SLDACQAHSRQLEEALRI--QEGE-IQDQDLRYQEDVQQLQQALAQRDEELR 1850
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYllggvlvvdDLDNALELAKKLRPGYRIvtLDGDlVRPGGVITGGSAKTNSSILERRREIEE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1851 HQQEREQLLEKSLAQRVQENMIQEKQNLGQEReeeeirglhqsVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTS 1930
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEE-----------LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1931 PMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQ 2010
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  2011 DELELTRRALEkerlhspgaTSTAELGSRGEQGVQLgEVSGVEAEPSPDGMEKQswrqrLEHLQQAVARLEIDRSRLQRH 2090
Cdd:TIGR02168  831 RRIAATERRLE---------DLEEQIEELSEDIESL-AAEIEELEELIEELESE-----LEALLNERASLEEALALLRSE 895

                          730       740
                   ....*....|....*....|....
gi 768015747  2091 NVQLRSTLEQVERE----RRKLKR 2110
Cdd:TIGR02168  896 LEELSEELRELESKrselRRELEE 919
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
178-658 7.17e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 7.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  178 DYQDADKALTLVRSVLT-----RRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVD- 251
Cdd:COG4913   263 RYAAARERLAELEYLRAalrlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEq 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  252 LQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAV-----------RERE 320
Cdd:COG4913   343 LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALaeaeaalrdlrRELR 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  321 RLQEMLMGLEAKQSESLSELITLREALESsHLE---------GELL--RQEQTEVTAALARAeqsiaeLSSSENTLKTEV 389
Cdd:COG4913   423 ELEAEIASLERRKSNIPARLLALRDALAE-ALGldeaelpfvGELIevRPEEERWRGAIERV------LGGFALTLLVPP 495

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  390 ADLRAAAVKLSALNEALALD--KVGLNQQLLQLEE-ENQSVCSRMEAAE------------QARNALQVDLAEAEKR--- 451
Cdd:COG4913   496 EHYAAALRWVNRLHLRGRLVyeRVRTGLPDPERPRlDPDSLAGKLDFKPhpfrawleaelgRRFDYVCVDSPEELRRhpr 575

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  452 ----------REALWEKNTHLEAQLQ-----KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAK 516
Cdd:COG4913   576 aitragqvkgNGTRHEKDDRRRIRSRyvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE 655

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  517 RQEEVLARAvqekeALVREKAALEVRLQAVERDRQDLA---EQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQ 593
Cdd:COG4913   656 YSWDEIDVA-----SAEREIAELEAELERLDASSDDLAaleEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD 730

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  594 TVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE 658
Cdd:COG4913   731 ELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 429-1249 7.72e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   429 SRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDI-QEEKEEIQKKLSESRHQQEAATTQ 507
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERS 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   508 LEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQ 587
Cdd:TIGR02169  310 IAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   588 LEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQ--AEQEGKTALEQQKAAHEKEVNQLREKWEKERs 665
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYE- 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   666 whqqelaKALESLEREKMELEMRLKEQQTEMEAIQAQREE-ERTQAESALCQMQLETEKERV-SLLETLLQTQKELADAS 743
Cdd:TIGR02169  469 -------QELYDLKEEYDRVEKELSKLQRELAEAEAQARAsEERVRGGRAVEEVLKASIQGVhGTVAQLGSVGERYATAI 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   744 QQLERLRQDMKVQKLKEQETTGILQTQLQEAQR----ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVED-----LK 814
Cdd:TIGR02169  542 EVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafkyvFG 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   815 SQLVAQD--------DSQRLV--EQEVQEK---------------------LRETQEYNRIQKELEREKASLTLSLMEKE 863
Cdd:TIGR02169  622 DTLVVEDieaarrlmGKYRMVtlEGELFEKsgamtggsraprggilfsrsePAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   864 QRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEadflaqeaqllEELEASHITEQQLRASLWAQ 943
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE-----------QEIENVKSELKELEARIEEL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   944 EAKAAQLQLRLRSTESQLealaaeqqpgnqaqaqaqLASLYSALQQALGSVCESRPELSGggdsapsvwglepdqngars 1023
Cdd:TIGR02169  771 EEDLHKLEEALNDLEARL------------------SHSRIPEIQAELSKLEEEVSRIEA-------------------- 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1024 lfkrgplltalSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWE 1103
Cdd:TIGR02169  813 -----------RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1104 GKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEdlrtar 1183
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED------ 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 768015747  1184 saLKLKNEEVEserERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQR 1249
Cdd:TIGR02169  956 --VQAELQRVE---EEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 413-737 8.98e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 8.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   413 LNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQK 492
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA 786

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   493 KLSESRHQQeaATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLF 572
Cdd:TIGR02169  787 RLSHSRIPE--IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   573 EAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEqegktALEQQKAAHEKE 652
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE-----ALEEELSEIEDP 939

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   653 VNQLREKWEKERSWHQqeLAKALESLEREKMELEmrlkeqQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETL 732
Cdd:TIGR02169  940 KGEDEEIPEEELSLED--VQAELQRVEEEIRALE------PVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011


                   ....*
gi 768015747   733 LQTQK 737
Cdd:TIGR02169 1012 YEKKK 1016
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 322-867 9.03e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.90  E-value: 9.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   322 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLrQEQTEVTAALARAEQSI--AELSSSENTLKTEVADLRAAAVKL 399
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSI-QSQLEIIQEQARNQNSMymRQLSDLESTVSQLRSELREAKRMY 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   400 SALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQAD 479
Cdd:pfam15921  341 EDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   480 LRDIQEEKEEIQKKL----SESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL---VREKAALEVRLQAVERDRQD 552
Cdd:pfam15921  421 LDDRNMEVQRLEALLkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLrkvVEELTAKKMTLESSERTVSD 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   553 LAEQLQGLSSAkelLESSLFEAQQQNSVIEVTKGQLEvQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLA 632
Cdd:pfam15921  501 LTASLQEKERA---IEATNAEITKLRSRVDLKLQELQ-HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   633 QAEQEGKTA--LEQQKAAHEKEVNqlrekwekERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIqaqreeerTQA 710
Cdd:pfam15921  577 LVGQHGRTAgaMQVEKAQLEKEIN--------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKL--------VNA 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   711 ESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKeaarQHRDDLA 790
Cdd:pfam15921  641 GSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE----QTRNTLK 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   791 ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEV----QEKLRETQEYNRIQKEL-----EREKASLTLSLME 861
Cdd:pfam15921  717 SMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnanKEKHFLKEEKNKLSQELstvatEKNKMAGELEVLR 796


                   ....*.
gi 768015747   862 KEQRLL 867
Cdd:pfam15921  797 SQERRL 802
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1220-1673 1.02e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.80  E-value: 1.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1220 NLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELekcRSVLEHLPMAVQEREQ 1299
Cdd:TIGR04523  198 KLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQL---KDEQNKIKKQLSEKQK 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1300 KLTVQREQIRELEKdretQRNVLEHQLLELEKKDQM---------IESQRGQVQDLKKQLVTLECLALELEENHHKMEcq 1370
Cdd:TIGR04523  275 ELEQNNKKIKELEK----QLNQLKSEISDLNNQKEQdwnkelkseLKNQEKKLEEIQNQISQNNKIISQLNEQISQLK-- 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1371 qKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD 1450
Cdd:TIGR04523  349 -KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1451 LERRDQELMLQKERIQVLEDQRTRQTKILEedleqiklslrergrELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILR 1530
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIK---------------NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1531 DKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREqgELKEQSLQSQLDEAQRAL 1610
Cdd:TIGR04523  493 SKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF--ELKKENLEKEIDEKNKEI 570

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747  1611 AQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEEL 1673
Cdd:TIGR04523  571 EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII 633
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 200-855 1.08e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 1.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   200 VQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV 279
Cdd:TIGR02169  296 IGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   280 LEQEAWRLRRVNVELQLQGD-------SAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESShl 352
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEklkreinELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-- 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   353 EGEL----------------LRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALaldkVGLNQQ 416
Cdd:TIGR02169  454 EWKLeqlaadlskyeqelydLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV----HGTVAQ 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   417 LLQLEEENQSVCsrmEAAEQARNALQV--DLAEAEKRREALWEKNT------------HLEAQLQKAEEAGAELQA-DLR 481
Cdd:TIGR02169  530 LGSVGERYATAI---EVAAGNRLNNVVveDDAVAKEAIELLKRRKAgratflplnkmrDERRDLSILSEDGVIGFAvDLV 606

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   482 DIQEEKEEIQKKL-----------SESRHQQEAATTQLEQLHQE----------AKRQEEVLARAVQEKEALVREkaale 540
Cdd:TIGR02169  607 EFDPKYEPAFKYVfgdtlvvedieAARRLMGKYRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAELQRLRE----- 681

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   541 vRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ- 619
Cdd:TIGR02169  682 -RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSEl 760

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   620 -------AEQERDAAARQLAQAEQEGKTALE--QQKAAHEKEVNQLREKWEKErswhQQELAKALESLEREKMELEMRLK 690
Cdd:TIGR02169  761 keleariEELEEDLHKLEEALNDLEARLSHSriPEIQAELSKLEEEVSRIEAR----LREIEQKLNRLTLEKEYLEKEIQ 836

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   691 EQQTEMEAIQAQREEERTQAESALCQMQlETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQ 770
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKE-ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   771 -----LQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQ 845
Cdd:TIGR02169  916 rkrlsELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKR 995

                          730
                   ....*....|
gi 768015747   846 KELEREKASL 855
Cdd:TIGR02169  996 AKLEEERKAI 1005
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 199-910 1.59e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   199 AVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDL-QGEVDSLSKERELLQKAREELRQQL 277
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   278 EVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELL 357
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   358 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQA 437
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   438 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLE-----QLH 512
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvaagnRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   513 QEAKRQEEVLARAVQEKEA----------------------LVREKAALEVRLQAVERDRQ------------------D 552
Cdd:TIGR02169  551 NVVVEDDAVAKEAIELLKRrkagratflplnkmrderrdlsILSEDGVIGFAVDLVEFDPKyepafkyvfgdtlvvediE 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   553 LAEQLQG----LSSAKELLESS--LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLEL---DTERSQAEQE 623
Cdd:TIGR02169  631 AARRLMGkyrmVTLEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELrriENRLDELSQE 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   624 RDAAARQLAQAEQEGKtALEQQKAAHEKEVNQLREKwekerswhQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQR 703
Cdd:TIGR02169  711 LSDASRKIGEIEKEIE-QLEQEEEKLKERLEELEED--------LSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL 781

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   704 EE-ERTQAESALCQMQLET---EKERVSL----------LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQT 769
Cdd:TIGR02169  782 NDlEARLSHSRIPEIQAELsklEEEVSRIearlreieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNG 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   770 QLQEAQRELKEAA---RQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK 846
Cdd:TIGR02169  862 KKEELEEELEELEaalRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKG 941

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768015747   847 ELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALrQDMQEAQGEQKELSAQMELLRQEVKE 910
Cdd:TIGR02169  942 EDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAI-QEYEEVLKRLDELKEKRAKLEEERKA 1004
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
193-780 2.08e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 2.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  193 LTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEE--EGKALRQRLQKLTGER--DTLAGQTVDLQGEVDSLSKERELLQK 268
Cdd:COG4913   237 LERAHEALEDAREQIELLEPIRELAERYAAARERlaELEYLRAALRLWFAQRrlELLEAELEELRAELARLEAELERLEA 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  269 AREELRQQLEVLEQEAWRLRRVNVElqlqgdSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALE 348
Cdd:COG4913   317 RLDALREELDELEAQIRGNGGDRLE------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAA 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  349 SshlEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKL--------SALNEALALDKVGLN--QQLL 418
Cdd:COG4913   391 A---LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparllalrDALAEALGLDEAELPfvGELI 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  419 QLEEENQSvcSRMeAAEQA----RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKL 494
Cdd:COG4913   468 EVRPEEER--WRG-AIERVlggfALTLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKP 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  495 SESRHQQEAATTQ---------LEQLHQEAK-----------------------RQEEVL-ARAVQEKEALVREKAALEV 541
Cdd:COG4913   545 HPFRAWLEAELGRrfdyvcvdsPEELRRHPRaitragqvkgngtrhekddrrriRSRYVLgFDNRAKLAALEAELAELEE 624

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  542 RLQAVERDRQDLAEQLQGLSSAKELLE--SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQgevrclklELDTERSQ 619
Cdd:COG4913   625 ELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAELERLDASSDDLA--------ALEEQLEE 696

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  620 AEQERDAAARQLAQAEQEgKTALEQQKAAHEKEVNQLREKWE----KERSWHQQELAKALESLEREKMELEMRlKEQQTE 695
Cdd:COG4913   697 LEAELEELEEELDELKGE-IGRLEKELEQAEEELDELQDRLEaaedLARLELRALLEERFAAALGDAVERELR-ENLEER 774

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  696 MEAIQAQREEERTQAESALCQMQLETEKERVSL---LETLLQTQKELAD-ASQQLERLRQDMKvQKLKEQETTGI--LQT 769
Cdd:COG4913   775 IDALRARLNRAEEELERAMRAFNREWPAETADLdadLESLPEYLALLDRlEEDGLPEYEERFK-ELLNENSIEFVadLLS 853

                         650
                  ....*....|.
gi 768015747  770 QLQEAQRELKE 780
Cdd:COG4913   854 KLRRAIREIKE 864
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 432-660 2.25e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 2.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  432 EAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQL 511
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  512 HQEAKRQEEVLARAVQEKEALV----REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQ 587
Cdd:COG4942   103 KEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747  588 LEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKW 660
Cdd:COG4942   183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 317-932 2.65e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 59.35  E-value: 2.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   317 RERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAA 396
Cdd:pfam05483   85 KEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETC 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   397 VKLSALNEALALDKVGLNQQLLQLeeeNQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKaEEAGAEL 476
Cdd:pfam05483  165 ARSAEKTKKYEYEREETRQVYMDL---NNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKK-EINDKEK 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   477 QADLRDIQEEKEEiqKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQ-------AVERD 549
Cdd:pfam05483  241 QVSLLLIQITEKE--NKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQrsmstqkALEED 318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   550 RQDLAEQLQGLSSAKELLESSLFEAQQQNSVI----EVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERD 625
Cdd:pfam05483  319 LQIATKTICQLTEEKEAQMEELNKAKAAHSFVvtefEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTK 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   626 AAARQLAQAEQEGKTALEQQKAAHEkevNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREE 705
Cdd:pfam05483  399 FKNNKEVELEELKKILAEDEKLLDE---KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVED 475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   706 ERTQAESALCQMQLETEKERVSLLETLLQTQkELADASQQLERLRQDMKVQKLKEQETTGILQTqlqeaqreLKEAARQH 785
Cdd:pfam05483  476 LKTELEKEKLKNIELTAHCDKLLLENKELTQ-EASDMTLELKKHQEDIINCKKQEERMLKQIEN--------LEEKEMNL 546

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   786 RDDLAALQEEsssllqdkmdLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQR 865
Cdd:pfam05483  547 RDELESVREE----------FIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQE 616

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747   866 LLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHIT 932
Cdd:pfam05483  617 NKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAI 683
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 245-603 3.16e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 3.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   245 LAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRvnvelqlqgdsaqgqkeeQQEELHLAVRERERLQE 324
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ------------------ELSDASRKIGEIEKEIE 726

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   325 MLMGLEAKQSESLSELitlREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAavKLSALNE 404
Cdd:TIGR02169  727 QLEQEEEKLKERLEEL---EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP--EIQAELS 801

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   405 ALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQ 484
Cdd:TIGR02169  802 KLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE 881

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   485 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVER------DRQDLAEQLQ 558
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelSLEDVQAELQ 961

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 768015747   559 GLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQ 603
Cdd:TIGR02169  962 RVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1161-1385 3.23e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 3.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1161 AVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRG 1240
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1241 QIQELEKQREMQKAALELLSLDLKKRNQ----EVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRE 1316
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1317 TQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQ-QKLIKELEGQRETQR 1385
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEElEALIARLEAEAAAAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 44-289 4.02e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 4.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   44 LLLLLAKTQELEKEAHERSQELIQLKSQgdleKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELME 123
Cdd:COG4942     8 ALLLALAAAAQADAAAEAEAELEQLQQE----IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  124 HEASLSRNAQEEKLSLQQVIKDITQVMVEegdniAQGSGHENSLELdssIFSQFDYQDADKALTLVRSVLTRRRQAVQDL 203
Cdd:COG4942    84 ELAELEKEIAELRAELEAQKEELAELLRA-----LYRLGRQPPLAL---LLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  204 RQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQE 283
Cdd:COG4942   156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                  ....*.
gi 768015747  284 AWRLRR 289
Cdd:COG4942   236 AAAAAE 241
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 671-909 4.46e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 4.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  671 LAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQlETEKERVSLLETLLQTQKELADASQQLERLR 750
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELAELE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  751 QDMKVQKLKEQETTGILQTQLQEAQRelkeAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQE 830
Cdd:COG4942    90 KEIAELRAELEAQKEELAELLRALYR----LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  831 VQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 909
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
mukB PRK04863
chromosome partition protein MukB;
444-813 4.80e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 58.82  E-value: 4.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  444 DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLeQLHQEAKRQEEVLA 523
Cdd:PRK04863  273 DYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIE 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  524 RAVQEKEALV--------------REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLE 589
Cdd:PRK04863  352 RYQADLEELEerleeqnevveeadEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCG 431

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  590 VQIQTVTQAKEVIQgEVRCLKLELDTERSQAEQE---RDAAARQLAQAEQEGKTALEQ--QKAAHEKEVNQLREkWEKer 664
Cdd:PRK04863  432 LPDLTADNAEDWLE-EFQAKEQEATEELLSLEQKlsvAQAAHSQFEQAYQLVRKIAGEvsRSEAWDVARELLRR-LRE-- 507

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  665 swhQQELAKALESLEREKMELEMRLKEQQTEMEAIQ--AQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADA 742
Cdd:PRK04863  508 ---QRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAefCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMAL 584

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  743 SQQLERLRQDmkVQKLKEQETTGI--------LQTQLQEAQ---RELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 811
Cdd:PRK04863  585 RQQLEQLQAR--IQRLAARAPAWLaaqdalarLREQSGEEFedsQDVTEYMQQLLERERELTVERDELAARKQALDEEIE 662


                  ..
gi 768015747  812 DL 813
Cdd:PRK04863  663 RL 664
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1037-1753 5.56e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 5.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1037 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1116
Cdd:TIGR02169  332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1117 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESE 1196
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1197 RERAQALQEQGELKVAQGKALQENLalltqtlaerEEEVETLRGQIQELEKQREMQKAALEL-LSLDLKKRNQEVDLQQE 1275
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVL----------KASIQGVHGTVAQLGSVGERYATAIEVaAGNRLNNVVVEDDAVAK 561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1276 QIQELEKCRSVlehlpmavqEREQKLTVQREQIRELEKDRETQRNVLEHqLLELEKKDQMIESQRGQVqdLKKQLVTLEC 1355
Cdd:TIGR02169  562 EAIELLKRRKA---------GRATFLPLNKMRDERRDLSILSEDGVIGF-AVDLVEFDPKYEPAFKYV--FGDTLVVEDI 629

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1356 LALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQRE 1435
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1436 QIEELQRQKEHLTQDLERRDQELMLQKERIqvledqrtrqtKILEEDLEQIKLSLRERGRELTTQRQLMQERaEEGKGPS 1515
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERL-----------EELEEDLSSLEQEIENVKSELKELEARIEEL-EEDLHKL 777

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1516 KAQRGSLEHmklilRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQ---- 1591
Cdd:TIGR02169  778 EEALNDLEA-----RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQiksi 852

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1592 ------GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQ 1665
Cdd:TIGR02169  853 ekeienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1666 ARRLEEELAvEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEvETRALQDSWLQAQAVLKERDQELEALRA 1745
Cdd:TIGR02169  933 LSEIEDPKG-EDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYE-EVLKRLDELKEKRAKLEEERKAILERIE 1010


                   ....*...
gi 768015747  1746 ESQSSRHQ 1753
Cdd:TIGR02169 1011 EYEKKKRE 1018
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1076-1300 7.11e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 7.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1076 AEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQV 1155
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1156 EHLQAAVVEARAQASAAGileedlRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEV 1235
Cdd:COG4942   100 EAQKEELAELLRALYRLG------RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747 1236 ETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQK 1300
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1288-1914 8.39e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 8.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1288 EHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENH-HK 1366
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTvHE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1367 MECQQKLIKELEGQRETQRVALTHLTLDLEERSQEL--------QAQSSQIHDLESHSTV--------LARELQERDQEV 1430
Cdd:pfam15921  154 LEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIrsilvdfeEASGKKIYEHDSMSTMhfrslgsaISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1431 KSQREQIEELQRQKEHLTQDLERRdQELMLQKERIQVleDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEE 1510
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNK-IELLLQQHQDRI--EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1511 GKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHElqelkdQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEARE 1590
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIE------ELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLA 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1591 QGELKEQSLQSQLDEAQRaLAQRDQELEALQQEQQQAQGQEERVKEKADAL--------QGALEQAHMTLKERH------ 1656
Cdd:pfam15921  385 DLHKREKELSLEKEQNKR-LWDRDTGNSITIDHLRRELDDRNMEVQRLEALlkamksecQGQMERQMAAIQGKNeslekv 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1657 ----GELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCaeqaqeheVETRALQDSWLQAQAV 1732
Cdd:pfam15921  464 ssltAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEI--------TKLRSRVDLKLQELQH 535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1733 LKERDQELEALRAESQSSRHQEEAARARAEALQEalgkahaALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQ 1812
Cdd:pfam15921  536 LKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ-------QIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQE 608

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1813 LEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRH----QQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIR 1888
Cdd:pfam15921  609 FKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSE 688

                          650       660
                   ....*....|....*....|....*.
gi 768015747  1889 GLHQSVRELQLTLAQKEQEILELRET 1914
Cdd:pfam15921  689 EMETTTNKLKMQLKSAQSELEQTRNT 714
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1026-1255 8.85e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.70  E-value: 8.85e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1026 KRGPLLTALSAEAVASALHKLHQDLwktQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGK 1105
Cdd:COG4942     1 MRKLLLLALLLALAAAAQADAAAEA---EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1106 QNSLESELMELHETMASLQSRLRR---------AELQRMEAQGERELLQAAK---------ENLTAQVEHLQAAVVEARA 1167
Cdd:COG4942    78 LAALEAELAELEKEIAELRAELEAqkeelaellRALYRLGRQPPLALLLSPEdfldavrrlQYLKYLAPARREQAEELRA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1168 QASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQgkaLQENLALLTQTLAEREEEVETLRGQIQELEK 1247
Cdd:COG4942   158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEA 234


                  ....*...
gi 768015747 1248 QREMQKAA 1255
Cdd:COG4942   235 EAAAAAER 242
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 651-1509 9.16e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 57.67  E-value: 9.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   651 KEVNQLREKWEKERSWHQQELA-----KALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKER 725
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAgsrlkRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   726 VSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQhrddlaalQEESSSLLQDKMD 805
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE--------KKLQEEELKLLAK 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   806 LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRetqeynRIQKELEREKASL-------------TLSLMEKEQRLLVLQEA 872
Cdd:pfam02463  294 EEEELKSELLKLERRKVDDEEKLKESEKEKK------KAEKELKKEKEEIeelekelkeleikREAEEEEEEELEKLQEK 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   873 DSIRQQELSALRQDMQEAQGEQKELsAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQ-----QLRASLWAQEAKA 947
Cdd:pfam02463  368 LEQLEEELLAKKKLESERLSSAAKL-KEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEEleileEEEESIELKQGKL 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   948 AQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKR 1027
Cdd:pfam02463  447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1028 GPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQN 1107
Cdd:pfam02463  527 AHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLA 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1108 SLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASaagiLEEDLRTARSALK 1187
Cdd:pfam02463  607 QLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLS----ELTKELLEIQELQ 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1188 LKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRN 1267
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1268 QEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLK 1347
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1348 KQLVTLECLALELEENHHKMECQQKLIKELEGQR-ETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQER 1426
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEeELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEER 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1427 DQEVKSQREQIEELQRqKEHLTQDLERRDQE--LMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLM 1504
Cdd:pfam02463  923 IKEEAEILLKYEEEPE-ELLLEEADEKEKEEnnKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLE 1001


                   ....*
gi 768015747  1505 QERAE 1509
Cdd:pfam02463 1002 EEKKK 1006
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 449-1138 1.10e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.44  E-value: 1.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   449 EKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQE 528
Cdd:pfam15921  102 EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLS 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   529 KEALVREKAALEVRLQAVERDR----------------QDLAEQLQGLSSAKELLESSLFEAQQQnsvIEVTKGQLEVQI 592
Cdd:pfam15921  182 HEGVLQEIRSILVDFEEASGKKiyehdsmstmhfrslgSAISKILRELDTEISYLKGRIFPVEDQ---LEALKSESQNKI 258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   593 QTVTQAKeviQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREkWEKERSWHQQELA 672
Cdd:pfam15921  259 ELLLQQH---QDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSD-LESTVSQLRSELR 334

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   673 KALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQletekervSLLETLLQTQKELADASQQLERL--- 749
Cdd:pfam15921  335 EAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ--------KLLADLHKREKELSLEKEQNKRLwdr 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   750 -----------RQDMKVQKLKEQETTGILQTQLQEAQRELKE---AARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKS 815
Cdd:pfam15921  407 dtgnsitidhlRRELDDRNMEVQRLEALLKAMKSECQGQMERqmaAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTA 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   816 QLVAQDDSQRLVEQ---EVQEKLRETQEYNriqKELEREKASLTLSLMEKEQrllVLQEADSIR--QQELSALRQDMQEA 890
Cdd:pfam15921  487 KKMTLESSERTVSDltaSLQEKERAIEATN---AEITKLRSRVDLKLQELQH---LKNEGDHLRnvQTECEALKLQMAEK 560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   891 QGEQKELSAQMELLRQEVKE---KEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTEsqleaLAAE 967
Cdd:pfam15921  561 DKVIEILRQQIENMTQLVGQhgrTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE-----LEKV 635

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   968 QQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSV-------------------WGLEPDQNGARSLFKRG 1028
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLkrnfrnkseemetttnklkMQLKSAQSELEQTRNTL 715

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1029 PLLTALSAEAVASALHKLHQDLWKTQQTrDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNS 1108
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQI-DALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEV 794

                          730       740       750
                   ....*....|....*....|....*....|
gi 768015747  1109 LESELMELHETMASLQSRLRRAELQRMEAQ 1138
Cdd:pfam15921  795 LRSQERRLKEKVANMEVALDKASLQFAECQ 824
PTZ00121 PTZ00121
MAEBL; Provisional
 1062-1699 1.16e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1062 DQVQKLEERLTDTEAEKSQVHTELQDLQR-QLSQNQEEKSKWEGKQNSLE-SELMELHETmaslqSRLRRAELQRmEAQG 1139
Cdd:PTZ00121 1137 EDARKAEEARKAEDAKRVEIARKAEDARKaEEARKAEDAKKAEAARKAEEvRKAEELRKA-----EDARKAEAAR-KAEE 1210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1140 ERELLQAAKENLTAQVEHLQAaVVEARAQASAAGILEEDlRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQE 1219
Cdd:PTZ00121 1211 ERKAEEARKAEDAKKAEAVKK-AEEAKKDAEEAKKAEEE-RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1220 NLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELL--SLDLKKRNQEVDLQQE-QIQELEKCRSVLEHLPMAVQE 1296
Cdd:PTZ00121 1289 KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKkkADAAKKKAEEAKKAAEaAKAEAEAAADEAEAAEEKAEA 1368

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1297 REQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE 1376
Cdd:PTZ00121 1369 AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADE 1448

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1377 LEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQRE---QIEELQRQKEHLTQDLER 1453
Cdd:PTZ00121 1449 AKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEakkKADEAKKAEEAKKADEAK 1528

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1454 RDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQrgslehMKLILRDKE 1533
Cdd:PTZ00121 1529 KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR------IEEVMKLYE 1602

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1534 KEVECQQEHIHELQELKDQLEQQLQGlhRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRAlAQR 1613
Cdd:PTZ00121 1603 EEKKMKAEEAKKAEEAKIKAEELKKA--EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK-AEE 1679

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1614 DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK---EQARRLEEELAVEGRRVQALEEVLGDL 1690
Cdd:PTZ00121 1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKikaEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759


                  ....*....
gi 768015747 1691 RAESREQEK 1699
Cdd:PTZ00121 1760 AHLKKEEEK 1768
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
769-966 1.60e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  769 TQLQEAQRELKEAARQhRDDLAALQEESSSLLQDKMDLQKQvEDLKSQLVAQDDSQRLVEQEvQEKLRETQEYNRIQKEL 848
Cdd:COG4913   235 DDLERAHEALEDAREQ-IELLEPIRELAERYAAARERLAEL-EYLRAALRLWFAQRRLELLE-AELEELRAELARLEAEL 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  849 EREKASLTLSLMEKEQRLLVLQEADSIR----QQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLE 924
Cdd:COG4913   312 ERLEARLDALREELDELEAQIRGNGGDRleqlEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAA 391

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 768015747  925 ELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAA 966
Cdd:COG4913   392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 191-552 2.04e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 2.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   191 SVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGErdtlagqTVDLQGEVDSLSKERELLQKAR 270
Cdd:TIGR02169  667 LFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK-------IGEIEKEIEQLEQEEEKLKERL 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   271 EELRQQLEVLEQEAWRLRRVNVEL-----QLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLRE 345
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELearieELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQ 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   346 ALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQ 425
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   426 SVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELqADLRDIQEEKEEIQKKLSESRHQQEAAt 505
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAELQRVEEEIRALEPVNMLA- 977

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 768015747   506 tqLEQLHQEAKRQEEVlaraVQEKEALVREKAALEVRLQAVERDRQD 552
Cdd:TIGR02169  978 --IQEYEEVLKRLDEL----KEKRAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 49-399 2.30e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 2.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747    49 AKTQELEKEAHERSQELIQLKSQGDL---EKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHE 125
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEEleeELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   126 ASLSRNAQEEKLSLQQVIKDITQVMveegdniAQGSGHENSLELDSSIFSqfdyqDADKALTLVRSVLTRRRQAVQDLRQ 205
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELE-------AQIEQLKEELKALREALD-----ELRAELTLLNEEAANLRERLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   206 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAW 285
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   286 RLRRVNVELQLQ-GDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESshlegelLRQEQTEV 364
Cdd:TIGR02168  912 ELRRELEELREKlAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR-------LENKIKEL 984

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 768015747   365 TAALARAEQSIAELSSSENTLKTEVADLRAAAVKL 399
Cdd:TIGR02168  985 GPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETL 1019
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 653-937 3.56e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.51  E-value: 3.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   653 VNQLREKWEKERSWHQQELAKALESLEREKMELEMrlKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETL 732
Cdd:pfam17380  271 LNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEK--EEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   733 LQTQKELADASQQLERLRQD---MKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQ 809
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEeiaMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAE 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   810 VEDLKSQLVA--QDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDM 887
Cdd:pfam17380  429 QEEARQREVRrlEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAM 508

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 768015747   888 QEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLE-ELEASHITEQQLR 937
Cdd:pfam17380  509 IEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQqEMEERRRIQEQMR 559
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
65-576 3.82e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 3.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   65 LIQLKSQ-GDLEKAELQDRVTELSALLTQSQKQNEDYEK--------------MIKALRETVEILETNHTELMEHEASLS 129
Cdd:PRK02224  189 LDQLKAQiEEKEEKDLHERLNGLESELAELDEEIERYEEqreqaretrdeadeVLEEHEERREELETLEAEIEDLRETIA 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  130 rNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQfDYQDADKALTLVRSVLTRRRQAVQDLRQQLAG 209
Cdd:PRK02224  269 -ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEA-RREELEDRDEELRDRLEECRVAAQAHNEEAES 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  210 CQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRR 289
Cdd:PRK02224  347 LREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRE 426

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  290 VNVELQLQGDSAQGqkeeqqeelhlAVRERERLQEM----LMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVT 365
Cdd:PRK02224  427 REAELEATLRTARE-----------RVEEAEALLEAgkcpECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVE 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  366 AALARAEQSI---AELSSSENTLKT---EVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARN 439
Cdd:PRK02224  496 ERLERAEDLVeaeDRIERLEERREDleeLIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVA 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  440 ALQVDLAEAEKRREALwEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSE--SRHQQEAATTQ---LEQLHQE 514
Cdd:PRK02224  576 ELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEkrERKRELEAEFDearIEEARED 654

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  515 AKRQEEVLARAVQEKEALVREKAALEVRLQAVERD---RQDLAEQLQGLSSAKELLESSLFEAQQ 576
Cdd:PRK02224  655 KERAEEYLEQVEEKLDELREERDDLQAEIGAVENEleeLEELRERREALENRVEALEALYDEAEE 719
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1146-1697 6.69e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 6.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1146 AAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLT 1225
Cdd:PRK03918  186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1226 QTLAEREEEVETLRGQIQELEKQREMQKAALELlsldlkkrNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQR 1305
Cdd:PRK03918  266 ERIEELKKEIEELEEKVKELKELKEKAEEYIKL--------SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1306 EQIRELEKDRETQRNVLEhQLLELEKKDQMIESQRGQVQDLKKQLVTLEclaleleenhhkMECQQKLIKELEGQRETQR 1385
Cdd:PRK03918  338 ERLEELKKKLKELEKRLE-ELEERHELYEEAKAKKEELERLKKRLTGLT------------PEKLEKELEELEKAKEEIE 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1386 VALTHLTL---DLEERSQELQAQSSQIHDLESHSTVLARELQERDQ---------EVKSQREQIEELQRQKEHLTQDLER 1453
Cdd:PRK03918  405 EEISKITArigELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRkelleeytaELKRIEKELKEIEEKERKLRKELRE 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1454 RDQELMLQKERIQVLEdqRTRQTKILEEDLEQIKLslrERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKE 1533
Cdd:PRK03918  485 LEKVLKKESELIKLKE--LAEQLKELEEKLKKYNL---EELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1534 KEVECQQEHIHELQELKDQLE--------------QQLQGLHRKVGETSLL---LSQREQEIVVLQQQLQEAREQGELKE 1596
Cdd:PRK03918  560 ELEKKLDELEEELAELLKELEelgfesveeleerlKELEPFYNEYLELKDAekeLEREEKELKKLEEELDKAFEELAETE 639

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1597 ---QSLQSQLDEAQRALAQRDqeLEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE-E 1672
Cdd:PRK03918  640 krlEELRKELEELEKKYSEEE--YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKlE 717

                         570       580
                  ....*....|....*....|....*
gi 768015747 1673 LAVEgrRVQALEEVLGDLRAESREQ 1697
Cdd:PRK03918  718 KALE--RVEELREKVKKYKALLKER 740
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 612-733 1.37e-06

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 53.93  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  612 ELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQ--QELAKALESLEREKMELEMRL 689
Cdd:COG0542   415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEeiQELKEELEQRYGKIPELEKEL 494

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 768015747  690 KEQQTEMEAIQAQREEERTQAESA----------LCQMqLETEKERVSLLETLL 733
Cdd:COG0542   495 AELEEELAELAPLLREEVTEEDIAevvsrwtgipVGKL-LEGEREKLLNLEEEL 547
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 675-1314 1.59e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.69  E-value: 1.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   675 LESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMK 754
Cdd:pfam12128  260 LSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADI 339

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   755 VQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLlqdKMDLQKQVEDLKSQLVAQDdsqrlvEQEVQEK 834
Cdd:pfam12128  340 ETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKI---KEQNNRDIAGIKDKLAKIR------EARDRQL 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   835 LRETQEYNRIQKELEREKASLTLSLMEKEQRLlvlqeadSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEAD 914
Cdd:pfam12128  411 AVAEDDLQALESELREQLEAGKLEFNEEEYRL-------KSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   915 FLAQEAQLLEELEASHITEQQLRAsLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQqalgsv 994
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEA-LRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVIS------ 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   995 cesrPELSGGGDSAPSVWGLEPdqNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDT 1074
Cdd:pfam12128  557 ----PELLHRTDLDPEVWDGSV--GGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1075 EAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME-LHETMASLQSRLRR--AELQRMEAQGERELLQAAKENL 1151
Cdd:pfam12128  631 NGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSleAQLKQLDKKHQAWLEEQKEQKR 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1152 TAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAER 1231
Cdd:pfam12128  711 EARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVR 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1232 EEEV--------ETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLqqeQIQELEKCRSVLEHLPMAVQEREQKLTV 1303
Cdd:pfam12128  791 RQEVlryfdwyqETWLQRRPRLATQLSNIERAISELQQQLARLIADTKL---RRAKLEMERKASEKQQVRLSENLRGLRC 867

                          650
                   ....*....|.
gi 768015747  1304 QREQIRELEKD 1314
Cdd:pfam12128  868 EMSKLATLKED 878
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 193-407 1.66e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  193 LTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREE 272
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  273 LRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHL 352
Cdd:COG4942   102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  353 EgelLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALA 407
Cdd:COG4942   182 E---LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1041-1492 1.76e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1041 SALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEE-----------KSKWEGKQNSL 1109
Cdd:TIGR04523  197 LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQlnqlkdeqnkiKKQLSEKQKEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1110 ESELMELHETMASLQSrlRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALK-L 1188
Cdd:TIGR04523  277 EQNNKKIKELEKQLNQ--LKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTnS 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1189 KNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTlAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQ 1268
Cdd:TIGR04523  355 ESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQI-NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKE 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1269 EVDLQQEQIQELEKCRSVLEhlpMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKK 1348
Cdd:TIGR04523  434 TIIKNNSEIKDLTNQDSVKE---LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEE 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1349 QLVTLECLALELEENHHKMECQ----QKLIKELEGQRETQRVALTHltLDLEERSQELQAQSSQIHD----LESHSTVLA 1420
Cdd:TIGR04523  511 KVKDLTKKISSLKEKIEKLESEkkekESKISDLEDELNKDDFELKK--ENLEKEIDEKNKEIEELKQtqksLKKKQEEKQ 588

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768015747  1421 RELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQElmlqKERIQVLEDQRTRQTKILEEDLEQIKLSLRE 1492
Cdd:TIGR04523  589 ELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE----NEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1370-1613 2.39e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1370 QQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQ 1449
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1450 DLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIklslrerGRELTTQRQLMQERAEEGKGpskaqrgsLEHMKLIL 1529
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDA-------VRRLQYLKYLAPARREQAEE--------LRADLAEL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1530 RDKEKEVECQQEhihELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQgelkEQSLQSQLDEAQRA 1609
Cdd:COG4942   163 AALRAELEAERA---ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE----AEELEALIARLEAE 235


                  ....
gi 768015747 1610 LAQR 1613
Cdd:COG4942   236 AAAA 239
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1189-1701 2.49e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1189 KNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQ 1268
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1269 EVDLQQEQIQELEKCRSVLEHlpmAVQEREQKLTVQREQIRELEKDRE---TQRNVLEHQLLELEKKDQMIESQRGQVQ- 1344
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEK---QKKENKKNIDKFLTEIKKKEKELEklnNKYNDLKKQKEELENELNLLEKEKLNIQk 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1345 ---DLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAR 1421
Cdd:TIGR04523  188 nidKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1422 ELQERDQEVKSQREQIEELQRQKEHLTQDLERrdqelmLQKERIQVLedqrtrqTKILEEDLEQIKLSLRERGRELTTQR 1501
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQLKSEISD------LNNQKEQDW-------NKELKSELKNQEKKLEEIQNQISQNN 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1502 QLMQERAEEGKGPSKAQRGSLEHMKLI---LRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEI 1578
Cdd:TIGR04523  335 KIISQLNEQISQLKKELTNSESENSEKqreLEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1579 VVLQQQLQE-AREQGELKEQ--SLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKER 1655
Cdd:TIGR04523  415 KKLQQEKELlEKEIERLKETiiKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 768015747  1656 HGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKAL 1701
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKI 540
PTZ00121 PTZ00121
MAEBL; Provisional
 1422-2018 2.51e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 2.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1422 ELQERDQEVKSQRE--QIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKlSLRERGRELTT 1499
Cdd:PTZ00121 1179 EAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE-EERNNEEIRKF 1257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1500 QRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQlqglhRKVGETSLLLSQREQEIV 1579
Cdd:PTZ00121 1258 EEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA-----KKADEAKKKAEEAKKKAD 1332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1580 VLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE--KADALQGALEQAHMT---LKE 1654
Cdd:PTZ00121 1333 AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEkkKADEAKKKAEEDKKKadeLKK 1412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1655 RHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEV-----ETRALQDSWLQA 1729
Cdd:PTZ00121 1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAkkkaeEAKKADEAKKKA 1492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1730 QAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAH 1809
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA 1572

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1810 SRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQE--------REQLLEKSLAQRVQENMIQEKQNLGQE 1881
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEakikaeelKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1882 REEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPR----LQRELERLQAAL 1957
Cdd:PTZ00121 1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKkaeeLKKAEEENKIKA 1732

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747 1958 RQTEAREIEWREKAQDLAL------SLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRR 2018
Cdd:PTZ00121 1733 EEAKKEAEEDKKKAEEAKKdeeekkKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
464-797 2.79e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 52.21  E-value: 2.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  464 AQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRL 543
Cdd:COG4372    38 FELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEEL 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  544 QAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIqgevrclkleLDTERSQAEQE 623
Cdd:COG4372   118 EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQAL----------SEAEAEQALDE 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  624 RDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQR 703
Cdd:COG4372   188 LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAI 267

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  704 EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR 783
Cdd:COG4372   268 LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLL 347

                         330
                  ....*....|....
gi 768015747  784 QHRDDLAALQEESS 797
Cdd:COG4372   348 VGLLDNDVLELLSK 361
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 630-913 2.95e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.43  E-value: 2.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   630 QLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREK---MELEMRLKEQQTEMeAIQAQREEE 706
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARqaeMDRQAAIYAEQERM-AMERERELE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   707 RTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKV---QKLKEQETTGILQTQLQEAQRELKEAAR 783
Cdd:pfam17380  352 RIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAarkVKILEEERQRKIQQQKVEMEQIRAEQEE 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   784 QHRDDLAALQEESSSLL----QDKMDLQKQVEDLKSQ------------------LVAQDDSQRLVEQEVQEKLRETQEY 841
Cdd:pfam17380  432 ARQREVRRLEEERAREMervrLEEQERQQQVERLRQQeeerkrkklelekekrdrKRAEEQRRKILEKELEERKQAMIEE 511

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 768015747   842 NRIQKELEREKASLTLSLMEKEQRLLVLQE-ADSIRQQELSALRQDMQEAQGEQKELSA---QMELLRQEVKEKEA 913
Cdd:pfam17380  512 ERKRKLLEKEMEERQKAIYEEERRREAEEErRKQQEMEERRRIQEQMRKATEERSRLEAmerEREMMRQIVESEKA 587
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1077-1614 3.59e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 52.42  E-value: 3.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1077 EKSQVHTELQD-LQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRaELQRMEAQGERELLQAAKENltAQV 1155
Cdd:pfam05483  180 ETRQVYMDLNNnIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKK-EINDKEKQVSLLLIQITEKE--NKM 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1156 EHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEV 1235
Cdd:pfam05483  257 KDLTFLLEESRDKANQ---LEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1236 ETlrgQIQELEKQREMQkaALELLSLDLKKRNQEVDLQQEQiQELEKCRSVLEHLPMAVQEREQKLtvqrEQIRELEKDR 1315
Cdd:pfam05483  334 EA---QMEELNKAKAAH--SFVVTEFEATTCSLEELLRTEQ-QRLEKNEDQLKIITMELQKKSSEL----EEMTKFKNNK 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1316 ETQRNVLEHQLLElekkDQMIESQRGQVQDLKKQLVTLECLALELeenhhkMECQQKLIKELEGQRETQRVALTHLTLDL 1395
Cdd:pfam05483  404 EVELEELKKILAE----DEKLLDEKKQFEKIAEELKGKEQELIFL------LQAREKEIHDLEIQLTAIKTSEEHYLKEV 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1396 EERSQELQAQSSQIHDLESHSTVLARELQERDQEVKsqrEQIEELQRQKEHLTQDleRRDQELMLQKerIQVLEDQRTRq 1475
Cdd:pfam05483  474 EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEAS---DMTLELKKHQEDIINC--KKQEERMLKQ--IENLEEKEMN- 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1476 tkiLEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQ 1555
Cdd:pfam05483  546 ---LRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747  1556 QLQGLHRKVGETSLLLSQREQEIVVLQQQLQEA----REQGELKEQSLQSQLDEAQRALAQRD 1614
Cdd:pfam05483  623 KGSAENKQLNAYEIKVNKLELELASAKQKFEEIidnyQKEIEDKKISEEKLLEEVEKAKAIAD 685
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 469-698 3.99e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.99e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  469 AEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVER 548
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  549 DRQDLAEQLQGLSSAKELLESS---LFEAQQQNSVIEVTKGQLevqIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERD 625
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQpplALLLSPEDFLDAVRRLQY---LKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747  626 AAARQLAQAEQEgKTALEQQKAAHEKEVNQLREKwekerswhQQELAKALESLEREKMELEMRLKEQQTEMEA 698
Cdd:COG4942   175 ELEALLAELEEE-RAALEALKAERQKLLARLEKE--------LAELAAELAELQQEAEELEALIARLEAEAAA 238
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1373-1696 4.04e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 4.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1373 LIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLEshstvlaRELQERDQEVKSQREQIEELQRQKEHLTQDLE 1452
Cdd:TIGR02169  196 KRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALE-------RQKEAIERQLASLEEELEKLTEEISELEKRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1453 RRDQELMLQKERIQVL--EDQRTRQTKI--LEEDLEQIKLSLRERGRELttqrQLMQERAEEGKGPSKAQRGSLEHMKLI 1528
Cdd:TIGR02169  269 EIEQLLEELNKKIKDLgeEEQLRVKEKIgeLEAEIASLERSIAEKEREL----EDAEERLAKLEAEIDKLLAEIEELERE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1529 LRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIvvlqQQLQEAREQGELKEQSLQSQLDEAQR 1608
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL----EKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1609 ALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLG 1688
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500


                   ....*...
gi 768015747  1689 DLRAESRE 1696
Cdd:TIGR02169  501 ASEERVRG 508
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1434-1789 5.25e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 5.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1434 REQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEedleqIKLSLRERGRELTTQRQlmqERAEEGKG 1513
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKE-----LKAELRELELALLVLRL---EELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1514 PSKAQRGSLEHMKLILRDKEKEVECQ-QEHIHELQELKDQLEQQLQGLHRKVGETSLLlSQREQEIVVLQQQLQEAREQG 1592
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKlEELRLEVSELEEEIEELQKELYALANEISRL-EQQKQILRERLANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1593 ELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEE 1672
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1673 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQA-QEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSR 1751
Cdd:TIGR02168  402 IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 768015747  1752 HQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELS 1789
Cdd:TIGR02168  482 RELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLS 519
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 322-813 6.80e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.59  E-value: 6.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   322 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENtLKTEVADLRAAAVKLSA 401
Cdd:TIGR00606  575 LEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQD-EESDLERLKEEIEKSSK 653

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   402 LNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLR 481
Cdd:TIGR00606  654 QRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAP 733

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   482 DIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL------VREKAALEVRLQAVERDRQDLAE 555
Cdd:TIGR00606  734 GRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAkvcltdVTIMERFQMELKDVERKIAQQAA 813

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   556 QLQGLSSAKELLESSLFEAQQQNSVIEVTKgqlevQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 635
Cdd:TIGR00606  814 KLQGSDLDRTVQQVNQEKQEKQHELDTVVS-----KIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEE 888

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   636 QEGKTALEQQKAAHE-KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAL 714
Cdd:TIGR00606  889 QLVELSTEVQSLIREiKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGK 968

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   715 CQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQK-----LKEQETTGILQTQLQEAQRELKEAARQHRDDL 789
Cdd:TIGR00606  969 DDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKiqerwLQDNLTLRKRENELKEVEEELKQHLKEMGQMQ 1048

                          490       500
                   ....*....|....*....|....
gi 768015747   790 AALQEESSSLLQDKMDLQKQVEDL 813
Cdd:TIGR00606 1049 VLQMKQEHQKLEENIDLIKRNHVL 1072
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 768-967 7.16e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 7.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  768 QTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKE 847
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  848 LEREKASL--TLSLMEKEQRLLVLQEADSIRQ---------QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADfL 916
Cdd:COG4942   102 QKEELAELlrALYRLGRQPPLALLLSPEDFLDavrrlqylkYLAPARREQAEELRADLAELAALRAELEAERAELEAL-L 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 768015747  917 AQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 967
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1048-1382 7.94e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 50.67  E-value: 7.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1048 QDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRL 1127
Cdd:COG4372    31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1128 RRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQAsaagileEDLRTARSALKLKNEEVESERERAQALQEQG 1207
Cdd:COG4372   111 EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEEL-------KELEEQLESLQEELAALEQELQALSEAEAEQ 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1208 ELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVL 1287
Cdd:COG4372   184 ALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1288 EHLPMAVQEREQ-KLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHK 1366
Cdd:COG4372   264 ELAILVEKDTEEeELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLL 343

                         330
                  ....*....|....*.
gi 768015747 1367 MECQQKLIKELEGQRE 1382
Cdd:COG4372   344 QLLLVGLLDNDVLELL 359
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1037-1458 1.05e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 1.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1037 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNqeekskwegkqnslESELMEL 1116
Cdd:PRK02224  324 EELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDR--------------REEIEEL 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1117 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAavvearaqasaagileeDLRTARSALklkneevese 1196
Cdd:PRK02224  390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEA-----------------TLRTARERV---------- 442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1197 rERAQALQEQGELKVAqGKALQEnlALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSlDLKKRNQEVDLQQEQ 1276
Cdd:PRK02224  443 -EEAEALLEAGKCPEC-GQPVEG--SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEER 517

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1277 IQELEKcrsVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLvtlecl 1356
Cdd:PRK02224  518 REDLEE---LIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI------ 588

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1357 aleleENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLEShstvlarELQE-RDQEVKSQRE 1435
Cdd:PRK02224  589 -----ESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEA-------EFDEaRIEEAREDKE 656

                         410       420
                  ....*....|....*....|...
gi 768015747 1436 QIEELQRQKEHLTQDLERRDQEL 1458
Cdd:PRK02224  657 RAEEYLEQVEEKLDELREERDDL 679
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1060-1654 1.09e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1060 LRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG 1139
Cdd:TIGR04523  122 LEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLEL 201

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1140 ERELLQAAKEN---LTAQVEHLQAAVVEaraqasaagiLEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKA 1216
Cdd:TIGR04523  202 LLSNLKKKIQKnksLESQISELKKQNNQ----------LKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSE 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1217 LQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKaalellsldLKKRNQEVDLQQEQIQELEKcrsvlehlpmAVQE 1296
Cdd:TIGR04523  272 KQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDW---------NKELKSELKNQEKKLEEIQN----------QISQ 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1297 REQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEEnhhKMECQQKLIKE 1376
Cdd:TIGR04523  333 NNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES---KIQNQEKLNQQ 409

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1377 LEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ 1456
Cdd:TIGR04523  410 KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1457 ELMLQKERIQVLedqrTRQTKILEEDLEQIKlslRERGRELTTQRQLMQERAEegkgpskaqrgslehMKLILRDKEKEV 1536
Cdd:TIGR04523  490 ELKSKEKELKKL----NEEKKELEEKVKDLT---KKISSLKEKIEKLESEKKE---------------KESKISDLEDEL 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1537 ECQQEHIHelqelKDQLEQQLQGLHRKVGEtsllLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQE 1616
Cdd:TIGR04523  548 NKDDFELK-----KENLEKEIDEKNKEIEE----LKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 768015747  1617 LEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKE 1654
Cdd:TIGR04523  619 LEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 368-900 1.09e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   368 LARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAE 447
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   448 AEKRREalweKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsrhqqeaATTQLEQLHQEAKRQEEVLARAVQ 527
Cdd:TIGR04523  206 LKKKIQ----KNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN-------TQTQLNQLKDEQNKIKKQLSEKQK 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   528 EKEALVREKAALEVRLQAVERDRQDLAEQLQglssaKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQgevr 607
Cdd:TIGR04523  275 ELEQNNKKIKELEKQLNQLKSEISDLNNQKE-----QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS---- 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   608 clklELDTERSQAEQERDAAARQLAQAEQEGKTaLEQQKAAHEKEVNQLREKwekerswhQQELAKALESLEREKMELEM 687
Cdd:TIGR04523  346 ----QLKKELTNSESENSEKQRELEEKQNEIEK-LKKENQSYKQEIKNLESQ--------INDLESKIQNQEKLNQQKDE 412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   688 RLKEQQTEMEAIQaqREEERTQAESALCQMQLETEKERVSLLETLLqtqKELADASQQLERLRQDMKVQKLKEQETTGIL 767
Cdd:TIGR04523  413 QIKKLQQEKELLE--KEIERLKETIIKNNSEIKDLTNQDSVKELII---KNLDNTRESLETQLKVLSRSINKIKQNLEQK 487

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   768 QTQLQEAQRELKEAARQHRD---DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDD---------SQRLVEQEVQEKL 835
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKEleeKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddfelKKENLEKEIDEKN 567

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747   836 RETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQ 900
Cdd:TIGR04523  568 KEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSI 632
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
251-794 1.13e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  251 DLQGEVDSLSKERELLQKAREElRQQLEVLEQEAWRLRRVNVELQ-LQGDSAQGQKEEQQEELHLAVRERERLQEMLMGL 329
Cdd:COG4913   229 ALVEHFDDLERAHEALEDAREQ-IELLEPIRELAERYAAARERLAeLEYLRAALRLWFAQRRLELLEAELEELRAELARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  330 EAKQSESLSELITLREALEsshlegELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAavkLSALNEALALD 409
Cdd:COG4913   308 EAELERLEARLDALREELD------ELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEAL---LAALGLPLPAS 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  410 KVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQL----QKAEEAGAELQADLRDIQE 485
Cdd:COG4913   379 AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEA 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  486 E----KEEIQKKLSESR--------------------HQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEV 541
Cdd:COG4913   459 ElpfvGELIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAG 538

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  542 RLQAVERDRQDLAEQLQGLSSAKELLESslfEAQQQNSVIEVTK-GQL-------EVQIQTVTQAKEVIQGEVRCLKLEL 613
Cdd:COG4913   539 KLDFKPHPFRAWLEAELGRRFDYVCVDS---PEELRRHPRAITRaGQVkgngtrhEKDDRRRIRSRYVLGFDNRAKLAAL 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  614 DTERSQAEQERDAAARQLAQAEQEGKTALEQQKA---------------AHEKEVNQLREKWEKERSWHQ--QELAKALE 676
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALQERREAlqrlaeyswdeidvaSAEREIAELEAELERLDASSDdlAALEEQLE 695

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  677 SLEREKMELEMRLKEQQTEMEAIQAQR---EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDM 753
Cdd:COG4913   696 ELEAELEELEEELDELKGEIGRLEKELeqaEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERI 775

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 768015747  754 KVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQE 794
Cdd:COG4913   776 DALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPE 816
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 216-918 1.34e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.74  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   216 LLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQ 295
Cdd:pfam02463  304 KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   296 LQGDSAQGQKEEQQEELHLAVRE-------RERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAAL 368
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEaqlllelARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   369 ARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEA 448
Cdd:pfam02463  464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   449 EKRRE--ALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAV 526
Cdd:pfam02463  544 AISTAviVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   527 QEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEV 606
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   607 RCLKLELDTERSQAEQERDAAARQ---LAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKM 683
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVqeaQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKT 783

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   684 ELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQET 763
Cdd:pfam02463  784 EKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   764 TGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEvQEKLRETQEYNR 843
Cdd:pfam02463  864 TKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL-LKYEEEPEELLL 942

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747   844 IQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQ 918
Cdd:pfam02463  943 EEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1194-2024 1.36e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1194 ESERERAQALQEQGELKvaqgkalqENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQ 1273
Cdd:TIGR02169  167 EFDRKKEKALEELEEVE--------ENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1274 QEQIQ-ELEKCRSVLEHLPMAVQEREQKLTVQREQIREL----EKDRETQRNVLEHQLLELEKKdqmIESQRGQVQDLKK 1348
Cdd:TIGR02169  239 KEAIErQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkiKDLGEEEQLRVKEKIGELEAE---IASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1349 QLVTLECLALELEENHHKMECQqklIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQ 1428
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAE---IEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1429 EVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRqtkiLEEDLEQIKLSLRERGRELTTQRQLMQERA 1508
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE----LEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1509 EEgkgpskaqrgslehmkliLRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGE---TSLLLSQREQEIVVLQQQL 1585
Cdd:TIGR02169  469 QE------------------LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGgraVEEVLKASIQGVHGTVAQL 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1586 QEAREQGELK-EQSLQSQLD--------EAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAhMTLKE-- 1654
Cdd:TIGR02169  531 GSVGERYATAiEVAAGNRLNnvvveddaVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFA-VDLVEfd 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1655 -----------RHGELQDHKEQARR---------LEEEL----------AVEGRRVQALEEVLGDLRAESREQEKALLAL 1704
Cdd:TIGR02169  610 pkyepafkyvfGDTLVVEDIEAARRlmgkyrmvtLEGELfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRE 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1705 QQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLE 1784
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1785 QAELSRSLEASTATLQASLDacQAHSRQLEEALRIQEGEIQDQDLRYQEdvqqlqqalaqRDEELRHQQEREQLLEKSLA 1864
Cdd:TIGR02169  770 LEEDLHKLEEALNDLEARLS--HSRIPEIQAELSKLEEEVSRIEARLRE-----------IEQKLNRLTLEKEYLEKEIQ 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1865 QRVQENMIQEKQNLGQEREEEEIRGlhqSVRELQLTLAQKEQEILELRE-----TQQRNNLEAlPHSHKTSPMEEQSLKL 1939
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNG---KKEELEEELEELEAALRDLESrlgdlKKERDELEA-QLRELERKIEELEAQI 912

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1940 DSLEPRLQRELERLQAALRQTEAREIEWRE---------KAQDLALSLAQTKASVSSLQEVAMflqASVLERDSEQQRLq 2010
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelSLEDVQAELQRVEEEIRALEPVNM---LAIQEYEEVLKRL- 988

                          890
                   ....*....|....
gi 768015747  2011 DELELTRRALEKER 2024
Cdd:TIGR02169  989 DELKEKRAKLEEER 1002
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1043-1703 1.37e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1043 LHKLHQDLWKTQQTRDVLR------DQVQKLEERLTDTEAEKSQVhtELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL 1116
Cdd:COG4913   237 LERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEAELERL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1117 HETMASLQSRLRRAELQRMEAQGERellqaaKENLTAQVEHLQAavvEARAQASAAGILEEDLRTARSALKLKNEEVESE 1196
Cdd:COG4913   315 EARLDALREELDELEAQIRGNGGDR------LEQLEREIERLER---ELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1197 RERAQALQEQGElkvAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQR----EMQKAALELLSLDLKKRNQEVDL 1272
Cdd:COG4913   386 RAEAAALLEALE---EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAELPF 462

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1273 QQEQIQELEKCRS-------VL-----------EHLPMA---VQEREQKLTVQREQIRELEKDRETQRnVLEHQLLElek 1331
Cdd:COG4913   463 VGELIEVRPEEERwrgaierVLggfaltllvppEHYAAAlrwVNRLHLRGRLVYERVRTGLPDPERPR-LDPDSLAG--- 538

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1332 kdqMIESQRGQVQDLKKQLVtleclalELEENHHKMECQQKLikelegqRETQRvALThltldleersqeLQAQSSQIHD 1411
Cdd:COG4913   539 ---KLDFKPHPFRAWLEAEL-------GRRFDYVCVDSPEEL-------RRHPR-AIT------------RAGQVKGNGT 588

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1412 LESHSTvlARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLR 1491
Cdd:COG4913   589 RHEKDD--RRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASA 666

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1492 ERGRelttqRQLMQERAEegkgpskaqrgslehmkliLRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETslll 1571
Cdd:COG4913   667 EREI-----AELEAELER-------------------LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRL---- 718

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1572 sqrEQEIVVLQQQLQEAREQ----GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1647
Cdd:COG4913   719 ---EKELEQAEEELDELQDRleaaEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747 1648 AHMTLKERHGELQDHKEQARRLEEELA-VEGRRVQALEEVLGDLRAESREQEKALLA 1703
Cdd:COG4913   796 FNREWPAETADLDADLESLPEYLALLDrLEEDGLPEYEERFKELLNENSIEFVADLL 852
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
414-843 1.72e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  414 NQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREA--LWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQ 491
Cdd:COG4717    87 EEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlpLYQELEALEAELAELPERLEELEERLEELRELEEELE 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  492 KKLSESRHQQEAATTQLEQL----HQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELL 567
Cdd:COG4717   167 ELEAELAELQEELEELLEQLslatEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLK 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  568 E-SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQK 646
Cdd:COG4717   247 EaRLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLA 326

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  647 AAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAesalcqmqLETEKERV 726
Cdd:COG4717   327 ALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAA--------LEQAEEYQ 398

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  727 SLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTgiLQTQLQEAQRELKEAARQHRDDLAALQE-ESSSLLQDKMD 805
Cdd:COG4717   399 ELKEELEELEEQLEELLGELEELLEALDEEELEEELEE--LEEELEELEEELEELREELAELEAELEQlEEDGELAELLQ 476

                         410       420       430
                  ....*....|....*....|....*....|....*...
gi 768015747  806 LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNR 843
Cdd:COG4717   477 ELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 638-1424 2.28e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.73  E-value: 2.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   638 GKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLerekMELEMRLKEQQTEMEAIQAQREEERTQAESALCQM 717
Cdd:pfam15921   72 GKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSV----IDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQL 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   718 QletekERVSLLETLLQTQKE-LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEES 796
Cdd:pfam15921  148 Q-----NTVHELEAAKCLKEDmLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAI 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   797 SSLLQdkmDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRetqeynriqkelerekasltLSLMEKEQRllvLQEADSIR 876
Cdd:pfam15921  223 SKILR---ELDTEISYLKGRIFPVEDQLEALKSESQNKIE--------------------LLLQQHQDR---IEQLISEH 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   877 QQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQeaqlLEELEAshiTEQQLRASLwaQEAKaAQLQLRLRS 956
Cdd:pfam15921  277 EVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ----LSDLES---TVSQLRSEL--REAK-RMYEDKIEE 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   957 TESQLEALAAEQQPGNQAQAQAQLAS--LYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKR------- 1027
Cdd:pfam15921  347 LEKQLVLANSELTEARTERDQFSQESgnLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRelddrnm 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1028 -----GPLLTALSAEAVAS-------------ALHKLHQDLWKTQQTRDVLRDQVQKLEER---LTDTEAEKSQVHTELQ 1086
Cdd:pfam15921  427 evqrlEALLKAMKSECQGQmerqmaaiqgkneSLEKVSSLTAQLESTKEMLRKVVEELTAKkmtLESSERTVSDLTASLQ 506

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1087 DLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEAR 1166
Cdd:pfam15921  507 EKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAG 586

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1167 AQASAAGILEEDLRTARSALK----LKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREE---EVETLR 1239
Cdd:pfam15921  587 AMQVEKAQLEKEINDRRLELQefkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQllnEVKTSR 666

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1240 GQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQ-ELEKCRSVLE-------HLPMAVQEREQKLTVQREQIREL 1311
Cdd:pfam15921  667 NELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQTRNTLKsmegsdgHAMKVAMGMQKQITAKRGQIDAL 746

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1312 ekdrETQRNVLEHQLLELEKKDQMIESQRGQvqdLKKQLVTLECLALELEENHHKMECQQKLIKELEGQREtqrVALTHL 1391
Cdd:pfam15921  747 ----QSKIQFLEEAMTNANKEKHFLKEEKNK---LSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME---VALDKA 816

                          810       820       830
                   ....*....|....*....|....*....|...
gi 768015747  1392 TLDLEERSQELQAQSSQIHDLESHSTVLARELQ 1424
Cdd:pfam15921  817 SLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 399-629 2.62e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  399 LSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQA 478
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  479 DLRDIQEEKEEIQKKLSE--------SRHQQEAATTQLEQLHQEAKRQE---EVLARAVQEKEALVREKAALEVRLQAVE 547
Cdd:COG4942    91 EIAELRAELEAQKEELAEllralyrlGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  548 RDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAA 627
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250


                  ..
gi 768015747  628 AR 629
Cdd:COG4942   251 LK 252
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 734-987 2.71e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  734 QTQKELADASQQLERLRQDMKVQKLKEQEttgiLQTQLQEAQRELKEAARQhrddLAALQEESSSLLQDKMDLQKQVEDL 813
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKA----LLKQLAALERRIAALARR----IRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  814 KSQLVAQddsqrlvEQEVQEKLRETQEYNRIQKELEREKASltlSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGE 893
Cdd:COG4942    96 RAELEAQ-------KEELAELLRALYRLGRQPPLALLLSPE---DFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  894 QKELSAQMELLRQEVKEKEAdflaQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQ 973
Cdd:COG4942   166 RAELEAERAELEALLAELEE----ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241

                         250
                  ....*....|....
gi 768015747  974 AQAQAQLASLYSAL 987
Cdd:COG4942   242 RTPAAGFAALKGKL 255
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1633-2049 2.94e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.57  E-value: 2.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1633 RVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEElavegrrVQALEEVLGDLRAESREQekallalqqqcaeqa 1712
Cdd:COG3096   351 RYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEE-------VDSLKSQLADYQQALDVQ--------------- 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1713 qehevETRALQdsWLQAQAVLkERDQELEALRAESqssrhqeeaararaealQEALGKAHAALQGKEQhlleqaelsrSL 1792
Cdd:COG3096   409 -----QTRAIQ--YQQAVQAL-EKARALCGLPDLT-----------------PENAEDYLAAFRAKEQ----------QA 453

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1793 EASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDlryQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMI 1872
Cdd:COG3096   454 TEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVE---RSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQ 530

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1873 QEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELrETQQRNNLEALphshktspmeeqslkldslePRLQRELER 1952
Cdd:COG3096   531 QQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEEL-EEQAAEAVEQR--------------------SELRQQLEQ 589

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1953 LQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQaSVLERDSEQQRLQDELELTRRALEK--ERLHSPGA 2030
Cdd:COG3096   590 LRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQ-QLLEREREATVERDELAARKQALESqiERLSQPGG 668

                         410       420
                  ....*....|....*....|.
gi 768015747 2031 TSTAELGSRGEQ--GVQLGEV 2049
Cdd:COG3096   669 AEDPRLLALAERlgGVLLSEI 689
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 167-912 3.64e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.27  E-value: 3.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   167 LELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQdlrQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQ----KLTGER 242
Cdd:TIGR00606  377 LELDGFERGPFSERQIKNFHTLVIERQEDEAKTAA---QLCADLQSKERLKQEQADEIRDEKKGLGRTIElkkeILEKKQ 453

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   243 DTLAGQTVDLQGEVDSLSKERELLQKAREELRQqLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERL 322
Cdd:TIGR00606  454 EELKFVIKELQQLEGSSDRILELDQELRKAERE-LSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTT 532

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   323 QEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTaalaraEQSIAELSSSENTLKTEVADLRAAAVKLSAL 402
Cdd:TIGR00606  533 TRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQL------EDWLHSKSKEINQTRDRLAKLNKELASLEQN 606

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   403 NEALALDKVGLNQQLLQLEEENQSVCSrMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRD 482
Cdd:TIGR00606  607 KNHINNELESKEEQLSSYEDKLFDVCG-SQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR 685

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   483 IQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEevlaravQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSS 562
Cdd:TIGR00606  686 VFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKE-------KRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR 758

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   563 AKELLESSLFEAQQQNSVIeVTKGQLEVQIQTVTQAKEVIQGEVRclklelDTERSQAEQERDAAARQLAQAEQEGKTAL 642
Cdd:TIGR00606  759 DIQRLKNDIEEQETLLGTI-MPEEESAKVCLTDVTIMERFQMELK------DVERKIAQQAAKLQGSDLDRTVQQVNQEK 831

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   643 EQQKAAHEKEVNQLRE--KWEKERSWHQQELAKALESLEREKMELEMRLKEQQtemeAIQAQREEERTQAESalCQMQLE 720
Cdd:TIGR00606  832 QEKQHELDTVVSKIELnrKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQ----QFEEQLVELSTEVQS--LIREIK 905

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   721 TEKERVSLLETLL---QTQKELADASQQLERLRQDMKVQKLKEQ--ETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 795
Cdd:TIGR00606  906 DAKEQDSPLETFLekdQQEKEELISSKETSNKKAQDKVNDIKEKvkNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   796 ssslLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIqKELEREKASLTLSLmeKEQRLLVLQEADSI 875
Cdd:TIGR00606  986 ----LEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENEL-KEVEEELKQHLKEM--GQMQVLQMKQEHQK 1058

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 768015747   876 RQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKE 912
Cdd:TIGR00606 1059 LEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQ 1095
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1159-1475 4.45e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 4.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1159 QAAVVEARAQASAAGILEEDLRTARSALKLKNEE----VESERERAQALQEQGELKVAQGK-ALQENLALLTQTLAEREE 1233
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERrrklEEAEKARQAEMDRQAAIYAEQERmAMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1234 EVETLRGQ--IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREL 1311
Cdd:pfam17380  361 ELERIRQEeiAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1312 EKDRETQrnvLEHQLLELEKKDQMIESQRGQVQDLKKQlvtlecLALELEENHHKMECQQKLIKELEGQRETQRVALTHl 1391
Cdd:pfam17380  441 EEERARE---MERVRLEEQERQQQVERLRQQEEERKRK------KLELEKEKRDRKRAEEQRRKILEKELEERKQAMIE- 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1392 tldlEERSQELQAQssqihDLESHSTVLARELQERDQEVKSQREQ-IEELQRQKEHLTQDLERRDQELMLQKER---IQV 1467
Cdd:pfam17380  511 ----EERKRKLLEK-----EMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSRLEAMERERemmRQI 581


                   ....*...
gi 768015747  1468 LEDQRTRQ 1475
Cdd:pfam17380  582 VESEKARA 589
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 673-1537 4.57e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.89  E-value: 4.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   673 KALESLEREKMELEMRLKEQQTEMEAIQAQRE---EERTQAESALCQMQLETE--KERVSLLETLLQTQKELADASQQLE 747
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKQYKEkacEIRDQITSKEAQLESSREivKSYENELDPLKNRLKEIEHNLSKIM 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   748 RLRQDMKVQKLKEQETTGiLQTQLQEAQRELKEAARQHRDDLAAL-QEESSSLLQDKMDLQKQVEDL--KSQLVAQDDSQ 824
Cdd:TIGR00606  266 KLDNEIKALKSRKKQMEK-DNSELELKMEKVFQGTDEQLNDLYHNhQRTVREKERELVDCQRELEKLnkERRLLNQEKTE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   825 RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADS-----IRQQELSALRQDMQEAQGEQKELSA 899
Cdd:TIGR00606  345 LLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNfhtlvIERQEDEAKTAAQLCADLQSKERLK 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   900 QMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRA-SLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQA 978
Cdd:TIGR00606  425 QEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELqQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVK 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   979 QLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASAL---HKLHQDLWKTQQ 1055
Cdd:TIGR00606  505 SLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFpnkKQLEDWLHSKSK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1056 TRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQnSLESELMELHETMAslQSRLRRAELQRM 1135
Cdd:TIGR00606  585 EINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQ-DEESDLERLKEEIE--KSSKQRAMLAGA 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1136 EAQGERELLQAAKEN-----LTAQVEHLQAAVVEARAQASAAGILEED-LRTARSALKLKNEEVESERERAQALQEQGEL 1209
Cdd:TIGR00606  662 TAVYSQFITQLTDENqsccpVCQRVFQTEAELQEFISDLQSKLRLAPDkLKSTESELKKKEKRRDEMLGLAPGRQSIIDL 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1210 KVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAAL------ELLSLDLKKRNQEVDLQQEQIQELEKC 1283
Cdd:TIGR00606  742 KEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLtdvtimERFQMELKDVERKIAQQAAKLQGSDLD 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1284 RSV--LEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELE 1361
Cdd:TIGR00606  822 RTVqqVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLI 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1362 ENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQ-ELQAQSSQIHDLESHSTVLARELQERDQEVKSQRE----- 1435
Cdd:TIGR00606  902 REIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQdKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKEtelnt 981

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1436 ---QIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRqtKILEEDLEQIKLSLRERGRELtTQRQLMQERAEEGK 1512
Cdd:TIGR00606  982 vnaQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTL--RKRENELKEVEEELKQHLKEM-GQMQVLQMKQEHQK 1058

                          890       900
                   ....*....|....*....|....*
gi 768015747  1513 GPSKAQRGSLEHMKLILRDKEKEVE 1537
Cdd:TIGR00606 1059 LEENIDLIKRNHVLALGRQKGYEKE 1083
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1035-1671 5.18e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.81  E-value: 5.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1035 SAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTdTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELM 1114
Cdd:TIGR00618  220 RKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLK-KQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAH 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1115 ELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVE 1194
Cdd:TIGR00618  299 IKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLT 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1195 SERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ 1274
Cdd:TIGR00618  379 QHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1275 EQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLE 1354
Cdd:TIGR00618  459 IHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1355 CLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTldleersQELQAQSSQIHDLESHSTVLARELQERDQEVKSQR 1434
Cdd:TIGR00618  539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILT-------QCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1435 EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGP 1514
Cdd:TIGR00618  612 CEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQ 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1515 SKAQRGSLEHMKLILRDKEKEVECQQEHIHELQE----LKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQE--- 1587
Cdd:TIGR00618  692 LTYWKEMLAQCQTLLRELETHIEEYDREFNEIENasssLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEevt 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1588 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD-ALQGALEQAHMTLKERHGELQDHKEQA 1666
Cdd:TIGR00618  772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCeTLVQEEEQFLSRLEEKSATLGEITHQL 851


                   ....*
gi 768015747  1667 RRLEE 1671
Cdd:TIGR00618  852 LKYEE 856
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1064-1349 5.62e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 48.48  E-value: 5.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1064 VQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELhetmasLQSRLRRAELQRMEAQGERel 1143
Cdd:pfam05667  228 SQGLASRLTPEEYRKRKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAEL------LSSFSGSSTTDTGLTKGSR-- 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1144 lQAAKENLTAQVEHLQAAVVEARAQASaagilEEDLRTARSalklknEEVESERERAQALQEQGElkvaqgkALQENLAL 1223
Cdd:pfam05667  300 -FTHTEKLQFTNEAPAATSSPPTKVET-----EEELQQQRE------EELEELQEQLEDLESSIQ-------ELEKEIKK 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1224 LTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLD---LKKRNQEVDLQQEQIQEL----EKCRS--VLEHLPMAV 1294
Cdd:pfam05667  361 LESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPDAeenIAKLQALVDASAQRLVELagqwEKHRVplIEEYRALKE 440

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  1295 QEREQKLTVQReQIRELEKDRETQRNVLEhqllELEKKDQMIESQRGQVQDLKKQ 1349
Cdd:pfam05667  441 AKSNKEDESQR-KLEEIKELREKIKEVAE----EAKQKEELYKQLVAEYERLPKD 490
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1038-1750 6.69e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 6.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1038 AVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELH 1117
Cdd:TIGR02169  291 RVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1118 ETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARSALKLKNEEVESER 1197
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKA 447

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1198 ERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREM-------QKAALELLSLDLKKRnqeV 1270
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAseervrgGRAVEEVLKASIQGV---H 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1271 DLQQEQIQELEKCRSVLEhlpMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1350
Cdd:TIGR02169  525 GTVAQLGSVGERYATAIE---VAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGF 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1351 VTLECLALELEENHHKMECQQKLIKE--LEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQErdq 1428
Cdd:TIGR02169  602 AVDLVEFDPKYEPAFKYVFGDTLVVEdiEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQR--- 678

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1429 evksQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEdqrtRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERA 1508
Cdd:TIGR02169  679 ----LRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS----RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1509 EEgkgpskaqrgsLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLqglhrkvgetslllsqREQEIVVLQQQLQEA 1588
Cdd:TIGR02169  751 QE-----------IENVKSELKELEARIEELEEDLHKLEEALNDLEARL----------------SHSRIPEIQAELSKL 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1589 REQgelkEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKadalqgaleqahmtLKERHGELQDHKEQARR 1668
Cdd:TIGR02169  804 EEE----VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ--------------IKSIEKEIENLNGKKEE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1669 LEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQehEVETRALQDSWLQAQA-VLKERDQELEALRAES 1747
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA--QIEKKRKRLSELKAKLeALEEELSEIEDPKGED 943


                   ...
gi 768015747  1748 QSS 1750
Cdd:TIGR02169  944 EEI 946
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 206-817 7.39e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 7.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   206 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLqklTGERDTLAGQTVDLQGEVDSLSKERELLQKAR-EELRQQLEVLEQEA 284
Cdd:pfam12128  277 RQEERQETSAELNQLLRTLDDQWKEKRDEL---NGELSAADAAVAKDRSELEALEDQHGAFLDADiETAAADQEQLPSWQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   285 WRLRRVNVELQLQGDSAQGQKEEQQEELHLAVrerERLQEMLMGLEAKQsESLSELITLREALESSHLEGelLRQEQTEv 364
Cdd:pfam12128  354 SELENLEERLKALTGKHQDVTAKYNRRRSKIK---EQNNRDIAGIKDKL-AKIREARDRQLAVAEDDLQA--LESELRE- 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   365 taalaRAEQSIAELSSSENTLKTEVADLRaaavklsalneaLALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNA---- 440
Cdd:pfam12128  427 -----QLEAGKLEFNEEEYRLKSRLGELK------------LRLNQATATPELLLQLENFDERIERAREEQEAANAever 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   441 LQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEE 520
Cdd:pfam12128  490 LQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEV 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   521 VLARAVQEKEALvrekaALEVRLQAVER-DRQDLAEQLQG-LSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQA 598
Cdd:pfam12128  570 WDGSVGGELNLY-----GVKLDLKRIDVpEWAASEEELRErLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   599 KeviqgevrclkleldtersQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESL 678
Cdd:pfam12128  645 R-------------------TALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQ 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   679 EREKMELEMRLKEQQTEME--------AIQAQREEERTQAESALCQMQLETEKERVSL---LETLLQTQKELADASQQLE 747
Cdd:pfam12128  706 KEQKREARTEKQAYWQVVEgaldaqlaLLKAAIAARRSGAKAELKALETWYKRDLASLgvdPDVIAKLKREIRTLERKIE 785

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747   748 RLRQD-MKVQKLKE--QETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQL 817
Cdd:pfam12128  786 RIAVRrQEVLRYFDwyQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRL 858
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1112-1325 1.03e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1112 ELMELHETMASLQSRLRRaeLQRMEAQGERelLQAAKENLTAQVEHLQAAVVEARAQASAAgiLEEDLRTARSAL-KLKN 1190
Cdd:COG4913   236 DLERAHEALEDAREQIEL--LEPIRELAER--YAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELaRLEA 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1191 EEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEV 1270
Cdd:COG4913   310 ELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 768015747 1271 DLQQEQIQELEKcrsvlehlpmAVQEREQKLTVQREQIRELEKDRETQRNVLEHQ 1325
Cdd:COG4913   390 AALLEALEEELE----------ALEEALAEAEAALRDLRRELRELEAEIASLERR 434
mukB PRK04863
chromosome partition protein MukB;
351-801 1.10e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  351 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSR 430
Cdd:PRK04863  257 DLFKHLITESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDH 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  431 MEAAEQARNAlqvdlAEAEKR-REALWEKNTHLEAQLQKAEEAG---AELQADLRDIQEEKEEIQKKLSESRHQQEAATT 506
Cdd:PRK04863  337 LNLVQTALRQ-----QEKIERyQADLEELEERLEEQNEVVEEADeqqEENEARAEAAEEEVDELKSQLADYQQALDVQQT 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  507 QLEQLHQEAKRQEEvlARAVQEKEALVREKAalEVRLQAVERDRQDLAEQlqglssakellessLFEAQQQNSVIEVTKG 586
Cdd:PRK04863  412 RAIQYQQAVQALER--AKQLCGLPDLTADNA--EDWLEEFQAKEQEATEE--------------LLSLEQKLSVAQAAHS 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  587 QLEVQIQTVTQA-----KEVIQGEVRCLKLELDTERSQAEQErDAAARQLAQAEQEgktaLEQQKAAhekevNQLREKWE 661
Cdd:PRK04863  474 QFEQAYQLVRKIagevsRSEAWDVARELLRRLREQRHLAEQL-QQLRMRLSELEQR----LRQQQRA-----ERLLAEFC 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  662 KErswHQQELAKAlESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAEsalcqmQLETEKERVSLLETLLQTqkelad 741
Cdd:PRK04863  544 KR---LGKNLDDE-DELEQLQEELEARLESLSESVSEARERRMALRQQLE------QLQARIQRLAARAPAWLA------ 607

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  742 ASQQLERLRQDMKVQKLKEQETTGILQtQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 801
Cdd:PRK04863  608 AQDALARLREQSGEEFEDSQDVTEYMQ-QLLERERELTVERDELAARKQALDEEIERLSQ 666
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1105-1339 1.11e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1105 KQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAagiLEEDLRTARS 1184
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE---LEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1185 ALKLKNEEVESERERAQALQEQGELKV----AQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLS 1260
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747 1261 LDLKKrnqevdlQQEQIQELEKCRSVLEHLpmaVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQ 1339
Cdd:COG4942   178 ALLAE-------LEEERAALEALKAERQKL---LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
PTZ00121 PTZ00121
MAEBL; Provisional
 1784-2214 1.37e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1784 EQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALaqRDEELRHQQEREQLlekSL 1863
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR--KAEEARKAEDAKRV---EI 1156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1864 AQRVQE-NMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEE----QSLK 1938
Cdd:PTZ00121 1157 ARKAEDaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAvkkaEEAK 1236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1939 LDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRR 2018
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKK 1316

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 2019 ALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTL 2098
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 2099 EQVERERRKLKREAMRAAQA-GSLEISKATASSPTQQDGRGQKNSDAKCVAELQKEV----VLLQAQLTLERKQKQDYIT 2173
Cdd:PTZ00121 1397 KKKAEEDKKKADELKKAAAAkKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAeeakKAEEAKKKAEEAKKADEAK 1476

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 768015747 2174 RSAQTSRElagLHHSLSHSLLAVAQAPEATVLEAETRRLDE 2214
Cdd:PTZ00121 1477 KKAEEAKK---ADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 615-938 1.61e-04

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 46.45  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   615 TERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQT 694
Cdd:pfam13868   22 KERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQERE 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   695 EMEAIQAQREEERtqaesalcqmqletEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEA 774
Cdd:pfam13868  102 QMDEIVERIQEED--------------QAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAER 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   775 QRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKAS 854
Cdd:pfam13868  168 EEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIEL 247

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   855 ltLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQ 934
Cdd:pfam13868  248 --KERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEA 325


                   ....
gi 768015747   935 QLRA 938
Cdd:pfam13868  326 ERRE 329
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
363-913 1.68e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 1.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  363 EVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALAldkvGLNQQLLQLEEENQSVCSRMEAAEQARNALQ 442
Cdd:PRK03918  197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE----ELEKELESLEGSKRKLEEKIRELEERIEELK 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  443 VDLAEAEKRREALWE------KNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsRHQQEAATTQLEQLHQEAK 516
Cdd:PRK03918  273 KEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKE-LEEKEERLEELKKKLKELE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  517 RQEEVLARAVQEKEALVREKAALE-VRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTV 595
Cdd:PRK03918  352 KRLEELEERHELYEEAKAKKEELErLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEEL 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  596 TQAKeviqGEVRCLKLELDTERSqaeqerdaaARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKAL 675
Cdd:PRK03918  432 KKAK----GKCPVCGRELTEEHR---------KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  676 ESLEREKMELEMRLKEQQTEmEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMkv 755
Cdd:PRK03918  499 KELAEQLKELEEKLKKYNLE-ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL-- 575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  756 qkLKEQETTGIlqTQLQEAQRELKEAARQHRDDLAALQEESssllqDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKL 835
Cdd:PRK03918  576 --LKELEELGF--ESVEELEERLKELEPFYNEYLELKDAEK-----ELEREEKELKKLEEELDKAFEELAETEKRLEELR 646

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  836 RETQEYNRIQKELEREKAS-LTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEA 913
Cdd:PRK03918  647 KELEELEKKYSEEEYEELReEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 446-822 1.90e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 46.54  E-value: 1.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  446 AEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLrdiqeekEEIQKKLSESRHQQEAA-TTQLEQLHQEAKRQEEVLaR 524
Cdd:NF033838   37 AEEVRGGNNPTVTSSGNESQKEHAKEVESHLEKIL-------SEIQKSLDKRKHTQNVAlNKKLSDIKTEYLYELNVL-K 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  525 AVQEKEALVREKAALEVrlqAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQnsvievtKGQLEVQIQTVTQAK---EV 601
Cdd:NF033838  109 EKSEAELTSKTKKELDA---AFEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQ-------KEEDRRNYPTNTYKTlelEI 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  602 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTAleqqKAAHEKEVNQLREKWEKE-RSWHQQELAKALESL-- 678
Cdd:NF033838  179 AESDVEVKKAELELVKEEAKEPRDEEKIKQAKAKVESKKA----EATRLEKIKTDREKAEEEaKRRADAKLKEAVEKNva 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  679 EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQmqlETekervsLLETLLQTQKELADASQQLERLRQDMKVQKL 758
Cdd:NF033838  255 TSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDSSVGE---ET------LPSPSLKPEKKVAEAEKKVEEAKKKAKDQKE 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  759 KEQE-----TTGILQTQLQEAQRELKEA-----------------ARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQ 816
Cdd:NF033838  326 EDRRnyptnTYKTLELEIAESDVKVKEAelelvkeeakeprneekIKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRK 405


                  ....*.
gi 768015747  817 LVAQDD 822
Cdd:NF033838  406 AAEEDK 411
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 722-1349 2.02e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.89  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   722 EKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 801
Cdd:TIGR00618  225 EKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQ 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   802 DKMDLQKQVEDLKSQL------------VAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVL 869
Cdd:TIGR00618  305 IEQQAQRIHTELQSKMrsrakllmkraaHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   870 QEADSIRQQELSALRQDMQEAQGEQkelsAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQ 949
Cdd:TIGR00618  385 QQQKTTLTQKLQSLCKELDILQREQ----ATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   950 LQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQAL-----GSVCESRPELSGGGDSAPSVWGLEPDQNGARSL 1024
Cdd:TIGR00618  461 LQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEpcplcGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1025 FKrgplltalSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEG 1104
Cdd:TIGR00618  541 ET--------SEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1105 KQNSLESEL-MELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTA--------QVEHLQAAVVEARAQASAAGIL 1175
Cdd:TIGR00618  613 EQHALLRKLqPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREhalsirvlPKELLASRQLALQKMQSEKEQL 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1176 EEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAA 1255
Cdd:TIGR00618  693 TYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTA 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1256 LELLSLDLKKRNQEVDLQQEQIQEL-EKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQ 1334
Cdd:TIGR00618  773 ALQTGAELSHLAAEIQFFNRLREEDtHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852

                          650
                   ....*....|....*
gi 768015747  1335 MIESQRGQVQDLKKQ 1349
Cdd:TIGR00618  853 KYEECSKQLAQLTQE 867
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 27-283 2.11e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 2.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747    27 SREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELiqlksqgdlekAELQDRVTELSALLTQSQKQNEDYEKMIKA 106
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL-----------RRIENRLDELSQELSDASRKIGEIEKEIEQ 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   107 LRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEegdnIAQGSGHENSLE--LDSSIFSQFD--YQDA 182
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED----LHKLEEALNDLEarLSHSRIPEIQaeLSKL 803

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   183 DKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE 262
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          250       260
                   ....*....|....*....|.
gi 768015747   263 RELLQKAREELRQQLEVLEQE 283
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERK 904
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 236-994 2.15e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.71  E-value: 2.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   236 QKLTGERDTLAGQTVDLQGEVDSLskeRELLQKAREELRQQLEVLEQEAWR---LRRVNVELQLQGDSAQGQKEEQQEEL 312
Cdd:pfam01576  211 RKLEGESTDLQEQIAELQAQIAEL---RAQLAKKEEELQAALARLEEETAQknnALKKIRELEAQISELQEDLESERAAR 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   313 HLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLE-GELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVAD 391
Cdd:pfam01576  288 NKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEvTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQ 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   392 LRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQ---- 467
Cdd:pfam01576  368 AKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELEsvss 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   468 ---KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQ 544
Cdd:pfam01576  448 llnEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLS 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   545 AVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEvqiqtvtQAKEVIQGEVRCLKLELDTERsQAEQER 624
Cdd:pfam01576  528 DMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLE-------KTKNRLQQELDDLLVDLDHQR-QLVSNL 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   625 DAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSwhqqeLAKALESLEREKMELEMRLKEQQTEMEAIQAQRE 704
Cdd:pfam01576  600 EKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS-----LARALEEALEAKEELERTNKQLRAEMEDLVSSKD 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   705 E------ERTQAESALCQmQLETEKERVSLLETLLQTQKelaDASQQLERLRQDMKVQKLKEQETTgilQTQLQEAQREL 778
Cdd:pfam01576  675 DvgknvhELERSKRALEQ-QVEEMKTQLEELEDELQATE---DAKLRLEVNMQALKAQFERDLQAR---DEQGEEKRRQL 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   779 KEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLS 858
Cdd:pfam01576  748 VKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQ 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   859 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELS---AQMELLRQEVKEKEADFLAQEAQLLEELEashitEQQ 935
Cdd:pfam01576  828 SKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELAdeiASGASGKSALQDEKRRLEARIAQLEEELE-----EEQ 902

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747   936 LRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSV 994
Cdd:pfam01576  903 SNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTV 961
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1080-1921 2.16e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 2.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1080 QVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQ 1159
Cdd:pfam02463  189 IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1160 AAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLR 1239
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1240 GQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEhlpmavQEREQKLTVQREQIRELEKDRETQR 1319
Cdd:pfam02463  349 IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL------ELKSEEEKEAQLLLELARQLEDLLK 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1320 NVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRetQRVALTHLTLDLEERS 1399
Cdd:pfam02463  423 EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE--QLELLLSRQKLEERSQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1400 QELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLE---RRDQELMLQKERIQVLEDQRTRQT 1476
Cdd:pfam02463  501 KESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsatADEVEERQKLVRALTELPLGARKL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1477 KILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKE-----------VECQQEHIHE 1545
Cdd:pfam02463  581 RLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKEsakakesglrkGVSLEEGLAE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1546 LQELKDQLEQQLQGLHRKVgETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ 1625
Cdd:pfam02463  661 KSEVKASLSELTKELLEIQ-ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELK 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1626 QAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQ 1705
Cdd:pfam02463  740 LLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEE 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1706 QQCAEQAQEHEVETRALQdswLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQ 1785
Cdd:pfam02463  820 EQLLIEQEEKIKEEELEE---LALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEK 896

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1786 AELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQ 1865
Cdd:pfam02463  897 EEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVN 976

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 768015747  1866 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLE 1921
Cdd:pfam02463  977 LMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKG 1032
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 260-538 2.23e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  260 SKERELLQKAREELRQQLEVLEQEawrlrrvnvelqlqgdsaqgqkeeqqeelhlavrererlqemLMGLEAKQSESLSE 339
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKE------------------------------------------LAALKKEEKALLKQ 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  340 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALAldkvglnqqLLQ 419
Cdd:COG4942    57 LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLAL---------LLS 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  420 LEEENQSVcSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 499
Cdd:COG4942   128 PEDFLDAV-RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK 206

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 768015747  500 QQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAA 538
Cdd:COG4942   207 ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1576-1753 2.29e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1576 QEIVVLQQQLQEAREQ-GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKE 1654
Cdd:COG4913   255 EPIRELAERYAAARERlAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1655 RHGE-LQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVL 1733
Cdd:COG4913   335 NGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAL 414

                         170       180
                  ....*....|....*....|
gi 768015747 1734 KERDQELEALRAESQSSRHQ 1753
Cdd:COG4913   415 RDLRRELRELEAEIASLERR 434
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 462-603 2.44e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 46.36  E-value: 2.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  462 LEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSEsrhQQEAATTQLEQLHQEAKrqeEVLARAVQEKEALVREKAALEv 541
Cdd:PRK00409  525 LEELERELEQKAEEAEALLKEAEKLKEELEEKKEK---LQEEEDKLLEEAEKEAQ---QAIKEAKKEADEIIKELRQLQ- 597

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768015747  542 RLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVtkGQlEVQIQTVTQAKEVIQ 603
Cdd:PRK00409  598 KGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELKV--GD-EVKYLSLGQKGEVLS 656
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 419-922 3.62e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 3.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   419 QLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQ-------LQKAEEAGAELQADLRDIQEE----K 487
Cdd:TIGR04523   37 QLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQikdlndkLKKNKDKINKLNSDLSKINSEikndK 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   488 EEIQKK---LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSS-- 562
Cdd:TIGR04523  117 EQKNKLeveLNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNkl 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   563 -AKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLEL---DTERSQAEQERDAAARQLAQAEQEG 638
Cdd:TIGR04523  197 lKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIsntQTQLNQLKDEQNKIKKQLSEKQKEL 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   639 KTAlEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESlerekmelemRLKEQQTEMEAIQAQREEErTQAESALCQMQ 718
Cdd:TIGR04523  277 EQN-NKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKS----------ELKNQEKKLEEIQNQISQN-NKIISQLNEQI 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   719 LETEKERVSLLETLLQTQKELADASQQLERLR--QDMKVQKLKEQET-TGILQTQLQEAQRELKEaarqhrddlaaLQEE 795
Cdd:TIGR04523  345 SQLKKELTNSESENSEKQRELEEKQNEIEKLKkeNQSYKQEIKNLESqINDLESKIQNQEKLNQQ-----------KDEQ 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   796 SSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSI 875
Cdd:TIGR04523  414 IKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS 493

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 768015747   876 RQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQL 922
Cdd:TIGR04523  494 KEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKI 540
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
655-831 3.74e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 3.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  655 QLREKWEKERSWhqQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERvslLETLLQ 734
Cdd:COG4717    79 ELKEAEEKEEEY--AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPER---LEELEE 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  735 TQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLK 814
Cdd:COG4717   154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233

                         170
                  ....*....|....*..
gi 768015747  815 SQLVAQDDSQRLVEQEV 831
Cdd:COG4717   234 NELEAAALEERLKEARL 250
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 357-724 4.38e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 4.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  357 LRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAavkLSALNEALALDKVGLNQQ--LLQLEEENQSVCSRMEAA 434
Cdd:COG3096   290 LRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQD---YQAASDHLNLVQTALRQQekIERYQEDLEELTERLEEQ 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  435 EQARNALQVDLAEAEKRREALWEKNTHLEAQL-----------------QKAEEAGAELQADLRDIQEEKEEIQKKLSES 497
Cdd:COG3096   367 EEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyqqaldvqqtraiqyQQAVQALEKARALCGLPDLTPENAEDYLAAF 446

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  498 RHQQEAATTQLEQLHQ------EAKRQEEVLARAVQEKEALVREKAALEVRLQAVE--RDRQDLAEQLQGLssakellES 569
Cdd:COG3096   447 RAKEQQATEEVLELEQklsvadAARRQFEKAYELVCKIAGEVERSQAWQTARELLRryRSQQALAQRLQQL-------RA 519

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  570 SLFEAQQQnsvievtkgqLEVQIQTVTQAKEVIQGEVRCL--KLELDTERSQAEQERDAAARQLAQAeQEGKTALEQQKA 647
Cdd:COG3096   520 QLAELEQR----------LRQQQNAERLLEEFCQRIGQQLdaAEELEELLAELEAQLEELEEQAAEA-VEQRSELRQQLE 588

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  648 AHEKEVNQLRekwEKERSWHqqelaKALESLEREKMELEMRLKEQQTEMEAIQ--AQREEERTQAESALCQMQLETEKE 724
Cdd:COG3096   589 QLRARIKELA---ARAPAWL-----AAQDALERLREQSGEALADSQEVTAAMQqlLEREREATVERDELAARKQALESQ 659
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1847-2024 4.43e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1847 EELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQERE--EEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALP 1924
Cdd:COG4913   262 ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEelRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLE 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1925 hshktspmeeqslkldslepRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDS 2004
Cdd:COG4913   342 --------------------QLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE 401

                         170       180
                  ....*....|....*....|
gi 768015747 2005 EQQRLQDELELTRRALEKER 2024
Cdd:COG4913   402 ALEEALAEAEAALRDLRREL 421
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
629-855 4.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  629 RQLAQAEQEGKTALEQQKAahekeVNQLREKWEKerswhQQELAKALESLEREKMELemRLKEQQTEMEAIQAQREEERT 708
Cdd:COG4913   235 DDLERAHEALEDAREQIEL-----LEPIRELAER-----YAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRA 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  709 QAESALCQMQlETEKERVSLLETLLQTQKELADAS-QQLERLRQDMKVQKLKEQETTGILQtQLQEAQRELKEAARQHRD 787
Cdd:COG4913   303 ELARLEAELE-RLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRA-RLEALLAALGLPLPASAE 380

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768015747  788 DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQddsqrlvEQEVQEKLREtqeynriqkeLEREKASL 855
Cdd:COG4913   381 EFAALRAEAAALLEALEEELEALEEALAEAEAA-------LRDLRRELRE----------LEAEIASL 431
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
178-705 4.67e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 4.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  178 DYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAG---------- 247
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKevkeleelke 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  248 -------QTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVN------VELQLQGDSAQGQKEEQQEELHL 314
Cdd:PRK03918  239 eieelekELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekaeeyIKLSEFYEEYLDELREIEKRLSR 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  315 AVRERERLQEMLMGLEAKQSE------SLSELITLREALESSHLEGELLRQEQT---------------EVTAALARAEQ 373
Cdd:PRK03918  319 LEEEINGIEERIKELEEKEERleelkkKLKELEKRLEELEERHELYEEAKAKKEelerlkkrltgltpeKLEKELEELEK 398

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  374 SIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARnaLQVDLAEAEKRRE 453
Cdd:PRK03918  399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR--IEKELKEIEEKER 476

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  454 ALWEKNTHLEAQLQKAEEAGAelqadLRDIQEEKEEIQKKLSESRHQQ-EAATTQLEQLHQEA---KRQEEVLARAVQEK 529
Cdd:PRK03918  477 KLRKELRELEKVLKKESELIK-----LKELAEQLKELEEKLKKYNLEElEKKAEEYEKLKEKLiklKGEIKSLKKELEKL 551

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  530 EALVREKAALEVRLQAVERDRQDLAEQLQ--GLSSAKELlesslfeaqqqnsviEVTKGQLEVQIQTVTQAKEVIQgEVR 607
Cdd:PRK03918  552 EELKKKLAELEKKLDELEEELAELLKELEelGFESVEEL---------------EERLKELEPFYNEYLELKDAEK-ELE 615

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  608 CLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKaLESLEREKMELEM 687
Cdd:PRK03918  616 REEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAE-LEELEKRREEIKK 694

                         570
                  ....*....|....*...
gi 768015747  688 RLKEQQTEMEAIQAQREE 705
Cdd:PRK03918  695 TLEKLKEELEEREKAKKE 712
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1054-1746 4.87e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.42  E-value: 4.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1054 QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQ 1133
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQ 427

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1134 ----RMEAQGERELLQAAKENLTAQVEHLQAAVVEAR-AQASAAGILE--EDLRTARSALKL--KNEEVESERERAQALQ 1204
Cdd:TIGR00606  428 adeiRDEKKGLGRTIELKKEILEKKQEELKFVIKELQqLEGSSDRILEldQELRKAERELSKaeKNSLTETLKKEVKSLQ 507

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1205 -EQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSL--DLKKRNQEVDLQQEQIQELE 1281
Cdd:TIGR00606  508 nEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgYFPNKKQLEDWLHSKSKEIN 587

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1282 KCRSVLEHLPMAVQEREQkltvQREQIRELEKDRETQRNVLEHQLLEL---EKKDQMIESQRGQVQDLKKQLV-----TL 1353
Cdd:TIGR00606  588 QTRDRLAKLNKELASLEQ----NKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEEIEKSSKQRAmlagaTA 663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1354 ECLALELEENHHKMECQQKLIKELEGQRETQRVA------LTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERD 1427
Cdd:TIGR00606  664 VYSQFITQLTDENQSCCPVCQRVFQTEAELQEFIsdlqskLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1428 QEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIleedlEQIKLSLRERGRELTTQRQLMQer 1507
Cdd:TIGR00606  744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIM-----ERFQMELKDVERKIAQQAAKLQ-- 816

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1508 aeegkgpSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGEtsllLSQREQEIVVLQQQLQE 1587
Cdd:TIGR00606  817 -------GSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE----LKSEKLQIGTNLQRRQQ 885

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1588 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQAR 1667
Cdd:TIGR00606  886 FEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQ 965

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747  1668 RLEEELAVEgrRVQALEEVLGDLRAESREQEKAllalqqQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1746
Cdd:TIGR00606  966 DGKDDYLKQ--KETELNTVNAQLEECEKHQEKI------NEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEE 1036
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
370-582 5.29e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 5.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  370 RAEQSIAELSSSENTLKTEVADLRAaavKLSALNEALAldKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAE 449
Cdd:COG3206   165 NLELRREEARKALEFLEEQLPELRK---ELEEAEAALE--EFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  450 KRREALWEKN----------------THLEAQLQKAEEAGAELQADLRD----IQEEKEEIQKKLSESRHQQEAATTQLE 509
Cdd:COG3206   240 ARLAALRAQLgsgpdalpellqspviQQLRAQLAELEAELAELSARYTPnhpdVIALRAQIAALRAQLQQEAQRILASLE 319

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747  510 QLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIE 582
Cdd:COG3206   320 AELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRVID 392
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
420-711 5.80e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.51  E-value: 5.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  420 LEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 499
Cdd:COG4372    29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  500 QQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 579
Cdd:COG4372   109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  580 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK 659
Cdd:COG4372   189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 768015747  660 WEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAE 711
Cdd:COG4372   269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAA 320
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1420-1648 6.36e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 6.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1420 ARELQERDQEVKSQREQIEELQRQKEHLTQdLERRDQELMLQKERIQVLEDQRTRQTkiLEEDLEQIKLsLRERGRELTT 1499
Cdd:COG4913   227 ADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALR--LWFAQRRLEL-LEAELEELRA 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1500 QRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKE-KEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEI 1578
Cdd:COG4913   303 ELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEF 382

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1579 VVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQA 1648
Cdd:COG4913   383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
PRK11281 PRK11281
mechanosensitive channel MscK;
690-958 6.46e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.29  E-value: 6.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  690 KEQQTEMEAIQAQREEErtqAESALCQMQLET-----------EKERVSLLETLLQTQKELADASQQLERLRQDMKVQKL 758
Cdd:PRK11281   39 ADVQAQLDALNKQKLLE---AEDKLVQQDLEQtlalldkidrqKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  759 KEQETTgilqtqlqeaqrelkeaarqhrdDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET 838
Cdd:PRK11281  116 ETLSTL-----------------------SLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  839 QEYNRIQKELEREKASLTLS---LMEKEQRLLVLQeaDSIRQQELSA--LRQDMQEAQ-----GEQKELSAQMELLRQEV 908
Cdd:PRK11281  173 QQIRNLLKGGKVGGKALRPSqrvLLQAEQALLNAQ--NDLQRKSLEGntQLQDLLQKQrdyltARIQRLEHQLQLLQEAI 250

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 768015747  909 KEKEadfLAQEAQLLEELEASHITEQQLRASLWAQEAkAAQLQLR---LRSTE 958
Cdd:PRK11281  251 NSKR---LTLSEKTVQEAQSQDEAARIQANPLVAQEL-EINLQLSqrlLKATE 299
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 839-941 6.51e-04

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 44.94  E-value: 6.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  839 QEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADsirqQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQ 918
Cdd:PRK11448  142 NLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQ----QELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQK 217

                          90       100       110
                  ....*....|....*....|....*....|..
gi 768015747  919 EAQL---------LEELEASHITEQQLRASLW 941
Cdd:PRK11448  218 RKEItdqaakrleLSEEETRILIDQQLRKAGW 249
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 483-761 6.66e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 6.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   483 IQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEvlaravQEKEALVREKAALEVRLQAVERDRQDLAEQ--LQGL 560
Cdd:pfam17380  301 LRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAE------QERMAMERERELERIRQEERKRELERIRQEeiAMEI 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   561 SSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQER---DAAARQLAQAEQE 637
Cdd:pfam17380  375 SRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRrleEERAREMERVRLE 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   638 GKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALES--LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 715
Cdd:pfam17380  455 EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRkiLEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEER 534

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 768015747   716 QMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQ 761
Cdd:pfam17380  535 RREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQ 580
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
539-794 7.30e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 7.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  539 LEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIevtkgQLEVQIQTVTQAKEviqgevrclklELDTERS 618
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV-----DLSEEAKLLLQQLS-----------ELESQLA 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  619 QAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQlrekwekerswhqqELAKALESLEREKMELEMRLKEQQTEMEA 698
Cdd:COG3206   230 EARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQ--------------QLRAQLAELEAELAELSARYTPNHPDVIA 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  699 IQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQdmkvqklkeqettgiLQTQLQEAQREL 778
Cdd:COG3206   296 LRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE---------------LEAELRRLEREV 360

                         250
                  ....*....|....*.
gi 768015747  779 KEAARQHRDDLAALQE 794
Cdd:COG3206   361 EVARELYESLLQRLEE 376
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1128-1510 7.39e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 7.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1128 RRAELQRMEAQGERELlQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEevesererAQALQEqg 1207
Cdd:COG3096   279 ERRELSERALELRREL-FGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQT--------ALRQQE-- 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1208 elKVAQgkaLQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ-------EQIQEL 1280
Cdd:COG3096   348 --KIER---YQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraiqyqQAVQAL 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1281 EKCRSVLEHLPMA---VQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIES-----QRGQVQDLKKQLVT 1352
Cdd:COG3096   423 EKARALCGLPDLTpenAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiagevERSQAWQTARELLR 502

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1353 LECLALELEENHHKMECQQK-LIKELEGQRETQRValthltldLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVK 1431
Cdd:COG3096   503 RYRSQQALAQRLQQLRAQLAeLEQRLRQQQNAERL--------LEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAA 574

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1432 SQREQIEELQRQKEHLTQD---LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLrERGRELTTQRQLMQERA 1508
Cdd:COG3096   575 EAVEQRSELRQQLEQLRARikeLAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLL-EREREATVERDELAARK 653


                  ..
gi 768015747 1509 EE 1510
Cdd:COG3096   654 QA 655
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1087-1579 7.64e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.83  E-value: 7.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1087 DLQRQLSQNQEEKSKWEGKQNSLESELMELhetmASLQSRLRRAELQRMEAQGERELLQAAKENLTAQvehLQAAVVEAR 1166
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRL----SHLHFGYKSDETLIASRQEERQETSAELNQLLRT---LDDQWKEKR 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1167 AQASAagileeDLRTARSALKLKNEEVESERERAQALQEQGelkVAQGKALQENLALLTQTLAEREEEVETLRGQIQELE 1246
Cdd:pfam12128  304 DELNG------ELSAADAAVAKDRSELEALEDQHGAFLDAD---IETAAADQEQLPSWQSELENLEERLKALTGKHQDVT 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1247 KQREMQKAALEL-LSLDLKKRNQEVDLQQEQI-QELEKCRSVLEHLPMAVQER-EQKLTVQREQIRELE------KDRET 1317
Cdd:pfam12128  375 AKYNRRRSKIKEqNNRDIAGIKDKLAKIREARdRQLAVAEDDLQALESELREQlEAGKLEFNEEEYRLKsrlgelKLRLN 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1318 QRNVLEHQLLELEKKDQMIESQRGQVQDLKKqlvtleclaleleenhhKMECQQKLIKELEGQRETQRVALTHLTLDLEE 1397
Cdd:pfam12128  455 QATATPELLLQLENFDERIERAREEQEAANA-----------------EVERLQSELRQARKRRDQASEALRQASRRLEE 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1398 RSQELQAQSSQ--------IHDL--------ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRD------ 1455
Cdd:pfam12128  518 RQSALDELELQlfpqagtlLHFLrkeapdweQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDvpewaa 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1456 QELMLQKERIQVLEDQRTRQTKI--LEEDLEQIKLSLRERGRELTTQRQ-LMQERAEEGKGPSKAQRGSLEHMKLILRDK 1532
Cdd:pfam12128  598 SEEELRERLDKAEEALQSAREKQaaAEEQLVQANGELEKASREETFARTaLKNARLDLRRLFDEKQSEKDKKNKALAERK 677

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 768015747  1533 EKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIV 1579
Cdd:pfam12128  678 DSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVE 724
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1083-1324 7.78e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.89  E-value: 7.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1083 TELQDLQRQLSqnqeEKSKWEGKQNSLESELMELH-------------ETMASLQSRLRRAELQRMEAQG--------ER 1141
Cdd:PLN02939  153 QALEDLEKILT----EKEALQGKINILEMRLSETDariklaaqekihvEILEEQLEKLRNELLIRGATEGlcvhslskEL 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1142 ELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDlrtaRSALKLKNEEVESERERAQA-LQEQGELKVAQGKALQEN 1220
Cdd:PLN02939  229 DVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKE----RSLLDASLRELESKFIVAQEdVSKLSPLQYDCWWEKVEN 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1221 LALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDlKKRNQEVDLQQEQIQELEkcrsvlEHLPMAVQEREQK 1300
Cdd:PLN02939  305 LQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVS-KFSSYKVELLQQKLKLLE------ERLQASDHEIHSY 377

                         250       260
                  ....*....|....*....|....*....
gi 768015747 1301 LTVQREQIRELEKD-----RETQRNVLEH 1324
Cdd:PLN02939  378 IQLYQESIKEFQDTlsklkEESKKRSLEH 406
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 518-748 8.40e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  518 QEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQ 597
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  598 AKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGkTALEQQKAAHEKEVNQLREKwekerswhQQELAKALES 677
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-QYLKYLAPARREQAEELRAD--------LAELAALRAE 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768015747  678 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAlcQMQLETEKERvslLETLLQTQKELADASQQLER 748
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAERQKLLARL--EKELAELAAE---LAELQQEAEELEALIARLEA 234
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
353-650 8.42e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 8.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  353 EGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALdkvgLNQQLLQLEEENQSVCSRME 432
Cdd:COG4372    22 TGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQ----LEEELEELNEQLQAAQAELA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  433 AAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLH 512
Cdd:COG4372    98 QAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALS 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  513 QEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQI 592
Cdd:COG4372   178 EAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVIL 257

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 768015747  593 QTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHE 650
Cdd:COG4372   258 KEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALED 315
46 PHA02562
endonuclease subunit; Provisional
 642-868 8.47e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 8.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  642 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEmRLKEQQTEMEAIQaqreEERTQAESALCQ--MQL 719
Cdd:PHA02562  193 IQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIE-ELTDELLNLVMDI----EDPSAALNKLNTaaAKI 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  720 ETEKERVSLLETLLQTQKELADASQQLERlrQDMKVQKLKEQETTgiLQTQLQEAQrelkeaarQHRDDLAALQEESSSL 799
Cdd:PHA02562  268 KSKIEQFQKVIKMYEKGGVCPTCTQQISE--GPDRITKIKDKLKE--LQHSLEKLD--------TAIDELEEIMDEFNEQ 335

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747  800 LQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQ----EKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLV 868
Cdd:PHA02562  336 SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEelqaEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIV 408
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 780-1600 8.71e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 8.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   780 EAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKAsltlSL 859
Cdd:TIGR00606  189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLS----KI 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   860 MEKEQRLLVLQEADSIRQQELSALRQDMQEA-QGEQKELSAQMELLRQEVKEKEADF---------LAQEAQLLEELEas 929
Cdd:TIGR00606  265 MKLDNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELvdcqrelekLNKERRLLNQEK-- 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   930 hiTEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQAlGSVCESRPELSGGGDSAP 1009
Cdd:TIGR00606  343 --TELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIE-RQEDEAKTAAQLCADLQS 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1010 SVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLrDQVQKLEERLTDTEAE--KSQVHTELQD 1087
Cdd:TIGR00606  420 KERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSS-DRILELDQELRKAERElsKAEKNSLTET 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1088 LQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARA 1167
Cdd:TIGR00606  499 LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDW 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1168 QASaagiLEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAErEEEVETLRGQIQELEK 1247
Cdd:TIGR00606  579 LHS----KSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSK 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1248 QREMQKAALELLSLDLKKRNQE----VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLE 1323
Cdd:TIGR00606  654 QRAMLAGATAVYSQFITQLTDEnqscCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAP 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1324 HQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELegQRETQRVALTHLTLDLEERSQELQ 1403
Cdd:TIGR00606  734 GRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVC--LTDVTIMERFQMELKDVERKIAQQ 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1404 AQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQEL-MLQKERIQVLEDQRTRQTkiLEED 1482
Cdd:TIGR00606  812 AAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTnELKSEKLQIGTNLQRRQQ--FEEQ 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1483 LEQIKLSLRERGRELTTQRqlmqeraEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHR 1562
Cdd:TIGR00606  890 LVELSTEVQSLIREIKDAK-------EQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIEN 962

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 768015747  1563 KVGE-TSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQ 1600
Cdd:TIGR00606  963 KIQDgKDDYLKQKETELNTVNAQLEECEKHQEKINEDMR 1001
PRK11281 PRK11281
mechanosensitive channel MscK;
669-941 9.29e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 9.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  669 QELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKErvSLLETLLQTQKELADASQQLER 748
Cdd:PRK11281   76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLA--QTLDQLQNAQNDLAEYNSQLVS 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  749 lrqdmkvqklkeqettgiLQTQLQEAQRELKEAARQhrddlaaLQEESSSLLQDKMDLQKQVEDLKSQLVAQddsQRLVE 828
Cdd:PRK11281  154 ------------------LQTQPERAQAALYANSQR-------LQQIRNLLKGGKVGGKALRPSQRVLLQAE---QALLN 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  829 QEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEAdsIRQQELSALRQDMQEAQGEQKELSAQM-ELLRQE 907
Cdd:PRK11281  206 AQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEA--INSKRLTLSEKTVQEAQSQDEAARIQAnPLVAQE 283

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 768015747  908 --VKEKEADFLAQEAQLLEELeashiTEQQLRASLW 941
Cdd:PRK11281  284 leINLQLSQRLLKATEKLNTL-----TQQNLRVKNW 314
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 251-475 1.06e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  251 DLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLmgle 330
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  331 AKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAElsssenTLKTEVADLRAAAVKLSALNEALALDK 410
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP------ARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  411 VGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAE 475
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 485-784 1.09e-03

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 43.75  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   485 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAK 564
Cdd:pfam13868   29 AEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEEREQKRQEEYEEKLQEREQMDEIVE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   565 ELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVR---------CLKLELDTERSQAEQERDAAARQLAQAE 635
Cdd:pfam13868  109 RIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEReederileyLKEKAEREEEREAEREEIEEEKEREIAR 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   636 QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 715
Cdd:pfam13868  189 LRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEQIELKERRLAEEAEREEEEFERMLR 268

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747   716 QMQLETEKERVSLLETLLQtQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQ 784
Cdd:pfam13868  269 KQAEDEEIEQEEAEKRRMK-RLEHRRELEKQIEEREEQRAAEREEELEEGERLREEEAERRERIEEERQ 336
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 346-786 1.13e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.27  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  346 ALESSHLEGELLRQEQTEVTAALARAEQSIAE-LSSSENTLKTEVADLRAAAVKLSALNEALALDKvGLNQQLLQLEEEN 424
Cdd:PRK10929   17 AYAATAPDEKQITQELEQAKAAKTPAQAEIVEaLQSALNWLEERKGSLERAKQYQQVIDNFPKLSA-ELRQQLNNERDEP 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  425 QSVCSRMEAAEQARNALQVDLAEAEKRRealweknthleaQLQKAEEAGAELQADLRDIQEEKEEIQKKLS--ESRHQ-Q 501
Cdd:PRK10929   96 RSVPPNMSTDALEQEILQVSSQLLEKSR------------QAQQEQDRAREISDSLSQLPQQQTEARRQLNeiERRLQtL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  502 EAATTQLEQLhQEAKRQEEVLARAVQEKEAlvrEKAALEVR-LQAVERDRQDLAE-QLQGLSSAKELLESSLFEAQQQNs 579
Cdd:PRK10929  164 GTPNTPLAQA-QLTALQAESAALKALVDEL---ELAQLSANnRQELARLRSELAKkRSQQLDAYLQALRNQLNSQRQRE- 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  580 vievTKGQLEVQIQTVTQAKEVIQGEVRCLKL--ELDTERSQAEQERDAAARQLAQAEQEgktaLEQQKAAhekeVNQLR 657
Cdd:PRK10929  239 ----AERALESTELLAEQSGDLPKSIVAQFKInrELSQALNQQAQRMDLIASQQRQAASQ----TLQVRQA----LNTLR 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  658 EK--WEKERSwhqqelakAL-ESLEREKMELEMRLKEQQ--TEMEAIQAQR---EE--ERTQAESALCQ---MQLETEKE 724
Cdd:PRK10929  307 EQsqWLGVSN--------ALgEALRAQVARLPEMPKPQQldTEMAQLRVQRlryEDllNKQPQLRQIRQadgQPLTAEQN 378

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768015747  725 RVslLETLLQTQKELADA------SQQLErlrqdmkVQKLKeqettgILQTQLQEAQRELKEAArqHR 786
Cdd:PRK10929  379 RI--LDAQLRTQRELLNSllsggdTLILE-------LTKLK------VANSQLEDALKEVNEAT--HR 429
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1606-1830 1.35e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1606 AQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEE 1685
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1686 VLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQ 1765
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747 1766 EALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLR 1830
Cdd:COG4942   178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
767-965 1.36e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  767 LQTQLQEAQRELKEAarqhRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQK 846
Cdd:COG4372    43 LQEELEQLREELEQA----REELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELE 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  847 ELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEEL 926
Cdd:COG4372   119 ELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEK 198

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 768015747  927 EASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALA 965
Cdd:COG4372   199 EEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSA 237
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1233-1453 1.61e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1233 EEVETLRGQIQELEKQREmQKAALEllslDLKKRNQEVDLQQEQIQELEKCRSVLEHlpmavQEREQKLTVQREQIRELE 1312
Cdd:COG4913   232 EHFDDLERAHEALEDARE-QIELLE----PIRELAERYAAARERLAELEYLRAALRL-----WFAQRRLELLEAELEELR 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1313 KDR---ETQRNVLEHQLLELEKKDQMIESQR-----GQVQDLKKQLVTLeclaleleenhhkmecqQKLIKELEGQRETQ 1384
Cdd:COG4913   302 AELarlEAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERL-----------------ERELEERERRRARL 364

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747 1385 RVALTHLTLDLEERSQELQAQSSQIHDLeshSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLER 1453
Cdd:COG4913   365 EALLAALGLPLPASAEEFAALRAEAAAL---LEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1529-1750 2.19e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1529 LRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQR 1608
Cdd:COG4942    36 IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1609 ALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEqahmtlkerhgELQDHKEQARRLEEELAVEGRRVQALEEVLG 1688
Cdd:COG4942   116 LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-----------ELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768015747 1689 DLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSS 1750
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 446-648 2.40e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 2.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  446 AEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVL--- 522
Cdd:COG3883    12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELger 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  523 ARAVQEKEALVREKAALEV---------RLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQ 593
Cdd:COG3883    92 ARALYRSGGSVSYLDVLLGsesfsdfldRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  594 TVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAA 648
Cdd:COG3883   172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAA 226
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 485-858 2.67e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 42.75  E-value: 2.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   485 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAK 564
Cdd:pfam19220   20 EDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   565 ELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLEL---DTERSQAEQERDAAARQLAQAEQEGKta 641
Cdd:pfam19220  100 REAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAqaaEKALQRAEGELATARERLALLEQENR-- 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   642 leQQKAAHEKEVNQLREKWEKerswhQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERT--QAESALCQMQL 719
Cdd:pfam19220  178 --RLQALSEEQAAELAELTRR-----LAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEahRAERASLRMKL 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   720 ETEKERVSLLETLLQ----TQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQhRDDLAALQEE 795
Cdd:pfam19220  251 EALTARAAATEQLLAearnQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQRA-RAELEERAEM 329

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768015747   796 SSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEynRIQKELEREKASLTLS 858
Cdd:pfam19220  330 LTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANR--RLKEELQRERAERALA 390
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 421-936 2.97e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   421 EEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQ-------KAEEAGAELQADLRDIQEEKEEIQKK 493
Cdd:pfam01576    4 EEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQaetelcaEAEEMRARLAARKQELEEILHELESR 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   494 LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFE 573
Cdd:pfam01576   84 LEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISE 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   574 AQQQ-NSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTA-LEQQKAAHEK 651
Cdd:pfam01576  164 FTSNlAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAeLRAQLAKKEE 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   652 EVNQLREKWEKERSWHQQELAKAleslerekMELEMRLKEQQTEMEAIQAQREeertQAESALCQMQLETEKERVSLLET 731
Cdd:pfam01576  244 ELQAALARLEEETAQKNNALKKI--------RELEAQISELQEDLESERAARN----KAEKQRRDLGEELEALKTELEDT 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   732 LLQTqkeladASQQLERLRQDMKVQKLKE--QETTGILQTQLQE-------AQRELKEAARQHRDDLAALQEESSSLLQD 802
Cdd:pfam01576  312 LDTT------AAQQELRSKREQEVTELKKalEEETRSHEAQLQEmrqkhtqALEELTEQLEQAKRNKANLEKAKQALESE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   803 KMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSA 882
Cdd:pfam01576  386 NAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSS 465

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 768015747   883 LRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQL 936
Cdd:pfam01576  466 LESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQL 519
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1845-2122 3.10e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.75  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1845 RDEELRHQQEREQLLE---KSLAQRVQENMIQEKQNLGQ-EREEEEIRGLHQSVRELQLTLAQKEQEILEL-RETQQRNN 1919
Cdd:TIGR02169  207 REKAERYQALLKEKREyegYELLKEKEALERQKEAIERQlASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1920 LEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAR------EIE-WREKAQDLALSLAQTKASVSSLQEVA 1992
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEidkllaEIEeLEREIEEERKRRDKLTEEYAELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1993 MFLQASVLERDSEQQRLQDELELTRRALEK-ERLHSPGATSTAELGSRGEQGVQLG-----EVSGVEAEPSPDGMEKQSW 2066
Cdd:TIGR02169  367 EDLRAELEEVDKEFAETRDELKDYREKLEKlKREINELKRELDRLQEELQRLSEELadlnaAIAGIEAKINELEEEKEDK 446

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747  2067 RQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRA-AQAGSLE 2122
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeAQARASE 503
PTZ00491 PTZ00491
major vault protein; Provisional
 622-742 3.37e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 42.70  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  622 QERDAAARQLAQA-EQEGKTALEQQKAAHEKEVNQLREKWEKERSwHQQELAKALESLEREKMELEMRLKEQQTEMEAIQ 700
Cdd:PTZ00491  662 KSQEAAARHQAELlEQEARGRLERQKMHDKAKAEEQRTKLLELQA-ESAAVESSGQSRAEALAEAEARLIEAEAEVEQAE 740

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 768015747  701 AQREEERTQAESALCQMQLETEKE---RVSLLETLLQTQKELADA 742
Cdd:PTZ00491  741 LRAKALRIEAEAELEKLRKRQELEleyEQAQNELEIAKAKELADI 785
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
243-511 3.79e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 42.37  E-value: 3.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  243 DTLAGQTVDLQgEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQlqgdsaqgqkeeqqeELHLAVRERERL 322
Cdd:COG0497   148 DAFAGLEELLE-EYREAYRAWRALKKELEELRADEAERARELDLLRFQLEELE---------------AAALQPGEEEEL 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  323 QEmlmgleakQSESLSELITLREALESSHlegELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSAL 402
Cdd:COG0497   212 EE--------ERRRLSNAEKLREALQEAL---EALSGGEGGALDLLGQALRALERLAEYDPSLAELAERLESALIELEEA 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  403 NEALA--LDKVGLNQQLLQLEEEnqsvcsRMEAAEQARNALQVDLAE----AEKRREALweknthleAQLQKAEEAGAEL 476
Cdd:COG0497   281 ASELRryLDSLEFDPERLEEVEE------RLALLRRLARKYGVTVEEllayAEELRAEL--------AELENSDERLEEL 346

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 768015747  477 QADLRDIQEEKEEIQKKLSESRHQ-----QEAATTQLEQL 511
Cdd:COG0497   347 EAELAEAEAELLEAAEKLSAARKKaakklEKAVTAELADL 386
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 226-438 4.05e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  226 EEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQK 305
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  306 EEQQEEL--HLAVRERERLQEMLMGLEAKQS--ESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSS 381
Cdd:COG4942   100 EAQKEELaeLLRALYRLGRQPPLALLLSPEDflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747  382 ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQAR 438
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
46 PHA02562
endonuclease subunit; Provisional
 386-570 4.20e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 4.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  386 KTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRrEALWEKNTHL--- 462
Cdd:PHA02562  212 GENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKV-IKMYEKGGVCptc 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  463 -------EAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAAT---TQLEQLHQ-------EAKRQEEVLARA 525
Cdd:PHA02562  291 tqqisegPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLelkNKISTNKQslitlvdKAKKVKAAIEEL 370

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 768015747  526 VQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESS 570
Cdd:PHA02562  371 QAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLKDS 415
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 468-792 4.36e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 42.15  E-value: 4.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  468 KAEEAGAelqADLRDIQEEKEEIQKKLSESRHQ-----QEAATTQLEQLHQEAKRQ--EEVLARAVQEKEALVREKAAle 540
Cdd:PLN03229  422 KKREAVK---TPVRELEGEVEKLKEQILKAKESsskpsELALNEMIEKLKKEIDLEytEAVIAMGLQERLENLREEFS-- 496

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  541 vrlqavERDRQD------LAEQLQGLssaKELLESSLFEAQQQNSVievtKGQLEVqIQTVTQAKEVIQGEVRCLKLELD 614
Cdd:PLN03229  497 ------KANSQDqlmhpvLMEKIEKL---KDEFNKRLSRAPNYLSL----KYKLDM-LNEFSRAKALSEKKSKAEKLKAE 562

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  615 TERSQAEQERDAAARQLAQAEqegKTALEQQKAAHEKEVNQ-LREKWEKERSWHQQELAKALESLEREKMELEMRLKE-- 691
Cdd:PLN03229  563 INKKFKEVMDRPEIKEKMEAL---KAEVASSGASSGDELDDdLKEKVEKMKKEIELELAGVLKSMGLEVIGVTKKNKDta 639

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  692 QQTEMEAIQAQREEERTQAESALCQMQLETE-KERVSLL--ETLLQTQKELADASQQLERLRQdmkvqKLKEQETTGILQ 768
Cdd:PLN03229  640 EQTPPPNLQEKIESLNEEINKKIERVIRSSDlKSKIELLklEVAKASKTPDVTEKEKIEALEQ-----QIKQKIAEALNS 714

                         330       340
                  ....*....|....*....|....
gi 768015747  769 TQLQEAQRELKEAARQHRDDLAAL 792
Cdd:PLN03229  715 SELKEKFEELEAELAAARETAAES 738
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1413-1506 4.37e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.15  E-value: 4.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1413 ESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQEL---------MLQKERIQVLEDqrtRQTKILEEDL 1483
Cdd:COG2433   398 EREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIerlerelseARSEERREIRKD---REISRLDREI 474

                          90       100
                  ....*....|....*....|....*.
gi 768015747 1484 EQIKLSL---RERGRELTTQRQLMQE 1506
Cdd:COG2433   475 ERLERELeeeRERIEELKRKLERLKE 500
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
89-577 4.90e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 4.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   89 LLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQ----------EEKLSLQQVIKDITQVMVEEGDNIA 158
Cdd:COG4913   253 LLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELeelraelarlEAELERLEARLDALREELDELEAQI 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  159 QGSGHENSLELDSSIfsqfdyQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKl 238
Cdd:COG4913   333 RGNGGDRLEQLEREI------ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE- 405

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  239 tgERDTLAGQTVDLQGEVDSLSKERELLQK-----------AREELRQQLEV---------------LEQEAWRLrrvNV 292
Cdd:COG4913   406 --ALAEAEAALRDLRRELRELEAEIASLERrksniparllaLRDALAEALGLdeaelpfvgelievrPEEERWRG---AI 480

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  293 ELQLQG--------DSAQGQKEEQQEELHLAVR---ERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQ-- 359
Cdd:COG4913   481 ERVLGGfaltllvpPEHYAAALRWVNRLHLRGRlvyERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRfd 560

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  360 -EQTEVTAALARAEQSI--AELSSSENTL---KTEVADLRA------AAVKLSALNEALAldkvGLNQQLLQLEEENQSV 427
Cdd:COG4913   561 yVCVDSPEELRRHPRAItrAGQVKGNGTRhekDDRRRIRSRyvlgfdNRAKLAALEAELA----ELEEELAEAEERLEAL 636

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  428 CSRMEAAEQARNALQ---------VDLAEAEKRREALWEKNTHLEA---QLQKAEEAGAELQADLRDIQEEKEEIQKKLS 495
Cdd:COG4913   637 EAELDALQERREALQrlaeyswdeIDVASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIG 716

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  496 ESRHQQEAATTQLEQLhqeAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQ 575
Cdd:COG4913   717 RLEKELEQAEEELDEL---QDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAM 793


                  ..
gi 768015747  576 QQ 577
Cdd:COG4913   794 RA 795
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
808-1260 5.31e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.06  E-value: 5.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  808 KQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLslMEKEQRLLVLQEADSIRQQELSALRQDM 887
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK--LEKLLQLLPLYQELEALEAELAELPERL 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  888 QEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAE 967
Cdd:COG4717   149 EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  968 QQPGNQAQAQAQLASLYSALQQALGsvcesrpelsgggdSAPSVWGLEPDQNGARSLFKRGPLLTALsaeaVASALHKLH 1047
Cdd:COG4717   229 LEQLENELEAAALEERLKEARLLLL--------------IAAALLALLGLGGSLLSLILTIAGVLFL----VLGLLALLF 290

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1048 QDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRL 1127
Cdd:COG4717   291 LLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQ 370

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1128 RRAELQRMEAQGERELLQAAKENLTAQVEhLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQG 1207
Cdd:COG4717   371 EIAALLAEAGVEDEEELRAALEQAEEYQE-LKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELE 449

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 768015747 1208 ELKVAQGKALQENLALLT-QTLAEREEEVETLRGQIQELEKQREMQKAALELLS 1260
Cdd:COG4717   450 ELREELAELEAELEQLEEdGELAELLQELEELKAELRELAEEWAALKLALELLE 503
mukB PRK04863
chromosome partition protein MukB;
644-967 5.85e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 5.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  644 QQKAAHEKEVNQLREKWEKERSWHQqELAKALESLEREKMELEMRLKE----QQTEMEAIQAQREEERTQAESALCQMQL 719
Cdd:PRK04863  286 EEALELRRELYTSRRQLAAEQYRLV-EMARELAELNEAESDLEQDYQAasdhLNLVQTALRQQEKIERYQADLEELEERL 364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  720 ETEKERVSLL-ETLLQTQKELADASQQLERLRQDMK--VQKLKEQETTGIlqtQLQEAQRELKEAARQ-HRDDLAAlqee 795
Cdd:PRK04863  365 EEQNEVVEEAdEQQEENEARAEAAEEEVDELKSQLAdyQQALDVQQTRAI---QYQQAVQALERAKQLcGLPDLTA---- 437

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  796 sssllqdkmdlqKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYN-----------RIQKELEREKASltlslmEKEQ 864
Cdd:PRK04863  438 ------------DNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHsqfeqayqlvrKIAGEVSRSEAW------DVAR 499

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  865 RLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEaqlleELEASHITEQQLRASLWAQE 944
Cdd:PRK04863  500 ELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDED-----ELEQLQEELEARLESLSESV 574

                         330       340
                  ....*....|....*....|...
gi 768015747  945 AKAAQLQLRLRSTESQLEALAAE 967
Cdd:PRK04863  575 SEARERRMALRQQLEQLQARIQR 597
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
587-991 5.98e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 5.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  587 QLEVQIQTVTQAKEVIQGEVRCLK-----LELDTERSQAEQERDAAARQLAQAEQEGKT--ALEQQKAAHEKEVNQLREK 659
Cdd:COG4717    99 ELEEELEELEAELEELREELEKLEkllqlLPLYQELEALEAELAELPERLEELEERLEElrELEEELEELEAELAELQEE 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  660 WEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKEL 739
Cdd:COG4717   179 LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAAL 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  740 ADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSsllqdkmdlqkQVEDLKSQLVA 819
Cdd:COG4717   259 LALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEL-----------EEEELEELLAA 327

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  820 QDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSA 899
Cdd:COG4717   328 LGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEEL 407

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  900 QMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQ 979
Cdd:COG4717   408 EEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRE 487

                         410
                  ....*....|..
gi 768015747  980 LASLYSALQQAL 991
Cdd:COG4717   488 LAEEWAALKLAL 499
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1293-1522 5.98e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1293 AVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQK 1372
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1373 LIKELEGQ--RETQRVALTHLTLDLEERSQELQAQSSQ--IHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLT 1448
Cdd:COG4942   101 AQKEELAEllRALYRLGRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768015747 1449 QDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK-GPSKAQRGSL 1522
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPaAGFAALKGKL 255
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 317-967 6.00e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.88  E-value: 6.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   317 RERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAA 396
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   397 VKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQ-ARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAE 475
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKsELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   476 LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAE 555
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLED 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   556 QLQGLSSAKELLESSLFEAqQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 635
Cdd:pfam02463  420 LLKEEKKEELEILEEEEES-IELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEER 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   636 QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 715
Cdd:pfam02463  499 SQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGAR 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   716 QMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEE 795
Cdd:pfam02463  579 KLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGL 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   796 SSSLLQDKMDLQKQVEDLKSQLVAQDdsqrlvEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSI 875
Cdd:pfam02463  659 AEKSEVKASLSELTKELLEIQELQEK------AESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   876 RQQELSALRQdMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLR 955
Cdd:pfam02463  733 KINEELKLLK-QKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650
                   ....*....|..
gi 768015747   956 STESQLEALAAE 967
Cdd:pfam02463  812 EEAELLEEEQLL 823
PTZ00121 PTZ00121
MAEBL; Provisional
 1073-1834 6.58e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 6.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1073 DTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME----AQGERELLQAAK 1148
Cdd:PTZ00121 1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEearkAEDAKRVEIARK 1159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1149 ENLTAQVEHLQAAVVEARAQASAAGI---------LEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQE 1219
Cdd:PTZ00121 1160 AEDARKAEEARKAEDAKKAEAARKAEevrkaeelrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1220 NLAlltqtlaeREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEhlpMAVQEREQ 1299
Cdd:PTZ00121 1240 EEA--------KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE---KKKADEAK 1308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1300 KLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLvtlECLALELEENHHKMECQQKLIKELEG 1379
Cdd:PTZ00121 1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA---EAAEEKAEAAEKKKEEAKKKADAAKK 1385

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1380 QRETQRVALthltlDLEERSQELQAQSSQIHDLESHSTVlARELQERDQEVKsqreQIEELQRQKEHltqdlERRDQELM 1459
Cdd:PTZ00121 1386 KAEEKKKAD-----EAKKKAEEDKKKADELKKAAAAKKK-ADEAKKKAEEKK----KADEAKKKAEE-----AKKADEAK 1450

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1460 LQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEcQ 1539
Cdd:PTZ00121 1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK-K 1529

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1540 QEHIHELQELKDQLEQQLQGLHRKVGEtsllLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEA 1619
Cdd:PTZ00121 1530 AEEAKKADEAKKAEEKKKADELKKAEE----LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1620 LQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEElavegRRVQALEEVlgdlRAESREQEK 1699
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE-----NKIKAAEEA----KKAEEDKKK 1676

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1700 AllalqqqcaEQAQEHEVETRALQDSwLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAhaalQGKE 1779
Cdd:PTZ00121 1677 A---------EEAKKAEEDEKKAAEA-LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE----AEED 1742

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 768015747 1780 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQED 1834
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 418-1155 6.70e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.88  E-value: 6.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   418 LQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGaELQADLRDIQEEKEEIQKKLSES 497
Cdd:TIGR00618  208 LCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLK-QLRARIEELRAQEAVLEETQERI 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   498 RHQQEAATTQLEQLHQEAKRQEevLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQ 577
Cdd:TIGR00618  287 NRARKAAPLAAHIKAVTQIEQQ--AQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVA 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   578 NSVIEVTKGQLEVQ--IQTVTQAKEVIQGEVRCLKLELDTERSQAEQE--RDAAARQLAQ--AEQEGKTALEQQKAAHEK 651
Cdd:TIGR00618  365 TSIREISCQQHTLTqhIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtRTSAFRDLQGqlAHAKKQQELQQRYAELCA 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   652 EVNQLREKWEKERSWHQQELAKALESLEREKMELEMrLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLET 731
Cdd:TIGR00618  445 AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQ-IHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNP 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   732 LLQTQKeladasqqLERLRQDMKVQKLKEQETTGILQTQLQEAQReLKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 811
Cdd:TIGR00618  524 GPLTRR--------MQRGEQTYAQLETSEEDVYHQLTSERKQRAS-LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   812 DLKSQLVAQD---DSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEaDSIRQQELSALRQDMQ 888
Cdd:TIGR00618  595 RLQDLTEKLSeaeDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQ-ERVREHALSIRVLPKE 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   889 EAQGEQKELSAQMELLRQEVKEKEADFLAQEA--QLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAA 966
Cdd:TIGR00618  674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLlrELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQAR 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747   967 EQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL 1046
Cdd:TIGR00618  754 TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQF 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1047 HQDLWKTQQTRDVLRDQVQKLEERltdteaekSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME--LHETMASLQ 1124
Cdd:TIGR00618  834 LSRLEEKSATLGEITHQLLKYEEC--------SKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIkfLHEITLYAN 905

                          730       740       750
                   ....*....|....*....|....*....|.
gi 768015747  1125 SRLRRAELQRMEAQGERELLQAAKENLTAQV 1155
Cdd:TIGR00618  906 VRLANQSEGRFHGRYADSHVNARKYQGLALL 936
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 668-1271 7.23e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.71  E-value: 7.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  668 QQELAKALESLEREKMELEMRLKEQQTEMEAIQAQRE--EERTQAESALCQMQLETEKERVSLLE-TLLQTQKELADASQ 744
Cdd:PRK10246  218 VQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDElqQEASRRQQALQQALAAEEKAQPQLAAlSLAQPARQLRPHWE 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  745 QLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQ-DKMDLQKQVEDLKSQLVAQDDS 823
Cdd:PRK10246  298 RIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEhDRFRQWNNELAGWRAQFSQQTS 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  824 QRLVEQEVQEKLRETqeynrIQKELEREKASLTLSLMEK-------------EQRLLVLQEADSIRQQELSALRQDMQEA 890
Cdd:PRK10246  378 DREQLRQWQQQLTHA-----EQKLNALPAITLTLTADEVaaalaqhaeqrplRQRLVALHGQIVPQQKRLAQLQVAIQNV 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  891 QGEQKELSAQMELLRQEVKEKEADFLaqEAQLLEELEASHITEQQLRASLWA------------------QEAKAAQLQL 952
Cdd:PRK10246  453 TQEQTQRNAALNEMRQRYKEKTQQLA--DVKTICEQEARIKDLEAQRAQLQAgqpcplcgstshpaveayQALEPGVNQS 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  953 RLRSTESQLEALAAE------------QQPGNQAQAQAQLASLYSALQQALGSVCES-RPELSGGGDSAPSVWGLEPDQN 1019
Cdd:PRK10246  531 RLDALEKEVKKLGEEgaalrgqldaltKQLQRDESEAQSLRQEEQALTQQWQAVCASlNITLQPQDDIQPWLDAQEEHER 610

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1020 GARSLFKRGPLLTALSAEAvasalHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKS-------------QVHTELQ 1086
Cdd:PRK10246  611 QLRLLSQRHELQGQIAAHN-----QQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASwlatrqqeaqswqQRQNELT 685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1087 DLQRQLSQNQ-------EEKSKWEGKQNSLESELMELHETMASLQSRLrrAELQRMEAQgERELLQAAkenlTAQVEHLQ 1159
Cdd:PRK10246  686 ALQNRIQQLTplletlpQSDDLPHSEETVALDNWRQVHEQCLSLHSQL--QTLQQQDVL-EAQRLQKA----QAQFDTAL 758

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1160 AAVVEARAQASAAGILEEDLRTARSALKlknEEVESERERAQALQEQGELKVAQGKALQ----------ENLALLTQTLA 1229
Cdd:PRK10246  759 QASVFDDQQAFLAALLDEETLTQLEQLK---QNLENQRQQAQTLVTQTAQALAQHQQHRpdgldltvtvEQIQQELAQLA 835

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|..
gi 768015747 1230 EREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVD 1271
Cdd:PRK10246  836 QQLRENTTRQGEIRQQLKQDADNRQQQQALMQQIAQATQQVE 877
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1633-1855 7.47e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 7.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1633 RVKEKADALQGALEqahmTLKERHGELQDHKEQARRLE------EELAVEGRRVQALEEVLGDLRAESREQEKALLAlqq 1706
Cdd:COG4913   222 DTFEAADALVEHFD----DLERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAALRLWFAQRRLELLE--- 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1707 qcaEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAraraeaLQEALGKAHAALQGKEQHLLEQA 1786
Cdd:COG4913   295 ---AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ------LEREIERLERELEERERRRARLE 365

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768015747 1787 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQER 1855
Cdd:COG4913   366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
mukB PRK04863
chromosome partition protein MukB;
1658-2036 7.53e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 7.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1658 ELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQ----------------CAEQAQEHEVETRA 1721
Cdd:PRK04863  280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDyqaasdhlnlvqtalrQQEKIERYQADLEE 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1722 LQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEAL-------GKAHAALQG--KEQHLLEQAELS-RS 1791
Cdd:PRK04863  360 LEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALdvqqtraIQYQQAVQAleRAKQLCGLPDLTaDN 439

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1792 LEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQ-----------EDVQQLQQALAQRDEELRHQQEREQLLE 1860
Cdd:PRK04863  440 AEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiagevsrSEAWDVARELLRRLREQRHLAEQLQQLR 519

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1861 KSLAQRvqenmiqeKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQqrnnLEALphshktspmEEQSLKLD 1940
Cdd:PRK04863  520 MRLSEL--------EQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEAR----LESL---------SESVSEAR 578

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747 1941 SLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQAsVLERDSEQQRLQDELELTRRAL 2020
Cdd:PRK04863  579 ERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQ-LLERERELTVERDELAARKQAL 657

                         410
                  ....*....|....*...
gi 768015747 2021 EK--ERLHSPGATSTAEL 2036
Cdd:PRK04863  658 DEeiERLSQPGGSEDPRL 675
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 225-780 8.48e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.32  E-value: 8.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  225 EEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKEREL---LQKAREELRQQLEVLEQEAWRLRRVNV--------- 292
Cdd:PRK10246  215 PEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDELqqeASRRQQALQQALAAEEKAQPQLAALSLaqparqlrp 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  293 --ELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQT---EVTAA 367
Cdd:PRK10246  295 hwERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTWLAEHDRFRQWNNELAgwrAQFSQ 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  368 LARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVG----LNQQLLQLEEENQSVCSRMEAAEQARNALQV 443
Cdd:PRK10246  375 QTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAeqrpLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQ 454

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  444 DLAEA----EKRREALWEKNTHL---------EAQLQKAEEAGAELQA---------------------DLRDIQEEKEE 489
Cdd:PRK10246  455 EQTQRnaalNEMRQRYKEKTQQLadvkticeqEARIKDLEAQRAQLQAgqpcplcgstshpaveayqalEPGVNQSRLDA 534

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  490 IQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQglssAKELLES 569
Cdd:PRK10246  535 LEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQPWLD----AQEEHER 610

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  570 SLFEAQQQNSVievtKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAA--------RQLAQAEQEGKTA 641
Cdd:PRK10246  611 QLRLLSQRHEL----QGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASwlatrqqeAQSWQQRQNELTA 686

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  642 LEQQKAAHEKEVNQLREK-----------WEKERSWHQQ--ELAKALESLEREKMELEMRLKEQQTEME-AIQAQREEER 707
Cdd:PRK10246  687 LQNRIQQLTPLLETLPQSddlphseetvaLDNWRQVHEQclSLHSQLQTLQQQDVLEAQRLQKAQAQFDtALQASVFDDQ 766

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768015747  708 TQAESALCQ----MQLETEKERvslLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKE 780
Cdd:PRK10246  767 QAFLAALLDeetlTQLEQLKQN---LENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQIQQELAQLAQQLRE 840
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1370-1633 9.06e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 9.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1370 QQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQR-QKEHLT 1448
Cdd:pfam17380  280 HQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERiRQEERK 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1449 QDLER-RDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKL 1527
Cdd:pfam17380  360 RELERiRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRR 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  1528 ILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQR----EQEIVVLQQQLQEARE---QGELKEQSLQ 1600
Cdd:pfam17380  440 LEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRkraeEQRRKILEKELEERKQamiEEERKRKLLE 519

                          250       260       270
                   ....*....|....*....|....*....|...
gi 768015747  1601 SQLDEAQRALAQRDQELEALQQEQQQAQGQEER 1633
Cdd:pfam17380  520 KEMEERQKAIYEEERRREAEEERRKQQEMEERR 552
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 595-724 9.48e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.35  E-value: 9.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  595 VTQAKEVIQGEVrcLKLE-----LDTERSQAEQERDAAARQLAQAEQEgKTALEQQKaahekevNQLREKWEKERSWHQQ 669
Cdd:PRK00409  504 IEEAKKLIGEDK--EKLNeliasLEELERELEQKAEEAEALLKEAEKL-KEELEEKK-------EKLQEEEDKLLEEAEK 573

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 768015747  670 ELAKALESLEREKMELEMRLKEQQTEMEAiqAQREEERTQAESALCQMQLETEKE 724
Cdd:PRK00409  574 EAQQAIKEAKKEADEIIKELRQLQKGGYA--SVKAHELIEARKRLNKANEKKEKK 626
PRK12704 PRK12704
phosphodiesterase; Provisional
 821-967 9.98e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 9.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768015747  821 DDSQRLVEQEVQEKLRETQ-EYNRIQKELEREKASLTLSLMEKEQRLlvLQEADSIRqQELSALRQDMQEAQGEQKELSA 899
Cdd:PRK12704   45 EEAKKEAEAIKKEALLEAKeEIHKLRNEFEKELRERRNELQKLEKRL--LQKEENLD-RKLELLEKREEELEKKEKELEQ 121

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768015747  900 QMEllrqEVKEKEADFLAQEAQLLEELEasHIteqqlrASLWAQEAKaaqlQLRLRSTESQLEALAAE 967
Cdd:PRK12704  122 KQQ----ELEKKEEELEELIEEQLQELE--RI------SGLTAEEAK----EILLEKVEEEARHEAAV 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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