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Conserved domains on  [gi|731347755|ref|XP_010685148|]
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probable disease resistance protein At4g27220 [Beta vulgaris subsp. vulgaris]

Protein Classification

NB-LRR family disease resistance protein( domain architecture ID 11837295)

NB-LRR (nucleotide-binding-leucine rich repeat) family disease resistance protein guards the plant against pathogens via an indirect interaction with an avirulence protein contained in the plant, triggering a defense response that restricts the pathogen growth

CATH:  3.80.10.10
Gene Ontology:  GO:0006952|GO:0005515|GO:0000166
PubMed:  20483655|25825425|9545207|21459033|11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NB-ARC super family cl26397
NB-ARC domain;
68-284 3.20e-30

NB-ARC domain;


The actual alignment was detected with superfamily member pfam00931:

Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 119.79  E-value: 3.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755   68 LEKILSWLSD-DKINKIGVFGMGGCGKTTLAVHVYNRilQSDLSR---VLVWVTVGMNFDVHKLQLCISRAVGL--DLEN 141
Cdd:pfam00931   5 VEKVIGKLSEkDEPGIVGIHGMGGVGKTTLAAQIFND--FDEVEGhfdSVAWVVVSKTFTISTLQQTILQNLGLseDDWD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  142 EKDETKGAARLHDYLsKRGRYVLILDNLWEHYSFEKVGIP-----SACKVIITTRMLSICRRTGCQ-KTIKIGMLGDCEA 215
Cdd:pfam00931  83 NKEEGELARKIRRAL-LTKRFLLVLDDVWDEEDWDKIGIPlpdreNGCRVLLTTRSEEVAGRVGGPsDPHEVELLEPDEA 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 731347755  216 WQLFCS-VLEYEPLPGDDIGHIAQLVCQECAGLPLGIVHMARSLRGVNKVSEWKYSM----RQLKEVPKEHDFL 284
Cdd:pfam00931 162 WELFENkVFPKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKTVEEWKHVYdvlqSELKSNSYSLNSV 235
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
394-538 1.12e-16

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.12e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 394 LAICNSQLKEVVQALEFKEDIHAVSLMKNYITEIPFDTSpKCPKLSVLLLQHNPLKNVPSSFFlHMPSLRVLDLSNTNIQ 473
Cdd:COG4886  141 LDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEPLG-NLTNLEELDLSGNQLT 218

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 731347755 474 RLPDSTCELKNLRSLLLHCCQkLTYVPALVNLKALQMLDLGYTAIKKIPFgIERLTMLRELDLSG 538
Cdd:COG4886  219 DLPEPLANLTNLETLDLSNNQ-LTDLPELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSN 281
 
Name Accession Description Interval E-value
NB-ARC pfam00931
NB-ARC domain;
68-284 3.20e-30

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 119.79  E-value: 3.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755   68 LEKILSWLSD-DKINKIGVFGMGGCGKTTLAVHVYNRilQSDLSR---VLVWVTVGMNFDVHKLQLCISRAVGL--DLEN 141
Cdd:pfam00931   5 VEKVIGKLSEkDEPGIVGIHGMGGVGKTTLAAQIFND--FDEVEGhfdSVAWVVVSKTFTISTLQQTILQNLGLseDDWD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  142 EKDETKGAARLHDYLsKRGRYVLILDNLWEHYSFEKVGIP-----SACKVIITTRMLSICRRTGCQ-KTIKIGMLGDCEA 215
Cdd:pfam00931  83 NKEEGELARKIRRAL-LTKRFLLVLDDVWDEEDWDKIGIPlpdreNGCRVLLTTRSEEVAGRVGGPsDPHEVELLEPDEA 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 731347755  216 WQLFCS-VLEYEPLPGDDIGHIAQLVCQECAGLPLGIVHMARSLRGVNKVSEWKYSM----RQLKEVPKEHDFL 284
Cdd:pfam00931 162 WELFENkVFPKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKTVEEWKHVYdvlqSELKSNSYSLNSV 235
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
394-538 1.12e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.12e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 394 LAICNSQLKEVVQALEFKEDIHAVSLMKNYITEIPFDTSpKCPKLSVLLLQHNPLKNVPSSFFlHMPSLRVLDLSNTNIQ 473
Cdd:COG4886  141 LDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEPLG-NLTNLEELDLSGNQLT 218

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 731347755 474 RLPDSTCELKNLRSLLLHCCQkLTYVPALVNLKALQMLDLGYTAIKKIPFgIERLTMLRELDLSG 538
Cdd:COG4886  219 DLPEPLANLTNLETLDLSNNQ-LTDLPELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSN 281
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 71-549 4.56e-13

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 73.37  E-value: 4.56e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755   71 ILSWLSDDKINKIGVFGMGGCGKTTLAVHVYNRI---LQSDLSRVLVWVTVGM------NFDVHKLQLCISRAVG---LD 138
Cdd:PLN03210  198 SLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLsrqFQSSVFIDRAFISKSMeiyssaNPDDYNMKLHLQRAFLseiLD 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  139 LENEKDETKGAARlhdYLSKRGRYVLILDNLWEHYSFEKVG-----IPSACKVIITTRMLSICRRTGCQKTIKIGMLGDC 213
Cdd:PLN03210  278 KKDIKIYHLGAME---ERLKHRKVLIFIDDLDDQDVLDALAgqtqwFGSGSRIIVITKDKHFLRAHGIDHIYEVCLPSNE 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  214 EAWQLFCSVLEYEPLPGDDIGHIAQLVCQECAGLPLGIVHMARSLRGVNKvsewKYSMRQLKEVPKEHDFLVTKHLYLkl 293
Cdd:PLN03210  355 LALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDK----EDWMDMLPRLRNGLDGKIEKTLRV-- 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  294 hsSYARLANAKIKLSLLYYTlypkdCKIQREElirlwiavglIDEVSSLQAQYDQGHTI-VNELVDSSLLETSGDglFVK 372
Cdd:PLN03210  429 --SYDGLNNKKDKAIFRHIA-----CLFNGEK----------VNDIKLLLANSDLDVNIgLKNLVDKSLIHVRED--IVE 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  373 MHDVIRNMAVKITREKD---GPR-FLA----IC-----NSQLKEVVQ-ALEFKE----DIHAVSL--MKNYI-------- 424
Cdd:PLN03210  490 MHSLLQEMGKEIVRAQSnepGEReFLVdakdICdvledNTGTKKVLGiTLDIDEidelHIHENAFkgMRNLLflkfytkk 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  425 ----TEIP------FDTSPkcPKLSVLLLQHNPLKNVPSSFflHMPSLRVLDLSNTNIQRLPDSTCELKNLRSLLLHCCQ 494
Cdd:PLN03210  570 wdqkKEVRwhlpegFDYLP--PKLRLLRWDKYPLRCMPSNF--RPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 731347755  495 KLTYVPALVNLKALQMLDLG-YTAIKKIPFGIERLTMLRELDLSGLHKLKEVGCGL 549
Cdd:PLN03210  646 NLKEIPDLSMATNLETLKLSdCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGI 701
LRR_8 pfam13855
Leucine rich repeat;
436-490 1.83e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.37  E-value: 1.83e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 731347755  436 PKLSVLLLQHNPLKNVPSSFFLHMPSLRVLDLSNTNIQRL-PDSTCELKNLRSLLL 490
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDL 56
COG3903 COG3903
Predicted ATPase [General function prediction only];
85-251 4.56e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 53.87  E-value: 4.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  85 VFGMGGCGKTTLAVHVYNRILQS--------DLSRV----LVWVTVGmnfdvhklqlcisRAVGLDLENEKDetkGAARL 152
Cdd:COG3903  181 LTGPGGVGKTRLALEVAHRLADRfpdgvwfvDLAGVtdpaLVLAAVA-------------RALGVRDAPGRD---PAARL 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 153 HDYLSKRgRYVLILDNLwEHYSFEKVG-----IPSA--CKVIITTR--------------MLSICRRTgcqktikiGMLG 211
Cdd:COG3903  245 RAALADR-RLLLVLDNC-EHVVDAAAAlvrplLPAApgLRVLATSReplglpgervlplpPLAVPPPG--------AEAL 314

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 731347755 212 DCEAWQLFC----SVLEYEPLPGDDIGHIAQLvCQECAGLPLGI 251
Cdd:COG3903  315 ASEAVALFVeragAARPGFALDAAEAAAVAEI-CRRLDGLPLAI 357
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 414-591 2.62e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 46.32  E-value: 2.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 414 IHAVSLMKNYITEIPFDTSpkCPKLSVLLLQHNPLKNVPSSFFLhmPSLRVLDLSNTNIQRLPDstcelknlrslllhcc 493
Cdd:cd21340    4 ITHLYLNDKNITKIDNLSL--CKNLKVLYLYDNKITKIENLEFL--TNLTHLYLQNNQIEKIEN---------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 494 qkltyvpaLVNLKALQMLDLGYTAIKKIPfGIERLTMLRELDLS------GLHKLKEVGCgLLAMPPALK-------RIS 560
Cdd:cd21340   64 --------LENLVNLKKLYLGGNRISVVE-GLENLTNLEELHIEnqrlppGEKLTFDPRS-LAALSNSLRvlnisgnNID 133

                        170       180       190
                 ....*....|....*....|....*....|.
gi 731347755 561 CyvvggiLQELQTLRSLEILDATFKNISEYN 591
Cdd:cd21340  134 S------LEPLAPLRNLEQLDASNNQISDLE 158
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 436-545 3.11e-05

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 47.95  E-value: 3.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  436 PKLSVLLLQHNP-LKNVPSSF--FLHMPSLRVLDLsnTNIQRLPdSTCELKNLRSLLLHCCQKLTYVPALVNlkALQMLD 512
Cdd:PLN03210  778 PSLTRLFLSDIPsLVELPSSIqnLHKLEHLEIENC--INLETLP-TGINLESLESLDLSGCSRLRTFPDIST--NISDLN 852

                          90       100       110
                  ....*....|....*....|....*....|...
gi 731347755  513 LGYTAIKKIPFGIERLTMLRELDLSGLHKLKEV 545
Cdd:PLN03210  853 LSRTGIEEVPWWIEKFSNLSFLDMNGCNNLQRV 885
 
Name Accession Description Interval E-value
NB-ARC pfam00931
NB-ARC domain;
68-284 3.20e-30

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 119.79  E-value: 3.20e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755   68 LEKILSWLSD-DKINKIGVFGMGGCGKTTLAVHVYNRilQSDLSR---VLVWVTVGMNFDVHKLQLCISRAVGL--DLEN 141
Cdd:pfam00931   5 VEKVIGKLSEkDEPGIVGIHGMGGVGKTTLAAQIFND--FDEVEGhfdSVAWVVVSKTFTISTLQQTILQNLGLseDDWD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  142 EKDETKGAARLHDYLsKRGRYVLILDNLWEHYSFEKVGIP-----SACKVIITTRMLSICRRTGCQ-KTIKIGMLGDCEA 215
Cdd:pfam00931  83 NKEEGELARKIRRAL-LTKRFLLVLDDVWDEEDWDKIGIPlpdreNGCRVLLTTRSEEVAGRVGGPsDPHEVELLEPDEA 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 731347755  216 WQLFCS-VLEYEPLPGDDIGHIAQLVCQECAGLPLGIVHMARSLRGVNKVSEWKYSM----RQLKEVPKEHDFL 284
Cdd:pfam00931 162 WELFENkVFPKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLSCKKTVEEWKHVYdvlqSELKSNSYSLNSV 235
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
394-538 1.12e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.12e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 394 LAICNSQLKEVVQALEFKEDIHAVSLMKNYITEIPFDTSpKCPKLSVLLLQHNPLKNVPSSFFlHMPSLRVLDLSNTNIQ 473
Cdd:COG4886  141 LDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEPLG-NLTNLEELDLSGNQLT 218

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 731347755 474 RLPDSTCELKNLRSLLLHCCQkLTYVPALVNLKALQMLDLGYTAIKKIPFgIERLTMLRELDLSG 538
Cdd:COG4886  219 DLPEPLANLTNLETLDLSNNQ-LTDLPELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSN 281
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
416-589 7.98e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.58  E-value: 7.98e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 416 AVSLMKNYITEIPFDTSPKCPKLSVLLLQHNPlknvpssFFLHMPSLRVLDLSNTNIQRLPDSTCELKNLRSLLLHCCQk 495
Cdd:COG4886   76 LLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQ- 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 496 LTYVPA-LVNLKALQMLDLGYTAIKKIPFGIERLTMLRELDLSG--LHKLKEVgcglLAMPPALKRISCYV--VGGILQE 570
Cdd:COG4886  148 LTDLPEpLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNnqITDLPEP----LGNLTNLEELDLSGnqLTDLPEP 223

                        170
                 ....*....|....*....
gi 731347755 571 LQTLRSLEILDATFKNISE 589
Cdd:COG4886  224 LANLTNLETLDLSNNQLTD 242
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 71-549 4.56e-13

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 73.37  E-value: 4.56e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755   71 ILSWLSDDKINKIGVFGMGGCGKTTLAVHVYNRI---LQSDLSRVLVWVTVGM------NFDVHKLQLCISRAVG---LD 138
Cdd:PLN03210  198 SLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLsrqFQSSVFIDRAFISKSMeiyssaNPDDYNMKLHLQRAFLseiLD 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  139 LENEKDETKGAARlhdYLSKRGRYVLILDNLWEHYSFEKVG-----IPSACKVIITTRMLSICRRTGCQKTIKIGMLGDC 213
Cdd:PLN03210  278 KKDIKIYHLGAME---ERLKHRKVLIFIDDLDDQDVLDALAgqtqwFGSGSRIIVITKDKHFLRAHGIDHIYEVCLPSNE 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  214 EAWQLFCSVLEYEPLPGDDIGHIAQLVCQECAGLPLGIVHMARSLRGVNKvsewKYSMRQLKEVPKEHDFLVTKHLYLkl 293
Cdd:PLN03210  355 LALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDK----EDWMDMLPRLRNGLDGKIEKTLRV-- 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  294 hsSYARLANAKIKLSLLYYTlypkdCKIQREElirlwiavglIDEVSSLQAQYDQGHTI-VNELVDSSLLETSGDglFVK 372
Cdd:PLN03210  429 --SYDGLNNKKDKAIFRHIA-----CLFNGEK----------VNDIKLLLANSDLDVNIgLKNLVDKSLIHVRED--IVE 489

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  373 MHDVIRNMAVKITREKD---GPR-FLA----IC-----NSQLKEVVQ-ALEFKE----DIHAVSL--MKNYI-------- 424
Cdd:PLN03210  490 MHSLLQEMGKEIVRAQSnepGEReFLVdakdICdvledNTGTKKVLGiTLDIDEidelHIHENAFkgMRNLLflkfytkk 569

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  425 ----TEIP------FDTSPkcPKLSVLLLQHNPLKNVPSSFflHMPSLRVLDLSNTNIQRLPDSTCELKNLRSLLLHCCQ 494
Cdd:PLN03210  570 wdqkKEVRwhlpegFDYLP--PKLRLLRWDKYPLRCMPSNF--RPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSK 645

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 731347755  495 KLTYVPALVNLKALQMLDLG-YTAIKKIPFGIERLTMLRELDLSGLHKLKEVGCGL 549
Cdd:PLN03210  646 NLKEIPDLSMATNLETLKLSdCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGI 701
LRR_8 pfam13855
Leucine rich repeat;
436-490 1.83e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.37  E-value: 1.83e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 731347755  436 PKLSVLLLQHNPLKNVPSSFFLHMPSLRVLDLSNTNIQRL-PDSTCELKNLRSLLL 490
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDL 56
COG3903 COG3903
Predicted ATPase [General function prediction only];
85-251 4.56e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 53.87  E-value: 4.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  85 VFGMGGCGKTTLAVHVYNRILQS--------DLSRV----LVWVTVGmnfdvhklqlcisRAVGLDLENEKDetkGAARL 152
Cdd:COG3903  181 LTGPGGVGKTRLALEVAHRLADRfpdgvwfvDLAGVtdpaLVLAAVA-------------RALGVRDAPGRD---PAARL 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 153 HDYLSKRgRYVLILDNLwEHYSFEKVG-----IPSA--CKVIITTR--------------MLSICRRTgcqktikiGMLG 211
Cdd:COG3903  245 RAALADR-RLLLVLDNC-EHVVDAAAAlvrplLPAApgLRVLATSReplglpgervlplpPLAVPPPG--------AEAL 314

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 731347755 212 DCEAWQLFC----SVLEYEPLPGDDIGHIAQLvCQECAGLPLGI 251
Cdd:COG3903  315 ASEAVALFVeragAARPGFALDAAEAAAVAEI-CRRLDGLPLAI 357
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
462-589 3.70e-06

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 50.32  E-value: 3.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 462 LRVLDLSNTNIQRLPDSTCELKNLRSLLLHCCQKLTyvpalvNLKALQMLDLGYTAIKKIPFGIERLTMLRELDLSGlHK 541
Cdd:COG4886   75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELS------NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSN-NQ 147

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 731347755 542 LKEVGCGLLAMpPALKRISCYV--VGGILQELQTLRSLEILDATFKNISE 589
Cdd:COG4886  148 LTDLPEPLGNL-TNLKSLDLSNnqLTDLPEELGNLTNLKELDLSNNQITD 196
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 414-591 2.62e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 46.32  E-value: 2.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 414 IHAVSLMKNYITEIPFDTSpkCPKLSVLLLQHNPLKNVPSSFFLhmPSLRVLDLSNTNIQRLPDstcelknlrslllhcc 493
Cdd:cd21340    4 ITHLYLNDKNITKIDNLSL--CKNLKVLYLYDNKITKIENLEFL--TNLTHLYLQNNQIEKIEN---------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 494 qkltyvpaLVNLKALQMLDLGYTAIKKIPfGIERLTMLRELDLS------GLHKLKEVGCgLLAMPPALK-------RIS 560
Cdd:cd21340   64 --------LENLVNLKKLYLGGNRISVVE-GLENLTNLEELHIEnqrlppGEKLTFDPRS-LAALSNSLRvlnisgnNID 133

                        170       180       190
                 ....*....|....*....|....*....|.
gi 731347755 561 CyvvggiLQELQTLRSLEILDATFKNISEYN 591
Cdd:cd21340  134 S------LEPLAPLRNLEQLDASNNQISDLE 158
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 436-545 3.11e-05

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 47.95  E-value: 3.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755  436 PKLSVLLLQHNP-LKNVPSSF--FLHMPSLRVLDLsnTNIQRLPdSTCELKNLRSLLLHCCQKLTYVPALVNlkALQMLD 512
Cdd:PLN03210  778 PSLTRLFLSDIPsLVELPSSIqnLHKLEHLEIENC--INLETLP-TGINLESLESLDLSGCSRLRTFPDIST--NISDLN 852

                          90       100       110
                  ....*....|....*....|....*....|...
gi 731347755  513 LGYTAIKKIPFGIERLTMLRELDLSGLHKLKEV 545
Cdd:PLN03210  853 LSRTGIEEVPWWIEKFSNLSFLDMNGCNNLQRV 885
LRR_8 pfam13855
Leucine rich repeat;
417-472 6.83e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.66  E-value: 6.83e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 731347755  417 VSLMKNYITEIPFDTSPKCPKLSVLLLQHNPLKNVPSSFFLHMPSLRVLDLSNTNI 472
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 426-538 6.29e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.22  E-value: 6.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755 426 EIPFDTSpKCPKLSVLLLQHNPLKNVPSSFFLHMPSLRVLDLSNTNIQ-RLPDSTCELKNLRSLLLHCCQKLTYVPALVN 504
Cdd:PLN00113 395 EIPKSLG-ACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFG 473

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 731347755 505 LKALQMLDLGYTAIKK-IPFGIERLTMLRELDLSG 538
Cdd:PLN00113 474 SKRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSE 508
AAA_22 pfam13401
AAA domain;
85-168 6.50e-03

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 37.71  E-value: 6.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 731347755   85 VFGMGGCGKTTLAVHVYNRILQSDLSRVLVWVTVGMNFDvhklQLC--ISRAVGLDLENEKDETKGAARLHDYLSKRGRY 162
Cdd:pfam13401  10 LTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSPK----DLLraLLRALGLPLSGRLSKEELLAALQQLLLALAVA 85


                  ....*..
gi 731347755  163 -VLILDN 168
Cdd:pfam13401  86 vVLIIDE 92
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 460-504 7.84e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.91  E-value: 7.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 731347755  460 PSLRVLDLSNTNIQRLPDSTCeLKNLRSLLLHCCQKLTYVPALVN 504
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPPLAK-LPNLETLDLSGNNKITDLSDLAN 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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