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Conserved domains on  [gi|1631911295|ref|XP_010174778|]
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LOW QUALITY PROTEIN: hyaluronidase-2-like, partial [Antrostomus carolinensis]

Protein Classification

hyaluronidase( domain architecture ID 10483192)

hyaluronidase catalyzes the degradation of hyaluronic acid

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Glyco_hydro_56 pfam01630
Hyaluronidase;
1-332 6.62e-157

Hyaluronidase;


:

Pssm-ID: 460272  Cd Length: 332  Bit Score: 442.33  E-value: 6.62e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295   1 TRRPFLVAWNVPTQDCKPRFQVPLDLSLFDLQASPNEGFVGQNLTIFYKERLGLYPYYTAQGVAVNaSGAPAAAHLDHQG 80
Cdd:pfam01630   4 PNRPFLVVWNAPTERCKPRFNVPLDLSLFGIVANPNEGFRGQNITIFYKDRLGLYPYYDEDGGPVN-GGIPQNGSLTAHL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295  81 GEQASGV*V*VGRPAVHGehpacgqelppqaaLGLlplp*llqp*lqqeqgkLHWAN---------------RRQ----- 140
Cdd:pfam01630  83 EKAKEDIEKYIPSPDFSG--------------LAV-----------------IDWEEwrplwirnwgskdiyRNKsielv 131
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295 141 ----PTWTIKEVNKQAVYEFESAARQFMVSTLRVAKSFRPKQLWGFYLFPDCYNHDYSKNkeSYTGQCPDVEKTRNDQLA 216
Cdd:pfam01630 132 rqqhPDWSPEEVEKLAKQEFEKAARAFMEETLRLGKSLRPNGLWGFYLFPDCYNYDYKKP--NYTGRCPDVEKKRNDQLL 209
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295 217 WLWRESMALYPSIYLDLLLASTPNSRKFVRARVMEAIRISQQHHDGYSLPVFVYTRPTYIRKLDVLSQPDLISTIGESAA 296
Cdd:pfam01630 210 WLWNESTALYPSIYLPKKLKSSPKALLFVRNRVQEALRVASVAKADYPLPVFVYTRPVYTDSLEFLSEEDLVNTIGESAA 289
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1631911295 297 LGAAGAIFWGDADYTKNRDSCQIIKNYLEEDLGRYI 332
Cdd:pfam01630 290 LGAAGVVLWGDSNYSNSKESCLALKDYLKTTLGPYI 325
 
Name Accession Description Interval E-value
Glyco_hydro_56 pfam01630
Hyaluronidase;
1-332 6.62e-157

Hyaluronidase;


Pssm-ID: 460272  Cd Length: 332  Bit Score: 442.33  E-value: 6.62e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295   1 TRRPFLVAWNVPTQDCKPRFQVPLDLSLFDLQASPNEGFVGQNLTIFYKERLGLYPYYTAQGVAVNaSGAPAAAHLDHQG 80
Cdd:pfam01630   4 PNRPFLVVWNAPTERCKPRFNVPLDLSLFGIVANPNEGFRGQNITIFYKDRLGLYPYYDEDGGPVN-GGIPQNGSLTAHL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295  81 GEQASGV*V*VGRPAVHGehpacgqelppqaaLGLlplp*llqp*lqqeqgkLHWAN---------------RRQ----- 140
Cdd:pfam01630  83 EKAKEDIEKYIPSPDFSG--------------LAV-----------------IDWEEwrplwirnwgskdiyRNKsielv 131
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295 141 ----PTWTIKEVNKQAVYEFESAARQFMVSTLRVAKSFRPKQLWGFYLFPDCYNHDYSKNkeSYTGQCPDVEKTRNDQLA 216
Cdd:pfam01630 132 rqqhPDWSPEEVEKLAKQEFEKAARAFMEETLRLGKSLRPNGLWGFYLFPDCYNYDYKKP--NYTGRCPDVEKKRNDQLL 209
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295 217 WLWRESMALYPSIYLDLLLASTPNSRKFVRARVMEAIRISQQHHDGYSLPVFVYTRPTYIRKLDVLSQPDLISTIGESAA 296
Cdd:pfam01630 210 WLWNESTALYPSIYLPKKLKSSPKALLFVRNRVQEALRVASVAKADYPLPVFVYTRPVYTDSLEFLSEEDLVNTIGESAA 289
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1631911295 297 LGAAGAIFWGDADYTKNRDSCQIIKNYLEEDLGRYI 332
Cdd:pfam01630 290 LGAAGVVLWGDSNYSNSKESCLALKDYLKTTLGPYI 325
 
Name Accession Description Interval E-value
Glyco_hydro_56 pfam01630
Hyaluronidase;
1-332 6.62e-157

Hyaluronidase;


Pssm-ID: 460272  Cd Length: 332  Bit Score: 442.33  E-value: 6.62e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295   1 TRRPFLVAWNVPTQDCKPRFQVPLDLSLFDLQASPNEGFVGQNLTIFYKERLGLYPYYTAQGVAVNaSGAPAAAHLDHQG 80
Cdd:pfam01630   4 PNRPFLVVWNAPTERCKPRFNVPLDLSLFGIVANPNEGFRGQNITIFYKDRLGLYPYYDEDGGPVN-GGIPQNGSLTAHL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295  81 GEQASGV*V*VGRPAVHGehpacgqelppqaaLGLlplp*llqp*lqqeqgkLHWAN---------------RRQ----- 140
Cdd:pfam01630  83 EKAKEDIEKYIPSPDFSG--------------LAV-----------------IDWEEwrplwirnwgskdiyRNKsielv 131
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295 141 ----PTWTIKEVNKQAVYEFESAARQFMVSTLRVAKSFRPKQLWGFYLFPDCYNHDYSKNkeSYTGQCPDVEKTRNDQLA 216
Cdd:pfam01630 132 rqqhPDWSPEEVEKLAKQEFEKAARAFMEETLRLGKSLRPNGLWGFYLFPDCYNYDYKKP--NYTGRCPDVEKKRNDQLL 209
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631911295 217 WLWRESMALYPSIYLDLLLASTPNSRKFVRARVMEAIRISQQHHDGYSLPVFVYTRPTYIRKLDVLSQPDLISTIGESAA 296
Cdd:pfam01630 210 WLWNESTALYPSIYLPKKLKSSPKALLFVRNRVQEALRVASVAKADYPLPVFVYTRPVYTDSLEFLSEEDLVNTIGESAA 289
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1631911295 297 LGAAGAIFWGDADYTKNRDSCQIIKNYLEEDLGRYI 332
Cdd:pfam01630 290 LGAAGVVLWGDSNYSNSKESCLALKDYLKTTLGPYI 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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