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Conserved domains on  [gi|701332187|ref|XP_009978635|]
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PREDICTED: ubiquinone biosynthesis monooxygenase COQ6, partial [Tauraco erythrolophus]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 5-414 0e+00

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 563.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187    5 LGHDIHFHDKKIALLEAGPRKE-----YDRMPDSYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAM 79
Cdd:TIGR01989  19 LGNNPLTKDLKVLLLDAVDNPKlksrnYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDGCSLAL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187   80 IVFEKDD-LDDMGYIVENDVIMSALTKQLDAV-ADRVEVFYESRAVGYTWPlPSHSSDTSPWVQIQLADGRRLQTKLLIG 157
Cdd:TIGR01989  99 IRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIP-SKYPNDNSNWVHITLSDGQVLYTKLLIG 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  158 ADGHNSVVRKKAEIKNIEHQYDQSAVVATLHLSEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDE 237
Cdd:TIGR01989 178 ADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPP 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  238 ESFVDSINSAF---WSNVNHSDFIDTAGAMFRSAISLLKPSGTAARQLPPSVARVDPESRAMFPLGMGHATEYVQHRVAL 314
Cdd:TIGR01989 258 EDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYVTKRVAL 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  315 IGDAAHRVHPLAGQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVL 394
Cdd:TIGR01989 338 VGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVA 417

                         410       420
                  ....*....|....*....|
gi 701332187  395 LRTWGLQATNALPPVKEQIM 414
Cdd:TIGR01989 418 LRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 5-414 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 563.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187    5 LGHDIHFHDKKIALLEAGPRKE-----YDRMPDSYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAM 79
Cdd:TIGR01989  19 LGNNPLTKDLKVLLLDAVDNPKlksrnYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDGCSLAL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187   80 IVFEKDD-LDDMGYIVENDVIMSALTKQLDAV-ADRVEVFYESRAVGYTWPlPSHSSDTSPWVQIQLADGRRLQTKLLIG 157
Cdd:TIGR01989  99 IRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIP-SKYPNDNSNWVHITLSDGQVLYTKLLIG 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  158 ADGHNSVVRKKAEIKNIEHQYDQSAVVATLHLSEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDE 237
Cdd:TIGR01989 178 ADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPP 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  238 ESFVDSINSAF---WSNVNHSDFIDTAGAMFRSAISLLKPSGTAARQLPPSVARVDPESRAMFPLGMGHATEYVQHRVAL 314
Cdd:TIGR01989 258 EDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYVTKRVAL 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  315 IGDAAHRVHPLAGQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVL 394
Cdd:TIGR01989 338 VGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVA 417

                         410       420
                  ....*....|....*....|
gi 701332187  395 LRTWGLQATNALPPVKEQIM 414
Cdd:TIGR01989 418 LRTFGLNLTNYIGPLKNFIM 437
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 13-417 4.74e-77

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 244.68  E-value: 4.74e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  13 DKKIALLEAG-PRKEYDRMPDsysNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAMIVFEKDDL--DD 89
Cdd:PRK08850  27 DLRIAVIEGQlPEEALNELPD---VRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPD 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  90 MGYIVENDVIMSALtkqLDAV--ADRVEVFYESRAVGYTwplpshSSDTSPWvqIQLADGRRLQTKLLIGADGHNSVVRK 167
Cdd:PRK08850 104 LGHIVENRVIQLAL---LEQVqkQDNVTLLMPARCQSIA------VGESEAW--LTLDNGQALTAKLVVGADGANSWLRR 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 168 KAEIKNIEHQYDQSAVVATLHLSEaTDNNVAWQRFLPTGPIALLPLSDT-ASSLVWSTSHEHASELLSMDEESFVDSINS 246
Cdd:PRK08850 173 QMDIPLTHWDYGHSALVANVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTA 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 247 AFwsnvnhsdfidtagamfRSAISLLKPSGTaarqlppsvarvdpesRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLA 326
Cdd:PRK08850 252 EF-----------------DNRLGLCEVVGE----------------RQAFPLKMRYARDFVRERVALVGDAAHTIHPLA 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 327 GQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNAL 406
Cdd:PRK08850 299 GQGVNLGLLDAASLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQL 378

                        410
                 ....*....|.
gi 701332187 407 PPVKEQIMAFA 417
Cdd:PRK08850 379 PGAKDEIMKRA 389
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 15-410 7.12e-44

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 155.48  E-value: 7.12e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAGPRKEYDRmpdsysnRVSSVSPGSATLLSSFGAWDHVCSLRLkPFRRMQVWDACSEAMI--VFEKDDLDDMGY 92
Cdd:COG0654   28 RVTVVERAPPPRPDG-------RGIALSPRSLELLRRLGLWDRLLARGA-PIRGIRVRDGSDGRVLarFDAAETGLPAGL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  93 IVENDVIMSALTKQLDAvaDRVEVFYESRAVGYTWplpshSSDTspwVQIQLADGRRLQTKLLIGADGHNSVVRKKAEIK 172
Cdd:COG0654  100 VVPRADLERALLEAARA--LGVELRFGTEVTGLEQ-----DADG---VTVTLADGRTLRADLVVGADGARSAVRRLLGIG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 173 NIEHQYDQSAVVATLHlseatdnnVAWQRFLptgpiallplsdtasslvwstshehasellsmdeesfvdsinsafwsnv 252
Cdd:COG0654  170 FTGRDYPQRALWAGVR--------TELRARL------------------------------------------------- 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 253 nhsdfidtagamfrsaisllkpsgtaaRQLPPSVARV-DPESRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVN 331
Cdd:COG0654  193 ---------------------------AAAGPRLGELlELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGAN 245

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 701332187 332 LGFGDIACLAHHLsAAAFNGSDLGSLkhLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVK 410
Cdd:COG0654  246 LALRDAAALAWKL-AAALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 147-370 5.51e-10

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 60.42  E-value: 5.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  147 GRRLQTKLLIGADGHNSVVRKKAEIKNIEHQYDQSAVVATLHLS------EATDNNVAWQRFLPTGPIALLPLSDTASS- 219
Cdd:pfam01494 145 EYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWRSAGREr 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  220 ----LVWSTSHEHASELLSMDEesfvdsinsafwsnvnhsdfidtagamfrsaisllkpsgtAARQLPPSVA--RVDPES 293
Cdd:pfam01494 225 yyvqVPWDEEVEERPEEFTDEE----------------------------------------LKQRLRSIVGidLALVEI 264

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 701332187  294 RAMFPLGMGH--ATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLsAAAFNGSDLGSLkhLLKFETERQRH 370
Cdd:pfam01494 265 LWKSIWGVASrvATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKL-AAVLRGQAGESL--LDTYSAERLPV 340
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 5-414 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 563.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187    5 LGHDIHFHDKKIALLEAGPRKE-----YDRMPDSYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAM 79
Cdd:TIGR01989  19 LGNNPLTKDLKVLLLDAVDNPKlksrnYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDGCSLAL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187   80 IVFEKDD-LDDMGYIVENDVIMSALTKQLDAV-ADRVEVFYESRAVGYTWPlPSHSSDTSPWVQIQLADGRRLQTKLLIG 157
Cdd:TIGR01989  99 IRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIP-SKYPNDNSNWVHITLSDGQVLYTKLLIG 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  158 ADGHNSVVRKKAEIKNIEHQYDQSAVVATLHLSEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDE 237
Cdd:TIGR01989 178 ADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPP 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  238 ESFVDSINSAF---WSNVNHSDFIDTAGAMFRSAISLLKPSGTAARQLPPSVARVDPESRAMFPLGMGHATEYVQHRVAL 314
Cdd:TIGR01989 258 EDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYVTKRVAL 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  315 IGDAAHRVHPLAGQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVL 394
Cdd:TIGR01989 338 VGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVA 417

                         410       420
                  ....*....|....*....|
gi 701332187  395 LRTWGLQATNALPPVKEQIM 414
Cdd:TIGR01989 418 LRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 14-418 2.56e-143

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 413.52  E-value: 2.56e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187   14 KKIALLEAGPRKEYDrmPDSYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAMIVFEKDD--LDDMG 91
Cdd:TIGR01988  23 LKVALIEATPLPAPA--DPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDGGSFGALRFDADEigLEALG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187   92 YIVENDVIMSALTKQLDAvADRVEVFYESRAVGYTWplpshssdTSPWVQIQLADGRRLQTKLLIGADGHNSVVRKKAEI 171
Cdd:TIGR01988 101 YVVENRVLQQALWERLQE-LPNVTLLCPARVVELPR--------HSDHVELTLDDGQQLRARLLVGADGANSKVRQLAGI 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  172 KNIEHQYDQSAVVATLHLSEATdNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSINSAFWSN 251
Cdd:TIGR01988 172 PTTGWDYGQSAVVANVKHERPH-QGTAWERFTPTGPLALLPLPDNRSSLVWTLPPEEAERLLALSDEEFLAELQRAFGSR 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  252 vnhsdfidtAGAMfrsaisllkpsgtaarqlppsvarVDPESRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVN 331
Cdd:TIGR01988 251 ---------LGAI------------------------TLVGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLN 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  332 LGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVKE 411
Cdd:TIGR01988 298 LGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKN 377


                  ....*..
gi 701332187  412 QIMAFAS 418
Cdd:TIGR01988 378 FIARYAM 384
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 13-417 4.74e-77

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 244.68  E-value: 4.74e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  13 DKKIALLEAG-PRKEYDRMPDsysNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAMIVFEKDDL--DD 89
Cdd:PRK08850  27 DLRIAVIEGQlPEEALNELPD---VRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPD 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  90 MGYIVENDVIMSALtkqLDAV--ADRVEVFYESRAVGYTwplpshSSDTSPWvqIQLADGRRLQTKLLIGADGHNSVVRK 167
Cdd:PRK08850 104 LGHIVENRVIQLAL---LEQVqkQDNVTLLMPARCQSIA------VGESEAW--LTLDNGQALTAKLVVGADGANSWLRR 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 168 KAEIKNIEHQYDQSAVVATLHLSEaTDNNVAWQRFLPTGPIALLPLSDT-ASSLVWSTSHEHASELLSMDEESFVDSINS 246
Cdd:PRK08850 173 QMDIPLTHWDYGHSALVANVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTA 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 247 AFwsnvnhsdfidtagamfRSAISLLKPSGTaarqlppsvarvdpesRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLA 326
Cdd:PRK08850 252 EF-----------------DNRLGLCEVVGE----------------RQAFPLKMRYARDFVRERVALVGDAAHTIHPLA 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 327 GQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNAL 406
Cdd:PRK08850 299 GQGVNLGLLDAASLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQL 378

                        410
                 ....*....|.
gi 701332187 407 PPVKEQIMAFA 417
Cdd:PRK08850 379 PGAKDEIMKRA 389
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
15-418 3.12e-74

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 236.77  E-value: 3.12e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAGPRKEYDrmPDSYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVW-DAcsEAMIVFE--KDDLDDMG 91
Cdd:PRK07608  30 RVALLAPRAPPRPA--DDAWDSRVYAISPSSQAFLERLGVWQALDAARLAPVYDMRVFgDA--HARLHFSayQAGVPQLA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  92 YIVENDVIMSALTKQLdAVADRVEVFyESRAVGYTWplpSHSSdtspwVQIQLADGRRLQTKLLIGADGHNSVVRKKAEI 171
Cdd:PRK07608 106 WIVESSLIERALWAAL-RFQPNLTWF-PARAQGLEV---DPDA-----ATLTLADGQVLRADLVVGADGAHSWVRSQAGI 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 172 KNIEHQYDQSAVVATLhLSEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSinsafwsn 251
Cdd:PRK07608 176 KAERRPYRQTGVVANF-KAERPHRGTAYQWFRDDGILALLPLPDGHVSMVWSARTAHADELLALSPEALAAR-------- 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 252 vnhsdfIDTAGAMFRSAISLLKPsgtaarqlppsvarvdpesRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVN 331
Cdd:PRK07608 247 ------VERASGGRLGRLECVTP-------------------AAGFPLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMN 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 332 LGFGDIACLAHHLsAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVKE 411
Cdd:PRK07608 302 LGLRDVAALADVL-AGREPFRDLGDLRLLRRYERARREDILALQVATDGLQRLFALPGPLARWLRNAGMALVGALPLVKR 380


                 ....*..
gi 701332187 412 QIMAFAS 418
Cdd:PRK07608 381 WLVRHAL 387
PRK07364 PRK07364
FAD-dependent hydroxylase;
15-410 1.60e-71

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 230.68  E-value: 1.60e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAGPRKEYDRMPDSYSnrvssVSPGSATLLSSFGAWDHVcSLRLKPFRRMQVWDACSEAMIVFEKDDL--DDMGY 92
Cdd:PRK07364  43 RIALIEAQPAEAAAAKGQAYA-----LSLLSARIFEGIGVWEKI-LPQIGKFRQIRLSDADYPGVVKFQPTDLgtEALGY 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  93 IVENDVIMSALTKQLDAvADRVEVFYESRAVGYTWplpsHSSDTSpwVQIQLADGRR-LQTKLLIGADGHNSVVRKKAEI 171
Cdd:PRK07364 117 VGEHQVLLEALQEFLQS-CPNITWLCPAEVVSVEY----QQDAAT--VTLEIEGKQQtLQSKLVVAADGARSPIRQAAGI 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 172 KNIEHQYDQSAVVATLHLsEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSINSAFwsn 251
Cdd:PRK07364 190 KTKGWKYWQSCVTATVKH-EAPHNDIAYERFWPSGPFAILPLPGNRCQIVWTAPHAQAKALLALPEAEFLAELQQRY--- 265

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 252 vnhsdfidtAGAMFRsaISLLKPsgtaarqlppsvarvdpesRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVN 331
Cdd:PRK07364 266 ---------GDQLGK--LELLGD-------------------RFLFPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLN 315

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 701332187 332 LGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVK 410
Cdd:PRK07364 316 LGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLK 394
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 16-410 2.28e-69

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 224.71  E-value: 2.28e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  16 IALLEAGPRKEYDRMPDS-YSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAMIVFEKDDL--DDMGY 92
Cdd:PRK05714  28 VLLLDGGPLSVKPFDPQApFEPRVSALSAASQRILERLGAWDGIAARRASPYSEMQVWDGSGTGQIHFSAASVhaEVLGH 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  93 IVENDVIMSALTKQLDA------VADRVEvfyESRAVGYTWplpshssdtspwvQIQLADGRRLQTKLLIGADGHNSVVR 166
Cdd:PRK05714 108 IVENRVVQDALLERLHDsdigllANARLE---QMRRSGDDW-------------LLTLADGRQLRAPLVVAADGANSAVR 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 167 KKAEIKNIEHQYDQSAVVATLHLSEAtDNNVAWQRFLPTGPIALLPLSDTAS----SLVWSTSHEHASELLSMDEESFVD 242
Cdd:PRK05714 172 RLAGCATREWDYLHHAIVTSVRCSEP-HRATAWQRFTDDGPLAFLPLERDGDehwcSIVWSTTPEEAERLMALDDDAFCA 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 243 SINSAFWSNVNHsdfidtagamfrsaisllkpsgtaarqlppsVARVDPesRAMFPLGMGHATEYVQHRVALIGDAAHRV 322
Cdd:PRK05714 251 ALERAFEGRLGE-------------------------------VLSADP--RLCVPLRQRHAKRYVEPGLALIGDAAHTI 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 323 HPLAGQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQA 402
Cdd:PRK05714 298 HPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKL 377


                 ....*...
gi 701332187 403 TNALPPVK 410
Cdd:PRK05714 378 VDQMPEAK 385
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 15-413 1.58e-67

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 219.11  E-value: 1.58e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187   15 KIALLEAgprKEYDRMPDSYSNRVSSVSPGSATLLSSFGAWDHVCSlRLKPFRRMQVWDACSEAMIVFEKDDLDD--MGY 92
Cdd:TIGR01984  25 KIALIEA---NSPSAAQPGFDARSLALSYGSKQILEKLGLWPKLAP-FATPILDIHVSDQGHFGATHLRASEFGLpaLGY 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187   93 IVENDVIMSALTKQLDAvADRVEVFYESRAVGYTwPLPSHssdtspwVQIQLADGRRLQTKLLIGADGHNSVVRKKAEIK 172
Cdd:TIGR01984 101 VVELADLGQALLSRLAL-LTNIQLYCPARYKEII-RNQDY-------VRVTLDNGQQLRAKLLIAADGANSKVRELLSIP 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  173 NIEHQYDQSAVVATLHLSEAtDNNVAWQRFLPTGPIALLPLSD-TASSLVWSTSHEHASELLSMDEESFVDSINSAF-WS 250
Cdd:TIGR01984 172 TEEHDYNQTALIANIRHEQP-HQGCAFERFTPHGPLALLPLKDnYRSSLVWCLPSKQADTIANLPDAEFLAELQQAFgWR 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  251 nvnhsdfidtAGAMfrsaisllkpsgtaarqlppsvarVDPESRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGV 330
Cdd:TIGR01984 251 ----------LGKI------------------------TQVGERKTYPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGF 296

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  331 NLGFGDIACLAHHLSAAAfngSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVK 410
Cdd:TIGR01984 297 NLGLRDVETLAEVLIDAR---IDLGTYALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLK 373


                  ...
gi 701332187  411 EQI 413
Cdd:TIGR01984 374 KRL 376
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 15-417 1.58e-65

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 214.46  E-value: 1.58e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAGPRKEYDrmPDSYSN-RVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSeAMIVFEKDDLD--DMG 91
Cdd:PRK08020  30 SVAVLEHAAPAPFD--ADSQPDvRISAISAASVALLKGLGVWDAVQAMRSHPYRRLETWEWET-AHVVFDAAELKlpELG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  92 YIVENDVIMSALTKQLDAvADRVEVFYESRavgytwpLPSHSSDTSPWvQIQLADGRRLQTKLLIGADGHNSVVRKKAEI 171
Cdd:PRK08020 107 YMVENRVLQLALWQALEA-HPNVTLRCPAS-------LQALQRDDDGW-ELTLADGEEIQAKLVIGADGANSQVRQMAGI 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 172 KNIEHQYDQSAVVATLHlSEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSINSAFwsn 251
Cdd:PRK08020 178 GVHGWQYRQSCMLISVK-CENPPGDSTWQQFTPSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHF--- 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 252 vnhsdfidtagamfrsaisllkpsgtaarqlPPSVARVDPESRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVN 331
Cdd:PRK08020 254 -------------------------------PARLGAVTPVAAGAFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVN 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 332 LGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVKE 411
Cdd:PRK08020 303 LGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKR 382


                 ....*.
gi 701332187 412 QIMAFA 417
Cdd:PRK08020 383 QALKYA 388
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
31-409 3.28e-65

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 213.57  E-value: 3.28e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  31 PDSYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAMIVFEKDDL--DDMGYIVENDVIMSALTKQLD 108
Cdd:PRK08773  45 ADQPDLRVYAFAADNAALLDRLGVWPAVRAARAQPYRRMRVWDAGGGGELGFDADTLgrEQLGWIVENDLLVDRLWAALH 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 109 AVAdrVEVFYESRAVGYTwplPSHSSdtspwVQIQLADGRRLQTKLLIGADGHNSVVRKKAEIKNIEHQYDQSAVVA--- 185
Cdd:PRK08773 125 AAG--VQLHCPARVVALE---QDADR-----VRLRLDDGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAfvd 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 186 TLHLSEATdnnvAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSINSAFWSNVNHsdfidtagamf 265
Cdd:PRK08773 195 TEHPHQAT----AWQRFLPTGPLALLPFADGRSSIVWTLPDAEAERVLALDEAAFSRELTQAFAARLGE----------- 259

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 266 rsaISLLKPsgtaarqlppsvarvdpesRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLS 345
Cdd:PRK08773 260 ---VRVASP-------------------RTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVR 317

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 701332187 346 AAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPV 409
Cdd:PRK08773 318 QAHARRADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPL 381
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
13-411 8.11e-60

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 199.82  E-value: 8.11e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  13 DKKIALLEAGPRKEYDRMPdsysnRVSSVSPGSATLLSSFGAWDHVCSlRLKPFRRMQVWDACSE-----AMIVFEKD-- 85
Cdd:PRK07333  26 HLPVTVVDAAPAGAWSRDP-----RASAIAAAARRMLEALGVWDEIAP-EAQPITDMVITDSRTSdpvrpVFLTFEGEve 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  86 DLDDMGYIVENDVIMSALTKQLDAVAdrVEVFYESRAVGYtwplpsHSSDTSpwVQIQLADGRRLQTKLLIGADGHNSVV 165
Cdd:PRK07333 100 PGEPFAHMVENRVLINALRKRAEALG--IDLREATSVTDF------ETRDEG--VTVTLSDGSVLEARLLVAADGARSKL 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 166 RKKAEIKNIEHQYDQSAVVATL-HlsEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSI 244
Cdd:PRK07333 170 RELAGIKTVGWDYGQSGIVCTVeH--ERPHGGRAEEHFLPAGPFAILPLKGNRSSLVWTERTADAERLVALDDLVFEAEL 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 245 NSAFWSNVNHsdfidtagamfrsaislLKPSGtaarqlppsvarvdpESRAmFPLGMGHATEYVQHRVALIGDAAHRVHP 324
Cdd:PRK07333 248 EQRFGHRLGE-----------------LKVLG---------------KRRA-FPLGLTLARSFVAPRFALVGDAAHGIHP 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 325 LAGQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATN 404
Cdd:PRK07333 295 IAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVD 374


                 ....*..
gi 701332187 405 ALPPVKE 411
Cdd:PRK07333 375 RLPKLKS 381
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 14-417 6.51e-58

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 194.22  E-value: 6.51e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  14 KKIALLEAGPRKEYDRMPDsYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDAcSEAMIVFEKD--DLDDMG 91
Cdd:PRK08849  27 RSVAVIEGGEPKAFEPSQP-MDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKRLETWEH-PECRTRFHSDelNLDQLG 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  92 YIVENDVIMSALTKQLDAVaDRVEVFYESRAvgytwplpSHSSDTSPWVQIQLADGRRLQTKLLIGADGHNSVVRKKAEI 171
Cdd:PRK08849 105 YIVENRLIQLGLWQQFAQY-PNLTLMCPEKL--------ADLEFSAEGNRVTLESGAEIEAKWVIGADGANSQVRQLAGI 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 172 KNIEHQYDQSAVVATLHlSEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESfvdsinsafwsn 251
Cdd:PRK08849 176 GITAWDYRQHCMLINVE-TEQPQQDITWQQFTPSGPRSFLPLCGNQGSLVWYDSPKRIKQLSAMNPEQ------------ 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 252 vnhsdfidtagamFRSAIsllkpsgtaARQLPPSVARVDPESRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVN 331
Cdd:PRK08849 243 -------------LRSEI---------LRHFPAELGEIKVLQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVN 300

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 332 LGFGDIACLAHHLSAAAFNgsdlgSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVKE 411
Cdd:PRK08849 301 LGFKDVDVLLAETEKQGVL-----NDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKT 375


                 ....*.
gi 701332187 412 QIMAFA 417
Cdd:PRK08849 376 QVLKYA 381
PRK08013 PRK08013
oxidoreductase; Provisional
 15-414 8.32e-57

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 191.80  E-value: 8.32e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAGPRKEYDrMPDSYSNRVSSVSPGSATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAMIVFEKDD--LDDMGY 92
Cdd:PRK08013  28 RVAVLEQRVPEPLA-ADAPPALRVSAINAASEKLLTRLGVWQDILARRASCYHGMEVWDKDSFGRIAFDDQSmgYSHLGH 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  93 IVENDVIMSALTKQLDAVADrvevfyesravgYTWPLPSHSSDTSpWVQ----IQLADGRRLQTKLLIGADGHNSVVRKK 168
Cdd:PRK08013 107 IIENSVIHYALWQKAQQSSD------------ITLLAPAELQQVA-WGEneafLTLKDGSMLTARLVVGADGANSWLRNK 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 169 AEIKNIEHQYDQSAVVATLHLSEATDNnVAWQRFLPTGPIALLPLSD-TASSLVWSTSHEHASELLSMDEESFVDSINSA 247
Cdd:PRK08013 174 ADIPLTFWDYQHHALVATIRTEEPHDA-VARQVFHGDGILAFLPLSDpHLCSIVWSLSPEEAQRMQQAPEEEFNRALAIA 252

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 248 FwsnvnhsdfiDTAgamfrsaisllkpsgtaarqlppsVARVDPES-RAMFPLGMGHATEYVQHRVALIGDAAHRVHPLA 326
Cdd:PRK08013 253 F----------DNR------------------------LGLCELESeRQVFPLTGRYARQFAAHRLALVGDAAHTIHPLA 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 327 GQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNAL 406
Cdd:PRK08013 299 GQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSAALMLAGMQGFRDLFAGNNPAKKLLRDIGLKLADTL 378


                 ....*...
gi 701332187 407 PPVKEQIM 414
Cdd:PRK08013 379 PGVKPQLI 386
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 15-410 2.34e-56

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 190.45  E-value: 2.34e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAgpRKEYDRMPDSYSNRVSSVSPGSATLLSSFGAWDHVcSLRLKPFRRMQVWDACSEAMIVFEKDD--LDDMGY 92
Cdd:PRK05732  31 PVALIEA--FAPESDAHPGFDARAIALAAGTCQQLARLGVWQAL-ADCATPITHIHVSDRGHAGFVRLDAEDygVPALGY 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  93 IVENDVIMSALTKQLDavadrvevfyesRAVGYTWPLPSHSSDTSP---WVQIQLADGRRLQTKLLIGADGHNSVVRKKA 169
Cdd:PRK05732 108 VVELHDVGQRLFALLD------------KAPGVTLHCPARVANVERtqgSVRVTLDDGETLTGRLLVAADGSHSALREAL 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 170 EIKNIEHQYDQSAVVATLHLSEATDNnVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSINSAF- 248
Cdd:PRK05732 176 GIDWQQHPYEQVAVIANVTTSEAHQG-RAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSWSDAQFLAELQQAFg 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 249 WSnvnhsdfidtAGAMfrsaisllkpsgTAARQlppsvarvdpesRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQ 328
Cdd:PRK05732 255 WR----------LGRI------------THAGK------------RSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQ 300

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 329 GVNLGFGDIACLAHHLSAAAFNGSDLGSLKHLLKFETERQ--RHNVslIAAIDVLKRLYSTRLAPLVLLRTWGLQATNAL 406
Cdd:PRK05732 301 GFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQqdREAT--IGFTDGLVRLFANRWAPLVVGRNLGLMAMDLL 378


                 ....
gi 701332187 407 PPVK 410
Cdd:PRK05732 379 PPAR 382
PRK09126 PRK09126
FAD-dependent hydroxylase;
45-413 4.68e-44

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 157.80  E-value: 4.68e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  45 SATLLSSFGAWDHVCSLRLKPFRRMQVWDACSEAMIVF--EKDDLDDMGYIVENDVIMSALtkqLDAVA--DRVEVFYES 120
Cdd:PRK09126  56 SREILQRLGAWDRIPEDEISPLRDAKVLNGRSPFALTFdaRGRGADALGYLVPNHLIRRAA---YEAVSqqDGIELLTGT 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 121 RAvgytwplpSHSSDTSPWVQIQLADGRRLQTKLLIGADGHNSVVRKKAEIKNIEHQYDQSAVVATLHlSEATDNNVAWQ 200
Cdd:PRK09126 133 RV--------TAVRTDDDGAQVTLANGRRLTARLLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMR-HELPHHHTAWE 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 201 RFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFVDSINSAFWsnvnhsdfiDTAGAMfrsaisllkpsgtaaR 280
Cdd:PRK09126 204 WFGYGQTLALLPLNGHLSSLVLTLPPDQIEALLALDPEAFAAEVTARFK---------GRLGAM---------------R 259

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 281 QLppsvarvdpESRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLSAAAFNGSDLGSLKHL 360
Cdd:PRK09126 260 LV---------SSRHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAASLL 330

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 701332187 361 LKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVKEQI 413
Cdd:PRK09126 331 ERYERKHRLATRPLYHATNAIAALYTDDRPPARLLRRAVLRAANRFPPLKQAI 383
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 15-410 7.12e-44

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 155.48  E-value: 7.12e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAGPRKEYDRmpdsysnRVSSVSPGSATLLSSFGAWDHVCSLRLkPFRRMQVWDACSEAMI--VFEKDDLDDMGY 92
Cdd:COG0654   28 RVTVVERAPPPRPDG-------RGIALSPRSLELLRRLGLWDRLLARGA-PIRGIRVRDGSDGRVLarFDAAETGLPAGL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  93 IVENDVIMSALTKQLDAvaDRVEVFYESRAVGYTWplpshSSDTspwVQIQLADGRRLQTKLLIGADGHNSVVRKKAEIK 172
Cdd:COG0654  100 VVPRADLERALLEAARA--LGVELRFGTEVTGLEQ-----DADG---VTVTLADGRTLRADLVVGADGARSAVRRLLGIG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 173 NIEHQYDQSAVVATLHlseatdnnVAWQRFLptgpiallplsdtasslvwstshehasellsmdeesfvdsinsafwsnv 252
Cdd:COG0654  170 FTGRDYPQRALWAGVR--------TELRARL------------------------------------------------- 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 253 nhsdfidtagamfrsaisllkpsgtaaRQLPPSVARV-DPESRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVN 331
Cdd:COG0654  193 ---------------------------AAAGPRLGELlELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGAN 245

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 701332187 332 LGFGDIACLAHHLsAAAFNGSDLGSLkhLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVK 410
Cdd:COG0654  246 LALRDAAALAWKL-AAALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
15-413 1.07e-38

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 143.67  E-value: 1.07e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  15 KIALLEAgprkeydRMPDSYSN--RVSSVSPGSATLLSSFGAWdhvcSLRLKPFRRMQVWDACSEAMIVFEKDDLD--DM 90
Cdd:PRK06996  40 SIALIDA-------REPAASANdpRAIALSHGSRVLLETLGAW----PADATPIEHIHVSQRGHFGRTLIDRDDHDvpAL 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  91 GYIVENDVIMSALTKQLDAVADRVEVFYESRAvgytwplPSHSSDTSPWVQIQLADGRRLQTKLLIGADGHNSVVRKKAE 170
Cdd:PRK06996 109 GYVVRYGSLVAALARAVRGTPVRWLTSTTAHA-------PAQDADGVTLALGTPQGARTLRARIAVQAEGGLFHDQKADA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 171 IKNIEHQ-YDQSAVVATLHLSeATDNNVAWQRFLPTGPIALLPLSDTAS---SLVWSTSHEHASELLSMDEESFVDSINS 246
Cdd:PRK06996 182 GDSARRRdYGQTAIVGTVTVS-APRPGWAWERFTHEGPLALLPLGGPRQadyALVWCCAPDEAARRAALPDDAFLAELGA 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 247 AFWSNVNHsdFIDTAGamfrsaisllkpsgtaarqlppsvarvdpesRAMFPLGMGHATEYVQHRVALIGDAAHRVHPLA 326
Cdd:PRK06996 261 AFGTRMGR--FTRIAG-------------------------------RHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVA 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 327 GQGVNLGFGDIACLAHHLSAAAFNGSDLGSlkhllkFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNAL 406
Cdd:PRK06996 308 GQGLNLGLRDAHTLADALSDHGATPLALAT------FAARRALDRRVTIGATDLLPRLFTVDSRPLAHLRGAALTALEFV 381


                 ....*..
gi 701332187 407 PPVKEQI 413
Cdd:PRK06996 382 PPLKHAL 388
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
28-414 8.01e-36

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 135.42  E-value: 8.01e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  28 DRMPDSYSNRVSSVSPGSATLLSSFGAWDHvCSLRLKPFRRMQVWDACS---EAMIV-FEKDD--LDDMGYIVENDVIMS 101
Cdd:PRK07494  37 APEPPYADLRTTALLGPSIRFLERLGLWAR-LAPHAAPLQSMRIVDATGrliRAPEVrFRAAEigEDAFGYNIPNWLLNR 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 102 ALTKQLDAVADRVEVFYESRAVgytwplpsHSSDTSpwVQIQLADGRRLQTKLLIGADGHNSVVRKKAEIKNIEHQYDQS 181
Cdd:PRK07494 116 ALEARVAELPNITRFGDEAESV--------RPREDE--VTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQK 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 182 AVV-ATLHlsEATDNNVAWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFvdsinsafwsnvnhsdfidt 260
Cdd:PRK07494 186 ALVlNFTH--SRPHQNVSTEFHTEGGPFTQVPLPGRRSSLVWVVRPAEAERLLALSDAAL-------------------- 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 261 AGAMFRSAISLLkpsgtaarqlppsvARVDPES-RAMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIAC 339
Cdd:PRK07494 244 SAAIEERMQSML--------------GKLTLEPgRQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVAT 309

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 701332187 340 LAHHLSAaafNGSDLGSLKHLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVKEQIM 414
Cdd:PRK07494 310 LVEIVED---RPEDPGSAAVLAAYDRARRPDILSRTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFM 381
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 37-417 6.31e-30

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 119.26  E-value: 6.31e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  37 RVSSVSPGSATLLSSFGAWDHvcslrLKPF-RRMQ---VWDACSEAMIVFEKDDLDDMGYIVEND----VIMSALTKQ-L 107
Cdd:PRK06617  45 RTTALTPHSKNFLFSIDIWEE-----LEKFvAEMQdiyVVDNKASEILDLRNDADAVLGYVVKNSdfkkILLSKITNNpL 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 108 DAVADRVEvfYESravgytwpLPSHSSDTspwvqIQLADGRRLQTKLLIGADGHNSVVRKKAEIKNIEHQYDQSAVVATL 187
Cdd:PRK06617 120 ITLIDNNQ--YQE--------VISHNDYS-----IIKFDDKQIKCNLLIICDGANSKVRSHYFANEIEKPYQTALTFNIK 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 188 HlsEATDNNVAWQRFLPTGPIALLPLSDT-ASSLVWSTSHEHASELLSMDeesfvdsinsafwsnVNHSDFIDTAGAmfr 266
Cdd:PRK06617 185 H--EKPHENCAMEHFLPLGPFALLPLKDQyASSVIWSTSSDQAALIVNLP---------------VEEVRFLTQRNA--- 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 267 saisllkpsGTAARQLPpsvarVDPESRAmFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLSA 346
Cdd:PRK06617 245 ---------GNSLGKIT-----IDSEISS-FPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSN 309

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 701332187 347 aafNGSdlgslkhLLKFETERQRHNVSLIAAIDVLKRLYSTRLAPLVLLRTWGLQATNALPPVKEQIMAFA 417
Cdd:PRK06617 310 ---NGT-------LQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYA 370
PRK07045 PRK07045
putative monooxygenase; Reviewed
 141-397 8.67e-13

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 69.17  E-value: 8.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 141 QIQLADGRRLQTKLLIGADGHNSVVRKKA-EIKNIEHQYDQSAVVATLHLSEA--------TDNNVAWQRFLPTGpiall 211
Cdd:PRK07045 143 SVTLSDGERVAPTVLVGADGARSMIRDDVlRMPAERVPYATPMAFGTIALTDSvrecnrlyVDSNQGLAYFYPIG----- 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 212 plsDTASSLVWSTSHEHASELLSmdeesfvDSINSAFWSNVNHSDFIDTAGAMfrSAIsllkpsgTAARQLPpsvarvdp 291
Cdd:PRK07045 218 ---DQATRLVVSFPADEMQGYLA-------DTTRTKLLARLNEFVGDESADAM--AAI-------GAGTAFP-------- 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 292 esraMFPLGMGHATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDI----ACLAHHLSAAafngsdLGSLKHLLKFETER 367
Cdd:PRK07045 271 ----LIPLGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAgelgACLDLHLSGQ------IALADALERFERIR 340

                        250       260       270
                 ....*....|....*....|....*....|
gi 701332187 368 QRHNVSLIAAIDVLKRLYSTRLAPLVLLRT 397
Cdd:PRK07045 341 RPVNEAVISYGHALATTYHDRAALVANFRS 370
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 147-370 5.51e-10

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 60.42  E-value: 5.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  147 GRRLQTKLLIGADGHNSVVRKKAEIKNIEHQYDQSAVVATLHLS------EATDNNVAWQRFLPTGPIALLPLSDTASS- 219
Cdd:pfam01494 145 EYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWRSAGREr 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  220 ----LVWSTSHEHASELLSMDEesfvdsinsafwsnvnhsdfidtagamfrsaisllkpsgtAARQLPPSVA--RVDPES 293
Cdd:pfam01494 225 yyvqVPWDEEVEERPEEFTDEE----------------------------------------LKQRLRSIVGidLALVEI 264

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 701332187  294 RAMFPLGMGH--ATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLsAAAFNGSDLGSLkhLLKFETERQRH 370
Cdd:pfam01494 265 LWKSIWGVASrvATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKL-AAVLRGQAGESL--LDTYSAERLPV 340
PRK06834 PRK06834
hypothetical protein; Provisional
 114-336 1.38e-07

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 53.48  E-value: 1.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 114 VEVFYESRAVGYTwplpshSSDTSpwVQIQLADGRRLQTKLLIGADGHNSVVRKKAEIKNIEHQYDQSAVVATLHLSEAT 193
Cdd:PRK06834 115 VPIYRGREVTGFA------QDDTG--VDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEP 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 194 DNNV--------AWQRFLPTGPIALLPLSDTASSLVWSTSHEHASELLSMDEESFvdSINSAFWSnvnhSDFIDTAgamf 265
Cdd:PRK06834 187 EWGVhrdalgihAFGRLEDEGPVRVMVTEKQVGATGEPTLDDLREALIAVYGTDY--GIHSPTWI----SRFTDMA---- 256

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 701332187 266 rsaisllkpsgtaaRQlppsvarvdpesramfplgmghATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGD 336
Cdd:PRK06834 257 --------------RQ----------------------AASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQD 291
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
12-183 1.36e-06

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 49.58  E-value: 1.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  12 HDKKIALLEagpRKEYDRmpdsYSNRVSSVSPGSATLLSSFGAWDHVCSlrlkPFRRMQVWdACSEAMIVFEKDDldDMG 91
Cdd:COG0644   15 AGLSVLLLE---KGSFPG----DKICGGGLLPRALEELEPLGLDEPLER----PVRGARFY-SPGGKSVELPPGR--GGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187  92 YIVENDVIMSALTKQldAVADRVEVFYESRAVGYTWplpshssdTSPWVQIQLADGRRLQTKLLIGADGHNSVVRKKAEI 171
Cdd:COG0644   81 YVVDRARFDRWLAEQ--AEEAGAEVRTGTRVTDVLR--------DDGRVVVRTGDGEEIRADYVVDADGARSLLARKLGL 150

                        170
                 ....*....|..
gi 701332187 172 KNIEHQYDQSAV 183
Cdd:COG0644  151 KRRSDEPQDYAL 162
PRK06847 PRK06847
hypothetical protein; Provisional
 140-348 5.82e-05

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 44.86  E-value: 5.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 140 VQIQLADGRRLQTKLLIGADGHNSVVRKKAEIKNIEHQY-DQSAVVATLHLSEATDNNVAWQRflPTGPIALLPLSDTAS 218
Cdd:PRK06847 140 VTVTFSDGTTGRYDLVVGADGLYSKVRSLVFPDEPEPEYtGQGVWRAVLPRPAEVDRSLMYLG--PTTKAGVVPLSEDLM 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 219 SLVWStshEHASELLSMDEESFVDsinsafwsnvnhsdfidtagaMFRsaiSLLKP-SGTAARQLppsVARVDPESRAMF 297
Cdd:PRK06847 218 YLFVT---EPRPDNPRIEPDTLAA---------------------LLR---ELLAPfGGPVLQEL---REQITDDAQVVY 267

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 701332187 298 -PLGmGHATEYVQH--RVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLSAAA 348
Cdd:PRK06847 268 rPLE-TLLVPAPWHrgRVVLIGDAAHATTPHLAQGAGMAIEDAIVLAEELARHD 320
PRK06185 PRK06185
FAD-dependent oxidoreductase;
314-415 6.45e-05

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 44.85  E-value: 6.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 314 LIGDAAHRVHPLAGQGVNLGFGDIACLAHHLSAAAFNGSdlGSLKHLLKFETERQRHnVSLIAAIDVL---KRLYSTRLA 390
Cdd:PRK06185 288 CIGDAAHAMSPVGGVGINLAIQDAVAAANILAEPLRRGR--VSDRDLAAVQRRREFP-TRVTQALQRRiqrRLLAPALAG 364

                         90       100
                 ....*....|....*....|....*
gi 701332187 391 PLVLLRTWGLQATNALPPVKeQIMA 415
Cdd:PRK06185 365 RGPLGPPLLLRLLNRLPWLR-RLPA 388
PRK08244 PRK08244
monooxygenase;
114-385 6.74e-05

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 45.12  E-value: 6.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 114 VEVFYESRAVGYtwplpsHSSDTSPWVQIQLADGRRLQTKL-LIGADGHNSVVRKKAEIKNIEHQYDQSAVVATLHLSEA 192
Cdd:PRK08244 115 VEIFRGAEVLAV------RQDGDGVEVVVRGPDGLRTLTSSyVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDP 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 193 TDNNVAwQRFLPTGPIALLPLSDTASSLVWSTSHE-HASELLSMDEESFvdsinsafwsnvnHSDFIDTAGAMFR-SAIS 270
Cdd:PRK08244 189 PPSSVL-SLCTREGGVMIVPLSGGIYRVLIIDPERpQVPKDEPVTLEEL-------------KTSLIRICGTDFGlNDPV 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 271 LLKPSGTAARQlppsvarvdpesramfplgmghATEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLsAAAFN 350
Cdd:PRK08244 255 WMSRFGNATRQ----------------------AERYRSGRIFLAGDAAHIHFPAGGQGLNVGLQDAMNLGWKL-AAAIK 311

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 701332187 351 GSDLGSLkhLLKFETERQRHNVSLIAAIDVLKRLY 385
Cdd:PRK08244 312 GWAPDWL--LDSYHAERHPVGTALLRNTEVQTKLF 344
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
311-398 1.09e-04

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 44.13  E-value: 1.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 311 RVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLsAAAFNGSDLGSLkhLLKFETERQRHNVSLIAAIDVLKRLYSTRLA 390
Cdd:PRK06183 287 RVLLAGDAAHLMPPFAGQGMNSGIRDAANLAWKL-AAVLRGRAGDAL--LDTYEQERRPHARAMIDLAVRLGRVICPTDR 363


                 ....*...
gi 701332187 391 PLVLLRTW 398
Cdd:PRK06183 364 LAAALRDA 371
PRK06753 PRK06753
hypothetical protein; Provisional
 140-375 9.82e-04

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 41.21  E-value: 9.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 140 VQIQLADGRRLQTKLLIGADGHNSVVRKKAEiKNIEHQYDQ----SAVVATLHLSEATDNNVAWQrflPTGPIALLPLSD 215
Cdd:PRK06753 129 VTIHFADGESEAFDLCIGADGIHSKVRQSVN-ADSKVRYQGytcfRGLIDDIDLKLPDCAKEYWG---TKGRFGIVPLLN 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 216 tasslvwstshehasellsmdeesfvdsiNSAFWsnvnhsdFIdTAGAMFRSAI--SLLKPSGTAA-RQLPPSVARV-DP 291
Cdd:PRK06753 205 -----------------------------NQAYW-------FI-TINAKERDPKysSFGKPHLQAYfNHYPNEVREIlDK 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 701332187 292 ES-RAMF--------PLgmghaTEYVQHRVALIGDAAHRVHPLAGQGVNLGFGDIACLAHHLSAAAFNgsdlgslKHLLK 362
Cdd:PRK06753 248 QSeTGILhhdiydlkPL-----KSFVYGRIVLLGDAAHATTPNMGQGAGQAMEDAIVLANCLNAYDFE-------KALQR 315

                        250
                 ....*....|...
gi 701332187 363 FETERQRHNVSLI 375
Cdd:PRK06753 316 YDKIRVKHTAKVI 328
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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