|
Name |
Accession |
Description |
Interval |
E-value |
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-310 |
4.68e-126 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 364.86 E-value: 4.68e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTISILTT-SPEADE-------------PVNYVKGVIQHY--RGGPVPGFSAVIASDIPLGGGLS 64
Cdd:COG0153 45 AIDRGTYAAARPRDDRKVRVYSAdFDEEVEfdlddlepgeedgWANYVRGVAWALqeRGYKLGGFDLVIDGDVPLGAGLS 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 65 SSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLTDASLAV 144
Cdd:COG0153 125 SSAALEVAVALALNDLFGLGLDPVELAKIGQRAENEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLEGYAL 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 145 LITNSNVRHTLTGSEYPTRRQQCcEEAAAALGKASLRDATMAELEGGDGpSLGSGRSS-------GQQERTAQAAQALQD 217
Cdd:COG0153 205 VIVDTNVKHSLADSEYNERRAEC-EAAAAILGVKSLRDVTLEDLEAARA-RLGDEVLRrrarhvvTENQRVLEAVEALRA 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 218 RDYRMFGKLMVESHNSLRDDYEVSCPELDELVAAALEVDGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQEKY----N 293
Cdd:COG0153 283 GDLEAFGKLMNASHASLRDDYEVSCPELDTLVELALAEAGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYaektG 362
|
330
....*....|....*..
gi 700412334 294 GTATFYLTKPSGGAKVL 310
Cdd:COG0153 363 LEPDFYVVKPSDGARRL 379
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
32-310 |
1.82e-94 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 284.51 E-value: 1.82e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 32 NYVKGVIQHY--RGGPVPGFSAVIASDIPLGGGLSSSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIM 109
Cdd:PRK05101 94 NYVRGVVKHLqeRNPDFGGADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLPLSGAEIALNGQEAENQFVGCNCGIM 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 110 DQFISVMGKEGHALLIDCRSLESVLVPLTDaSLAVLITNSNVRHTLTGSEYPTRRQQcCEEAAAALGKASLRDATMAELE 189
Cdd:PRK05101 174 DQLISALGKKDHALLIDCRSLETKAVPMPE-GVAVVIINSNVKRGLVDSEYNTRRQQ-CETAARFFGVKALRDVTLEQFN 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 190 GGDG--PSLGSGRSS---GQQERTAQAAQALQDRDYRMFGKLMVESHNSLRDDYEVSCPELD---ELVAAALEVDGvyGS 261
Cdd:PRK05101 252 AVAAelDPVVAKRARhviTENARTLEAASALAAGDLKRMGELMAESHASMRDDFEITVPQIDtlvEIVKAVIGDQG--GV 329
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 700412334 262 RMTGGGFGGCTVTLLEARAAERAQRHIQEKYNGT----ATFYLTKPSGGAKVL 310
Cdd:PRK05101 330 RMTGGGFGGCIVALVPEELVEAVRQAVAEQYEAKtglkETFYVCKASQGAGQC 382
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
1-310 |
5.69e-88 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 268.23 E-value: 5.69e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTISILTTS----------------PEADEPVNYVKGVIQHY--RGGPVP-GFSAVIASDIPLGG 61
Cdd:TIGR00131 44 AIDFGTLCAVAVRDDKNVRIYLANadnkfaersldlpldgSEVSDWANYFKGVLHVAqeRFNSFPlGADIVCSGNVPTGS 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 62 GLSSSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLTDAS 141
Cdd:TIGR00131 124 GLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAENHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQLG 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 142 LAVLITNSNVRHTLTGSEYPTRRQQcCEEAAAALGK---ASLRDATMAELEGGDGPS-----LGSGRSS---GQQERTAQ 210
Cdd:TIGR00131 204 IAFVIANTNVKRTLAPSNYNTRRQE-CTTAANFLAAtdkGALRDFMNEYFARYIARLtkmlpLVEERAKhvvSENLRVLK 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 211 AAQALQDRDYRMFGKLMVESHNSLRDDYEVSCPELDELVAAALEVDGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQE 290
Cdd:TIGR00131 283 AVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDELVCSAALVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVAD 362
|
330 340
....*....|....*....|....
gi 700412334 291 KYNGT----ATFYLTKPSGGAKVL 310
Cdd:TIGR00131 363 KYPKKtgleLTFYVIVSKPGAGSC 386
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
211-293 |
5.98e-12 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 60.56 E-value: 5.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 211 AAQALQDRDYRMFGKLMVESHNSL--RDDYEVSCPELDELVAAALEVDgvYGSRMTGGGFGGCTVTLLE-ARAAERAQRH 287
Cdd:pfam08544 1 LLEALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELG--LGAKLSGSGGGPTVFALFKdEDDAEEVARA 78
|
....*.
gi 700412334 288 IQEKYN 293
Cdd:pfam08544 79 LREAGK 84
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-310 |
4.68e-126 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 364.86 E-value: 4.68e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTISILTT-SPEADE-------------PVNYVKGVIQHY--RGGPVPGFSAVIASDIPLGGGLS 64
Cdd:COG0153 45 AIDRGTYAAARPRDDRKVRVYSAdFDEEVEfdlddlepgeedgWANYVRGVAWALqeRGYKLGGFDLVIDGDVPLGAGLS 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 65 SSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLTDASLAV 144
Cdd:COG0153 125 SSAALEVAVALALNDLFGLGLDPVELAKIGQRAENEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLEGYAL 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 145 LITNSNVRHTLTGSEYPTRRQQCcEEAAAALGKASLRDATMAELEGGDGpSLGSGRSS-------GQQERTAQAAQALQD 217
Cdd:COG0153 205 VIVDTNVKHSLADSEYNERRAEC-EAAAAILGVKSLRDVTLEDLEAARA-RLGDEVLRrrarhvvTENQRVLEAVEALRA 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 218 RDYRMFGKLMVESHNSLRDDYEVSCPELDELVAAALEVDGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQEKY----N 293
Cdd:COG0153 283 GDLEAFGKLMNASHASLRDDYEVSCPELDTLVELALAEAGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYaektG 362
|
330
....*....|....*..
gi 700412334 294 GTATFYLTKPSGGAKVL 310
Cdd:COG0153 363 LEPDFYVVKPSDGARRL 379
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
32-310 |
1.82e-94 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 284.51 E-value: 1.82e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 32 NYVKGVIQHY--RGGPVPGFSAVIASDIPLGGGLSSSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIM 109
Cdd:PRK05101 94 NYVRGVVKHLqeRNPDFGGADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLPLSGAEIALNGQEAENQFVGCNCGIM 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 110 DQFISVMGKEGHALLIDCRSLESVLVPLTDaSLAVLITNSNVRHTLTGSEYPTRRQQcCEEAAAALGKASLRDATMAELE 189
Cdd:PRK05101 174 DQLISALGKKDHALLIDCRSLETKAVPMPE-GVAVVIINSNVKRGLVDSEYNTRRQQ-CETAARFFGVKALRDVTLEQFN 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 190 GGDG--PSLGSGRSS---GQQERTAQAAQALQDRDYRMFGKLMVESHNSLRDDYEVSCPELD---ELVAAALEVDGvyGS 261
Cdd:PRK05101 252 AVAAelDPVVAKRARhviTENARTLEAASALAAGDLKRMGELMAESHASMRDDFEITVPQIDtlvEIVKAVIGDQG--GV 329
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 700412334 262 RMTGGGFGGCTVTLLEARAAERAQRHIQEKYNGT----ATFYLTKPSGGAKVL 310
Cdd:PRK05101 330 RMTGGGFGGCIVALVPEELVEAVRQAVAEQYEAKtglkETFYVCKASQGAGQC 382
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
1-310 |
5.69e-88 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 268.23 E-value: 5.69e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTISILTTS----------------PEADEPVNYVKGVIQHY--RGGPVP-GFSAVIASDIPLGG 61
Cdd:TIGR00131 44 AIDFGTLCAVAVRDDKNVRIYLANadnkfaersldlpldgSEVSDWANYFKGVLHVAqeRFNSFPlGADIVCSGNVPTGS 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 62 GLSSSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLTDAS 141
Cdd:TIGR00131 124 GLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAENHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQLG 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 142 LAVLITNSNVRHTLTGSEYPTRRQQcCEEAAAALGK---ASLRDATMAELEGGDGPS-----LGSGRSS---GQQERTAQ 210
Cdd:TIGR00131 204 IAFVIANTNVKRTLAPSNYNTRRQE-CTTAANFLAAtdkGALRDFMNEYFARYIARLtkmlpLVEERAKhvvSENLRVLK 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 211 AAQALQDRDYRMFGKLMVESHNSLRDDYEVSCPELDELVAAALEVDGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQE 290
Cdd:TIGR00131 283 AVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDELVCSAALVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVAD 362
|
330 340
....*....|....*....|....
gi 700412334 291 KYNGT----ATFYLTKPSGGAKVL 310
Cdd:TIGR00131 363 KYPKKtgleLTFYVIVSKPGAGSC 386
|
|
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
1-310 |
3.17e-81 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 250.93 E-value: 3.17e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTI----------SILTTS------PEADEPVNYVKGVIQHY--RGGPVP-GFSAVIASDIPLGG 61
Cdd:PRK05322 46 AITLGTYGAARKRDDKKVrlysanfedlGIIEFDlddlsfDKEDDWANYPKGVLKFLqeAGYKIDhGFDILIYGNIPNGA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 62 GLSSSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLTDAS 141
Cdd:PRK05322 126 GLSSSASIELLTGVILKDLFNLDLDRLELVKLGQKTENEFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYVPLDLGD 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 142 LAVLITNSNVRHTLTGSEYPTRRQQcCEEAAAALGK----ASLRDATMAELEG-----GDGPSLGSGRSS-GQQERTAQA 211
Cdd:PRK05322 206 YVIVIMNTNKRRELADSKYNERRAE-CEKALEELQKkldiKSLGELTEEEFDEysyliKDETLLKRARHAvTENQRTLKA 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 212 AQALQDRDYRMFGKLMVESHNSLRDDYEVSCPELDELVAAALEVDGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQEK 291
Cdd:PRK05322 285 VKALKAGDLEKFGRLMNASHVSLRDDYEVTGLELDTLVEAAWKQEGVLGARMTGAGFGGCAIAIVKKDKVEAFKENVGKA 364
|
330 340
....*....|....*....|...
gi 700412334 292 YNGT----ATFYLTKPSGGAKVL 310
Cdd:PRK05322 365 YEEKigyaASFYVAEIGDGAREL 387
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
1-310 |
3.20e-77 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 239.51 E-value: 3.20e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTI------SILTTSPEADEPVN----YVKGVI-----QHYRGGPVPGFsavIASDIPLGGGLSS 65
Cdd:PRK03817 27 AINLYTFLEIEKSEKFIFysenfnEEKTFELDKLEKLNswadYIKGVIwvlekRGYEVGGVKGK---VSSNLPIGAGLSS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 66 SAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLTDaSLAVL 145
Cdd:PRK03817 104 SASLEVAVAYALNEAYNLNLSKLELALLAREAENEFVGVPCGIMDQFAVAFGKKDHAIFLDTMTLEYEYVPFPE-DYEIL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 146 ITNSNVRHTLTGSEYPTRRQQcCEEAAAALGKASLRDATMAELEGgdGPSLGSGRSS---GQQERTAQAAQALQDRDYRM 222
Cdd:PRK03817 183 VFDTGVKRELASSEYNERRQE-CEEALKILGKKSSKEVTEEDLSK--LPPLLRKRAGyvlRENERVLKVRDALKEGDIET 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 223 FGKLMVESHNSLRDDYEVSCPELDELVAAALEVdGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQEKY----NGTATF 298
Cdd:PRK03817 260 LGELLTESHWDLADNYEVSCEELDFFVEFALEL-GAYGARLTGAGFGGSAIALVDKGKFESIGEELLEEYkkrfGIDPKY 338
|
330
....*....|..
gi 700412334 299 YLTKPSGGAKVL 310
Cdd:PRK03817 339 FVVESSDGVRKI 350
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
1-283 |
2.17e-53 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 178.52 E-value: 2.17e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTISIltTSPEADEPV---------------NYVKGVIQHYR--GGPVPGFSAVIASDIPLGGGL 63
Cdd:PRK00555 29 ALPQRTVVTFTPEHTDAITA--SSDRADGSAripldttpgqvtgwaAYAAGVIWALRgaGHPVPGGAMSITSDVEIGSGL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 64 SSSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLT--DAS 141
Cdd:PRK00555 107 SSSAALECAVLGAVGAATGTRIDRLEQARLAQRAENEYVGAPTGLLDQLAALFGAPKTALLIDFRDLTVRPVAFDpdAAG 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 142 LAVLITNSNVRHTLTGSEYPTRRQQcCEEAAAALGKASLRDATMAELEG----GDGPSLGSGRSS-GQQERTAQAAQALQ 216
Cdd:PRK00555 187 VVLLLMDSRARHRHAGGEYAARRAS-CERAAADLGVSSLRAVQDRGLAAlgaiADPIDARRARHVlTENQRVLDFAAALA 265
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 700412334 217 DRDYRMFGKLMVESHNSLRDDYEVSCPELDELVAAALEVdGVYGSRMTGGGFGGCTVTLLEARAAER 283
Cdd:PRK00555 266 DSDFTAAGQLLTASHASMRDDFEITTERIDLIADSAVRA-GALGARMTGGGFGGCVIALVPADRAED 331
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
45-312 |
6.01e-30 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 118.00 E-value: 6.01e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 45 PVPGFSAVIASDIPLGGGLSSSAALEVA----------------------TYTFLQQlCPDDgDLVAKALACQKAEHTFA 102
Cdd:PTZ00290 131 SLQGVCMVVHGTLPMGAGMSASASFGVAllnaintvvtrrykgcptspgrRYSILPP-MSKE-ELIELAKQARRIETEFC 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 103 SMPCGIMDQFISVMGKEGHALLIDCRSL--ESV-LVPLTDASLAVLITNSNVRHTLTGSE---YPTRRQQCcEEAAAALG 176
Cdd:PTZ00290 209 GVNVGIMDQFISAFAEEDKFMFLDCKSLtfESHdMTPLLGDGACFLLIDSMIKHDLLGGTagmYNTVRSDQ-EGAQKKIG 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 177 KASLRDA--TMAELE------GGDG------PSLGSGRSSGQQER-TAQAAQALQDRDYRMF----------------GK 225
Cdd:PTZ00290 288 KHRYRGKpfTFSDLVrnpkkyTFDGdvvafmESCKPLMTPGEFERgTYNIMEQIRTLEFIKLndpelplsreerfrkaGE 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 226 LMVESHNSLRDDYEVSCPELDELVAAALEVDGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQEKYNG----TATFYLT 301
Cdd:PTZ00290 368 ILNAGHQGMRDLMKITTPELDFIHELINEEKGVAGGRMMGGGFGGCIILLLKKNAVDRVVAHVREKFKArfgvENDVYPV 447
|
330
....*....|.
gi 700412334 302 KPSGGAKVLPL 312
Cdd:PTZ00290 448 VAGDGAFVVSL 458
|
|
| PLN02865 |
PLN02865 |
galactokinase |
24-310 |
9.77e-29 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 114.13 E-value: 9.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 24 SPEADEPVNYVKGVIQHYRGGPV---PGFSAVIASDIPL-GGGLSSSAALEVAtytFLQQLcPDDGDLVAKALAC----Q 95
Cdd:PLN02865 103 SKEESNWGDYARGAVYALQSRGHalsQGITGYISGSEGLdSSGLSSSAAVGVA---YLLAL-ENANNLTVSPEDNieldR 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 96 KAEHTFASMPCGIMDQFISVMGKEGHALLIDCRSLESVLVPLTDA------SLAVLITNSNVRHTLTGSEYPTRRQQCCE 169
Cdd:PLN02865 179 LIENEYLGLRNGILDQSAILLSRYGCLTFMDCKTLDHKLVSLQFQqpggekPFKILLAFSGLRHALTNKPGYNLRVSECQ 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 170 EAAAALGKASLRDATMAELEGGD-----------GPSLGSGRSSGQQE--RTAQAAQALQDRDYRMFGKLMVESHNSLRD 236
Cdd:PLN02865 259 EAARFLLEASGNDELEPLLCNVEpevyeahkcklEAVLARRAEHYFSEnmRVIKGVEAWASGNLEEFGKLISASGLSSIE 338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 237 DYEVSCPELDELVAAALEVDGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQEKY-----------NGTATFYLTKPSG 305
Cdd:PLN02865 339 NYECGCEPLIQLYEILLKAPGVYGARFSGAGFRGCCVAFVDAEMAEEAASFVRDEYekaqpelasniNGDKPVLICEAGD 418
|
....*
gi 700412334 306 GAKVL 310
Cdd:PLN02865 419 CARVL 423
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
1-275 |
1.79e-23 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 97.22 E-value: 1.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGTISI--------LTTSPEADEPVNYVKGVIQ---HYRGGPVPGFSAVIASDIPLGGGLSSSAAL 69
Cdd:COG1577 23 AVDRRATVTVEPSDDDKLRIespdlggtLDLDPLADAALRYIKAAIEaalEYLGLPLKGFDIEIDSEIPRKRGLGSSAAV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 70 EVATYTFLQQLC---PDDGDLVAKALACQKAEHTFASMpcgiMDQFISVMgkeGHALLIDCRSLESVLVPLTDASLAVLI 146
Cdd:COG1577 103 AVAVIRALAAFYgveLSKEELFKLALEAEKIVHGNPSG----LDTAASTY---GGPIYYQRGDRAEPLELPKNLPLVVGD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 147 TN--SNVRHTLTG-----SEYPTRRQQCCEEAAAAlgkaslrdatmaeleggdgpslgsgrssgqqerTAQAAQALQDRD 219
Cdd:COG1577 176 TGvpASTKELVAKvrklkERNPELYEAFLEEIGDL---------------------------------VEEAIEALEEGD 222
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 700412334 220 YRMFGKLMVESHNsLRDDYEVSCPELDELVAAALEVdGVYGSRMTGGGFGGCTVTL 275
Cdd:COG1577 223 LEALGELMNENHG-LLRALGVSTPELDRLVEAARKA-GALGAKLTGAGGGGCVIAL 276
|
|
| PLN02521 |
PLN02521 |
galactokinase |
32-310 |
2.34e-22 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 96.70 E-value: 2.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 32 NYV----KGVIQHYR------GGPVpGFSAVIASDIPLGGGLSSSAALEVATYTFLqqlcpddgdLVAKALACQKAEHTF 101
Cdd:PLN02521 124 NYFicgyKGVFEFLKskgvdvGPPV-GLDVVVDGTVPTGSGLSSSAALVCSAAIAI---------MAALGLNFTKKEVAQ 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 102 ASMPC--------GIMDQFISVMGKEGHALLIDCRSLESVLVPLTDA-------SLAV------LITNSNVR-------- 152
Cdd:PLN02521 194 FTCKCerhigtqsGGMDQAISIMAQQGVAKLIDFNPVRATDVQLPAGgtfvianSLAEsnkavtAATNYNNRvvecrlaa 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 153 ------------------HTLTGSEyptrrqQCCEEAAAALGKASLRDA----------TMAELEGGDGPSLGSGRSSGQ 204
Cdd:PLN02521 274 ivlavklgmsaeeaiskvKTLSDVE------GLCVSFAGSHGSSDPAVAvkellhegpyTAEEIEEILGESLTSIFKNSP 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 205 --------------QERTA----QAAQALQDRD-----------YRMFGKLMVESHNSLRDDYEVSCPELDELVAAALEv 255
Cdd:PLN02521 348 tslavlkaakhfklHQRAVhvysEAKRVHAFRDtvssslseeekLKKLGDLMNESHYSCSVLYECSCPELEELVKVCRD- 426
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 700412334 256 DGVYGSRMTGGGFGGCTVTLLEARAAERAQRHIQEKY-------------NGTATFYLTKPSGGAKVL 310
Cdd:PLN02521 427 NGALGARLTGAGWGGCAVALVKEAIVPQFILALKEKFyksriekgvikeeDLGLYVFASKPSSGAAIL 494
|
|
| mevalon_kin |
TIGR00549 |
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ... |
47-275 |
5.67e-16 |
|
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain] Cd Length: 273 Bit Score: 76.18 E-value: 5.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 47 PGFSAVIASDIPLGGGLSSSAALEVATYTFLQQLCPDDGDLVAKALACQKAEHTFASMPCGImDQFISVMGkegHALLID 126
Cdd:TIGR00549 77 PPLEITIESEIPPGRGLGSSAAVAVALIRALADYFGSELSKEELAELANEAEKIAHGKPSGI-DTATSTSG---GPVYFE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 127 CRSLESVLVPLTDASLavLITNSNV-RHTltgSEYPTRRQQCCEEAAAALgkaslrDATMAELEggdgpslgsgrssgqq 205
Cdd:TIGR00549 153 KGEGEFTKLISLDGYF--VIADTGVsGST---KEAVARVRQLLERFPELI------DSIMDAIG---------------- 205
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 206 ERTAQAAQALQDRDYRMFGKLMVESHnSLRDDYEVSCPELDELVAAALEVdGVYGSRMTGGGFGGCTVTL 275
Cdd:TIGR00549 206 ELTLEAKAALQDGDVESLGELMNINQ-GLLKALGVSHPKLDQLVEIARKA-GALGAKLTGAGGGGCMIAL 273
|
|
| PRK03926 |
PRK03926 |
mevalonate kinase; Provisional |
1-275 |
3.46e-15 |
|
mevalonate kinase; Provisional
Pssm-ID: 179677 [Multi-domain] Cd Length: 302 Bit Score: 74.32 E-value: 3.46e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 1 ALQLGTVLVGSPTQDGtISILTTSPEADEPVNYVKGVIQHYRG-GPVPGFSAVIASDIPLGGGLSSSAALEVATYTFLQQ 79
Cdd:PRK03926 28 AIDLRTYVRAEFNDDS-IYIESDYGKTGEKHPYVSAAIEKMREeADKDGVTVSITSQIPVGSGLGSSAAVTVATIGALNR 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 80 L--CPDDGDLVAKALACQKAEHTFASMPcgiMDQFISVMGkeGHALLIDCRSLesvlvPLTDASLAVLITNS-------- 149
Cdd:PRK03926 107 LlgLGLSLEEIAKLGHKVELLVQGAASP---TDTYVSTMG--GFVTIPDRKKL-----PFPECGIVVGYTGSsgstkelv 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 150 -NVRHTLTgsEYPtrrqQCCEEAAAALGKASLRdatmaeleggdgpslgsgrssgqqertaqAAQALQDRDYRMFGKLMV 228
Cdd:PRK03926 177 aNVRKLKE--EYP----ELIEPILSSIGKISEK-----------------------------GEELILSGDYVSLGELMN 221
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 700412334 229 ESHnSLRDDYEVSCPELDELVAAALEVdGVYGSRMTGGGFGGCTVTL 275
Cdd:PRK03926 222 INQ-GLLDALGVSTKELSELIYAARTA-GALGAKITGAGGGGCMVAL 266
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
211-293 |
5.98e-12 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 60.56 E-value: 5.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700412334 211 AAQALQDRDYRMFGKLMVESHNSL--RDDYEVSCPELDELVAAALEVDgvYGSRMTGGGFGGCTVTLLE-ARAAERAQRH 287
Cdd:pfam08544 1 LLEALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELG--LGAKLSGSGGGPTVFALFKdEDDAEEVARA 78
|
....*.
gi 700412334 288 IQEKYN 293
Cdd:pfam08544 79 LREAGK 84
|
|
| GHMP_kinases_N |
pfam00288 |
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ... |
52-118 |
6.00e-11 |
|
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 395225 [Multi-domain] Cd Length: 64 Bit Score: 57.17 E-value: 6.00e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 700412334 52 VIASDIPLGGGLSSSAALEVATYTFLQQLCPDDGdlvakALACQKAEHTFASMPCGIMDQFISVMGK 118
Cdd:pfam00288 3 EIESNIPLGAGLGSSAALAVALLLALNELFGLPL-----AKLALEAEELAGGGRGGGMDVAASLYGG 64
|
|
| PTZ00298 |
PTZ00298 |
mevalonate kinase; Provisional |
210-286 |
1.77e-06 |
|
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain] Cd Length: 328 Bit Score: 48.70 E-value: 1.77e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 700412334 210 QAAQALQDRDYRMFGKLMVESHNSLRdDYEVSCPELDELVAAALEvDGVYGSRMTGGGFGGCTVTLlearAAERAQR 286
Cdd:PTZ00298 229 EAKEALQKGNLFRVGELMNANHDLCQ-KLTVSCRELDSIVQTCRT-YGALGAKMSGTGRGGLVVAL----AASEDQR 299
|
|
| ThrB |
COG0083 |
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the ... |
1-68 |
1.66e-03 |
|
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 439853 [Multi-domain] Cd Length: 302 Bit Score: 39.31 E-value: 1.66e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 700412334 1 ALQLGTVLVGSPTQDGTISILTTSPEADE----PVNYVKGVIQHYR---GGPVPGFSAVIASDIPLGGGLSSSAA 68
Cdd:COG0083 24 ALSLYDEVEVERSDEPGLEIEIEGEGADElptdEDNLVYQAALALLeklGKEPPGLRIEIEKGIPLGRGLGSSAA 98
|
|
|