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Conserved domains on  [gi|645277882|ref|XP_008243978|]
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PREDICTED: cell division control protein 48 homolog D [Prunus mume]

Protein Classification

CDC48 family AAA ATPase( domain architecture ID 1001098)

CDC48 family AAA ATPase is involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; similar to yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CDC48 super family cl36852
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
30-768 0e+00

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


The actual alignment was detected with superfamily member TIGR01243:

Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 775.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882   30 RLVVDDAINDD--NSVVALHPDTMEKLQLFRGDTILI-KVR*****ICIALADDTCEEPKIRMNKVVRSNLRVRLGDVVS 106
Cdd:TIGR01243   3 ELRVAEAYPRDvgRGIVRIDRQTAARLGVEPGDFVEIeKGDRSVVAIVWPLRPDDEGRGIIRMDGYLRANAGVTIGDTVT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  107 VHQcADVKYGKRVHILPvddTIEGVTGNLFDAYLKPYFLEayRPVRKGDLFLVRGGMRSVEFKVIETDPSEYCVVAPDTE 186
Cdd:TIGR01243  83 VER-AEVKEAKKVVLAP---TQPIRFGRDFVDYVKEFLLG--KPISKGETVIVPVLEGALPFVVVSTQPAGFVYVTEATE 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  187 IFCEGEPVKREDEERLNEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANET 266
Cdd:TIGR01243 157 VEIREKPVREEIERKVPKVTYEDIGGLKEAKEKIREMVELPMKHPELFEHLGIEPPKGVLLYGPPGTGKTLLAKAVANEA 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  267 GAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVI 346
Cdd:TIGR01243 237 GAYFISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKGRGRVI 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  347 VMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQC 426
Cdd:TIGR01243 317 VIGATNRPDALDPALRRPGRFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLDKLAEVTHGFVGADLAALAKEAAMAA 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  427 IREKMDV--IDLEDEEIDAEILNSMAVTNEHFKTALGTSNPSALRETVVEVPNVSWEDIGGLDNVKRELQETVQYPVEHP 504
Cdd:TIGR01243 397 LRRFIREgkINFEAEEIPAEVLKELKVTMKDFMEALKMVEPSAIREVLVEVPNVRWSDIGGLEEVKQELREAVEWPLKHP 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  505 EKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSAPCVLFFDELD 584
Cdd:TIGR01243 477 EIFEKMGIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEID 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  585 SIATQRGSSVGDAggAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSC 664
Cdd:TIGR01243 557 AIAPARGARFDTS--VTDRIVNQLLTEMDGIQELSNVVVIAATNRPDILDPALLRPGRFDRLILVPPPDEEARKEIFKIH 634
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  665 LRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIRENIEKDIErerrrsENPEAMEEDVDDEVaEIRAAHFEESM 744
Cdd:TIGR01243 635 TRSMPLAEDVDLEELAEMTEGYTGADIEAVCREAAMAALRESIGSPAK------EKLEVGEEEFLKDL-KVEMRHFLEAL 707
                         730       740
                  ....*....|....*....|....
gi 645277882  745 KYARRSVSDADIRKYQAFAQTLQQ 768
Cdd:TIGR01243 708 KKVKPSVSKEDMLRYERLAKELKR 731
 
Name Accession Description Interval E-value
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
30-768 0e+00

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 775.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882   30 RLVVDDAINDD--NSVVALHPDTMEKLQLFRGDTILI-KVR*****ICIALADDTCEEPKIRMNKVVRSNLRVRLGDVVS 106
Cdd:TIGR01243   3 ELRVAEAYPRDvgRGIVRIDRQTAARLGVEPGDFVEIeKGDRSVVAIVWPLRPDDEGRGIIRMDGYLRANAGVTIGDTVT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  107 VHQcADVKYGKRVHILPvddTIEGVTGNLFDAYLKPYFLEayRPVRKGDLFLVRGGMRSVEFKVIETDPSEYCVVAPDTE 186
Cdd:TIGR01243  83 VER-AEVKEAKKVVLAP---TQPIRFGRDFVDYVKEFLLG--KPISKGETVIVPVLEGALPFVVVSTQPAGFVYVTEATE 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  187 IFCEGEPVKREDEERLNEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANET 266
Cdd:TIGR01243 157 VEIREKPVREEIERKVPKVTYEDIGGLKEAKEKIREMVELPMKHPELFEHLGIEPPKGVLLYGPPGTGKTLLAKAVANEA 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  267 GAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVI 346
Cdd:TIGR01243 237 GAYFISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKGRGRVI 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  347 VMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQC 426
Cdd:TIGR01243 317 VIGATNRPDALDPALRRPGRFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLDKLAEVTHGFVGADLAALAKEAAMAA 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  427 IREKMDV--IDLEDEEIDAEILNSMAVTNEHFKTALGTSNPSALRETVVEVPNVSWEDIGGLDNVKRELQETVQYPVEHP 504
Cdd:TIGR01243 397 LRRFIREgkINFEAEEIPAEVLKELKVTMKDFMEALKMVEPSAIREVLVEVPNVRWSDIGGLEEVKQELREAVEWPLKHP 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  505 EKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSAPCVLFFDELD 584
Cdd:TIGR01243 477 EIFEKMGIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEID 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  585 SIATQRGSSVGDAggAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSC 664
Cdd:TIGR01243 557 AIAPARGARFDTS--VTDRIVNQLLTEMDGIQELSNVVVIAATNRPDILDPALLRPGRFDRLILVPPPDEEARKEIFKIH 634
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  665 LRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIRENIEKDIErerrrsENPEAMEEDVDDEVaEIRAAHFEESM 744
Cdd:TIGR01243 635 TRSMPLAEDVDLEELAEMTEGYTGADIEAVCREAAMAALRESIGSPAK------EKLEVGEEEFLKDL-KVEMRHFLEAL 707
                         730       740
                  ....*....|....*....|....
gi 645277882  745 KYARRSVSDADIRKYQAFAQTLQQ 768
Cdd:TIGR01243 708 KKVKPSVSKEDMLRYERLAKELKR 731
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
489-649 3.99e-121

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 361.06  E-value: 3.99e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 489 VKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFD 568
Cdd:cd19528    1 VKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 569 KARGSAPCVLFFDELDSIATQRGSSVGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIY 648
Cdd:cd19528   81 KARAAAPCVLFFDELDSIAKARGGNIGDAGGAADRVINQILTEMDGMNTKKNVFIIGATNRPDIIDPAILRPGRLDQLIY 160

                 .
gi 645277882 649 I 649
Cdd:cd19528  161 I 161
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
438-708 7.94e-118

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 359.32  E-value: 7.94e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 438 DEEIDAEILNSMAVTNEHFKTALGTSNPsalretvVEVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKG 517
Cdd:COG1222   42 LEEAPALLLNDANLTQKRLGTPRGTAVP-------AESPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKG 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 518 VLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGda 597
Cdd:COG1222  115 VLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSKYIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDGT-- 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 598 GGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIR 677
Cdd:COG1222  193 SGEVQRTVNQLLAELDGFESRGDVLIIAATNRPDLLDPALLRPGRFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLD 272
                        250       260       270
                 ....*....|....*....|....*....|.
gi 645277882 678 ALAKYTQGFSGADITEICQRACKYAIRENIE 708
Cdd:COG1222  273 KLAKLTEGFSGADLKAIVTEAGMFAIREGRD 303
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
204-438 7.53e-96

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 304.06  E-value: 7.53e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 204 EVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLA 283
Cdd:PRK03992 127 NVTYEDIGGLEEQIREVREAVELPLKKPELFEEVGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSELVQKFI 206
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 284 GESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKR--EKTHGEVE-RRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPA 360
Cdd:PRK03992 207 GEGARLVRELFELAREKAPSIIFIDEIDAIAAKRtdSGTSGDREvQRTLMQLLAEMDGFDPRGNVKIIAATNRIDILDPA 286
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 361 LRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLED 438
Cdd:PRK03992 287 ILRPGRFDRIIEVPLPDEEGRLEILKIHTRKMNLADDVDLEELAELTEGASGADLKAICTEAGMFAIRDDRTEVTMED 364
cell_div_CdvC NF041006
cell division protein CdvC;
444-762 1.35e-61

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 212.29  E-value: 1.35e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 444 EILNSMAVTNEhfkTALGTSNPSALRETVVEVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEkfgMSPSKGVLFYGP 523
Cdd:NF041006  69 EVLEELVPAEP---AGPDVEKESDEELVVKEKPKVTFSDIVGLEDVKEALKEAIVYPSKRPDLFP---LGWPRGILLYGP 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 524 PGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSA-----PCVLFFDELDSIAtqrGSSVGDAG 598
Cdd:NF041006 143 PGCGKTMLAAAVANEIDSEFIHVDAASIMSKWLGEAEKNVAKIFKKAREKSkeegkPAIIFIDEIDALL---GVYSSEVG 219
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 599 GAAdRVLNQLLTEMDGMTAKKT---VFIIGATNRPDIIDPALLRpgRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVD 675
Cdd:NF041006 220 GEV-RVRNQFLKEMDGLQDKSEnyhVYVIGATNKPWRLDEPFLR--RFQKRIYIPLPDREQRLELLKYYTSKIKLENDVD 296
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 676 IRALAKYTQGFSGADITEICQRACKYAIRENIEKDIERERrrsenPEAMEEdvddevaeiraahFEESMKYARRSVSDAD 755
Cdd:NF041006 297 LDELAEMTEGYTASDIRDIVQAAHMRVVKEMFEKGLGEPR-----PITMED-------------FKEVLKIRKPSVNQEM 358

                 ....*..
gi 645277882 756 IRKYQAF 762
Cdd:NF041006 359 LKAYEAW 365
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
245-375 8.47e-55

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 184.72  E-value: 8.47e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  245 ILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEV 324
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDSE 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 645277882  325 ERRIVSQLLTLMDGLKSRAH-VIVMGATNRPNSIDPALRrfGRFDREIDIGV 375
Cdd:pfam00004  81 SRRVVNQLLTELDGFTSSNSkVIVIAATNRPDKLDPALL--GRFDRIIEFPL 130
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
241-377 3.15e-20

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 87.81  E-value: 3.15e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882   241 PPKGILLYGPPGSGKTLIARAVANE---TGAFFFCINGPEIMS--------------KLAGESESNLRKAFEEAEKNAPS 303
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARElgpPGGGVIYIDGEDILEevldqllliivggkKASGSGELRLRLALALARKLKPD 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 645277882   304 IIFIDEIDSIAPKREKthgevERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFgRFDREIDIGVPD 377
Cdd:smart00382  81 VLILDEITSLLDAEQE-----ALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRR-RFDRRIVLLLIL 148
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
518-552 3.19e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 40.15  E-value: 3.19e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 645277882 518 VLFYGPPGCGKTLLAKAIANE-CQAN----FISVkgPELL 552
Cdd:NF038214  93 VLLLGPPGTGKTHLAIALGYAaCRQGyrvrFTTA--ADLV 130
 
Name Accession Description Interval E-value
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
30-768 0e+00

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 775.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882   30 RLVVDDAINDD--NSVVALHPDTMEKLQLFRGDTILI-KVR*****ICIALADDTCEEPKIRMNKVVRSNLRVRLGDVVS 106
Cdd:TIGR01243   3 ELRVAEAYPRDvgRGIVRIDRQTAARLGVEPGDFVEIeKGDRSVVAIVWPLRPDDEGRGIIRMDGYLRANAGVTIGDTVT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  107 VHQcADVKYGKRVHILPvddTIEGVTGNLFDAYLKPYFLEayRPVRKGDLFLVRGGMRSVEFKVIETDPSEYCVVAPDTE 186
Cdd:TIGR01243  83 VER-AEVKEAKKVVLAP---TQPIRFGRDFVDYVKEFLLG--KPISKGETVIVPVLEGALPFVVVSTQPAGFVYVTEATE 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  187 IFCEGEPVKREDEERLNEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANET 266
Cdd:TIGR01243 157 VEIREKPVREEIERKVPKVTYEDIGGLKEAKEKIREMVELPMKHPELFEHLGIEPPKGVLLYGPPGTGKTLLAKAVANEA 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  267 GAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVI 346
Cdd:TIGR01243 237 GAYFISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKGRGRVI 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  347 VMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQC 426
Cdd:TIGR01243 317 VIGATNRPDALDPALRRPGRFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLDKLAEVTHGFVGADLAALAKEAAMAA 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  427 IREKMDV--IDLEDEEIDAEILNSMAVTNEHFKTALGTSNPSALRETVVEVPNVSWEDIGGLDNVKRELQETVQYPVEHP 504
Cdd:TIGR01243 397 LRRFIREgkINFEAEEIPAEVLKELKVTMKDFMEALKMVEPSAIREVLVEVPNVRWSDIGGLEEVKQELREAVEWPLKHP 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  505 EKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSAPCVLFFDELD 584
Cdd:TIGR01243 477 EIFEKMGIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEID 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  585 SIATQRGSSVGDAggAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSC 664
Cdd:TIGR01243 557 AIAPARGARFDTS--VTDRIVNQLLTEMDGIQELSNVVVIAATNRPDILDPALLRPGRFDRLILVPPPDEEARKEIFKIH 634
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  665 LRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIRENIEKDIErerrrsENPEAMEEDVDDEVaEIRAAHFEESM 744
Cdd:TIGR01243 635 TRSMPLAEDVDLEELAEMTEGYTGADIEAVCREAAMAALRESIGSPAK------EKLEVGEEEFLKDL-KVEMRHFLEAL 707
                         730       740
                  ....*....|....*....|....
gi 645277882  745 KYARRSVSDADIRKYQAFAQTLQQ 768
Cdd:TIGR01243 708 KKVKPSVSKEDMLRYERLAKELKR 731
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
489-649 3.99e-121

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 361.06  E-value: 3.99e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 489 VKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFD 568
Cdd:cd19528    1 VKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 569 KARGSAPCVLFFDELDSIATQRGSSVGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIY 648
Cdd:cd19528   81 KARAAAPCVLFFDELDSIAKARGGNIGDAGGAADRVINQILTEMDGMNTKKNVFIIGATNRPDIIDPAILRPGRLDQLIY 160

                 .
gi 645277882 649 I 649
Cdd:cd19528  161 I 161
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
438-708 7.94e-118

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 359.32  E-value: 7.94e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 438 DEEIDAEILNSMAVTNEHFKTALGTSNPsalretvVEVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKG 517
Cdd:COG1222   42 LEEAPALLLNDANLTQKRLGTPRGTAVP-------AESPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKG 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 518 VLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGda 597
Cdd:COG1222  115 VLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSKYIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDGT-- 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 598 GGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIR 677
Cdd:COG1222  193 SGEVQRTVNQLLAELDGFESRGDVLIIAATNRPDLLDPALLRPGRFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLD 272
                        250       260       270
                 ....*....|....*....|....*....|.
gi 645277882 678 ALAKYTQGFSGADITEICQRACKYAIRENIE 708
Cdd:COG1222  273 KLAKLTEGFSGADLKAIVTEAGMFAIREGRD 303
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
190-438 9.00e-117

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 356.24  E-value: 9.00e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 190 EGEPVKREDEERLNEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAF 269
Cdd:COG1222   60 LGTPRGTAVPAESPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKGVLLYGPPGTGKTLLAKAVAGELGAP 139
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 270 FFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKR--EKTHGEVeRRIVSQLLTLMDGLKSRAHVIV 347
Cdd:COG1222  140 FIRVRGSELVSKYIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRtdDGTSGEV-QRTVNQLLAELDGFESRGDVLI 218
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 348 MGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCI 427
Cdd:COG1222  219 IAATNRPDLLDPALLRPGRFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLDKLAKLTEGFSGADLKAIVTEAGMFAI 298
                        250
                 ....*....|.
gi 645277882 428 REKMDVIDLED 438
Cdd:COG1222  299 REGRDTVTMED 309
RecA-like_CDC48_r1-like cd19519
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ...
209-374 1.40e-116

first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410927 [Multi-domain]  Cd Length: 166  Bit Score: 349.81  E-value: 1.40e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESES 288
Cdd:cd19519    1 DIGGCRKQLAQIREMVELPLRHPELFKAIGIKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESES 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 289 NLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFD 368
Cdd:cd19519   81 NLRKAFEEAEKNAPAIIFIDEIDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFD 160

                 ....*.
gi 645277882 369 REIDIG 374
Cdd:cd19519  161 REIDIG 166
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
209-373 1.78e-100

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 307.68  E-value: 1.78e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESES 288
Cdd:cd19503    1 DIGGLDEQIASLKELIELPLKYPELFRALGLKPPRGVLLHGPPGTGKTLLARAVANEAGANFLSISGPSIVSKYLGESEK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 289 NLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFD 368
Cdd:cd19503   81 NLREIFEEARSHAPSIIFIDEIDALAPKREEDQREVERRVVAQLLTLMDGMSSRGKVVVIAATNRPDAIDPALRRPGRFD 160

                 ....*
gi 645277882 369 REIDI 373
Cdd:cd19503  161 REVEI 165
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
489-649 3.94e-97

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 298.81  E-value: 3.94e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 489 VKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFD 568
Cdd:cd19511    1 VKRELKEAVEWPLKHPDAFKRLGIRPPKGVLLYGPPGCGKTLLAKALASEAGLNFISVKGPELFSKYVGESERAVREIFQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 569 KARGSAPCVLFFDELDSIATQRGSSvgDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIY 648
Cdd:cd19511   81 KARQAAPCIIFFDEIDSLAPRRGQS--DSSGVTDRVVSQLLTELDGIESLKGVVVIAATNRPDMIDPALLRPGRLDKLIY 158

                 .
gi 645277882 649 I 649
Cdd:cd19511  159 V 159
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
317-717 6.65e-96

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 304.53  E-value: 6.65e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 317 REKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAE 396
Cdd:COG0464    2 AELLALAVALALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLAL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 397 DVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLEDEEIDAEILNSMAVTNEHFKTalgtsnpsaLRETVVEVP 476
Cdd:COG0464   82 LAALLSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGG---------LEEELLELR 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 477 NVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWF 556
Cdd:COG0464  153 EAILDDLGGLEEVKEELRELVALPLKRPELREEYGLPPPRGLLLYGPPGTGKTLLARALAGELGLPLIEVDLSDLVSKYV 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 557 GESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSvgdAGGAADRVLNQLLTEMDGMTAKktVFIIGATNRPDIIDPA 636
Cdd:COG0464  233 GETEKNLREVFDKARGLAPCVLFIDEADALAGKRGEV---GDGVGRRVVNTLLTEMEELRSD--VVVIAATNRPDLLDPA 307
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 637 LLRpgRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIRENIE----KDIE 712
Cdd:COG0464  308 LLR--RFDEIIFFPLPDAEERLEIFRIHLRKRPLDEDVDLEELAEATEGLSGADIRNVVRRAALQALRLGREpvttEDLL 385

                 ....*
gi 645277882 713 RERRR 717
Cdd:COG0464  386 EALER 390
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
204-438 7.53e-96

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 304.06  E-value: 7.53e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 204 EVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLA 283
Cdd:PRK03992 127 NVTYEDIGGLEEQIREVREAVELPLKKPELFEEVGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSELVQKFI 206
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 284 GESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKR--EKTHGEVE-RRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPA 360
Cdd:PRK03992 207 GEGARLVRELFELAREKAPSIIFIDEIDAIAAKRtdSGTSGDREvQRTLMQLLAEMDGFDPRGNVKIIAATNRIDILDPA 286
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 361 LRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLED 438
Cdd:PRK03992 287 ILRPGRFDRIIEVPLPDEEGRLEILKIHTRKMNLADDVDLEELAELTEGASGADLKAICTEAGMFAIRDDRTEVTMED 364
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
472-724 1.52e-93

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 298.28  E-value: 1.52e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 472 VVEVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPEL 551
Cdd:PRK03992 122 VIESPNVTYEDIGGLEEQIREVREAVELPLKKPELFEEVGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSEL 201
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 552 LTMWFGESEANVREIFDKARGSAPCVLFFDELDSIATQR---GSSvGDAggAADRVLNQLLTEMDGMTAKKTVFIIGATN 628
Cdd:PRK03992 202 VQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIAAKRtdsGTS-GDR--EVQRTLMQLLAEMDGFDPRGNVKIIAATN 278
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 629 RPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIREN-- 706
Cdd:PRK03992 279 RIDILDPAILRPGRFDRIIEVPLPDEEGRLEILKIHTRKMNLADDVDLEELAELTEGASGADLKAICTEAGMFAIRDDrt 358
                        250       260
                 ....*....|....*....|....*....
gi 645277882 707 ----------IEKDI-ERERRRSENPEAM 724
Cdd:PRK03992 359 evtmedflkaIEKVMgKEEKDSMEEPGVM 387
26Sp45 TIGR01242
26S proteasome subunit P45 family; Many proteins may score above the trusted cutoff because an ...
197-438 4.79e-89

26S proteasome subunit P45 family; Many proteins may score above the trusted cutoff because an internal


Pssm-ID: 130309 [Multi-domain]  Cd Length: 364  Bit Score: 285.54  E-value: 4.79e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  197 EDEERLNeVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGP 276
Cdd:TIGR01242 112 EVEERPN-VSYEDIGGLEEQIREIREAVELPLKHPELFEEVGIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGS 190
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  277 EIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKR--EKTHGEVE-RRIVSQLLTLMDGLKSRAHVIVMGATNR 353
Cdd:TIGR01242 191 ELVRKYIGEGARLVREIFELAKEKAPSIIFIDEIDAIAAKRtdSGTSGDREvQRTLMQLLAELDGFDPRGNVKVIAATNR 270
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  354 PNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDV 433
Cdd:TIGR01242 271 PDILDPALLRPGRFDRIIEVPLPDFEGRLEILKIHTRKMKLAEDVDLEAIAKMTEGASGADLKAICTEAGMFAIREERDY 350

                  ....*
gi 645277882  434 IDLED 438
Cdd:TIGR01242 351 VTMDD 355
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
190-444 3.15e-86

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 279.10  E-value: 3.15e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 190 EGEPVKREDEERLNEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAF 269
Cdd:COG0464  139 EDIGGLEEELLELREAILDDLGGLEEVKEELRELVALPLKRPELREEYGLPPPRGLLLYGPPGTGKTLLARALAGELGLP 218
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 270 FFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRahVIVMG 349
Cdd:COG0464  219 LIEVDLSDLVSKYVGETEKNLREVFDKARGLAPCVLFIDEADALAGKRGEVGDGVGRRVVNTLLTEMEELRSD--VVVIA 296
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 350 ATNRPNSIDPALRRfgRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIRE 429
Cdd:COG0464  297 ATNRPDLLDPALLR--RFDEIIFFPLPDAEERLEIFRIHLRKRPLDEDVDLEELAEATEGLSGADIRNVVRRAALQALRL 374
                        250
                 ....*....|....*..
gi 645277882 430 KMDVIDLED--EEIDAE 444
Cdd:COG0464  375 GREPVTTEDllEALERE 391
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
489-649 2.55e-78

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 249.33  E-value: 2.55e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 489 VKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFD 568
Cdd:cd19529    1 VKQELKEAVEWPLLKPEVFKRLGIRPPKGILLYGPPGTGKTLLAKAVATESNANFISVKGPELLSKWVGESEKAIREIFR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 569 KARGSAPCVLFFDELDSIATQRGSSvGDAgGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIY 648
Cdd:cd19529   81 KARQVAPCVIFFDEIDSIAPRRGTT-GDS-GVTERVVNQLLTELDGLEEMNGVVVIAATNRPDIIDPALLRAGRFDRLIY 158

                 .
gi 645277882 649 I 649
Cdd:cd19529  159 I 159
FtsH_fam TIGR01241
ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct ...
187-442 1.70e-75

ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 273520 [Multi-domain]  Cd Length: 495  Bit Score: 253.75  E-value: 1.70e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  187 IFCEGEPVKREDEERLNEVGYDDVGGVRKQMAQIRELVELpLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANET 266
Cdd:TIGR01241  34 AFSFGKSKAKLLNEEKPKVTFKDVAGIDEAKEELMEIVDF-LKNPSKFTKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEA 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  267 GAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREK----THGEVERRIvSQLLTLMDGLKSR 342
Cdd:TIGR01241 113 GVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRGAglggGNDEREQTL-NQLLVEMDGFGTN 191
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  343 AHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEA 422
Cdd:TIGR01241 192 TGVIVIAATNRPDVLDPALLRPGRFDRQVVVDLPDIKGREEILKVHAKNKKLAPDVDLKAVARRTPGFSGADLANLLNEA 271
                         250       260
                  ....*....|....*....|..
gi 645277882  423 ALQCIREKMDVIDLED--EEID 442
Cdd:TIGR01241 272 ALLAARKNKTEITMNDieEAID 293
FtsH_fam TIGR01241
ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct ...
474-717 2.55e-74

ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 273520 [Multi-domain]  Cd Length: 495  Bit Score: 250.67  E-value: 2.55e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  474 EVPNVSWEDIGGLDNVKRELQETVQYpVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLT 553
Cdd:TIGR01241  48 EKPKVTFKDVAGIDEAKEELMEIVDF-LKNPSKFTKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVE 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  554 MWFGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDII 633
Cdd:TIGR01241 127 MFVGVGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRGAGLGGGNDEREQTLNQLLVEMDGFGTNTGVIVIAATNRPDVL 206
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  634 DPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIREN----IEK 709
Cdd:TIGR01241 207 DPALLRPGRFDRQVVVDLPDIKGREEILKVHAKNKKLAPDVDLKAVARRTPGFSGADLANLLNEAALLAARKNkteiTMN 286

                  ....*...
gi 645277882  710 DIERERRR 717
Cdd:TIGR01241 287 DIEEAIDR 294
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
486-649 6.36e-74

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 237.77  E-value: 6.36e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 486 LDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRE 565
Cdd:cd19530    1 LDHVREELTMSILRPIKRPDIYKALGIDLPTGVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERAVRQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 566 IFDKARGSAPCVLFFDELDSIATQRGssvGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQ 645
Cdd:cd19530   81 VFQRARASAPCVIFFDEVDALVPKRG---DGGSWASERVVNQLLTEMDGLEERSNVFVIAATNRPDIIDPAMLRPGRLDK 157

                 ....
gi 645277882 646 LIYI 649
Cdd:cd19530  158 TLYV 161
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
489-649 1.38e-73

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 237.03  E-value: 1.38e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 489 VKRELQETVQYPVEHPEKFEKfGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFD 568
Cdd:cd19527    1 VKKEILDTIQLPLEHPELFSS-GLRKRSGILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEANVREVFQ 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 569 KARGSAPCVLFFDELDSIATQRGSSvGDAGGAADRVLNQLLTEMDGM-TAKKTVFIIGATNRPDIIDPALLRPGRLDQLI 647
Cdd:cd19527   80 KARDAKPCVIFFDELDSLAPSRGNS-GDSGGVMDRVVSQLLAELDGMsSSGQDVFVIGATNRPDLLDPALLRPGRFDKLL 158

                 ..
gi 645277882 648 YI 649
Cdd:cd19527  159 YL 160
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
207-459 4.14e-72

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 242.75  E-value: 4.14e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 207 YDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGES 286
Cdd:PTZ00361 182 YADIGGLEQQIQEIKEAVELPLTHPELYDDIGIKPPKGVILYGPPGTGKTLLAKAVANETSATFLRVVGSELIQKYLGDG 261
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 287 ESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTH--GEVE-RRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRR 363
Cdd:PTZ00361 262 PKLVRELFRVAEENAPSIVFIDEIDAIGTKRYDATsgGEKEiQRTMLELLNQLDGFDSRGDVKVIMATNRIESLDPALIR 341
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 364 FGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKmdvidledeeida 443
Cdd:PTZ00361 342 PGRIDRKIEFPNPDEKTKRRIFEIHTSKMTLAEDVDLEEFIMAKDELSGADIKAICTEAGLLALRER------------- 408
                        250
                 ....*....|....*.
gi 645277882 444 eilnSMAVTNEHFKTA 459
Cdd:PTZ00361 409 ----RMKVTQADFRKA 420
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
205-438 4.18e-72

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 246.87  E-value: 4.18e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 205 VGYDDVGGVRKQMAQIRELVELpLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAG 284
Cdd:COG0465  139 VTFDDVAGVDEAKEELQEIVDF-LKDPEKFTRLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVG 217
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 285 ESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEV--ER-RIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPAL 361
Cdd:COG0465  218 VGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRGAGLGGGhdEReQTLNQLLVEMDGFEGNEGVIVIAATNRPDVLDPAL 297
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 645277882 362 RRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLED 438
Cdd:COG0465  298 LRPGRFDRQVVVDLPDVKGREAILKVHARKKPLAPDVDLEVIARRTPGFSGADLANLVNEAALLAARRNKKAVTMED 374
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
474-717 5.31e-72

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 241.21  E-value: 5.31e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 474 EVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLT 553
Cdd:PTZ00454 138 EKPDVTYSDIGGLDIQKQEIREAVELPLTCPELYEQIGIDPPRGVLLYGPPGTGKTMLAKAVAHHTTATFIRVVGSEFVQ 217
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 554 MWFGESEANVREIFDKARGSAPCVLFFDELDSIATQRgssvGDAGGAAD----RVLNQLLTEMDGMTAKKTVFIIGATNR 629
Cdd:PTZ00454 218 KYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKR----FDAQTGADrevqRILLELLNQMDGFDQTTNVKVIMATNR 293
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 630 PDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIREN--- 706
Cdd:PTZ00454 294 ADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFQTITSKMNLSEEVDLEDFVSRPEKISAADIAAICQEAGMQAVRKNryv 373
                        250
                 ....*....|..
gi 645277882 707 -IEKDIERERRR 717
Cdd:PTZ00454 374 iLPKDFEKGYKT 385
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
209-371 1.87e-71

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 231.52  E-value: 1.87e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESES 288
Cdd:cd19518    1 DIGGMDSTLKELCELLIHPILPPEYFQHLGVEPPRGVLLHGPPGCGKTMLANAIAGELKVPFLKISATEIVSGVSGESEE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 289 NLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLK----SRAHVIVMGATNRPNSIDPALRRF 364
Cdd:cd19518   81 KIRELFDQAISNAPCIVFIDEIDAITPKRESAQREMERRIVSQLLTCMDELNnektAGGPVLVIGATNRPDSLDPALRRA 160

                 ....*..
gi 645277882 365 GRFDREI 371
Cdd:cd19518  161 GRFDREI 167
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
476-716 2.24e-71

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 244.95  E-value: 2.24e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 476 PNVSWEDIGGLDNVKRELQETVQYpVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMW 555
Cdd:COG0465  137 PKVTFDDVAGVDEAKEELQEIVDF-LKDPEKFTRLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMF 215
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 556 FGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGdaGGAADR--VLNQLLTEMDGMTAKKTVFIIGATNRPDII 633
Cdd:COG0465  216 VGVGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRGAGLG--GGHDEReqTLNQLLVEMDGFEGNEGVIVIAATNRPDVL 293
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 634 DPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIREN------- 706
Cdd:COG0465  294 DPALLRPGRFDRQVVVDLPDVKGREAILKVHARKKPLAPDVDLEVIARRTPGFSGADLANLVNEAALLAARRNkkavtme 373
                        250
                 ....*....|....*.
gi 645277882 707 -IEKDIER-----ERR 716
Cdd:COG0465  374 dFEEAIDRviagpERK 389
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
482-649 9.71e-71

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 229.49  E-value: 9.71e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEA 561
Cdd:cd19503    1 DIGGLDEQIASLKELIELPLKYPELFRALGLKPPRGVLLHGPPGTGKTLLARAVANEAGANFLSISGPSIVSKYLGESEK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 562 NVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDAGgaaDRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPG 641
Cdd:cd19503   81 NLREIFEEARSHAPSIIFIDEIDALAPKREEDQREVE---RRVVAQLLTLMDGMSSRGKVVVIAATNRPDAIDPALRRPG 157

                 ....*...
gi 645277882 642 RLDQLIYI 649
Cdd:cd19503  158 RFDREVEI 165
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
480-722 7.36e-70

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 230.16  E-value: 7.36e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 480 WEDIGGLDNVKRELQETVQYpVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGES 559
Cdd:COG1223    1 LDDVVGQEEAKKKLKLIIKE-LRRRENLRKFGLWPPRKILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSLIGSYLGET 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 560 EANVREIFDKARgSAPCVLFFDELDSIATQRGSS--VGDAGgaadRVLNQLLTEMDGMTAKktVFIIGATNRPDIIDPAL 637
Cdd:COG1223   80 ARNLRKLFDFAR-RAPCVIFFDEFDAIAKDRGDQndVGEVK----RVVNALLQELDGLPSG--SVVIAATNHPELLDSAL 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 638 LRpgRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIRENIEK-------- 709
Cdd:COG1223  153 WR--RFDEVIEFPLPDKEERKEILELNLKKFPLPFELDLKKLAKKLEGLSGADIEKVLKTALKKAILEDREKvtkedlee 230
                        250
                 ....*....|....*
gi 645277882 710 --DIERERRRSENPE 722
Cdd:COG1223  231 alKQRKERKKEPKKE 245
ftsH CHL00176
cell division protein; Validated
478-709 2.15e-68

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 238.41  E-value: 2.15e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 478 VSWEDIGGLDNVKRELQETVQYpVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFG 557
Cdd:CHL00176 180 ITFRDIAGIEEAKEEFEEVVSF-LKKPERFTAVGAKIPKGVLLVGPPGTGKTLLAKAIAGEAEVPFFSISGSEFVEMFVG 258
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 558 ESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPAL 637
Cdd:CHL00176 259 VGAARVRDLFKKAKENSPCIVFIDEIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGFKGNKGVIVIAATNRVDILDAAL 338
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 645277882 638 LRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIRENIEK 709
Cdd:CHL00176 339 LRPGRFDRQITVSLPDREGRLDILKVHARNKKLSPDVSLELIARRTPGFSGADLANLLNEAAILTARRKKAT 410
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
489-648 3.16e-68

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 222.30  E-value: 3.16e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 489 VKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFD 568
Cdd:cd19526    1 VKKALEETIEWPSKYPKIFASSPLRLRSGILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNKYIGASEQNVRDLFS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 569 KARGSAPCVLFFDELDSIATQRGSsvgDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIY 648
Cdd:cd19526   81 RAQSAKPCILFFDEFDSIAPKRGH---DSTGVTDRVVNQLLTQLDGVEGLDGVYVLAATSRPDLIDPALLRPGRLDKLVY 157
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
219-371 1.85e-67

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 220.23  E-value: 1.85e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 219 QIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAE 298
Cdd:cd19511    4 ELKEAVEWPLKHPDAFKRLGIRPPKGVLLYGPPGCGKTLLAKALASEAGLNFISVKGPELFSKYVGESERAVREIFQKAR 83
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 645277882 299 KNAPSIIFIDEIDSIAPKR-EKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREI 371
Cdd:cd19511   84 QAAPCIIFFDEIDSLAPRRgQSDSSGVTDRVVSQLLTELDGIESLKGVVVIAATNRPDMIDPALLRPGRLDKLI 157
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
204-440 7.50e-66

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 224.64  E-value: 7.50e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 204 EVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLA 283
Cdd:PTZ00454 141 DVTYSDIGGLDIQKQEIREAVELPLTCPELYEQIGIDPPRGVLLYGPPGTGKTMLAKAVAHHTTATFIRVVGSEFVQKYL 220
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 284 GESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVER---RIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPA 360
Cdd:PTZ00454 221 GEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGADRevqRILLELLNQMDGFDQTTNVKVIMATNRADTLDPA 300
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 361 LRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLEDEE 440
Cdd:PTZ00454 301 LLRPGRLDRKIEFPLPDRRQKRLIFQTITSKMNLSEEVDLEDFVSRPEKISAADIAAICQEAGMQAVRKNRYVILPKDFE 380
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
479-647 2.04e-65

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 215.28  E-value: 2.04e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 479 SWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGE 558
Cdd:cd19502    1 TYEDIGGLDEQIREIREVVELPLKHPELFEELGIEPPKGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYIGE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 559 SEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALL 638
Cdd:cd19502   81 GARLVRELFEMAREKAPSIIFIDEIDAIGAKRFDSGTGGDREVQRTMLELLNQLDGFDPRGNIKVIMATNRPDILDPALL 160

                 ....*....
gi 645277882 639 RPGRLDQLI 647
Cdd:cd19502  161 RPGRFDRKI 169
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
478-649 3.87e-65

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 214.79  E-value: 3.87e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 478 VSWEDIGGLDNVKRELQETVQYpVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFG 557
Cdd:cd19501    1 VTFKDVAGCEEAKEELKEVVEF-LKNPEKFTKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 558 ESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPAL 637
Cdd:cd19501   80 VGASRVRDLFEQAKKNAPCIVFIDEIDAVGRKRGAGLGGGHDEREQTLNQLLVEMDGFESNTGVIVIAATNRPDVLDPAL 159
                        170
                 ....*....|..
gi 645277882 638 LRPGRLDQLIYI 649
Cdd:cd19501  160 LRPGRFDRQVYV 171
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
207-373 6.95e-65

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 214.12  E-value: 6.95e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 207 YDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGES 286
Cdd:cd19502    2 YEDIGGLDEQIREIREVVELPLKHPELFEELGIEPPKGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYIGEG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 287 ESNLRKAFEEAEKNAPSIIFIDEIDSIAPKR--EKTHGEVE-RRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRR 363
Cdd:cd19502   82 ARLVRELFEMAREKAPSIIFIDEIDAIGAKRfdSGTGGDREvQRTMLELLNQLDGFDPRGNIKVIMATNRPDILDPALLR 161
                        170
                 ....*....|
gi 645277882 364 FGRFDREIDI 373
Cdd:cd19502  162 PGRFDRKIEF 171
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
219-373 4.40e-64

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 211.20  E-value: 4.40e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 219 QIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAE 298
Cdd:cd19529    4 ELKEAVEWPLLKPEVFKRLGIRPPKGILLYGPPGTGKTLLAKAVATESNANFISVKGPELLSKWVGESEKAIREIFRKAR 83
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882 299 KNAPSIIFIDEIDSIAPKREKTHGE-VERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDI 373
Cdd:cd19529   84 QVAPCVIFFDEIDSIAPRRGTTGDSgVTERVVNQLLTELDGLEEMNGVVVIAATNRPDIIDPALLRAGRFDRLIYI 159
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
459-706 1.52e-63

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 224.91  E-value: 1.52e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 459 ALGTSNPSALRETVVEVpnvSWEDIGGLDNVKRELQETVQYpVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANE 538
Cdd:PRK10733 133 SFGKSKARMLTEDQIKT---TFADVAGCDEAKEEVAELVEY-LREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGE 208
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 539 CQANFISVKGPELLTMWFGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDAGGAADRVLNQLLTEMDGMTAK 618
Cdd:PRK10733 209 AKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGN 288
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 619 KTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRA 698
Cdd:PRK10733 289 EGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEA 368

                 ....*...
gi 645277882 699 CKYAIREN 706
Cdd:PRK10733 369 ALFAARGN 376
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
489-649 1.78e-63

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 209.45  E-value: 1.78e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 489 VKRELQETVQYPVEHPEKfEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFD 568
Cdd:cd19481    1 LKASLREAVEAPRRGSRL-RRYGLGLPKGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVGESEKNLRKIFE 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 569 KARGSAPCVLFFDELDSIATQRGSSVGDagGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIY 648
Cdd:cd19481   80 RARRLAPCILFIDEIDAIGRKRDSSGES--GELRRVLNQLLTELDGVNSRSKVLVIAATNRPDLLDPALLRPGRFDEVIE 157

                 .
gi 645277882 649 I 649
Cdd:cd19481  158 F 158
ftsH CHL00176
cell division protein; Validated
205-445 9.75e-63

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 222.62  E-value: 9.75e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 205 VGYDDVGGVRKQMAQIRELVELpLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAG 284
Cdd:CHL00176 180 ITFRDIAGIEEAKEEFEEVVSF-LKKPERFTAVGAKIPKGVLLVGPPGTGKTLLAKAIAGEAEVPFFSISGSEFVEMFVG 258
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 285 ESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREK----THGEVERrIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPA 360
Cdd:CHL00176 259 VGAARVRDLFKKAKENSPCIVFIDEIDAVGRQRGAgiggGNDEREQ-TLNQLLTEMDGFKGNKGVIVIAATNRVDILDAA 337
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 361 LRRFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLedEE 440
Cdd:CHL00176 338 LLRPGRFDRQITVSLPDREGRLDILKVHARNKKLSPDVSLELIARRTPGFSGADLANLLNEAAILTARRKKATITM--KE 415

                 ....*
gi 645277882 441 IDAEI 445
Cdd:CHL00176 416 IDTAI 420
cell_div_CdvC NF041006
cell division protein CdvC;
444-762 1.35e-61

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 212.29  E-value: 1.35e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 444 EILNSMAVTNEhfkTALGTSNPSALRETVVEVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEkfgMSPSKGVLFYGP 523
Cdd:NF041006  69 EVLEELVPAEP---AGPDVEKESDEELVVKEKPKVTFSDIVGLEDVKEALKEAIVYPSKRPDLFP---LGWPRGILLYGP 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 524 PGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSA-----PCVLFFDELDSIAtqrGSSVGDAG 598
Cdd:NF041006 143 PGCGKTMLAAAVANEIDSEFIHVDAASIMSKWLGEAEKNVAKIFKKAREKSkeegkPAIIFIDEIDALL---GVYSSEVG 219
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 599 GAAdRVLNQLLTEMDGMTAKKT---VFIIGATNRPDIIDPALLRpgRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVD 675
Cdd:NF041006 220 GEV-RVRNQFLKEMDGLQDKSEnyhVYVIGATNKPWRLDEPFLR--RFQKRIYIPLPDREQRLELLKYYTSKIKLENDVD 296
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 676 IRALAKYTQGFSGADITEICQRACKYAIRENIEKDIERERrrsenPEAMEEdvddevaeiraahFEESMKYARRSVSDAD 755
Cdd:NF041006 297 LDELAEMTEGYTASDIRDIVQAAHMRVVKEMFEKGLGEPR-----PITMED-------------FKEVLKIRKPSVNQEM 358

                 ....*..
gi 645277882 756 IRKYQAF 762
Cdd:NF041006 359 LKAYEAW 365
pup_AAA TIGR03689
proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some ...
474-734 2.70e-60

proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some proteins are modified by ligation between an epsilon-amino group of a lysine side chain and the C-terminal carboxylate of the ubiquitin-like protein Pup. This modification leads to protein degradation by the archaeal-like proteasome found in the Actinobacteria. Members of this protein family belong to the AAA family of ATPases and tend to be clustered with the genes for Pup, the Pup ligase PafA, and structural components of the proteasome. This protein forms hexameric rings with ATPase activity. [Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 200312 [Multi-domain]  Cd Length: 512  Bit Score: 212.65  E-value: 2.70e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  474 EVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANEC----------QANF 543
Cdd:TIGR03689 175 EVPDVTYADIGGLGSQIEQIRDAVELPFLHPELYREYGLKPPKGVLLYGPPGCGKTLIAKAVANSLaarigaegggKSYF 254
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  544 ISVKGPELLTMWFGESEANVREIFDKARGSA----PCVLFFDELDSIATQRGSSVgdAGGAADRVLNQLLTEMDGMTAKK 619
Cdd:TIGR03689 255 LNIKGPELLNKYVGETERQIRLIFQRAREKAsegrPVIVFFDEMDSLFRTRGSGV--SSDVETTVVPQLLAEIDGVESLD 332
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  620 TVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKS-PVSKD---------VDIRAL------AKYT 683
Cdd:TIGR03689 333 NVIVIGASNREDMIDPAILRPGRLDVKIRIERPDAEAAADIFAKYLTDDlPLPEDlaahdgdreATAAALiqrvvdALYA 412
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 645277882  684 QG-----------------------FSGADITEICQRACKYAIRENIEKdiereRRRSENPEAMEEDVDDEVAE 734
Cdd:TIGR03689 413 RSeanryvevtyangstevlyfadfVSGAMLANIVDRAKKRAIKDHITG-----GQVGLRAEHLLAAVEDEFRE 481
RecA-like_CDC48_r1-like cd19519
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ...
482-650 2.81e-60

first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410927 [Multi-domain]  Cd Length: 166  Bit Score: 201.13  E-value: 2.81e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEA 561
Cdd:cd19519    1 DIGGCRKQLAQIREMVELPLRHPELFKAIGIKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESES 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 562 NVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDaggAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPG 641
Cdd:cd19519   81 NLRKAFEEAEKNAPAIIFIDEIDAIAPKREKTHGE---VERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFG 157

                 ....*....
gi 645277882 642 RLDQLIYIP 650
Cdd:cd19519  158 RFDREIDIG 166
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
218-373 3.48e-60

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 200.59  E-value: 3.48e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 218 AQIRELVELPLRHPQLFKSiGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEA 297
Cdd:cd19481    3 ASLREAVEAPRRGSRLRRY-GLGLPKGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVGESEKNLRKIFERA 81
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 645277882 298 EKNAPSIIFIDEIDSIAPKREKT-HGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDI 373
Cdd:cd19481   82 RRLAPCILFIDEIDAIGRKRDSSgESGELRRVLNQLLTELDGVNSRSKVLVIAATNRPDLLDPALLRPGRFDEVIEF 158
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
472-705 1.25e-59

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 208.86  E-value: 1.25e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 472 VVEVPNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPEL 551
Cdd:PTZ00361 174 VDKAPLESYADIGGLEQQIQEIKEAVELPLTHPELYDDIGIKPPKGVILYGPPGTGKTLLAKAVANETSATFLRVVGSEL 253
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 552 LTMWFGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSvgDAGGAAD--RVLNQLLTEMDGMTAKKTVFIIGATNR 629
Cdd:PTZ00361 254 IQKYLGDGPKLVRELFRVAEENAPSIVFIDEIDAIGTKRYDA--TSGGEKEiqRTMLELLNQLDGFDSRGDVKVIMATNR 331
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882 630 PDIIDPALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKSPVSKDVDIRALAKYTQGFSGADITEICQRACKYAIRE 705
Cdd:PTZ00361 332 IESLDPALIRPGRIDRKIEFPNPDEKTKRRIFEIHTSKMTLAEDVDLEEFIMAKDELSGADIKAICTEAGLLALRE 407
RecA-like_Yta7-like cd19517
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ...
209-370 3.32e-58

ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410925 [Multi-domain]  Cd Length: 170  Bit Score: 195.81  E-value: 3.32e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGA-----FFFCINGPEIMSKLA 283
Cdd:cd19517    1 DIGGLSHYINQLKEMVFFPLLYPEVFAKFKITPPRGVLFHGPPGTGKTLMARALAAECSKggqkvSFFMRKGADCLSKWV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 284 GESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRR 363
Cdd:cd19517   81 GEAERQLRLLFEEAYRMQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGLDNRGQVVVIGATNRPDALDPALRR 160

                 ....*..
gi 645277882 364 FGRFDRE 370
Cdd:cd19517  161 PGRFDRE 167
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
208-438 7.38e-58

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 197.80  E-value: 7.38e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 208 DDVGGVRKQMAQIRELVElPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESE 287
Cdd:COG1223    2 DDVVGQEEAKKKLKLIIK-ELRRRENLRKFGLWPPRKILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSLIGSYLGETA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 288 SNLRKAFEEAeKNAPSIIFIDEIDSIAPKREKTH--GEVeRRIVSQLLTLMDGLKSraHVIVMGATNRPNSIDPALRRfg 365
Cdd:COG1223   81 RNLRKLFDFA-RRAPCVIFFDEFDAIAKDRGDQNdvGEV-KRVVNALLQELDGLPS--GSVVIAATNHPELLDSALWR-- 154
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 645277882 366 RFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLED 438
Cdd:COG1223  155 RFDEVIEFPLPDKEERKEILELNLKKFPLPFELDLKKLAKKLEGLSGADIEKVLKTALKKAILEDREKVTKED 227
pup_AAA TIGR03689
proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some ...
192-447 6.73e-57

proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some proteins are modified by ligation between an epsilon-amino group of a lysine side chain and the C-terminal carboxylate of the ubiquitin-like protein Pup. This modification leads to protein degradation by the archaeal-like proteasome found in the Actinobacteria. Members of this protein family belong to the AAA family of ATPases and tend to be clustered with the genes for Pup, the Pup ligase PafA, and structural components of the proteasome. This protein forms hexameric rings with ATPase activity. [Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 200312 [Multi-domain]  Cd Length: 512  Bit Score: 203.40  E-value: 6.73e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  192 EPVKREDEERL-----NEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANET 266
Cdd:TIGR03689 161 EAIPRTEVEDLvleevPDVTYADIGGLGSQIEQIRDAVELPFLHPELYREYGLKPPKGVLLYGPPGCGKTLIAKAVANSL 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  267 G----------AFFFCINGPEIMSKLAGESESNLRKAFEEAEKNA----PSIIFIDEIDSIApkreKTHG-----EVERR 327
Cdd:TIGR03689 241 AarigaegggkSYFLNIKGPELLNKYVGETERQIRLIFQRAREKAsegrPVIVFFDEMDSLF----RTRGsgvssDVETT 316
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  328 IVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHtknmkLAEDVDLEKIAKDT 407
Cdd:TIGR03689 317 VVPQLLAEIDGVESLDNVIVIGASNREDMIDPAILRPGRLDVKIRIERPDAEAAADIFAKY-----LTDDLPLPEDLAAH 391
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 645277882  408 HGYVGADLAALCTEA--ALQCIREKMDVIDLEDEEIDAEILN 447
Cdd:TIGR03689 392 DGDREATAAALIQRVvdALYARSEANRYVEVTYANGSTEVLY 433
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
205-373 1.43e-56

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 191.29  E-value: 1.43e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 205 VGYDDVGGVRKQMAQIRELVELpLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAG 284
Cdd:cd19501    1 VTFKDVAGCEEAKEELKEVVEF-LKNPEKFTKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 285 ESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREK----THGEVERRIvSQLLTLMDGLKSRAHVIVMGATNRPNSIDPA 360
Cdd:cd19501   80 VGASRVRDLFEQAKKNAPCIVFIDEIDAVGRKRGAglggGHDEREQTL-NQLLVEMDGFESNTGVIVIAATNRPDVLDPA 158
                        170
                 ....*....|...
gi 645277882 361 LRRFGRFDREIDI 373
Cdd:cd19501  159 LLRPGRFDRQVYV 171
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
482-647 3.21e-56

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 190.31  E-value: 3.21e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEA 561
Cdd:cd19518    1 DIGGMDSTLKELCELLIHPILPPEYFQHLGVEPPRGVLLHGPPGCGKTMLANAIAGELKVPFLKISATEIVSGVSGESEE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 562 NVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDaggAADRVLNQLLTEMDGMTAKKT----VFIIGATNRPDIIDPAL 637
Cdd:cd19518   81 KIRELFDQAISNAPCIVFIDEIDAITPKRESAQRE---MERRIVSQLLTCMDELNNEKTaggpVLVIGATNRPDSLDPAL 157
                        170
                 ....*....|
gi 645277882 638 LRPGRLDQLI 647
Cdd:cd19518  158 RRAGRFDREI 167
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
207-455 4.32e-56

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 204.11  E-value: 4.32e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 207 YDDVGGVRKQMAQIRELVELpLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGES 286
Cdd:PRK10733 151 FADVAGCDEAKEEVAELVEY-LREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVG 229
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 287 ESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKT----HGEVERRIvSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALR 362
Cdd:PRK10733 230 ASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGlgggHDEREQTL-NQMLVEMDGFEGNEGIIVIAATNRPDVLDPALL 308
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 363 RFGRFDREIDIGVPDEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDL-EDEEI 441
Cdd:PRK10733 309 RPGRFDRQVVVGLPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMvEFEKA 388
                        250
                 ....*....|....*....
gi 645277882 442 DAEIL-----NSMAVTNEH 455
Cdd:PRK10733 389 KDKIMmgaerRSMVMTEAQ 407
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
245-375 8.47e-55

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 184.72  E-value: 8.47e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  245 ILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEV 324
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDSE 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 645277882  325 ERRIVSQLLTLMDGLKSRAH-VIVMGATNRPNSIDPALRrfGRFDREIDIGV 375
Cdd:pfam00004  81 SRRVVNQLLTELDGFTSSNSkVIVIAATNRPDKLDPALL--GRFDRIIEFPL 130
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
219-373 3.38e-54

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 184.64  E-value: 3.38e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 219 QIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAE 298
Cdd:cd19528    4 ELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKAR 83
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 299 KNAPSIIFIDEIDSIAPKREKTHGE---VERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDI 373
Cdd:cd19528   84 AAAPCVLFFDELDSIAKARGGNIGDaggAADRVINQILTEMDGMNTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYI 161
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
518-651 3.51e-54

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 183.18  E-value: 3.51e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  518 VLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSvgdA 597
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSG---G 77
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 645277882  598 GGAADRVLNQLLTEMDGMTAKK-TVFIIGATNRPDIIDPALLrpGRLDQLIYIPL 651
Cdd:pfam00004  78 DSESRRVVNQLLTELDGFTSSNsKVIVIAATNRPDKLDPALL--GRFDRIIEFPL 130
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
210-373 1.08e-52

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 180.24  E-value: 1.08e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 210 VGGVRKQMAQIRELVELPLRHPQLFKSIgVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESN 289
Cdd:cd19509    1 IAGLDDAKEALKEAVILPSLRPDLFPGL-RGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 290 LRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGL--KSRAHVIVMGATNRPNSIDPALRRfgRF 367
Cdd:cd19509   80 VRALFALARELQPSIIFIDEIDSLLSERGSGEHEASRRVKTEFLVQMDGVlnKPEDRVLVLGATNRPWELDEAFLR--RF 157

                 ....*.
gi 645277882 368 DREIDI 373
Cdd:cd19509  158 EKRIYI 163
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
483-649 1.24e-52

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 180.24  E-value: 1.24e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 483 IGGLDNVKRELQETVQYPVEHPEKFeKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEAN 562
Cdd:cd19509    1 IAGLDDAKEALKEAVILPSLRPDLF-PGLRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 563 VREIFDKARGSAPCVLFFDELDSIATQRGSsvGDAGGAAdRVLNQLLTEMDGMTAK--KTVFIIGATNRPDIIDPALLRp 640
Cdd:cd19509   80 VRALFALARELQPSIIFIDEIDSLLSERGS--GEHEASR-RVKTEFLVQMDGVLNKpeDRVLVLGATNRPWELDEAFLR- 155

                 ....*....
gi 645277882 641 gRLDQLIYI 649
Cdd:cd19509  156 -RFEKRIYI 163
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
212-369 3.37e-52

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 178.84  E-value: 3.37e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 212 GVRKQ--MAQIRelvelPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESN 289
Cdd:cd19530    3 HVREEltMSILR-----PIKRPDIYKALGIDLPTGVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 290 LRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDR 369
Cdd:cd19530   78 VRQVFQRARASAPCVIFFDEVDALVPKRGDGGSWASERVVNQLLTEMDGLEERSNVFVIAATNRPDIIDPAMLRPGRLDK 157
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
220-371 1.10e-49

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 171.84  E-value: 1.10e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 220 IRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEK 299
Cdd:cd19526    5 LEETIEWPSKYPKIFASSPLRLRSGILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNKYIGASEQNVRDLFSRAQS 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 645277882 300 NAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREI 371
Cdd:cd19526   85 AKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQLDGVEGLDGVYVLAATSRPDLIDPALLRPGRLDKLV 156
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
219-369 4.05e-47

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 164.99  E-value: 4.05e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 219 QIRELVELPLRHPQLFKSiGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAE 298
Cdd:cd19527    4 EILDTIQLPLEHPELFSS-GLRKRSGILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEANVREVFQKAR 82
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 645277882 299 KNAPSIIFIDEIDSIAPKR--EKTHGEVERRIVSQLLTLMDGL-KSRAHVIVMGATNRPNSIDPALRRFGRFDR 369
Cdd:cd19527   83 DAKPCVIFFDELDSLAPSRgnSGDSGGVMDRVVSQLLAELDGMsSSGQDVFVIGATNRPDLLDPALLRPGRFDK 156
RecA-like_Yta7-like cd19517
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ...
482-648 5.44e-47

ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410925 [Multi-domain]  Cd Length: 170  Bit Score: 164.99  E-value: 5.44e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANEC-----QANFISVKGPELLTMWF 556
Cdd:cd19517    1 DIGGLSHYINQLKEMVFFPLLYPEVFAKFKITPPRGVLFHGPPGTGKTLMARALAAECskggqKVSFFMRKGADCLSKWV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 557 GESEANVREIFDKARGSAPCVLFFDELDSIATQRgSSVGDAGGAAdrVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPA 636
Cdd:cd19517   81 GEAERQLRLLFEEAYRMQPSIIFFDEIDGLAPVR-SSKQEQIHAS--IVSTLLALMDGLDNRGQVVVIGATNRPDALDPA 157
                        170
                 ....*....|..
gi 645277882 637 LLRPGRLDQLIY 648
Cdd:cd19517  158 LRRPGRFDREFY 169
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
209-363 8.74e-46

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 161.44  E-value: 8.74e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIGV-KPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESE 287
Cdd:cd19520    1 DIGGLDEVITELKELVILPLQRPELFDNSRLlQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGESQ 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 288 SNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAH--VIVMGATNRPNSIDPALRR 363
Cdd:cd19520   81 KLVAAVFSLASKLQPSIIFIDEIDSFLRQRSSTDHEATAMMKAEFMSLWDGLSTDGNcrVIVMGATNRPQDLDEAILR 158
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
205-373 4.21e-44

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 156.95  E-value: 4.21e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 205 VGYDDVGGVRKQMAQIRELVELPLRHPQLFKSiGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAG 284
Cdd:cd19521    4 VKWEDVAGLEGAKEALKEAVILPVKFPHLFTG-NRKPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 285 ESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGL-KSRAHVIVMGATNRPNSIDPALRR 363
Cdd:cd19521   83 ESEKLVKQLFAMARENKPSIIFIDEVDSLCGTRGEGESEASRRIKTELLVQMNGVgNDSQGVLVLGATNIPWQLDSAIRR 162
                        170
                 ....*....|
gi 645277882 364 fgRFDREIDI 373
Cdd:cd19521  163 --RFEKRIYI 170
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
482-639 5.11e-44

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 156.43  E-value: 5.11e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFGM-SPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESE 560
Cdd:cd19520    1 DIGGLDEVITELKELVILPLQRPELFDNSRLlQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGESQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 561 ANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDAGGaadRVLNQLLTEMDGMTAK--KTVFIIGATNRPDIIDPALL 638
Cdd:cd19520   81 KLVAAVFSLASKLQPSIIFIDEIDSFLRQRSSTDHEATA---MMKAEFMSLWDGLSTDgnCRVIVMGATNRPQDLDEAIL 157

                 .
gi 645277882 639 R 639
Cdd:cd19520  158 R 158
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
203-373 5.28e-44

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 157.07  E-value: 5.28e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 203 NEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGvKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKL 282
Cdd:cd19525   17 PPINWADIAGLEFAKKTIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKW 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 283 AGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLK--SRAHVIVMGATNRPNSIDPA 360
Cdd:cd19525   96 VGEGEKMVRALFSVARCKQPAVIFIDEIDSLLSQRGEGEHESSRRIKTEFLVQLDGATtsSEDRILVVGATNRPQEIDEA 175
                        170
                 ....*....|...
gi 645277882 361 LRRfgRFDREIDI 373
Cdd:cd19525  176 ARR--RLVKRLYI 186
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
476-649 1.39e-41

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 149.63  E-value: 1.39e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 476 PNVSWEDIGGLDNVKRELQETVQYPVEHPEKFeKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMW 555
Cdd:cd19521    2 PNVKWEDVAGLEGAKEALKEAVILPVKFPHLF-TGNRKPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKW 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 556 FGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDaggAADRVLNQLLTEMDGM-TAKKTVFIIGATNRPDIID 634
Cdd:cd19521   81 MGESEKLVKQLFAMARENKPSIIFIDEVDSLCGTRGEGESE---ASRRIKTELLVQMNGVgNDSQGVLVLGATNIPWQLD 157
                        170
                 ....*....|....*
gi 645277882 635 PALLRpgRLDQLIYI 649
Cdd:cd19521  158 SAIRR--RFEKRIYI 170
RecA-like_KTNA1 cd19522
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ...
482-649 2.51e-41

Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410930 [Multi-domain]  Cd Length: 170  Bit Score: 148.98  E-value: 2.51e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFgMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEA 561
Cdd:cd19522    1 DIADLEEAKKLLEEAVVLPMWMPEFFKGI-RRPWKGVLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTLTSKYRGESEK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 562 NVREIFDKARGSAPCVLFFDELDSIATQRGSSvgDAGGAADRVLNQLLTEMDGMT-------AKKTVFIIGATNRPDIID 634
Cdd:cd19522   80 LVRLLFEMARFYAPTTIFIDEIDSICSRRGTS--EEHEASRRVKSELLVQMDGVGgasenddPSKMVMVLAATNFPWDID 157
                        170
                 ....*....|....*
gi 645277882 635 PALLRpgRLDQLIYI 649
Cdd:cd19522  158 EALRR--RLEKRIYI 170
RecA-like_NSF-SEC18_r1-like cd19504
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ...
483-644 7.59e-41

first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410912 [Multi-domain]  Cd Length: 177  Bit Score: 147.64  E-value: 7.59e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 483 IGGLD----NVKRELQETVQYPvehPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFIS-VKGPELLTMWFG 557
Cdd:cd19504    2 IGGLDkefsDIFRRAFASRVFP---PEIVEQLGCKHVKGILLYGPPGTGKTLMARQIGKMLNAREPKiVNGPEILNKYVG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 558 ESEANVREIF------DKARG--SAPCVLFFDELDSIATQRGSSVGDAGgAADRVLNQLLTEMDGMTAKKTVFIIGATNR 629
Cdd:cd19504   79 ESEANIRKLFadaeeeQRRLGanSGLHIIIFDEIDAICKQRGSMAGSTG-VHDTVVNQLLSKIDGVEQLNNILVIGMTNR 157
                        170
                 ....*....|....*
gi 645277882 630 PDIIDPALLRPGRLD 644
Cdd:cd19504  158 KDLIDEALLRPGRLE 172
RecA-like_KTNA1 cd19522
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ...
209-373 4.25e-40

Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410930 [Multi-domain]  Cd Length: 170  Bit Score: 145.51  E-value: 4.25e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIGvKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESES 288
Cdd:cd19522    1 DIADLEEAKKLLEEAVVLPMWMPEFFKGIR-RPWKGVLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTLTSKYRGESEK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 289 NLRKAFEEAEKNAPSIIFIDEIDSIAPKR--EKTHgEVERRIVSQLLTLMDGL-------KSRAHVIVMGATNRPNSIDP 359
Cdd:cd19522   80 LVRLLFEMARFYAPTTIFIDEIDSICSRRgtSEEH-EASRRVKSELLVQMDGVggasendDPSKMVMVLAATNFPWDIDE 158
                        170
                 ....*....|....
gi 645277882 360 ALRRfgRFDREIDI 373
Cdd:cd19522  159 ALRR--RLEKRIYI 170
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
476-649 4.64e-39

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 143.20  E-value: 4.64e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 476 PNVSWEDIGGLDNVKRELQETVQYPVEHPEKFEKFgMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMW 555
Cdd:cd19525   17 PPINWADIAGLEFAKKTIKEIVVWPMLRPDIFTGL-RGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKW 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 556 FGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDaggAADRVLNQLLTEMDGMT--AKKTVFIIGATNRPDII 633
Cdd:cd19525   96 VGEGEKMVRALFSVARCKQPAVIFIDEIDSLLSQRGEGEHE---SSRRIKTEFLVQLDGATtsSEDRILVVGATNRPQEI 172
                        170
                 ....*....|....*.
gi 645277882 634 DPALLRpgRLDQLIYI 649
Cdd:cd19525  173 DEAARR--RLVKRLYI 186
RecA-like_spastin cd19524
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ...
209-364 3.66e-37

ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410932 [Multi-domain]  Cd Length: 164  Bit Score: 136.90  E-value: 3.66e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIGvKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESES 288
Cdd:cd19524    1 DIAGQDLAKQALQEMVILPSLRPELFTGLR-APARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEK 79
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 645277882 289 NLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRA--HVIVMGATNRPNSIDPA-LRRF 364
Cdd:cd19524   80 LVRALFAVARELQPSIIFIDEVDSLLSERSEGEHEASRRLKTEFLIEFDGVQSNGddRVLVMGATNRPQELDDAvLRRF 158
RecA-like_spastin cd19524
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ...
482-649 2.91e-35

ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410932 [Multi-domain]  Cd Length: 164  Bit Score: 131.51  E-value: 2.91e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFgMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEA 561
Cdd:cd19524    1 DIAGQDLAKQALQEMVILPSLRPELFTGL-RAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 562 NVREIFDKARGSAPCVLFFDELDSIATQRGSSVGDaggAADRVLNQLLTEMDGMTA--KKTVFIIGATNRPDIIDPALLR 639
Cdd:cd19524   80 LVRALFAVARELQPSIIFIDEVDSLLSERSEGEHE---ASRRLKTEFLIEFDGVQSngDDRVLVMGATNRPQELDDAVLR 156
                        170
                 ....*....|
gi 645277882 640 pgRLDQLIYI 649
Cdd:cd19524  157 --RFTKRVYV 164
RecA-like_NSF-SEC18_r1-like cd19504
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ...
210-373 4.17e-35

first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410912 [Multi-domain]  Cd Length: 177  Bit Score: 131.46  E-value: 4.17e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 210 VGGVRKQMAQI-RELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCI-NGPEIMSKLAGESE 287
Cdd:cd19504    2 IGGLDKEFSDIfRRAFASRVFPPEIVEQLGCKHVKGILLYGPPGTGKTLMARQIGKMLNAREPKIvNGPEILNKYVGESE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 288 SNLRKAFEEAE-----KNAPS---IIFIDEIDSIAPKREKTHGE--VERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSI 357
Cdd:cd19504   82 ANIRKLFADAEeeqrrLGANSglhIIIFDEIDAICKQRGSMAGStgVHDTVVNQLLSKIDGVEQLNNILVIGMTNRKDLI 161
                        170
                 ....*....|....*.
gi 645277882 358 DPALRRFGRFDREIDI 373
Cdd:cd19504  162 DEALLRPGRLEVQMEI 177
ycf46 CHL00195
Ycf46; Provisional
476-708 1.37e-34

Ycf46; Provisional


Pssm-ID: 177094 [Multi-domain]  Cd Length: 489  Bit Score: 138.61  E-value: 1.37e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 476 PNVSWEDIGGLDNVKRELQetvQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMW 555
Cdd:CHL00195 223 VNEKISDIGGLDNLKDWLK---KRSTSFSKQASNYGLPTPRGLLLVGIQGTGKSLTAKAIANDWQLPLLRLDVGKLFGGI 299
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 556 FGESEANVREIFDKARGSAPCVLFFDELDSiATQRGSSVGDaGGAADRVLNQLLTEMDgmTAKKTVFIIGATNRPDIIDP 635
Cdd:CHL00195 300 VGESESRMRQMIRIAEALSPCILWIDEIDK-AFSNSESKGD-SGTTNRVLATFITWLS--EKKSPVFVVATANNIDLLPL 375
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 645277882 636 ALLRPGRLDQLIYIPLPDEESRFQIFKSCLRKS-PVS-KDVDIRALAKYTQGFSGADITEICQRACKYAIRENIE 708
Cdd:CHL00195 376 EILRKGRFDEIFFLDLPSLEEREKIFKIHLQKFrPKSwKKYDIKKLSKLSNKFSGAEIEQSIIEAMYIAFYEKRE 450
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
211-374 1.53e-31

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 120.33  E-value: 1.53e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 211 GGVRKQMAQIRELVELPlrhpqlfksigvkPPKGILLYGPPGSGKTLIARAVANET---GAFFFCINGPEIMSKLAGESE 287
Cdd:cd00009    1 VGQEEAIEALREALELP-------------PPKNLLLYGPPGTGKTTLARAIANELfrpGAPFLYLNASDLLEGLVVAEL 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 288 ---SNLRKAFEEAEKNAPSIIFIDEIDSIAPkrekthgEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRF 364
Cdd:cd00009   68 fghFLVRLLFELAEKAKPGVLFIDEIDSLSR-------GAQNALLRVLETLNDLRIDRENVRVIGATNRPLLGDLDRALY 140
                        170
                 ....*....|
gi 645277882 365 GRFDREIDIG 374
Cdd:cd00009  141 DRLDIRIVIP 150
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
484-651 2.96e-30

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 116.86  E-value: 2.96e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 484 GGLDNVKRELQETVQYPvehpekfekfgmsPSKGVLFYGPPGCGKTLLAKAIANEC---QANFISVKGPELLTMWFGESE 560
Cdd:cd00009    1 VGQEEAIEALREALELP-------------PPKNLLLYGPPGTGKTTLARAIANELfrpGAPFLYLNASDLLEGLVVAEL 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 561 AN---VREIFDKARGSAPCVLFFDELDSIatqrgssvgdAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPAL 637
Cdd:cd00009   68 FGhflVRLLFELAEKAKPGVLFIDEIDSL----------SRGAQNALLRVLETLNDLRIDRENVRVIGATNRPLLGDLDR 137
                        170
                 ....*....|....
gi 645277882 638 LRPGRLDQLIYIPL 651
Cdd:cd00009  138 ALYDRLDIRIVIPL 151
RecA-like_Ycf46-like cd19507
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of ...
482-649 5.33e-30

ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of photosynthesis in cyanobacteria, especially in CO2 uptake and utilization. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410915 [Multi-domain]  Cd Length: 161  Bit Score: 116.31  E-value: 5.33e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQEtvQYPVEHPEKFeKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEA 561
Cdd:cd19507    1 DVGGLDNLKDWLKK--RKAAFSKQAS-AYGLPTPKGLLLVGIQGTGKSLTAKAIAGVWQLPLLRLDMGRLFGGLVGESES 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 562 NVREIFDKARGSAPCVLFFDELDSIATQRGSSvGDaGGAADRVLNQLLTEMDgmTAKKTVFIIGATNRPDIIDPALLRPG 641
Cdd:cd19507   78 RLRQMIQTAEAIAPCVLWIDEIEKGFSNADSK-GD-SGTSSRVLGTFLTWLQ--EKKKPVFVVATANNVQSLPPELLRKG 153

                 ....*...
gi 645277882 642 RLDQLIYI 649
Cdd:cd19507  154 RFDEIFFV 161
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
209-364 3.32e-29

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 114.21  E-value: 3.32e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVRKQMAQIRELVELPLRHPQLFKSIgVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESES 288
Cdd:cd19523    1 DIAGLGALKAAIKEEVLWPLLRPDAFSGL-LRLPRSILLFGPRGTGKTLLGRCLASQLGATFLRLRGSTLVAKWAGEGEK 79
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 289 NLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVErRIVSQLLTLMDGLKSRA--HVIVMGATNRPNSIDPALRRF 364
Cdd:cd19523   80 ILQASFLAARCRQPSVLFISDLDALLSSQDDEASPVG-RLQVELLAQLDGVLGSGedGVLVVCTTSKPEEIDESLRRY 156
RecA-like_Ycf46-like cd19507
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of ...
209-369 2.78e-25

ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of photosynthesis in cyanobacteria, especially in CO2 uptake and utilization. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410915 [Multi-domain]  Cd Length: 161  Bit Score: 102.83  E-value: 2.78e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 209 DVGGVR--KQMAQIRElvelPLRHPQLFKSiGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGES 286
Cdd:cd19507    1 DVGGLDnlKDWLKKRK----AAFSKQASAY-GLPTPKGLLLVGIQGTGKSLTAKAIAGVWQLPLLRLDMGRLFGGLVGES 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 287 ESNLRKAFEEAEKNAPSIIFIDEIDS-IAPKREKTHGEVERRIVSQLLTLMDGLKSRahVIVMGATNRPNSIDPALRRFG 365
Cdd:cd19507   76 ESRLRQMIQTAEAIAPCVLWIDEIEKgFSNADSKGDSGTSSRVLGTFLTWLQEKKKP--VFVVATANNVQSLPPELLRKG 153

                 ....
gi 645277882 366 RFDR 369
Cdd:cd19507  154 RFDE 157
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
482-639 1.43e-23

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 98.03  E-value: 1.43e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 482 DIGGLDNVKRELQETVQYPVEHPEKFEKFgMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEA 561
Cdd:cd19523    1 DIAGLGALKAAIKEEVLWPLLRPDAFSGL-LRLPRSILLFGPRGTGKTLLGRCLASQLGATFLRLRGSTLVAKWAGEGEK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 562 NVREIFDKARGSAPCVLFFDELDSIAtqrgSSVGDAGGAADRVLNQLLTEMDGM--TAKKTVFIIGATNRPDIIDPALLR 639
Cdd:cd19523   80 ILQASFLAARCRQPSVLFISDLDALL----SSQDDEASPVGRLQVELLAQLDGVlgSGEDGVLVVCTTSKPEEIDESLRR 155
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
241-377 3.15e-20

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 87.81  E-value: 3.15e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882   241 PPKGILLYGPPGSGKTLIARAVANE---TGAFFFCINGPEIMS--------------KLAGESESNLRKAFEEAEKNAPS 303
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARElgpPGGGVIYIDGEDILEevldqllliivggkKASGSGELRLRLALALARKLKPD 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 645277882   304 IIFIDEIDSIAPKREKthgevERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFgRFDREIDIGVPD 377
Cdd:smart00382  81 VLILDEITSLLDAEQE-----ALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRR-RFDRRIVLLLIL 148
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
514-653 3.40e-20

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 87.81  E-value: 3.40e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882   514 PSKGVLFYGPPGCGKTLLAKAIANECQANFISVK-----------------GPELLTMWFGESEANVREIFDKARGSAPC 576
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIyidgedileevldqlllIIVGGKKASGSGELRLRLALALARKLKPD 80
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 645277882   577 VLFFDELDSIAtqrgssvgDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPgRLDQLIYIPLPD 653
Cdd:smart00382  81 VLILDEITSLL--------DAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRR-RFDRRIVLLLIL 148
CDC48_N pfam02359
Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel ...
30-110 2.28e-19

Cell division protein 48 (CDC48), N-terminal domain; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases pfam00004 is a substrate 185-residue recognition domain.


Pssm-ID: 426738  Cd Length: 85  Bit Score: 83.01  E-value: 2.28e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882   30 RLVVDDAINDD--NSVVALHPDTMEKLQLFRGDTILIKVR*****ICIALADDTCEEPK--IRMNKVVRSNLRVRLGDVV 105
Cdd:pfam02359   1 RLRVAEAPDRDvgRGIARLNPEDMEELGLFPGDVVEIKGKRKT--VAIVWSAYPEDEGPgiIRMDGVTRKNAGVSIGDTV 78

                  ....*
gi 645277882  106 SVHQC 110
Cdd:pfam02359  79 TVRPA 83
ycf46 CHL00195
Ycf46; Provisional
238-430 4.03e-17

Ycf46; Provisional


Pssm-ID: 177094 [Multi-domain]  Cd Length: 489  Bit Score: 85.07  E-value: 4.03e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 238 GVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEID-SIAPK 316
Cdd:CHL00195 255 GLPTPRGLLLVGIQGTGKSLTAKAIANDWQLPLLRLDVGKLFGGIVGESESRMRQMIRIAEALSPCILWIDEIDkAFSNS 334
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 317 REKTHGEVERRIVSQLLTLMDGLKSRahVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEVGRLEVVRIHTKNM--KL 394
Cdd:CHL00195 335 ESKGDSGTTNRVLATFITWLSEKKSP--VFVVATANNIDLLPLEILRKGRFDEIFFLDLPSLEEREKIFKIHLQKFrpKS 412
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 645277882 395 AEDVDLEKIAKDTHGYVGADLAALCTEAALQCIREK 430
Cdd:CHL00195 413 WKKYDIKKLSKLSNKFSGAEIEQSIIEAMYIAFYEK 448
CDC48_N smart01073
Cell division protein 48 (CDC48) N-terminal domain; This domain has a double psi-beta barrel ...
31-110 1.18e-16

Cell division protein 48 (CDC48) N-terminal domain; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases is a substrate 185-residue recognition domain.


Pssm-ID: 215012 [Multi-domain]  Cd Length: 82  Bit Score: 75.34  E-value: 1.18e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882    31 LVVDDAINDD---NSVVALHPDTMEKLQLFRGDTILIKvr*****ICIALADDTCEEPK-IRMNKVVRSNLRVRLGDVVS 106
Cdd:smart01073   1 LRVAEAPSDEdvgRGIARLSPEDMDELGLFPGDYVLIT--GKRRTVAIVWPAYPEDPGGiIRIDGVQRKNAGVSIGDTVT 78

                   ....
gi 645277882   107 VHQC 110
Cdd:smart01073  79 VRKA 82
AAA_lid_3 pfam17862
AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ...
397-440 2.00e-14

AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.


Pssm-ID: 465537 [Multi-domain]  Cd Length: 45  Bit Score: 67.95  E-value: 2.00e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 645277882  397 DVDLEKIAKDTHGYVGADLAALCTEAALQCIREKMDVIDLEDEE 440
Cdd:pfam17862   1 DVDLEELAERTEGFSGADLEALCREAALAALRRGLEAVTQEDLE 44
RecA-like_Pch2-like cd19508
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as ...
518-649 5.46e-14

ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as Thyroid hormone receptor interactor 13 (TRIP13) and 16E1BP) is a key regulator of specific chromosomal events, like the control of G2/prophase processes such as DNA break formation and recombination, checkpoint signaling, and chromosome synapsis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion


Pssm-ID: 410916 [Multi-domain]  Cd Length: 199  Bit Score: 71.32  E-value: 5.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 518 VLFYGPPGCGKTLLAKAIANEC---------QANFISVKGPELLTMWFGESEANVREIFDK------ARGSAPCVLfFDE 582
Cdd:cd19508   55 VLLHGPPGTGKTSLCKALAQKLsirlssryrYGQLIEINSHSLFSKWFSESGKLVTKMFQKiqelidDKDALVFVL-IDE 133
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 583 LDSIATQR-GSSVGDAGGAADRVLNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLrpGRLDQLIYI 649
Cdd:cd19508  134 VESLAAARsASSSGTEPSDAIRVVNAVLTQIDRIKRYHNNVILLTSNLLEKIDVAFV--DRADIKQYI 199
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
516-649 1.42e-13

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 68.92  E-value: 1.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 516 KGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELltmwfGESEANVREIFDKARGSApcVLFFDELDS--IATQRGSS 593
Cdd:cd19510   24 RGYLLYGPPGTGKSSFIAALAGELDYDICDLNLSEV-----VLTDDRLNHLLNTAPKQS--IILLEDIDAafESREHNKK 96
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 645277882 594 VGDAGGAADRV-LNQLLTEMDGMTAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYI 649
Cdd:cd19510   97 NPSAYGGLSRVtFSGLLNALDGVASSEERIVFMTTNHIERLDPALIRPGRVDMKIYM 153
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
220-371 1.76e-13

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 68.53  E-value: 1.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 220 IRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINgpeimskLAGESESNLRKafEEAEK 299
Cdd:cd19510    1 IIDDLKDFIKNEDWYNDRGIPYRRGYLLYGPPGTGKSSFIAALAGELDYDICDLN-------LSEVVLTDDRL--NHLLN 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 300 NAP--SIIFIDEIDSIAPKREKT------HGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREI 371
Cdd:cd19510   72 TAPkqSIILLEDIDAAFESREHNkknpsaYGGLSRVTFSGLLNALDGVASSEERIVFMTTNHIERLDPALIRPGRVDMKI 151
RecA-like_Pch2-like cd19508
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as ...
245-361 2.09e-12

ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as Thyroid hormone receptor interactor 13 (TRIP13) and 16E1BP) is a key regulator of specific chromosomal events, like the control of G2/prophase processes such as DNA break formation and recombination, checkpoint signaling, and chromosome synapsis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion


Pssm-ID: 410916 [Multi-domain]  Cd Length: 199  Bit Score: 66.70  E-value: 2.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 245 ILLYGPPGSGKTLIARAVANE-----TGAFFFC----INGPEIMSKLAGESESNLRKAFEEAE-----KNAPSIIFIDEI 310
Cdd:cd19508   55 VLLHGPPGTGKTSLCKALAQKlsirlSSRYRYGqlieINSHSLFSKWFSESGKLVTKMFQKIQeliddKDALVFVLIDEV 134
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 645277882 311 DSIAPKREKTHGEVER----RIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPAL 361
Cdd:cd19508  135 ESLAAARSASSSGTEPsdaiRVVNAVLTQIDRIKRYHNNVILLTSNLLEKIDVAF 189
CDC48_2 smart01072
Cell division protein 48 (CDC48) domain 2; This domain has a double psi-beta barrel fold and ...
136-196 4.80e-12

Cell division protein 48 (CDC48) domain 2; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the C-terminus. The VAT-N domain found in AAA ATPases is a substrate 185-residue recognition domain.


Pssm-ID: 215011  Cd Length: 64  Bit Score: 61.46  E-value: 4.80e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 645277882   136 FDAYLKPYFLEayRPVRKGDLFLVRGGMRSVEFKVIETDPSEYCVVAPDTEIFCEGEPVKR 196
Cdd:smart01072   6 FAEYVKRKLLG--RPVTKGDTIVVPFLGKALPFVVVSTEPSGPVIVTDDTEIEILEKPVEE 64
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
245-310 5.71e-12

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 68.54  E-value: 5.71e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAFFFCINGpeIMSKLAgesesNLRKAFEEAEKNA----PSIIFIDEI 310
Cdd:COG2256   52 MILWGPPGTGKTTLARLIANATDAEFVALSA--VTSGVK-----DIREVIEEARERRaygrRTILFVDEI 114
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
245-310 6.47e-12

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 68.19  E-value: 6.47e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAFFFCINGPeimskLAGESEsnLRKAFEEAEKNAPS----IIFIDEI 310
Cdd:PRK13342  39 MILWGPPGTGKTTLARIIAGATDAPFEALSAV-----TSGVKD--LREVIEEARQRRSAgrrtILFIDEI 101
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
243-368 2.18e-11

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 62.54  E-value: 2.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 243 KGILLYGPPGSGKTLIARAVANETGAFFFCINGPEImSKLAGESESNLRKAFEEAEK-NAPSIIFIDEIDSIAPKREKTH 321
Cdd:cd19512   23 RNILFYGPPGTGKTLFAKKLALHSGMDYAIMTGGDV-APMGREGVTAIHKVFDWANTsRRGLLLFVDEADAFLRKRSTEK 101
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 645277882 322 GEVERRIVSQLLTLMDGLKSRAHVIVMgATNRPNSIDPALRrfGRFD 368
Cdd:cd19512  102 ISEDLRAALNAFLYRTGEQSNKFMLVL-ASNQPEQFDWAIN--DRID 145
RecA-like_IQCA1 cd19506
ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein ...
220-358 2.23e-10

ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein regulatory complex subunit 11, DRC11 and IQCA) is an ATPase subunit of the nexin-dynein regulatory complex (N-DRC). The 9 + 2 axoneme of most motile cilia and flagella consists of nine outer doublet microtubules arranged in a ring surrounding a central pair of two singlet microtubules. The N-DRC complex maintains alignment between outer doublet microtubules and limits microtubule sliding in motile axonemes. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410914 [Multi-domain]  Cd Length: 160  Bit Score: 59.85  E-value: 2.23e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 220 IRELVELPLRHPQLFKSIGVKPP--KGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGES--ESNLRKAFE 295
Cdd:cd19506    2 VRQLLTLYGILPLGSQAVHEKAPlvKSLLLAGPSGVGKKMLVHAICTETGANLFNLSPSNIAGKYPGKNglQMMLHLVLK 81
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 645277882 296 EAEKNAPSIIFIDEIDSIAPKR-EKTHGEVE-RRIVSQLLTLMDGLKSRAHVIVMGATNRPNSID 358
Cdd:cd19506   82 VARQLQPSVIWIGDAEKTFYKKvPKTEKQLDpKRLKKDLPKILKSLKPEDRVLIVGTTSRPFEAD 146
RecA-like_Ycf2 cd19505
ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; ...
509-649 2.37e-10

ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; however, its function remains unclear. The gene encoding YCF2 is the largest known plastid gene in angiosperms and has been used to predict phylogenetic relationships. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410913 [Multi-domain]  Cd Length: 161  Bit Score: 59.70  E-value: 2.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 509 KFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWF--------------GESEANVREIFDKARGSA 574
Cdd:cd19505    6 RLGLSPSKGILLIGSIETGRSYLIKSLAANSYVPLIRISLNKLLYNKPdfgnddwidgmlilKESLHRLNLQFELAKAMS 85
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 645277882 575 PCVLFFD---ELDS-IATQRGSSvgDAGGAADRVLNQLLTEMDGMTAKKTVfIIGATNRPDIIDPALLRPGRLDQLIYI 649
Cdd:cd19505   86 PCIIWIPnihELNVnRSTQNLEE--DPKLLLGLLLNYLSRDFEKSSTRNIL-VIASTHIPQKVDPALIAPNRLDTCINI 161
CDC48_2 pfam02933
Cell division protein 48 (CDC48), domain 2; This domain has a double psi-beta barrel fold and ...
138-195 9.35e-10

Cell division protein 48 (CDC48), domain 2; This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the C-terminus. The VAT-N domain found in AAA ATPases pfam00004 is a substrate 185-residue recognition domain.


Pssm-ID: 427063  Cd Length: 64  Bit Score: 55.32  E-value: 9.35e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882  138 AYLKPYFLEayRPVRKGDLFLVRGGMRSVEFKVIETDPSEYCVVAPDTEIFCEGEPVK 195
Cdd:pfam02933   8 AYVKRNLEG--RPVSKGDTIVVEFLGGAIPLVVVSTEPSGPVVVTETTEIEIGEKPVQ 63
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
513-647 1.03e-09

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 57.54  E-value: 1.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 513 SPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWfGESEANVREIFDKARGSAP-CVLFFDELDSIATQRG 591
Cdd:cd19512   20 GLYRNILFYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMG-REGVTAIHKVFDWANTSRRgLLLFVDEADAFLRKRS 98
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 645277882 592 SS-VGDAGGAAdrvLNQLLTEMdGMTAKKTVFIIgATNRPDIIDPALlrPGRLDQLI 647
Cdd:cd19512   99 TEkISEDLRAA---LNAFLYRT-GEQSNKFMLVL-ASNQPEQFDWAI--NDRIDEMV 148
AAA_lid_3 pfam17862
AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ...
673-712 2.40e-09

AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.


Pssm-ID: 465537 [Multi-domain]  Cd Length: 45  Bit Score: 53.31  E-value: 2.40e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 645277882  673 DVDIRALAKYTQGFSGADITEICQRACKYAIRENIE----KDIE 712
Cdd:pfam17862   1 DVDLEELAERTEGFSGADLEALCREAALAALRRGLEavtqEDLE 44
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
518-582 2.57e-09

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 60.07  E-value: 2.57e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882 518 VLFYGPPGCGKTLLAKAIANECQANFIS-------VKgpelltmwfgeseaNVREIFDKAR----GSAPCVLFFDE 582
Cdd:COG2256   52 MILWGPPGTGKTTLARLIANATDAEFVAlsavtsgVK--------------DIREVIEEARerraYGRRTILFVDE 113
T7SS_EccA TIGR03922
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ...
485-631 7.13e-09

type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 188437 [Multi-domain]  Cd Length: 557  Bit Score: 59.09  E-value: 7.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  485 GLDNVKRE---LQETVQYPVEHPEKfekfGMS---PSKGVLFYGPPGCGKTLLAKAIANE-C------QANFISVKGPEL 551
Cdd:TIGR03922 280 GLERVKRQvaaLKSSTAMALARAER----GLPvaqTSNHMLFAGPPGTGKTTIARVVAKIyCglgvlrKPLVREVSRADL 355
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  552 LTMWFGESEANVREIFDKARGSapcVLFFDELDSIaTQRGSSVGDAGGAAdrVLNQLLTEMDGMTAKKTVFIIGATNRPD 631
Cdd:TIGR03922 356 IGQYIGESEAKTNEIIDSALGG---VLFLDEAYTL-VETGYGQKDPFGLE--AIDTLLARMENDRDRLVVIGAGYRKDLD 429
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
518-582 1.26e-08

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 57.79  E-value: 1.26e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882 518 VLFYGPPGCGKTLLAKAIANECQANFI-------SVKgpelltmwfgeseaNVREIFDKARGSA----PCVLFFDE 582
Cdd:PRK13342  39 MILWGPPGTGKTTLARIIAGATDAPFEalsavtsGVK--------------DLREVIEEARQRRsagrRTILFIDE 100
T7SS_EccA TIGR03922
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ...
197-407 2.91e-08

type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 188437 [Multi-domain]  Cd Length: 557  Bit Score: 57.16  E-value: 2.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  197 EDEERLNE-VGyddVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPpKGILLYGPPGSGKTLIARAVANetgafFFC--- 272
Cdd:TIGR03922 270 EAEAELAEqIG---LERVKRQVAALKSSTAMALARAERGLPVAQTS-NHMLFAGPPGTGKTTIARVVAK-----IYCglg 340
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  273 -INGPEIM----SKLAGESESNLRKAFEEA-EKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVI 346
Cdd:TIGR03922 341 vLRKPLVRevsrADLIGQYIGESEAKTNEIiDSALGGVLFLDEAYTLVETGYGQKDPFGLEAIDTLLARMENDRDRLVVI 420
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882  347 VMG---ATNRPNSIDPALRRfgRFDREIDIG--VPDevgrlEVVRIhTKNMKLAEDVDLEKIAKDT 407
Cdd:TIGR03922 421 GAGyrkDLDKFLEVNEGLRS--RFTRVIEFPsySPD-----ELVEI-ARRMATERDSVLDDAAADA 478
PRK13341 PRK13341
AAA family ATPase;
246-310 8.44e-08

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 55.83  E-value: 8.44e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 246 LLYGPPGSGKTLIARAVANETGAFFFCINgpeimSKLAGESEsnLRKAFEEAEK-----NAPSIIFIDEI 310
Cdd:PRK13341  56 ILYGPPGVGKTTLARIIANHTRAHFSSLN-----AVLAGVKD--LRAEVDRAKErlerhGKRTILFIDEV 118
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
244-367 1.01e-07

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 51.52  E-value: 1.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  244 GILLYGPPGSGKTLIARAVANET-GAFFFCINGP------------EIMSKLAGESESNLRKAFEEAEknapsIIFIDEI 310
Cdd:pfam07728   1 GVLLVGPPGTGKTELAERLAAALsNRPVFYVQLTrdtteedlfgrrNIDPGGASWVDGPLVRAAREGE-----IAVLDEI 75
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882  311 DSIAPK-REKTHGEVERRIvsqlLTLMDG----LKSRAHVIVMGATNRP----NSIDPALRRfgRF 367
Cdd:pfam07728  76 NRANPDvLNSLLSLLDERR----LLLPDGgelvKAAPDGFRLIATMNPLdrglNELSPALRS--RF 135
RecA-like_Ycf2 cd19505
ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; ...
238-373 2.35e-07

ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; however, its function remains unclear. The gene encoding YCF2 is the largest known plastid gene in angiosperms and has been used to predict phylogenetic relationships. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410913 [Multi-domain]  Cd Length: 161  Bit Score: 51.22  E-value: 2.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 238 GVKPPKGILLYGPPGSGKTLIARAVANET--------------GAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPS 303
Cdd:cd19505    8 GLSPSKGILLIGSIETGRSYLIKSLAANSyvplirislnkllyNKPDFGNDDWIDGMLILKESLHRLNLQFELAKAMSPC 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 645277882 304 IIFIDEIDSIAPKREKTHGEVERRI-VSQLLTLMDGLKSRAHV---IVMGATNRPNSIDPALRRFGRFDREIDI 373
Cdd:cd19505   88 IIWIPNIHELNVNRSTQNLEEDPKLlLGLLLNYLSRDFEKSSTrniLVIASTHIPQKVDPALIAPNRLDTCINI 161
RecA-like_HslU cd19498
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease ...
242-338 2.65e-07

ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease HslVU. In HslVU, HslU ATPase serves to unfold and translocate protein substrate, and the HslV protease degrades the unfolded proteins. This RecA-like_HslU subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410906 [Multi-domain]  Cd Length: 183  Bit Score: 51.61  E-value: 2.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 242 PKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEI--MSKLAGESESNLRKAFEeaeknapSIIFIDEIDSIAPKREK 319
Cdd:cd19498   46 PKNILMIGPTGVGKTEIARRLAKLAGAPFIKVEATKFteVGYVGRDVESIIRDLVE-------GIVFIDEIDKIAKRGGS 118
                         90       100
                 ....*....|....*....|
gi 645277882 320 THGEVERRIVSQ-LLTLMDG 338
Cdd:cd19498  119 SGPDVSREGVQRdLLPIVEG 138
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
518-551 5.18e-07

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 50.19  E-value: 5.18e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 645277882  518 VLFYGPPGCGKTLLAKAIANECQANFISVKGPEL 551
Cdd:pfam05496  36 VLLYGPPGLGKTTLANIIANEMGVNIRITSGPAI 69
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
245-365 8.65e-07

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 51.67  E-value: 8.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSK--LAGeSESNLrkafeeaEKNapSIIFIDEIDSIAPKREkthg 322
Cdd:PRK00080  54 VLLYGPPGLGKTTLANIIANEMGVNIRITSGPALEKPgdLAA-ILTNL-------EEG--DVLFIDEIHRLSPVVE---- 119
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 323 EV------ERRIvsqllTLMDGLKSRAHVIVM--------GATNRPNSIDPALR-RFG 365
Cdd:PRK00080 120 EIlypameDFRL-----DIMIGKGPAARSIRLdlppftliGATTRAGLLTSPLRdRFG 172
44 PHA02544
clamp loader, small subunit; Provisional
226-385 1.07e-06

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 51.53  E-value: 1.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 226 LPLRHPQLFKSIgVKP---PKGILLYGPPGSGKTLIARAVANETGAFFFCINGpeimSKLAGESESNLRKAFEEA--EKN 300
Cdd:PHA02544  25 LPAADKETFKSI-VKKgriPNMLLHSPSPGTGKTTVAKALCNEVGAEVLFVNG----SDCRIDFVRNRLTRFASTvsLTG 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 301 APSIIFIDEIDsiapkREKTHgEVERrivsQLLTLMDGLKSRAHVIVmgATNRPNSIDPALRrfGRFdREIDIGVPDEVG 380
Cdd:PHA02544 100 GGKVIIIDEFD-----RLGLA-DAQR----HLRSFMEAYSKNCSFII--TANNKNGIIEPLR--SRC-RVIDFGVPTKEE 164

                 ....*
gi 645277882 381 RLEVV 385
Cdd:PHA02544 165 QIEMM 169
ruvB TIGR00635
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ...
245-409 1.24e-06

Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129721 [Multi-domain]  Cd Length: 305  Bit Score: 51.15  E-value: 1.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  245 ILLYGPPGSGKTLIARAVANETGAFFFCINGPEIM--SKLAGeSESNLRKAfeeaeknapSIIFIDEIDSIAPKREkthg 322
Cdd:TIGR00635  33 LLLYGPPGLGKTTLAHIIANEMGVNLKITSGPALEkpGDLAA-ILTNLEEG---------DVLFIDEIHRLSPAVE---- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  323 EVerrivsqLLTLMD----------GLKSR------AHVIVMGATNRPNSIDPALR-RFGrFDREIDIGVPDEVGRleVV 385
Cdd:TIGR00635  99 EL-------LYPAMEdfrldivigkGPSARsvrldlPPFTLVGATTRAGMLTSPLRdRFG-IILRLEFYTVEELAE--IV 168
                         170       180
                  ....*....|....*....|....*
gi 645277882  386 RIHTKNMKL-AEDVDLEKIAKDTHG 409
Cdd:TIGR00635 169 SRSAGLLNVeIEPEAALEIARRSRG 193
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
518-551 1.37e-06

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 51.28  E-value: 1.37e-06
                         10        20        30
                 ....*....|....*....|....*....|....
gi 645277882 518 VLFYGPPGCGKTLLAKAIANECQANFISVKGPEL 551
Cdd:PRK00080  54 VLLYGPPGLGKTTLANIIANEMGVNIRITSGPAL 87
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
245-365 2.34e-06

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 48.27  E-value: 2.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  245 ILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSK--LAGeSESNLRKAfeeaeknapSIIFIDEIDSIAPKREkthg 322
Cdd:pfam05496  36 VLLYGPPGLGKTTLANIIANEMGVNIRITSGPAIERPgdLAA-ILTNLEPG---------DVLFIDEIHRLNRAVE---- 101
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882  323 EV------ERRIVsqlLTLMDGLKSRAHVI------VMGATNRPNSIDPALR-RFG 365
Cdd:pfam05496 102 EIlypameDFRLD---IVIGKGPSARSIRLdlppftLVGATTRAGLLTSPLRdRFG 154
PRK04195 PRK04195
replication factor C large subunit; Provisional
240-438 3.85e-06

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 50.30  E-value: 3.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 240 KPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGP-----EIMSKLAGESeSNLRKAFEEAEKnapsIIFIDEIDSIa 314
Cdd:PRK04195  37 KPKKALLLYGPPGVGKTSLAHALANDYGWEVIELNASdqrtaDVIERVAGEA-ATSGSLFGARRK----LILLDEVDGI- 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 315 pkrektHGEVERRIVSQLLTLmdgLKSRAHVIVMGATN---------RPNSIDPALRRFGRfdREIdigvpdeVGRLEvv 385
Cdd:PRK04195 111 ------HGNEDRGGARAILEL---IKKAKQPIILTANDpydpslrelRNACLMIEFKRLST--RSI-------VPVLK-- 170
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882 386 RIHTKNMKLAEDVDLEKIAKDTHGyvgaDLaalctEAA---LQCIREKMDVIDLED 438
Cdd:PRK04195 171 RICRKEGIECDDEALKEIAERSGG----DL-----RSAindLQAIAEGYGKLTLED 217
AAA_2 pfam07724
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ...
242-315 1.01e-05

AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400187 [Multi-domain]  Cd Length: 168  Bit Score: 46.42  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  242 PKG-ILLYGPPGSGKTLIARAVANETGAF---FFCINGPEIM-----SKLAGESESNLRKA-----FEEAEKNAPSIIFI 307
Cdd:pfam07724   2 PIGsFLFLGPTGVGKTELAKALAELLFGDeraLIRIDMSEYMeehsvSRLIGAPPGYVGYEeggqlTEAVRRKPYSIVLI 81

                  ....*...
gi 645277882  308 DEIDSIAP 315
Cdd:pfam07724  82 DEIEKAHP 89
RecA-like_ClpB_Hsp104-like cd19499
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ...
240-368 1.65e-05

Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410907 [Multi-domain]  Cd Length: 178  Bit Score: 46.02  E-value: 1.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 240 KPPKGILLYGPPGSGKTLIARAVA---NETGAFFFCINGPEIMSKlagESESNLRKA-------------FEEAEKNAPS 303
Cdd:cd19499   39 RPIGSFLFLGPTGVGKTELAKALAellFGDEDNLIRIDMSEYMEK---HSVSRLIGAppgyvgyteggqlTEAVRRKPYS 115
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 645277882 304 IIFIDEIdsiapkrEKTHGEVeRRIVSQLL---TLMDGLKSRAH----VIVMGAtnrpNSIDPALrrFGRFD 368
Cdd:cd19499  116 VVLLDEI-------EKAHPDV-QNLLLQVLddgRLTDSHGRTVDfkntIIIMTS----NHFRPEF--LNRID 173
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
518-549 2.24e-05

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 47.38  E-value: 2.24e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 645277882 518 VLFYGPPGCGKTLLAKAIANECQANFISVKGP 549
Cdd:COG2255   57 VLLYGPPGLGKTTLAHIIANEMGVNIRITSGP 88
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
486-747 2.97e-05

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 46.51  E-value: 2.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 486 LDNVKRELQETVQYPVEHPekfekfgmspskGVLFYGPPGCGKTLLAKAIANE--------------CQANFISVKG-PE 550
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPH------------ALLLHGPPGIGKTTLALALARDllcenpeggkacgqCHSRLMAAGNhPD 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 551 LLTMwfgESEAN--------VREIFDKARGSAPC----VLFFDELDSIATqrgssvgdaggAADRVLNQLLTEmdgmTAK 618
Cdd:COG0470   69 LLEL---NPEEKsdqigidqIRELGEFLSLTPLEggrkVVIIDEADAMNE-----------AAANALLKTLEE----PPK 130
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 619 KTVFIIgATNRPDIIDPALL-RPgrldQLIYIPLPDEESrfqiFKSCLRKSPVSKDvDIRALAKYTQGFSGADITEICQR 697
Cdd:COG0470  131 NTPFIL-IANDPSRLLPTIRsRC----QVIRFRPPSEEE----ALAWLREEGVDED-ALEAILRLAGGDPRAAINLLQAL 200
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 645277882 698 ACKYAIRENIEKDIERERRRSENPEAMEEDVDDEVAEIrAAHFEESMKYA 747
Cdd:COG0470  201 AGRKELLEDLAALLSRDRALELLDALLKAEALELLDWL-LKWLLDNLPLE 249
PRK04195 PRK04195
replication factor C large subunit; Provisional
481-538 3.03e-05

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 47.22  E-value: 3.03e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 645277882 481 EDIGGLDNVKRELQETVqypvehpEKFEKfgMSPSKGVLFYGPPGCGKTLLAKAIANE 538
Cdd:PRK04195  14 SDVVGNEKAKEQLREWI-------ESWLK--GKPKKALLLYGPPGVGKTSLAHALAND 62
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
243-293 3.23e-05

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 47.27  E-value: 3.23e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882 243 KGILLYGPPGSGKTLIARAVANETGAF--FFCINGPEIMSKLAGESE---SNLRKA 293
Cdd:COG1224   65 KGILIVGPPGTGKTALAVAIARELGEDtpFVAISGSEIYSAELKKTEflmQALRKA 120
ruvB TIGR00635
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ...
479-551 4.28e-05

Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129721 [Multi-domain]  Cd Length: 305  Bit Score: 46.14  E-value: 4.28e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 645277882  479 SWEDIGGLDNVKRELQETVQYPVEHPEKFEKfgmspskgVLFYGPPGCGKTLLAKAIANECQANFISVKGPEL 551
Cdd:TIGR00635   2 LLAEFIGQEKVKEQLQLFIEAAKMRQEALDH--------LLLYGPPGLGKTTLAHIIANEMGVNLKITSGPAL 66
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
516-553 4.49e-05

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 45.54  E-value: 4.49e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 645277882 516 KGVLFYGPPGCGKTLLAKAIANE-CQAN----FISVkgPELLT 553
Cdd:COG1484  100 ENLILLGPPGTGKTHLAIALGHEaCRAGyrvrFTTA--PDLVN 140
MoxR COG0714
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ...
245-389 6.84e-05

MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 440478 [Multi-domain]  Cd Length: 292  Bit Score: 45.54  E-value: 6.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAFFFCING-PEIM-SKLAGESESNLRKAFEEAEKNaP---SIIFIDEIDSiAPkrEK 319
Cdd:COG0714   34 LLLEGVPGVGKTTLAKALARALGLPFIRIQFtPDLLpSDILGTYIYDQQTGEFEFRPG-PlfaNVLLADEINR-AP--PK 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 320 THgeverrivSQLLTLM-------DG----LKSRAHVIvmgATNrpNSID--------PALRRfgRFDREIDIGVPDEVG 380
Cdd:COG0714  110 TQ--------SALLEAMeerqvtiPGgtykLPEPFLVI---ATQ--NPIEqegtyplpEAQLD--RFLLKLYIGYPDAEE 174

                 ....*....
gi 645277882 381 RLEVVRIHT 389
Cdd:COG0714  175 EREILRRHT 183
TIP49 pfam06068
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ...
243-293 1.32e-04

TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.


Pssm-ID: 399217 [Multi-domain]  Cd Length: 347  Bit Score: 44.99  E-value: 1.32e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 645277882  243 KGILLYGPPGSGKTLIARAVANETGAF--FFCINGPEIMSKLAGESES---NLRKA 293
Cdd:pfam06068  51 RAVLIAGPPGTGKTALAIAISKELGEDtpFTSISGSEVYSLEMKKTEAltqAFRKA 106
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
218-371 1.83e-04

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 44.45  E-value: 1.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 218 AQIRELVELpLRhPQLFKSigvkPPKGILLYGPPGSGKTLIARAV-------ANETGAFFFC--INGPE------IMSKL 282
Cdd:COG1474   33 EEIEELASA-LR-PALRGE----RPSNVLIYGPTGTGKTAVAKYVleeleeeAEERGVDVRVvyVNCRQastryrVLSRI 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 283 A------------GESESNLRKAFEEA--EKNAPSIIFIDEIDSIapkrEKTHGEverRIVSQLLTLMDGLKSrAHVIVM 348
Cdd:COG1474  107 LeelgsgedipstGLSTDELFDRLYEAldERDGVLVVVLDEIDYL----VDDEGD---DLLYQLLRANEELEG-ARVGVI 178
                        170       180
                 ....*....|....*....|....*..
gi 645277882 349 GATNRPN---SIDPALR-RFGrfDREI 371
Cdd:COG1474  179 GISNDLEfleNLDPRVKsSLG--EEEI 203
AAA_22 pfam13401
AAA domain;
245-349 2.27e-04

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 41.94  E-value: 2.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  245 ILLYGPPGSGKTLIARAVAN---ETGAFFFCINGP------EIMSKLAGE---------SESNLRKAFEEA--EKNAPSI 304
Cdd:pfam13401   8 LVLTGESGTGKTTLLRRLLEqlpEVRDSVVFVDLPsgtspkDLLRALLRAlglplsgrlSKEELLAALQQLllALAVAVV 87
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 645277882  305 IFIDEIDSIAPKrekthgeverrIVSQLLTLMDGLKSRAHVIVMG 349
Cdd:pfam13401  88 LIIDEAQHLSLE-----------ALEELRDLLNLSSKLLQLILVG 121
PRK13341 PRK13341
AAA family ATPase;
519-546 2.33e-04

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 44.66  E-value: 2.33e-04
                         10        20
                 ....*....|....*....|....*...
gi 645277882 519 LFYGPPGCGKTLLAKAIANECQANFISV 546
Cdd:PRK13341  56 ILYGPPGVGKTTLARIIANHTRAHFSSL 83
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
245-310 2.62e-04

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 43.92  E-value: 2.62e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAFFFCINGPEImSK---LAGeSESNLrkafeeaEKNapSIIFIDEI 310
Cdd:COG2255   57 VLLYGPPGLGKTTLAHIIANEMGVNIRITSGPAI-EKpgdLAA-ILTNL-------EEG--DVLFIDEI 114
PRK08116 PRK08116
hypothetical protein; Validated
515-547 3.93e-04

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 43.09  E-value: 3.93e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 645277882 515 SKGVLFYGPPGCGKTLLAKAIANECQANFISVK 547
Cdd:PRK08116 114 NVGLLLWGSVGTGKTYLAACIANELIEKGVPVI 146
Vps4_C pfam09336
Vps4 C terminal oligomerization domain; This domain is found at the C terminal of ATPase ...
721-764 3.95e-04

Vps4 C terminal oligomerization domain; This domain is found at the C terminal of ATPase proteins involved in vacuolar sorting. It forms an alpha helix structure and is required for oligomerization.


Pssm-ID: 462762 [Multi-domain]  Cd Length: 61  Bit Score: 39.02  E-value: 3.95e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 645277882  721 PEAME---EDVD-DEVAE--IRAAHFEESMKYARRSVSDADIRKYQAFAQ 764
Cdd:pfam09336   9 PGAIEmtwMDIPsDKLLEppVTMKDFLKALKSSRPTVSKEDLEKYEEFTK 58
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
214-348 4.13e-04

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 41.72  E-value: 4.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  214 RKQMAQIRELVElPLRHPQlfksigvkpPKGILLYGPPGSGKTLIARAV---ANETGAFFFCINGPEIMSKLA---GESE 287
Cdd:pfam13191   6 EEELEQLLDALD-RVRSGR---------PPSVLLTGEAGTGKTTLLRELlraLERDGGYFLRGKCDENLPYSPlleALTR 75
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 645277882  288 SNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVM 348
Cdd:pfam13191  76 EGLLRQLLDELESSLLEAWRAALLEALAPVPELPGDLAERLLDLLLRLLDLLARGERPLVL 136
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
517-639 7.61e-04

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 40.35  E-value: 7.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  517 GVLFYGPPGCGKTLLAKAIANE-CQANFISVKGPELLTmwfgesEANVREIFDKARGSA-------------PCVLFFDE 582
Cdd:pfam07728   1 GVLLVGPPGTGKTELAERLAAAlSNRPVFYVQLTRDTT------EEDLFGRRNIDPGGAswvdgplvraareGEIAVLDE 74
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  583 LDSIatqrGSSVGDaggaadrVLNQLLTE-----MDG---MTAKKTVF-IIGATNRPDI----IDPALLR 639
Cdd:pfam07728  75 INRA----NPDVLN-------SLLSLLDErrlllPDGgelVKAAPDGFrLIATMNPLDRglneLSPALRS 133
AAA_2 pfam07724
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ...
518-587 9.12e-04

AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400187 [Multi-domain]  Cd Length: 168  Bit Score: 40.64  E-value: 9.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  518 VLFYGPPGCGKTLLAKAIANE---CQANFISVKGPELL-----TMWFGESEANVR-----EIFDKARGSAPCVLFFDELD 584
Cdd:pfam07724   6 FLFLGPTGVGKTELAKALAELlfgDERALIRIDMSEYMeehsvSRLIGAPPGYVGyeeggQLTEAVRRKPYSIVLIDEIE 85

                  ...
gi 645277882  585 SIA 587
Cdd:pfam07724  86 KAH 88
PRK08116 PRK08116
hypothetical protein; Validated
244-310 1.07e-03

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 41.54  E-value: 1.07e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 645277882 244 GILLYGPPGSGKTLIARAVAN---ETGAFFFCINGPEIMSKLAgeSESNLRKAFEEAE-----KNAPSIIfIDEI 310
Cdd:PRK08116 116 GLLLWGSVGTGKTYLAACIANeliEKGVPVIFVNFPQLLNRIK--STYKSSGKEDENEiirslVNADLLI-LDDL 187
PRK06835 PRK06835
DNA replication protein DnaC; Validated
487-538 1.10e-03

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 41.81  E-value: 1.10e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 645277882 487 DNVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANE 538
Cdd:PRK06835 155 DDEPLSPRKNMEKILEKCKNFIENFDKNNENLLFYGNTGTGKTFLSNCIAKE 206
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
518-538 1.32e-03

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 38.74  E-value: 1.32e-03
                          10        20
                  ....*....|....*....|.
gi 645277882  518 VLFYGPPGCGKTLLAKAIANE 538
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLARA 21
RecA-like_Lon cd19500
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ...
245-314 2.14e-03

lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410908 [Multi-domain]  Cd Length: 182  Bit Score: 39.85  E-value: 2.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAFFFCINgpeimskLAG-ESESNLR---------------KAFEEAEKNAPsIIFID 308
Cdd:cd19500   40 LCLVGPPGVGKTSLGKSIARALGRKFVRIS-------LGGvRDEAEIRghrrtyvgampgriiQALKKAGTNNP-VFLLD 111

                 ....*.
gi 645277882 309 EIDSIA 314
Cdd:cd19500  112 EIDKIG 117
RecA-like_superfamily cd01120
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ...
245-358 2.28e-03

RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410865 [Multi-domain]  Cd Length: 119  Bit Score: 38.64  E-value: 2.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAF---FFCINGPEIMsklagesesnLRKAFEEAEKNAPSIIFIDEIDSIAPKREkth 321
Cdd:cd01120    1 ILITGPPGSGKTTLLLQFAEQALLSdepVIFISFLDTI----------LEAIEDLIEEKKLDIIIIDSLSSLARASQ--- 67
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 645277882 322 GEVERRIVSQLLTLMDGLKsRAHVIVMGATNRPNSID 358
Cdd:cd01120   68 GDRSSELLEDLAKLLRAAR-NTGITVIATIHSDKFDI 103
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
516-561 2.74e-03

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 41.11  E-value: 2.74e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 645277882 516 KGVLFYGPPGCGKTLLAKAIANECQAN--FISVKGPELLTMWFGESEA 561
Cdd:COG1224   65 KGILIVGPPGTGKTALAVAIARELGEDtpFVAISGSEIYSAELKKTEF 112
McrB COG1401
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ...
293-542 3.12e-03

5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];


Pssm-ID: 441011 [Multi-domain]  Cd Length: 477  Bit Score: 40.91  E-value: 3.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 293 AFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREID 372
Cdd:COG1401    3 RPVLEFKFLIVGLRLKPLESEDAVRELGIRADDLRGAAELATRLAERLSEELLRADRAARATELVEELSAALEVVVLLLD 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 373 IGvpdEVGRLEVVRIHTKNMKLAEDVDLEKIAKDTHGYVGADLAALCTEAALQC--IREKMDVIDLEDEEIDAEILNSMA 450
Cdd:COG1401   83 LE---KVELNEKLALSEAAVAIEELYELEADSEIEAVGLLLELAERSDALEALEraRLLLELADLEERAALETEVLEALE 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 451 VTNEHFKTALGTSNPSALRETVVEVPNVSWEDIGGLDNVKRELQETVqypveHPEKFEKF--GMSPSKGVLFYGPPGCGK 528
Cdd:COG1401  160 AELEELLAAPEDLSADALAAELSAAEELYSEDLESEDDYLKDLLREK-----FEETLEAFlaALKTKKNVILAGPPGTGK 234
                        250
                 ....*....|....
gi 645277882 529 TLLAKAIANECQAN 542
Cdd:COG1401  235 TYLARRLAEALGGE 248
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
518-552 3.19e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 40.15  E-value: 3.19e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 645277882 518 VLFYGPPGCGKTLLAKAIANE-CQAN----FISVkgPELL 552
Cdd:NF038214  93 VLLLGPPGTGKTHLAIALGYAaCRQGyrvrFTTA--ADLV 130
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
518-535 4.57e-03

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 39.06  E-value: 4.57e-03
                          10
                  ....*....|....*...
gi 645277882  518 VLFYGPPGCGKTLLAKAI 535
Cdd:pfam01078  25 LLMIGPPGSGKTMLAKRL 42
Parvo_NS1 pfam01057
Parvovirus non-structural protein NS1; This family also contains the NS2 protein. Parvoviruses ...
518-537 4.81e-03

Parvovirus non-structural protein NS1; This family also contains the NS2 protein. Parvoviruses encode two non-structural proteins, NS1 and NS2. The mRNA for NS2 contains the coding sequence for the first 87 amino acids of NS1, then by an alternative splicing mechanism mRNA from a different reading frame, encoding the last 78 amino acids, makes up the full length of the NS2 mRNA. NS1, is the major non-structural protein. It is essential for DNA replication. It is an 83-kDa nuclear phosphoprotein. It has DNA helicase and ATPase activity.


Pssm-ID: 426020  Cd Length: 271  Bit Score: 39.60  E-value: 4.81e-03
                          10        20
                  ....*....|....*....|
gi 645277882  518 VLFYGPPGCGKTLLAKAIAN 537
Cdd:pfam01057 116 VWFYGPASTGKTNLAQAIAH 135
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
201-353 5.26e-03

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 39.38  E-value: 5.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 201 RLNEVGYDDVGGVRKqmAQIRELVELPlrhpqlFksigVKPPKGILLYGPPGSGKTLIARAVANE------TGAFFFCin 274
Cdd:COG1484   70 TLEDFDFDAQPGLDR--RQILELATLD------F----IERGENLILLGPPGTGKTHLAIALGHEacragyRVRFTTA-- 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 275 gPEIMSKLA-GESESNLRKAFEEAEKnaPSIIFIDEIDSIAPKREKTH--GEV-----ERR---IVSQL----------- 332
Cdd:COG1484  136 -PDLVNELKeARADGRLERLLKRLAK--VDLLILDELGYLPLDAEGAEllFELisdryERRstiITSNLpfsewgevfgd 212
                        170       180
                 ....*....|....*....|....*
gi 645277882 333 --LT--LMDGLKSRAHVIVMGATNR 353
Cdd:COG1484  213 ptLAtaILDRLVHHAHIIELKGESY 237
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
245-285 5.62e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 38.36  E-value: 5.62e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 645277882 245 ILLYGPPGSGKTLIARAVANETGAFFFCINgpEIMSKLAGE 285
Cdd:COG0645    2 ILVCGLPGSGKSTLARALAERLGAVRLRSD--VVRKRLFGA 40
RecA-like_HslU cd19498
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease ...
516-597 5.71e-03

ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease HslVU. In HslVU, HslU ATPase serves to unfold and translocate protein substrate, and the HslV protease degrades the unfolded proteins. This RecA-like_HslU subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410906 [Multi-domain]  Cd Length: 183  Bit Score: 38.51  E-value: 5.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 516 KGVLFYGPPGCGKTLLAKAIANECQANFISVKGPElltmwFGESEANVREIFDKARGSAPCVLFFDELDSIATQRGSSVG 595
Cdd:cd19498   47 KNILMIGPTGVGKTEIARRLAKLAGAPFIKVEATK-----FTEVGYVGRDVESIIRDLVEGIVFIDEIDKIAKRGGSSGP 121

                 ..
gi 645277882 596 DA 597
Cdd:cd19498  122 DV 123
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
249-328 6.15e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 38.65  E-value: 6.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882 249 GPPGSGKTLIARAVANETGafFFCINGpEIMSKLAGESESNLrKAFEEAEKNAPSIIFIDEidsiaPKREKTHGEVERRI 328
Cdd:COG1102    7 REPGSGGTTIAKRLAEKLG--LPLYDG-EILREAAKERGLSE-EEFEKLDEKAPSLLYRDT-----AEEDEIDRALDKVI 77
hslU PRK05201
ATP-dependent protease ATPase subunit HslU;
291-326 6.38e-03

ATP-dependent protease ATPase subunit HslU;


Pssm-ID: 235364 [Multi-domain]  Cd Length: 443  Bit Score: 39.68  E-value: 6.38e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 645277882 291 RKAFEEAEKNApsIIFIDEIDSIAPKREKTHGEVER 326
Cdd:PRK05201 241 QEAIERVEQNG--IVFIDEIDKIAARGGSSGPDVSR 274
TIGR02928 TIGR02928
orc1/cdc6 family replication initiation protein; Members of this protein family are found ...
241-343 7.03e-03

orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274354 [Multi-domain]  Cd Length: 365  Bit Score: 39.54  E-value: 7.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 645277882  241 PPKGILLYGPPGSGKTLIARAVANE-------TGAFFF-----C--INGP-EIMSKLA---GESESN-----------LR 291
Cdd:TIGR02928  39 RPSNVFIYGKTGTGKTAVTKYVMKEleeaaedRDVRVVtvyvnCqiLDTLyQVLVELAnqlRGSGEEvpttglstsevFR 118
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 645277882  292 KAFEEAEKNAPSIIFI-DEIDSIAPK---------REKTHGEVER-RI----VSQLLTLMDGLKSRA 343
Cdd:TIGR02928 119 RLYKELNERGDSLIIVlDEIDYLVGDdddllyqlsRARSNGDLDNaKVgvigISNDLKFRENLDPRV 185
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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