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Conserved domains on  [gi|627808641|ref|XP_007677668|]
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uncharacterized protein BAUCODRAFT_110130 [Baudoinia panamericana UAMH 10762]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 38-491 3.21e-151

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 438.81  E-value: 3.21e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   38 YDVVCIGGGPAGLSFASALKAHSATRALKVALIDAQDITTSRTGN---DGDAYSNRCSSLTPASSRFLRKIGAWDHINTG 114
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKLKSRNyekPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  115 RVQPYHAMDVWDGVSGSKIHFDPRRyeaGSDYgvVATMCENGNLTAALLQRLQALTtgdagaGSVCDILDKTKVESIELg 194
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDN---GKED--MACIIENDNIQNSLYNRLQEYN------GDNVKILNPARLISVTI- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  195 pqpETEETVDLSQWPIVMTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaADEVRTAFQRF 273
Cdd:TIGR01989 149 ---PSKYPNDNSNWVHITLSDGQvLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEE---ATENDVAWQRF 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  274 LPTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAFRLMPVDVNFMLSPDMAVTP-SEELRWREPaTSPS 352
Cdd:TIGR01989 223 LPTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPYSYLLDYAMEKlNEDIGFRTE-GSKS 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  353 STGLPstfPWITGVQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIG 432
Cdd:TIGR01989 302 CFQVP---PRVIGVVDKSRAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIG 378

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 627808641  433 SSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALM 491
Cdd:TIGR01989 379 SISSLKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 38-491 3.21e-151

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 438.81  E-value: 3.21e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   38 YDVVCIGGGPAGLSFASALKAHSATRALKVALIDAQDITTSRTGN---DGDAYSNRCSSLTPASSRFLRKIGAWDHINTG 114
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKLKSRNyekPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  115 RVQPYHAMDVWDGVSGSKIHFDPRRyeaGSDYgvVATMCENGNLTAALLQRLQALTtgdagaGSVCDILDKTKVESIELg 194
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDN---GKED--MACIIENDNIQNSLYNRLQEYN------GDNVKILNPARLISVTI- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  195 pqpETEETVDLSQWPIVMTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaADEVRTAFQRF 273
Cdd:TIGR01989 149 ---PSKYPNDNSNWVHITLSDGQvLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEE---ATENDVAWQRF 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  274 LPTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAFRLMPVDVNFMLSPDMAVTP-SEELRWREPaTSPS 352
Cdd:TIGR01989 223 LPTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPYSYLLDYAMEKlNEDIGFRTE-GSKS 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  353 STGLPstfPWITGVQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIG 432
Cdd:TIGR01989 302 CFQVP---PRVIGVVDKSRAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIG 378

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 627808641  433 SSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALM 491
Cdd:TIGR01989 379 SISSLKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
PRK07364 PRK07364
FAD-dependent hydroxylase;
25-498 3.08e-82

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 261.11  E-value: 3.08e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  25 SSAVSVTPGKPDI-YDVVCIGGGPAGLSFASALKAhsatRALKVALIDAQdiTTSRTGNDGDAYSnrcssLTPASSRFLR 103
Cdd:PRK07364   5 AATSPTLPSTRSLtYDVAIVGGGIVGLTLAAALKD----SGLRIALIEAQ--PAEAAAAKGQAYA-----LSLLSARIFE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 104 KIGAWDHInTGRVQPYHAMDVWDGVSGSKIHFDPRryEAGSDY-GVVAtmcENgnltAALLQRLQALTTGDAGAGSVCdi 182
Cdd:PRK07364  74 GIGVWEKI-LPQIGKFRQIRLSDADYPGVVKFQPT--DLGTEAlGYVG---EH----QVLLEALQEFLQSCPNITWLC-- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 183 ldKTKVESIELGpqpETEETVDLSQWPIvmtsQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEqtfa 262
Cdd:PRK07364 142 --PAEVVSVEYQ---QDAATVTLEIEGK----QQTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHE---- 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 263 ADEVRTAFQRFLPTGPIALLPLPGNKASLVWsTSPQHAAK-LKQLPPNDFVAmvsaafrlmpvdvnfmlspdmavtpseE 341
Cdd:PRK07364 209 APHNDIAYERFWPSGPFAILPLPGNRCQIVW-TAPHAQAKaLLALPEAEFLA---------------------------E 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 342 LRWRepatspsstglpstfpwiTGVQEGSIAS------FPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAE 415
Cdd:PRK07364 261 LQQR------------------YGDQLGKLELlgdrflFPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAA 322

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 416 ALANQITYGMEHGMDIGSSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAA 495
Cdd:PRK07364 323 ALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLKRLALRLMT 402


                 ...
gi 627808641 496 GAK 498
Cdd:PRK07364 403 GLK 405
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 38-491 1.62e-53

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 183.22  E-value: 1.62e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALKAHSatraLKVALIDAQdittSRTGNDGdaysnRCSSLTPASSRFLRKIGAWDHInTGRVQ 117
Cdd:COG0654    4 TDVLIVGGGPAGLALALALARAG----IRVTVVERA----PPPRPDG-----RGIALSPRSLELLRRLGLWDRL-LARGA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDGVSGSKI-HFDPRryEAGSDYGVvatMCENGNLTAALLQRLQALTtgdagagsvCDILDKTKVESIElgpQ 196
Cdd:COG0654   70 PIRGIRVRDGSDGRVLaRFDAA--ETGLPAGL---VVPRADLERALLEAARALG---------VELRFGTEVTGLE---Q 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 197 PETEETVDLSqwpivmtSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELeqtfaadEVRTAFQRFLPt 276
Cdd:COG0654  133 DADGVTVTLA-------DGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVRT-------ELRARLAAAGP- 197

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 277 gpiallplpgnkaslvwstspqhaaklkqlppnDFVAMVSAafrlmpvdvnfmlspdmavtpseelrwrepatspsstgl 356
Cdd:COG0654  198 ---------------------------------RLGELLEL--------------------------------------- 205

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 357 pstfpwitgvqeGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITygmEHGMDIGSSWC 436
Cdd:COG0654  206 ------------SPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLA---AALRGRDDEAA 270

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 627808641 437 LDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALM 491
Cdd:COG0654  271 LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKGGGL 325
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 38-444 2.20e-19

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 89.31  E-value: 2.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   38 YDVVCIGGGPAGLSFASALkahsATRALKVALIDAQDiTTSRTGndgdaysnRCSSLTPASSRFLRKIGAWDHI-NTGRV 116
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLL----ARAGVRVVLVERHA-TTSVLP--------RAHGLNQRTMELLRQAGLEDRIlAEGVP 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  117 QPYHAMDVWDGVSGSKIHFDpRRYEAGSDYGVVatmcengNLTAALLQRLQALTtgdagagsvCDILDKTKVESIElgpQ 196
Cdd:pfam01494  69 HEGMGLAFYNTRRRADLDFL-TSPPRVTVYPQT-------ELEPILVEHAEARG---------AQVRFGTEVLSLE---Q 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  197 PETEETVDLSQwpiVMTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTFAADEVRTAFqrflp 275
Cdd:pfam01494 129 DGDGVTAVVRD---RRDGEEYtVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDLSDPVERAFV----- 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  276 tgpIALLPLPGNKASLVwstspqhaaklkqlppndfVAMVSAAFRLMPVDVNFMLSPDmavTPSEELRWREPATS-PSST 354
Cdd:pfam01494 201 ---HYLIYAPHSRGFMV-------------------GPWRSAGRERYYVQVPWDEEVE---ERPEEFTDEELKQRlRSIV 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  355 GLPSTFPWITGVQegsiaSFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQIT--YGMEhgmdiG 432
Cdd:pfam01494 256 GIDLALVEILWKS-----IWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLAavLRGQ-----A 325

                         410
                  ....*....|..
gi 627808641  433 SSWCLDGYNSER 444
Cdd:pfam01494 326 GESLLDTYSAER 337
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 38-491 3.21e-151

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 438.81  E-value: 3.21e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   38 YDVVCIGGGPAGLSFASALKAHSATRALKVALIDAQDITTSRTGN---DGDAYSNRCSSLTPASSRFLRKIGAWDHINTG 114
Cdd:TIGR01989   1 FDVVIVGGGPVGLALAAALGNNPLTKDLKVLLLDAVDNPKLKSRNyekPDGPYSNRVSSITPASISFFKKIGAWDHIQSD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  115 RVQPYHAMDVWDGVSGSKIHFDPRRyeaGSDYgvVATMCENGNLTAALLQRLQALTtgdagaGSVCDILDKTKVESIELg 194
Cdd:TIGR01989  81 RIQPFGRMQVWDGCSLALIRFDRDN---GKED--MACIIENDNIQNSLYNRLQEYN------GDNVKILNPARLISVTI- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  195 pqpETEETVDLSQWPIVMTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaADEVRTAFQRF 273
Cdd:TIGR01989 149 ---PSKYPNDNSNWVHITLSDGQvLYTKLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEE---ATENDVAWQRF 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  274 LPTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAFRLMPVDVNFMLSPDMAVTP-SEELRWREPaTSPS 352
Cdd:TIGR01989 223 LPTGPIALLPLPDNNSTLVWSTSPEEALRLLSLPPEDFVDALNAAFDLGYSDHPYSYLLDYAMEKlNEDIGFRTE-GSKS 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  353 STGLPstfPWITGVQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIG 432
Cdd:TIGR01989 302 CFQVP---PRVIGVVDKSRAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIG 378

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 627808641  433 SSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALM 491
Cdd:TIGR01989 379 SISSLKPYERERYAKNVVLLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 39-496 1.49e-128

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 378.86  E-value: 1.49e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   39 DVVCIGGGPAGLSFASALKAHSatraLKVALIDAQDITTSRTgndgDAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQP 118
Cdd:TIGR01988   1 DIVIVGGGMVGLALALALARSG----LKVALIEATPLPAPAD----PGFDNRVSALSAASIRLLEKLGVWDKIEPARAQP 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  119 YHAMDVWDGVSGSKIHFDPRRYEAgSDYGVVAtmcENGNLTAALLQRLQALTTGDagagsvcdILDKTKVESIElgpqpe 198
Cdd:TIGR01988  73 IRDIHVSDGGSFGALRFDADEIGL-EALGYVV---ENRVLQQALWERLQELPNVT--------LLCPARVVELP------ 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  199 teetVDLSQWPIVMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaaDEVRTAFQRFLPTGP 278
Cdd:TIGR01988 135 ----RHSDHVELTLDDGQQLRARLLVGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHER----PHQGTAWERFTPTGP 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  279 IALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAFrlmpvdvnfmlspdmavtpseelRWREPATspsstglps 358
Cdd:TIGR01988 207 LALLPLPDNRSSLVWTLPPEEAERLLALSDEEFLAELQRAF-----------------------GSRLGAI--------- 254

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  359 tfpwitgVQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIGSSWCLD 438
Cdd:TIGR01988 255 -------TLVGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQ 327

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 627808641  439 GYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:TIGR01988 328 RYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
PRK07364 PRK07364
FAD-dependent hydroxylase;
25-498 3.08e-82

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 261.11  E-value: 3.08e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  25 SSAVSVTPGKPDI-YDVVCIGGGPAGLSFASALKAhsatRALKVALIDAQdiTTSRTGNDGDAYSnrcssLTPASSRFLR 103
Cdd:PRK07364   5 AATSPTLPSTRSLtYDVAIVGGGIVGLTLAAALKD----SGLRIALIEAQ--PAEAAAAKGQAYA-----LSLLSARIFE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 104 KIGAWDHInTGRVQPYHAMDVWDGVSGSKIHFDPRryEAGSDY-GVVAtmcENgnltAALLQRLQALTTGDAGAGSVCdi 182
Cdd:PRK07364  74 GIGVWEKI-LPQIGKFRQIRLSDADYPGVVKFQPT--DLGTEAlGYVG---EH----QVLLEALQEFLQSCPNITWLC-- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 183 ldKTKVESIELGpqpETEETVDLSQWPIvmtsQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEqtfa 262
Cdd:PRK07364 142 --PAEVVSVEYQ---QDAATVTLEIEGK----QQTLQSKLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHE---- 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 263 ADEVRTAFQRFLPTGPIALLPLPGNKASLVWsTSPQHAAK-LKQLPPNDFVAmvsaafrlmpvdvnfmlspdmavtpseE 341
Cdd:PRK07364 209 APHNDIAYERFWPSGPFAILPLPGNRCQIVW-TAPHAQAKaLLALPEAEFLA---------------------------E 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 342 LRWRepatspsstglpstfpwiTGVQEGSIAS------FPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAE 415
Cdd:PRK07364 261 LQQR------------------YGDQLGKLELlgdrflFPVQLMQSDRYVQHRLALVGDAAHCCHPVGGQGLNLGIRDAA 322

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 416 ALANQITYGMEHGMDIGSSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAA 495
Cdd:PRK07364 323 ALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLKRLALRLMT 402


                 ...
gi 627808641 496 GAK 498
Cdd:PRK07364 403 GLK 405
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
38-496 5.07e-75

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 241.40  E-value: 5.07e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALKAhsatRALKVALIDAQdiTTSRTGndGDAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQ 117
Cdd:PRK07608   6 FDVVVVGGGLVGASLALALAQ----SGLRVALLAPR--APPRPA--DDAWDSRVYAISPSSQAFLERLGVWQALDAARLA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWdGVSGSKIHFDPrrYEAGSDYgvVATMCENGNLTAALLQRLQ---ALTTGDAGagsvCDILDkTKVESIELG 194
Cdd:PRK07608  78 PVYDMRVF-GDAHARLHFSA--YQAGVPQ--LAWIVESSLIERALWAALRfqpNLTWFPAR----AQGLE-VDPDAATLT 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 195 pqpeteetvdlsqwpivmTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaaDEVRTAFQRF 273
Cdd:PRK07608 148 ------------------LADGQvLRADLVVGADGAHSWVRSQAGIKAERRPYRQTGVVANFKAER----PHRGTAYQWF 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 274 LPTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAA--FRLmpvdvnfmlspdmavtpsEELRWREPAtsp 351
Cdd:PRK07608 206 RDDGILALLPLPDGHVSMVWSARTAHADELLALSPEALAARVERAsgGRL------------------GRLECVTPA--- 264

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 352 sstglpstfpwitgvqegsiASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITyGMEHGMDI 431
Cdd:PRK07608 265 --------------------AGFPLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLA-GREPFRDL 323

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 627808641 432 GSSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:PRK07608 324 GDLRLLRRYERARREDILALQVATDGLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHALG 388
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 39-498 1.18e-71

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 233.12  E-value: 1.18e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  39 DVVCIGGGPAGLSFASALKahsaTRALKVALIDAQDITTSRtgndGDAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQP 118
Cdd:PRK08850   6 DVAIIGGGMVGLALAAALK----ESDLRIAVIEGQLPEEAL----NELPDVRVSALSRSSEHILRNLGAWQGIEARRAAP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 119 YHAMDVWDGVSGSKIHFDPRRYeAGSDYGVVAtmcENGNLTAALLQRLQALTTgdagagsvCDILDKTKVESIELGpqpE 198
Cdd:PRK08850  78 YIAMEVWEQDSFARIEFDAESM-AQPDLGHIV---ENRVIQLALLEQVQKQDN--------VTLLMPARCQSIAVG---E 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 199 TEETVDLsqwpivmtSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELeqtfAADEVRTAFQRFLPTG 277
Cdd:PRK08850 143 SEAWLTL--------DNGQaLTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVANVRT----VDPHNSVARQIFTPQG 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 278 PIALLPL-PGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAF--RLMPVDVnfmlspdmavtpseelrwrepatspsst 354
Cdd:PRK08850 211 PLAFLPMsEPNMSSIVWSTEPLRAEALLAMSDEQFNKALTAEFdnRLGLCEV---------------------------- 262

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 355 glpstfpwitgvqEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIGSS 434
Cdd:PRK08850 263 -------------VGERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEILALWQQGRDIGLK 329

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 627808641 435 WCLDGYnsERWAANNA--MLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAGAK 498
Cdd:PRK08850 330 RNLRGY--ERWRKAEAakMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRALGLK 393
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
38-496 7.15e-68

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 223.32  E-value: 7.15e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALKahSATRALKVALIDAqdITTSRTGNDGdaysnRCSSLTPASSRFLRKIGAWDHInTGRVQ 117
Cdd:PRK07333   2 CDVVIAGGGYVGLALAVALK--QAAPHLPVTVVDA--APAGAWSRDP-----RASAIAAAARRMLEALGVWDEI-APEAQ 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDgvsgSKIHfDPRR---------YEAGSDYgvvATMCENGNLTAALLQRLQALTTgdagagsvcDILDKTKV 188
Cdd:PRK07333  72 PITDMVITD----SRTS-DPVRpvfltfegeVEPGEPF---AHMVENRVLINALRKRAEALGI---------DLREATSV 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 189 ESIELGPQpetEETVDLSQWPIvmtsqgqLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaaDEVRT 268
Cdd:PRK07333 135 TDFETRDE---GVTVTLSDGSV-------LEARLLVAADGARSKLRELAGIKTVGWDYGQSGIVCTVEHER----PHGGR 200

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 269 AFQRFLPTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAF--RLmpvdvnfmlspdmavtpsEELRWre 346
Cdd:PRK07333 201 AEEHFLPAGPFAILPLKGNRSSLVWTERTADAERLVALDDLVFEAELEQRFghRL------------------GELKV-- 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 347 patspsstglpstfpwitgvqEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGME 426
Cdd:PRK07333 261 ---------------------LGKRRAFPLGLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEAAR 319

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 427 HGMDIGSSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:PRK07333 320 LGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVDRLPKLKSFFIRQAAG 389
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 39-496 4.53e-65

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 215.85  E-value: 4.53e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  39 DVVCIGGGPAGLSFASALKaHSAtraLKVALIDAQDITTSRTGNDGdAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQP 118
Cdd:PRK05714   4 DLLIVGAGMVGSALALALQ-GSG---LEVLLLDGGPLSVKPFDPQA-PFEPRVSALSAASQRILERLGAWDGIAARRASP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 119 YHAMDVWDGVSGSKIHFDPRRYEAgsdyGVVATMCENGNLTAALLQRLQALTTGdagagsvcdILDKTKVESIELGPQpe 198
Cdd:PRK05714  79 YSEMQVWDGSGTGQIHFSAASVHA----EVLGHIVENRVVQDALLERLHDSDIG---------LLANARLEQMRRSGD-- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 199 teetvdlsQWPIVMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTFAadevRTAFQRFLPTGP 278
Cdd:PRK05714 144 --------DWLLTLADGRQLRAPLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEPHR----ATAWQRFTDDGP 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 279 IALLPLPGNK----ASLVWSTSPQHAAKLKQLPPNDFVAMVSAAF--RLMPVdvnfmLSPDMAVTpseelrwrepatsps 352
Cdd:PRK05714 212 LAFLPLERDGdehwCSIVWSTTPEEAERLMALDDDAFCAALERAFegRLGEV-----LSADPRLC--------------- 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 353 stglpstfpwitgvqegsiasFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIG 432
Cdd:PRK05714 272 ---------------------VPLRQRHAKRYVEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLA 330

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 627808641 433 SSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:PRK05714 331 DVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLPLRWLRNTGLKLVDQMPEAKALFVRQALG 394
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 39-496 1.07e-64

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 214.10  E-value: 1.07e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   39 DVVCIGGGPAGLSFASALKAHSAtraLKVALIDAQDITTSRTGNDgdaysNRCSSLTPASSRFLRKIGAWDHINTgRVQP 118
Cdd:TIGR01984   1 DVIIVGGGLVGLSLALALSRLGK---IKIALIEANSPSAAQPGFD-----ARSLALSYGSKQILEKLGLWPKLAP-FATP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  119 YHAMDVWDgvsgsKIHFDPRRYEAgSDYGVVAT--MCENGNLTAALLQRLQALTtgdagagsVCDILDKTKVESIElgpq 196
Cdd:TIGR01984  72 ILDIHVSD-----QGHFGATHLRA-SEFGLPALgyVVELADLGQALLSRLALLT--------NIQLYCPARYKEII---- 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  197 PETEETVdlsqwpIVMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaaDEVRTAFQRFLPT 276
Cdd:TIGR01984 134 RNQDYVR------VTLDNGQQLRAKLLIAADGANSKVRELLSIPTEEHDYNQTALIANIRHEQ----PHQGCAFERFTPH 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  277 GPIALLPLPGNKA-SLVWSTSPQHAAKLKQLPPNDFVAMVSAAFRlmpvdvnfmlspdmavtpseelrWREPATSpsstg 355
Cdd:TIGR01984 204 GPLALLPLKDNYRsSLVWCLPSKQADTIANLPDAEFLAELQQAFG-----------------------WRLGKIT----- 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  356 lpstfpwitgvQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITygmEHGMDIGSSW 435
Cdd:TIGR01984 256 -----------QVGERKTYPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAEVLI---DARIDLGTYA 321

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 627808641  436 CLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:TIGR01984 322 LLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQAMG 382
PRK08013 PRK08013
oxidoreductase; Provisional
 38-496 1.32e-63

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 211.83  E-value: 1.32e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALKAhsatRALKVALIDAQDITTSRTGndgDAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQ 117
Cdd:PRK08013   4 VDVVIAGGGMVGLAVACGLQG----SGLRVAVLEQRVPEPLAAD---APPALRVSAINAASEKLLTRLGVWQDILARRAS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDGVSGSKIHFDprryeaGSDYGV--VATMCENGNLTAALLQRlqalttgdagAGSVCDI--LDKTKVESIEL 193
Cdd:PRK08013  77 CYHGMEVWDKDSFGRIAFD------DQSMGYshLGHIIENSVIHYALWQK----------AQQSSDItlLAPAELQQVAW 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 194 GpqpETEETVDLSqwpivmtSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTFAAdevrTAFQRF 273
Cdd:PRK08013 141 G---ENEAFLTLK-------DGSMLTARLVVGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDA----VARQVF 206

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 274 LPTGPIALLPLPG-NKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAFrlmpvdvnfmlspDMAVtpseelrwrepatsps 352
Cdd:PRK08013 207 HGDGILAFLPLSDpHLCSIVWSLSPEEAQRMQQAPEEEFNRALAIAF-------------DNRL---------------- 257

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 353 stGLPSTfpwitgvqEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIG 432
Cdd:PRK08013 258 --GLCEL--------ESERQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIG 327

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 627808641 433 SSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:PRK08013 328 QHLYLRRYERSRKHSAALMLAGMQGFRDLFAGNNPAKKLLRDIGLKLADTLPGVKPQLIRQAMG 391
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 38-482 1.09e-53

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 185.57  E-value: 1.09e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALkahsATRALKVALIDAQDITTSRTGNDGDAysnRCSSLTPASSRFLRKIGAWDHINTGRVQ 117
Cdd:PRK08020   6 TDIAIVGGGMVGAALALGL----AQHGFSVAVLEHAAPAPFDADSQPDV---RISAISAASVALLKGLGVWDAVQAMRSH 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDGvSGSKIHFDPR---RYEAGsdygvvaTMCENGNLTAALLQRLQAlttgdagagsvCDILdktkveSIELG 194
Cdd:PRK08020  79 PYRRLETWEW-ETAHVVFDAAelkLPELG-------YMVENRVLQLALWQALEA-----------HPNV------TLRCP 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 195 PQPETEETVDlSQWPIVMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaaDEVRTAFQRFL 274
Cdd:PRK08020 134 ASLQALQRDD-DGWELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVKCEN----PPGDSTWQQFT 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 275 PTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAF--RLMPVdvnfmlspdmavtpseelrwrepatSPS 352
Cdd:PRK08020 209 PSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHFpaRLGAV-------------------------TPV 263

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 353 STGlpstfpwitgvqegsiaSFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIG 432
Cdd:PRK08020 264 AAG-----------------AFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAWA 326

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|
gi 627808641 433 SSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVER 482
Cdd:PRK08020 327 SEAVLKRYQRRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQR 376
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 38-491 1.62e-53

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 183.22  E-value: 1.62e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALKAHSatraLKVALIDAQdittSRTGNDGdaysnRCSSLTPASSRFLRKIGAWDHInTGRVQ 117
Cdd:COG0654    4 TDVLIVGGGPAGLALALALARAG----IRVTVVERA----PPPRPDG-----RGIALSPRSLELLRRLGLWDRL-LARGA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDGVSGSKI-HFDPRryEAGSDYGVvatMCENGNLTAALLQRLQALTtgdagagsvCDILDKTKVESIElgpQ 196
Cdd:COG0654   70 PIRGIRVRDGSDGRVLaRFDAA--ETGLPAGL---VVPRADLERALLEAARALG---------VELRFGTEVTGLE---Q 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 197 PETEETVDLSqwpivmtSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELeqtfaadEVRTAFQRFLPt 276
Cdd:COG0654  133 DADGVTVTLA-------DGRTLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVRT-------ELRARLAAAGP- 197

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 277 gpiallplpgnkaslvwstspqhaaklkqlppnDFVAMVSAafrlmpvdvnfmlspdmavtpseelrwrepatspsstgl 356
Cdd:COG0654  198 ---------------------------------RLGELLEL--------------------------------------- 205

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 357 pstfpwitgvqeGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITygmEHGMDIGSSWC 436
Cdd:COG0654  206 ------------SPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAALAWKLA---AALRGRDDEAA 270

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 627808641 437 LDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALM 491
Cdd:COG0654  271 LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLKGGGL 325
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 38-496 6.75e-52

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 180.74  E-value: 6.75e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALkahsATRALKVALIDAQDITTSRTGNDGDAysnRCSSLTPASSRFLRKIGAWDHINTGRVQ 117
Cdd:PRK08849   4 YDIAVVGGGMVGAATALGF----AKQGRSVAVIEGGEPKAFEPSQPMDI---RVSAISQTSVDLLESLGAWSSIVAMRVC 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDgvsgskiHFDPR-RYEAGS-DYGVVATMCENGNLTAALLQRLQA---LTtgdagagsvcdILDKTKVESIE 192
Cdd:PRK08849  77 PYKRLETWE-------HPECRtRFHSDElNLDQLGYIVENRLIQLGLWQQFAQypnLT-----------LMCPEKLADLE 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 193 LGPQPETeetvdlsqwpIVMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTfaadEVRTAFQR 272
Cdd:PRK08849 139 FSAEGNR----------VTLESGAEIEAKWVIGADGANSQVRQLAGIGITAWDYRQHCMLINVETEQP----QQDITWQQ 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 273 FLPTGPIALLPLPGNKASLVWSTSPQhaaKLKQLppndfVAMVSAAFRlmpvdvnfmlspdmavtpSEELRWrepatsps 352
Cdd:PRK08849 205 FTPSGPRSFLPLCGNQGSLVWYDSPK---RIKQL-----SAMNPEQLR------------------SEILRH-------- 250

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 353 stgLPSTFPWITGVQEGSiasFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQItygmEHGMDIG 432
Cdd:PRK08849 251 ---FPAELGEIKVLQHGS---FPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKDVDVLLAET----EKQGVLN 320

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 627808641 433 SSwCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:PRK08849 321 DA-SFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKYALG 383
PRK09126 PRK09126
FAD-dependent hydroxylase;
38-498 1.07e-50

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 177.44  E-value: 1.07e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALKAHSatraLKVALIDAQdittSRTGNDGDAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQ 117
Cdd:PRK09126   4 SDIVVVGAGPAGLSFARSLAGSG----LKVTLIERQ----PLAALADPAFDGREIALTHASREILQRLGAWDRIPEDEIS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDGVSGSKIHFDPRryeaGSDYGVVATMCENGNLTAALLQrlQALTTGDAgagsvcDILDKTKVESIELGPQp 197
Cdd:PRK09126  76 PLRDAKVLNGRSPFALTFDAR----GRGADALGYLVPNHLIRRAAYE--AVSQQDGI------ELLTGTRVTAVRTDDD- 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 198 etEETVDLSqwpivmtSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfaaDEVRTAFQRFLPTG 277
Cdd:PRK09126 143 --GAQVTLA-------NGRRLTARLLVAADSRFSATRRQLGIGADMHDFGRTMLVCRMRHEL----PHHHTAWEWFGYGQ 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 278 PIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAF--RLmpvdvnfmlspdmavtpsEELRwrepatspsstg 355
Cdd:PRK09126 210 TLALLPLNGHLSSLVLTLPPDQIEALLALDPEAFAAEVTARFkgRL------------------GAMR------------ 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 356 lpstfpwitgvQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIGSSW 435
Cdd:PRK09126 260 -----------LVSSRHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAAS 328

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 436 CLDGYNSER-------WAANNAMLgvvdklqKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAGAK 498
Cdd:PRK09126 329 LLERYERKHrlatrplYHATNAIA-------ALYTDDRPPARLLRRAVLRAANRFPPLKQAIAKQLTGRK 391
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 38-496 2.17e-47

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 168.88  E-value: 2.17e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALkAHSATRALKVALIDAqditTSRTGNDGDAYSNRCSSLTPASSRFLRKIGAWDHInTGRVQ 117
Cdd:PRK05732   4 MDVIIVGGGMAGATLALAL-SRLSHGGLPVALIEA----FAPESDAHPGFDARAIALAAGTCQQLARLGVWQAL-ADCAT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWDgvsgsKIHFDPRRYEAgSDYGVVA--TMCENgnltAALLQRLQALTTGDAGAGSVCdildKTKVESIElgp 195
Cdd:PRK05732  78 PITHIHVSD-----RGHAGFVRLDA-EDYGVPAlgYVVEL----HDVGQRLFALLDKAPGVTLHC----PARVANVE--- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 196 qpETEETVDLSqwpivMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVA---TLELEQTfaadevrTAFQR 272
Cdd:PRK05732 141 --RTQGSVRVT-----LDDGETLTGRLLVAADGSHSALREALGIDWQQHPYEQVAVIAnvtTSEAHQG-------RAFER 206

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 273 FLPTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAFRlmpvdvnfmlspdmavtpseelrWREPAtsps 352
Cdd:PRK05732 207 FTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSWSDAQFLAELQQAFG-----------------------WRLGR---- 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 353 stglpstfpwITGVqeGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIG 432
Cdd:PRK05732 260 ----------ITHA--GKRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDIG 327

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 627808641 433 SSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:PRK05732 328 DYAVLQRYQQRRQQDREATIGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLPPARDWLARRTLG 391
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
39-496 6.23e-45

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 162.34  E-value: 6.23e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  39 DVVCIGGGPAGLSFASALkahsATRALKVALIDAQDITTSRtgndGDAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQP 118
Cdd:PRK08773   8 DAVIVGGGVVGAACALAL----ADAGLSVALVEGREPPRWQ----ADQPDLRVYAFAADNAALLDRLGVWPAVRAARAQP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 119 YHAMDVWDGVSGSKIHFDPRRYeaGSDYgvVATMCENGNLTAALLQRLQAlttgdAGAGSVCdildKTKVESIElgpqpE 198
Cdd:PRK08773  80 YRRMRVWDAGGGGELGFDADTL--GREQ--LGWIVENDLLVDRLWAALHA-----AGVQLHC----PARVVALE-----Q 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 199 TEETVDLSqwpivMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTFAAdevrTAFQRFLPTGP 278
Cdd:PRK08773 142 DADRVRLR-----LDDGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAFVDTEHPHQA----TAWQRFLPTGP 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 279 IALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAF--RLMPVDVnfmlspdmavtpseelrwrepaTSPSstgl 356
Cdd:PRK08773 213 LALLPFADGRSSIVWTLPDAEAERVLALDEAAFSRELTQAFaaRLGEVRV----------------------ASPR---- 266

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 357 pstfpwitgvqegsiASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYGMEHGMDIGSSWC 436
Cdd:PRK08773 267 ---------------TAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAAPHR 331

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 437 LDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAG 496
Cdd:PRK08773 332 LQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPLVDALWKRASG 391
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
34-491 2.47e-39

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 146.59  E-value: 2.47e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  34 KPDIYDVVCIGGGPAGLSFASALkahsATRALKVALIDAQdittsrtgndGDAYSNRCSSLTPASSRFLRKIGAWDHInT 113
Cdd:PRK07494   4 EKEHTDIAVIGGGPAGLAAAIAL----ARAGASVALVAPE----------PPYADLRTTALLGPSIRFLERLGLWARL-A 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 114 GRVQPYHAMDVWDGVS----GSKIHFDPRryEAGSD---YGVvatmcENGNLTAALLQRLQALTTgdagagsvcdiLDKT 186
Cdd:PRK07494  69 PHAAPLQSMRIVDATGrlirAPEVRFRAA--EIGEDafgYNI-----PNWLLNRALEARVAELPN-----------ITRF 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 187 KVESIELGPQpetEETVdlsqwpIVMTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVatLELEQTFAADE 265
Cdd:PRK07494 131 GDEAESVRPR---EDEV------TVTLADGTtLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALV--LNFTHSRPHQN 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 266 VRTAFQRflPTGPIALLPLPGNKASLVWSTSPQHAAKLKQLPPNDFVAMVSAAFRLM--PVDVnfmlspdmavtpseelr 343
Cdd:PRK07494 200 VSTEFHT--EGGPFTQVPLPGRRSSLVWVVRPAEAERLLALSDAALSAAIEERMQSMlgKLTL----------------- 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 344 wrepatspsstglpstfpwitgvqEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITy 423
Cdd:PRK07494 261 ------------------------EPGRQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLVEIVE- 315

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 627808641 424 gmEHGMDIGSSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALM 491
Cdd:PRK07494 316 --DRPEDPGSAAVLAAYDRARRPDILSRTASVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFM 381
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
31-490 3.96e-38

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 143.67  E-value: 3.96e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  31 TPGKPDiYDVVCIGGGPAGLSFASALKAHSATRALKVALIDAQDitTSRTGNDgdaysNRCSSLTPASSRFLRKIGAWdh 110
Cdd:PRK06996   6 SMAAPD-FDIAIVGAGPVGLALAGWLARRSATRALSIALIDARE--PAASAND-----PRAIALSHGSRVLLETLGAW-- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 111 intgrvqPYHAMDVwdgvsgSKIHFDPRRYEA-----GSDYGVVA--TMCENGNLTAALLQRLQAltTGDAGAGSVCDIL 183
Cdd:PRK06996  76 -------PADATPI------EHIHVSQRGHFGrtlidRDDHDVPAlgYVVRYGSLVAALARAVRG--TPVRWLTSTTAHA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 184 DKTKVESIELgpqpeTEETVDLsqwpivmtsQGQLAARLLVGADGA--NSPVRQFVDIPSHGwDYGQHGVVATLeleqTF 261
Cdd:PRK06996 141 PAQDADGVTL-----ALGTPQG---------ARTLRARIAVQAEGGlfHDQKADAGDSARRR-DYGQTAIVGTV----TV 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 262 AADEVRTAFQRFLPTGPIALLPLPGNKA---SLVWSTSPQHAAKLKQLPPNDFVAMVSAAF--RLmpvdvnfmlspdmav 336
Cdd:PRK06996 202 SAPRPGWAWERFTHEGPLALLPLGGPRQadyALVWCCAPDEAARRAALPDDAFLAELGAAFgtRM--------------- 266

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 337 tpseelrwrepatspsstglpSTFpwitgVQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEA 416
Cdd:PRK06996 267 ---------------------GRF-----TRIAGRHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGLRDAHT 320

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 627808641 417 LANQITygmEHGMdigSSWCLDGYNSERwAANNAM-LGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGAL 490
Cdd:PRK06996 321 LADALS---DHGA---TPLALATFAARR-ALDRRVtIGATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHAL 388
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 39-498 7.28e-29

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 117.33  E-value: 7.28e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  39 DVVCIGGGPAGLSFASALkahsATRALKVALIDAQDITTSRTGNDgdaysNRCSSLTPASSRFLRKIGAWDHIN--TGRV 116
Cdd:PRK06617   3 NTVILGCGLSGMLTALSF----AQKGIKTTIFESKSVKSPEFFKD-----IRTTALTPHSKNFLFSIDIWEELEkfVAEM 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 117 QPYHAMDVwdgvSGSKIhFDPRRyeagSDYGVVATMCENGNLTAALLQRLqalttgdagagsvcdildkTKVESIELGPQ 196
Cdd:PRK06617  74 QDIYVVDN----KASEI-LDLRN----DADAVLGYVVKNSDFKKILLSKI-------------------TNNPLITLIDN 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 197 PETEETVDLSQWPIVMTSQGQLAARLLVGADGANSPVRqfvdipSHgwdYGQHGVVATLELEQTFAADEVR----TAFQR 272
Cdd:PRK06617 126 NQYQEVISHNDYSIIKFDDKQIKCNLLIICDGANSKVR------SH---YFANEIEKPYQTALTFNIKHEKphenCAMEH 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 273 FLPTGPIALLPLPGNKAS-LVWSTSPQHAAKLKQLPpndfvamvsaafrlmpvdvnfmlspdmavtpSEELRWREPATSP 351
Cdd:PRK06617 197 FLPLGPFALLPLKDQYASsVIWSTSSDQAALIVNLP-------------------------------VEEVRFLTQRNAG 245

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 352 SSTGLpstfpwITGVQEgsIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALAnqitygmehgMDI 431
Cdd:PRK06617 246 NSLGK------ITIDSE--ISSFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILS----------MIV 307

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 627808641 432 GSSWCLDGYNSERWAANNAMLGVVDKLQKLYSASAGPVVWSRSLGLEAVERMSWVKGALMGVAAGAK 498
Cdd:PRK06617 308 SNNGTLQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYAMGKR 374
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 38-444 2.20e-19

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 89.31  E-value: 2.20e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   38 YDVVCIGGGPAGLSFASALkahsATRALKVALIDAQDiTTSRTGndgdaysnRCSSLTPASSRFLRKIGAWDHI-NTGRV 116
Cdd:pfam01494   2 TDVLIVGGGPAGLMLALLL----ARAGVRVVLVERHA-TTSVLP--------RAHGLNQRTMELLRQAGLEDRIlAEGVP 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  117 QPYHAMDVWDGVSGSKIHFDpRRYEAGSDYGVVatmcengNLTAALLQRLQALTtgdagagsvCDILDKTKVESIElgpQ 196
Cdd:pfam01494  69 HEGMGLAFYNTRRRADLDFL-TSPPRVTVYPQT-------ELEPILVEHAEARG---------AQVRFGTEVLSLE---Q 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  197 PETEETVDLSQwpiVMTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTFAADEVRTAFqrflp 275
Cdd:pfam01494 129 DGDGVTAVVRD---RRDGEEYtVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDLSDPVERAFV----- 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  276 tgpIALLPLPGNKASLVwstspqhaaklkqlppndfVAMVSAAFRLMPVDVNFMLSPDmavTPSEELRWREPATS-PSST 354
Cdd:pfam01494 201 ---HYLIYAPHSRGFMV-------------------GPWRSAGRERYYVQVPWDEEVE---ERPEEFTDEELKQRlRSIV 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  355 GLPSTFPWITGVQegsiaSFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQIT--YGMEhgmdiG 432
Cdd:pfam01494 256 GIDLALVEILWKS-----IWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLAavLRGQ-----A 325

                         410
                  ....*....|..
gi 627808641  433 SSWCLDGYNSER 444
Cdd:pfam01494 326 GESLLDTYSAER 337
PRK07045 PRK07045
putative monooxygenase; Reviewed
 39-452 4.34e-13

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 70.71  E-value: 4.34e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  39 DVVCIGGGPAGLSFASALkahsATRALKVALIDAQDITTSRTGNDgdaysnrcsSLTPASSRFLRKIGAWDHINT--GRV 116
Cdd:PRK07045   7 DVLINGSGIAGVALAHLL----GARGHSVTVVERAARNRAQNGAD---------LLKPSGIGVVRAMGLLDDVFAagGLR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 117 QpyHAMDVWDgvSGSKI-HFDprrYEAGSDYGVVATM-CENgnLTAALLQRLQALTTgdagagsvCDILDKTKVESIElg 194
Cdd:PRK07045  74 R--DAMRLYH--DKELIaSLD---YRSASALGYFILIpCEQ--LRRLLLAKLDGLPN--------VRLRFETSIERIE-- 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 195 pqPETEETVDlsqwPIVMTSQGQLAARLLVGADGANSPVRQFV-DIPSHGWDYGQHGVVATLELeqtfaADEVRTAFQRF 273
Cdd:PRK07045 135 --RDADGTVT----SVTLSDGERVAPTVLVGADGARSMIRDDVlRMPAERVPYATPMAFGTIAL-----TDSVRECNRLY 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 274 LPT--GPIALLPLPGNKASLVWStspqhaaklkqLPPNDFVAMvsaafrlmpvdvnfmlspdMAVTPSEELRWR------ 345
Cdd:PRK07045 204 VDSnqGLAYFYPIGDQATRLVVS-----------FPADEMQGY-------------------LADTTRTKLLARlnefvg 253

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 346 -EPATSPSSTGLPSTFPWItgvqegsiasfPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQITYG 424
Cdd:PRK07045 254 dESADAMAAIGAGTAFPLI-----------PLGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLH 322

                        410       420
                 ....*....|....*....|....*...
gi 627808641 425 MEHGMDIGSSwcLDGYNSERWAANNAML 452
Cdd:PRK07045 323 LSGQIALADA--LERFERIRRPVNEAVI 348
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
45-421 5.92e-10

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 59.98  E-value: 5.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  45 GGPAGLSFASALKAHSatraLKVALIDAQdiTTSRTGNDGDAysnrcssLTPASSRFLRKIGAWDHIntgrVQPYHAMDV 124
Cdd:COG0644    1 AGPAGSAAARRLARAG----LSVLLLEKG--SFPGDKICGGG-------LLPRALEELEPLGLDEPL----ERPVRGARF 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 125 WdGVSGSKIHFDPRRYeagsdygvVATMCENGNLTAALLQRLQAlttgdAGAgsvcDILDKTKVESIElgpqpeteetVD 204
Cdd:COG0644   64 Y-SPGGKSVELPPGRG--------GGYVVDRARFDRWLAEQAEE-----AGA----EVRTGTRVTDVL----------RD 115

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 205 LSQWPIVMTSQGQLAARLLVGADGANSPVRQFVDIPShgwdygqhgvvatleleqtfaadevrtafqrflptgpiallpl 284
Cdd:COG0644  116 DGRVVVRTGDGEEIRADYVVDADGARSLLARKLGLKR------------------------------------------- 152

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 285 pgnkaslvWSTSPQHaaklkqlppndfvaMVSAAFRLMPVDVNFMLSPDMAvtpseELRWREpatspsstGLPSTFPWIT 364
Cdd:COG0644  153 --------RSDEPQD--------------YALAIKEHWELPPLEGVDPGAV-----EFFFGE--------GAPGGYGWVF 197

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 627808641 365 GVQEGSIA-SFPLRmRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQI 421
Cdd:COG0644  198 PLGDGRVSvGIPLG-GPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAI 254
PRK08244 PRK08244
monooxygenase;
280-452 1.33e-09

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 60.14  E-value: 1.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 280 ALLPLPGNKASLvwsTSPQHAAKLKQLPPNDFVAMVSAAFRLMPVDVN------FMLSPDMAVTPS------EELRWREP 347
Cdd:PRK08244 165 AGIAFPGTDATF---TAMLGDVVLKDPPPSSVLSLCTREGGVMIVPLSggiyrvLIIDPERPQVPKdepvtlEELKTSLI 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 348 ATSPSSTGLPSTFpWITgvqegsiaSFPLRMRHADTYTGHRVALIGDAAHtIH-PLAGQGLNLGLADAEALANQITYGME 426
Cdd:PRK08244 242 RICGTDFGLNDPV-WMS--------RFGNATRQAERYRSGRIFLAGDAAH-IHfPAGGQGLNVGLQDAMNLGWKLAAAIK 311

                        170       180
                 ....*....|....*....|....*...
gi 627808641 427 hgmdiGS--SWCLDGYNSERWAANNAML 452
Cdd:PRK08244 312 -----GWapDWLLDSYHAERHPVGTALL 334
PRK06184 PRK06184
hypothetical protein; Provisional
 192-414 1.13e-08

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 57.30  E-value: 1.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 192 ELGPQPE-TEETVDLSQWP------IVMTSQGQ-LAARLLVGADGANSPVRQFVDIPSHGwdygqhgvvATLELEQTFAA 263
Cdd:PRK06184 121 ELGHRVEfGCELVGFEQDAdgvtarVAGPAGEEtVRARYLVGADGGRSFVRKALGIGFPG---------ETLGIDRMLVA 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 264 DE-----VRTAFQRFLP--TGPIALLPLPGnkaslvwstspqhaaklkqlppndfvamvSAAFRLMPVdvnfmLSPDMAV 336
Cdd:PRK06184 192 DVsltglDRDAWHQWPDgdMGMIALCPLPG-----------------------------TDLFQIQAP-----LPPGGEP 237

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 337 TPSEE-LRwrepATSPSSTGLPstfpWITgVQEGSIAS-FPLRMRHADTYTGHRVALIGDAAHtIHPLAG-QGLNLGLAD 413
Cdd:PRK06184 238 DLSADgLT----ALLAERTGRT----DIR-LHSVTWASaFRMNARLADRYRVGRVFLAGDAAH-VHPPAGgQGLNTSVQD 307


                 .
gi 627808641 414 A 414
Cdd:PRK06184 308 A 308
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 33-447 1.46e-07

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 53.72  E-value: 1.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  33 GKPDIYDVVCIGGGPAGLSFASALkahsATRALKVALIDAQDitTSRTGNDGDAYSNRcsSLT-----PASSRFLRKIGA 107
Cdd:PRK08132  19 DDPARHPVVVVGAGPVGLALAIDL----AQQGVPVVLLDDDD--TLSTGSRAICFAKR--SLEifdrlGCGERMVDKGVS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 108 WdhiNTGRVqpYHAMD-VWdgvsgskiHFD--PrryEAGSDYgvvATMCengNLT-----AALLQRLQALttgdagagSV 179
Cdd:PRK08132  91 W---NVGKV--FLRDEeVY--------RFDllP---EPGHRR---PAFI---NLQqyyveGYLVERAQAL--------PN 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 180 CDILDKTKVESIElgpqpETEETVDLSqwpiVMTSQG--QLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLEL 257
Cdd:PRK08132 141 IDLRWKNKVTGLE-----QHDDGVTLT----VETPDGpyTLEADWVIACDGARSPLREMLGLEFEGRTFEDRFLIADVKM 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 258 EQTFAADevRTAFqrFLPT---GPIALL-PLPGNkaslVWSTSpqhaaklKQLPPN-DFVAMVSAAfRLMPvDVNFMLSP 332
Cdd:PRK08132 212 KADFPTE--RWFW--FDPPfhpGQSVLLhRQPDN----VWRID-------FQLGWDaDPEAEKKPE-NVIP-RVRALLGE 274

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 333 DMAVTPSeelrwrepatspsstglpstfpWItgvqegSIASFP-LRMrhaDTYTGHRVALIGDAAHTIHPLAGQGLNLGL 411
Cdd:PRK08132 275 DVPFELE----------------------WV------SVYTFQcRRM---DRFRHGRVLFAGDAAHQVSPFGARGANSGI 323

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 627808641 412 ADAEALANQITYGMEhgmDIGSSWCLDGYNSERWAA 447
Cdd:PRK08132 324 QDADNLAWKLALVLR---GRAPDSLLDSYASEREFA 356
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 38-422 1.52e-07

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 53.70  E-value: 1.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  38 YDVVCIGGGPAGLSFASALkahsaTRALKVALIDAQDITTSRTGNDGDAysnrcssLTPASSRFLRKIGAwDHINTGRVQ 117
Cdd:PTZ00367  34 YDVIIVGGSIAGPVLAKAL-----SKQGRKVLMLERDLFSKPDRIVGEL-------LQPGGVNALKELGM-EECAEGIGM 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 118 PYHAMDVWD------------GVSGSKIHF-----DPRRYeagsdygVVATMCENgnltAALLQR-LQALTTGDAGAGSV 179
Cdd:PTZ00367 101 PCFGYVVFDhkgkqvklpygaGASGVSFHFgdfvqNLRSH-------VFHNCQDN----VTMLEGtVNSLLEEGPGFSER 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 180 CDILDKTKVESIELGPQPETEEtvDLSQWPIVMTSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVvaTLELEQ 259
Cdd:PTZ00367 170 AYGVEYTEAEKYDVPENPFRED--PPSANPSATTVRKVATAPLVVMCDGGMSKFKSRYQHYTPASENHSHFV--GLVLKN 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 260 TFAADEVR-TAFqrFLPTGPIALLPLPGNKASLVwstspqhaaklkqlppndfvamvsaafrlmpVDVNFMLSPDMavtp 338
Cdd:PTZ00367 246 VRLPKEQHgTVF--LGKTGPILSYRLDDNELRVL-------------------------------VDYNKPTLPSL---- 288

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 339 SEELRWREPATSPSstgLPS----TFPWITgVQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADA 414
Cdd:PTZ00367 289 EEQSEWLIEDVAPH---LPEnmreSFIRAS-KDTKRIRSMPNARYPPAFPSIKGYVGIGDHANQRHPLTGGGMTCCFSDC 364


                 ....*...
gi 627808641 415 EALANQIT 422
Cdd:PTZ00367 365 IRLAKSLT 372
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 38-240 2.60e-07

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 52.32  E-value: 2.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641   38 YDVVCIGGGPAGLSFAsalkAHSATRALKVALIDAQDITTSRTGndGDAYSNRCSSLT--PASSRFLRKIGAWDHINTGR 115
Cdd:TIGR02032   1 YDVVVVGAGPAGASAA----YRLADKGLRVLLLEKKSFPRYKPC--GGALSPRALEELdlPGELIVNLVRGARFFSPNGD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  116 -VQPYhamdvWDGVSGSKI---HFDPrryeagsdygvvatmcengnltaaLLQRlQALTTGdagagsvCDILDKTKVESI 191
Cdd:TIGR02032  75 sVEIP-----IETELAYVIdrdAFDE------------------------QLAE-RAQEAG-------AELRLGTRVLDV 117

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 627808641  192 elgPQPETEETVdlsqwpIVMTSQGQLAARLLVGADGANSPVRQFVDIP 240
Cdd:TIGR02032 118 ---EIHDDRVVV------IVRGSEGTVTAKIVIGADGSRSIVAKKLGLK 157
PRK06834 PRK06834
hypothetical protein; Provisional
 196-414 3.53e-07

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 52.71  E-value: 3.53e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 196 QPETEETVDLSqwpivmtSQGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTFAADEVRT-----AF 270
Cdd:PRK06834 128 QDDTGVDVELS-------DGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWGVHRDalgihAF 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 271 QRFLPTGPIALLplpgnkaslvwsTSPQHAAKLKQLPPNDFVAMVSAAFRlmpvdvnfmlsPDMAVtpsEELRWrepats 350
Cdd:PRK06834 201 GRLEDEGPVRVM------------VTEKQVGATGEPTLDDLREALIAVYG-----------TDYGI---HSPTW------ 248

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 627808641 351 psstglpstfpwitgvqegsIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADA 414
Cdd:PRK06834 249 --------------------ISRFTDMARQAASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQDA 292
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
215-418 1.08e-06

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 51.06  E-value: 1.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 215 QGQLAARLLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQtfAADEVRTAFQRFLPTGPIALLPLPGNKasLVWS 294
Cdd:PRK06183 158 RETVRARYVVGCDGANSFVRRTLGVPFEDLTFPERWLVVDVLIAN--DPLGGPHTYQYCDPARPYTSVRLPHGR--RRWE 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 295 tspqhaaklkqlppndfvamvsaaFRLMPVDvnfmlSPDMAVTPSEELRWREPatspsstglpstfpWITGVQEGSIasf 374
Cdd:PRK06183 234 ------------------------FMLLPGE-----TEEQLASPENVWRLLAP--------------WGPTPDDAEL--- 267

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 627808641 375 plrMRHAdTYTGH----------RVALIGDAAHTIHPLAGQGLNLGLADAEALA 418
Cdd:PRK06183 268 ---IRHA-VYTFHarvadrwrsgRVLLAGDAAHLMPPFAGQGMNSGIRDAANLA 317
PRK06185 PRK06185
FAD-dependent oxidoreductase;
391-419 8.71e-06

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 47.93  E-value: 8.71e-06
                         10        20
                 ....*....|....*....|....*....
gi 627808641 391 LIGDAAHTIHPLAGQGLNLGLADAEALAN 419
Cdd:PRK06185 288 CIGDAAHAMSPVGGVGINLAIQDAVAAAN 316
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 368-444 5.06e-05

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 45.56  E-value: 5.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 368 EGSIAsfPLR------MRHAdtytghRVALIGDAAHTIHPLAGQGLNLGLADAEALANqityGMEHGMDIGSSWCLDGYn 441
Cdd:PRK08243 262 EKSIA--PLRsfvaepMQYG------RLFLAGDAAHIVPPTGAKGLNLAASDVRYLAR----ALVEFYREGDTALLDAY- 328


                 ...
gi 627808641 442 SER 444
Cdd:PRK08243 329 SAT 331
PRK06126 PRK06126
hypothetical protein; Provisional
 39-418 9.99e-05

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 44.98  E-value: 9.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641  39 DVVCIGGGPAGLSFASALkahsATRALKVALIDAQDittsrtgndGDAYSNRCSSLTPASSRFLRKIGAWDHINTGRVQP 118
Cdd:PRK06126   9 PVLIVGGGPVGLALALDL----GRRGVDSILVERKD---------GTAFNPKANTTSARSMEHFRRLGIADEVRSAGLPV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 119 YHAMDV--WDGVSGSKIH-FD-PRRYEAGSDYGVVATmcenGNLTAALLQR-----LQALTTGDAGAGSVCDILDKTKVE 189
Cdd:PRK06126  76 DYPTDIayFTRLTGYELArFRlPSAREAITPVGGPDG----SWPSPELPHRipqkyLEPILLEHAAAQPGVTLRYGHRLT 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 190 SIElgpqpETEETVDLSQWPIVMTSQGQLAARLLVGADGANSPVRQFVDIPSHGwDYGQHGVVATLeleqtFAADEVRTA 269
Cdd:PRK06126 152 DFE-----QDADGVTATVEDLDGGESLTIRADYLVGCDGARSAVRRSLGISYEG-TSGLQRDLSIY-----IRAPGLAAL 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 270 FqrflptgpiallplPGNKASLVWSTSPQHAAKLKQLPPNDfvamVSAAFRLMPVDVNFmlspdmavtPSEELRWREPAT 349
Cdd:PRK06126 221 V--------------GHDPAWMYWLFNPDRRGVLVAIDGRD----EWLFHQLRGGEDEF---------TIDDVDARAFVR 273

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 627808641 350 ----SPSSTGLPSTFPWITgvqegsiasfplRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALA 418
Cdd:PRK06126 274 rgvgEDIDYEVLSVVPWTG------------RRLVADSYRRGRVFLAGDAAHLFTPTGGYGMNTGIGDAVNLA 334
PRK08255 PRK08255
bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;
389-451 1.13e-04

bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;


Pssm-ID: 236203 [Multi-domain]  Cd Length: 765  Bit Score: 44.93  E-value: 1.13e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 627808641 389 VALIGDAAHTIHPLAGQGLNLGLADAEALANQITygmEHGMDIGSSwcLDGYNSERW--------AANNAM 451
Cdd:PRK08255 271 VVLMGDAAHTAHFSIGSGTKLALEDAIELARCLH---EHPGDLPAA--LAAYEEERRvevlriqnAARNST 336
PRK07190 PRK07190
FAD-binding protein;
388-444 4.75e-04

FAD-binding protein;


Pssm-ID: 235955 [Multi-domain]  Cd Length: 487  Bit Score: 42.49  E-value: 4.75e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 627808641 388 RVALIGDAAHtIHPL-AGQGLNLGLADAEALANQITYGMEHgmdiGSSW-CLDGYNSER 444
Cdd:PRK07190 276 RIFLAGDACH-IHSVnGGQGLNTGLADAFNLIWKLNMVIHH----GASPeLLQSYEAER 329
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 38-71 7.35e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 42.09  E-value: 7.35e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 627808641  38 YDVVCIGGGPAGLSFASALKAHSatraLKVALID 71
Cdd:PRK06292   4 YDVIVIGAGPAGYVAARRAAKLG----KKVALIE 33
SE pfam08491
Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which ...
 361-422 1.44e-03

Squalene epoxidase; This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.


Pssm-ID: 400679  Cd Length: 276  Bit Score: 40.39  E-value: 1.44e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 627808641  361 PWITGVQEGSIASFPLRMRHADTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQIT 422
Cdd:pfam08491 104 SFLAALEEGKIRSMPNSFLPASKNRKKGLILLGDALNMRHPLTGGGMTVGLNDIVLLRKLLG 165
PRK06753 PRK06753
hypothetical protein; Provisional
 210-421 1.87e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 40.44  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 210 IVMTSQGQLAARLLVGADGANSPVRQFVDiPSHGWDYGQH----GVVATLELEQTfaadevRTAFQRFLPTGPIALLPLP 285
Cdd:PRK06753 131 IHFADGESEAFDLCIGADGIHSKVRQSVN-ADSKVRYQGYtcfrGLIDDIDLKLP------DCAKEYWGTKGRFGIVPLL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 286 GNKAslVWSTSPqhAAKLKQLPPNDFV-AMVSAAFRLMPVDVNFMLSpdmavTPSEelrwrepatspsstglpstfpwiT 364
Cdd:PRK06753 204 NNQA--YWFITI--NAKERDPKYSSFGkPHLQAYFNHYPNEVREILD-----KQSE-----------------------T 251

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 627808641 365 GVQEGSIASF-PLrmrhaDTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQI 421
Cdd:PRK06753 252 GILHHDIYDLkPL-----KSFVYGRIVLLGDAAHATTPNMGQGAGQAMEDAIVLANCL 304
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
38-72 1.88e-03

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 40.49  E-value: 1.88e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 627808641  38 YDVVCIGGGPAGLSFASAlkahsATRA-LKVALIDA 72
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIY-----AARAgLKTLVIEG 31
PRK07588 PRK07588
FAD-binding domain;
222-418 2.57e-03

FAD-binding domain;


Pssm-ID: 169028 [Multi-domain]  Cd Length: 391  Bit Score: 40.10  E-value: 2.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 222 LLVGADGANSPVRQFVDIPSHGWDYGQHGVVATLELEQTFAADEvRTAFQRFLPTGPIALLPLPGNKASLVWSTSPQHAA 301
Cdd:PRK07588 149 LVIGADGLHSHVRRLVFGPERDFEHYLGCKVAACVVDGYRPRDE-RTYVLYNEVGRQVARVALRGDRTLFLFIFRAEHDN 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 627808641 302 KlkQLPPNDFVAMVSAAFRlmpvDVNFMlSPDM--AVTPSEELrwrepatspsstglpstfpWITGVQEgsiasfpLRMr 379
Cdd:PRK07588 228 P--PLTPAEEKQLLRDQFG----DVGWE-TPDIlaALDDVEDL-------------------YFDVVSQ-------IRM- 273

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 627808641 380 haDTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALA 418
Cdd:PRK07588 274 --DRWSRGRVALVGDAAACPSLLGGEGSGLAITEAYVLA 310
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 38-72 3.91e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.22  E-value: 3.91e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 627808641   38 YDVVCIGGGPAGLSFASALKAHSAtralKVALIDA 72
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGG----KVTLIED 31
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 38-75 4.21e-03

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 39.74  E-value: 4.21e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 627808641  38 YDVVCIGGGPAGlsFASALkaHSATRALKVALIDAQDI 75
Cdd:PRK06416   5 YDVIVIGAGPGG--YVAAI--RAAQLGLKVAIVEKEKL 38
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 38-72 5.05e-03

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 39.30  E-value: 5.05e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 627808641  38 YDVVCIGGGPAGLsfASALKAhsATRALKVALIDA 72
Cdd:COG1249    4 YDLVVIGAGPGGY--VAAIRA--AQLGLKVALVEK 34
HI0933_like pfam03486
HI0933-like protein;
38-72 5.69e-03

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 39.10  E-value: 5.69e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 627808641   38 YDVVCIGGGPAGLsFASalkAHSATRALKVALIDA 72
Cdd:pfam03486   1 FDVIVIGGGAAGL-MAA---ISAAKRGRRVLLIEK 31
PRK05868 PRK05868
FAD-binding protein;
382-421 6.27e-03

FAD-binding protein;


Pssm-ID: 180297 [Multi-domain]  Cd Length: 372  Bit Score: 38.81  E-value: 6.27e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 627808641 382 DTYTGHRVALIGDAAHTIHPLAGQGLNLGLADAEALANQI 421
Cdd:PRK05868 277 DRWSRGRVALVGDAGYCCSPLSGQGTSVALLGAYILAGEL 316
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
43-90 6.87e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 35.20  E-value: 6.87e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 627808641   43 IGGGPAGLSFASALKAHSatraLKVALIDAQDittsRTGndGDAYSNR 90
Cdd:pfam13450   2 VGAGLAGLVAAALLAKRG----FRVLVLEKRD----RLG--GNAYSYR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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