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Conserved domains on  [gi|597938946|ref|XP_007323817|]
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hypothetical protein SERLADRAFT_479380 [Serpula lacrymans var. lacrymans S7.9]

Protein Classification

4-hydroxybenzoate octaprenyltransferase( domain architecture ID 10195474)

4-hydroxybenzoate octaprenyltransferase catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate in a Mg2+-sensitive manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 1-256 1.36e-89

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


:

Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 266.25  E-value: 1.36e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   1 MAAYSVDLPlksIMTQLSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLL 80
Cdd:cd13959   22 LAAGGLPLP---LLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVKEALLFLAVQLLLGLALLL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  81 LTSPTAGLVGLLGIFpLHALYPLMKRWTWWPQAWLGLAMNWGYPVAWLSITTLNLPVVATFFCGTICWSIFYDTIYACQD 160
Cdd:cd13959   99 QLNPLTILLSPIALL-LVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYLAVIFWTAGYDTIYAHQD 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 161 REDDVKAGVGSTAVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYVVScgGGAIHMCWQLLSWDMKLP-SSCLAKF 239
Cdd:cd13959  178 REDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGL--GAAAHLLWQEHRLDLPDPlRSCLAFF 255

                        250
                 ....*....|....*..
gi 597938946 240 RSNGDLGYILLAGMLLD 256
Cdd:cd13959  256 LSNGWVGLLLFAGLLLD 272
 
Name Accession Description Interval E-value
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 1-256 1.36e-89

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 266.25  E-value: 1.36e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   1 MAAYSVDLPlksIMTQLSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLL 80
Cdd:cd13959   22 LAAGGLPLP---LLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVKEALLFLAVQLLLGLALLL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  81 LTSPTAGLVGLLGIFpLHALYPLMKRWTWWPQAWLGLAMNWGYPVAWLSITTLNLPVVATFFCGTICWSIFYDTIYACQD 160
Cdd:cd13959   99 QLNPLTILLSPIALL-LVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYLAVIFWTAGYDTIYAHQD 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 161 REDDVKAGVGSTAVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYVVScgGGAIHMCWQLLSWDMKLP-SSCLAKF 239
Cdd:cd13959  178 REDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGL--GAAAHLLWQEHRLDLPDPlRSCLAFF 255

                        250
                 ....*....|....*..
gi 597938946 240 RSNGDLGYILLAGMLLD 256
Cdd:cd13959  256 LSNGWVGLLLFAGLLLD 272
ubiA_proteo TIGR01474
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ...
 1-256 6.46e-70

4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 130539  Cd Length: 281  Bit Score: 216.42  E-value: 6.46e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946    1 MAAYSVDLPLKSImtqLSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLL 80
Cdd:TIGR01474  29 LAAQAGGIPPLYL---LGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLASGAVSVRQAILFLLVQLLVALGVLL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   81 LTSPTAGLVGLLGIFPLhALYPLMKRWTWWPQAWLGLAMNWGYPVAWLSITTlNLPVVA-TFFCGTICWSIFYDTIYACQ 159
Cdd:TIGR01474 106 QLNPLTILLGVASLALV-ATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTG-DLSTAAwVLYLANILWTLGYDTIYAMQ 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  160 DREDDVKAGVGSTAVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYvVSCGGGAIHMCWQLLSWDMKLPSSCLAKF 239
Cdd:TIGR01474 184 DKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYY-LGLAAAALLLIRQIATLDIRDPENCLKLF 262

                         250
                  ....*....|....*..
gi 597938946  240 RSNGDLGYILLAGMLLD 256
Cdd:TIGR01474 263 KANNYVGLLLFAGIALG 279
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
 14-255 3.21e-61

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 194.52  E-value: 3.21e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  14 MTQLSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLG 93
Cdd:PLN02809  44 LKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASS 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  94 IFpLHALYPLMKRWTWWPQAWLGLAMNWGYPVAWLSIT-TLNLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGST 172
Cdd:PLN02809 124 LL-LVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKgSLDPAVVLPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKST 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 173 AVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYvVSCGGGAIHMCWQLLSWDMKLPSSCLAKFRSNGDLGYILLAG 252
Cdd:PLN02809 203 ALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYY-AGLAAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAG 281


                 ...
gi 597938946 253 MLL 255
Cdd:PLN02809 282 IVL 284
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 21-255 2.28e-53

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 174.26  E-value: 2.28e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  21 AIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFpLHAL 100
Cdd:COG0382   43 VLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGRISLREALLLAIVLLLLALALALLLNPLTFLLALAALA-LAWA 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 101 YPL-MKRWTWWPQAWLGLAMNWGYPVAWLSITTLNLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFGSW 179
Cdd:COG0382  122 YSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPLSAWLLALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVR 201

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 597938946 180 IRPILTG-FATTFIACVVYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSWD--MKLPSSCLAKFRSNGDLGYILLAGMLL 255
Cdd:COG0382  202 DALIIAGvLYALAVLLLLLLGLLAGLGLLYLLGLLAALLLLYLSQLWLLRprKKDPARALKLFKLNMLLGLLLFLGIAL 280
UbiA pfam01040
UbiA prenyltransferase family;
21-239 4.08e-40

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 138.90  E-value: 4.08e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   21 AIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFpLHAL 100
Cdd:pfam01040  26 LLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALGLLLLLLLNPLTALLGLAALL-LYVL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  101 YPL-MKRWTWWPQAWLGLAMNWGYPVAWLSITTLNLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFGSW 179
Cdd:pfam01040 105 YTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIALANDLRDREDDRKAGIKTLPVVLGRK 184

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  180 IRPILTGFATTFIACVVYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSWDMKLPSSCLAKF 239
Cdd:pfam01040 185 AARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPKKDAKAF 244
 
Name Accession Description Interval E-value
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 1-256 1.36e-89

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 266.25  E-value: 1.36e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   1 MAAYSVDLPlksIMTQLSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLL 80
Cdd:cd13959   22 LAAGGLPLP---LLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVKEALLFLAVQLLLGLALLL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  81 LTSPTAGLVGLLGIFpLHALYPLMKRWTWWPQAWLGLAMNWGYPVAWLSITTLNLPVVATFFCGTICWSIFYDTIYACQD 160
Cdd:cd13959   99 QLNPLTILLSPIALL-LVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYLAVIFWTAGYDTIYAHQD 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 161 REDDVKAGVGSTAVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYVVScgGGAIHMCWQLLSWDMKLP-SSCLAKF 239
Cdd:cd13959  178 REDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGL--GAAAHLLWQEHRLDLPDPlRSCLAFF 255

                        250
                 ....*....|....*..
gi 597938946 240 RSNGDLGYILLAGMLLD 256
Cdd:cd13959  256 LSNGWVGLLLFAGLLLD 272
ubiA_proteo TIGR01474
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ...
 1-256 6.46e-70

4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 130539  Cd Length: 281  Bit Score: 216.42  E-value: 6.46e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946    1 MAAYSVDLPLKSImtqLSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLL 80
Cdd:TIGR01474  29 LAAQAGGIPPLYL---LGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLASGAVSVRQAILFLLVQLLVALGVLL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   81 LTSPTAGLVGLLGIFPLhALYPLMKRWTWWPQAWLGLAMNWGYPVAWLSITTlNLPVVA-TFFCGTICWSIFYDTIYACQ 159
Cdd:TIGR01474 106 QLNPLTILLGVASLALV-ATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTG-DLSTAAwVLYLANILWTLGYDTIYAMQ 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  160 DREDDVKAGVGSTAVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYvVSCGGGAIHMCWQLLSWDMKLPSSCLAKF 239
Cdd:TIGR01474 184 DKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYY-LGLAAAALLLIRQIATLDIRDPENCLKLF 262

                         250
                  ....*....|....*..
gi 597938946  240 RSNGDLGYILLAGMLLD 256
Cdd:TIGR01474 263 KANNYVGLLLFAGIALG 279
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
 14-255 3.21e-61

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 194.52  E-value: 3.21e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  14 MTQLSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLG 93
Cdd:PLN02809  44 LKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASS 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  94 IFpLHALYPLMKRWTWWPQAWLGLAMNWGYPVAWLSIT-TLNLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGST 172
Cdd:PLN02809 124 LL-LVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKgSLDPAVVLPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKST 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 173 AVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYvVSCGGGAIHMCWQLLSWDMKLPSSCLAKFRSNGDLGYILLAG 252
Cdd:PLN02809 203 ALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYY-AGLAAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAG 281


                 ...
gi 597938946 253 MLL 255
Cdd:PLN02809 282 IVL 284
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 21-255 2.28e-53

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 174.26  E-value: 2.28e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  21 AIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFpLHAL 100
Cdd:COG0382   43 VLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGRISLREALLLAIVLLLLALALALLLNPLTFLLALAALA-LAWA 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 101 YPL-MKRWTWWPQAWLGLAMNWGYPVAWLSITTLNLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFGSW 179
Cdd:COG0382  122 YSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPLSAWLLALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVR 201

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 597938946 180 IRPILTG-FATTFIACVVYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSWD--MKLPSSCLAKFRSNGDLGYILLAGMLL 255
Cdd:COG0382  202 DALIIAGvLYALAVLLLLLLGLLAGLGLLYLLGLLAALLLLYLSQLWLLRprKKDPARALKLFKLNMLLGLLLFLGIAL 280
UbiA pfam01040
UbiA prenyltransferase family;
21-239 4.08e-40

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 138.90  E-value: 4.08e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   21 AIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFpLHAL 100
Cdd:pfam01040  26 LLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALGLLLLLLLNPLTALLGLAALL-LYVL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  101 YPL-MKRWTWWPQAWLGLAMNWGYPVAWLSITTLNLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFGSW 179
Cdd:pfam01040 105 YTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIALANDLRDREDDRKAGIKTLPVVLGRK 184

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  180 IRPILTGFATTFIACVVYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSWDMKLPSSCLAKF 239
Cdd:pfam01040 185 AARILLALLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPKKDAKAF 244
ubiA PRK12873
4-hydroxybenzoate polyprenyltransferase;
17-255 1.32e-24

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 171787 [Multi-domain]  Cd Length: 294  Bit Score: 99.35  E-value: 1.32e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  17 LSMYAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIV-LTVAATSMLLLTSPTAGLVGLLGIF 95
Cdd:PRK12873  46 LLLIILGGLAVSGAGCIANDLWDRRIDRKVERTKNRPLARGKISLKTAYSLLIVlLLLSLFVVLSLPQPSRNLCLSLAFL 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  96 --PLHALYPLMKRWTWWPQAWLGLAmnWGYPV--AWLSIT-TLNL-PVVATFFCGTICWSIFYDTIYACQDREDDVKAGV 169
Cdd:PRK12873 126 alPPILIYPSAKRWFAYPQAILALC--WGFAVliPWAAAEgSLNGgWPLLFCWLATLLWTFGFDTVYAMADRRDDAKIGL 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 170 GSTAVLFGSWIRPilTGFATTFIACVV--YAGMLNGQGLAYYVVscgggaihmcWQLLSWDMKLpsSCLAKFRSNGD--- 244
Cdd:PRK12873 204 NSSALSLGSNALK--TVQICYFLTSIFlaLAAFIAQVGFIFWPF----------WLIASIGMQR--DILKLFPEKQSikt 269

                        250       260
                 ....*....|....*....|.
gi 597938946 245 ----------LGYILLAGMLL 255
Cdd:PRK12873 270 ignhfsnqviLGSLLLLGLIL 290
ubiA_other TIGR01475
putative 4-hydroxybenzoate polyprenyltransferase; A fairly deep split separates this ...
 27-258 2.82e-20

putative 4-hydroxybenzoate polyprenyltransferase; A fairly deep split separates this polyprenyltransferase subfamily from the set of mitochondrial and proteobacterial 4-hydroxybenzoate polyprenyltransferases, described in TIGR01474. Protoheme IX farnesyltransferase (heme O synthase) (TIGR01473) is more distantly related. Because no species appears to have both this protein and a member of TIGR01474, it is likely that this model represents 4-hydroxybenzoate polyprenyltransferase, a critical enzyme of ubiquinone biosynthesis, in the Archaea, Gram-positive bacteria, Aquifex aeolicus, the Chlamydias, etc. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273646  Cd Length: 282  Bit Score: 87.40  E-value: 2.82e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   27 LHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFPLhALYPLMKR 106
Cdd:TIGR01475  48 ARTAAMAFNRIIDRAIDARNPRTKNRPLVSGLISKKEARTMIILSLALFLSASYFLNPLAFILSPLVLLVL-IIYPYTKR 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  107 WTWWPQAWLGLAMNWGYPVAWLSITTL--NLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFGS-WIRPI 183
Cdd:TIGR01475 127 FTFLCHYVLGSTYGLAPLAGWVAVIGTisFFLVAWLLGIGVGFWIAGFDLIYAIQDYEFDRKNGLHSIPARFGIkAALKI 206

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 597938946  184 LTGFATTFIACVVYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSWDMKLPSSCLAKFRSNGDLGYILLAGMLLDCY 258
Cdd:TIGR01475 207 ASLSHVITFILLLLVGFYVGNGYIALLALILIGLILAYEHYIVDPGDQSKIQRAFFYANGFLSITFLIGVIIDVL 281
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 1-110 1.43e-16

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 77.09  E-value: 1.43e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   1 MAAYSVDLPLKSIMTqlsmyAIGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSML- 79
Cdd:cd13957   22 LAPGGVPDLLLLLLT-----LLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHALIFGLVLGILGLALLa 96

                         90       100       110
                 ....*....|....*....|....*....|..
gi 597938946  80 LLTSPTAGLVGLLGIFPLHALY-PLMKRWTWW 110
Cdd:cd13957   97 LFVNPLTALLGLLGIFLYVFVYtPLKKRTTPL 128
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
 22-110 5.71e-16

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 75.55  E-value: 5.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  22 IGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSML-LLTSPTAGLVGLLGIFplhaL 100
Cdd:COG0109   57 LGGALAAGAANALNNYIDRDIDALMKRTKNRPLPTGRISPREALIFGLVLGVLGLALLaLFVNPLAALLGLLGIF----F 132

                         90
                 ....*....|....*
gi 597938946 101 Y-----PLMKRWTWW 110
Cdd:COG0109  133 YvvvytLWLKRRTPQ 147
ubiA PRK13106
prenyltransferase; Reviewed
 27-227 1.80e-15

prenyltransferase; Reviewed


Pssm-ID: 237283  Cd Length: 300  Bit Score: 74.38  E-value: 1.80e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  27 LHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVA--ATSML-----LLTSPTAGLVGLlgifplha 99
Cdd:PRK13106  61 LRTAGMTNDNLADLEIDAKNPRTKNRPLVTGAIKISEAKALITAGLILffASAYLvnrwaLLLSPIVALIAM-------- 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 100 LYPLMKRWTWWPQAWLGLAMN---WGYPVAWL-----SITTLNLPVVATFFCGTICWSIFYDTIYACQDREDDVKAGVGS 171
Cdd:PRK13106 133 SYPYMKRYTAFANYHLASIQGlavFSGAVAVLglyanSLIQVLLRVPWLFVIGTILWAAGFDLYNHIPDAEFDREMGLHS 212

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 597938946 172 TAVLFGSWIRPILTGFATTFIACVVYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSW 227
Cdd:PRK13106 213 FAVVLGKWALTFAGLNQLFSVVLDLLGDLYYGLGPIAIAATILHGLIMAYAYYLAS 268
ubiA PRK12888
4-hydroxybenzoate octaprenyltransferase;
27-177 7.53e-15

4-hydroxybenzoate octaprenyltransferase;


Pssm-ID: 183814  Cd Length: 284  Bit Score: 72.45  E-value: 7.53e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  27 LHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFPLhALYPLMKR 106
Cdd:PRK12888  51 ARTFAMAANRIIDREIDARNPRTAGRELVTGAVSVRTAWTGALVALAVFLGAAALLNPLCLALAPLAVAPL-VVYPYAKR 129

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 597938946 107 WTWWPQAWLGLAMNWGYPVAWLSIT-TLNLPVVaTFFCGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFG 177
Cdd:PRK12888 130 FTNFPHAILGLAQAVGPVGAWIAVTgTWSWPAV-LLGLAVGLWIGGFDLIYACQDAEVDRRIGVRSVPARFG 200
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 22-110 1.97e-14

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 71.32  E-value: 1.97e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  22 IGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSML-LLTSPTAGLVGLLGIFPLHAL 100
Cdd:PRK04375  51 LGIALVAGAAGALNNYIDRDIDAKMERTKNRPLVTGRISPREALIFGLVLGVLGFLLLgLFVNPLAAWLTLAGIFFYVVV 130

                         90
                 ....*....|.
gi 597938946 101 YPL-MKRWTWW 110
Cdd:PRK04375 131 YTLwLKRRTPQ 141
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 21-255 2.41e-14

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 70.84  E-value: 2.41e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  21 AIGSTLLHSAACVINDICDVDFDRqvERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFpLHAL 100
Cdd:cd13956   38 LLAVFLGAGAGYALNDYTDRELDA--INKPDRPLPSGRLSPRQALAFAAALLLVGLALALALGPLALLLLLAGLL-LGLA 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 101 YPLMKRWTWWPQ-AWLGLAMNWGYPVAWLSITTLNLP----VVATFFCGTICWSIFYDTIyacQDREDDVKAGVGSTAVL 175
Cdd:cd13956  115 YSLGLKRLKLGGwGVLGYATGLALLPGLGAVAAGGLVplalLLALVFLLLGLGINLYNDL---PDVEGDRAAGIRTLPVR 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 176 FGswIRPILTGFATTFIACVVYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSWDMKLPSSCLAKFRSNGDLGYILLAGMLL 255
Cdd:cd13956  192 LG--PRRARRLAAGLLLAALILVVLLAVAGLLGPLALLALLAVALLALRARFARADRLPALPRGFLLLAVYRLLLFAALL 269
ubiA PRK12886
prenyltransferase; Reviewed
 29-261 6.13e-14

prenyltransferase; Reviewed


Pssm-ID: 237247  Cd Length: 291  Bit Score: 70.10  E-value: 6.13e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  29 SAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFlIVLTVA----ATSMLlltSPTAGLVGLLGIFPLhALYPLM 104
Cdd:PRK12886  56 TAAMGFNRLIDAEIDARNPRTAGRAIPAGLISKGSAILF-IVLSSLlmlfAAWFL---NPLCLYLSPPALFFL-LLYSYC 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 105 KRWTWWPQAWLGLAMNWGYPVAWLSIT-TLNLPVVaTFFCGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFGS----W 179
Cdd:PRK12886 131 KRFTALAHVVLGFCLALAPLGAWIAIRgTIELPAI-LLGLAVLFWVAGFDILYALQDLEFDRKEGLHSIPAKLGVngslW 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 180 IRPILTGFATTFIAcvvYAGMLNGQGLAYYVVSCGGGAIHMCWQLLSWDMKLPSSCLAKFRSNGDLGYILLAGMLLDCYI 259
Cdd:PRK12886 210 IARVFHLLMIGFLF---ALGISAGLGPWFLAGLAVTGILLLYEHWLLRGGDLTRLDAAFFNMNGYISVTLFAATLFDRLF 286


                 ..
gi 597938946 260 RR 261
Cdd:PRK12886 287 YF 288
PT_UbiA_2 cd13963
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 26-101 7.76e-08

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260126  Cd Length: 278  Bit Score: 52.09  E-value: 7.76e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597938946  26 LLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVgLLGIFPLHALY 101
Cdd:cd13963   44 LAASAVYILNDLLDLEADRLHPTKRNRPIASGRLSIPAALALAVVLLLAGLALALLLSPAFLLV-LLAYLVLNLAY 118
PRK12324 PRK12324
decaprenyl-phosphate phosphoribosyltransferase;
26-89 1.01e-07

decaprenyl-phosphate phosphoribosyltransferase;


Pssm-ID: 237058  Cd Length: 295  Bit Score: 51.79  E-value: 1.01e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 597938946  26 LLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLV 89
Cdd:PRK12324  57 LASSAVYLVNDIRDVEADRLHPTKRNRPIASGVVSVSLAYILAVVLLVASLALAYLLSPKLALV 120
PT_UbiA_1 cd13964
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 21-92 1.64e-07

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260127  Cd Length: 282  Bit Score: 51.04  E-value: 1.64e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 597938946  21 AIGSTLLHSAACVINDICDVDFDRqVERTKsRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLL 92
Cdd:cd13964   38 LLASVLLYAAGMVLNDVFDAELDA-RERPE-RPIPSGRVSRGAALALGAGLLAAGVALAALVGRLSGLVALL 107
PLN02776 PLN02776
prenyltransferase
 22-116 3.53e-07

prenyltransferase


Pssm-ID: 215415  Cd Length: 341  Bit Score: 50.51  E-value: 3.53e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  22 IGSTLLHSAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLL-TSPTAGLVGLLGIFPLHAL 100
Cdd:PLN02776  36 AGTMLCAASANTLNQVFEVKNDSKMKRTMRRPLPSGRISVPHAVAWAVVVGAAGVALLAYkTNMLTAGLGAGNILLYAFV 115

                         90
                 ....*....|....*.
gi 597938946 101 YPLMKRWTWWpQAWLG 116
Cdd:PLN02776 116 YTPLKQIHPA-NTWVG 130
PT_UbiA_DGGGPS cd13961
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ...
 1-213 9.69e-07

Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260124  Cd Length: 270  Bit Score: 48.65  E-value: 9.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946   1 MAAYSVDLPLKSIMTQLSMYAIGSTLLHSAA-CVINDICDVDFDRqVERTKsRPLPAGIISIREATTFLIVLTVAATSML 79
Cdd:cd13961   20 LGALFALGPLLSLNDLELLLLFLSVFLIAAAgYIINDYFDVEIDR-INKPD-RPIPSGRISRREALILSILLNALGLILA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  80 LLTSPTAGLVGLLGIFPLHALYPLMKRwtwwpQAWLGLAMnwgypVAWLSITTlnlPVVATFFCGTICWSIFYDTIYA-- 157
Cdd:cd13961   98 FLLSPLALLIALLNSLLLWLYSHKLKR-----TPLIGNLL-----VALLTGLP---FLFGGLAAGNLLLIILLLALFAfl 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 597938946 158 ----------CQDREDDVKAGVGSTAVLFGswIRP---ILTGFATTFIACVVYAGMLNGQGLAYYVVSC 213
Cdd:cd13961  165 itlgreivkdIEDVEGDRAEGARTLPIVYG--IKKakkIAALLLLLAILLSPLPYLLGGLGILYLILII 231
ubiA PRK12876
prenyltransferase; Reviewed
 33-177 1.27e-05

prenyltransferase; Reviewed


Pssm-ID: 237244  Cd Length: 300  Bit Score: 45.51  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  33 VINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFpLHALYPLMKRWTWWPQ 112
Cdd:PRK12876  65 IVNQIIDCAIDKKNPRTSSRVLPAKLLSINFSMLLLTLCSFLFLSLCWLLNPLCFSLAVLSTL-LMIIYPYTKRVTFLCH 143

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 597938946 113 AWLGLAmnwgYPVAWLS--ITTLNLPVVATFFCGTICWSIFY-------DTIYACQDREDDVKAGVGSTAVLFG 177
Cdd:PRK12876 144 WILGLV----YYLAILMnfFAIIETPLSFSLFCMASLWGISFgmiiaanDIIYAIQDLEFDRKEGLFSIPARFG 213
PRK08238 PRK08238
UbiA family prenyltransferase;
29-109 1.98e-05

UbiA family prenyltransferase;


Pssm-ID: 236195 [Multi-domain]  Cd Length: 479  Bit Score: 45.25  E-value: 1.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  29 SAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVgLLGIFPLHALYPL-MKRW 107
Cdd:PRK08238 240 SAVYILNDLLDLEADRAHPRKRRRPFASGALPIPFGLAAAPLLLLAGLALALALGPAFLLV-LLAYLALTLAYSLrLKRK 318


                 ..
gi 597938946 108 TW 109
Cdd:PRK08238 319 VL 320
ubiA PRK12884
prenyltransferase; Reviewed
 21-92 2.33e-05

prenyltransferase; Reviewed


Pssm-ID: 183812  Cd Length: 279  Bit Score: 44.56  E-value: 2.33e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 597938946  21 AIGSTLLHSAACVINDICDVDFDRqVERTkSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLL 92
Cdd:PRK12884  43 FLTAFFASGSANALNDYFDYEVDR-INRP-DRPIPSGRISRREALLLAILLFILGLIAAYLISPLAFLVVIL 112
ubiA PRK12874
4-hydroxybenzoate polyprenyltransferase;
31-256 2.45e-05

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 237242  Cd Length: 291  Bit Score: 44.61  E-value: 2.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  31 ACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFPLhALYPLMKRWTWW 110
Cdd:PRK12874  63 AMAFNRLVDRDIDKDNPRTANRPSVDGRISVKSMVLFIVLNALIFIGVSYFINPLAFKLSFPFLIVL-GGYSYFKRFSSL 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946 111 PQAWLGLAMNWGyPVAWLSITTLNLPVVATFFC-GTICWSIFYDTIYACQDREDDVKAGVGSTAVLFGS----WIRPILT 185
Cdd:PRK12874 142 AHLVLGLSLGLA-PIAGVVAVLGEIPLWSVFLAlGVMFWVAGFDLLYSLQDMEFDKKRGLHSIPSKFGEkatlFISRLFH 220

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 597938946 186 GFATTFIACVVYAGmlNGQGLAYyvvscggGAIHMCWQLLSWDMKLPSSCLAK-----FRSNGDLGYILLAGMLLD 256
Cdd:PRK12874 221 LLAVLFWLLFVWCA--HLGLFAY-------LGVIVSALILLYEHYLVRKDFKKidkafFTLNGYLGIVFFIFIVLD 287
PRK09573 PRK09573
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
 33-97 2.33e-04

(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed


Pssm-ID: 181963  Cd Length: 279  Bit Score: 41.48  E-value: 2.33e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 597938946  33 VINDICDVDFDRQveRTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFPL 97
Cdd:PRK09573  55 VINDIYDIEIDKI--NKPERPIPSGRISLKEAKIFSITLFIVGLILSIFINIYAFLIALLNSILL 117
ubiA PRK12895
prenyltransferase; Reviewed
 29-177 5.49e-04

prenyltransferase; Reviewed


Pssm-ID: 237251  Cd Length: 286  Bit Score: 40.57  E-value: 5.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  29 SAACVINDICDVDFDRQVERTKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFpLHALYPLMKRWT 108
Cdd:PRK12895  51 TSAMSINRIEGLRYDMINPRKKDWALVSGRIKMREAIAFTIIFIAIFEICTFLLNRLVFILSPIVIF-LFIIDPFLKRYT 129

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 597938946 109 WWPQAWLGLAMNWGYPVAWLSIT---TLNLPVVATFFcGTICWSIFYDTIYACQDREDDVKAGVGSTAVLFG 177
Cdd:PRK12895 130 AWRHIYMGSIIGLGVLAGYLAVIpafPYNLLIYIIFI-SSSLWIAGFDIIYVIPDIEYDKINGLKTIMNTYG 200
ubiA PRK12882
prenyltransferase; Reviewed
 21-92 7.55e-04

prenyltransferase; Reviewed


Pssm-ID: 183811  Cd Length: 276  Bit Score: 39.96  E-value: 7.55e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 597938946  21 AIGSTLLHSAAC-VINDICDVDFDRqVERtKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLL 92
Cdd:PRK12882  43 AFAAVFLATGAGnAINDYFDREIDR-INR-PDRPIPSGAVSPRGALAFSILLFAAGVALAFLLPPLCLAIALF 113
PT_UbiA_chlorophyll cd13958
Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of ...
 33-118 7.84e-04

Bacteriochlorophyll/chlorophyll synthetase; Chlorophyll synthase catalyzes the last step of chlorophyll (Chl) biosynthesis, the addition of the tetraprenyl (phytyl or geranylgeranyl) side chain. In plant chloroplast, the chlorophyll synthase is located in thylakoid membrane and has been shown to also have a regulatory or channeling function. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260121  Cd Length: 277  Bit Score: 39.91  E-value: 7.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  33 VINDICDVDFDRQVERTksRPLPAGIISIREATTFLIVLTVAATSM-LLLTSPTAGLVGLLGIFpLHALY---PL-MKRW 107
Cdd:cd13958   54 TINDYYDREVDAINEPY--RPIPSGRISEREALWNIWVLLLLSLLVaLFLDGPWVFAAAVVGLV-LAYIYsapPLkLKQN 130

                         90
                 ....*....|.
gi 597938946 108 TWWPQAWLGLA 118
Cdd:cd13958  131 GWWGNAAVGLS 141
PRK07566 PRK07566
chlorophyll synthase ChlG;
33-118 8.81e-04

chlorophyll synthase ChlG;


Pssm-ID: 236052  Cd Length: 314  Bit Score: 39.91  E-value: 8.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  33 VINDICDVDFDRQVErtKSRPLPAGIISIREATTFLIVLTVAATSMLLLTSPTAGLVGLLGIFPLHAlY---PL-MKRWT 108
Cdd:PRK07566  83 TLNDYFDREVDAINE--PYRPIPSGAISLRWVLYLIAVLTVLGLAVAYLLGPWVFLAALLGLFLAWI-YsapPLrLKQNG 159

                         90
                 ....*....|
gi 597938946 109 WWPQAWLGLA 118
Cdd:PRK07566 160 WLGNYAVGLS 169
ubiA PRK05951
prenyltransferase; Reviewed
 23-177 1.43e-03

prenyltransferase; Reviewed


Pssm-ID: 180323  Cd Length: 296  Bit Score: 39.38  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  23 GSTLLHSAACVINDICDVDFDRQVERT---KSRPLPAGIISIREATTFLIVLTVAAT----SMLLLTSPTAGLVGLLGIF 95
Cdd:PRK05951  48 GYFLLHASLNVFNDYKDYVLDCDHHETtgyRQHPIQAGIMTLGHLRVLGIALGAIALqlgwSLVLDRGIGAVTLALLGVF 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 597938946  96 PLHAL----YPLMKRW--------TWWPQAWLGLAMNWGYPVAWLSITT---LNLPVVATFFCGTicwsifydtiyaCQD 160
Cdd:PRK05951 128 LWTCYmgppFFLKYRWlgehlvfyAWSHMLVMGLIYVWLGNLSSPNLLAgvpLGLLMALVLLSNN------------LRD 195

                        170
                 ....*....|....*..
gi 597938946 161 REDDVKAGVGSTAVLFG 177
Cdd:PRK05951 196 IEDDERKGIPTLAVIFG 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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