NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2274689911|ref|XP_007244091|]
View 

diphosphomevalonate decarboxylase [Astyanax mexicanus]

Protein Classification

diphosphomevalonate/mevalonate 3,5-bisphosphate decarboxylase family protein( domain architecture ID 706585)

diphosphomevalonate/mevalonate 3,5-bisphosphate decarboxylase family protein similar to diphosphomevalonate decarboxylase (DMD) that catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP), and mevalonate 3,5-bisphosphate decarboxylase (MBD) that catalyzes the ATP-independent decarboxylation of (R)-mevalonate 3,5-bisphosphate to isopentenyl phosphate

EC:  4.1.1.-
Gene Ontology:  GO:0016831|GO:0008299
PubMed:  8382990|7947744|31268677

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MDD_C super family cl28577
Mevalonate 5-diphosphate decarboxylase C-terminal domain; Mevalonate diphosphate decarboxylase ...
 16-344 9.63e-168

Mevalonate 5-diphosphate decarboxylase C-terminal domain; Mevalonate diphosphate decarboxylase (EC:4.1.1.33) catalyzes the ATP dependent decarboxylation of mevalonate 5-diphosphate (MVAPP) to form isopentenyl 5-diphosphate. The reaction is required for production of polyisoprenoids and sterols from acetyl-CoA. This entry represents the C-terminal domain of the mevalonate 5-diphosphate decarboxylase enzyme which is a member of the GHMP kinase superfamily.


The actual alignment was detected with superfamily member PLN02407:

Pssm-ID: 475042  Cd Length: 343  Bit Score: 473.12  E-value: 9.63e-168
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  16 TCTAPVNIAVIKYWGKRDEELILPINSSLSVTLHQDQLKTTTTVACSRSFQEDRIWLNGKEEDINQPRLQSCLREIRRLA 95
Cdd:PLN02407    5 TAQAPTNIAVIKYWGKRDEKLILPINSSISVTLDPDHLCATTTVAVSPSFDQDRLWLNGKEISLSGGRYQNCLREIRARA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  96 RKrrsDDDPSNDISLSHR------VHICSVNNFPTAAGLASSAAGYACLVYSLSRLFGV----EGELSGVARQGSGSACR 165
Cdd:PLN02407   85 TD---VEDEEKGIKITKKdweklhVHIASYNNFPTAAGLASSAAGFACLVFALAKLMNVkedfPGELSAIARQGSGSACR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 166 SMYGGFVQWKMGEREDGKDSLAEQVAAESHWPELRVLVLVVSAERKPVGSTSGMQTSVKTSQLLKHRADSVVPGRMEEMI 245
Cdd:PLN02407  162 SLYGGFVKWNMGKKEDGSDSIAVQLADEKHWDDLVIIIAVVSSRQKETSSTSGMRESVETSPLLQHRAKEVVPKRILQME 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 246 SAIQKRDFATFAELTMKDSNQFHATCLDTYPPIFYLNDISRRVISLVHRYNQHYQETRVAYTFDAGPNAVIYTLQEHVPE 325
Cdd:PLN02407  242 EAIKNRDFASFAKLTCADSNQFHATCLDTSPPIFYMNDTSRRIISLVEKWNRSEGTPQVAYTFDAGPNAVLIALNRKVAA 321

                         330       340
                  ....*....|....*....|..
gi 2274689911 326 FV-QAVRHFFPP--ETNGGEFV 344
Cdd:PLN02407  322 QLlQRLLYYFPPssDTDLSSYV 343
 
Name Accession Description Interval E-value
PLN02407 PLN02407
diphosphomevalonate decarboxylase
 16-344 9.63e-168

diphosphomevalonate decarboxylase


Pssm-ID: 178029  Cd Length: 343  Bit Score: 473.12  E-value: 9.63e-168
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  16 TCTAPVNIAVIKYWGKRDEELILPINSSLSVTLHQDQLKTTTTVACSRSFQEDRIWLNGKEEDINQPRLQSCLREIRRLA 95
Cdd:PLN02407    5 TAQAPTNIAVIKYWGKRDEKLILPINSSISVTLDPDHLCATTTVAVSPSFDQDRLWLNGKEISLSGGRYQNCLREIRARA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  96 RKrrsDDDPSNDISLSHR------VHICSVNNFPTAAGLASSAAGYACLVYSLSRLFGV----EGELSGVARQGSGSACR 165
Cdd:PLN02407   85 TD---VEDEEKGIKITKKdweklhVHIASYNNFPTAAGLASSAAGFACLVFALAKLMNVkedfPGELSAIARQGSGSACR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 166 SMYGGFVQWKMGEREDGKDSLAEQVAAESHWPELRVLVLVVSAERKPVGSTSGMQTSVKTSQLLKHRADSVVPGRMEEMI 245
Cdd:PLN02407  162 SLYGGFVKWNMGKKEDGSDSIAVQLADEKHWDDLVIIIAVVSSRQKETSSTSGMRESVETSPLLQHRAKEVVPKRILQME 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 246 SAIQKRDFATFAELTMKDSNQFHATCLDTYPPIFYLNDISRRVISLVHRYNQHYQETRVAYTFDAGPNAVIYTLQEHVPE 325
Cdd:PLN02407  242 EAIKNRDFASFAKLTCADSNQFHATCLDTSPPIFYMNDTSRRIISLVEKWNRSEGTPQVAYTFDAGPNAVLIALNRKVAA 321

                         330       340
                  ....*....|....*....|..
gi 2274689911 326 FV-QAVRHFFPP--ETNGGEFV 344
Cdd:PLN02407  322 QLlQRLLYYFPPssDTDLSSYV 343
MDD_C pfam18376
Mevalonate 5-diphosphate decarboxylase C-terminal domain; Mevalonate diphosphate decarboxylase ...
 201-386 5.15e-123

Mevalonate 5-diphosphate decarboxylase C-terminal domain; Mevalonate diphosphate decarboxylase (EC:4.1.1.33) catalyzes the ATP dependent decarboxylation of mevalonate 5-diphosphate (MVAPP) to form isopentenyl 5-diphosphate. The reaction is required for production of polyisoprenoids and sterols from acetyl-CoA. This entry represents the C-terminal domain of the mevalonate 5-diphosphate decarboxylase enzyme which is a member of the GHMP kinase superfamily.


Pssm-ID: 465732  Cd Length: 186  Bit Score: 353.40  E-value: 5.15e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 201 VLVLVVSAERKPVGSTSGMQTSVKTSQLLKHRADSVVPGRMEEMISAIQKRDFATFAELTMKDSNQFHATCLDTYPPIFY 280
Cdd:pfam18376   1 VLILVVSDEKKEVSSTSGMQRSVETSPLLKHRAEHVVPERMEAMEKAILAKDFETFAEITMKDSNQFHAVCLDTYPPIFY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 281 LNDISRRVISLVHRYNQHYQETRVAYTFDAGPNAVIYTLQEHVPEFVQAVRHFFPPETNGGEFVKGLSVDSASLSEELKR 360
Cdd:pfam18376  81 LNDTSRAIIQLVHAYNEFAGRIKVAYTFDAGPNAVLYLLEKDVPKVLSLLKHFFPPSTNGDQFFKGLPVLPSELSEELKA 160

                         170       180
                  ....*....|....*....|....*.
gi 2274689911 361 AIGMEPVPKGISYVISTQVGPGPCVV 386
Cdd:pfam18376 161 SLAMKPIPGGVKYIIHTKVGDGPRVL 186
mevDPdecarb TIGR01240
diphosphomevalonate decarboxylase; This enzyme catalyzes the last step in the synthesis of ...
 15-325 7.63e-97

diphosphomevalonate decarboxylase; This enzyme catalyzes the last step in the synthesis of isopentenyl diphosphate (IPP) in the mevalonate pathway. Alternate names: mevalonate diphosphate decarboxylase; pyrophosphomevalonate decarboxylase [Central intermediary metabolism, Other]


Pssm-ID: 130307  Cd Length: 305  Bit Score: 291.47  E-value: 7.63e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  15 ITCTAPVNIAVIKYWGKRDEELILPINSSLSVTLhqDQLKTTTTVACSRSFQEDRIWLNGKEE-DINQPRLQSCLREIRR 93
Cdd:TIGR01240   1 ASVTAYVNIATIKYWGKRNTKLNLPTNSSISLTL--SQLRTLTSVAFADEFERDTFYLNGTLQhSIDNEKTSNCLDDFRQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  94 LARkrrsdddpsndisLSHRVHICSVNNFPTAAGLASSAAGYACLVYSLSRLFGV---EGELSGVARQGSGSACRSMYGG 170
Cdd:TIGR01240  79 LRK-------------EQEKLHIVSQNNFPTAAGLASSASGLAALVSACAKLYQLpldTSELSRIARKGSGSACRSLFGG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 171 FVQWKMGEreDGKDSLAEQVAAESHWPELRVLVLVVSAERKPVGSTSGMQTSVKTSQLLKHRADSVVPgRMEEMISAIQK 250
Cdd:TIGR01240 146 YVAWEKGK--DDHSSAAVQVADDSDWPQ*AMCVLVVNDIKKDVSSRQGMQLTVATSELFKEWIEHVVP-DFEV*RKAIKT 222

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2274689911 251 RDFATFAELTMKDSNQFHATCLDTYPPIFYLNDISRRVISLVHRYNQhyQETRVAYTFDAGPNAVIYTLQEHVPE 325
Cdd:TIGR01240 223 KDFATFGKETEANSLSMHATTLDAFPPFFYLNDTSKRAMSAVHTLRQ--GGTICYFTMDAGPNVKVLYLAENLSK 295
MVD1 COG3407
Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]; Mevalonate ...
 15-335 1.59e-88

Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]; Mevalonate pyrophosphate decarboxylase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 442633  Cd Length: 322  Bit Score: 270.91  E-value: 1.59e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  15 ITCTAPVNIAVIKYWGKRDEELILPINSSLSVTLhqDQLKTTTTVACSRSFQEDRIWLNGKEEDINQ-PRLQSCLREIRR 93
Cdd:COG3407     6 ATARAHSNIALIKYWGKRDEELNLPANPSLSLTL--DAFYTTTTVEFDKDLAEDEFILNGEPQKGKFlPKISKFLDRVRA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  94 LARKrrsdddpsndislSHRVHICSVNNFPTAAGLASSAAGYACLVYSLSRLFGVEG---ELSGVARQGSGSACRSMYGG 170
Cdd:COG3407    84 LAGK-------------SYHARIESENNFPTAAGLASSASGFAALALAANSAEGLDLddrKLSRLARLGSGSACRSIFGG 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 171 FVQWKMGEREDgkDSLAEQVAAEsHWPeLRVLVLVVSAERKPVGSTSGMQTsVKTSQLLKHRADSvVPGRMEEMISAIQK 250
Cdd:COG3407   151 FVEWGKGEDDE--DSYAVPIPAE-DWD-LADIILVVDKGEKKVSSREGMKT-AETSPFYPAWVEQ-AEEDLEKLKEAIKA 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 251 RDFATFAELTMKDSNQFHATCLDTYPPIFYLNDISRRVISLVHRYNQhyQETRVAYTFDAGPNAVIYTLQEHVPEFVQAV 330
Cdd:COG3407   225 GDFEALGEIAESNALRMHATMMTSNPPFIYWKPNTLEVINAVRELRE--EGLPVYFTLDAGPNVKVLCPEEDAEKVAAFL 302


                  ....*
gi 2274689911 331 RHFFP 335
Cdd:COG3407   303 AAELV 307
 
Name Accession Description Interval E-value
PLN02407 PLN02407
diphosphomevalonate decarboxylase
 16-344 9.63e-168

diphosphomevalonate decarboxylase


Pssm-ID: 178029  Cd Length: 343  Bit Score: 473.12  E-value: 9.63e-168
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  16 TCTAPVNIAVIKYWGKRDEELILPINSSLSVTLHQDQLKTTTTVACSRSFQEDRIWLNGKEEDINQPRLQSCLREIRRLA 95
Cdd:PLN02407    5 TAQAPTNIAVIKYWGKRDEKLILPINSSISVTLDPDHLCATTTVAVSPSFDQDRLWLNGKEISLSGGRYQNCLREIRARA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  96 RKrrsDDDPSNDISLSHR------VHICSVNNFPTAAGLASSAAGYACLVYSLSRLFGV----EGELSGVARQGSGSACR 165
Cdd:PLN02407   85 TD---VEDEEKGIKITKKdweklhVHIASYNNFPTAAGLASSAAGFACLVFALAKLMNVkedfPGELSAIARQGSGSACR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 166 SMYGGFVQWKMGEREDGKDSLAEQVAAESHWPELRVLVLVVSAERKPVGSTSGMQTSVKTSQLLKHRADSVVPGRMEEMI 245
Cdd:PLN02407  162 SLYGGFVKWNMGKKEDGSDSIAVQLADEKHWDDLVIIIAVVSSRQKETSSTSGMRESVETSPLLQHRAKEVVPKRILQME 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 246 SAIQKRDFATFAELTMKDSNQFHATCLDTYPPIFYLNDISRRVISLVHRYNQHYQETRVAYTFDAGPNAVIYTLQEHVPE 325
Cdd:PLN02407  242 EAIKNRDFASFAKLTCADSNQFHATCLDTSPPIFYMNDTSRRIISLVEKWNRSEGTPQVAYTFDAGPNAVLIALNRKVAA 321

                         330       340
                  ....*....|....*....|..
gi 2274689911 326 FV-QAVRHFFPP--ETNGGEFV 344
Cdd:PLN02407  322 QLlQRLLYYFPPssDTDLSSYV 343
MDD_C pfam18376
Mevalonate 5-diphosphate decarboxylase C-terminal domain; Mevalonate diphosphate decarboxylase ...
 201-386 5.15e-123

Mevalonate 5-diphosphate decarboxylase C-terminal domain; Mevalonate diphosphate decarboxylase (EC:4.1.1.33) catalyzes the ATP dependent decarboxylation of mevalonate 5-diphosphate (MVAPP) to form isopentenyl 5-diphosphate. The reaction is required for production of polyisoprenoids and sterols from acetyl-CoA. This entry represents the C-terminal domain of the mevalonate 5-diphosphate decarboxylase enzyme which is a member of the GHMP kinase superfamily.


Pssm-ID: 465732  Cd Length: 186  Bit Score: 353.40  E-value: 5.15e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 201 VLVLVVSAERKPVGSTSGMQTSVKTSQLLKHRADSVVPGRMEEMISAIQKRDFATFAELTMKDSNQFHATCLDTYPPIFY 280
Cdd:pfam18376   1 VLILVVSDEKKEVSSTSGMQRSVETSPLLKHRAEHVVPERMEAMEKAILAKDFETFAEITMKDSNQFHAVCLDTYPPIFY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 281 LNDISRRVISLVHRYNQHYQETRVAYTFDAGPNAVIYTLQEHVPEFVQAVRHFFPPETNGGEFVKGLSVDSASLSEELKR 360
Cdd:pfam18376  81 LNDTSRAIIQLVHAYNEFAGRIKVAYTFDAGPNAVLYLLEKDVPKVLSLLKHFFPPSTNGDQFFKGLPVLPSELSEELKA 160

                         170       180
                  ....*....|....*....|....*.
gi 2274689911 361 AIGMEPVPKGISYVISTQVGPGPCVV 386
Cdd:pfam18376 161 SLAMKPIPGGVKYIIHTKVGDGPRVL 186
mevDPdecarb TIGR01240
diphosphomevalonate decarboxylase; This enzyme catalyzes the last step in the synthesis of ...
 15-325 7.63e-97

diphosphomevalonate decarboxylase; This enzyme catalyzes the last step in the synthesis of isopentenyl diphosphate (IPP) in the mevalonate pathway. Alternate names: mevalonate diphosphate decarboxylase; pyrophosphomevalonate decarboxylase [Central intermediary metabolism, Other]


Pssm-ID: 130307  Cd Length: 305  Bit Score: 291.47  E-value: 7.63e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  15 ITCTAPVNIAVIKYWGKRDEELILPINSSLSVTLhqDQLKTTTTVACSRSFQEDRIWLNGKEE-DINQPRLQSCLREIRR 93
Cdd:TIGR01240   1 ASVTAYVNIATIKYWGKRNTKLNLPTNSSISLTL--SQLRTLTSVAFADEFERDTFYLNGTLQhSIDNEKTSNCLDDFRQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  94 LARkrrsdddpsndisLSHRVHICSVNNFPTAAGLASSAAGYACLVYSLSRLFGV---EGELSGVARQGSGSACRSMYGG 170
Cdd:TIGR01240  79 LRK-------------EQEKLHIVSQNNFPTAAGLASSASGLAALVSACAKLYQLpldTSELSRIARKGSGSACRSLFGG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 171 FVQWKMGEreDGKDSLAEQVAAESHWPELRVLVLVVSAERKPVGSTSGMQTSVKTSQLLKHRADSVVPgRMEEMISAIQK 250
Cdd:TIGR01240 146 YVAWEKGK--DDHSSAAVQVADDSDWPQ*AMCVLVVNDIKKDVSSRQGMQLTVATSELFKEWIEHVVP-DFEV*RKAIKT 222

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2274689911 251 RDFATFAELTMKDSNQFHATCLDTYPPIFYLNDISRRVISLVHRYNQhyQETRVAYTFDAGPNAVIYTLQEHVPE 325
Cdd:TIGR01240 223 KDFATFGKETEANSLSMHATTLDAFPPFFYLNDTSKRAMSAVHTLRQ--GGTICYFTMDAGPNVKVLYLAENLSK 295
MVD1 COG3407
Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]; Mevalonate ...
 15-335 1.59e-88

Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]; Mevalonate pyrophosphate decarboxylase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 442633  Cd Length: 322  Bit Score: 270.91  E-value: 1.59e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  15 ITCTAPVNIAVIKYWGKRDEELILPINSSLSVTLhqDQLKTTTTVACSRSFQEDRIWLNGKEEDINQ-PRLQSCLREIRR 93
Cdd:COG3407     6 ATARAHSNIALIKYWGKRDEELNLPANPSLSLTL--DAFYTTTTVEFDKDLAEDEFILNGEPQKGKFlPKISKFLDRVRA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911  94 LARKrrsdddpsndislSHRVHICSVNNFPTAAGLASSAAGYACLVYSLSRLFGVEG---ELSGVARQGSGSACRSMYGG 170
Cdd:COG3407    84 LAGK-------------SYHARIESENNFPTAAGLASSASGFAALALAANSAEGLDLddrKLSRLARLGSGSACRSIFGG 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 171 FVQWKMGEREDgkDSLAEQVAAEsHWPeLRVLVLVVSAERKPVGSTSGMQTsVKTSQLLKHRADSvVPGRMEEMISAIQK 250
Cdd:COG3407   151 FVEWGKGEDDE--DSYAVPIPAE-DWD-LADIILVVDKGEKKVSSREGMKT-AETSPFYPAWVEQ-AEEDLEKLKEAIKA 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2274689911 251 RDFATFAELTMKDSNQFHATCLDTYPPIFYLNDISRRVISLVHRYNQhyQETRVAYTFDAGPNAVIYTLQEHVPEFVQAV 330
Cdd:COG3407   225 GDFEALGEIAESNALRMHATMMTSNPPFIYWKPNTLEVINAVRELRE--EGLPVYFTLDAGPNVKVLCPEEDAEKVAAFL 302


                  ....*
gi 2274689911 331 RHFFP 335
Cdd:COG3407   303 AAELV 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH