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Conserved domains on  [gi|571539519|ref|XP_006601310|]
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probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4 isoform X1 [Glycine max]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02510 super family cl31891
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
7-379 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


The actual alignment was detected with superfamily member PLN02510:

Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 638.67  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519   7 VKSENRLKHRPLTPIRFLRGLIGLVVFLSTALMCLVYFVPVAVVGLRLFSIRCSRKTVSFIFGLWLSLWPSLFEKINKTK 86
Cdd:PLN02510   1 LESDSGPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  87 VVFSGDGVPMKERVLLIANHRTEVDWMYLWDLALRKGRLGCIKYILKSSLMKLPIFGWGFHILEFIAVERKWEIDEQILQ 166
Cdd:PLN02510  81 VVFSGDKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 167 QKLSTLKDPQDPLWLALFPEGTDYTDQKSKNSQKFAAEAGLPVLTNVLLPKTKGFHACLEALRASLDAVYDVTIAYKNQC 246
Cdd:PLN02510 161 QMLSSFKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRC 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 247 PSFLDNVFGVDPPEVHLHVRRIPVEEIPASETKAASWLIDTFQIKDQLLSDFKIQGHFPNQLNENEISTFKSLVSFMVIV 326
Cdd:PLN02510 241 PSFLDNVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVI 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 571539519 327 SFTAMFTYFTFFSVIWFKLYVGLSCAYLSLATRFNFQLMPLTYYVHALHKSKN 379
Cdd:PLN02510 321 ALTTVFTYLTLFSSVWFKIYVSLSCAYLTSATHFNWRPPPLIESLENSLKLVN 373
 
Name Accession Description Interval E-value
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
7-379 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 638.67  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519   7 VKSENRLKHRPLTPIRFLRGLIGLVVFLSTALMCLVYFVPVAVVGLRLFSIRCSRKTVSFIFGLWLSLWPSLFEKINKTK 86
Cdd:PLN02510   1 LESDSGPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  87 VVFSGDGVPMKERVLLIANHRTEVDWMYLWDLALRKGRLGCIKYILKSSLMKLPIFGWGFHILEFIAVERKWEIDEQILQ 166
Cdd:PLN02510  81 VVFSGDKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 167 QKLSTLKDPQDPLWLALFPEGTDYTDQKSKNSQKFAAEAGLPVLTNVLLPKTKGFHACLEALRASLDAVYDVTIAYKNQC 246
Cdd:PLN02510 161 QMLSSFKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRC 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 247 PSFLDNVFGVDPPEVHLHVRRIPVEEIPASETKAASWLIDTFQIKDQLLSDFKIQGHFPNQLNENEISTFKSLVSFMVIV 326
Cdd:PLN02510 241 PSFLDNVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVI 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 571539519 327 SFTAMFTYFTFFSVIWFKLYVGLSCAYLSLATRFNFQLMPLTYYVHALHKSKN 379
Cdd:PLN02510 321 ALTTVFTYLTLFSSVWFKIYVSLSCAYLTSATHFNWRPPPLIESLENSLKLVN 373
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
78-266 5.92e-81

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 246.00  E-value: 5.92e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  78 LFEKINKTKVVFSGDGVPM-KERVLLIANHRTEVDWMYLWDLALRKGRLGCIKYILKSSLMKLPIFGWGFHILEFIAVER 156
Cdd:cd07990    3 LFEWLSGVKVVVYGDEPKLpKERALIISNHRSEVDWLVLWMLADRFGRLGRLKIVLKDSLKYPPLGGWGWQLGEFIFLKR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 157 KWEIDEQILQQKLSTLKDPQDPLWLALFPEGTDYTDQKSKNSQKFAAEAGLPVLTNVLLPKTKGFHACLEALRASLDAVY 236
Cdd:cd07990   83 KWEKDEKTIKRQLKRLKDSPEPFWLLIFPEGTRFTEEKKERSQEFAEKNGLPPLKHVLLPRTKGFVAILETLRDAVDAVY 162
                        170       180       190
                 ....*....|....*....|....*....|.
gi 571539519 237 DVTIAYKNQCPSFL-DNVFGVDPPEVHLHVR 266
Cdd:cd07990  163 DVTIAYPDGKPPSEqRLLLGGKPREVHVHVR 193
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
100-210 1.20e-22

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 91.65  E-value: 1.20e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519   100 VLLIANHRTEVDWMYLWDLALRKGRlgCIKYILKSSLMKLPIFGWGFHILEFIAVERKWE-IDEQILQQKLSTLKDPQdp 178
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKLG--RVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGrKARAALREAVELLKEGE-- 76
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 571539519   179 lWLALFPEGTDYTDQK----SKNSQKFAAEAGLPVL 210
Cdd:smart00563  77 -WLLIFPEGTRSRPGKllpfKKGAARLALEAGVPIV 111
Acyltransf_C pfam16076
Acyltransferase C-terminus; This domain is found at the C-terminus of several different ...
258-324 7.63e-15

Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1.


Pssm-ID: 465006 [Multi-domain]  Cd Length: 74  Bit Score: 68.75  E-value: 7.63e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 571539519  258 PPEVHLHVRRIPVEEIPASETKAASWLIDTFQIKDQLLSDFKIQGHFPNQLNENEISTFKSLVSFMV 324
Cdd:pfam16076   7 PSEVHMYIRRIPLEELPEDEEELAQWLHDLFVEKDKLLDYFYETGTFFPGKEHIIPRRLKSLLVFIF 73
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
52-210 1.75e-14

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 71.96  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  52 LRLFSIRCSRKTVSFIFGLWLslwpslfeKINKTKVVFSG-DGVPMKERVLLIANHRTEVDWMYLWDLALRKgrlgcIKY 130
Cdd:COG0204    4 LFLLLRRFRYRLVRLWARLLL--------RLLGVRVRVEGlENLPADGPVLIVANHQSWLDILLLLAALPRP-----VRF 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 131 ILKSSLMKLPIFGWGFHILEFIAVER-KWEIDEQILQQKLSTLKDPQdplWLALFPEGTDYTDQKSKNSQK----FAAEA 205
Cdd:COG0204   71 VAKKELFKIPLLGWLLRALGAIPVDRsKRRAALRALRQAVEALKAGE---SLVIFPEGTRSPDGRLLPFKTgaarLALEA 147

                 ....*
gi 571539519 206 GLPVL 210
Cdd:COG0204  148 GVPIV 152
 
Name Accession Description Interval E-value
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
7-379 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 638.67  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519   7 VKSENRLKHRPLTPIRFLRGLIGLVVFLSTALMCLVYFVPVAVVGLRLFSIRCSRKTVSFIFGLWLSLWPSLFEKINKTK 86
Cdd:PLN02510   1 LESDSGPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  87 VVFSGDGVPMKERVLLIANHRTEVDWMYLWDLALRKGRLGCIKYILKSSLMKLPIFGWGFHILEFIAVERKWEIDEQILQ 166
Cdd:PLN02510  81 VVFSGDKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 167 QKLSTLKDPQDPLWLALFPEGTDYTDQKSKNSQKFAAEAGLPVLTNVLLPKTKGFHACLEALRASLDAVYDVTIAYKNQC 246
Cdd:PLN02510 161 QMLSSFKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRC 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 247 PSFLDNVFGVDPPEVHLHVRRIPVEEIPASETKAASWLIDTFQIKDQLLSDFKIQGHFPNQLNENEISTFKSLVSFMVIV 326
Cdd:PLN02510 241 PSFLDNVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVI 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 571539519 327 SFTAMFTYFTFFSVIWFKLYVGLSCAYLSLATRFNFQLMPLTYYVHALHKSKN 379
Cdd:PLN02510 321 ALTTVFTYLTLFSSVWFKIYVSLSCAYLTSATHFNWRPPPLIESLENSLKLVN 373
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
78-266 5.92e-81

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 246.00  E-value: 5.92e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  78 LFEKINKTKVVFSGDGVPM-KERVLLIANHRTEVDWMYLWDLALRKGRLGCIKYILKSSLMKLPIFGWGFHILEFIAVER 156
Cdd:cd07990    3 LFEWLSGVKVVVYGDEPKLpKERALIISNHRSEVDWLVLWMLADRFGRLGRLKIVLKDSLKYPPLGGWGWQLGEFIFLKR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 157 KWEIDEQILQQKLSTLKDPQDPLWLALFPEGTDYTDQKSKNSQKFAAEAGLPVLTNVLLPKTKGFHACLEALRASLDAVY 236
Cdd:cd07990   83 KWEKDEKTIKRQLKRLKDSPEPFWLLIFPEGTRFTEEKKERSQEFAEKNGLPPLKHVLLPRTKGFVAILETLRDAVDAVY 162
                        170       180       190
                 ....*....|....*....|....*....|.
gi 571539519 237 DVTIAYKNQCPSFL-DNVFGVDPPEVHLHVR 266
Cdd:cd07990  163 DVTIAYPDGKPPSEqRLLLGGKPREVHVHVR 193
PLN02380 PLN02380
1-acyl-sn-glycerol-3-phosphate acyltransferase
28-345 8.45e-60

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178006 [Multi-domain]  Cd Length: 376  Bit Score: 198.04  E-value: 8.45e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  28 IGLVVFLSTALMCLvyFVPVAVVGLRLFSIRCSRKTVSFIFG-LWLSL------WPSLFEKINKTKVVFSGDGvpmKERV 100
Cdd:PLN02380  12 LGLLFLLSGLIVNL--IQAVCFILVRPLSKSLYRRINRAVAElLWLELiwlvdwWAGVKVQLYADEETFELMG---KEHA 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 101 LLIANHRTEVDWMYLWDLALRKGRLGCIKYILKSSLMKLPIFGWGFHILEFIAVERKWEIDEQILQQKLSTLKDPQDPLW 180
Cdd:PLN02380  87 LVISNHRSDIDWLVGWILAQRSGCLGSALAVMKKSSKFLPVIGWSMWFSEYVFLERSWAKDENTLKSGFQRLKDFPRPFW 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 181 LALFPEGTDYTDQKSKNSQKFAAEAGLPVLTNVLLPKTKGFHACLEALRASLDAVYDVTIAY-KNQCPSFLDNVFGVDPP 259
Cdd:PLN02380 167 LALFVEGTRFTQAKLLAAQEYAASRGLPVPRNVLIPRTKGFVSAVSNMRSFVPAIYDVTVAVpKGQPAPTMLRIFRGQSS 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 260 EVHLHVRRIPVEEIPASETKAASWLIDTFQIKDQLLSDFKIQGHFPNQLNENEISTFKSLvsfMVIVSFTAMFTYFTFFS 339
Cdd:PLN02380 247 VVHVHIKRHSMKELPETDDGIAQWCKDVFVAKDALLDKHFAEDTFGDQEYQDIGRPKKSL---IVVISWACLLILGAIKF 323

                 ....*.
gi 571539519 340 VIWFKL 345
Cdd:PLN02380 324 LQWLSL 329
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
100-210 1.20e-22

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 91.65  E-value: 1.20e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519   100 VLLIANHRTEVDWMYLWDLALRKGRlgCIKYILKSSLMKLPIFGWGFHILEFIAVERKWE-IDEQILQQKLSTLKDPQdp 178
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKLG--RVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGrKARAALREAVELLKEGE-- 76
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 571539519   179 lWLALFPEGTDYTDQK----SKNSQKFAAEAGLPVL 210
Cdd:smart00563  77 -WLLIFPEGTRSRPGKllpfKKGAARLALEAGVPIV 111
PRK14014 PRK14014
putative acyltransferase; Provisional
21-303 2.88e-16

putative acyltransferase; Provisional


Pssm-ID: 237584 [Multi-domain]  Cd Length: 301  Bit Score: 78.35  E-value: 2.88e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  21 IRFLRG-LIGLVVFLSTALMCLVYFVPVAVVGL--RLFSIRCSRKTVSFIFGLWLSLWPS----LFEKINKTKVVFSGD- 92
Cdd:PRK14014   2 MNFLLApLRGLLSILLLILNTLFWSVPIIILGLlkLLLPIPAIRRACSRLLNFIAEAWISinnvILRLLPRTQWDVEGLe 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  93 GVPMKERVLLIANHRTEVDWMYLWDLALRKGRLgcIKYILKSSLMKLPIFGWGFHILEFIAVER--KweidEQILqqkls 170
Cdd:PRK14014  82 GLSKKGWYLVISNHQSWVDILVLQYVFNRRIPM--LKFFLKQELIWVPFLGLAWWALDFPFMKRysK----AYLA----- 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 171 tlKDP----QD--------------PLWLALFPEGTDYTDQK--SKNSQkfaaeaglpvLTNVLLPKTKGFHACLEALRA 230
Cdd:PRK14014 151 --KNPelkgKDlettrracekfkrmPTTIVNFVEGTRFTPEKhqQQQSP----------YQHLLKPKAGGIAFALNAMGE 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 231 SLDAVYDVTIAYKNQCPSFLDNVFGvDPPEVHLHVRRIPVEEIPA------SETKAA--SWLIDTFQIKDQLLSDFKIQG 302
Cdd:PRK14014 219 QFDGLLDVTIVYPDGRPSFWDLLSG-RVKKIVVHVRLLPIPEELIgdyfndKEFRRRfqQWLNQLWQEKDQLIEQLLAQY 297

                 .
gi 571539519 303 H 303
Cdd:PRK14014 298 N 298
Acyltransf_C pfam16076
Acyltransferase C-terminus; This domain is found at the C-terminus of several different ...
258-324 7.63e-15

Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1.


Pssm-ID: 465006 [Multi-domain]  Cd Length: 74  Bit Score: 68.75  E-value: 7.63e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 571539519  258 PPEVHLHVRRIPVEEIPASETKAASWLIDTFQIKDQLLSDFKIQGHFPNQLNENEISTFKSLVSFMV 324
Cdd:pfam16076   7 PSEVHMYIRRIPLEELPEDEEELAQWLHDLFVEKDKLLDYFYETGTFFPGKEHIIPRRLKSLLVFIF 73
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
52-210 1.75e-14

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 71.96  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  52 LRLFSIRCSRKTVSFIFGLWLslwpslfeKINKTKVVFSG-DGVPMKERVLLIANHRTEVDWMYLWDLALRKgrlgcIKY 130
Cdd:COG0204    4 LFLLLRRFRYRLVRLWARLLL--------RLLGVRVRVEGlENLPADGPVLIVANHQSWLDILLLLAALPRP-----VRF 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 131 ILKSSLMKLPIFGWGFHILEFIAVER-KWEIDEQILQQKLSTLKDPQdplWLALFPEGTDYTDQKSKNSQK----FAAEA 205
Cdd:COG0204   71 VAKKELFKIPLLGWLLRALGAIPVDRsKRRAALRALRQAVEALKAGE---SLVIFPEGTRSPDGRLLPFKTgaarLALEA 147

                 ....*
gi 571539519 206 GLPVL 210
Cdd:COG0204  148 GVPIV 152
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
94-211 5.99e-13

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 65.38  E-value: 5.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519   94 VPMKERVLLIANHRTEVDWMYLWdLALRKGRlGCIKYILKSSLMKLPIFGWGFHILEFIAVERKWEIDEQILQQKLSTLK 173
Cdd:pfam01553  10 LPRGGPAIVVANHQSYLDVLLLS-LALYKRG-RPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEYLVELL 87
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 571539519  174 DPQDPLWlaLFPEGTD----YTDQKSKNSQKFAAEAGLPVLT 211
Cdd:pfam01553  88 REGKLVV--IFPEGTRsregELLPFKKGAFRLAIEAGVPIVP 127
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
86-210 2.16e-12

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 64.98  E-value: 2.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  86 KVVFSG-DGVPMKERVLLIANHRTEVDWMYLWDLALRKgrlgcIKYILKSSLMKLPIFGWGFHILEFIAVER-KWEIDEQ 163
Cdd:cd07989   11 RVRVEGlENLPPKGPVIIVANHQSYLDPLVLGAALPRP-----IRFVAKKELFKIPFLGWLLRLLGAIPIDRgNGRSARE 85
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 571539519 164 ILQQKLSTLKDPQdplWLALFPEGTDYTDQKsknSQKF-------AAEAGLPVL 210
Cdd:cd07989   86 ALREAIEALKEGE---SVVIFPEGTRSRDGE---LLPFksgafrlAKEAGVPIV 133
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
71-188 2.51e-08

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 53.57  E-value: 2.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  71 WLSLWPSLFEKINKtkvvfSGDGVPMKER-VLLIANHRTEVDWMYLWDLALRKGRLGCIKYILKSSLMKLPIFGWGFhil 149
Cdd:cd06551    3 YLLLNFFGFVRLEV-----KGPPPPPGGGpVLFVSNHSSWWDGLILFLLLERGLRRDVYGLMDEELLERYPFFTRLG--- 74
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 571539519 150 eFIAVERKWEI-DEQILQQKLSTLKDPQDPLWlaLFPEGT 188
Cdd:cd06551   75 -AFSVDRDSPRsAAKSLKYVARLLSKPGSVVW--IFPEGT 111
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
54-215 3.10e-07

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 50.50  E-value: 3.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  54 LFSIRCSRKTVSFIFGLWLSLWPSLFEKINktkVVFSGDGVPMKERVLLIANHRTEVDWMYLWDLalrkGRlgCIKYILK 133
Cdd:PLN02901   9 LLFDRYRRKAQHFINKVWATLSTSPFYKIE---VEGLENLPSPDEPAVYVSNHQSFLDIYTLFHL----GR--PFKFISK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 134 SSLMKLPIFGWGFHILEFIAVERkweIDEqilQQKLSTLKDPQDPLW----LALFPEGTDYTDQK----SKNSQKFAAEA 205
Cdd:PLN02901  80 TSIFLIPIIGWAMYMTGHIPLKR---MDR---RSQLECLKRCMELLKkgasVFFFPEGTRSKDGKlaafKKGAFSVAAKT 153
                        170
                 ....*....|
gi 571539519 206 GLPVLTNVLL 215
Cdd:PLN02901 154 GVPVVPITLV 163
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
100-210 3.10e-03

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 37.97  E-value: 3.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519 100 VLLIANHRTEVDWMY----LWDLALRkgrlgcIKYILKSSLMKLPiFGWGFHILEFIAVER--KWEIDEQILQQKLStlk 173
Cdd:cd07988   23 VVIGAPHTSNWDFVLgllaAFALGLK------ISFLGKHSLFKPP-LGPFMRWLGGIPVDRsrAGGLVEQVVEEFRR--- 92
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 571539519 174 dpQDPLWLALFPEGT-DYTDQ-KSknsqKF---AAEAGLPVL 210
Cdd:cd07988   93 --REEFVLAIAPEGTrSKVDKwKT----GFyhiARGAGVPIL 128
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
70-192 5.41e-03

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 37.63  E-value: 5.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571539519  70 LWLSLWpSLFEKInktkVVFSGDGVPMKERVLLIANHRTE-VDWMYLWDLALRKGRlgcikYILKSSLMKLPIFGWGFHI 148
Cdd:cd07992    5 SRVILR-IYFRRI----TVVGRENVPKDGPVIFLGNHPNAlIDPLLLAATLRRPVR-----FLAKADLFKNPLIGWLLES 74
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 571539519 149 LEFIAVERK--------WEIDEQILQQKLS-TLKDPQdplWLALFPEGTDYTD 192
Cdd:cd07992   75 FGAIPVYRPkdlarggiGKISNAAVFDAVGeALKAGG---AIGIFPEGGSHDR 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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