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Conserved domains on  [gi|571488326|ref|XP_006590902|]
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probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 5 isoform X1 [Glycine max]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02510 super family cl31891
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
12-371 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


The actual alignment was detected with superfamily member PLN02510:

Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 640.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  12 GAKYQALAPWRILRGLVCLLVLLSTAFIMLVFFGFISAVIMRLFSVIYSRRATSFFFGAWLALWPFLFEKINKTKVVFSG 91
Cdd:PLN02510   6 GPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTKVVFSG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  92 DIVPSRERILLIANHRTEVDWMYLWDLALRKGCLGYIKYILKSSLMRLPVFGWAFHILEFIPVERKWEADESIMRYMLST 171
Cdd:PLN02510  86 DKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIRQMLSS 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 172 FKDPQDPLWLALFPEGTDFTEQKCLRSKKYAAEHGLPVLKNVLLPKTKGFCACLQELRSSLAAVYDVTIGYKYRCPSFLD 251
Cdd:PLN02510 166 FKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRCPSFLD 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 252 NVFGVDPSEVHIHICRFPLDSIPVSEEEMSMWLINRFQTKDQLLSNFQTQGQFPDQAAERDLSAVKSILNCMTIVTVTGT 331
Cdd:PLN02510 246 NVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVIALTTV 325
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 571488326 332 TMYYC-FSSFWFKLYVSLVCAYLVPATYFNTRPQPILSFLK 371
Cdd:PLN02510 326 FTYLTlFSSVWFKIYVSLSCAYLTSATHFNWRPPPLIESLE 366
 
Name Accession Description Interval E-value
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
12-371 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 640.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  12 GAKYQALAPWRILRGLVCLLVLLSTAFIMLVFFGFISAVIMRLFSVIYSRRATSFFFGAWLALWPFLFEKINKTKVVFSG 91
Cdd:PLN02510   6 GPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTKVVFSG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  92 DIVPSRERILLIANHRTEVDWMYLWDLALRKGCLGYIKYILKSSLMRLPVFGWAFHILEFIPVERKWEADESIMRYMLST 171
Cdd:PLN02510  86 DKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIRQMLSS 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 172 FKDPQDPLWLALFPEGTDFTEQKCLRSKKYAAEHGLPVLKNVLLPKTKGFCACLQELRSSLAAVYDVTIGYKYRCPSFLD 251
Cdd:PLN02510 166 FKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRCPSFLD 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 252 NVFGVDPSEVHIHICRFPLDSIPVSEEEMSMWLINRFQTKDQLLSNFQTQGQFPDQAAERDLSAVKSILNCMTIVTVTGT 331
Cdd:PLN02510 246 NVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVIALTTV 325
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 571488326 332 TMYYC-FSSFWFKLYVSLVCAYLVPATYFNTRPQPILSFLK 371
Cdd:PLN02510 326 FTYLTlFSSVWFKIYVSLSCAYLTSATHFNWRPPPLIESLE 366
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
76-265 4.03e-82

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 248.69  E-value: 4.03e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  76 PFLFEKINKTKVVFSGDIVPSR-ERILLIANHRTEVDWMYLWDLALRKGCLGYIKYILKSSLMRLPVFGWAFHILEFIPV 154
Cdd:cd07990    1 VFLFEWLSGVKVVVYGDEPKLPkERALIISNHRSEVDWLVLWMLADRFGRLGRLKIVLKDSLKYPPLGGWGWQLGEFIFL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 155 ERKWEADESIMRYMLSTFKDPQDPLWLALFPEGTDFTEQKCLRSKKYAAEHGLPVLKNVLLPKTKGFCACLQELRSSLAA 234
Cdd:cd07990   81 KRKWEKDEKTIKRQLKRLKDSPEPFWLLIFPEGTRFTEEKKERSQEFAEKNGLPPLKHVLLPRTKGFVAILETLRDAVDA 160
                        170       180       190
                 ....*....|....*....|....*....|..
gi 571488326 235 VYDVTIGYKYRCPSFL-DNVFGVDPSEVHIHI 265
Cdd:cd07990  161 VYDVTIAYPDGKPPSEqRLLLGGKPREVHVHV 192
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
100-210 5.30e-25

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 98.20  E-value: 5.30e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326   100 ILLIANHRTEVDWMYLWDLALRKGclGYIKYILKSSLMRLPVFGWAFHILEFIPVERKWEA-DESIMRYMLSTFKDPQdp 178
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKL--GRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRkARAALREAVELLKEGE-- 76
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 571488326   179 lWLALFPEGTDFTEQKCLRSKKYAA----EHGLPVL 210
Cdd:smart00563  77 -WLLIFPEGTRSRPGKLLPFKKGAArlalEAGVPIV 111
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
58-210 1.05e-16

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 78.13  E-value: 1.05e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  58 IYSRRATSFFFGAWLalWPFLfeKINKTKVVFSG-DIVPSRERILLIANHRTEVDWMYLWdLALRKgclgYIKYILKSSL 136
Cdd:COG0204    6 LLLRRFRYRLVRLWA--RLLL--RLLGVRVRVEGlENLPADGPVLIVANHQSWLDILLLL-AALPR----PVRFVAKKEL 76
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 571488326 137 MRLPVFGWAFHILEFIPVER-KWEADESIMRYMLSTFKDPQdplWLALFPEGTDFTEQKCLRSKK----YAAEHGLPVL 210
Cdd:COG0204   77 FKIPLLGWLLRALGAIPVDRsKRRAALRALRQAVEALKAGE---SLVIFPEGTRSPDGRLLPFKTgaarLALEAGVPIV 152
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
86-210 1.01e-14

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 70.39  E-value: 1.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326   86 KVVFSG-DIVPSRERILLIANHRTEVDWMYLWDLALRKGCLGYIkyILKSSLMRLPVFGWAFHILEFIPVERKWEAD-ES 163
Cdd:pfam01553   1 RIEVHGlENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRPLVF--VAKKELFDIPLVGWLMRLLGCIFIDRKNRKDaAG 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 571488326  164 IMRYMLSTFKDpQDPLWlaLFPEGTDFTEQKCLRSKK----YAAEHGLPVL 210
Cdd:pfam01553  79 TLEYLVELLRE-GKLVV--IFPEGTRSREGELLPFKKgafrLAIEAGVPIV 126
 
Name Accession Description Interval E-value
PLN02510 PLN02510
probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
12-371 0e+00

probable 1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178126 [Multi-domain]  Cd Length: 374  Bit Score: 640.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  12 GAKYQALAPWRILRGLVCLLVLLSTAFIMLVFFGFISAVIMRLFSVIYSRRATSFFFGAWLALWPFLFEKINKTKVVFSG 91
Cdd:PLN02510   6 GPKHRPLTPLRRLRGLICLLVLLSTAFMMLVYLAPVSAVLLRLFSVHYSRKATSFFFGSWLALWPFLFEKINKTKVVFSG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  92 DIVPSRERILLIANHRTEVDWMYLWDLALRKGCLGYIKYILKSSLMRLPVFGWAFHILEFIPVERKWEADESIMRYMLST 171
Cdd:PLN02510  86 DKVPPEERVLLIANHRTEVDWMYLWDLALRKGCLGYIKYVLKSSLMKLPVFGWAFHIFEFIPVERKWEVDEPNIRQMLSS 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 172 FKDPQDPLWLALFPEGTDFTEQKCLRSKKYAAEHGLPVLKNVLLPKTKGFCACLQELRSSLAAVYDVTIGYKYRCPSFLD 251
Cdd:PLN02510 166 FKDPRDPLWLALFPEGTDYTEAKCQRSQKFAAEHGLPILNNVLLPKTKGFVSCLQELRCSLDAVYDVTIGYKHRCPSFLD 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 252 NVFGVDPSEVHIHICRFPLDSIPVSEEEMSMWLINRFQTKDQLLSNFQTQGQFPDQAAERDLSAVKSILNCMTIVTVTGT 331
Cdd:PLN02510 246 NVFGIDPSEVHIHIRRIPLKQIPTSEDEVSAWLMDRFQLKDQLLSDFYAQGHFPNEGTEGELSTLKCLANFLAVIALTTV 325
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 571488326 332 TMYYC-FSSFWFKLYVSLVCAYLVPATYFNTRPQPILSFLK 371
Cdd:PLN02510 326 FTYLTlFSSVWFKIYVSLSCAYLTSATHFNWRPPPLIESLE 366
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
76-265 4.03e-82

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 248.69  E-value: 4.03e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  76 PFLFEKINKTKVVFSGDIVPSR-ERILLIANHRTEVDWMYLWDLALRKGCLGYIKYILKSSLMRLPVFGWAFHILEFIPV 154
Cdd:cd07990    1 VFLFEWLSGVKVVVYGDEPKLPkERALIISNHRSEVDWLVLWMLADRFGRLGRLKIVLKDSLKYPPLGGWGWQLGEFIFL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 155 ERKWEADESIMRYMLSTFKDPQDPLWLALFPEGTDFTEQKCLRSKKYAAEHGLPVLKNVLLPKTKGFCACLQELRSSLAA 234
Cdd:cd07990   81 KRKWEKDEKTIKRQLKRLKDSPEPFWLLIFPEGTRFTEEKKERSQEFAEKNGLPPLKHVLLPRTKGFVAILETLRDAVDA 160
                        170       180       190
                 ....*....|....*....|....*....|..
gi 571488326 235 VYDVTIGYKYRCPSFL-DNVFGVDPSEVHIHI 265
Cdd:cd07990  161 VYDVTIAYPDGKPPSEqRLLLGGKPREVHVHV 192
PLN02380 PLN02380
1-acyl-sn-glycerol-3-phosphate acyltransferase
30-307 4.54e-60

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 178006 [Multi-domain]  Cd Length: 376  Bit Score: 198.43  E-value: 4.54e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  30 LLVLLSTAFIMLvfFGFISAVIMRLFSVIYSRRATSFFFGA-WLALwPFLFEKINKTKVVFSGDIVPSR----ERILLIA 104
Cdd:PLN02380  14 LLFLLSGLIVNL--IQAVCFILVRPLSKSLYRRINRAVAELlWLEL-IWLVDWWAGVKVQLYADEETFElmgkEHALVIS 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 105 NHRTEVDWMYLWDLALRKGCLGYIKYILKSSLMRLPVFGWAFHILEFIPVERKWEADESIMRYMLSTFKDPQDPLWLALF 184
Cdd:PLN02380  91 NHRSDIDWLVGWILAQRSGCLGSALAVMKKSSKFLPVIGWSMWFSEYVFLERSWAKDENTLKSGFQRLKDFPRPFWLALF 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 185 PEGTDFTEQKCLRSKKYAAEHGLPVLKNVLLPKTKGFCACLQELRSSLAAVYDVT--IGYKYRCPSFLdNVFGVDPSEVH 262
Cdd:PLN02380 171 VEGTRFTQAKLLAAQEYAASRGLPVPRNVLIPRTKGFVSAVSNMRSFVPAIYDVTvaVPKGQPAPTML-RIFRGQSSVVH 249
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 571488326 263 IHICRFPLDSIPVSEEEMSMWLINRFQTKDQLLSNFQTQGQFPDQ 307
Cdd:PLN02380 250 VHIKRHSMKELPETDDGIAQWCKDVFVAKDALLDKHFAEDTFGDQ 294
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
100-210 5.30e-25

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 98.20  E-value: 5.30e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326   100 ILLIANHRTEVDWMYLWDLALRKGclGYIKYILKSSLMRLPVFGWAFHILEFIPVERKWEA-DESIMRYMLSTFKDPQdp 178
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKL--GRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRkARAALREAVELLKEGE-- 76
                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 571488326   179 lWLALFPEGTDFTEQKCLRSKKYAA----EHGLPVL 210
Cdd:smart00563  77 -WLLIFPEGTRSRPGKLLPFKKGAArlalEAGVPIV 111
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
58-210 1.05e-16

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 78.13  E-value: 1.05e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  58 IYSRRATSFFFGAWLalWPFLfeKINKTKVVFSG-DIVPSRERILLIANHRTEVDWMYLWdLALRKgclgYIKYILKSSL 136
Cdd:COG0204    6 LLLRRFRYRLVRLWA--RLLL--RLLGVRVRVEGlENLPADGPVLIVANHQSWLDILLLL-AALPR----PVRFVAKKEL 76
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 571488326 137 MRLPVFGWAFHILEFIPVER-KWEADESIMRYMLSTFKDPQdplWLALFPEGTDFTEQKCLRSKK----YAAEHGLPVL 210
Cdd:COG0204   77 FKIPLLGWLLRALGAIPVDRsKRRAALRALRQAVEALKAGE---SLVIFPEGTRSPDGRLLPFKTgaarLALEAGVPIV 152
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
86-210 1.01e-14

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 70.39  E-value: 1.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326   86 KVVFSG-DIVPSRERILLIANHRTEVDWMYLWDLALRKGCLGYIkyILKSSLMRLPVFGWAFHILEFIPVERKWEAD-ES 163
Cdd:pfam01553   1 RIEVHGlENLPRGGPAIVVANHQSYLDVLLLSLALYKRGRPLVF--VAKKELFDIPLVGWLMRLLGCIFIDRKNRKDaAG 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 571488326  164 IMRYMLSTFKDpQDPLWlaLFPEGTDFTEQKCLRSKK----YAAEHGLPVL 210
Cdd:pfam01553  79 TLEYLVELLRE-GKLVV--IFPEGTRSREGELLPFKKgafrLAIEAGVPIV 126
Acyltransf_C pfam16076
Acyltransferase C-terminus; This domain is found at the C-terminus of several different ...
258-307 3.54e-14

Acyltransferase C-terminus; This domain is found at the C-terminus of several different acyltransferases including 1-acyl-sn-glycerol-3-phosphate acyltransferase, acyl-CoA:lysophosphatidylglycerol acyltransferase 1 and lysocardiolipin acyltransferase 1.


Pssm-ID: 465006 [Multi-domain]  Cd Length: 74  Bit Score: 66.83  E-value: 3.54e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 571488326  258 PSEVHIHICRFPLDSIPVSEEEMSMWLINRFQTKDQLLSNFQTQGQFPDQ 307
Cdd:pfam16076   7 PSEVHMYIRRIPLEELPEDEEELAQWLHDLFVEKDKLLDYFYETGTFFPG 56
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
86-210 1.78e-13

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 68.07  E-value: 1.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  86 KVVFSG-DIVPSRERILLIANHRTEVDWMYLWDLALRKgclgyIKYILKSSLMRLPVFGWAFHILEFIPVER-KWEADES 163
Cdd:cd07989   11 RVRVEGlENLPPKGPVIIVANHQSYLDPLVLGAALPRP-----IRFVAKKELFKIPFLGWLLRLLGAIPIDRgNGRSARE 85
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 571488326 164 IMRYMLSTFKDPQdplWLALFPEGTdfteqkclRSK------------KYAAEHGLPVL 210
Cdd:cd07989   86 ALREAIEALKEGE---SVVIFPEGT--------RSRdgellpfksgafRLAKEAGVPIV 133
PRK14014 PRK14014
putative acyltransferase; Provisional
24-303 1.03e-12

putative acyltransferase; Provisional


Pssm-ID: 237584 [Multi-domain]  Cd Length: 301  Bit Score: 67.95  E-value: 1.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  24 LRG-LVCLLVLLSTAF--IMLVFFGFI-----SAVIMRLFSviysrRATSFFFGAWLALWPFLFEKINKTKVVFSGDIVP 95
Cdd:PRK14014   9 LRGlLSILLLILNTLFwsVPIIILGLLklllpIPAIRRACS-----RLLNFIAEAWISINNVILRLLPRTQWDVEGLEGL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  96 SR-ERILLIANHRTEVDWMYLWDLALRKgcLGYIKYILKSSLMRLPVFGWAFHILEFiPV-------------ERKWEaD 161
Cdd:PRK14014  84 SKkGWYLVISNHQSWVDILVLQYVFNRR--IPMLKFFLKQELIWVPFLGLAWWALDF-PFmkryskaylaknpELKGK-D 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 162 ESIMRYMLSTFKDpqDPLWLALFPEGTDFTEQKCLRSKK-YaaehglpvlKNVLLPKTKGFCACLQELRSSLAAVYDVTI 240
Cdd:PRK14014 160 LETTRRACEKFKR--MPTTIVNFVEGTRFTPEKHQQQQSpY---------QHLLKPKAGGIAFALNAMGEQFDGLLDVTI 228
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 571488326 241 GYKYRCPSFLDNVFGvDPSEVHIHICRFPLDSIPVSE--------EEMSMWLINRFQTKDQLLSNFQTQGQ 303
Cdd:PRK14014 229 VYPDGRPSFWDLLSG-RVKKIVVHVRLLPIPEELIGDyfndkefrRRFQQWLNQLWQEKDQLIEQLLAQYN 298
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
71-200 1.34e-10

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 60.12  E-value: 1.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  71 WLALWPFLFEKINKTKVvfsgDIVPSRERILLIANHRTEVDWMYLWdLALRKGCLGYIKYILK-SSLMRLPVFGWAFhil 149
Cdd:cd06551    3 YLLLNFFGFVRLEVKGP----PPPPGGGPVLFVSNHSSWWDGLILF-LLLERGLRRDVYGLMDeELLERYPFFTRLG--- 74
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 571488326 150 eFIPVERKW-EADESIMRYMLSTFKDPQDPLWlaLFPEGTDFTEQKCLRSKK 200
Cdd:cd06551   75 -AFSVDRDSpRSAAKSLKYVARLLSKPGSVVW--IFPEGTRTRRDKRPLQFK 123
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
40-215 7.81e-06

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 46.26  E-value: 7.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  40 MLVFFGFIsavimrLFSVIYSRRATSFFFGAWLALWPFLFEKINktkVVFSGDIVPSRERILLIANHRTEVDWMYLwdLA 119
Cdd:PLN02901   1 MLVQHPFV------LLFDRYRRKAQHFINKVWATLSTSPFYKIE---VEGLENLPSPDEPAVYVSNHQSFLDIYTL--FH 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 120 LRKGclgyIKYILKSSLMRLPVFGWAFHILEFIPVERkweADEsimRYMLSTFKDPQDPLW----LALFPEGTDFTEQKC 195
Cdd:PLN02901  70 LGRP----FKFISKTSIFLIPIIGWAMYMTGHIPLKR---MDR---RSQLECLKRCMELLKkgasVFFFPEGTRSKDGKL 139
                        170       180
                 ....*....|....*....|....
gi 571488326 196 LRSKK----YAAEHGLPVLKNVLL 215
Cdd:PLN02901 140 AAFKKgafsVAAKTGVPVVPITLV 163
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
70-188 9.00e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 46.10  E-value: 9.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  70 AWLALWPFlFEKInktkVVFSGDIVPSRERILLIANHRTEvdwmyLWD-LALRKGCLGYIKYILKSSLMRLPVFGWAFHI 148
Cdd:cd07992    5 SRVILRIY-FRRI----TVVGRENVPKDGPVIFLGNHPNA-----LIDpLLLAATLRRPVRFLAKADLFKNPLIGWLLES 74
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 571488326 149 LEFIPVER-KWEADESIMRYMLS-TFKDPQDPL----WLALFPEGT 188
Cdd:cd07992   75 FGAIPVYRpKDLARGGIGKISNAaVFDAVGEALkaggAIGIFPEGG 120
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
72-209 7.71e-05

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 43.36  E-value: 7.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326  72 LALWPFLFEKINktkvvFSGDIVPSRERILLIANHRTEVDWMYLwdlalrkGCLGYIKYILKSSLMRLPVFGWAFHILEF 151
Cdd:cd07991    3 VLLFAFGFYVIK-----VHGKPDPPEAPRIIVANHTSFIDPLIL-------FSDLFPSIVAKKELGKLPFIGTILRALGC 70
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 571488326 152 IPVERKWEAD-----ESIMRYMLSTFKDPqdplwLALFPEGTdFTEQKCL-RSKKYAAEHGLPV 209
Cdd:cd07991   71 IFVDRSEPKDrkkvvEEIKERATDPNWPP-----ILIFPEGT-TTNGKALiMFKKGAFEPGVPV 128
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
100-188 9.44e-05

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 42.59  E-value: 9.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 571488326 100 ILLIANHRTEVDWMY----LWDLALRkgclgyIKYILKSSLMRLPvFGWAFHILEFIPVERkwEADESIMRYMLSTFKDp 175
Cdd:cd07988   23 VVIGAPHTSNWDFVLgllaAFALGLK------ISFLGKHSLFKPP-LGPFMRWLGGIPVDR--SRAGGLVEQVVEEFRR- 92
                         90
                 ....*....|...
gi 571488326 176 QDPLWLALFPEGT 188
Cdd:cd07988   93 REEFVLAIAPEGT 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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