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Conserved domains on  [gi|514821292|ref|XP_004985327|]
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homeobox-leucine zipper protein HOX12 [Setaria italica]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10441114)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

CATH:  1.10.10.60
Gene Ontology:  GO:0003677
PubMed:  21557080|26464018|27768937|1357790
SCOP:  4000291

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
58-111 7.69e-16

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 69.45  E-value: 7.69e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 514821292   58 KKRR--LSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHK 111
Cdd:pfam00046   1 RRKRttFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
58-111 7.69e-16

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 69.45  E-value: 7.69e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 514821292   58 KKRR--LSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHK 111
Cdd:pfam00046   1 RRKRttFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 58-111 5.61e-15

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 66.89  E-value: 5.61e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 514821292    58 KKRRLSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHK 111
Cdd:smart00389   4 KRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 58-113 7.37e-14

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 64.19  E-value: 7.37e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 514821292  58 KKRRLSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHKSK 113
Cdd:cd00086    3 KRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
58-113 7.14e-07

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 47.43  E-value: 7.14e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 514821292  58 KKRRLSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHKSK 113
Cdd:COG5576   54 KRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKK 109
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
58-111 7.69e-16

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 69.45  E-value: 7.69e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 514821292   58 KKRR--LSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHK 111
Cdd:pfam00046   1 RRKRttFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 58-111 5.61e-15

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 66.89  E-value: 5.61e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 514821292    58 KKRRLSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHK 111
Cdd:smart00389   4 KRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 58-113 7.37e-14

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 64.19  E-value: 7.37e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 514821292  58 KKRRLSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHKSK 113
Cdd:cd00086    3 KRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
58-113 7.14e-07

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 47.43  E-value: 7.14e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 514821292  58 KKRRLSDEQARQLEINFRKERKLETPRKVQLAAELGLDAKQVAVWFQNRRARHKSK 113
Cdd:COG5576   54 KRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKK 109
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 85-109 3.97e-03

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


Pssm-ID: 428673  Cd Length: 39  Bit Score: 34.03  E-value: 3.97e-03
                          10        20
                  ....*....|....*....|....*
gi 514821292   85 KVQLAAELGLDAKQVAVWFQNRRAR 109
Cdd:pfam05920  15 KAELAKETGLSRKQISNWFINARRR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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