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Conserved domains on  [gi|470104949|ref|XP_004288854|]
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PREDICTED: transcription factor MYB114-like [Fragaria vesca subsp. vesca]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 999994)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03091 super family cl33633
hypothetical protein; Provisional
 7-123 1.63e-47

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PLN03091:

Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 158.22  E-value: 1.63e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470104949   7 LRKGAWTREEDNILRQCVAKHGEGKWHQIPAAAGLKRCRKSCRLRWLNYLKPDIKRGDFEDAEVDLIIRLHKLLGNRWSL 86
Cdd:PLN03091  12 LRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQ 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 470104949  87 IAGRLPGRTTNDVKNFWN------MKQRQENP---RRLS---NREQKSQ 123
Cdd:PLN03091  92 IAAQLPGRTDNEIKNLWNsclkkkLRQRGIDPnthKPLSeveNGEDKNP 140
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 7-123 1.63e-47

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 158.22  E-value: 1.63e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470104949   7 LRKGAWTREEDNILRQCVAKHGEGKWHQIPAAAGLKRCRKSCRLRWLNYLKPDIKRGDFEDAEVDLIIRLHKLLGNRWSL 86
Cdd:PLN03091  12 LRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQ 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 470104949  87 IAGRLPGRTTNDVKNFWN------MKQRQENP---RRLS---NREQKSQ 123
Cdd:PLN03091  92 IAAQLPGRTDNEIKNLWNsclkkkLRQRGIDPnthKPLSeveNGEDKNP 140
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 4-104 9.91e-17

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 74.82  E-value: 9.91e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470104949   4 QTGLRKGAWTREEDNILRQCVAKHGEGKWHQIpAAAGLKRCRKSCRLRWLNYLKPDIKRGDFEDAEVDLIIRLHKLLGNR 83
Cdd:COG5147   15 QTKRKGGSWKRTEDEDLKALVKKLGPNNWSKV-ASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ 93

                         90       100
                 ....*....|....*....|.
gi 470104949  84 WSLIAGRLPGRTTNDVKNFWN 104
Cdd:COG5147   94 WSTIADYKDRRTAQQCVERYV 114
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 9-56 3.28e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 54.05  E-value: 3.28e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 470104949    9 KGAWTREEDNILRQCVAKHGeGKWHQIPAAAGlKRCRKSCRLRWLNYL 56
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLP-GRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
9-58 6.49e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 53.38  E-value: 6.49e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 470104949     9 KGAWTREEDNILRQCVAKHGEGKWHQIPAAAGlKRCRKSCRLRWLNYLKP 58
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 11-56 3.90e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 51.42  E-value: 3.90e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 470104949  11 AWTREEDNILRQCVAKHGEGKWHQIPAAAGlKRCRKSCRLRWLNYL 56
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 7-123 1.63e-47

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 158.22  E-value: 1.63e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470104949   7 LRKGAWTREEDNILRQCVAKHGEGKWHQIPAAAGLKRCRKSCRLRWLNYLKPDIKRGDFEDAEVDLIIRLHKLLGNRWSL 86
Cdd:PLN03091  12 LRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQ 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 470104949  87 IAGRLPGRTTNDVKNFWN------MKQRQENP---RRLS---NREQKSQ 123
Cdd:PLN03091  92 IAAQLPGRTDNEIKNLWNsclkkkLRQRGIDPnthKPLSeveNGEDKNP 140
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 4-114 3.50e-46

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 149.46  E-value: 3.50e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470104949   4 QTGLRKGAWTREEDNILRQCVAKHGEGKWHQIPAAAGLKRCRKSCRLRWLNYLKPDIKRGDFEDAEVDLIIRLHKLLGNR 83
Cdd:PLN03212  20 KMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNR 99

                         90       100       110
                 ....*....|....*....|....*....|.
gi 470104949  84 WSLIAGRLPGRTTNDVKNFWNMKQRQENPRR 114
Cdd:PLN03212 100 WSLIAGRIPGRTDNEIKNYWNTHLRKKLLRQ 130
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 4-104 9.91e-17

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 74.82  E-value: 9.91e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470104949   4 QTGLRKGAWTREEDNILRQCVAKHGEGKWHQIpAAAGLKRCRKSCRLRWLNYLKPDIKRGDFEDAEVDLIIRLHKLLGNR 83
Cdd:COG5147   15 QTKRKGGSWKRTEDEDLKALVKKLGPNNWSKV-ASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ 93

                         90       100
                 ....*....|....*....|.
gi 470104949  84 WSLIAGRLPGRTTNDVKNFWN 104
Cdd:COG5147   94 WSTIADYKDRRTAQQCVERYV 114
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 9-56 3.28e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 54.05  E-value: 3.28e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 470104949    9 KGAWTREEDNILRQCVAKHGeGKWHQIPAAAGlKRCRKSCRLRWLNYL 56
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLP-GRTDNQCKNRWQNYL 46
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 62-105 5.34e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 53.66  E-value: 5.34e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 470104949   62 RGDFEDAEVDLIIRLHKLLGNRWSLIAGRLPGRTTNDVKNFWNM 105
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
9-58 6.49e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 53.38  E-value: 6.49e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 470104949     9 KGAWTREEDNILRQCVAKHGEGKWHQIPAAAGlKRCRKSCRLRWLNYLKP 58
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 11-56 3.90e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 51.42  E-value: 3.90e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 470104949  11 AWTREEDNILRQCVAKHGEGKWHQIPAAAGlKRCRKSCRLRWLNYL 56
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 12-70 7.86e-10

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 51.16  E-value: 7.86e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 470104949   12 WTREEDNILRQCVAKHGeGKWHQIPAAAGlKRCRKSCRLRWLNYLKPDIKRGDFEDAEV 70
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPKISRGPWSKEED 57
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 69-105 1.48e-06

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 42.18  E-value: 1.48e-06
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 470104949  69 EVDLIIRLHKLLG-NRWSLIAGRLPGRTTNDVKNFWNM 105
Cdd:cd00167    6 EDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRN 43
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
62-105 3.17e-06

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 41.44  E-value: 3.17e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 470104949    62 RGDFEDAEVDLIIRLHKLLG-NRWSLIAGRLPGRTTNDVKNFWNM 105
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRN 45
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 12-35 7.80e-04

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 35.24  E-value: 7.80e-04
                         10        20
                 ....*....|....*....|....
gi 470104949  12 WTREEDNILRQCVAKHGEGKWHQI 35
Cdd:cd11660    3 WTDEEDEALVEGVEKYGVGNWAKI 26
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 65-104 2.66e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 33.82  E-value: 2.66e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 470104949   65 FEDAEVDLIIRLHKLLGNRWSLIAGRLPGRTTNDVKNFWN 104
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWR 40
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 9-109 3.45e-03

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 35.92  E-value: 3.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 470104949   9 KGAWTREEDNILRQCVAKHGEgkwHQIPAAAGLKRCRKSCRLRWLNYLKPDIKRGDfedaevdliirlhkllgNRWSLIA 88
Cdd:COG5147  291 RGKWTKEEEQELAKLVVEHGG---SWTEIGKLLGRMPNDCRDRWRDYVKCGDTLKR-----------------NRWSIEE 350

                         90       100
                 ....*....|....*....|.
gi 470104949  89 GRLPGRTTNDVKNFWNMKQRQ 109
Cdd:COG5147  351 EELLDKVVNEMRLEAQQSSRI 371
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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