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Conserved domains on  [gi|357521121|ref|XP_003630849|]
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zinc finger protein CONSTANS-LIKE 16 [Medicago truncatula]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CCT pfam06203
CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino ...
358-400 8.77e-22

CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino acids and has been called a CCT motif after Co, Col and Toc1. The CCT motif is about 45 amino acids long and contains a putative nuclear localization signal within the second half of the CCT motif. Toc1 mutants have been identified in this region.


:

Pssm-ID: 461849  Cd Length: 44  Bit Score: 87.55  E-value: 8.77e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 357521121  358 REARVSRYREKRRTRLFAKKIRYEVRKLNAEKRPRMKGRFVKR 400
Cdd:pfam06203   1 REEALLRYREKRKTRKFDKKIRYESRKALADKRPRVKGRFVKA 43
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
21-64 3.02e-17

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


:

Pssm-ID: 380879  Cd Length: 44  Bit Score: 75.03  E-value: 3.02e-17
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 357521121  21 ACDSCLRRRARWFCAADDAFLCHGCDNLVHSANLLASRHERVRL 64
Cdd:cd19821    1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQRVPL 44
 
Name Accession Description Interval E-value
CCT pfam06203
CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino ...
358-400 8.77e-22

CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino acids and has been called a CCT motif after Co, Col and Toc1. The CCT motif is about 45 amino acids long and contains a putative nuclear localization signal within the second half of the CCT motif. Toc1 mutants have been identified in this region.


Pssm-ID: 461849  Cd Length: 44  Bit Score: 87.55  E-value: 8.77e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 357521121  358 REARVSRYREKRRTRLFAKKIRYEVRKLNAEKRPRMKGRFVKR 400
Cdd:pfam06203   1 REEALLRYREKRKTRKFDKKIRYESRKALADKRPRVKGRFVKA 43
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
21-64 3.02e-17

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


Pssm-ID: 380879  Cd Length: 44  Bit Score: 75.03  E-value: 3.02e-17
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 357521121  21 ACDSCLRRRARWFCAADDAFLCHGCDNLVHSANLLASRHERVRL 64
Cdd:cd19821    1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQRVPL 44
BBOX smart00336
B-Box-type zinc finger;
19-64 5.40e-06

B-Box-type zinc finger;


Pssm-ID: 197662 [Multi-domain]  Cd Length: 42  Bit Score: 43.09  E-value: 5.40e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 357521121    19 ARACDSCLRRRARWFCAADDAFLCHGCDNLVHsanllaSRHERVRL 64
Cdd:smart00336   3 APKCDSHGDEPAEFFCEECGALLCRTCDEAEH------RGHTVVLL 42
zf-B_box pfam00643
B-box zinc finger;
22-64 6.44e-04

B-box zinc finger;


Pssm-ID: 459886 [Multi-domain]  Cd Length: 42  Bit Score: 37.07  E-value: 6.44e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 357521121   22 CDSCLRRRARWFCAADDAFLCHGCDNLVHsanllaSRHERVRL 64
Cdd:pfam00643   6 CPEHEEEPLTLYCNDCQELLCEECSVGEH------RGHTVVPL 42
 
Name Accession Description Interval E-value
CCT pfam06203
CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino ...
358-400 8.77e-22

CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino acids and has been called a CCT motif after Co, Col and Toc1. The CCT motif is about 45 amino acids long and contains a putative nuclear localization signal within the second half of the CCT motif. Toc1 mutants have been identified in this region.


Pssm-ID: 461849  Cd Length: 44  Bit Score: 87.55  E-value: 8.77e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 357521121  358 REARVSRYREKRRTRLFAKKIRYEVRKLNAEKRPRMKGRFVKR 400
Cdd:pfam06203   1 REEALLRYREKRKTRKFDKKIRYESRKALADKRPRVKGRFVKA 43
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
21-64 3.02e-17

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


Pssm-ID: 380879  Cd Length: 44  Bit Score: 75.03  E-value: 3.02e-17
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 357521121  21 ACDSCLRRRARWFCAADDAFLCHGCDNLVHSANLLASRHERVRL 64
Cdd:cd19821    1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQRVPL 44
Bbox1 cd19757
B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of ...
22-64 3.68e-07

B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of around 40 amino acid residues in length. It has been found in transcription factors, ribonucleoproteins and proto-oncoproteins, such as in TRIM (tripartite motif) proteins that consist of an N-terminal RING finger (originally called an A-box), followed by 1-2 B-box domains and a coiled-coil domain (also called RBCC for Ring, B-box, Coiled-Coil). The B-box-type zinc finger often presents in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain, in functionally unrelated proteins, most likely mediating protein-protein interactions. Based on different consensus sequences and the spacing of the 7-8 zinc-binding residues, the B-box-type zinc fingers can be divided into two groups, type 1 (Bbox1: C6H2) and type 2 (Bbox2: CHC3H2). This family corresponds to the type 1 B-box (Bbox1).


Pssm-ID: 380815 [Multi-domain]  Cd Length: 44  Bit Score: 46.34  E-value: 3.68e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 357521121  22 CDSCLRRRARWFCAADDAFLCHGCDNLVHSANLLASRHERVRL 64
Cdd:cd19757    2 CDECEEREATVYCLECEEFLCDDCSDAIHRRGKLTRSHKLVPL 44
BBOX smart00336
B-Box-type zinc finger;
19-64 5.40e-06

B-Box-type zinc finger;


Pssm-ID: 197662 [Multi-domain]  Cd Length: 42  Bit Score: 43.09  E-value: 5.40e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 357521121    19 ARACDSCLRRRARWFCAADDAFLCHGCDNLVHsanllaSRHERVRL 64
Cdd:smart00336   3 APKCDSHGDEPAEFFCEECGALLCRTCDEAEH------RGHTVVLL 42
zf-B_box pfam00643
B-box zinc finger;
22-64 6.44e-04

B-box zinc finger;


Pssm-ID: 459886 [Multi-domain]  Cd Length: 42  Bit Score: 37.07  E-value: 6.44e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 357521121   22 CDSCLRRRARWFCAADDAFLCHGCDNLVHsanllaSRHERVRL 64
Cdd:pfam00643   6 CPEHEEEPLTLYCNDCQELLCEECSVGEH------RGHTVVPL 42
Bbox2_TRIM23_C-IX_rpt1 cd19773
first B-box-type 2 zinc finger found in tripartite motif-containing protein 23 (TRIM23) and ...
22-64 6.11e-03

first B-box-type 2 zinc finger found in tripartite motif-containing protein 23 (TRIM23) and similar proteins; TRIM23, also known as ADP-ribosylation factor domain-containing protein 1, GTP-binding protein ARD-1, or RING finger protein 46 (RNF46), is an E3 ubiquitin-protein ligase belonging to the C-IX subclass of TRIM (tripartite motif) family of proteins that are defined by an N-terminal RBCC (RING, Bbox, and coiled coil) domains, including three consecutive zinc-binding domains, a RING finger, two Bbox2, and a coiled coil region, as well as C-terminal ADP ribosylation factor (ARF) domains. The type 2 B-box (Bbox2) zinc finger is characterized by a CHC3H2 zinc-binding consensus motif. TRIM23 is involved in nuclear factor (NF)-kappaB activation. It mediates atypical lysine 27 (K27)-linked polyubiquitin conjugation to NF-kappaB essential modulator NEMO, also known as IKKgamma, which plays an important role in the NF-kappaB pathway, and this conjugation is essential for TLR3- and RIG-I/MDA5-mediated antiviral innate and inflammatory responses. It also regulates adipocyte differentiation via stabilization of the adipogenic activator peroxisome proliferator-activated receptor gamma (PPARgamma) through atypical ubiquitin conjugation to PPARgamma. Moreover, TRIM23 interacts with and polyubiquitinates yellow fever virus (YFV) NS5 to promote its binding to STAT2 and trigger type I interferon (IFN-I) signaling inhibition.


Pssm-ID: 380831  Cd Length: 50  Bit Score: 34.62  E-value: 6.11e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 357521121  22 CDSCLRRRARWFCAADDAFLCHGCDNLVHSANLLaSRHERVRL 64
Cdd:cd19773    5 CDENEDHEATLYCTVCSTNLCEECFTSTHSTKTL-SKHRRVPL 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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