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Conserved domains on  [gi|303280852|ref|XP_003059718|]
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uncharacterized protein MICPUCDRAFT_18430, partial [Micromonas pusilla CCMP1545]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-400 3.88e-116

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 342.91  E-value: 3.88e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRppevdpkRHKAPPLALE 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGER-AFCAGGDVRALYEAA-------KAGGGEAGRD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   99 FFNREYQMNHQLANARTPHVAIMDGVvmgggcgvSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLPGRVGHALA 178
Cdd:pfam16113  73 FFREEYRLNYLIATYPKPYVALMDGIvmgggvglSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  179 LTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAlertfsggettseldrnAKDWANKVDEELRKLEKETsgevKETP 258
Cdd:pfam16113 153 LTGARLNGADALAAGLATHYVPSARLPALEEALAAL-----------------DWSDPADVDAVLAEFAEES----DPPP 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  259 NDLHPHLAVIDRWFVSDDVQEVDLTLNAAAVGGrrererKVAKELLELMRAGCPASLRVTAAMLKRVRppvdimnvsggp 338
Cdd:pfam16113 212 SPLAAHREAIDRCFSADTVEEIIAALEAEADGD------EWAAETLKTLRKRSPTSLKVTLRQLRRGR------------ 273

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 303280852  339 ppPLDLARCLRMEFRAVAECISRDDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFF 400
Cdd:pfam16113 274 --KLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRN--PKWSPATLEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-400 3.88e-116

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 342.91  E-value: 3.88e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRppevdpkRHKAPPLALE 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGER-AFCAGGDVRALYEAA-------KAGGGEAGRD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   99 FFNREYQMNHQLANARTPHVAIMDGVvmgggcgvSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLPGRVGHALA 178
Cdd:pfam16113  73 FFREEYRLNYLIATYPKPYVALMDGIvmgggvglSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  179 LTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAlertfsggettseldrnAKDWANKVDEELRKLEKETsgevKETP 258
Cdd:pfam16113 153 LTGARLNGADALAAGLATHYVPSARLPALEEALAAL-----------------DWSDPADVDAVLAEFAEES----DPPP 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  259 NDLHPHLAVIDRWFVSDDVQEVDLTLNAAAVGGrrererKVAKELLELMRAGCPASLRVTAAMLKRVRppvdimnvsggp 338
Cdd:pfam16113 212 SPLAAHREAIDRCFSADTVEEIIAALEAEADGD------EWAAETLKTLRKRSPTSLKVTLRQLRRGR------------ 273

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 303280852  339 ppPLDLARCLRMEFRAVAECISRDDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFF 400
Cdd:pfam16113 274 --KLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRN--PKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 9-402 1.01e-92

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 283.25  E-value: 1.01e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRppevdpk 88
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGER-GFCAGGDIRALYEAA------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  89 RHKAPPLALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSN 168
Cdd:PRK05617  75 RAGDPLAADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 169 LPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALERTFSGGettseldrnakdwankVDEELRKLEK 248
Cdd:PRK05617 155 APGALGTYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGADV----------------VDAALAAFAT 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 249 EtsgevkETPNDLHPHLAVIDRWFVSDDVQEVDLTLNAAAVGgrrererkVAKELLELMRAGCPASLRVTAAMLKRVRpp 328
Cdd:PRK05617 219 P------APASELAAQRAWIDECFAGDTVEDIIAALEADGGE--------FAAKTADTLRSRSPTSLKVTLEQLRRAR-- 282

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 303280852 329 vdimnvsggpppPLDLARCLRMEFRAVAECISRDDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFFEP 402
Cdd:PRK05617 283 ------------GLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKDRN--PKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 11-215 7.47e-38

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 136.15  E-value: 7.47e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVYDMRPpevdpkrh 90
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG--KAFCAGADLKELAALSD-------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 kAPPLALEFFNREYQMNHQLANARTPHVAImdgvvmgggcgvsIHGA-------------FRVATERTVLAMPECVIGLV 157
Cdd:cd06558   71 -AGEEARAFIRELQELLRALLRLPKPVIAA-------------VNGAalggglelalacdIRIAAEDAKFGLPEVKLGLV 136

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 303280852 158 PDVGATYFLSNLPG-RVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:cd06558  137 PGGGGTQRLPRLVGpARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 11-215 9.03e-34

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 126.82  E-value: 9.03e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVYDMRPPEVdpkrh 90
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG--KAFCAGADLKELAAAADPEE----- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 kapplALEFFNREYQMNHQLANARTPHVAimdgvvmgggcgvSIHGA-------------FRVATERTVLAMPECVIGLV 157
Cdd:COG1024   74 -----ARAFARGLQRLFRALRRLPKPVIA-------------AVNGAalggglelalacdLRIAAEDARFGLPEVRLGLI 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 158 PDVGATYFLSNLPGRvGHA--LALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:COG1024  136 PGGGGTQRLPRLVGL-ARAkeLLLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARL 194
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 11-238 3.82e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 62.16  E-value: 3.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   11 ILVDAVSSVRVVTLNRPD-KLNVLSDSMVTRLSELWAEWDADKDVKCIVLNgAGERPCLCAGGDVKAVYDMRPPEvdpkr 89
Cdd:TIGR02441  15 RHYEVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLI-SGKPGSFVAGADIQMIAACKTAQ----- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   90 hkapplALEFFNREYQ-MNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATE--RTVLAMPECVIGLVPDVGATYFL 166
Cdd:TIGR02441  89 ------EVTQLSQEGQeMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 303280852  167 SNLPGrVGHAL--ALTGRRVGGYDAKKLGLathaigssaVGKIVESLATAL----ERTFSGGETTSEldRNAKDWANK 238
Cdd:TIGR02441 163 PKLTG-VPAALdmMLTGKKIRADRAKKMGI---------VDQLVDPLGPGLkpaeENTIEYLEEVAV--KFAQGLANG 228
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-400 3.88e-116

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 342.91  E-value: 3.88e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRppevdpkRHKAPPLALE 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGER-AFCAGGDVRALYEAA-------KAGGGEAGRD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   99 FFNREYQMNHQLANARTPHVAIMDGVvmgggcgvSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLPGRVGHALA 178
Cdd:pfam16113  73 FFREEYRLNYLIATYPKPYVALMDGIvmgggvglSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  179 LTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAlertfsggettseldrnAKDWANKVDEELRKLEKETsgevKETP 258
Cdd:pfam16113 153 LTGARLNGADALAAGLATHYVPSARLPALEEALAAL-----------------DWSDPADVDAVLAEFAEES----DPPP 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  259 NDLHPHLAVIDRWFVSDDVQEVDLTLNAAAVGGrrererKVAKELLELMRAGCPASLRVTAAMLKRVRppvdimnvsggp 338
Cdd:pfam16113 212 SPLAAHREAIDRCFSADTVEEIIAALEAEADGD------EWAAETLKTLRKRSPTSLKVTLRQLRRGR------------ 273

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 303280852  339 ppPLDLARCLRMEFRAVAECISRDDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFF 400
Cdd:pfam16113 274 --KLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRN--PKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 9-402 1.01e-92

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 283.25  E-value: 1.01e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRppevdpk 88
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGER-GFCAGGDIRALYEAA------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  89 RHKAPPLALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSN 168
Cdd:PRK05617  75 RAGDPLAADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 169 LPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALERTFSGGettseldrnakdwankVDEELRKLEK 248
Cdd:PRK05617 155 APGALGTYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGADV----------------VDAALAAFAT 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 249 EtsgevkETPNDLHPHLAVIDRWFVSDDVQEVDLTLNAAAVGgrrererkVAKELLELMRAGCPASLRVTAAMLKRVRpp 328
Cdd:PRK05617 219 P------APASELAAQRAWIDECFAGDTVEDIIAALEADGGE--------FAAKTADTLRSRSPTSLKVTLEQLRRAR-- 282

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 303280852 329 vdimnvsggpppPLDLARCLRMEFRAVAECISRDDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFFEP 402
Cdd:PRK05617 283 ------------GLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKDRN--PKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 11-408 3.52e-60

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 200.80  E-value: 3.52e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPPEVDpkrh 90
Cdd:PLN02874  13 VLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGR--AFSAGGDLKMFYDGRESDDS---- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 kapplALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLP 170
Cdd:PLN02874  87 -----CLEVVYRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLP 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 171 GRVGHALALTGRRVGGYDAKKLGLATHAIGSsavGKIVEslataLERTFsggettSELDRNAKDWANKVDEELrkleket 250
Cdd:PLN02874 162 GHLGEYLALTGARLNGKEMVACGLATHFVPS---EKLPE-----LEKRL------LNLNSGDESAVQEAIEEF------- 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 251 SGEVKETPNDLHPHLAVIDRWFVSDDVQEVDLTLNAAAvggrRERERKVAKELLELMRAGCPASLRVTAAMLKRVRPPvd 330
Cdd:PLN02874 221 SKDVQADEDSILNKQSWINECFSKDTVEEIIKAFESEA----SKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQ-- 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 331 imnvsggpppplDLARCLRMEFRAVAECISR---DDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFFEPGSREV 407
Cdd:PLN02874 295 ------------SLAECLKKEFRLTMNILRStvsDDVYEGIRALVIDKDNA--PKWNPSTLDEVTDEKVDLVFQPFKARE 360


                 .
gi 303280852 408 E 408
Cdd:PLN02874 361 E 361
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 3-408 1.02e-53

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 183.76  E-value: 1.02e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   3 KMSSDADdILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVydMRP 82
Cdd:PLN02988   4 EMASQSQ-VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGR--AFCAGGDVAAV--VRD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  83 PEVDPKRhkappLALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGA 162
Cdd:PLN02988  79 IEQGNWR-----LGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 163 TYFLSNLPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAvgkiVESLATALERTFSGGETTSELDRNAkdwankvdee 242
Cdd:PLN02988 154 SYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTR----LTALEADLCRIGSNDPTFASTILDA---------- 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 243 lrklekeTSGEVKETPNDLHPHLAVIDRWFVSDDVQEVDLTLNAAAVggrRERERKVAKELLELMRAGcPASLRVTAAML 322
Cdd:PLN02988 220 -------YTQHPRLKPQSAYHRLDVIDRCFSRRTVEEIISALEREAT---QEADGWISATIQALKKAS-PASLKISLRSI 288

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 323 KRVRppvdimnVSGgppppldLARCLRMEFRAVAECISRD---DFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETF 399
Cdd:PLN02988 289 REGR-------LQG-------VGQCLIREYRMVCHVMKGEiskDFVEGCRAILVDKDKN--PKWEPRRLEDMKDSMVEQY 352


                 ....*....
gi 303280852 400 FEPGSREVE 408
Cdd:PLN02988 353 FERVEEEEE 361
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 9-402 1.39e-53

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 184.03  E-value: 1.39e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMrppeVDPK 88
Cdd:PLN02851  42 DQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSGR--AFCSGADVVSLYHL----INEG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  89 RHKAPPLaleFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSN 168
Cdd:PLN02851 116 NVEECKL---FFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSR 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 169 LPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALErtfsggETTSELDRNAKDWANKVDEELRKLek 248
Cdd:PLN02851 193 LPGYLGEYLALTGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLT------DDPAVIEDSLAQYGDLVYPDKSSV-- 264

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 249 etsgevketpndLHpHLAVIDRWFVSDDVQEVDLTLNAAAVGGRRERERKVAKELLElmraGCPASLRVTaamLKRVRPp 328
Cdd:PLN02851 265 ------------LH-KIETIDKCFGHDTVEEIIEALENEAASSYDEWCKKALKKIKE----ASPLSLKVT---LQSIRE- 323

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 303280852 329 vdimnvsgGPPPPLDlaRCLRMEFRAVAECISR---DDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFFEP 402
Cdd:PLN02851 324 --------GRFQTLD--QCLAREYRISLCGVSKwvsGDFCEGVRARLVDKDFA--PKWDPPSLGEVSKDMVDCYFTP 388
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 5-400 1.06e-45

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 162.93  E-value: 1.06e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   5 SSDAD-DILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPp 83
Cdd:PLN02157  32 PEDLDyQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGR--AFCAGGDIVSLYHLRK- 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  84 evdpkrHKAPPLALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGAT 163
Cdd:PLN02157 109 ------RGSPDAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGAS 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 164 YFLSNLPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALERTFSGGETTseLDRNAKdwankvdeel 243
Cdd:PLN02157 183 FNLSHLPGRLGEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESC--LEKCAE---------- 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 244 rKLEKETSGEVKEtpndlhphLAVIDRWFVSDDVQEVDLTLNAAAvggrRERERKVAKELLELMRAGCPASLRVTAAMLK 323
Cdd:PLN02157 251 -VAHPEKTGVIRR--------IDLLEKCFSHDTVEEIIDSLEIEA----GRRKDTWCITTLRRLKESSPLSLKVALRSIR 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 324 RVRPPVdimnvsggppppldLARCLRMEFRAVAECI---SRDDFYEGVRARLVDKGKGdpPAWSPESVEEVGHEDVETFF 400
Cdd:PLN02157 318 EGRLQT--------------LDQCLIREYRMSLQGLigpMSGNFCEGVRARLIDKDEA--PKWDPPSLEKVSEDMVDDYF 381
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 11-215 7.47e-38

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 136.15  E-value: 7.47e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVYDMRPpevdpkrh 90
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG--KAFCAGADLKELAALSD-------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 kAPPLALEFFNREYQMNHQLANARTPHVAImdgvvmgggcgvsIHGA-------------FRVATERTVLAMPECVIGLV 157
Cdd:cd06558   71 -AGEEARAFIRELQELLRALLRLPKPVIAA-------------VNGAalggglelalacdIRIAAEDAKFGLPEVKLGLV 136

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 303280852 158 PDVGATYFLSNLPG-RVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:cd06558  137 PGGGGTQRLPRLVGpARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 11-215 9.03e-34

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 126.82  E-value: 9.03e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVYDMRPPEVdpkrh 90
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG--KAFCAGADLKELAAAADPEE----- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 kapplALEFFNREYQMNHQLANARTPHVAimdgvvmgggcgvSIHGA-------------FRVATERTVLAMPECVIGLV 157
Cdd:COG1024   74 -----ARAFARGLQRLFRALRRLPKPVIA-------------AVNGAalggglelalacdLRIAAEDARFGLPEVRLGLI 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 158 PDVGATYFLSNLPGRvGHA--LALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:COG1024  136 PGGGGTQRLPRLVGL-ARAkeLLLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARL 194
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 9-218 4.58e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 91.85  E-value: 4.58e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAvYDMRPPEVDPK 88
Cdd:PRK06688   5 TDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGR--AFSAGGDIKD-FPKAPPKPPDE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  89 RHKApplaleffnreYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFlsn 168
Cdd:PRK06688  82 LAPV-----------NRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSAL--- 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 303280852 169 LPGRVGHA----LALTGRRVGGYDAKKLGLATH----AIGSSAVGKIVESLAT----ALERT 218
Cdd:PRK06688 148 LPRLIGRAraaeMLLLGEPLSAEEALRIGLVNRvvpaAELDAEADAQAAKLAAgpasALRYT 209
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 9-215 2.62e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 89.79  E-value: 2.62e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSS-VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRPPEVdp 87
Cdd:PRK07657   3 QNISVDYVTPhVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEK-AFCAGADLKERAGMNEEQV-- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  88 kRHkapplALEFFNREYQMNHQLANartPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLS 167
Cdd:PRK07657  80 -RH-----AVSLIRTTMEMVEQLPQ---PVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLP 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 303280852 168 NLPGrVGHA--LALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:PRK07657 151 RLIG-VGRAkeLIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKI 199
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 9-215 1.58e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 79.20  E-value: 1.58e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVK-----AVYDMRPP 83
Cdd:PRK05995   4 ETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG--KAFCAGADLNwmkkmAGYSDDEN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  84 EVDPKRhkappLAleffnreyQMNHQLANARTPHVAimdgvvmgggcgvSIHGA-------------FRVATERTVLAMP 150
Cdd:PRK05995  82 RADARR-----LA--------DMLRAIYRCPKPVIA-------------RVHGDayaggmglvaacdIAVAADHAVFCLS 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 303280852 151 ECVIGLVPDVGATYFLSNLPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:PRK05995 136 EVRLGLIPATISPYVIRAMGERAARRYFLTAERFDAAEALRLGLVHEVVPAEALDAKVDELLAAL 200
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 4-216 5.54e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 74.70  E-value: 5.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   4 MSSDADDILVDAVS--SVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMR 81
Cdd:PRK08138   1 MMSTATDVVLLERPadGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEK--VFAAGADIKEFATAG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  82 PPEVdPKRHKapplaleffNREYQmnhQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVG 161
Cdd:PRK08138  79 AIEM-YLRHT---------ERYWE---AIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAG 145

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 303280852 162 ATYFLSNLPGRVgHAL--ALTGRRVGGYDAKKLGLAthaigsSAVGKIVESLATALE 216
Cdd:PRK08138 146 GTQRLVRAVGKF-KAMrmALTGCMVPAPEALAIGLV------SEVVEDEQTLPRALE 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 17-194 7.54e-15

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 73.93  E-value: 7.54e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   17 SSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPPEVDPKRHKAPPLA 96
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDK--AFCAGADLKEMYGEGPAHQALYRENVLDLW 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   97 LEFFNREYqmnhqlanartPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFlsnLPGRVGHA 176
Cdd:pfam00378  82 TLLYTCPK-----------PVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDR---LPRIIGHS 147

                         170       180
                  ....*....|....*....|..
gi 303280852  177 LA----LTGRRVGGYDAKKLGL 194
Cdd:pfam00378 148 KAmemlLLGRRISAQEALKWGL 169
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
8-204 9.65e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 73.64  E-value: 9.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   8 ADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKavydmrppEVDP 87
Cdd:PRK05980   2 TDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDR-AFSAGADIH--------EFSA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  88 KRHKAPPLAL-EFFNREYQMNHQLANARTPHVAIMDGVVMGG--GCGVSIHGAfrVATERTVLAMPECVIGLVPDVGATY 164
Cdd:PRK05980  73 SVAAGADVALrDFVRRGQAMTARLEAFPKPVIAAVNGLAFGGgcEITEAVHLA--IASERALFAKPEIRLGMPPTFGGTQ 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 303280852 165 FLSNLPGRV-GHALALTGRRVGGYDAKKLGLATHAIGSSAV 204
Cdd:PRK05980 151 RLPRLAGRKrALELLLTGDAFSAERALEIGLVNAVVPHEEL 191
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 17-201 4.92e-13

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 69.16  E-value: 4.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  17 SSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpcLCAGGDVKAVYDMRPPEVDPKRHKAPpla 96
Cdd:PLN02664  16 SSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDH--FCSGIDLKTLNSISEQSSSGDRGRSG--- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  97 lEFFNREYQMNHQLANA----RTPHVAimdgvvmgggcgvSIHGA-------------FRVATERTVLAMPECVIGLVPD 159
Cdd:PLN02664  91 -ERLRRKIKFLQDAITAieqcRKPVIA-------------AIHGAcigggvdivtacdIRYCSEDAFFSVKEVDLAITAD 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 303280852 160 VGAtyfLSNLPGRVGHA----LALTGRRVGGYDAKKLGLATHAIGS 201
Cdd:PLN02664 157 LGT---LQRLPSIVGYGnameLALTGRRFSGSEAKELGLVSRVFGS 199
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
19-194 9.23e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 68.08  E-value: 9.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpcLCAGGDVKAVYDMRPPEVDPKRHKaPPLALE 98
Cdd:PRK06142  16 VAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH--FSYGIDLPAMAGVFGQLGKDGLAR-PRTDLR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  99 FFNREYQMN-HQLANARTPHVAimdgvvmgggcgvSIHGA-------------FRVATERTVLAMPECVIGLVPDVGAty 164
Cdd:PRK06142  93 REILRLQAAiNAVADCRKPVIA-------------AVQGWcigggvdlisacdMRYASADAKFSVREVDLGMVADVGS-- 157

                        170       180       190
                 ....*....|....*....|....*....|....
gi 303280852 165 fLSNLPGRV--GHA--LALTGRRVGGYDAKKLGL 194
Cdd:PRK06142 158 -LQRLPRIIgdGHLreLALTGRDIDAAEAEKIGL 190
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 11-194 1.79e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 67.11  E-value: 1.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVydmrppevdpkrh 90
Cdd:PRK06072   2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGR--AFCVGADLSEF------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 kAPPLALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLP 170
Cdd:PRK06072  67 -APDFAIDLRETFYPIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLT 145

                        170       180
                 ....*....|....*....|....
gi 303280852 171 GRVGHALALTGRRVGGYDAKKLGL 194
Cdd:PRK06072 146 GQRFYEILVLGGEFTAEEAERWGL 169
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 6-194 2.06e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 67.04  E-value: 2.06e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   6 SDADDILVD-AVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMrPPE 84
Cdd:PRK06210   2 MAYDAVLYEvADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGR--GFCAGADMGELQTI-DPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  85 VDPKRHKAPPLALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATY 164
Cdd:PRK06210  79 DGRRDTDVRPFVGNRRPDYQTRYHFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISW 158

                        170       180       190
                 ....*....|....*....|....*....|....
gi 303280852 165 FlsnLPGRVGHA----LALTGRRVGGYDAKKLGL 194
Cdd:PRK06210 159 I---LPRLVGHAnaldLLLSARTFYAEEALRLGL 189
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
22-197 2.83e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 66.44  E-value: 2.83e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  22 VTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVydMRPPeVDPKRHKAPPLaleffn 101
Cdd:PRK07509  16 VRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGG--AFCAGLDVKSV--ASSP-GNAVKLLFKRL------ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 102 reyqmnHQLANA---------RTPHVAImdgvvmgggcgVSIHGA-------------FRVATERTVLAMPECVIGLVPD 159
Cdd:PRK07509  85 ------PGNANLaqrvslgwrRLPVPVI-----------AALEGVcfggglqialgadIRIAAPDTKLSIMEAKWGLVPD 147

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 303280852 160 VGATYFLSNLPGR-VGHALALTGRRVGGYDAKKLGLATH 197
Cdd:PRK07509 148 MAGTVSLRGLVRKdVARELTYTARVFSAEEALELGLVTH 186
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
7-199 3.22e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 66.28  E-value: 3.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   7 DADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPPEVD 86
Cdd:PRK07799   3 GGPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGG--AFCAGMDLKAATKKPPGDSF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  87 PKRHKAPPlALEFFNREYQMNHQL-ANARTPHVAimdgvvmggGCGVSIHGA-FRVATERTVLAMPECVIGLVPDVGATY 164
Cdd:PRK07799  81 KDGSYDPS-RIDALLKGRRLTKPLiAAVEGPAIA---------GGTEILQGTdIRVAGESAKFGISEAKWSLFPMGGSAV 150

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 303280852 165 FL-SNLPGRVGHALALTGRRVGGYDAKKLGLATHAI 199
Cdd:PRK07799 151 RLvRQIPYTVACDLLLTGRHITAAEAKEIGLIGHVV 186
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 11-199 3.47e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 66.15  E-value: 3.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVYDmrppevdpkrh 90
Cdd:PRK06190   6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGAD--PAFCAGLDLKELGG----------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 KAPPLALEFfnREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLP 170
Cdd:PRK06190  73 DGSAYGAQD--ALPNPSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKV 150

                        170       180       190
                 ....*....|....*....|....*....|
gi 303280852 171 G-RVGHALALTGRRVGGYDAKKLGLATHAI 199
Cdd:PRK06190 151 GiGRARRMSLTGDFLDAADALRAGLVTEVV 180
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 4-215 1.47e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 64.55  E-value: 1.47e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   4 MSSDAddILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEwDADKDVKCIVLNGAGERpcLCAGGDVkAVYDMRPP 83
Cdd:PRK08140   1 MMYET--ILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQ-VEDDGARALLLTGAGRG--FCAGQDL-ADRDVTPG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  84 EvdpkrhKAPPLAL---EFFNreyQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDV 160
Cdd:PRK08140  75 G------AMPDLGEsieTFYN---PLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDS 145

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 303280852 161 GATYFlsnLPGRVGHA----LALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:PRK08140 146 GGTWF---LPRLVGMAralgLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHL 201
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 19-198 5.61e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 62.73  E-value: 5.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKlNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPPEvdpkrhKAPPLAL- 97
Cdd:PRK07658  12 VAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGR--FFSAGADIKEFTSVTEAE------QATELAQl 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  98 --EFFNReyqmnhqLANARTPHVAimdgvvmgggcgvSIHGA-------------FRVATERTVLAMPECVIGLVPDVGA 162
Cdd:PRK07658  83 gqVTFER-------VEKFSKPVIA-------------AIHGAalggglelamschIRFATESAKLGLPELNLGLIPGFAG 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 303280852 163 TyflSNLPGRVGHALA----LTGRRVGGYDAKKLGLATHA 198
Cdd:PRK07658 143 T---QRLPRYVGKAKAlemmLTSEPITGAEALKWGLVNGV 179
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 5-203 1.93e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 61.26  E-value: 1.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   5 SSDADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRppe 84
Cdd:PRK06127   7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEK-AFVSGADISQFEESR--- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  85 vdpkrhkAPPLALEFFNR--EYQMNhQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGA 162
Cdd:PRK06127  83 -------SDAEAVAAYEQavEAAQA-ALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDG 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 303280852 163 tyfLSNLPGRVGHALA----LTGRRVGGYDAKKLGLATHAIGSSA 203
Cdd:PRK06127 155 ---VKNLVDLVGPSAAkdlfYTARRFDAAEALRIGLVHRVTAADD 196
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 11-194 3.47e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 60.44  E-value: 3.47e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAgERpCLCAGGDVKAVYDMRPPEVdpkrh 90
Cdd:PRK05862   6 ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EK-AFAAGADIKEMADLSFMDV----- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  91 kapplalefFNREYQMN-HQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATyflSNL 169
Cdd:PRK05862  79 ---------YKGDYITNwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGS---QRL 146

                        170       180
                 ....*....|....*....|....*....
gi 303280852 170 PGRVGHA----LALTGRRVGGYDAKKLGL 194
Cdd:PRK05862 147 TRAVGKAkamdLCLTGRMMDAAEAERAGL 175
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 11-238 3.82e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 62.16  E-value: 3.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   11 ILVDAVSSVRVVTLNRPD-KLNVLSDSMVTRLSELWAEWDADKDVKCIVLNgAGERPCLCAGGDVKAVYDMRPPEvdpkr 89
Cdd:TIGR02441  15 RHYEVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLI-SGKPGSFVAGADIQMIAACKTAQ----- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   90 hkapplALEFFNREYQ-MNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATE--RTVLAMPECVIGLVPDVGATYFL 166
Cdd:TIGR02441  89 ------EVTQLSQEGQeMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 303280852  167 SNLPGrVGHAL--ALTGRRVGGYDAKKLGLathaigssaVGKIVESLATAL----ERTFSGGETTSEldRNAKDWANK 238
Cdd:TIGR02441 163 PKLTG-VPAALdmMLTGKKIRADRAKKMGI---------VDQLVDPLGPGLkpaeENTIEYLEEVAV--KFAQGLANG 228
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 19-194 9.46e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 58.90  E-value: 9.46e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAvydmrppEVDPKRHKAPPLALE 98
Cdd:PRK06494  14 VTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDK-AFSAGNDLKE-------QAAGGKRGWPESGFG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  99 FFNREYQMNHQLAnARTPHVAImdgvvmgggcgvsiHGAFR--------VATERTVLAMPECVIGLVPDVGATYFLS-NL 169
Cdd:PRK06494  86 GLTSRFDLDKPII-AAVNGVAM--------------GGGFElalacdliVAAENATFALPEPRVGLAALAGGLHRLPrQI 150

                        170       180
                 ....*....|....*....|....*
gi 303280852 170 PGRVGHALALTGRRVGGYDAKKLGL 194
Cdd:PRK06494 151 GLKRAMGMILTGRRVTAREGLELGF 175
PLN02600 PLN02600
enoyl-CoA hydratase
 17-199 1.41e-09

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 58.28  E-value: 1.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  17 SSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRPPEVDpkrhkappla 96
Cdd:PLN02600   3 SGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPG-VFCAGADLKERRKMSPSEVQ---------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  97 lEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSNLPGR-VGH 175
Cdd:PLN02600  72 -KFVNSLRSTFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRsRAK 150

                        170       180
                 ....*....|....*....|....
gi 303280852 176 ALALTGRRVGGYDAKKLGLATHAI 199
Cdd:PLN02600 151 ELIFTGRRIGAREAASMGLVNYCV 174
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
13-216 1.56e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 58.11  E-value: 1.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  13 VDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAewDADKDVKCIVLNGAGerPCLCAGGDVKAVYDMRPPEVdpKRHKa 92
Cdd:PRK08150   6 YELDGGVATIGLNRPAKRNALNDGLIAALRAAFA--RLPEGVRAVVLHGEG--DHFCAGLDLSELRERDAGEG--MHHS- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  93 pplaleffnreyQMNH----QLANARTPHVAIMdgvvmgggcgvsiHGA-------------FRVATERTVLAMPECVIG 155
Cdd:PRK08150  79 ------------RRWHrvfdKIQYGRVPVIAAL-------------HGAvvggglelasaahIRVADESTYFALPEGQRG 133

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 303280852 156 LVPDVGATYFLSNLpgrVGHA----LALTGRRVGGYDAKKLGLATHAIGSSavgkivESLATALE 216
Cdd:PRK08150 134 IFVGGGGSVRVPRL---IGVArmtdMMLTGRVYDAQEGERLGLAQYLVPAG------EALDKAME 189
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
19-241 3.33e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 57.67  E-value: 3.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpcLCAGGDVK----AVYDMRPPEvdpkrhkapp 94
Cdd:PRK08258  27 VATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGN--FCSGGDVHeiigPLTKMDMPE---------- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  95 laLEFFNReyqMNHQLANA----RTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLV-PDVGATYFLSNL 169
Cdd:PRK08258  95 --LLAFTR---MTGDLVKAmracPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRI 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 303280852 170 PGRvGHA--LALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALER--TFSGGETTSELdrnAKDWANKVDE 241
Cdd:PRK08258 170 IGQ-GRAseLLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAgpTFAHGMTKTML---HQEWDMGLEE 241
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 8-196 5.18e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 56.66  E-value: 5.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   8 ADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVY--DMRPPEV 85
Cdd:PRK05870   2 MDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG--KAFCAGADLTALGaaPGRPAED 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  86 DPKRHKAPPLAleffnreyqmnhqLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYF 165
Cdd:PRK05870  80 GLRRIYDGFLA-------------VASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWM 146

                        170       180       190
                 ....*....|....*....|....*....|..
gi 303280852 166 LSNLPG-RVGHALALTGRRVGGYDAKKLGLAT 196
Cdd:PRK05870 147 LQRAVGpQVARAALLFGMRFDAEAAVRHGLAL 178
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
7-239 6.65e-09

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 56.29  E-value: 6.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   7 DADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRPPEvd 86
Cdd:PRK05809   2 ELKNVILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEK-AFVAGADISEMKDLNEEE-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  87 pkrhkapplALEFFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFL 166
Cdd:PRK05809  79 ---------GRKFGLLGNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRL 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 303280852 167 SNLPGrVGHA--LALTGRRVGGYDAKKLGLathaigssaVGKIVEslatalertfsggetTSELDRNAKDWANKV 239
Cdd:PRK05809 150 ARIVG-PGKAkeLIYTGDMINAEEALRIGL---------VNKVVE---------------PEKLMEEAKALANKI 199
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 2-75 7.72e-09

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 56.49  E-value: 7.72e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 303280852   2 AKMSSDADDILV-DAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVK 75
Cdd:PRK08139   3 APAAATEAPLLLrEDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAG--KAFCAGHDLK 75
PLN02888 PLN02888
enoyl-CoA hydratase
 2-87 8.40e-09

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 56.30  E-value: 8.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   2 AKMSSDADDILVD-AVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKA---V 77
Cdd:PLN02888   2 MTQTVSENLILVPkSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSG--RAFCSGVDLTAaeeV 79

                         90
                 ....*....|..
gi 303280852  78 Y--DMRPPEVDP 87
Cdd:PLN02888  80 FkgDVKDVETDP 91
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 19-195 2.61e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 54.65  E-value: 2.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWdADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPPEvdpKRHKAPPLALE 98
Cdd:PRK07659  16 VATIMLNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNGR--GFSAGGDIKMMLSSNDES---KFDGVMNTISE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  99 FFNREYQMnhqlanartPHVAImdgvvmgggcgVSIHGA-------------FRVATERTVLAMPECVIGLVPDVGATYF 165
Cdd:PRK07659  90 IVVTLYTM---------PKLTI-----------SAIHGPaaglglsialtadYVIADISAKLAMNFIGIGLIPDGGGHFF 149

                        170       180       190
                 ....*....|....*....|....*....|....
gi 303280852 166 LSNlpgRVGHALA----LTGRRVGGYDAKKLGLA 195
Cdd:PRK07659 150 LQK---RVGENKAkqiiWEGKKLSATEALDLGLI 180
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
22-79 3.38e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 54.66  E-value: 3.38e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 303280852  22 VTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpcLCAGGDVKAVYD 79
Cdd:PRK08272  23 ITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG--FCAGYDLSAYAE 78
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
9-81 3.47e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 54.21  E-value: 3.47e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSD-SMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKavyDMR 81
Cdd:PRK09245   3 DFLLVERDGHIVTLTMNRPETRNALSDnDAVDALVAACAAINADRSVRAVILTGAG--TAFSSGGNVK---DMR 71
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
4-75 4.95e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 53.91  E-value: 4.95e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 303280852   4 MSSDADDILVDAvSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpcLCAGGDVK 75
Cdd:PRK07468   1 MMFETIRIAVDA-RGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKS--FCAGGDLG 69
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 18-194 9.93e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 53.08  E-value: 9.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  18 SVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMR--PPEVdpKRHKappl 95
Cdd:PRK07511  12 STLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGG--FFCAGGNLNRLLENRakPPSV--QAAS---- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  96 aLEffnreyQMNHQLANART---PHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFLSN-LPG 171
Cdd:PRK07511  84 -ID------GLHDWIRAIRAfpkPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARaLPR 156

                        170       180
                 ....*....|....*....|...
gi 303280852 172 RVGHALALTGRRVGGYDAKKLGL 194
Cdd:PRK07511 157 QLATELLLEGKPISAERLHALGV 179
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
7-216 3.01e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 51.53  E-value: 3.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   7 DADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPPEVd 86
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGG--TFCAGMDLKAFARGERPSI- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  87 PKR-----HKAPPlaleffnreyqmnhqlanaRTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVG 161
Cdd:PRK08252  78 PGRgfgglTERPP-------------------RKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGG 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 303280852 162 AtyfLSNLPGRVGHALA----LTGRRVGGYDAKKLGLathaigssaVGKIVES---LATALE 216
Cdd:PRK08252 139 G---LLRLPRRIPYHIAmelaLTGDMLTAERAHELGL---------VNRLTEPgqaLDAALE 188
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
22-81 4.48e-07

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 51.18  E-value: 4.48e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  22 VTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMR 81
Cdd:PRK07327  25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGK--AFSAGGDLALVEEMA 82
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 6-90 4.71e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 51.12  E-value: 4.71e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   6 SDADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVYDMRPPEV 85
Cdd:PRK08290   1 MEYEYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAG--KHFSAGHDLGSGTPGRDRDP 78


                 ....*
gi 303280852  86 DPKRH 90
Cdd:PRK08290  79 GPDQH 83
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 9-94 5.93e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 50.78  E-value: 5.93e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERPC----LCAGGDVKAVYDMRPPE 84
Cdd:PRK08260   4 ETIRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCagadLSAGGNTFDLDAPRTPV 83

                         90
                 ....*....|
gi 303280852  85 VDPKRHKAPP 94
Cdd:PRK08260  84 EADEEDRADP 93
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
9-217 1.05e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 49.79  E-value: 1.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVD---AVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLngAGERPCLCAGGDVK--AVYDMRPP 83
Cdd:PRK06023   3 DHILVErpgAHPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVF--LGTEGCFSAGNDMQdfLAAAMGGT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  84 EVDPKrhkapplALEFFnreyqmnHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGAT 163
Cdd:PRK06023  81 SFGSE-------ILDFL-------IALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSS 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 303280852 164 YFlsnLPGRVGH----ALALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALER 217
Cdd:PRK06023 147 LL---APRLMGHqrafALLALGEGFSAEAAQEAGLIWKIVDEEAVEAETLKAAEELAA 201
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
9-87 1.61e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 49.12  E-value: 1.61e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpcLCAGGDVKAVYDMRPPEVDP 87
Cdd:PRK08259   3 MSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGT--FCAGADLKAVGTGRGNRLHP 79
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
6-194 3.21e-06

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 48.15  E-value: 3.21e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   6 SDADDILVDAVSSVRVVTLNRPdKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDMRPPEV 85
Cdd:PRK06495   1 MMMSQLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVLTGAGK--VFCAGADLKGRPDVIKGPG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  86 DPKRHKapplaleffNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLvpdVGATYF 165
Cdd:PRK06495  78 DLRAHN---------RRTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKH 145

                        170       180       190
                 ....*....|....*....|....*....|...
gi 303280852 166 LSNLpgrVGHALA----LTGRRVGGYDAKKLGL 194
Cdd:PRK06495 146 AMRL---FGHSLTrrmmLTGYRVPAAELYRRGV 175
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
9-216 7.07e-06

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 47.38  E-value: 7.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   9 DDILVDAVSSVRVVTLNRPdKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRPPEVDPK 88
Cdd:PRK03580   3 ESLHTTRNGSILEITLDRP-KANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEK-FFSAGWDLKAAAEGEAPDADFG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  89 RHKAPPLAlEFFNreyqMNhqlanarTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGAtyfLSN 168
Cdd:PRK03580  81 PGGFAGLT-EIFD----LD-------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGG---VLR 145

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 303280852 169 LPGRVGHALA----LTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALE 216
Cdd:PRK03580 146 LPKRLPPAIAnemvMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLV 197
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
7-194 7.63e-06

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 47.42  E-value: 7.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   7 DADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKD-VKCIVLNGAGErpCLCAGGDVKAVYDmRPPEV 85
Cdd:PRK05981   2 QFKKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAeVRCLVLTGAGR--GFCTGANLQGRGS-GGRES 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  86 DPKrhKAPPLALE-FFNreyQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATY 164
Cdd:PRK05981  79 DSG--GDAGAALEtAYH---PFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTW 153

                        170       180       190
                 ....*....|....*....|....*....|.
gi 303280852 165 FLSNLPGRV-GHALALTGRRVGGYDAKKLGL 194
Cdd:PRK05981 154 LLPRLVGKArAMELSLLGEKLPAETALQWGL 184
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 19-194 9.31e-06

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 47.07  E-value: 9.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVydmrpPEVDpkrhkappLALE 98
Cdd:PRK09674  12 VLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNAR--FFAAGADLNEM-----AEKD--------LAAT 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  99 FFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATyflSNLPGRVGHALA 178
Cdd:PRK09674  77 LNDPRPQLWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGT---QRLIRSVGKSLA 153

                        170       180
                 ....*....|....*....|
gi 303280852 179 ----LTGRRVGGYDAKKLGL 194
Cdd:PRK09674 154 sqmvLTGESITAQQAQQAGL 173
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
19-217 1.01e-05

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 46.98  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYDmrpPEVDPKRHKApplale 98
Cdd:PRK07827  16 VATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGG--TFCAGADLSEAGG---GGGDPYDAAV------ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  99 ffNREYQMN---HQLANARTPHVAIMDGVVMGGGCgvSIHGA--FRVATERTVLAMPECVIGLVPDVGATYFLSNLPGRV 173
Cdd:PRK07827  85 --ARAREMTallRAIVELPKPVIAAIDGHVRAGGF--GLVGAcdIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 303280852 174 GHALALTGRRVGGYDAKKLGLATHAigSSAVGKIVESLATALER 217
Cdd:PRK07827 161 AARYYLTGEKFGAAEAARIGLVTAA--ADDVDAAVAALLADLRR 202
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
19-229 1.44e-05

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 47.20  E-value: 1.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPD-KLNVLSDSMVTRLSELWAEWDADKDVKCIVLNgAGERPCLCAGGDVKAVydmrppEVDPKRHKAPPLAl 97
Cdd:PRK11154  16 IAVITIDVPGeKMNTLKAEFAEQVRAILKQLREDKELKGVVFI-SGKPDNFIAGADINML------AACKTAQEAEALA- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  98 effnREYQ-MNHQLANARTPHVAimdgvvmgggcgvSIHGA-------------FRVAT--ERTVLAMPECVIGLVPDVG 161
Cdd:PRK11154  88 ----RQGQqLFAEIEALPIPVVA-------------AIHGAclggglelalachYRVCTddPKTVLGLPEVQLGLLPGSG 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 303280852 162 ATyflSNLPGRVGHALA----LTGRRVGGYDAKKLGLATHAIGSSAVgkivesLATALERTFSGGETTSELD 229
Cdd:PRK11154 151 GT---QRLPRLIGVSTAldmiLTGKQLRAKQALKLGLVDDVVPHSIL------LEVAVELAKKGKPARRPLP 213
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 19-216 3.00e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 45.29  E-value: 3.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKlNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVydmrppeVDPKRHKAPPLALE 98
Cdd:PRK09076  13 VAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEK-FFSAGADLNLF-------ADGDKAVAREMARR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  99 F---FNReyqmnhqLANARTPHVAimdgvvmgggcgvSIHG-------------AFRVATERTVLAMPECVIGLVPDVGA 162
Cdd:PRK09076  84 FgeaFEA-------LSAFRGVSIA-------------AINGyamggglecalacDIRIAEEQAQMALPEASVGLLPCAGG 143

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 303280852 163 TyflSNLPGRVGHALA----LTGRRVGGYDAKKLGLATHAIGSSavgkivESLATALE 216
Cdd:PRK09076 144 T---QNLPWLVGEGWAkrmiLCGERVDAATALRIGLVEEVVEKG------EAREAALA 192
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 22-247 3.18e-05

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 45.38  E-value: 3.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  22 VTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGDVKAVYdmRPPEVDPKR--HKAPPLALEF 99
Cdd:PRK09120  21 VTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGD--AWSAGMDLKEYF--RETDAQPEIlqERIRREAYGW 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 100 FNReyqmnhqLANARTPHVAIMDgvvmgggcGVSIHGAFR--------VATERTVLAMPECVIGLVPDVGATYFLSNLpg 171
Cdd:PRK09120  97 WRR-------LRWYQKPTIAMVN--------GWCFGGGFSplvacdlaIAADEAQFGLSEINWGIPPGGGVSKAMADT-- 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852 172 rVGH--AL--ALTGRRVGGYDAKKLGLATHAIGSS----AVGKIVESLA----TALERTFSGGETTSELdrnakDWANKV 239
Cdd:PRK09120 160 -VGHrdALyyIMTGETFTGRKAAEMGLVNESVPLAqlraRTRELAAKLLeknpVVLRAAKDGFKRVREL-----TWDQAE 233


                 ....*...
gi 303280852 240 DEELRKLE 247
Cdd:PRK09120 234 DYLYAKLE 241
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 11-217 4.77e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 44.73  E-value: 4.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  11 ILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGerPCLCAGGDVKAVydMRPPEVD--PK 88
Cdd:PRK07260   4 IIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANG--KVFSVGGDLVEM--KRAVDEDdvQS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  89 RHKAPPLALEFfnreyqmnhQLANARTPHVAIM--DGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGLVPDVGATYFL 166
Cdd:PRK07260  80 LVKIAELVNEI---------SFAIKQLPKPVIMcvDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLL 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 303280852 167 SNLPG--RVGHaLALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATALER 217
Cdd:PRK07260 151 TRAIGlnRATH-LAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLRR 202
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 19-215 1.77e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 43.10  E-value: 1.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKavyDMrpPEVDPKRHKApplale 98
Cdd:PRK06143  17 VATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEK-AFIGGADIK---EM--ATLDQASAEA------ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  99 FFNREYQMNHQLANARTPHVAIMDGVVMGGGCGVSIHGAFRVATERTVLAMPECVIGlVPDVGATYFLSNLpgrVGHA-- 176
Cdd:PRK06143  85 FISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRL---IGWArt 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 303280852 177 --LALTGRRVGGYDAKKLGLATHAIGSSAVGKIVESLATAL 215
Cdd:PRK06143 161 rwLLLTGETIDAAQALAWGLVDRVVPLAELDAAVERLAASL 201
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 1-76 2.33e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 42.90  E-value: 2.33e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 303280852   1 LAKMSSDADDILVD-AVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpcLCAGGDVKA 76
Cdd:PRK05864   1 VAGYRSTMSLVLVDhPRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG--FSSGADHKS 75
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
5-73 2.48e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 42.63  E-value: 2.48e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 303280852   5 SSDADDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGErpCLCAGGD 73
Cdd:PRK12478   1 TPDFQTLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGR--AFSGGYD 67
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 22-84 5.48e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 41.52  E-value: 5.48e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 303280852  22 VTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVKAVYDMRPPE 84
Cdd:PRK06144  21 ITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDK-AFVAGTDIAQFRAFSTAE 82
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 9-75 7.65e-04

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 41.03  E-value: 7.65e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 303280852   9 DDILVDAVSSVRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGERpCLCAGGDVK 75
Cdd:PRK07396  13 EDILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDK-AFCSGGDQK 78
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 19-195 1.03e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 40.39  E-value: 1.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSElWAEWDADKDVKCIVLNGAGerPCLCAGGDVKA-VYdmrppevdpkrhkapplAL 97
Cdd:PRK07854  10 VLTIELQRPERRNALNAELCEELRE-AVRKAVDESARAIVLTGQG--TVFCAGADLSGdVY-----------------AD 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  98 EFFNREYQMNHQLANARTPHVAimdgvvmgggcgvSIHGA-------------FRVATERTVLAMPECVIGLVPDVGATY 164
Cdd:PRK07854  70 DFPDALIEMLHAIDAAPVPVIA-------------AINGPaigaglqlamacdLRVVAPEAYFQFPVAKYGIALDNWTIR 136

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 303280852 165 FLSNLpgrVGHALA----LTGRRVGGYDAKKLGLA 195
Cdd:PRK07854 137 RLSSL---VGGGRAramlLGAEKLTAEQALATGMA 168
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
19-64 1.49e-03

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 39.94  E-value: 1.49e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 303280852  19 VRVVTLNRPDKLNVLSDSMVTRLSELWAEWDADKDVKCIVLNGAGE 64
Cdd:PRK06563   9 VLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGE 54
PLN02921 PLN02921
naphthoate synthase
 22-73 1.52e-03

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 40.54  E-value: 1.52e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 303280852  22 VTLNRPDKLNVLSDSMVTRLSelWAEWDA--DKDVKCIVLNGAGErPCLCAGGD 73
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQ--RAFNDArdDSSVGVIILTGKGT-KAFCSGGD 130
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 6-220 6.64e-03

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 38.08  E-value: 6.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852   6 SDADDILVDAVSSVRVVTLNRPDKLNVLS----DSMVTRLSELwaewdADKDVKCIVLNGAGERPCLCAGGDVKavyDMR 81
Cdd:PRK11423   1 MSMQYVNVVTINKIATITFNNPAKRNALSkvliDDLMQALSDL-----NRPEIRVVILRAPSGSKVWSAGHDIH---ELP 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 303280852  82 PPEVDPKRHKAPplaLEFFNREYQMNHqlanarTPHVAIMDGVVMGggcgvsihGAFR--------VATERTVLAMPECV 153
Cdd:PRK11423  73 SGGRDPLSYDDP---LRQILRMIQKFP------KPVIAMVEGSVWG--------GAFElimscdliIAASTSTFAMTPAN 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 303280852 154 IGlVP--DVGATYFLSNLPGRVGHALALTGRRVGGYDAKKLGLATHAIGSSAvgkiVESLATALERTFS 220
Cdd:PRK11423 136 LG-VPynLSGILNFTNDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEE----LEDFTLQMAHHIS 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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