|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
60-1129 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 2032.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 60 DGAEKKMSTERRDKLLGIEKIIQKRWEDAKIFEVDASDEPPKPGEKYFGNFPYPYMNGVLHLGHAFSLSKL---AAFQRL 136
Cdd:PLN02959 1 MMAEGGKSTARRDRLLEIEVAVQKWWEEEKVFEAEAGDEPPKPGEKFFGNFPYPYMNGLLHLGHAFSLSKLefaAAYHRL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 137 CGTKVLLPMGFHCTGMPIKACADKLVRESEEFGCPPVFPTEVTDEAPAPVANKE----EVPVEVKFKAKKSKAVAKSGAS 212
Cdd:PLN02959 81 RGANVLLPFAFHCTGMPIKASADKLAREIQQYGNPPVFPEEDEDEAAAVAAAKAeaeaAAAPPDKFKGKKSKAVAKSGTQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 213 KYQWTIMRSLGLEDDEIAKFRDPLYWLEYFPPIAKNDLKFFGLSCDWRRSFITTEANPYYDSFVRWQFEHLREKKKVGKD 292
Cdd:PLN02959 161 KYQWEIMRSFGLPDSEIAKFQDPYHWLSYFPPLAKEDLKAFGLGCDWRRSFITTDVNPYYDAFVRWQFRKLKKKGKIVKD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 293 LRYAIYSPLDRQPCADHDRASGEGVAPQEYVLIKMEVQPPFTGKLKPLEGKKVFLAAATLRPETMYGQTNAWVLADGDYG 372
Cdd:PLN02959 241 KRYTIYSPLDGQPCADHDRASGEGVGPQEYVLIKMEVLPPFPGKLKALEGKKVFLAAATLRPETMYGQTNCWVLPDGKYG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 373 AYEVSATEVFVVTARAALNMAYQNLSRVPQQPTCLVELKGQDLIGLTVVSPLAKNPVVYVLPMLNIKTDKGTGVVTSVPS 452
Cdd:PLN02959 321 AYEINDTEVFILTARAALNLAYQNFSKVPGKPTCLVELTGYDLIGLPLKSPLAFNEVIYALPMLTILTDKGTGVVTSVPS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 453 DSPDDYMALSDLKSKPALRAKFNVQDEWVLPFEVLPIINVPEFGDKSAEAVCISMKIKSQNNRDDLEAAKKMTYLKGFTD 532
Cdd:PLN02959 401 DSPDDYMALSDLKAKPALRAKYGVKDEWVLPFEVVPIINIPEFGDKSAEKVCEDLKIKSQNDKEKLAEAKRLTYLKGFTD 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 533 GKMLVGDYARMKVQEAKPLIKKLLVESGQAVIYSEPEKKVISRSGDECVVALTDQWYLQYAEEEWKSQAEKCLTQMELYS 612
Cdd:PLN02959 481 GTMLVGEYAGRKVQEAKPLIKKKLIEAGQAILYSEPEKKVMSRSGDECVVALTDQWYLTYGEEEWKKKAEKCLSKMNLYS 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 613 DETRRLFEHALGWLNQWACSRSFGLGTKFPWDQDFLIESLSDSTIYMAYYTLAHILQEGDLYGKGDHAVKPNQMTRNVWD 692
Cdd:PLN02959 561 DETRHGFEHTLGWLNQWACSRSFGLGTRIPWDEQFLIESLSDSTIYMAYYTVAHLLQGGDMYGKDKSSIKPEQMTDEVWD 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 693 FVFGMGPLPE-SEIPVETLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWPRSFRCNGFLLLNGEKMA 771
Cdd:PLN02959 641 FVFCGGPLPKsSDIPAELLEKMKQEFEYWYPFDLRVSGKDLIQNHLTFAIYNHTAIWAEEHWPRGFRCNGHLMLNSEKMS 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 772 KSTGNFLTIRDAVSDFSADATRFGLADAGDSVDDANFVKLTANSAILRLTKEMAWMsDEVIAAEKDLRKGSPTTFADRVF 851
Cdd:PLN02959 721 KSTGNFLTLRQAIEEFSADATRFALADAGDGVDDANFVFETANAAILRLTKEIAWM-EEVLAAESSLRTGPPSTYADRVF 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 852 ENEINIAINQTERNYKALMFREALKSGFYDLQIARDEYRLACSSLGMNRDLIFRFADVQTRLLTPICPHYAEYVRSEIFH 931
Cdd:PLN02959 800 ENEINIAIAETEKNYEAMMFREALKSGFYDLQAARDEYRLSCGSGGMNRDLVWRFMDVQTRLITPICPHYAEHVWREILK 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 932 QEGFAVTAGWPASGTPDLTLQRANKFFQSILADFRKALQKHLAASKKAKKGQA-AVPPAAPLAGLIYVAEKYEGWKEESL 1010
Cdd:PLN02959 880 KEGFAVTAGWPVAGEPDLTLKRANKYLQDSIVSFRKLLQKQLAGSKKAKKGGApVTLPEKKLAGLIYVAEKYDGWKEECL 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 1011 KILQSCYDSGSKTFTSDVEILSRLRESSVGQSGDFKQIQKKCMPFVKFKKDETLSVGPQALELRLPFDERWVFEENLELI 1090
Cdd:PLN02959 960 RILQSKFDSQSRTFAPDAEILEALKESSVGQEANFKQVQKLCMPFVKFKKDEAIAVGPQALDLKLPFDEIEVLQENLELI 1039
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*
gi 1376981756 1091 KAQLGLESVMVVPVSSSSSGKIAAAAQAA------SPGSPVIVFV 1129
Cdd:PLN02959 1040 KRQLGLEEVEILSASDPDAVAKAGAHASLlkqnppSPGNPVAIFV 1084
|
|
| leuS_arch |
TIGR00395 |
leucyl-tRNA synthetase, archaeal and cytosolic family; The leucyl-tRNA synthetases belong to ... |
77-1128 |
0e+00 |
|
leucyl-tRNA synthetase, archaeal and cytosolic family; The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both archaeal and cytosolic eukaryotic leucyl-tRNA synthetases; the eubacterial and mitochondrial forms differ so substantially that some other tRNA ligases score higher by this model than does any eubacterial LeuS. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273056 [Multi-domain] Cd Length: 938 Bit Score: 805.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 77 IEKIIQKRWEDAKIFEVDASDEppkpgEKYFGNFPYPYMNGVLHLGHAFSLSK---LAAFQRLCGTKVLLPMGFHCTGMP 153
Cdd:TIGR00395 3 IEKKWQKRWEEAHIFEADPDDR-----EKFFLTMAYPYLNGVMHAGHCRTFTIpevSARFERMKGKNVLFPLGFHVTGTP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 154 IKACADKLVRESEEFGcppvfptEVTDEAPApvankeeVPVEvkfkakkskavaksgaskyqwtimrslgleddEIAKFR 233
Cdd:TIGR00395 78 ILGLAELIKRRDELTI-------KNYTEVHA-------IPRE--------------------------------ELLKFT 111
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 234 DPLYWLEYFPPIAKNDLKFFGLSCDWRRSFITTEanPYYDSFVRWQFEHLREKKKVGKDLRYAIYSPLDRQPCADHDRAS 313
Cdd:TIGR00395 112 DPEYIVEYFSREAESACKSMGYSIDWRRSFKTTD--PYYDRFIEWQMNKLKELGLIVKGEHPVRYCPKDGNPVEDHDLLS 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 314 GEGVAPQEYVLIKMEvqppftgklkpLEGKKVFLAAATLRPETMYGQTNAWVLADGDYGAYEVSAtEVFVVTARAALNMA 393
Cdd:TIGR00395 190 GEGVTIVEYILIKFE-----------LEDGAFYFVAATLRPETVYGVTNCWVNPTITYVIAEVGG-EKWITSKEAFENLS 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 394 YQNLSRVPqqptcLVELKGQDLIGLTVVSPLAkNPVVYVLPMLNIKTDKGTGVVTSVPSDSPDDYMALSDLKSKPALRAK 473
Cdd:TIGR00395 258 YQKLKYKP-----IEEVPGKQFIGKKVHNPVV-GPEVPILPAEFVDTTKGTGVVMSVPAHAPDDYIALEDLLHDPEYLGI 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 474 FNVQDEwvlpFEVLPIINVPEFGDKSAEAVCISMKIKSQNNRDDLEAAKKMTYLKGFTDGKMLVG--DYARMKVQEAKPL 551
Cdd:TIGR00395 332 KPVVID----IEPVPLIHTDGYGDLPAKEIVEEKGIKSQKDKNLLEEATKILYKEEYHTGVMIYNipPYKGMKVSEAKEK 407
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 552 IKKLLVESGQAVIYSEP-EKKVISRSGDECVV-ALTDQWYLQYAEEEWKSQAEKCLTQMELYSDETRRLFEHALGWLNQW 629
Cdd:TIGR00395 408 VKADLIDAGLADVMYEFsESPVICRCGTDCIVkVVEDQWFVKYSDESWKELAHECLEGMRIIPEEVKNAFEGKIDWLKDW 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 630 ACSRSFGLGTKFPWDQDFLIESLSDSTIYMAYYTLAHILQEGDLygkgdhavKPNQMTRNVWDFVF-GMGPLPESEIPVE 708
Cdd:TIGR00395 488 ACCRRYGLGTRLPWDEKWLIESLSDSTIYMAYYTIAHYLNKDYY--------GNEQMTDEFFDYIFlGKGDVKNTNIPLP 559
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 709 TLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFS 788
Cdd:TIGR00395 560 AIQKLRREFEYWYPLDWRISGKDLIPNHLTFYIFHHVAIFPEKFWPRGIVVNGYVMLEGKKMSKSKGNVLTLEQAVEKFG 639
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 789 ADATRFGLADAGDSVDDANFVKLTANSAILRLTKEMAWMsdEVIAAEKDLRKGSPTTFADRVFENEINIAINQTERNYKA 868
Cdd:TIGR00395 640 ADVARLYIADAAETVQDADWKESEVEGTILRLERLYEFA--EEITKESNLETGEETSFIDRWLESRMNAAIKETYEAMEN 717
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 869 LMFREALKSGFYDLQIARDEYRLAcsSLGMNRDLIFRFADVQTRLLTPICPHYAEYVRSEIFHqEGFAVTAGWPASGTP- 947
Cdd:TIGR00395 718 FQTRKAVKYALFDLQADVDWYRRR--GGVNHKDVLARYLETWIKLLAPFAPHFAEEMWEEVGN-EGFVSLAKFPEASEPa 794
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 948 -DLTLQRANKFFQSILADFRKAlqKHLAASKKAKKgqaavppaaplagLIYVAEKyegWKEESLKILQscyDSGSKTFTS 1026
Cdd:TIGR00395 795 vDKEVEAAEEYLRNLVRDIQEI--AKIDASKPKRV-------------YLYTSED---WKSQCLKIVA---ELFGEDTGE 853
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 1027 DVEILSRLREssvgqsgdfkqIQKKCMPFVKFKKDETLSVGPQALELrlpFDERWVFEENLELIKAQLGLESVMVVPVSS 1106
Cdd:TIGR00395 854 DMKKVMEEPE-----------ERKRGKEVISLVKQIIKDEKKEDELQ---ISEIEVLKAAARFIKKEVGALVIIEFSADS 919
|
1050 1060
....*....|....*....|..
gi 1376981756 1107 SSSGKiaaaAQAASPGSPVIVF 1128
Cdd:TIGR00395 920 FPENK----KRNAVPGKPAIYL 937
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
119-1097 |
0e+00 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 725.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 119 LHLGHAFSLSK---LAAFQRLCGTKVLLPMGFHCTGMPIKACADKlvreseefgcppvfptevtdeapapVANKEEvpve 195
Cdd:PRK12300 1 LHVGHGRTYTIgdvIARYKRMRGYNVLFPMAFHVTGTPILGIAER-------------------------IARGDP---- 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 196 vkfkakkskavaksgasKYQWTIMRSLGLEDDEIAKFRDPLYWLEYFPPIAKNDLKFFGLSCDWRRSFITTEanPYYDSF 275
Cdd:PRK12300 52 -----------------ETIELYKSLYGIPEEELEKFKDPEYIVEYFSEEAKEDMKRIGYSIDWRREFTTTD--PEYSKF 112
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 276 VRWQFEHLREKKKVGKDLRYAIYSPLDRQPCADHDRASGEGVAPQEYVLIKmevqppFTgklkplEGKKVFLAAATLRPE 355
Cdd:PRK12300 113 IEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVGDHDLLDGEEPEIVEYTLIK------FE------ESEDLILPAATLRPE 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 356 TMYGQTNAWVLADGDYGAYEVSAtEVFVVTARAALNMAYQNLS-RVpqqptcLVELKGQDLIGLTVVSPLAKNPVVyVLP 434
Cdd:PRK12300 181 TIFGVTNLWVNPDATYVKAEVDG-EKWIVSKEAAEKLSFQDRDvEI------IEEIKGSELIGKKVKNPVTGKEVP-ILP 252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 435 MLNIKTDKGTGVVTSVPSDSPDDYMALSDLKSKPALRAKFnvqdewvlpfEVLPIINVPEFGDKSAEAVCISMKIKSQNN 514
Cdd:PRK12300 253 ADFVDPDNGTGVVMSVPAHAPYDYVALRDLKKNKELLDVI----------EPIPLIEVEGYGEFPAKEVVEKLGIKSQED 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 515 RDdLEAAKKMTYLKGFTDGKML--VGDYARMKVQEAKPLIKKLLVESGQA-VIYSEPEKKVISRSGDECVVA-LTDQWYL 590
Cdd:PRK12300 323 PE-LEEATKEVYRAEFHKGVLKenTGEYAGKPVREAREKITKDLIEKGIAdIMYEFSNRPVYCRCGTECVVKvVKDQWFI 401
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 591 QYAEEEWKSQAEKCLTQMELYSDETRRLFEHALGWLNQWACSRSFGLGTKFPWDQDFLIESLSDSTIYMAYYTLAHILQE 670
Cdd:PRK12300 402 DYSDPEWKELAHKALDNMEIIPEEYRKEFENTIDWLKDRACARRRGLGTRLPWDEEWIIESLSDSTIYMAYYTIAHKIRE 481
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 671 GDLygkgdhavKPNQMTRNVWDFVF-GMGPLPE----SEIPVETLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHT 745
Cdd:PRK12300 482 YGI--------KPEQLTPEFFDYVFlGKGDPEEvskkTGIPKEILEEMREEFLYWYPVDWRHSGKDLIPNHLTFFIFNHV 553
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 746 AMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDSVDDANFVKLTANSAILRLTK--E 823
Cdd:PRK12300 554 AIFPEEKWPRGIVVNGFVLLEGKKMSKSKGNVIPLRKAIEEYGADVVRLYLTSSAELLQDADWREKEVESVRRQLERfyE 633
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 824 MAwmsDEVIAAEKDlrkgSPTTFADRVFENEINIAINQTERNYKALMFREALKSGFYDLQIARDEYRLACSslGMNRDLI 903
Cdd:PRK12300 634 LA---KELIEIGGE----EELRFIDKWLLSRLNRIIKETTEAMESFQTRDAVQEAFYELLNDLRWYLRRVG--EANNKVL 704
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 904 FRFADVQTRLLTPICPHYAEyvrsEIFHQ---EGFAVTAGWPASG--TPDLTLQRANKFFQSILADFRKALQkhlAASKK 978
Cdd:PRK12300 705 REVLEIWIRLLAPFTPHLAE----ELWHKlggEGFVSLEKWPEPDesKIDEEAELAEEYVKRLIEDIREILK---VAKIK 777
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 979 AKKgqaavppaaplaGLIYVAEKyegWKEESLKILQSCYDSGS--KTFTSDVEILSRLRESSvgqsgdfkQIQKKCMPFV 1056
Cdd:PRK12300 778 PKK------------VYIYVAPD---WKYEVLEIAAENGDVKEaiKELMKDEELRKHGKEVA--------KLAQKIVKEV 834
|
970 980 990 1000
....*....|....*....|....*....|....*....|.
gi 1376981756 1057 KFKKDETLSVgpqaleLRLPFDERWVFEENLELIKAQLGLE 1097
Cdd:PRK12300 835 LKLDKEVRKL------ILKNIDEEEVLEEAKDFLEKELGVE 869
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
583-809 |
7.79e-68 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 230.60 E-value: 7.79e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 583 ALTDQWYLQYAEEEWKSQAEKCLTQMELYSDETRRLFEHALGwlnqwaCSRSFGLGTKFPWDqdFLIESLSDSTIYMAYY 662
Cdd:cd00812 127 KLLDQWFLKYSETEWKEKLLKDLEKLDGWPEEVRAMQENWIG------CSRQRYWGTPIPWT--DTMESLSDSTWYYARY 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 663 TLAHILQEGDLYgkgdhavkpnqmtrnvwdfvfgmgplpeseipveTLKRMKKEFDYWYPFDLRVSGKDLIQNHLTFSIY 742
Cdd:cd00812 199 TDAHNLEQPYEG----------------------------------DLEFDREEFEYWYPVDIYIGGKEHAPNHLLYSRF 244
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1376981756 743 NHTAMFPEER----WPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDsvDDANFV 809
Cdd:cd00812 245 NHKALFDEGLvtdePPKGLIVQGMVLLEGEKMSKSKGNVVTPDEAIKKYGADAARLYILFAAP--PDADFD 313
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
808-929 |
1.46e-36 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 133.87 E-value: 1.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 808 FVKLTANSAILRLTKEMAWMSdEVIAAEKDLrkgSPTTFADRVFENEINIAINQTERNYKALMFREALKSGFYDLQIARD 887
Cdd:cd07959 1 FREEEANSAILRLERFYELAE-ELIETEGEL---EELTFIDRWLLSRLNRLIKETTEAYENMQFREALKEGLYELQNDLD 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1376981756 888 EYRLACSSlGMNRDLIFRFADVQTRLLTPICPHYAEYVRSEI 929
Cdd:cd07959 77 WYRERGGA-GMNKDLLRRFIEVWTRLLAPFAPHLAEEIWHEL 117
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
81-808 |
1.14e-29 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 125.99 E-value: 1.14e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 81 IQKRWEDAKIFEvdASDEPPKPGEKYFGNFPYPYMNGVLHLGHAFSLS---KLAAFQRLCGTKVLLPMGFHCTGMPIKAC 157
Cdd:pfam00133 2 IYEFWDEQGYFK--PELEKRKGKPSFTIHDGPPNATGSLHIGHALAKTlkdIVIRYKRMKGYYVLWVPGWDHHGLPTEQV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 158 ADKLVRESEEfgcppvfptevtdeapapvankeevpvevkfkakkskavaksgaskyqwTIMRSLGLEddeiaKFRDPLY 237
Cdd:pfam00133 80 VEKKLGIKEK-------------------------------------------------KTRHKYGRE-----EFREKCR 105
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 238 -WLEYFPPIAKNDLKFFGLSCDWRRSFITTEanPYYDSFVRWQFEHLREKKKVGKDLRYAIYSPLDRQPCADhdrasgeg 316
Cdd:pfam00133 106 eWKMEYADEIRKQFRRLGRSIDWDREYFTMD--PELEAAVWEVFVRLHDKGLIYRGKKLVNWSPALNTALSN-------- 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 317 vAPQEYvlikMEVQPPFTGKLKPL-EGKKVFLAAATLRPETMYGQTNAWVLADGDYGAyevsaTEVFVVTARAALNMAYQ 395
Cdd:pfam00133 176 -LEVEY----KDVKGPSIHVAFPLaDDEGASLVIWTTTPWTLPGNTAVAVNPEFDYVI-----TGEGYILAEALLKSLYK 245
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 396 NLSrvpqQPTCLVELKGQDLIGLTVVSPLA--KNPVV---YVlpmlniKTDKGTGVVTSVPSDSPDDYmalsdlkskpAL 470
Cdd:pfam00133 246 KGT----DKKILEDFRGKELEGKEAIHPFVnrEIPIItddYV------DMEFGTGAVHIAPAHGENDY----------EV 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 471 RAKFNvqdewvlpfevLPIINVpefgdksaeavcismkiksqnnrddleaakkMTYLKGFTDGkmlVGDYARMKVQEAKP 550
Cdd:pfam00133 306 GQRHN-----------LEVINP-------------------------------VDDDGTFTEE---APDFQGVYRFDARK 340
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 551 LIKKLLVESGqAVIYSEPEKKVI---SRSGDECVVALTDQWYLQYaeEEWKSQAEKCLTQMELYSDETRRLFEHALGWLN 627
Cdd:pfam00133 341 KIVELLTEKG-LLLKIEPFTHSYpfcWRSGTPIIPRATPQWFVRM--DELADQALEAVEKVQFVPKSGEKRYFNWLANIQ 417
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 628 QWACSRSFGLGTKFP-W-DQDFLIESLSDSTIYM-AYYTLAHILQEGDLYGKGDHAVKPNQMTR---NVWDFVFGMGPLP 701
Cdd:pfam00133 418 DWCISRQRWWGHPIPaWvSKDTEEVVCRGELFELvAGRFEEEGSIKWLHREAKDKLGYGKGTLEqdeDVLDTWFSSGSWP 497
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 702 ES--EIPVETlkrmKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWpRSFRCNGFLL-LNGEKMAKSTGNFL 778
Cdd:pfam00133 498 FStlGWPFVN----TEEFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGSVPF-KNVLVHGLVRdEQGRKMSKSLGNVI 572
|
730 740 750
....*....|....*....|....*....|
gi 1376981756 779 TIRDAVSDFSADATRFGLADAgDSVDDANF 808
Cdd:pfam00133 573 DPLDVIDKYGADALRLWLANS-DYGRDINL 601
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
105-292 |
1.74e-27 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 114.27 E-value: 1.74e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 105 KYFGNFPYPYMNGVLHLGHAFSLSK---LAAFQRLCGTKVLLPMGFHCTGMPIKACADKLVreseefgcppvfptevtde 181
Cdd:cd00812 1 KFYILVMFPYPSGALHVGHVRTYTIgdiIARYKRMQGYNVLFPMGFDAFGLPAENAAIKIG------------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 182 apapvankeevpvevkfkakkskavaksgaskyqwtimrslgleddeiakfRDPLYWLEYFPPIAKNDLKFFGLSCDWRR 261
Cdd:cd00812 62 ---------------------------------------------------RDPEDWTEYNIKKMKEQLKRMGFSYDWRR 90
|
170 180 190
....*....|....*....|....*....|.
gi 1376981756 262 SFITTeaNPYYDSFVRWQFEHLREKKKVGKD 292
Cdd:cd00812 91 EFTTC--DPEYYKFTQWLFLKLYEKGLAYKK 119
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
77-963 |
4.38e-25 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 112.84 E-value: 4.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 77 IEKIIQKRWEDAKIFEVDASdeppKPGEKYFGNFPYPYMNGVLHLGHAFSLS---KLAAFQRLCGTKVLLPMGFHCTGMP 153
Cdd:TIGR00422 10 VEKKWYKKWEKSGFFKPDGN----SNKPPFCIDIPPPNVTGSLHIGHALNWSiqdIIARYKRMKGYNVLWLPGTDHAGIA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 154 IKACADKLVREseefgcppvfptevtdeapapvankeevpvevkfkakkskavakSGASKYQwtimrsLGLEddeiaKFR 233
Cdd:TIGR00422 86 TQVKVEKKLGA--------------------------------------------EGKTKHD------LGRE-----EFR 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 234 DPLY-WLEYFPPIAKNDLKFFGLSCDWRRSFITTEANPYY---DSFVRWQFehlrekkkvgKDLRYAIYSPLDRQPcadh 309
Cdd:TIGR00422 111 EKIWeWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKavkEAFVRLYE----------KGLIYRGEYLVNWDP---- 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 310 drASGEGVAPQEyvLIKMEVQPPFTGKLKPLE-GKKVFLAAATLRPETMYGQTNAWVLADGDygayevsatevfvvtara 388
Cdd:TIGR00422 177 --KLNTAISDIE--VEYKEVKGKLYYIRYPLAnGSKDYLVVATTRPETMFGDTAVAVHPEDE------------------ 234
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 389 alnmayqnlsrvpqqptclvelKGQDLIGLTVVSPL--AKNPVV---YVLPmlniktDKGTGVVTSVPSDSPDDYmalsd 463
Cdd:TIGR00422 235 ----------------------RYKHLIGKKVILPLtgRKIPIIadeYVDM------EFGTGAVKVTPAHDFNDY----- 281
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 464 lkskpalrakfnvqdEWvlpfevlpiinvpefgdksaeavcismkiksqNNRDDLEAAKKMTYlkgftDGKM--LVGDYA 541
Cdd:TIGR00422 282 ---------------EW--------------------------------GKRHNLEFINILDE-----DGLLneNAGKYQ 309
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 542 RMKVQEAKPLI------KKLLVES---GQAVIYSEpekkvisRSGDECVVALTDQWYLqyAEEEWKSQAEKCL--TQMEL 610
Cdd:TIGR00422 310 GLTRFEARKKIvedlkeEGLLVKIephTHNVGTCW-------RSGTVVEPLLSKQWFV--KVEKLADKALEAAeeGEIKF 380
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 611 YSDETRRLFEHALGWLNQWACSRSFGLGTKFPwdqdflieslsdstiymAYYtlahILQEGDLY--GKGDHAVKPNQMTR 688
Cdd:TIGR00422 381 VPKRMEKRYLNWLRNIKDWCISRQLIWGHRIP-----------------VWY----CKECGEVYvaKEEPLPDDKTNTGP 439
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 689 N--------VWDFVFGMGPLPESeipveTLK--RMKKEFDYWYPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWPRSFr 758
Cdd:TIGR00422 440 SveleqdtdVLDTWFSSSLWPFS-----TLGwpDETKDLKKFYPTDLLVTGYDIIFFWVARMIFRSLALTGQVPFKEVY- 513
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 759 CNGFLL-LNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDSVDDANF----VKLTANSA---------ILRLTKEM 824
Cdd:TIGR00422 514 IHGLVRdEQGRKMSKSLGNVIDPLDVIEKYGADALRFTLASLVTPGDDINFdwkrVESARNFLnklwnasrfVLMNLSDD 593
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 825 awmsdeviaaeKDLRKGS-PTTFADRVFENEINIAINQTER---NYKalmFREALKS-------GFYDLQIARDEYRLAC 893
Cdd:TIGR00422 594 -----------LELSGGEeKLSLADRWILSKLNRTIKEVRKaldKYR---FAEAAKAlyefiwnDFCDWYIELVKYRLYN 659
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1376981756 894 SSLGMNRDLIFRFA---DVQTRLLTPICPHYAEYVRSEIFHQEGFAVTAGWPASgTPDLTLQRANKFFQSILA 963
Cdd:TIGR00422 660 GNEAEKKAARDTLYyvlDKALRLLHPFMPFITEEIWQHFKEGADSIMLQSYPVV-DAEFVDEEAEKAFELLKE 731
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
569-794 |
1.14e-24 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 105.96 E-value: 1.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 569 EKKVISRsgDECVVALTDQWYLQYaeEEWKSQAEKCLTQMELYSDETRRLFEHALGWLNQWACSRSFGLGTKFPWDqdfL 648
Cdd:cd00668 125 EKGLIYR--GTHPVRITEQWFFDM--PKFKEKLLKALRRGKIVPEHVKNRMEAWLESLLDWAISRQRYWGTPLPED---V 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 649 IESLSDSTIYMAYYTlahilqegdlygkgdhavkpnqmtrnvwdfvfgmGPLPEseipvetlkrmKKEFDYWYPFDLRVS 728
Cdd:cd00668 198 FDVWFDSGIGPLGSL----------------------------------GYPEE-----------KEWFKDSYPADWHLI 232
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1376981756 729 GKDLIQNHLTFSIYNHTAMFpEERWPRSFRCNGFLLLN-GEKMAKSTGNFLTIRDAVSDFSADATRF 794
Cdd:cd00668 233 GKDILRGWANFWITMLVALF-GEIPPKNLLVHGFVLDEgGQKMSKSKGNVIDPSDVVEKYGADALRY 298
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
76-942 |
7.71e-12 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 69.84 E-value: 7.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 76 GIEKIIQKRWEDAKIFEVDAS--------DEPPkpgekyfgnfpyPYMNGVLHLGHAFSLSK---LAAFQRLCGTKVLLP 144
Cdd:PRK13208 14 ELEEKWQKIWEEEGTYKFDPDerkpvysiDTPP------------PTVSGSLHIGHVFSYTHtdfIARYQRMRGYNVFFP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 145 MGFHCTGMPIKacadklVRESEEFGcppvfpteVTdeapapvanKEEVPVEvkfkakkskavaksgasKY-----QWTim 219
Cdd:PRK13208 82 QGWDDNGLPTE------RKVEKYYG--------IR---------KDDISRE-----------------EFielcrELT-- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 220 rslgleDDEIAKFRdplywleyfppiakNDLKFFGLSCDWRRSFITTEanPYY-----DSFVRwqfehLREKKKVGKDLR 294
Cdd:PRK13208 120 ------DEDEKKFR--------------ELWRRLGLSVDWSLEYQTIS--PEYrrisqKSFLD-----LYKKGLIYRAEA 172
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 295 YAIYSPLDRQPCADhdrasgegvAPQEYVlikmevqpPFTGKL-----KPLEGKKVFLaaATLRPETMyGQTNAwVLA-- 367
Cdd:PRK13208 173 PVLWCPRCETAIAQ---------AEVEYR--------EREGKLnyikfPVEDGEEIEI--ATTRPELL-PACVA-VVVhp 231
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 368 -DGDYgayevsatevfvvtaraalnmayqnlsrvpqqptclvelkgQDLIGLTVVSPLAKNPVVyVLPMLNIKTDKGTGV 446
Cdd:PRK13208 232 dDERY-----------------------------------------KHLVGKTAIVPLFGVEVP-ILADPLVDPDFGTGA 269
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 447 VtsvpsdspddyMALS--DLkskpalrakfnvQD-EWV----LPfeVLPIInvpefgDKsaeavcismkiksqnnrddle 519
Cdd:PRK13208 270 V-----------MICTfgDK------------TDvTWWrelnLP--TRIII------DE--------------------- 297
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 520 aakkmtylkgftDGKML--VGDYARMKVQEAKPLIKKLLvESGQAVIysEPEK-----KVISRSGD--ECVValTDQWYL 590
Cdd:PRK13208 298 ------------DGRMTeaAGKLAGLTIEEARKKIVEDL-KSGGLLG--KQEPikhnvKFCERCDTplEILV--TRQWFI 360
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 591 QYAE--EEWKSQAEKcltqMELYSDETRRLFEHalgWLNQ----WACSRSFGLGTKFP-WdqdfliESLSDSTIYMAyyt 663
Cdd:PRK13208 361 KVLDlkEELLERGKE----INWYPEHMRVRLEN---WIEGlnwdWCISRQRYFGTPIPvW------YCKDCGHPILP--- 424
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 664 lahilQEGDLygkgdhAVKPNQMT--------RNVWDFVfgmgplPE---------SEIPVETLKRMKKEFDYW---YPF 723
Cdd:PRK13208 425 -----DEEDL------PVDPTKDEppgykcpqCGSPGFE------GEtdvmdtwatSSITPLIVTGWERDEDLFekvFPM 487
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 724 DLRVSGKDLIQNHLTFSI---YNHTAMFPeerWpRSFRCNGFLL-LNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADA 799
Cdd:PRK13208 488 DLRPQGHDIIRTWLFYTIlraYLLTGKLP---W-KNIMISGMVLdPDGKKMSKSKGNVVTPEELLEKYGADAVRYWAASA 563
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 800 --G-DSVDDANFVK---------LTANSAILRLTKEMAWMSDEViaaekdlrkgspTTFADRVFENEINIAINQTERNYK 867
Cdd:PRK13208 564 rlGsDTPFDEKQVKigrrlltklWNASRFVLHFSADPEPDKAEV------------LEPLDRWILAKLAKVVEKATEALE 631
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 868 ALMFREALKS-------GFYD--LQIARdeYRL-----------ACSSLgmnrdlifRFA-DVQTRLLTPICPHYAEYVR 926
Cdd:PRK13208 632 NYDFAKALEEiesffwhVFCDdyLELVK--SRAygedeeeeqksARYTL--------YTVlDTLLRLLAPFLPFITEEVW 701
|
970
....*....|....*.
gi 1376981756 927 SEIFhqEGFAVTAGWP 942
Cdd:PRK13208 702 SWLY--GGSVHRASWP 715
|
|
| CysRS_core |
cd00672 |
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) ... |
723-796 |
1.61e-11 |
|
catalytic core domain of cysteinyl tRNA synthetase; Cysteinyl tRNA synthetase (CysRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173899 [Multi-domain] Cd Length: 213 Bit Score: 64.91 E-value: 1.61e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1376981756 723 FDLRVSGKDLIQNHLTFSIYNHTAMFPEeRWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGL 796
Cdd:cd00672 129 FDIHGGGVDLIFPHHENEIAQSEAATGK-PFARYWLHTGHLTIDGEKMSKSLGNFITVRDALKKYDPEVLRLAL 201
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
760-794 |
9.79e-10 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 62.43 E-value: 9.79e-10
10 20 30
....*....|....*....|....*....|....*
gi 1376981756 760 NGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRF 794
Cdd:COG0215 256 NGFLTVNGEKMSKSLGNFFTVRDLLKKYDPEVLRF 290
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
848-981 |
1.27e-09 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 57.80 E-value: 1.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 848 DRVFENEINIAINQTERNYKALMFREALKSGFYDLQIAR-DEY------RLACSSLGMN-RDLIFRFADVQTRLLTPICP 919
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLsDWYlelikdRLYGEEPDSRaQTTLYEVLETLLRLLAPFMP 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1376981756 920 HYAEYVrseifHQEGFAVTAGWPA-SGTPDLTLQRANKFFQSILADFRKA-LQKHLAASKKAKK 981
Cdd:pfam08264 81 FITEEL-----WQKESIHLAPWPEdAELEEAELEEAFELRQEIVQAIRKLrSELKIKKSLPLEV 139
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
729-876 |
1.64e-09 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 61.67 E-value: 1.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 729 GKDlIqnhltfsIYNHTAMFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADAGDS 802
Cdd:COG0143 289 GKD-I-------IRFHAIIWPamlmaaGLPLPKKVFAHGFLTVEGEKMSKSRGNVIDPDDLLDRYGPDALRYYLLREVPF 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 803 VDDANFvklTANSAILRLTKEMA-----WMS----------DEVIAAEKDLrkgsptTFADRVFENEINIAINQTERNYK 867
Cdd:COG0143 361 GQDGDF---SWEDFVARVNSDLAndlgnLASrtlsmihkyfDGKVPEPGEL------TEADEELLAEAEAALEEVAEAME 431
|
....*....
gi 1376981756 868 ALMFREALK 876
Cdd:COG0143 432 AFEFRKALE 440
|
|
| tRNA-synt_1e |
pfam01406 |
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA ... |
721-799 |
2.09e-09 |
|
tRNA synthetases class I (C) catalytic domain; This family includes only cysteinyl tRNA synthetases.
Pssm-ID: 396128 [Multi-domain] Cd Length: 301 Bit Score: 60.07 E-value: 2.09e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1376981756 721 YPFDLRVSGKDLIQNHLTFSIYNHTAMFPEErWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLADA 799
Cdd:pfam01406 206 DQIDIHGGGIDLAFPHHENEIAQSEAAFDKQ-LANYWLHNGHVMIDGEKMSKSLGNFFTIRDVLKRYDPEILRYFLLSV 283
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
572-808 |
2.34e-08 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 57.64 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 572 VISRSGDECVVALTDQWYLQYAEEewKSQAEKCLTQ--MELYSDETRRLFEHalgWLNQ---WACSRSFGLGTKFP-Wdq 645
Cdd:cd00817 155 VCSRSGDVIEPLLKPQWFVKVKDL--AKKALEAVKEgdIKFVPERMEKRYEN---WLENirdWCISRQLWWGHRIPaW-- 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 646 dfliESLSDSTIYMA---YYTLAHILQEGDLYGKGDhAVKPNQMTRNVWdFVFGMGPLPESEIPVETlkrmkKEFDYWYP 722
Cdd:cd00817 228 ----YCKDGGHWVVAreeDEAIDKAAPEACVPCGGE-ELKQDEDVLDTW-FSSSLWPFSTLGWPEET-----KDLKKFYP 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 723 FDLRVSGKDLIQNHLTFSI---YNHTAMFPeerWPRSFrCNGFLL-LNGEKMAKSTGNFLTIRDAVSDFSADATRFGLAD 798
Cdd:cd00817 297 TSLLVTGHDIIFFWVARMImrgLKLTGKLP---FKEVY-LHGLVRdEDGRKMSKSLGNVIDPLDVIDGYGADALRFTLAS 372
|
250
....*....|
gi 1376981756 799 AGDSVDDANF 808
Cdd:cd00817 373 AATQGRDINL 382
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
714-808 |
3.82e-08 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 56.91 E-value: 3.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 714 KKEFDYWYPFDLRVS-----GKDLIqnhltfsiYNHTAMFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRD 782
Cdd:pfam09334 266 EEKWKEWWPNDPDTElvhfiGKDII--------YFHTIFWPamllgaGYRLPTTVFAHGYLTYEGGKMSKSRGNVVWPSE 337
|
90 100
....*....|....*....|....*.
gi 1376981756 783 AVSDFSADATRFGLADAGDSVDDANF 808
Cdd:pfam09334 338 ALDRFPPDALRYYLARNRPETKDTDF 363
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
729-983 |
5.72e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 53.62 E-value: 5.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 729 GKDLIqnhltfsiYNHTAMFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGLA-DAGD 801
Cdd:PRK00133 291 GKDII--------YFHTLFWPamlegaGYRLPTNVFAHGFLTVEGAKMSKSRGTFIWARTYLDHLDPDYLRYYLAaKLPE 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 802 SVDD-----------------ANFVKLtANSAILRLTKEMawmsDEVIaaekdlrkgsPTTFADRVFENEINIAINQTER 864
Cdd:PRK00133 363 TIDDldfnwedfqqrvnselvGKVVNF-ASRTAGFINKRF----DGKL----------PDALADPELLEEFEAAAEKIAE 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 865 NYKALMFREALKSGfydLQIAR-----------------DEYRLA-CSSLGMNrdlIFRfadVQTRLLTPICPHYAEyvr 926
Cdd:PRK00133 428 AYEAREFRKALREI---MALADfankyvddnepwklakqDGERLQaVCSVGLN---LFR---ALAIYLKPVLPELAE--- 495
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1376981756 927 sEIFHQEGFAVTAgWPASGTPdLTLQRANKF---FQSI----LADFRKALQKHLAASKKAKKGQ 983
Cdd:PRK00133 496 -RAEAFLNLEELT-WDDAQQP-LAGHPINKFkilFTRIedkqIEALIEASKEAAAAKAAAAAAA 556
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
78-459 |
7.78e-07 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 53.62 E-value: 7.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 78 EKIIQKRWEDAKIFE--VDASDeppkpGEKYFGNFPYPYMNGVLHLGHAfsLSKLAA-----FQRLCGTKVLLPMGFHCT 150
Cdd:PLN02843 9 EPEIQKLWEENQVYKrvSDRNN-----GESFTLHDGPPYANGDLHIGHA--LNKILKdfinrYQLLQGKKVHYVPGWDCH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 151 GMPIKacadklvreseefgcppvfpTEVTDEAPAPvANKEEVPVEVKFKakkskavaksgASKYqwtimrSLGLEDDEIA 230
Cdd:PLN02843 82 GLPIE--------------------LKVLQSLDQE-ARKELTPIKLRAK-----------AAKF------AKKTVDTQRE 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 231 KFrdplywleyfppiakndlKFFGLSCDWRRSFITTEanPYYDSFvrwQFE---------HL-REKKKVGkdlryaiYSP 300
Cdd:PLN02843 124 SF------------------KRYGVWGDWENPYLTLD--PEYEAA---QIEvfgqmflngYIyRGRKPVH-------WSP 173
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 301 LDRQPCADHDRASGEG-VAPQEYVLIKM-EVQPPFTGKLKPLEgKKVFLAAATLRPETMYGQTNAWVLADGDYGAYEVSA 378
Cdd:PLN02843 174 SSRTALAEAELEYPEGhVSKSIYVAFPVvSPSETSPEELEEFL-PGLSLAIWTTTPWTMPANAAVAVNDKLQYSVVEVQS 252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 379 TEVFVVTARAALNMAYQNLSRVPQQPTCLV--------------------ELKGQDLIGLTVVSPL--AKNPVV----Yv 432
Cdd:PLN02843 253 FSEDESTSGGNKKKRPGNVLKEQQKLFLIVatdlvpaleakwgvklvvlkTFPGSDLEGCRYIHPLynRESPVViggdY- 331
|
410 420
....*....|....*....|....*..
gi 1376981756 433 lpmlnIKTDKGTGVVTSVPSDSPDDYM 459
Cdd:PLN02843 332 -----ITTESGTGLVHTAPGHGQEDYI 353
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
111-153 |
3.47e-06 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 50.71 E-value: 3.47e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1376981756 111 PYPYMNGVLHLGHAFSLS---KLAAFQRLCGTKVLLPMGFHCTGMP 153
Cdd:cd00817 8 PPPNVTGSLHMGHALNNTiqdIIARYKRMKGYNVLWPPGTDHAGIA 53
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
716-797 |
6.23e-06 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 50.27 E-value: 6.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 716 EFDYWYPFDLRVSGKDLIQNHltfSIYnhtamFP------EERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSA 789
Cdd:PRK11893 248 LFNKYWPADVHLIGKDILRFH---AVY-----WPaflmaaGLPLPKRVFAHGFLTLDGEKMSKSLGNVIDPFDLVDEYGV 319
|
....*...
gi 1376981756 790 DATRFGLA 797
Cdd:PRK11893 320 DAVRYFLL 327
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
40-153 |
6.90e-06 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 50.59 E-value: 6.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 40 SGNTGGSLRRILRCIATMASDGAEKKMSTERRDKLLGIEKIIQKRWEDAKIF----EVDASdeppKPGEKYFGNFPYPYM 115
Cdd:PLN02563 48 GGVSRSLTRRAFAAPSALTSTTAKTTPAAKRAYPFHEIEPKWQRYWEENRTFrtpdDVDTS----KPKFYVLDMFPYPSG 123
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1376981756 116 NGvLHLGHAFSLSK---LAAFQRLCGTKVLLPMGFHCTGMP 153
Cdd:PLN02563 124 AG-LHVGHPEGYTAtdiLARYKRMQGYNVLHPMGWDAFGLP 163
|
|
| PTZ00399 |
PTZ00399 |
cysteinyl-tRNA-synthetase; Provisional |
721-794 |
1.03e-05 |
|
cysteinyl-tRNA-synthetase; Provisional
Pssm-ID: 240402 [Multi-domain] Cd Length: 651 Bit Score: 49.64 E-value: 1.03e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1376981756 721 YPFDLRVSGKDLIQNHLTFSIYNHTAMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRF 794
Cdd:PTZ00399 267 DPIDIHSGGIDLKFPHHDNELAQSEAYFDKHQWVNYFLHSGHLHIKGLKMSKSLKNFITIRQALSKYTARQIRL 340
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
111-168 |
6.08e-04 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 43.29 E-value: 6.08e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1376981756 111 PYPYMNGVLHLGHAFS--LSK-LAAFQRLCGTKVLLPMGFHCTGMPIKACADKLVRESEEF 168
Cdd:cd00814 7 ALPYVNGVPHLGHLYGtvLADvFARYQRLRGYDVLFVTGTDEHGTKIEQKAEEEGVTPQEL 67
|
|
| cysS |
PRK14535 |
cysteinyl-tRNA synthetase; Provisional |
760-794 |
6.88e-04 |
|
cysteinyl-tRNA synthetase; Provisional
Pssm-ID: 173001 [Multi-domain] Cd Length: 699 Bit Score: 43.94 E-value: 6.88e-04
10 20 30
....*....|....*....|....*....|....*
gi 1376981756 760 NGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRF 794
Cdd:PRK14535 499 NGFIRVDGEKMSKSLGNFFTIREVLKQYDPEVVRF 533
|
|
| PLN02946 |
PLN02946 |
cysteine-tRNA ligase |
721-796 |
7.50e-04 |
|
cysteine-tRNA ligase
Pssm-ID: 178532 [Multi-domain] Cd Length: 557 Bit Score: 43.38 E-value: 7.50e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1376981756 721 YPFDLRVSGKDLIQNHLTFSIYNHTAMFPEER---WPRsfrcNGFLLLNGEKMAKSTGNFLTIRDAVSDFSADATRFGL 796
Cdd:PLN02946 276 HSFDIHGGGMDLVFPHHENEIAQSCAACCDSNisyWIH----NGFVTVDSEKMSKSLGNFFTIRQVIDLYHPLALRLFL 350
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
77-124 |
1.06e-03 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 43.15 E-value: 1.06e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1376981756 77 IEKIIQKRWEDAKIFEvdASDEPPKPGEKYF---GnfPyPYMNGVLHLGHA 124
Cdd:COG0060 21 REPEILKFWEENDIYE--KSREARAGRPKFVlhdG--P-PYANGDIHIGHA 66
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
711-860 |
2.22e-03 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 42.01 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 711 KRMKKEFDYWYPFDLRVSGKDLIQNHLTFsiYNHTAMFPEERWPRSFRCNGFLLLNGEKMAKSTGNFLTIRDAVSDFSAD 790
Cdd:PLN02224 310 QNLETAVSFGWPASLHLIGKDILRFHAVY--WPAMLMSAGLELPKMVFGHGFLTKDGMKMGKSLGNTLEPFELVQKFGPD 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1376981756 791 ATRF------GLADAGDSVDDaNFVKLT----ANS---------AILRLTKEMAWMSDEVIAAEKDLRKGSPTTFADRVF 851
Cdd:PLN02224 388 AVRYfflrevEFGNDGDYSED-RFIKIVnahlANTignllnrtlGLLKKNCESTLVEDSTVAAEGVPLKDTVEKLVEKAQ 466
|
....*....
gi 1376981756 852 ENEINIAIN 860
Cdd:PLN02224 467 TNYENLSLS 475
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
77-125 |
7.14e-03 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 40.47 E-value: 7.14e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1376981756 77 IEKIIQKRWEDAKIFEVDASDEPPkpgekyfgnF----PYPYMNGVLHLGHAF 125
Cdd:PRK05729 14 VEAKWYQKWEEKGYFKPDDNSKKP---------FsiviPPPNVTGSLHMGHAL 57
|
|
| |
