|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02894 |
PLN02894 |
hydrolase, alpha/beta fold family protein |
1-428 |
0e+00 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 215484 [Multi-domain] Cd Length: 402 Bit Score: 566.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 1 MKVQLRGHEIPGHGKSSPNKAPAARLPETTRTTGLTHRPRSWGRGWSPCLLHPAQQLarpchgrLKLDASPNSHPLVDQI 80
Cdd:PLN02894 1 MKVQLRGHEIPGHGAASSAAASAAASAETSRTRSLWPSPLRWIPTSTDHIIAAEKRL-------LSLVKTPYVQEQVNIG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 81 H--PVAADLLTRGQGGGAP--GAASLPGDRVDPPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSGRPPYRAR 156
Cdd:PLN02894 74 SgpPGSKVRWFRSASNEPRfiNTVTFDSKEDAPTLVMVHGYGASQGFFFRNFDALASRFRVIAIDQLGWGGSSRPDFTCK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 157 TREQAEDFFLTSLAEWRRAAGLEGSKMvlvgldvpgiqggVGHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPEDWE 236
Cdd:PLN02894 154 STEETEAWFIDSFEEWRKAKNLSNFIL-------------LGHSFGGYVAAKYALKHPEHVQHLILVGPAGFSSESDDKS 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 237 RRWLGDKWSWRGQMFKMFmwgWEKGVTPGAIIRGLGPWGQNLVFKYVANRFSHHGEG--LSQREIDLFKEYFYSIAALPG 314
Cdd:PLN02894 221 EWLTKFRATWKGAVLNHL---WESNFTPQKIIRGLGPWGPNLVRRYTTARFGAHSTGdiLSEEESKLLTDYVYHTLAAKA 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 315 SGEYALRHLLAPGAWAHAPLEERLHELKVPVTFIYGRHDWMRPEYAVQLCARLrkERPPSapndltVEIIDDAGHFVFLD 394
Cdd:PLN02894 298 SGELCLKYIFSFGAFARKPLLESASEWKVPTTFIYGRHDWMNYEGAVEARKRM--KVPCE------IIRVPQGGHFVFLD 369
|
410 420 430
....*....|....*....|....*....|....
gi 302844406 395 QPELFDKALTNVVLPYLRTARQReRAAAYVTAGT 428
Cdd:PLN02894 370 NPSGFHSAVLYACRKYLSPDREE-RALPEGLTSA 402
|
|
| MenH |
COG0596 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ... |
109-403 |
5.95e-25 |
|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440361 [Multi-domain] Cd Length: 221 Bit Score: 102.39 E-value: 5.95e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 109 PPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSGRPPYRARTREQAEDffltsLAEWRRAAGLEgsKMVLVGl 188
Cdd:COG0596 24 PPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADD-----LAALLDALGLE--RVVLVG- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 189 dvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLVCPAgvpkapedwerrwlgdkwswrgqmfkmfmwgwekgvtpgaii 268
Cdd:COG0596 96 ----------HSMGGMVALELAARHPERVAGLVLVDEV------------------------------------------ 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 269 rglgpwgqnlvfkyvanrfshhgeglsqreIDLFKEYFysiaALPGSGEYALRHLLApgAWAHAPLEERLHELKVPVTFI 348
Cdd:COG0596 124 ------------------------------LAALAEPL----RRPGLAPEALAALLR--ALARTDLRERLARITVPTLVI 167
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 302844406 349 YGRHDWMRPeyaVQLCARLRKERPpsapnDLTVEIIDDAGHFVFLDQPELFDKAL 403
Cdd:COG0596 168 WGEKDPIVP---PALARRLAELLP-----NAELVVLPGAGHFPPLEQPEAFAAAL 214
|
|
| Abhydrolase_1 |
pfam00561 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
109-396 |
4.73e-24 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 395444 [Multi-domain] Cd Length: 245 Bit Score: 100.66 E-value: 4.73e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 109 PPVVMMPGYGAGVGFYYRNFPSLAR-QLRLFAVDWLGTGLSGRPPYRARTREqaeDFFLTSLAEWRRAAGLEgsKMVLVG 187
Cdd:pfam00561 1 PPVLLLHGLPGSSDLWRKLAPALARdGFRVIALDLRGFGKSSRPKAQDDYRT---DDLAEDLEYILEALGLE--KVNLVG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 188 ldvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPEDWERRWLGDK-WSWRGQMFKmfmwgwekgvtpgA 266
Cdd:pfam00561 76 -----------HSMGGLIALAYAAKYPDRVKALVLLGALDPPHELDEADRFILALFpGFFDGFVAD-------------F 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 267 IIRGLGPWGQNLVFKYvanRFSHHGEGLSQREIDLFKEYFYSIAALPGSGeyalrHLLAPGAWAHAPLEERLHELKVPVT 346
Cdd:pfam00561 132 APNPLGRLVAKLLALL---LLRLRLLKALPLLNKRFPSGDYALAKSLVTG-----ALLFIETWSTELRAKFLGRLDEPTL 203
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 302844406 347 FIYGRHDWMRPEYAVQLCARLrkerppsaPNDLTVEIIDDAGHFVFLDQP 396
Cdd:pfam00561 204 IIWGDQDPLVPPQALEKLAQL--------FPNARLVVIPDAGHFAFLEGP 245
|
|
| pro_imino_pep_2 |
TIGR01250 |
proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a ... |
108-412 |
4.27e-09 |
|
proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase
Pssm-ID: 188121 [Multi-domain] Cd Length: 289 Bit Score: 57.39 E-value: 4.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 108 DPPVVMMPGYGAGVGFYYRNFPSLARQL--RLFAVDWLGTGLSGRPPYrarTREQ--AEDFFLTSLAEWRRAAGLEgsKM 183
Cdd:TIGR01250 25 KIKLLLLHGGPGMSHEYLENLRELLKEEgrEVIMYDQLGCGYSDQPDD---SDEElwTIDYFVDELEEVREKLGLD--KF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 184 VLVGldvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLvcPAGVPKAPEdwerrwlgdkwswrgqmfkmfmwgWEKGVT 263
Cdd:TIGR01250 100 YLLG-----------HSWGGMLAQEYALKYGQHLKGLII--SSMLDSAPE------------------------YVKELN 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 264 pgAIIRGLGPWGQNLVFKYVANRFSHHGEglSQREIDLF-KEYFYSIAALPGsgeyALRHLLAPGA-----WAHAPLE-- 335
Cdd:TIGR01250 143 --RLRKELPPEVRAAIKRCEASGDYDNPE--YQEAVEVFyHHLLCRLRKWPE----ALKHLKSGGNtnvynIMQGPNEft 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 336 -----------ERLHELKVPVTFIYGRHDWMRPEYAVQLCARLRKERppsapndltVEIIDDAGHFVFLDQPELFDKalt 404
Cdd:TIGR01250 215 itgnlkdwditDKLSEIKVPTLLTVGEFDTMTPEAAREMQELIAGSR---------LVVFPDGSHMTMIEDPEVYFK--- 282
|
....*...
gi 302844406 405 nVVLPYLR 412
Cdd:TIGR01250 283 -LLSDFIR 289
|
|
| Esterase_713_like-1 |
cd12808 |
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
197-234 |
5.18e-04 |
|
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown.
Pssm-ID: 214007 Cd Length: 309 Bit Score: 41.85 E-value: 5.18e-04
10 20 30
....*....|....*....|....*....|....*...
gi 302844406 197 VGHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPED 234
Cdd:cd12808 193 VAHSQGGGFAFEAARARPDLVRAVVALEPSGAPDPAEA 230
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02894 |
PLN02894 |
hydrolase, alpha/beta fold family protein |
1-428 |
0e+00 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 215484 [Multi-domain] Cd Length: 402 Bit Score: 566.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 1 MKVQLRGHEIPGHGKSSPNKAPAARLPETTRTTGLTHRPRSWGRGWSPCLLHPAQQLarpchgrLKLDASPNSHPLVDQI 80
Cdd:PLN02894 1 MKVQLRGHEIPGHGAASSAAASAAASAETSRTRSLWPSPLRWIPTSTDHIIAAEKRL-------LSLVKTPYVQEQVNIG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 81 H--PVAADLLTRGQGGGAP--GAASLPGDRVDPPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSGRPPYRAR 156
Cdd:PLN02894 74 SgpPGSKVRWFRSASNEPRfiNTVTFDSKEDAPTLVMVHGYGASQGFFFRNFDALASRFRVIAIDQLGWGGSSRPDFTCK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 157 TREQAEDFFLTSLAEWRRAAGLEGSKMvlvgldvpgiqggVGHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPEDWE 236
Cdd:PLN02894 154 STEETEAWFIDSFEEWRKAKNLSNFIL-------------LGHSFGGYVAAKYALKHPEHVQHLILVGPAGFSSESDDKS 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 237 RRWLGDKWSWRGQMFKMFmwgWEKGVTPGAIIRGLGPWGQNLVFKYVANRFSHHGEG--LSQREIDLFKEYFYSIAALPG 314
Cdd:PLN02894 221 EWLTKFRATWKGAVLNHL---WESNFTPQKIIRGLGPWGPNLVRRYTTARFGAHSTGdiLSEEESKLLTDYVYHTLAAKA 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 315 SGEYALRHLLAPGAWAHAPLEERLHELKVPVTFIYGRHDWMRPEYAVQLCARLrkERPPSapndltVEIIDDAGHFVFLD 394
Cdd:PLN02894 298 SGELCLKYIFSFGAFARKPLLESASEWKVPTTFIYGRHDWMNYEGAVEARKRM--KVPCE------IIRVPQGGHFVFLD 369
|
410 420 430
....*....|....*....|....*....|....
gi 302844406 395 QPELFDKALTNVVLPYLRTARQReRAAAYVTAGT 428
Cdd:PLN02894 370 NPSGFHSAVLYACRKYLSPDREE-RALPEGLTSA 402
|
|
| MenH |
COG0596 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ... |
109-403 |
5.95e-25 |
|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440361 [Multi-domain] Cd Length: 221 Bit Score: 102.39 E-value: 5.95e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 109 PPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSGRPPYRARTREQAEDffltsLAEWRRAAGLEgsKMVLVGl 188
Cdd:COG0596 24 PPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDDLADD-----LAALLDALGLE--RVVLVG- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 189 dvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLVCPAgvpkapedwerrwlgdkwswrgqmfkmfmwgwekgvtpgaii 268
Cdd:COG0596 96 ----------HSMGGMVALELAARHPERVAGLVLVDEV------------------------------------------ 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 269 rglgpwgqnlvfkyvanrfshhgeglsqreIDLFKEYFysiaALPGSGEYALRHLLApgAWAHAPLEERLHELKVPVTFI 348
Cdd:COG0596 124 ------------------------------LAALAEPL----RRPGLAPEALAALLR--ALARTDLRERLARITVPTLVI 167
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 302844406 349 YGRHDWMRPeyaVQLCARLRKERPpsapnDLTVEIIDDAGHFVFLDQPELFDKAL 403
Cdd:COG0596 168 WGEKDPIVP---PALARRLAELLP-----NAELVVLPGAGHFPPLEQPEAFAAAL 214
|
|
| Abhydrolase_1 |
pfam00561 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
109-396 |
4.73e-24 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 395444 [Multi-domain] Cd Length: 245 Bit Score: 100.66 E-value: 4.73e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 109 PPVVMMPGYGAGVGFYYRNFPSLAR-QLRLFAVDWLGTGLSGRPPYRARTREqaeDFFLTSLAEWRRAAGLEgsKMVLVG 187
Cdd:pfam00561 1 PPVLLLHGLPGSSDLWRKLAPALARdGFRVIALDLRGFGKSSRPKAQDDYRT---DDLAEDLEYILEALGLE--KVNLVG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 188 ldvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPEDWERRWLGDK-WSWRGQMFKmfmwgwekgvtpgA 266
Cdd:pfam00561 76 -----------HSMGGLIALAYAAKYPDRVKALVLLGALDPPHELDEADRFILALFpGFFDGFVAD-------------F 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 267 IIRGLGPWGQNLVFKYvanRFSHHGEGLSQREIDLFKEYFYSIAALPGSGeyalrHLLAPGAWAHAPLEERLHELKVPVT 346
Cdd:pfam00561 132 APNPLGRLVAKLLALL---LLRLRLLKALPLLNKRFPSGDYALAKSLVTG-----ALLFIETWSTELRAKFLGRLDEPTL 203
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 302844406 347 FIYGRHDWMRPEYAVQLCARLrkerppsaPNDLTVEIIDDAGHFVFLDQP 396
Cdd:pfam00561 204 IIWGDQDPLVPPQALEKLAQL--------FPNARLVVIPDAGHFAFLEGP 245
|
|
| PldB |
COG2267 |
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism]; |
102-242 |
1.35e-13 |
|
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
Pssm-ID: 441868 [Multi-domain] Cd Length: 221 Bit Score: 70.03 E-value: 1.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 102 LPGDRVDPPVVMMPGYGAGVGFYYRNFPSLARQ-LRLFAVDWLGTGLSGRPP-YRARTREQAEDFfltsLAEWRRAAGLE 179
Cdd:COG2267 22 RPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAgYAVLAFDLRGHGRSDGPRgHVDSFDDYVDDL----RAALDALRARP 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 302844406 180 GSKMVLVGldvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPEDWERRWLGD 242
Cdd:COG2267 98 GLPVVLLG-----------HSMGGLIALLYAARYPDRVAGLVLLAPAYRADPLLGPSARWLRA 149
|
|
| PRK14875 |
PRK14875 |
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional |
104-403 |
8.12e-11 |
|
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
Pssm-ID: 184875 [Multi-domain] Cd Length: 371 Bit Score: 63.42 E-value: 8.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 104 GDRVDPPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSgrppyrarTREQAEdfflTSLAEWrraaglegSKM 183
Cdd:PRK14875 127 GEGDGTPVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGHGAS--------SKAVGA----GSLDEL--------AAA 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 184 VLVGLDVPGIQGG--VGHSLGGYLAANYALRYPEHVQHLVLVCPAGvpkapedwerrwLGDKWSwrgqmfkmfmWGWEKG 261
Cdd:PRK14875 187 VLAFLDALGIERAhlVGHSMGGAVALRLAARAPQRVASLTLIAPAG------------LGPEIN----------GDYIDG 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 262 VTPGAIIRGLGPWGQNLVfkyvanrfsHHGEGLSQREI-DLFKEyfysiAALPGSGEyALRHL---LAPGAWAHAPLEER 337
Cdd:PRK14875 245 FVAAESRRELKPVLELLF---------ADPALVTRQMVeDLLKY-----KRLDGVDD-ALRALadaLFAGGRQRVDLRDR 309
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 302844406 338 LHELKVPVTFIYGRHDWMRP-EYAVQLcarlrkerppsaPNDLTVEIIDDAGHFVFLDQPELFDKAL 403
Cdd:PRK14875 310 LASLAIPVLVIWGEQDRIIPaAHAQGL------------PDGVAVHVLPGAGHMPQMEAAADVNRLL 364
|
|
| pro_imino_pep_2 |
TIGR01250 |
proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a ... |
108-412 |
4.27e-09 |
|
proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase
Pssm-ID: 188121 [Multi-domain] Cd Length: 289 Bit Score: 57.39 E-value: 4.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 108 DPPVVMMPGYGAGVGFYYRNFPSLARQL--RLFAVDWLGTGLSGRPPYrarTREQ--AEDFFLTSLAEWRRAAGLEgsKM 183
Cdd:TIGR01250 25 KIKLLLLHGGPGMSHEYLENLRELLKEEgrEVIMYDQLGCGYSDQPDD---SDEElwTIDYFVDELEEVREKLGLD--KF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 184 VLVGldvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLvcPAGVPKAPEdwerrwlgdkwswrgqmfkmfmwgWEKGVT 263
Cdd:TIGR01250 100 YLLG-----------HSWGGMLAQEYALKYGQHLKGLII--SSMLDSAPE------------------------YVKELN 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 264 pgAIIRGLGPWGQNLVFKYVANRFSHHGEglSQREIDLF-KEYFYSIAALPGsgeyALRHLLAPGA-----WAHAPLE-- 335
Cdd:TIGR01250 143 --RLRKELPPEVRAAIKRCEASGDYDNPE--YQEAVEVFyHHLLCRLRKWPE----ALKHLKSGGNtnvynIMQGPNEft 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 336 -----------ERLHELKVPVTFIYGRHDWMRPEYAVQLCARLRKERppsapndltVEIIDDAGHFVFLDQPELFDKalt 404
Cdd:TIGR01250 215 itgnlkdwditDKLSEIKVPTLLTVGEFDTMTPEAAREMQELIAGSR---------LVVFPDGSHMTMIEDPEVYFK--- 282
|
....*...
gi 302844406 405 nVVLPYLR 412
Cdd:TIGR01250 283 -LLSDFIR 289
|
|
| YvaK |
COG1647 |
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism]; |
162-404 |
7.02e-09 |
|
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 441253 [Multi-domain] Cd Length: 246 Bit Score: 56.49 E-value: 7.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 162 EDFFLTSLAEWRRAA------GLEGSKMVLVgldvpgiqggVGHSLGGYLAANYALRYPEhVQHLVLVCPAgvpkapedw 235
Cdd:COG1647 58 EDLLKTTWEDWLEDVeeayeiLKAGYDKVIV----------IGLSMGGLLALLLAARYPD-VAGLVLLSPA--------- 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 236 errwlgdkwswrgqmfkMFMWGWEKGVTPgaiirglgpwgqnlVFKYVANRFSHHGeglsqREIDLFKEYFYSIAALPGS 315
Cdd:COG1647 118 -----------------LKIDDPSAPLLP--------------LLKYLARSLRGIG-----SDIEDPEVAEYAYDRTPLR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 316 GEYALRHLLapgawahAPLEERLHELKVPVTFIYGRHDWM-RPEYAVQLCARLrkerpPSAPNDLTVeiIDDAGHFVFLD 394
Cdd:COG1647 162 ALAELQRLI-------REVRRDLPKITAPTLIIQSRKDEVvPPESARYIYERL-----GSPDKELVW--LEDSGHVITLD 227
|
250
....*....|..
gi 302844406 395 --QPELFDKALT 404
Cdd:COG1647 228 kdREEVAEEILD 239
|
|
| PLN02578 |
PLN02578 |
hydrolase |
109-227 |
1.70e-08 |
|
hydrolase
Pssm-ID: 215315 [Multi-domain] Cd Length: 354 Bit Score: 56.39 E-value: 1.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 109 PPVVMMPGYGAGVgFYYR-NFPSLARQLRLFAVDWLGTGLSGRP--PYRART-REQAEDFFLTSLAEwrraaglegskmv 184
Cdd:PLN02578 87 LPIVLIHGFGASA-FHWRyNIPELAKKYKVYALDLLGFGWSDKAliEYDAMVwRDQVADFVKEVVKE------------- 152
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 302844406 185 lvgldvPGIQggVGHSLGGYLAANYALRYPEHVQHLVLVCPAG 227
Cdd:PLN02578 153 ------PAVL--VGNSLGGFTALSTAVGYPELVAGVALLNSAG 187
|
|
| Hydrolase_4 |
pfam12146 |
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ... |
111-232 |
2.22e-06 |
|
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.
Pssm-ID: 463473 [Multi-domain] Cd Length: 238 Bit Score: 48.75 E-value: 2.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 111 VVMMPGYGAGVGFYYRNFPSLARQ-LRLFAVDWLGTGLSGRppyrARTREQAEDFFLTSLAEWRRAAGLE--GSKMVLVG 187
Cdd:pfam12146 7 VVLVHGLGEHSGRYAHLADALAAQgFAVYAYDHRGHGRSDG----KRGHVPSFDDYVDDLDTFVDKIREEhpGLPLFLLG 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 302844406 188 ldvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAP 232
Cdd:pfam12146 83 -----------HSMGGLIAALYALRYPDKVDGLILSAPALKIKPY 116
|
|
| PLN02679 |
PLN02679 |
hydrolase, alpha/beta fold family protein |
108-227 |
1.84e-05 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 178283 [Multi-domain] Cd Length: 360 Bit Score: 46.76 E-value: 1.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 108 DPPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSGRPPYRARTREQAEDFFLTSLAEwrraagLEGSKMVLVG 187
Cdd:PLN02679 88 GPPVLLVHGFGASIPHWRRNIGVLAKNYTVYAIDLLGFGASDKPPGFSYTMETWAELILDFLEE------VVQKPTVLIG 161
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 302844406 188 ldvpgiqGGVGhSLGGYLAANYALRypEHVQHLVLVCPAG 227
Cdd:PLN02679 162 -------NSVG-SLACVIAASESTR--DLVRGLVLLNCAG 191
|
|
| Abhydrolase_6 |
pfam12697 |
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ... |
111-248 |
2.54e-05 |
|
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.
Pssm-ID: 463673 [Multi-domain] Cd Length: 211 Bit Score: 45.16 E-value: 2.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 111 VVMMPGYGAGVGFYyrnFPSLARQLRLFAVDWLGTGLSGRPPYRARTREQAEDfFLTSLAEWRRAAglegskmvlvgldv 190
Cdd:pfam12697 1 VVLVHGAGLSAAPL---AALLAAGVAVLAPDLPGHGSSSPPPLDLADLADLAA-LLDELGAARPVV-------------- 62
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 302844406 191 pgiqgGVGHSLGGYLAANYALRYPEHVqhlVLVCPAGVPKAPEDWERRWLGDKWSWRG 248
Cdd:pfam12697 63 -----LVGHSLGGAVALAAAAAALVVG---VLVAPLAAPPGLLAALLALLARLGAALA 112
|
|
| EstA |
COG1075 |
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ... |
110-225 |
1.17e-04 |
|
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];
Pssm-ID: 440693 [Multi-domain] Cd Length: 106 Bit Score: 41.35 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 110 PVVMMPGYGAGVGFYYRNFPSLARQ-LRLFAVDWlgtglsgrPPYRARTREQAEDFfLTSLAEWRRAAGleGSKMVLVGl 188
Cdd:COG1075 7 PVVLVHGLGGSAASWAPLAPRLRAAgYPVYALNY--------PSTNGSIEDSAEQL-AAFVDAVLAATG--AEKVDLVG- 74
|
90 100 110
....*....|....*....|....*....|....*....
gi 302844406 189 dvpgiqggvgHSLGGYLAANYA--LRYPEHVQHLVLVCP 225
Cdd:COG1075 75 ----------HSMGGLVARYYLkrLGGAAKVARVVTLGT 103
|
|
| PLN02824 |
PLN02824 |
hydrolase, alpha/beta fold family protein |
109-164 |
2.26e-04 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 178419 [Multi-domain] Cd Length: 294 Bit Score: 43.19 E-value: 2.26e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302844406 109 PPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSGRPPYRARTR----------EQAEDF 164
Cdd:PLN02824 30 PALVLVHGFGGNADHWRKNTPVLAKSHRVYAIDLLGYGYSDKPNPRSAPPnsfytfetwgEQLNDF 95
|
|
| bioH |
TIGR01738 |
pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for ... |
109-403 |
2.93e-04 |
|
pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]
Pssm-ID: 273783 [Multi-domain] Cd Length: 245 Bit Score: 42.50 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 109 PPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSgrppyrartreqaedffltslAEWRRAAGLEGSKMVLVGL 188
Cdd:TIGR01738 5 VHLVLIHGWGMNAEVFRCLDEELSAHFTLHLVDLPGHGRS---------------------RGFGPLSLADMAEAIAAQA 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 189 DVPGIQggVGHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPEDwerrwlgdkwswrgqmfkmfmwgWEKGVTPGAII 268
Cdd:TIGR01738 64 PDPAIW--LGWSLGGLVALHIAATHPDRVRALVTVASSPCFSARED-----------------------WPEGIKPDVLT 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 269 RGLGPWGQNlvFKYVANRF---SHHGEGLSQREIDLFKEyfySIAALPGSGEYALRHLLApgAWAHAPLEERLHELKVPV 345
Cdd:TIGR01738 119 GFQQQLSDD--YQRTIERFlalQTLGTPTARQDARALKQ---TLLARPTPNVQVLQAGLE--ILATVDLRQPLQNISVPF 191
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 302844406 346 TFIYGRHDWMRPEYAVQLCARLrkerppsAPNDLTVeIIDDAGHFVFLDQPELFDKAL 403
Cdd:TIGR01738 192 LRLYGYLDGLVPAKVVPMLDKL-------APHSELY-IFAKAAHAPFLSHAEAFCALL 241
|
|
| Esterase_713_like-1 |
cd12808 |
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
197-234 |
5.18e-04 |
|
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown.
Pssm-ID: 214007 Cd Length: 309 Bit Score: 41.85 E-value: 5.18e-04
10 20 30
....*....|....*....|....*....|....*...
gi 302844406 197 VGHSLGGYLAANYALRYPEHVQHLVLVCPAGVPKAPED 234
Cdd:cd12808 193 VAHSQGGGFAFEAARARPDLVRAVVALEPSGAPDPAEA 230
|
|
| PRK03592 |
PRK03592 |
haloalkane dehalogenase; Provisional |
125-273 |
6.55e-04 |
|
haloalkane dehalogenase; Provisional
Pssm-ID: 235135 Cd Length: 295 Bit Score: 41.52 E-value: 6.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 125 YRN-FPSLARQLRLFAVDWLGTGLSGRPPYRARTREQAeDFfltsLAEWRRAAGLEGskMVLVGldvpgiqggvgHSLGG 203
Cdd:PRK03592 43 WRNiIPHLAGLGRCLAPDLIGMGASDKPDIDYTFADHA-RY----LDAWFDALGLDD--VVLVG-----------HDWGS 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 302844406 204 YLAANYALRYPEHVQHLVLVCPAGVPKAPEDWERRWLGdkwswRGQMFKMFMWGWEK---------GVTPGAIIRGLGP 273
Cdd:PRK03592 105 ALGFDWAARHPDRVRGIAFMEAIVRPMTWDDFPPAVRE-----LFQALRSPGEGEEMvleenvfieRVLPGSILRPLSD 178
|
|
| PLN03084 |
PLN03084 |
alpha/beta hydrolase fold protein; Provisional |
104-245 |
1.58e-03 |
|
alpha/beta hydrolase fold protein; Provisional
Pssm-ID: 178633 Cd Length: 383 Bit Score: 40.63 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 104 GDRVDPPVVMMPGYGAGVGFYYRNFPSLARQLRLFAVDWLGTGLSGRPpyrartreQAEDFFLTSLAEWRRAAG-----L 178
Cdd:PLN03084 123 GSNNNPPVLLIHGFPSQAYSYRKVLPVLSKNYHAIAFDWLGFGFSDKP--------QPGYGFNYTLDEYVSSLEslideL 194
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 302844406 179 EGSKMVLVgldvpgIQggvghslgGYLAA---NYALRYPEHVQHLVLVCP------AGVPKAPEDWERRWLGDKWS 245
Cdd:PLN03084 195 KSDKVSLV------VQ--------GYFSPpvvKYASAHPDKIKKLILLNPpltkehAKLPSTLSEFSNFLLGEIFS 256
|
|
| YpfH |
COG0400 |
Predicted esterase [General function prediction only]; |
104-238 |
2.69e-03 |
|
Predicted esterase [General function prediction only];
Pssm-ID: 440169 [Multi-domain] Cd Length: 200 Bit Score: 39.12 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 104 GDRVDPPVVMMPGYGAGVgfyyRNFPSLARQLRLFAVDWL---GTGLSGRPPYR------ARTREQAEDF------FLTS 168
Cdd:COG0400 1 GGPAAPLVVLLHGYGGDE----EDLLPLAPELALPGAAVLaprAPVPEGPGGRAwfdlsfLEGREDEEGLaaaaeaLAAF 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 169 LAEWRRAAGLEGSKMVLVGldvpgiqggvgHSLGGYLAANYALRYPEHVQHLVLVCPaGVPKAPEDWERR 238
Cdd:COG0400 77 IDELEARYGIDPERIVLAG-----------FSQGAAMALSLALRRPELLAGVVALSG-YLPGEEALPAPE 134
|
|
| COG4757 |
COG4757 |
Predicted alpha/beta hydrolase [General function prediction only]; |
103-404 |
7.17e-03 |
|
Predicted alpha/beta hydrolase [General function prediction only];
Pssm-ID: 443790 [Multi-domain] Cd Length: 289 Bit Score: 38.33 E-value: 7.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 103 PGDRVDPPVVMMPGYGAGVGFYYRnfpsLARQL--RLFAV---DWLGTGLSGRPPYRARTreqaedfflTSLAEW----- 172
Cdd:COG4757 27 PAGPPRAVVLINPATGVPQRFYRP----FARYLaeRGFAVltyDYRGIGLSRPGSLRGFD---------AGYRDWgeldl 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 173 ----RRAAGLEGSKMVLVgldvpgiqggVGHSLGGYLAANYAlrYPEHVQHLVLVCpAGVPkapedWERRWlgdKWSWRG 248
Cdd:COG4757 94 pavlDALRARFPGLPLLL----------VGHSLGGQLLGLAP--NAERVDRLVTVA-SGSG-----YWRDY---PPRRRL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 249 QMFkmFMWGW-------EKGVTPGaiiRGLGpWGQNLvFKYVANRFSHHGeglsqreidLFKEYFYSiaalpgsgeyalr 321
Cdd:COG4757 153 KVL--LFWHLlgplltrLLGYFPG---RRLG-FGEDL-PAGVARQWRRWC---------RRPRYFFD------------- 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 302844406 322 hllAPGAWahapLEERLHELKVPVTFIYGRHDWMRPEYAVQ-LCARLRKERPPS---APNDLTVEiidDAGHFVFL---D 394
Cdd:COG4757 204 ---DDGED----LEAALAAVTAPVLAISFTDDELAPPAAVDrLLAYYPNAPVTRrrlAPADLGLK---RIGHFGFFrrrF 273
|
330
....*....|
gi 302844406 395 QPELFDKALT 404
Cdd:COG4757 274 AAALWPRVLD 283
|
|
| |
