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Conserved domains on  [gi|167516060|ref|XP_001742371|]
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uncharacterized protein MONBRDRAFT_13706, partial [Monosiga brevicollis MX1]

Protein Classification

zinc finger CCCH domain-containing protein( domain architecture ID 708395)

zinc finger CCCH domain-containing protein similar to cleavage and polyadenylation specificity factor (CPSF) subunit 4, which is part of the complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YTH1 super family cl25862
Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin ...
 109-190 1.13e-07

Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only];


The actual alignment was detected with superfamily member COG5084:

Pssm-ID: 227416 [Multi-domain]  Cd Length: 285  Bit Score: 50.64  E-value: 1.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167516060 109 PEERLRTVPCQFHQHGR-CQKGEACPFSHAEPQVHKQDLCKFFLSNDCKKGDACLYSHDPSL-----FPCRFYHT-GGCD 181
Cdd:COG5084   68 NFVPGNTVACISRNFNSiRGSRLSTPNNHVNPVLSSSVVCKFFLRGLCKSGFSCEFLHEYDLrssqgPPCRSFSLkGSCS 147

                         90
                 ....*....|
gi 167516060 182 RT-DCRFSHE 190
Cdd:COG5084  148 SGpSCGYSHI 157
 
Name Accession Description Interval E-value
YTH1 COG5084
Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin ...
 109-190 1.13e-07

Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only];


Pssm-ID: 227416 [Multi-domain]  Cd Length: 285  Bit Score: 50.64  E-value: 1.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167516060 109 PEERLRTVPCQFHQHGR-CQKGEACPFSHAEPQVHKQDLCKFFLSNDCKKGDACLYSHDPSL-----FPCRFYHT-GGCD 181
Cdd:COG5084   68 NFVPGNTVACISRNFNSiRGSRLSTPNNHVNPVLSSSVVCKFFLRGLCKSGFSCEFLHEYDLrssqgPPCRSFSLkGSCS 147

                         90
                 ....*....|
gi 167516060 182 RT-DCRFSHE 190
Cdd:COG5084  148 SGpSCGYSHI 157
zf-CCCH_3 pfam15663
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
 142-189 9.56e-05

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 40.14  E-value: 9.56e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 167516060  142 HKQDLCKFFLSNDCKKGDACLYSHDPSLFP----CRFYHTGGCDRTDCRFSH 189
Cdd:pfam15663   3 NKGDDCYFFYYSTCTKGDSCPFRHCEAALGnetvCTLWQEGRCFRPVCRFRH 54
ZnF_C3H1 smart00356
zinc finger;
112-136 3.00e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 34.14  E-value: 3.00e-03
                           10        20
                   ....*....|....*....|....*
gi 167516060   112 RLRTVPCQFHQHGRCQKGEACPFSH 136
Cdd:smart00356   1 KYKTELCKFFKRGYCPRGDRCKFAH 25
 
Name Accession Description Interval E-value
YTH1 COG5084
Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin ...
 109-190 1.13e-07

Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only];


Pssm-ID: 227416 [Multi-domain]  Cd Length: 285  Bit Score: 50.64  E-value: 1.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167516060 109 PEERLRTVPCQFHQHGR-CQKGEACPFSHAEPQVHKQDLCKFFLSNDCKKGDACLYSHDPSL-----FPCRFYHT-GGCD 181
Cdd:COG5084   68 NFVPGNTVACISRNFNSiRGSRLSTPNNHVNPVLSSSVVCKFFLRGLCKSGFSCEFLHEYDLrssqgPPCRSFSLkGSCS 147

                         90
                 ....*....|
gi 167516060 182 RT-DCRFSHE 190
Cdd:COG5084  148 SGpSCGYSHI 157
zf-CCCH_3 pfam15663
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
 142-189 9.56e-05

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 40.14  E-value: 9.56e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 167516060  142 HKQDLCKFFLSNDCKKGDACLYSHDPSLFP----CRFYHTGGCDRTDCRFSH 189
Cdd:pfam15663   3 NKGDDCYFFYYSTCTKGDSCPFRHCEAALGnetvCTLWQEGRCFRPVCRFRH 54
ZnF_C3H1 smart00356
zinc finger;
112-136 3.00e-03

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 34.14  E-value: 3.00e-03
                           10        20
                   ....*....|....*....|....*
gi 167516060   112 RLRTVPCQFHQHGRCQKGEACPFSH 136
Cdd:smart00356   1 KYKTELCKFFKRGYCPRGDRCKFAH 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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