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Conserved domains on  [gi|2752359667|gb|XCG20900|]
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ADP-ribosylarginine hydrolase Tri1 [Enterobacter hormaechei]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ADPriboarghdlase super family cl46019
ADP-ribosylarginine hydrolase Tri1;
1-362 0e+00

ADP-ribosylarginine hydrolase Tri1;


The actual alignment was detected with superfamily member NF041672:

Pssm-ID: 469554  Cd Length: 360  Bit Score: 700.94  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667   1 MIDLHADLNALLKYVDRYRKYLPISRPSVQRRMQYTY-DNKPLESSSNSdvqKQWDLPPPCNISLAQSRDRAVGTLIGLA 79
Cdd:NF041672    1 MIDLHSDDETLNDYAERYAHLLPPASRQLQQRMDYLSvDDAPWLSGAEL---PAWLESRPCTLSEEQALDRAKGALVGLA 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667  80 VGDAVGTTLEFLPRDRAYVKDMTGGGPFQLRAGEWTDDTSMALCLAETLLEKGDADTICFRNKLLELYQHGYNSSNGVCF 159
Cdd:NF041672   78 VGDAVGTTLEFLPRDKAHVSDMVGGGPFRLKPGEWTDDTSMALCLAETYLEKGRLDITLFRNRLVRWYRNGENSSNGRCF 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 160 DIGNTTRFALEQYLTIGPGWSGNTAPETAGNASIIRQAPVSIFFRKSLSKAFYEAKKQCIATHGAAEAINSTQYLSYLLV 239
Cdd:NF041672  158 DIGNTTRYALEQYLKHGPSWFGNTEPNTAGNAAIIRLAPVAIFRRHSLLATWRDSQAQSRATHCAVESLDSCQLLGLILH 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 240 HMINGSNKDFVFSPHVMPLQPRVMIINAGEYKQKTRDQIRSSGYVIDTLEAAMWSVWNTDNFRDAILLAANLADDADSVA 319
Cdd:NF041672  238 YLLNGADKEEAFSPHVMPLNPRVLIINAGEYKQKTRDQIRSSGYVIDTLEAALWAVWNTDNFRDAILLAANLADDADSVA 317
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2752359667 320 ATAGQIAGALYGYSGIPQEWKNNLVQHERIAKMAGELFDRAPE 362
Cdd:NF041672  318 ATAGQIAGALYGYSGIPQEWVDKLAQHERIATLAEQLFDRAPE 360
 
Name Accession Description Interval E-value
ADPriboarghdlase NF041672
ADP-ribosylarginine hydrolase Tri1;
1-362 0e+00

ADP-ribosylarginine hydrolase Tri1;


Pssm-ID: 469554  Cd Length: 360  Bit Score: 700.94  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667   1 MIDLHADLNALLKYVDRYRKYLPISRPSVQRRMQYTY-DNKPLESSSNSdvqKQWDLPPPCNISLAQSRDRAVGTLIGLA 79
Cdd:NF041672    1 MIDLHSDDETLNDYAERYAHLLPPASRQLQQRMDYLSvDDAPWLSGAEL---PAWLESRPCTLSEEQALDRAKGALVGLA 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667  80 VGDAVGTTLEFLPRDRAYVKDMTGGGPFQLRAGEWTDDTSMALCLAETLLEKGDADTICFRNKLLELYQHGYNSSNGVCF 159
Cdd:NF041672   78 VGDAVGTTLEFLPRDKAHVSDMVGGGPFRLKPGEWTDDTSMALCLAETYLEKGRLDITLFRNRLVRWYRNGENSSNGRCF 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 160 DIGNTTRFALEQYLTIGPGWSGNTAPETAGNASIIRQAPVSIFFRKSLSKAFYEAKKQCIATHGAAEAINSTQYLSYLLV 239
Cdd:NF041672  158 DIGNTTRYALEQYLKHGPSWFGNTEPNTAGNAAIIRLAPVAIFRRHSLLATWRDSQAQSRATHCAVESLDSCQLLGLILH 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 240 HMINGSNKDFVFSPHVMPLQPRVMIINAGEYKQKTRDQIRSSGYVIDTLEAAMWSVWNTDNFRDAILLAANLADDADSVA 319
Cdd:NF041672  238 YLLNGADKEEAFSPHVMPLNPRVLIINAGEYKQKTRDQIRSSGYVIDTLEAALWAVWNTDNFRDAILLAANLADDADSVA 317
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2752359667 320 ATAGQIAGALYGYSGIPQEWKNNLVQHERIAKMAGELFDRAPE 362
Cdd:NF041672  318 ATAGQIAGALYGYSGIPQEWVDKLAQHERIATLAEQLFDRAPE 360
DraG COG1397
ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones];
68-360 1.61e-84

ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441007  Cd Length: 256  Bit Score: 256.71  E-value: 1.61e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667  68 RDRAVGTLIGLAVGDAVGTTLEFLPRDR-----AYVKDMTGGGPfqLRAGEWTDDTSMALCLAETLLEKGDADTICFRNK 142
Cdd:COG1397     2 LDRARGALLGLAIGDALGAPVEFYSREEiraryGPITDYVGGGN--LPPGEWTDDTQMALALAESLLEAGGFDPEDLARR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 143 LLELYQHGYnssngvCFDIGNTTRFALEQYLTigpGWSGNTAPETAGNASIIRQAPVSIFFRKSLSKAFYEAKKQCIATH 222
Cdd:COG1397    80 FLRWLRTGP------GRDIGPTTRRALRNLRR---GGAGESGEGSAGNGAAMRIAPLGLAYAGDPEEAAELARASAALTH 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 223 GAAEAINSTQYLSYLLVHMINGSNKDfvfsphvmplqprvmiinageykqktrdqirsSGYVIDTLEAAMWSVWNTDNFR 302
Cdd:COG1397   151 GHPRAIAGAVAYAAAVAAALRGADLE--------------------------------EGYVVETLPAALWALLRADDFE 198
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2752359667 303 DAILLAANLADDADSVAATAGQIAGALYGYSGIPQEWKNNLVQHERIAKMAGELFDRA 360
Cdd:COG1397   199 EALLLAVNLGGDTDTTAAIAGALAGALYGLEAIPERWLEPLERRDRLEELAERLAALA 256
ADP_ribosyl_GH pfam03747
ADP-ribosylglycohydrolase; This family includes enzymes that ADP-ribosylations, for example ...
73-338 4.49e-50

ADP-ribosylglycohydrolase; This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.


Pssm-ID: 461037 [Multi-domain]  Cd Length: 200  Bit Score: 166.59  E-value: 4.49e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667  73 GTLIGLAVGDAVGTTLEFLPRDR------AYVKDMTGGGPFQLRAGEWTDDTSMALCLAETLLEKGDADticfrnkllel 146
Cdd:pfam03747   1 GALLGLAVGDALGAPVEFWSYDEirreygGIGTPMPGGGHLGLPPGEWTDDTQMALALLESLLEAGGFD----------- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 147 yqhgynssngvcfdignttrfaleqyltigpgwsgntaPETAGNASIIRQAPVSIFFRKSLSKAFYEAKKQCIATHGAAE 226
Cdd:pfam03747  70 --------------------------------------PEDLARRLAMRIAPLGLLYPGDPEEAAELARESARLTHGHPR 111
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 227 AINSTQYLSYLLVHMINGSNKDFVFsphvmplqprvmiinageykqktrDQIRSSGYVIDTLEAAMWSVWN-TDNFRDAI 305
Cdd:pfam03747 112 AVAGAVAYAAAIAAALRGADLEEAL------------------------EAIGGGGYVVEALPAALYALLRaGDDFEEAL 167
                         250       260       270
                  ....*....|....*....|....*....|...
gi 2752359667 306 LLAANLADDADSVAATAGQIAGALYGYSGIPQE 338
Cdd:pfam03747 168 LAAVNLGGDTDTTAAIAGALLGAYYGLEAIPEE 200
 
Name Accession Description Interval E-value
ADPriboarghdlase NF041672
ADP-ribosylarginine hydrolase Tri1;
1-362 0e+00

ADP-ribosylarginine hydrolase Tri1;


Pssm-ID: 469554  Cd Length: 360  Bit Score: 700.94  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667   1 MIDLHADLNALLKYVDRYRKYLPISRPSVQRRMQYTY-DNKPLESSSNSdvqKQWDLPPPCNISLAQSRDRAVGTLIGLA 79
Cdd:NF041672    1 MIDLHSDDETLNDYAERYAHLLPPASRQLQQRMDYLSvDDAPWLSGAEL---PAWLESRPCTLSEEQALDRAKGALVGLA 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667  80 VGDAVGTTLEFLPRDRAYVKDMTGGGPFQLRAGEWTDDTSMALCLAETLLEKGDADTICFRNKLLELYQHGYNSSNGVCF 159
Cdd:NF041672   78 VGDAVGTTLEFLPRDKAHVSDMVGGGPFRLKPGEWTDDTSMALCLAETYLEKGRLDITLFRNRLVRWYRNGENSSNGRCF 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 160 DIGNTTRFALEQYLTIGPGWSGNTAPETAGNASIIRQAPVSIFFRKSLSKAFYEAKKQCIATHGAAEAINSTQYLSYLLV 239
Cdd:NF041672  158 DIGNTTRYALEQYLKHGPSWFGNTEPNTAGNAAIIRLAPVAIFRRHSLLATWRDSQAQSRATHCAVESLDSCQLLGLILH 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 240 HMINGSNKDFVFSPHVMPLQPRVMIINAGEYKQKTRDQIRSSGYVIDTLEAAMWSVWNTDNFRDAILLAANLADDADSVA 319
Cdd:NF041672  238 YLLNGADKEEAFSPHVMPLNPRVLIINAGEYKQKTRDQIRSSGYVIDTLEAALWAVWNTDNFRDAILLAANLADDADSVA 317
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2752359667 320 ATAGQIAGALYGYSGIPQEWKNNLVQHERIAKMAGELFDRAPE 362
Cdd:NF041672  318 ATAGQIAGALYGYSGIPQEWVDKLAQHERIATLAEQLFDRAPE 360
DraG COG1397
ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones];
68-360 1.61e-84

ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441007  Cd Length: 256  Bit Score: 256.71  E-value: 1.61e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667  68 RDRAVGTLIGLAVGDAVGTTLEFLPRDR-----AYVKDMTGGGPfqLRAGEWTDDTSMALCLAETLLEKGDADTICFRNK 142
Cdd:COG1397     2 LDRARGALLGLAIGDALGAPVEFYSREEiraryGPITDYVGGGN--LPPGEWTDDTQMALALAESLLEAGGFDPEDLARR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 143 LLELYQHGYnssngvCFDIGNTTRFALEQYLTigpGWSGNTAPETAGNASIIRQAPVSIFFRKSLSKAFYEAKKQCIATH 222
Cdd:COG1397    80 FLRWLRTGP------GRDIGPTTRRALRNLRR---GGAGESGEGSAGNGAAMRIAPLGLAYAGDPEEAAELARASAALTH 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 223 GAAEAINSTQYLSYLLVHMINGSNKDfvfsphvmplqprvmiinageykqktrdqirsSGYVIDTLEAAMWSVWNTDNFR 302
Cdd:COG1397   151 GHPRAIAGAVAYAAAVAAALRGADLE--------------------------------EGYVVETLPAALWALLRADDFE 198
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2752359667 303 DAILLAANLADDADSVAATAGQIAGALYGYSGIPQEWKNNLVQHERIAKMAGELFDRA 360
Cdd:COG1397   199 EALLLAVNLGGDTDTTAAIAGALAGALYGLEAIPERWLEPLERRDRLEELAERLAALA 256
ADP_ribosyl_GH pfam03747
ADP-ribosylglycohydrolase; This family includes enzymes that ADP-ribosylations, for example ...
73-338 4.49e-50

ADP-ribosylglycohydrolase; This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.


Pssm-ID: 461037 [Multi-domain]  Cd Length: 200  Bit Score: 166.59  E-value: 4.49e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667  73 GTLIGLAVGDAVGTTLEFLPRDR------AYVKDMTGGGPFQLRAGEWTDDTSMALCLAETLLEKGDADticfrnkllel 146
Cdd:pfam03747   1 GALLGLAVGDALGAPVEFWSYDEirreygGIGTPMPGGGHLGLPPGEWTDDTQMALALLESLLEAGGFD----------- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 147 yqhgynssngvcfdignttrfaleqyltigpgwsgntaPETAGNASIIRQAPVSIFFRKSLSKAFYEAKKQCIATHGAAE 226
Cdd:pfam03747  70 --------------------------------------PEDLARRLAMRIAPLGLLYPGDPEEAAELARESARLTHGHPR 111
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2752359667 227 AINSTQYLSYLLVHMINGSNKDFVFsphvmplqprvmiinageykqktrDQIRSSGYVIDTLEAAMWSVWN-TDNFRDAI 305
Cdd:pfam03747 112 AVAGAVAYAAAIAAALRGADLEEAL------------------------EAIGGGGYVVEALPAALYALLRaGDDFEEAL 167
                         250       260       270
                  ....*....|....*....|....*....|...
gi 2752359667 306 LLAANLADDADSVAATAGQIAGALYGYSGIPQE 338
Cdd:pfam03747 168 LAAVNLGGDTDTTAAIAGALLGAYYGLEAIPEE 200
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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