|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
66-297 |
1.35e-104 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 314.08 E-value: 1.35e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 66 RDWERDRGRGARASAVAGATFeRTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEI 145
Cdd:PRK05636 47 TRGGDRRGFKRREESREYRDF-RQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEI 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 146 DPILLAGRLDRTGDLERIGGPLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEPEQLVDEA 225
Cdd:PRK05636 126 DPVIVAGRLDRTNDLERVGGAPYLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEGDEGAEIDSVIDRA 205
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2562481267 226 QQLIFSVGRENTKNDYVPIADVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK05636 206 QQEVFAVSQKNQSEDYAVLADILDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVG 277
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
90-297 |
1.54e-97 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 293.56 E-value: 1.54e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 90 PPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYL 169
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 170 HTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDtePEQLVDEAQQLIFSVGRENTKNDYVPIADVLD 249
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGD--VEELLDEAEQKIFEIAESRTSKGFKSIKEILK 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2562481267 250 DTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:TIGR00665 159 EAVEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMG 206
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
93-297 |
5.23e-93 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 281.97 E-value: 5.23e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 93 NIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYLHTL 172
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 173 ASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYagAEDTEPEQLVDEAQQLIFSVGRENTKNDYVPIADVLDDTL 252
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAY--DEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEAL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2562481267 253 EELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:COG0305 159 ERIEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMG 203
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
89-191 |
9.99e-42 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 139.68 E-value: 9.99e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 89 TPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLY 168
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|...
gi 2562481267 169 LHTLASLVPTAANAQFYARIVAE 191
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIVKE 103
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
267-297 |
2.00e-11 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 62.91 E-value: 2.00e-11
10 20 30
....*....|....*....|....*....|.
gi 2562481267 267 GVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMG 31
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
66-297 |
1.35e-104 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 314.08 E-value: 1.35e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 66 RDWERDRGRGARASAVAGATFeRTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEI 145
Cdd:PRK05636 47 TRGGDRRGFKRREESREYRDF-RQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEI 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 146 DPILLAGRLDRTGDLERIGGPLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEPEQLVDEA 225
Cdd:PRK05636 126 DPVIVAGRLDRTNDLERVGGAPYLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEGDEGAEIDSVIDRA 205
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2562481267 226 QQLIFSVGRENTKNDYVPIADVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK05636 206 QQEVFAVSQKNQSEDYAVLADILDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVG 277
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
90-297 |
1.54e-97 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 293.56 E-value: 1.54e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 90 PPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYL 169
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 170 HTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDtePEQLVDEAQQLIFSVGRENTKNDYVPIADVLD 249
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGD--VEELLDEAEQKIFEIAESRTSKGFKSIKEILK 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2562481267 250 DTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:TIGR00665 159 EAVEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMG 206
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
93-297 |
5.23e-93 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 281.97 E-value: 5.23e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 93 NIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYLHTL 172
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 173 ASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYagAEDTEPEQLVDEAQQLIFSVGRENTKNDYVPIADVLDDTL 252
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAY--DEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEAL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2562481267 253 EELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:COG0305 159 ERIEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMG 203
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
71-297 |
1.20e-86 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 277.02 E-value: 1.20e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 71 DRGRGARASAvAGATFERTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILL 150
Cdd:PRK07773 6 DLAPGMDSSP-PSEDYGRQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 151 AGRLDRTGDLERIGGPLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYagAEDTEPEQLVDEAQQLIF 230
Cdd:PRK07773 85 AAELDRRGLLERIGGAPYLHTLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGY--AEGADVAEVVDRAQAEIY 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2562481267 231 SVGRENTKNDYVPIADVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK07773 163 DVTDRRLSEDFVALEDLLQPTFDEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMG 229
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
86-297 |
1.53e-73 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 232.54 E-value: 1.53e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 86 FERTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGG 165
Cdd:PRK05748 6 ALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDLEEVGG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 166 PLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEdtEPEQLVDEAQQLIFSVGRENTKNDYVPIA 245
Cdd:PRK05748 86 LSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPED--DADEILDEAEKKIFEVSERRNKSGFKNIK 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2562481267 246 DVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK05748 164 DVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVG 215
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
88-297 |
6.64e-59 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 194.66 E-value: 6.64e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK05595 6 RSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAGGVT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTepEQLVDEAQQLIFSVGRENTKNDYVPIADV 247
Cdd:PRK05595 86 YITELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDV--EKVIDSAEKKIFDISEKRTTSDFEPLSNV 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2562481267 248 LDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK05595 164 LERGFEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMG 213
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
66-297 |
4.28e-49 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 169.71 E-value: 4.28e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 66 RDWERDRGRGARASAVAGATFERTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEI 145
Cdd:PRK08760 9 SNRNRDRDDDDYDRPEPRLDQLRVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 146 DPILLAGRLDRTGDLERIGGPLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgAEDTEPEQLVDEA 225
Cdd:PRK08760 89 DAVTLGEWFESQGKLEQVGDGAYLIELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQ-PEGRESIELLASA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2562481267 226 QQLIFSVGRENT--KNDYVPIADVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK08760 168 EKAVFKIAEAGArgRTDFVAMPGALKDAFEELRNRFENGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMG 241
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
88-297 |
4.97e-45 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 158.89 E-value: 4.97e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK09165 19 RELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLENDEALGELGGVQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEPEQLVDEAQQLIFSVGrENTKND--YVPIA 245
Cdd:PRK09165 99 YLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDAPVDVAPQEQIEDAEQKLYELA-ETGRYEggFQSFG 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2562481267 246 DVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK09165 178 TAITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMG 229
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
90-297 |
6.20e-44 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 155.92 E-value: 6.20e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 90 PPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYL 169
Cdd:PRK06904 23 PPHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKSDEVGGFAYL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 170 HTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgAEDTEPEQLVDEAQQLIFSVGRENTKNDYVP--IADV 247
Cdd:PRK06904 103 AELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYS-PKGQDIKDILDEAERDVFSIAEKRTTANEGPqnVINL 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2562481267 248 LDDTLEELDLITQ---NGGLAqGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK06904 182 LENTIDKIENLAAtptNNGVT-GVTTGFTDLDKKTAGLQPSDLIIVAARPSMG 233
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
88-297 |
2.99e-43 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 154.01 E-value: 2.99e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK08006 25 KVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYaGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVP--IA 245
Cdd:PRK08006 105 YLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGY-DPQGRTSEDLLDLAESRVFQIAESRANKDEGPknIA 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2562481267 246 DVLDDTLEELDLITQ--NGGLAqGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK08006 184 DILDATVARIEQLFQqpHDGVT-GVNTGYDDLNKKTAGLQPSDLIIVAARPSMG 236
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
88-297 |
5.63e-42 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 150.52 E-value: 5.63e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK08840 18 KVPPHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLEDVGGFA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYaGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVP--IA 245
Cdd:PRK08840 98 YLADLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGY-DPQGRTSEDLLDMAESKVFAIAEARTSENEGPqnVD 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2562481267 246 DVLDDTLEELDLI---TQNGglAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK08840 177 SILEKTLERIELLyktPQDG--VTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMG 229
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
88-297 |
6.05e-42 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 150.06 E-value: 6.05e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK07004 13 KVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEVGGLA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgAEDTEPEQLVDEAQQLIFSVGRENTKND--YVPIA 245
Cdd:PRK07004 93 YLNALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFN-PQGKEVRQLLDEAESKVFSIAEEGARGTqgFLEIG 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2562481267 246 DVLDDTLEELDLI--TQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK07004 172 PLLTQVVERIDTLyhTANPSDVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMG 225
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
89-191 |
9.99e-42 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 139.68 E-value: 9.99e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 89 TPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLY 168
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|...
gi 2562481267 169 LHTLASLVPTAANAQFYARIVAE 191
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIVKE 103
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
89-297 |
1.07e-32 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 125.34 E-value: 1.07e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 89 TPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLY 168
Cdd:PRK06321 15 SPPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLNVIGGPSY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 169 LHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQigYAGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVPIADVL 248
Cdd:PRK06321 95 LITLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEK--KALEEPKDVATALDEAQNLLFKISQTTNLAQYVLVADKL 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2562481267 249 DDTLEELDLI-----------------TQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK06321 173 KGLTSSKDKPfllqlqerqeafqqsaqGDSSPMISGIPTHFIDLDKMINGFSPSNLMILAARPAMG 238
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
92-297 |
2.39e-29 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 116.26 E-value: 2.39e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 92 HNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTgdlERIGGPLYLHT 171
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKD---KKIDEEILLEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 172 LASlvPTAANAQFYARIVAEKATIRRLVEAGTKIAQIgyAGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVPIADVLDDT 251
Cdd:PRK08506 82 LAT--NPIDNIEAYVEEIKEKSIKRELLSLANTIPEQ--AVEEDQKSSDILDEVERELYSITNGSNSEDFKDSKEVIEST 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2562481267 252 LEEL-DLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK08506 158 MEHIkKQKRLGNKDIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMG 204
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
93-297 |
1.95e-25 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 104.65 E-value: 1.95e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 93 NIEAEQSVLGAMLLNSEVVADVyeQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGdLERIGGPLYLHTL 172
Cdd:PRK06749 5 NVEAEKTVLGSLLLDGELIKEC--RLTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTSRVDPNF-LKGIGGMEYFIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2562481267 173 ASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEPEQLVDEAQQLifsvgRENTKNDYVPIADVLDDTL 252
Cdd:PRK06749 82 MDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCEL-----EEKDCVCEFDLKDALVDLY 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2562481267 253 EELDlitQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:PRK06749 157 EELH---QDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMG 198
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
267-297 |
1.97e-12 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 65.51 E-value: 1.97e-12
10 20 30
....*....|....*....|....*....|.
gi 2562481267 267 GVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMG 31
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
267-297 |
2.00e-11 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 62.91 E-value: 2.00e-11
10 20 30
....*....|....*....|....*....|.
gi 2562481267 267 GVPTGITNLDKLTNGLHPGQMVIIAARPGVG 297
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMG 31
|
|
| |
