|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13571 |
PRK13571 |
anthranilate synthase component I; Provisional |
20-505 |
0e+00 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184152 [Multi-domain] Cd Length: 506 Bit Score: 715.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 20 GATWPSLGTFRELARTRRVVPVVRRLLADDVTPVGLYRTLAQGRPGTFILESAEVDGTWARYSFVGVRSRATLTVADGEA 99
Cdd:PRK13571 4 GAATTSREDFRALAAEHRVVPVTRKVLADSETPVGAYRKLAANRPGTFLLESAENGRSWSRWSFIGVGSPAALTVRDGEA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 100 TWTGDVPVGVPVTGDVLEVLGETLEVLRTPAIAGLPPLTGGLVGAMGWDVVRHWEpTLPAKAPDELGVPELTLCLATDLA 179
Cdd:PRK13571 84 VWLGTPPAGAPTGGDPLAALRATLELLATPRLPGLPPLTGGMVGFLGYDAVRRLE-RLPELAVDDLGLPEMLLLLATDLA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 180 VVDHVDGSVWLVANAINFDATDERVDEAHADAVARLDAMQTALAAPVHVPPAVLgAGPEPELEFRSTRQEFEEAVRAGKE 259
Cdd:PRK13571 163 AVDHHEGTITLIANAVNWNGTDERVDAAYDDAVARLDVMTAALAQPLPSTVATF-SRPVPEFRAQRTVEEFGAAVEKLVE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 260 AIRDGEVFQVVLSQRLDLDCPASPLDVYRVLRTINPSPYMYCFQLQDA-AGHDFAVVGSSPETLVKVTDGRVLTYPIAGS 338
Cdd:PRK13571 242 EIRAGEAFQVVPSQRFEMDTTADPLDVYRVLRVTNPSPYMYLLRVPNSdGGTDFSIVGSSPEALVTVTDGRATTHPIAGT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 339 RPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQ 418
Cdd:PRK13571 322 RWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLGRVCRPGTVRVVDFSHIERYSHVMHLVSTVTGELAEGRTALD 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 419 TLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALE 498
Cdd:PRK13571 402 AVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIAIRTALMRDGTAYVQAGGGVVADSDPDYE 481
|
....*..
gi 2541321043 499 YAESRNK 505
Cdd:PRK13571 482 DNEARNK 488
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
46-505 |
0e+00 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 596.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 46 LADDVTPVGLYRTLAQGrPGTFILESAEVDGTWARYSFVGVRSRATLTVADGEATWTGDVPVgVPVTGDVLEVLGETLEV 125
Cdd:COG0147 9 LLALETPVSLFLKLADG-PYAFLLESAEGGEKWGRYSFIGADPLATLTVRGGRVTIEGGGEV-EPSEGDPLDALRALLAR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 126 LRTPAIAGLPPLTGGLVGAMGWDVVRHWEPtLPAKAPDELGVPELTLCLATDLAVVDHVDGSVWlvanaiNFdatdervd 205
Cdd:COG0147 87 FRLPPLPGLPPFTGGLVGYFGYDLVRYFER-LPDLAPDDLGLPDAALGLYDRLLVFDHLKGTRS------NF-------- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 206 eahadavarldamqtalaapvhvppavlgagpepelefrsTRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLD 285
Cdd:COG0147 152 ----------------------------------------TREEYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEGDPLA 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 286 VYRVLRTINPSPYMYCFQLqdaagHDFAVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEH 365
Cdd:COG0147 192 LYRALRRINPSPYMFYLRF-----GDFAIVGSSPERLVRVEDGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEH 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 366 IMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELE 445
Cdd:COG0147 267 LMLVDLARNDLGRVCEPGSVKVPELMVVERYSHVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELE 346
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 446 PARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:COG0147 347 PTRRGVYGGAVGYLSFDGNMDLAIAIRTAVVKDGRAYVQAGAGIVADSDPEAEYQETLNK 406
|
|
| trpE_most |
TIGR00564 |
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some ... |
47-505 |
0e+00 |
|
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. Archaeal enzymes have been excluded from this model (and are now found in TIGR01820) as have a clade of enzymes which constitute a TrpE paralog which may have PabB activity (TIGR01824). This allows the B. subtilus paralog which has been shown to have PabB activity to score below trusted to this model. This model contains sequences from gram-positive bacteria, certain proteobacteria, cyanobacteria, plants, fungi and assorted other bacteria.A second family of TrpE enzymes is modelled by TIGR00565. The breaking of the TrpE family into these diverse models allows for the separation of the models for the related enzyme, PabB. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273142 [Multi-domain] Cd Length: 454 Bit Score: 556.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 47 ADDVTPVGLYRTLAQgrPGTFILESAEVDGTWARYSFVGVRSRATLTVADGEATWTGDVPVGVPVTG--DVLEVLGETLE 124
Cdd:TIGR00564 1 ADTLTPISAYLKLAQ--PGSFLLESAEPGSERGRYSFIGLNPVLTIKTEGGTEYLGADDRRSGIVGNplDEIRDVMETFA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 125 VLRTPAIAglPPLTGGLVGAMGWDVVRHWEPtLPAKAPDELGVPELTLCLATDLAVVDHVDGSVWLVANAINFDATDerv 204
Cdd:TIGR00564 79 QHSDPELP--IPFTGGAVGYLGYDTVRLFEK-ITLPPPDPLNLPDAYLMLCDDFIIFDHVTDKLYLIHNNRTTASRS--- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 205 deAHADAVARLDAMQTALAAPVhvPPAVlGAGPEPELEFRS--TRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPAS 282
Cdd:TIGR00564 153 --AKAAADARLEALVADLQDPL--LPEV-PVPYPAALSFTSnyEKEEYEANVAKAKEYIKAGDIFQVVLSQRFEAKTEAP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 283 PLDVYRVLRTINPSPYMYCFQLQDaaghdFAVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKER 362
Cdd:TIGR00564 228 PFELYRVLRIVNPSPYMYYLDFGD-----FQIVGSSPELLVKVTGGRITTRPIAGTRKRGATPEEDEALAEELLADEKER 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 363 AEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALID 442
Cdd:TIGR00564 303 AEHLMLVDLGRNDIGRVCEPGSVEVPEFMKIERYSHVMHIVSTVEGRLKDGLTAIDALRATFPAGTVSGAPKIRAMELID 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2541321043 443 ELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:TIGR00564 383 ELEPEKRGIYGGAVGYLSFDGDMDTAIAIRTMVVKDGKAYVQAGGGIVADSDPEAEYEETLNK 445
|
|
| TrpE-arch |
TIGR01820 |
anthranilate synthase component I, archaeal clade; This model represents an archaeal clade of ... |
52-505 |
2.84e-143 |
|
anthranilate synthase component I, archaeal clade; This model represents an archaeal clade of anthranilate synthase component I enzymes. This enzyme is responsible for the first step of tryptophan biosynthesis from chorismate. The Sulfolobus enzyme has been reported to be part of a gene cluster for Trp biosynthesis [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273819 [Multi-domain] Cd Length: 435 Bit Score: 419.46 E-value: 2.84e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 52 PVGLYRTLAQGRPGTFILESAEVDGTWARYSFVGVRSRATLTVADGeatwtGDVPVGVPVTGDVLEVLGETLEVLRTPAI 131
Cdd:TIGR01820 1 PLELYKAIRADGDYAFLLESAEKPSKKARYSFIGWDPEFVVRINGK-----GKSVEGIPEDGDVVDKLRNAFPKLKGINI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 132 AGLPP-LTGGLVGAMGWDVVRH-WEPTLPAKAPDElGVPELTLCLATDLAVVDHVDGSVWLVAnainfdaTDERVDEAHA 209
Cdd:TIGR01820 76 PGEDRrFKGGLVGYIAYDAVRDyWEGIVDLKRKAE-DWPPAEFFIYPNTIVYDHLEGKVYYVS-------TPEPEAELER 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 210 DAVARLDAMQTAlaapvhvppavlGAGPEPELEFRSTRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLDVYRV 289
Cdd:TIGR01820 148 IVERAKRATDPG------------EAGVSFEGESLSDREEFEEAVEEAKEYIFAGDIFQVVLSREYEYRLDGDPFELYYN 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 290 LRTINPSPYMYCFQLQDAAghdfaVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLV 369
Cdd:TIGR01820 216 LREINPSPYMFLLKFGDRY-----LVGSSPETLVRVEGRTVETNPIAGTRPRGATPEEDERLAKELLSDEKERAEHVMLV 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 370 DLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARR 449
Cdd:TIGR01820 291 DLARNDVRKVSEPGSVKVPEFMYVEKYSHVQHIESTVIGTLKKDYDAFDALRATFPAGTLSGAPKIRAMEIIDELEKEPR 370
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 2541321043 450 GIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:TIGR01820 371 GVYGGGVGYFSWNGDADFAIAIRTAEIDKDKLRIQAGAGIVADSIPEREFEETENK 426
|
|
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
248-505 |
4.11e-124 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 363.80 E-value: 4.11e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 248 QEFEEAVRAGKEAIRDGEVFQVVLSQRLDL--DCPASPLDVYRVLRTINPSPYMYCFQLQDaaghdFAVVGSSPETLVKV 325
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLplAGDIDPLALYRRLRARNPAPYSFYFRTGD-----FTFLGASPERLLSV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 326 TDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICST 405
Cdd:pfam00425 76 DGGRIITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVST 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 406 VVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQA 485
Cdd:pfam00425 156 ISGRLKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYA 235
|
250 260
....*....|....*....|
gi 2541321043 486 GGGIVADSVEALEYAESRNK 505
Cdd:pfam00425 236 GAGIVADSDPEAEWEETEAK 255
|
|
| PLN02445 |
PLN02445 |
anthranilate synthase component I |
45-505 |
1.67e-119 |
|
anthranilate synthase component I
Pssm-ID: 215244 [Multi-domain] Cd Length: 523 Bit Score: 361.69 E-value: 1.67e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 45 LLADDVTPVGLYRTLA----QGRPgTFILESAE---VDGTWARYSFVGVRSR----AT---LTVADGEA-TWTgdvpvgV 109
Cdd:PLN02445 17 IFSDHLTPVLAYRCLVkeddREAP-SFLFESVEpgsQSSNVGRYSVVGAQPAmeivAKenkVTIMDHEKgTRT------E 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 110 PVTGDVLEVLGETLEVLRTPAIAGLPP-LTGGLVGAMGWDVVRHWEPT-LP-AKAP-DELGVPELTLCLATDLAVVDHVD 185
Cdd:PLN02445 90 EIVEDPMEIPRRISEKWNPQLIDGLPDvFCGGWVGYFSYDTVRYVEKKkLPfSGAPeDDRNLPDIHLGLYDDVIVFDHVE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 186 GSVWLVaNAINFDATDErVDEAHADAVARLDAMQTALAAPVhVPPAVLGA--------GPEPElEFRSTRQEFEEAVRAG 257
Cdd:PLN02445 170 KKAYVI-HWVRLDRYSS-VEEAYEDGMKRLEALVSRLQDIN-PPKLSPGSvklstnqfGPSLE-KSNMTSEEYKNAVLQA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 258 KEAIRDGEVFQVVLSQRLDLDCPASPLDVYRVLRTINPSPYMYCFQLQDAAghdfaVVGSSPETLVKVTDGRVLTYPIAG 337
Cdd:PLN02445 246 KEHILAGDIFQIVLSQRFERRTFADPFEVYRALRIVNPSPYMIYLQARGCI-----LVASSPEILTRVKKNKIVNRPLAG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 338 SRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATAL 417
Cdd:PLN02445 321 TRRRGKTPEEDKALEKDLLADEKQCAEHIMLVDLGRNDVGKVSKAGSVKVEKLMNIERYSHVMHISSTVTGELLDHLTSW 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 418 QTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGR----------------- 480
Cdd:PLN02445 401 DALRAALPVGTVSGAPKVRAMELIDELEVTRRGPYSGGFGGVSFTGDMDIALALRTMVFPTAArydtmysykdtnsrrew 480
|
490 500
....*....|....*....|....*.
gi 2541321043 481 -ASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PLN02445 481 vAHLQAGAGIVADSDPEDEYRECVNK 506
|
|
| PRK13572 |
PRK13572 |
anthranilate synthase component I; Provisional |
48-505 |
6.17e-108 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 237432 [Multi-domain] Cd Length: 435 Bit Score: 329.01 E-value: 6.17e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 48 DDVTPVGLYRTLAQ-GRPgtFILESAEVDGTWARYSFVGVRSRATLTVADGEatwtgdvpvgvpvtgdvlEVLGETLEVL 126
Cdd:PRK13572 7 DYVNPLKLYSVLRDeGYP--FILESAEKGQRKARYTYISANPEFMVRIGNKT------------------KVDGETISKE 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 127 RTP--AIAGLPP-------LTGGLVGAMGWDVVRHWEPTLPaKAPDELGVPELTLclatdlaVVDHVDGSVWLVA----- 192
Cdd:PRK13572 67 SNPfkALKENFKitqsgdrFTGGFVGYIAYDAVHNYIGGKI-EEPSVFGYYDHVF-------VYDHVTRKFYFHSlnnnp 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 193 -NAINFDATDERV------DEAHADAVARLDAmqtalaapvhvppavlgagpepelefrsTRQEFEEAVRAGKEAIRDGE 265
Cdd:PRK13572 139 eELFNAEKIVEKAkrfeieEEDGGSEVLGCDA----------------------------DREEFVEMVEKAKEYIYSGD 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 266 VFQVVLSQRLDLDCPASPLDVYRVLRTINPSPYMYCFQLqdaaghDFAVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGP 345
Cdd:PRK13572 191 VFQVVLSREYRLKTDLSPFQLYRNLREINPSPYMFLLEF------DKDVVGASPETMASVENNILKINPIAGTAPRGKTE 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 346 EEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFP 425
Cdd:PRK13572 265 EEDKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYSHVQHIESEVVGELKEDSTMFDAIEAAFP 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 426 AGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIrDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK13572 345 AGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMAEI-DKVCRVRAGAGIVADSVPEKEFYETERK 423
|
|
| PRK05940 |
PRK05940 |
anthranilate synthase component I; |
109-505 |
2.34e-107 |
|
anthranilate synthase component I;
Pssm-ID: 235651 [Multi-domain] Cd Length: 463 Bit Score: 328.61 E-value: 2.34e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 109 VPVTGDVLEVLGETLE--VLRTPAIAGLPpLTGGLVGAMGWDVVrhWE-PTLPAKAPDELGVPELTLCLATDLAVVDHVD 185
Cdd:PRK05940 67 TPKLGEILPFLRQLLArsLDPSALPEHLP-FTGGWLGWLGYDLA--WEiERLPHLNPDPLPFPVAYWYEPESFAILDHQE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 186 GSVWLVAnainfdatdervdeahaDAVARLDAMQTALAAPVHVPPAVLGAGPEP-ELEFRSTRQEFEEAVRAGKEAIRDG 264
Cdd:PRK05940 144 QILWLAA-----------------SDPSQLDRLEQQLEQPTPEPDLPLDLRTPPsSLIFYTTQQEYEAAVRQAKKYIQAG 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 265 EVFQVVLSQRLDLDCPASPLDVYRVLRTINPSPYMyCFqLQDAAGhdfAVVGSSPETLVKVTDGRVLTYPIAGSRPRGAG 344
Cdd:PRK05940 207 DIFQANLSLRFQTTTSADSWQIYRRLQQINPSPFA-SY-WRTPWG---DVVSCSPERLVQLQGNQAQTRPIAGTRPRGKT 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 345 PEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATF 424
Cdd:PRK05940 282 PAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQWGSVEVDELLTIERYSHVIHLVSNVVGTLQPNRDAIDLIRALF 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 425 PAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTAL---IRDGRASV--QAGGGIVADSVEALEY 499
Cdd:PRK05940 362 PGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLDLNILIRTLLytpLSRGLSTIwgQVGAGIVADSDPEKEW 441
|
....*.
gi 2541321043 500 AESRNK 505
Cdd:PRK05940 442 LESLQK 447
|
|
| PRK13574 |
PRK13574 |
anthranilate synthase component I; Provisional |
68-505 |
9.49e-107 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184155 [Multi-domain] Cd Length: 420 Bit Score: 325.23 E-value: 9.49e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 68 ILESAEVDGTWARYSFVGVRSRATLTVADgeatwtgdvpvgvpvtgDVLEVLGETLEVLRTPAIAGLppLTGGLVGAMGW 147
Cdd:PRK13574 28 LLESIGGPQYKARYSVIAWGTNGYLKIHD-----------------DPVNILNSYLKDLKLVDIPGL--FKGGMIGYISY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 148 DVVRHWEPTLPAK-APDELgvPELTLCLATDLAVVDHVDGSVWLVANAinfdatdervdeahadavarldamqtalaapv 226
Cdd:PRK13574 89 DAVRFWEKIRDLKpAAEDW--PYAEFFIPDNIIIYDHNEGKVYVNGDL-------------------------------- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 227 hvpPAVLGAGPEPELEFRS-----TRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLDVYRVLRTINPSPYMYC 301
Cdd:PRK13574 135 ---SSVGGCGDMGEFKISFydeslNKNNYEKIVSESLEYIRSGYIFQVVLSRFYRYLFSGDPLRIYYNLRRINPSPYMFY 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 302 FQLQDAAghdfaVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCV 381
Cdd:PRK13574 212 LKFDERY-----LIGSSPELLFRVQDNIVETYPIAGTRPRGSDQEEDLKLELELMNSEKDKAEHLMLVDLARNDLGKVCV 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 382 PTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDF 461
Cdd:PRK13574 287 PGTVRVPELMYVEKYSHVQHIVSKVIGTLKKKYNALDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISA 366
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2541321043 462 AGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK13574 367 DGNAEFAIAIRTAFLNKDLLRIQAGAGIVYDSNPESEYFETEHK 410
|
|
| PRK13564 |
PRK13564 |
anthranilate synthase component 1; |
52-505 |
8.46e-102 |
|
anthranilate synthase component 1;
Pssm-ID: 237428 [Multi-domain] Cd Length: 520 Bit Score: 316.01 E-value: 8.46e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 52 PVGLYRTLAQGRPGTFILESAEVDGTWARYSFVGVRSRATLTVADGEATWTG----------------DVPVGVPVTGDV 115
Cdd:PRK13564 21 PTALFHQLCGDRPATLLLESAEIDSKDNLKSLLLVDSALRITCLGNTVTIQAltdngaallplldealPAGVENEQDPNG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 116 LEV--------LGE--------TLEVLR-------TPAIAGLPPLTGGLvgaMGWDVVRHWEPtLPAkapdelgVPELTL 172
Cdd:PRK13564 101 LVLtfppvsplLDEdarlkslsVFDALRllqklvnTPKEEREALFLGGL---FAYDLVAGFEP-LPQ-------LPAGNN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 173 C------LATDLAVVDHVDGSVWLVANAINFDATDervdeaHADAVARLDAMQTALAAPVHVPPAVlgAGPEPELEFRST 246
Cdd:PRK13564 170 CpdycfyLAETLLVIDHQKKSARLQASLFTPDEEE------KQRLAARLAQLKQQLTQPAPPLPVT--SVPDMEVSVNIS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 247 RQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPaSPLDVYRVLRTINPSPYMycFQLQDAaghDFAVVGSSPETLVKVT 326
Cdd:PRK13564 242 DEEFCAVVRKLKEHIRAGDIFQVVPSRRFSLPCP-SPLAAYRVLKKSNPSPYM--FYMQDE---DFTLFGASPESALKYD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 327 --DGRVLTYPIAGSRPRGAGP------EEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSH 398
Cdd:PRK13564 316 asSRQVEIYPIAGTRPRGRRAdgsidrDLDSRIELELRTDHKELAEHLMLVDLARNDLARICQPGSRYVADLLKVDRYSH 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 399 IMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRD 478
Cdd:PRK13564 396 VMHLVSRVVGELRHDLDALHAYRACMNMGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTCIVIRSAFVEN 475
|
490 500
....*....|....*....|....*..
gi 2541321043 479 GRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK13564 476 GIATVQAGAGVVLDSDPQSEADETRNK 502
|
|
| PRK09070 |
PRK09070 |
aminodeoxychorismate synthase component I; |
49-505 |
5.05e-99 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236371 [Multi-domain] Cd Length: 447 Bit Score: 306.24 E-value: 5.05e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 49 DVTPVGLYRTLAQGRPgtFILESAEVDGTWARYSFvgvrsratLTVADGE-ATWTGDVPVGVPVTGDVLEVLGETLEVLR 127
Cdd:PRK09070 10 DIDLLALHRLAPERYP--ALLESSASGTAQGRWDV--------LLLAQGKcLRLDPDGVTRQLLEGDFLDALDAAWQAER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 128 TPAIAGLP-PLTGGLVGAMGWDVVRHWEPTLPAKAPDElGVPeLTLCLATDLAV-VDHVDGSVWLVANAinfdATDERVD 205
Cdd:PRK09070 80 VPHDGESSlPFRGGWAVLLDYELAGQVEPILKLPMRTD-GLP-LALALRAPAAVlRDRHSGRCVLVAEP----GREHLLD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 206 EAHADaVARLDAMQtalAAPVHVPPAVLGAGPEpelefrstrQEFEEAVRAGKEAIRDGEVFQVVLSQ--RLDLDCPASP 283
Cdd:PRK09070 154 QIEAD-LAACAALP---PLPVWLAPQAVEEDPP---------ERFTDGVERVLDYIRAGDVFQVNLSRawQAQFANAVDP 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 284 LDVYRVLRTINPSPYMYCFQlqdaaGHDFAVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGpEEDAALAEELLADPKERA 363
Cdd:PRK09070 221 AALYARLRAANPAPFSGLFV-----AAGRAIVSSSPERLVSVQGGVVQTRPIAGTRPRFAG-DDDAALIRELVGHPKERA 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 364 EHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDE 443
Cdd:PRK09070 295 EHVMLIDLERNDLGRICAPGSVEVDELMTVESYAHVHHIVSNVRGRLRDGVTPGEVIRAVFPGGTITGCPKVRCMQIIAE 374
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2541321043 444 LEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK09070 375 LEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGNQVRFRTGAGIVVDSDPERELDETRAK 436
|
|
| trpE_proteo |
TIGR00565 |
anthranilate synthase component I, proteobacterial subset; This enzyme resembles some other ... |
52-505 |
2.88e-97 |
|
anthranilate synthase component I, proteobacterial subset; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. This group includes proteobacteria such as E. coli and Helicobacter pylori but also the gram-positive organism Corynebacterium glutamicum. The second group includes eukaryotes, archaea, and most other bacterial lineages; sequences from the second group may resemble pabB more closely than other trpE from this group. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273143 [Multi-domain] Cd Length: 498 Bit Score: 303.74 E-value: 2.88e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 52 PVGLYRTLAQGRPGTFILESAEVDGTWARYSFVGVRSRATLTVADGEATWTGDVPVGVPV--------TGDVLEVLGETL 123
Cdd:TIGR00565 5 PTALFEKLCQSNPHTLLLESAEIESKAHLKSLLLVKAALKITCLGNIVTITALTPNGGAFlqklsaflKAPVSAVIQDNA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 124 EVLRTPAIAGL---------------------------PPLTGGLVGAMGWDVVRHWEPtLPAKAPDELGVPELTLCLAT 176
Cdd:TIGR00565 85 LILTFTPNKKTldedlklfspspfdalrlfkslktkpkHPFTLFSGGLFSYDLVAFFED-LPHLKAKNNNCPDFIFYLAE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 177 DLAVVDHVDGSVWLVANAInfdatDERVDEAHADAVARLDAMQTALAAPvHVPPAvlgAGPEPELEFRSTRQEFEEAVRA 256
Cdd:TIGR00565 164 NLIIIDHQEKSVEILGACF-----AERFETQIAQALQDLKELQKSIKSD-FVPKK---SKQSREVSANCSDSEFEGRVLS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 257 GKEAIRDGEVFQVVLSQRLDLDCPaSPLDVYRVLRTINPSPYMycFQLQDaagHDFAVVGSSPETLVK--VTDGRVLTYP 334
Cdd:TIGR00565 235 LQEEIKKGEIFQAVPSRRFSLECP-EGLAAYYHLKLTNPSPYM--FYMKD---SDFILFGASPESALKynALTRQAEIYP 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 335 IAGSRPRG------AGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVG 408
Cdd:TIGR00565 309 IAGTRPRGkdaqgnIDYDLDSRMELELRHDHKERAEHLMLVDLARNDMARVCKSGKRYVAKLLKVDRYSNVMHLVSRVVG 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 409 RLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGG 488
Cdd:TIGR00565 389 ELRKGLDALHAYRACMNMGTLSGAPKISAMQLIYQLENQRRGSYGGAVGYLTSEGSMDTCIVIRSAFVKNGRAVVQAGAG 468
|
490
....*....|....*..
gi 2541321043 489 IVADSVEALEYAESRNK 505
Cdd:TIGR00565 469 IVLDSVPQNEADETRAK 485
|
|
| PabB-clade2 |
TIGR01824 |
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely ... |
139-505 |
1.71e-92 |
|
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.
Pssm-ID: 130883 Cd Length: 355 Bit Score: 286.28 E-value: 1.71e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 139 GGLVGAMGWDVVRHWEPtLPAKAPDELGVPELTLCLATDLAVVDHVDGSVWLVANainfDATDERVDEAHADAVARLDAM 218
Cdd:TIGR01824 1 GGRLGWLAYDVARRLEG-IPDLGTSDGGWPVAADFRYEAAVARDHQRQIVALATV----PAETEGEFATSSDQLPAVAAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 219 qTALAAPVHVPPAVlgagpepELEFRSTRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPA--SPLDVYRVLRTINPS 296
Cdd:TIGR01824 76 -TSLPSPDVGPLPV-------DLEASIDRAAYETGVRRIKDYIRAGDVFQANLSRRLTAPIAAdvDPLQLFLALRAPNPA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 297 PYMYCFQLqdaagHDFAVVGSSPETLVKVtDGRVL-TYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRND 375
Cdd:TIGR01824 148 PYAIYLEE-----PGVDVASASPELFLAR-EGRVVqTRPIAGTRPRGATLAEDGALAAELLQHDKDRAEHVMIVDLERND 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 376 LVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGT 455
Cdd:TIGR01824 222 LGRVCATGTVRVPELCAVESYSHVHHLVSRVTGRLREGAGLADLIRALFPGGSITGAPKVRAMEIIDELEPQPRGPYTGS 301
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2541321043 456 VGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:TIGR01824 302 VGWIDADGNADLNILIRTLEGGGAQLHFRTGAGIVADSDPAGEWDETEAK 351
|
|
| PRK13567 |
PRK13567 |
anthranilate synthase component I; Provisional |
49-505 |
1.46e-79 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184148 [Multi-domain] Cd Length: 468 Bit Score: 256.61 E-value: 1.46e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 49 DVTPvglyRTLAQGRPGTFILESAEVDGTWARYSFVGVRSRATLTVADGEATWTGD----VPVGVP-------VTGDVLE 117
Cdd:PRK13567 11 NVTP----EVLAQLHSKKIILESTNQQQTKGRYSVVIFDIYGTLTLDNDVLSVSTLkesyQITERPyhylttkINEDYHN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 118 VLGETLEVLrtpaiaglpPLTGGLVGAMGWDVVRHWEPTLPAKAPDELGVPELTLCLATDLAVVDHVDGSVWLVANAINF 197
Cdd:PRK13567 87 IQDEQLKSL---------PFISGYVGTCSFDLVRHEFPKLQSIQLEDHKQHDVRLYMVEQVYVFDHYKDELYIIATNQFS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 198 DATDERVDEAHADAVARLDAMQtalaaPVHvppavlgagpePELEFRSTRQE---------FEEAVRAGKEAIRDGEVFQ 268
Cdd:PRK13567 158 NSTKSDLENRVNKSIEDLTKIQ-----PFM-----------PTQDFDFKTKEiqsniseerFIEMIQYFKEKITEGDMFQ 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 269 VVLSQRLDLDCPAS----PL--DVYRVLRTINPSPYMYCFQLQDAAghdfaVVGSSPETLVKVTDGRVLTYPIAGSRPRG 342
Cdd:PRK13567 222 VVPSRIYKYAHHASqhlnQLsfQLYQNLKRQNPSPYMYYLNIDQPY-----IVGSSPESFVSVKDQIVTTNPIAGTIQRG 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 343 AGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAA 422
Cdd:PRK13567 297 ETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVSKIGTSKITKLMVIEKYEHVMHIVSEVTGKINQNLSPMTVIAN 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 423 TFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAES 502
Cdd:PRK13567 377 LLPTGTVSGAPKLRAIERIYEQYPHKRGVYSGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPEKELNET 456
|
...
gi 2541321043 503 RNK 505
Cdd:PRK13567 457 KLK 459
|
|
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
64-505 |
1.32e-74 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 243.29 E-value: 1.32e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 64 PGTFILESAEVDGTWARYSFVGVRSRATLTVAdGEATWTGDVPVGVPVTGDVLEVLGETLEVLR-TPAIAGLPPLTGGLV 142
Cdd:PRK15465 29 PWAMLLHSGYADHPYSRFDIVVADPICTLTTF-GKETVVSESEKRTTTTDDPLQVLQQVLDRADiRPTHNEDLPFQGGAL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 143 GAMGWDVVRHWEpTLPAKAPDELGVPELTLCLATDLAVVDHVDGSVWLVAnainfdatdervdeaHADAVARLDAMQTAl 222
Cdd:PRK15465 108 GLFGYDLGRRFE-SLPEIAEQDIVLPDMAVGIYDWALIVDHQRQTVSLLS---------------HNDVNARRAWLESQ- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 223 AAPVHVPPAVLGAgpepeleFRS--TRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLDVYRVLRTINPSPYMY 300
Cdd:PRK15465 171 QFSPQEDFTLTSD-------WQSnmTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 301 CFQLQDAAghdfaVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVC 380
Cdd:PRK15465 244 FLRLEQGA-----ILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 381 VPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFD 460
Cdd:PRK15465 319 VAGSVKVPELFVVEPFPAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLS 398
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 2541321043 461 FAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK15465 399 FCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDK 443
|
|
| MenF |
COG1169 |
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ... |
239-505 |
1.61e-69 |
|
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440783 [Multi-domain] Cd Length: 353 Bit Score: 226.57 E-value: 1.61e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 239 PELEFRSTR------QEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPAsPLDVYRV---LRTINPSPYMYCFQLqdAAG 309
Cdd:COG1169 74 PRLLLRRSRrgvpdpAEWREAVAQALEAIRAGELDKVVLARALDLTLDE-PIDPRALlarLRRRNPDCYTFAVEL--GAG 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 310 HDFavVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCvpTSVEVVE 389
Cdd:COG1169 151 DGF--VGASPERLVRRRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREALAPLC--SSLDVPE 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 390 LMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAI 469
Cdd:COG1169 227 EPELLRLRNVQHLATPITGTLDPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAV 306
|
250 260 270
....*....|....*....|....*....|....*.
gi 2541321043 470 AIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:COG1169 307 AIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAK 342
|
|
| PRK13566 |
PRK13566 |
anthranilate synthase component I; |
140-505 |
6.00e-62 |
|
anthranilate synthase component I;
Pssm-ID: 237429 [Multi-domain] Cd Length: 720 Bit Score: 215.94 E-value: 6.00e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 140 GLVGAMGWDVVRHWEPtLPAKAPDELGVPELTLCLATDLAVVDHVDGSVWLvanainfDATDERVDEAHADAVARldamQ 219
Cdd:PRK13566 156 GLYGAFGYDLAFQFEP-IEQKLPRPDDQRDLVLYLPDEILVVDHYAARAWV-------DRYEFAVGGVSTEGLPR----E 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 220 TALAAPVHVPPAVLGAGPEPElefrstrqEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLDVYRVLRTINPSPYM 299
Cdd:PRK13566 224 TAPSPYKPTTARPGFADHAPG--------EYAALVEKAKESFRRGDLFEVVPGQTFYEPCERSPSEIFRRLKEINPSPYG 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 300 YCFQLqdaaGHDFAVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKV 379
Cdd:PRK13566 296 FFINL----GDGEYLVGASPEMFVRVEGRRVETCPISGTIKRGADAIGDAEQIRKLLNSKKDESELTMCTDVDRNDKSRV 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 380 CVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYF 459
Cdd:PRK13566 372 CEPGSVKVIGRRQIEMYSRLIHTVDHVEGRLRPGFDALDAFLTHAWAVTVTGAPKLWAMQFIEDHERSPRRWYGGAVGMV 451
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 2541321043 460 DFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK13566 452 GFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFDSDPEAEEAETELK 497
|
|
| PRK07508 |
PRK07508 |
aminodeoxychorismate synthase component I; |
224-501 |
4.82e-58 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236035 [Multi-domain] Cd Length: 378 Bit Score: 197.54 E-value: 4.82e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 224 APVHVPPAVLGAGPEPELEFRS--TRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLDVYRVLRTINPSPY-MY 300
Cdd:PRK07508 86 SPEAPAPARPSENAARLRDPVArwDFADYAQRFERLHRHIRAGDCYQANLTFPLDARWGGDPLALFWALAARQPVGYgAL 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 301 CfqlqDAAGhdFAVVGSSPETLVKV-TDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKV 379
Cdd:PRK07508 166 V----DLGG--PVILSRSPELFFRVdGEGWIETHPMKGTAPRGATPAEDARLRAALLNDEKNQAENRMIVDLLRNDISRI 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 380 CVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYF 459
Cdd:PRK07508 240 SEVGSLDVPELFDIETYPTVHQMVSRVRARLLPGLGLADIFAALFPCGSITGAPKIRAMEILRELEPGPRDLYCGAIGWI 319
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 2541321043 460 DFAGDMDMAIAIRT-ALIRDGRASVQAGGGIVADSVEALEYAE 501
Cdd:PRK07508 320 APDGRMRFNVAIRTlSLFPGGRAVFNVGGGIVFDSTAEAEYEE 362
|
|
| PLN02889 |
PLN02889 |
oxo-acid-lyase/anthranilate synthase |
66-501 |
5.98e-55 |
|
oxo-acid-lyase/anthranilate synthase
Pssm-ID: 215481 [Multi-domain] Cd Length: 918 Bit Score: 198.92 E-value: 5.98e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 66 TFILESAEVDGTWARYSFVG---------------------VRSRATLTVADGEATWTGdvpvgVPVTGDVLEVLGETLE 124
Cdd:PLN02889 448 TFWLDSSSTEKKRGRFSFMGgkggslwkqmtfrlshqsdmdSKGGGHLSIEDSQGSIES-----TFLEKGFLDFLNKELL 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 125 VLR--TPAIAGLP-PLTGGLVGAMGWDVV--------RHweptlPAKAPDElgvpeltlCL--ATDLAVVDHVDGSVWLV 191
Cdd:PLN02889 523 SIRydEKDFEGLPfDFHGGYVGYIGYDLKvecgmasnRH-----KSTTPDA--------CFffADNVVVIDHHYDDVYIL 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 192 -------ANAINFDATDERVDEAHADAVARLD--AMQTALAAPVHvppavlgAGPEPElefrSTRQEFEEAVRAGKEAIR 262
Cdd:PLN02889 590 slhegstATTQWLDDTEQKLLGLKASATRKLEvqTSPTATFSPSK-------AGFLAD----KSREQYIKDVQKCLKYIK 658
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 263 DGEVFQVVLSQRL-----DLDcpasPLDVYRVLRTINPSPYMYCFQLQDAaghDFAVVGSSPETLVKVT-DGRVLTYPIA 336
Cdd:PLN02889 659 DGESYELCLTTQMrkrigEID----SLGLYLHLREKNPAPYAAWLNFSNE---NLCICSSSPERFLKLDrNGMLEAKPIK 731
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 337 GSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATA 416
Cdd:PLN02889 732 GTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLGRVCEPGSVHVPNLMDVESYTTVHTMVSTIRGKKRSNMSP 811
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 417 LQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEA 496
Cdd:PLN02889 812 VDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFFSYNQTFDLNIVIRTVVIHEGEASIGAGGAIVALSNPE 891
|
....*
gi 2541321043 497 LEYAE 501
Cdd:PLN02889 892 DEYEE 896
|
|
| PRK06404 |
PRK06404 |
anthranilate synthase component I; Reviewed |
259-505 |
4.11e-50 |
|
anthranilate synthase component I; Reviewed
Pssm-ID: 102361 [Multi-domain] Cd Length: 351 Bit Score: 175.44 E-value: 4.11e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 259 EAIRDGEVFQVVLSQRLDLDcpaspLDVYRVLR---TINPSPYMYCFQLQDaaghdFAVVGSSPETLVKVTDGRVLTYPI 335
Cdd:PRK06404 116 ELIRAGEVLQVVISREFEAN-----IDFKEKLSefiNNDRSRYVFYYRFGK-----YRVVGSSPENVFTVNGNIINVDPI 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 336 AGSRPrgagpeeDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLrPGAT 415
Cdd:PRK06404 186 AGTYD-------DKILSNELLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVMKIEEFSSVKHLVSQVTAKF-SNAS 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 416 ALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDfAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVE 495
Cdd:PRK06404 258 YRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGIIS-KGYTDMALVIRTAYSHGNGFRVRAGAGIVKDSDP 336
|
250
....*....|
gi 2541321043 496 ALEYAESRNK 505
Cdd:PRK06404 337 EDEVNEIYSK 346
|
|
| PRK05877 |
PRK05877 |
aminodeoxychorismate synthase component I; Provisional |
221-505 |
1.82e-49 |
|
aminodeoxychorismate synthase component I; Provisional
Pssm-ID: 235634 [Multi-domain] Cd Length: 405 Bit Score: 175.28 E-value: 1.82e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 221 ALAAPVHVPPAVLGAGPEPelefrSTRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLDVY-RVLRTINPSPYM 299
Cdd:PRK05877 120 ALATTRARPAPPCRIDWTP-----PDRAAHRDGVLACLEAIAAGEVYQACVCTQFTGTVTGSPLDFFaDGVARTAPARAA 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 300 YcfqlqdAAGHDFAVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEdaalaeeLLADPKERAEHIMLVDLSRNDLVKV 379
Cdd:PRK05877 195 Y------LAGDWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDADPSA-------LRASAKDVAENIMIVDLVRNDLGRV 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 380 CVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYF 459
Cdd:PRK05877 262 ARTGTVTVPELLVVRPAPGVWHLVSTVSAQVPDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLA 341
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2541321043 460 DFAGDMDMAIAIRTALI-RDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK05877 342 SPVAGCELNVAIRTVEFdADGNAVLGVGGGITADSDPDAEWQECLHK 388
|
|
| PRK07054 |
PRK07054 |
isochorismate synthase; |
202-502 |
4.09e-43 |
|
isochorismate synthase;
Pssm-ID: 235920 [Multi-domain] Cd Length: 475 Bit Score: 159.54 E-value: 4.09e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 202 ERVDEAHADAVA---RLDAMQTALAAPVhvPPAVLGAGPEPELEFRStRQEFEEAVRAGKEAIRDGEVFQVVL--SQRLD 276
Cdd:PRK07054 149 QHLVAAHDDPAAlagACCARIERLARPA--PAADDDAPRLLRASALQ-AREWQHEVRRAVDAIRGGAFGKVVLarDVLQQ 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 277 LDCPASPLDVYRVLRTINPSPYMYCFQLQDAAghdfaVVGSSPETLVKVTDGRVLTYPIAGSRPRGAGPEEDAALAEELL 356
Cdd:PRK07054 226 YARPVAIGPLLRRLRLRDPHAHLFAFRRGNAC-----FLGATPERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALM 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 357 ADPKERAEHIMLVDLSRNDLVKVCVptSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPR 436
Cdd:PRK07054 301 ASAKDRLEHALVVDAIRAALAPLSR--ALDIPDQPSLHRLPRLQHLSTPIRATLAPDATLLQVVAALHPTPAVGGHPRAA 378
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2541321043 437 AIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAES 502
Cdd:PRK07054 379 ALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVADSEPASEYRET 444
|
|
| PRK06923 |
PRK06923 |
isochorismate synthase DhbC; Validated |
190-505 |
6.29e-39 |
|
isochorismate synthase DhbC; Validated
Pssm-ID: 235886 [Multi-domain] Cd Length: 399 Bit Score: 146.42 E-value: 6.29e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 190 LVANAINFDATDERV----DEAHADAVARLD---AMQTALAAPVHVPPAvlgagPEPElefrstrqEFEEAVRAGKEAIR 262
Cdd:PRK06923 70 IVVGALPFDRRKEVQlivpEYSRISERLQLDttnHLEINRNLTFEMTPV-----PDPE--------VYMNGVKQGIAKIQ 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 263 DGEVFQVVLSQRLDLDCPAsPLDVYRVLRTI---NPSPYMYCFQL-QDAAGHDFAVVGSSPETLVKVTDGRVLTYPIAGS 338
Cdd:PRK06923 137 DGDLKKIVLSRSLDVKSSE-KIDKQKLLRELaehNKHGYTFAVNLpKDENENSKTLIGASPELLVSRHGMQVISNPLAGS 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 339 RPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCvpTSVEVVELMAIKRFSHIMHICSTVVGRLR-PGATAL 417
Cdd:PRK06923 216 RPRSDDPVEDKRRAEELLSSPKDLHEHAVVVEAVAAALRPYC--HTLHVPEKPSVIHTEAMWHLSTEVKGELKdPNTSSL 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 418 QTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEAL 497
Cdd:PRK06923 294 ELAIALHPTPAVCGTPTEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPED 373
|
....*...
gi 2541321043 498 EYAESRNK 505
Cdd:PRK06923 374 ELAETSAK 381
|
|
| PabB-fungal |
TIGR01823 |
aminodeoxychorismate synthase, fungal clade; This model represents the fungal clade of a ... |
11-505 |
3.55e-37 |
|
aminodeoxychorismate synthase, fungal clade; This model represents the fungal clade of a para-aminobenzoate synthesis enzyme, aminodeoxychorismate synthase, which acts on chorismate in a pathway that yields PABA, a precursor of folate.
Pssm-ID: 273821 [Multi-domain] Cd Length: 742 Bit Score: 146.20 E-value: 3.55e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 11 RPDATD--LAWGATWPSLGTFRELArtrrvvpvvrrllADDVTPVGLYRTLAQGRPGTFILESAEVDGtwaRYSFVGVRS 88
Cdd:TIGR01823 232 RTDDRDpiYKVKEKYPSGTTYVKQF-------------EVSEDPKLTFEICNIIREPKFVMSSSVITG---RYSIIALPN 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 89 RATL-----------TVADGEATWTGDVPVGVPVTG--------DVLEVLGETLEVLRTPAIAGLPPLTGGLVGAMGWDV 149
Cdd:TIGR01823 296 SASQvfthygamlktTVHYWQDTEISYTRLKKCLSGvdsdldksQFWITLGKFMENKKIDNPHREIPFIGGLVGILGYEI 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 150 VRHWEPTLPAKA--PDELG--VPELTLCLATDLAVVDHVDGSVWLVANAINFDATDERVDEAhADAVARLDAMQTALAAP 225
Cdd:TIGR01823 376 GSDLSTQYIACGrcNDDENslVPDAKLVFINRSIVIDHKQGKLYVQSLDNTFPVALEWSGEL-RDSFVRKKNIKQSLSWP 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 226 VHVPpavlgagpepeLEFRS-----TRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPA---SPLDVYRVLRTINPSP 297
Cdd:TIGR01823 455 FYLP-----------EEIDFvitfpDKEDYAKAFKACQDYLHAGDSYEMCLTTQTKVVPPAvisPDWEIYQRLRQRNPAP 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 298 YMYCFQLQDaaghdFAVVGSSPETLVKV-TDGRVLTYPIAGSRPRGagPEEDAALAEELLADPKERAEHIMLVDLSRNDL 376
Cdd:TIGR01823 524 FSGFFRLKH-----IIFLSTSPEKFLEVgMDTHAKLRPIKGTVKKG--PQMNLEKARRILKTPKEMGENLMILDLIRNDL 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 377 VKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGAT------ALQTLAATFPAGTLSGAPKPRAIALIDELEPARRG 450
Cdd:TIGR01823 597 YELVPKNDVHVEELMSVEEHATVYQLVSVVKAHGLTSASkktrysGIDVLKHSLPPGSMTGAPKKRSVQLLQDVEGGARG 676
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 2541321043 451 IYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQ--AGGGIVADSVEALEYAESRNK 505
Cdd:TIGR01823 677 IYSGVTGYWDVNGNGDFSVNIRCAFSYNGGTSWRigAGGAVTVLSTPEGELEEMYNK 733
|
|
| Anth_synt_I_N |
pfam04715 |
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) ... |
48-190 |
1.73e-33 |
|
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) catalyzes the first step in the biosynthesis of tryptophan. Component I catalyzes the formation of anthranilate using ammonia and chorismate. The catalytic site lies in the adjacent region, described in the chorismate binding enzyme family (pfam00425). This region is involved in feedback inhibition by tryptophan. This family also contains a region of Para-aminobenzoate synthase component I (EC 4.1.3.-).
Pssm-ID: 428082 [Multi-domain] Cd Length: 140 Bit Score: 123.96 E-value: 1.73e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 48 DDVTPVGLYRTLAqGRPGTFILESAEvdGTWARYSFVGVRSRATLTVADGEATWTGDVPVGVPVTGDVLEVLGETLEVLR 127
Cdd:pfam04715 1 DLLTPLSVYLKLA-GEPHSFLLESAE--GGEGRYSFIGINPLLTIKSKNGEVSVSGPDGQELEQEDGPLDALRALLARFR 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2541321043 128 -TPAIAGLPPLTGGLVGAMGWDVVRHWEPtLPAKAPDELGVPELTLCLATDLAVVDHVDGSVWL 190
Cdd:pfam04715 78 iEDSPPTLPPFSGGLVGYLGYDLVRYIEK-LPRTAPDDLNLPDARLILYEDLIVFDHQENKLYL 140
|
|
| PRK07912 |
PRK07912 |
salicylate synthase; |
205-505 |
6.40e-32 |
|
salicylate synthase;
Pssm-ID: 169151 [Multi-domain] Cd Length: 449 Bit Score: 127.99 E-value: 6.40e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 205 DEAHADAVARLdamqtaLAAPVHVPPAvlgagPEPeLEFRSTRQEFEEAVRAGKEAIRDGEVFQVVLSQRLDL----DCP 280
Cdd:PRK07912 153 GIRHREAIDRL------LATGVREVPQ-----SRS-VDVSDDPSGYRDRVAVAVAEIAAGRYHKVILSRCVEVpfavDFP 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 281 ASpldvYRVLRTINPSPYMYCFQLQDaaghdFAVVGSSPETLVKV-TDGRVLTYPIAGSRPRGAGPEEDAALAEELLADP 359
Cdd:PRK07912 221 AT----YRLGRRHNTPVRSFLLRLGG-----IRALGYSPELVTAVrADGVVITEPLAGTRAFGRGAAIDRLARDDLESNS 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 360 KERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQTLAATFPAGTLSGAPKPRAIA 439
Cdd:PRK07912 292 KEIVEHAISVRSSLAEITEIAEPGSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAAGVD 371
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2541321043 440 LIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK07912 372 AIFRLDEAPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEK 437
|
|
| PRK06772 |
PRK06772 |
salicylate synthase; |
251-505 |
1.56e-30 |
|
salicylate synthase;
Pssm-ID: 102546 [Multi-domain] Cd Length: 434 Bit Score: 123.69 E-value: 1.56e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 251 EEAVRAGKEaIRDGEVFQVVLSQRLDL----DCPASPLdvyrVLRTINPSPYMYCFQLQDAAGhdfavVGSSPETLVKVT 326
Cdd:PRK06772 177 QQVARAVAE-IRRGEYVKVIVSRAIPLpsriDMPATLL----YGRQANTPVRSFMFRQEGREA-----LGFSPELVMSVT 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 327 DGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHICSTV 406
Cdd:PRK06772 247 GNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGV 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 407 VGRLRPGATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDfAGDMDMAIAIRTALIRDGRASVQAG 486
Cdd:PRK06772 327 SGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLD-DTRFDAALVLRSVFQDSQRCWIQAG 405
|
250
....*....|....*....
gi 2541321043 487 GGIVADSVEALEYAESRNK 505
Cdd:PRK06772 406 AGIIAQSTPERELTETREK 424
|
|
| PRK07093 |
PRK07093 |
para-aminobenzoate synthase component I; Validated |
318-505 |
2.65e-30 |
|
para-aminobenzoate synthase component I; Validated
Pssm-ID: 235932 [Multi-domain] Cd Length: 323 Bit Score: 120.74 E-value: 2.65e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 318 SPETLVKVTDGRVLTYPIAGSRprgagpeeDAAL---AEELLADPKERAEHIMLVDLSRNDLVKVCvpTSVEVvelmaiK 394
Cdd:PRK07093 132 SPEPFVRIEDNKISTYPMKGTI--------DASLpnaEEKLLNDEKEFAEHATIVDLLRNDLSMVA--KNVRV------T 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 395 RFSHIMHI----------CSTVVGRLRPG--ATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDfA 462
Cdd:PRK07093 196 RFRYIDKIktnkgeilqtSSEISGTLPENwqENIGDILAKLLPAGSITGAPKEKTVEIIEQAEGYERGFYTGVFGYFD-G 274
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2541321043 463 GDMDMAIAIRTALIRDGRASVQAGGGIVADSVEALEYAESRNK 505
Cdd:PRK07093 275 ESLDSAVMIRFIEQENDGLYFKSGGGITIDSDLKDEYNELIQK 317
|
|
| PLN02786 |
PLN02786 |
isochorismate synthase |
262-501 |
2.55e-28 |
|
isochorismate synthase
Pssm-ID: 178383 [Multi-domain] Cd Length: 533 Bit Score: 118.35 E-value: 2.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 262 RDGEVFQVVL--SQRLDLDCPASPLDVYRVLRTINPSPYMYCFQLQDAAghdfAVVGSSPETLVKVTDGRVLTYPIAGSR 339
Cdd:PLN02786 276 KSSPLKKVVLarSSRIITDTDIDPIAWLACLQVEGQNAYQFCLQPPDAP----AFIGNTPEQLFHRKGLGVCSEALAATR 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 340 PRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCvpTSVEVVELMAIKRFSHIMHICSTVVGRLRPGATALQT 419
Cdd:PLN02786 352 PRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAIC--DRVVVEPHKAIRKLARVQHLYAQLAGRLRSEDDEFDI 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 420 LAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDfAGDMDMAIAIRTALIRDGR-ASVQAGGGIVADSVEALE 498
Cdd:PLN02786 430 LAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWFG-GGESEFAVGIRSALVEKGLgALIYAGTGIVEGSNPSSE 508
|
...
gi 2541321043 499 YAE 501
Cdd:PLN02786 509 WNE 511
|
|
| PRK15016 |
PRK15016 |
isochorismate synthase EntC; Provisional |
250-502 |
3.87e-20 |
|
isochorismate synthase EntC; Provisional
Pssm-ID: 184977 [Multi-domain] Cd Length: 391 Bit Score: 92.24 E-value: 3.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 250 FEEAVRAGKEAIRDGEVFQVVLSQRLDLDCPASPLDVYRVLRTI--NPSPYMYCFQLQDAAghdfAVVGSSPETLVKVTD 327
Cdd:PRK15016 129 FEAMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGALLERLIaqNPVSYNFHVPLADGG----VLLGASPELLLRKDG 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 328 GRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLV----KVCVPTSVEVVELmaikrfSHIMHIC 403
Cdd:PRK15016 205 ERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRerssELHVPSSPQLITT------PTLWHLA 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 404 STVVGRLRPGATALqTLAATF-PAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAGDMDMAIAIRTALIRDGRAS 482
Cdd:PRK15016 279 TPFEGKANAQENAL-TLACLLhPTPALSGFPHQAAKQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVR 357
|
250 260
....*....|....*....|
gi 2541321043 483 VQAGGGIVADSVEALEYAES 502
Cdd:PRK15016 358 LFAGAGIVPASSPLGEWRET 377
|
|
| PRK15012 |
PRK15012 |
menaquinone-specific isochorismate synthase; Provisional |
247-505 |
8.02e-12 |
|
menaquinone-specific isochorismate synthase; Provisional
Pssm-ID: 184974 [Multi-domain] Cd Length: 431 Bit Score: 67.18 E-value: 8.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 247 RQEFEEAVRAGKEAIRDGEVFQVVLSQRLDLDCpASPLDVYRVL---RTINPSPYMYCFqlqdAAGHDFAVVGSSPETLV 323
Cdd:PRK15012 169 KTGWTQLIELATKTIAEGELDKVVLARATDLHF-ASPVNAAAMMaasRRLNLNCYHFYM----AFDAENAFLGSSPERLW 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 324 KVTDGRVLTYPIAGSRPRGAGPEEDAALAEELLADPKERAEHIMLVDLSRNDLVKVCVPTSVEVVELMAIKRFSHIMHIC 403
Cdd:PRK15012 244 RRRDKALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCI 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541321043 404 STVVGRlrpgATALQTLAATFPAGTLSGAPKPRAIALIDELEPARRGIYGGTVGYFDFAgDMDMAIAIRTALIRDGRASV 483
Cdd:PRK15012 324 WTSLNK----ADDVICLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQ-QSEFCVSLRSAKVSGNVVRL 398
|
250 260
....*....|....*....|..
gi 2541321043 484 QAGGGIVADSVEALEYAESRNK 505
Cdd:PRK15012 399 YAGAGIVRGSDPEQEWQEIDNK 420
|
|
| |
