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Conserved domains on  [gi|2520696871|ref|WP_285612826|]
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class I SAM-dependent methyltransferase [Actinokineospora globicatena]

Protein Classification

class I SAM-dependent DNA methyltransferase( domain architecture ID 11471966)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:1904047
PubMed:  23180741|12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
6-164 1.02e-25

Predicted methyltransferase, contains TPR repeat [General function prediction only];


:

Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 96.99  E-value: 1.02e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871   6 EDYQRRFDTLAESGQDVHGEAVFV-------LGYRPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAPQV 78
Cdd:COG4976    12 DQYADSYDAALVEDLGYEAPALLAeellarlPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYD 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  79 RWHCRDLVGLD-LGRDFDVVVMAGnvpLFTPPGTQAQLVAGVAGHVAPGGVLIagFSLDRGYTTADYDQH-------CAA 150
Cdd:COG4976    92 RLLVADLADLAePDGRFDLIVAAD---VLTYLGDLAAVFAGVARALKPGGLFI--FSVEDADGSGRYAHSldyvrdlLAA 166

                         170
                  ....*....|....
gi 2520696871 151 AGLTATERYATWAK 164
Cdd:COG4976   167 AGFEVPGLLVVARK 180
 
Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
6-164 1.02e-25

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 96.99  E-value: 1.02e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871   6 EDYQRRFDTLAESGQDVHGEAVFV-------LGYRPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAPQV 78
Cdd:COG4976    12 DQYADSYDAALVEDLGYEAPALLAeellarlPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYD 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  79 RWHCRDLVGLD-LGRDFDVVVMAGnvpLFTPPGTQAQLVAGVAGHVAPGGVLIagFSLDRGYTTADYDQH-------CAA 150
Cdd:COG4976    92 RLLVADLADLAePDGRFDLIVAAD---VLTYLGDLAAVFAGVARALKPGGLFI--FSVEDADGSGRYAHSldyvrdlLAA 166

                         170
                  ....*....|....
gi 2520696871 151 AGLTATERYATWAK 164
Cdd:COG4976   167 AGFEVPGLLVVARK 180
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 37-127 9.32e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 74.14  E-value: 9.32e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  37 VLDAGCGTGRVGIELARH-GVEVEGVDVDESMLAVAGERA----PQVRWHCRDLVGLDLGRD-FDVVVMAGNVPLFTPPG 110
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRgGARVTGVDLSPEMLERARERAaeagLNVEFVQGDAEDLPFPDGsFDLVVSSGVLHHLPDPD 80

                          90
                  ....*....|....*..
gi 2520696871 111 tQAQLVAGVAGHVAPGG 127
Cdd:pfam13649  81 -LEAALREIARVLKPGG 96
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 37-133 7.26e-12

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 58.98  E-value: 7.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  37 VLDAGCGTGRVGIELARH-GVEVEGVDVDESMLAVA-----GERAPQVRWHCRDLVGLDLGRD--FDVVVMagNVPLFTP 108
Cdd:cd02440     2 VLDLGCGTGALALALASGpGARVTGVDISPVALELArkaaaALLADNVEVLKGDAEELPPEADesFDVIIS--DPPLHHL 79

                          90       100
                  ....*....|....*....|....*
gi 2520696871 109 PGTQAQLVAGVAGHVAPGGVLIAGF 133
Cdd:cd02440    80 VEDLARFLEEARRLLKPGGVLVLTL 104
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 36-98 7.82e-12

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 61.39  E-value: 7.82e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2520696871  36 SVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAP------QVRWHCRDLVGLdLGRdFDVVV 98
Cdd:PRK07580   66 RILDAGCGVGSLSIPLARRGAKVVASDISPQMVEEARERAPeaglagNITFEVGDLESL-LGR-FDTVV 132
BchM-ChlM TIGR02021
magnesium protoporphyrin O-methyltransferase; This model represents the ...
 37-98 2.06e-09

magnesium protoporphyrin O-methyltransferase; This model represents the S-adenosylmethionine-dependent O-methyltransferase responsible for methylation of magnesium protoporphyrin IX. This step is essentiasl for the biosynthesis of both chlorophyll and bacteriochlorophyll. This model encompasses two closely related clades, from cyanobacteria (and plants) where it is called ChlM and other photosynthetic bacteria where it is known as BchM. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273930 [Multi-domain]  Cd Length: 219  Bit Score: 54.80  E-value: 2.06e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2520696871  37 VLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAP------QVRWHCRDLVGLDlGRdFDVVV 98
Cdd:TIGR02021  59 VLDAGCGTGLLSIELAKRGAIVKAVDISEQMVQMARNRAQgrdvagNVEFEVNDLLSLC-GE-FDIVV 124
 
Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
6-164 1.02e-25

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 96.99  E-value: 1.02e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871   6 EDYQRRFDTLAESGQDVHGEAVFV-------LGYRPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAPQV 78
Cdd:COG4976    12 DQYADSYDAALVEDLGYEAPALLAeellarlPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYD 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  79 RWHCRDLVGLD-LGRDFDVVVMAGnvpLFTPPGTQAQLVAGVAGHVAPGGVLIagFSLDRGYTTADYDQH-------CAA 150
Cdd:COG4976    92 RLLVADLADLAePDGRFDLIVAAD---VLTYLGDLAAVFAGVARALKPGGLFI--FSVEDADGSGRYAHSldyvrdlLAA 166

                         170
                  ....*....|....
gi 2520696871 151 AGLTATERYATWAK 164
Cdd:COG4976   167 AGFEVPGLLVVARK 180
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
33-133 1.06e-21

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 84.49  E-value: 1.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  33 RPGSVLDAGCGTGRVGIELARH--GVEVEGVDVDESMLAVAGERAPQVRWHCRDLVGLDLGRDFDVVVMAGnvpLFTPPG 110
Cdd:COG4106     1 PPRRVLDLGCGTGRLTALLAERfpGARVTGVDLSPEMLARARARLPNVRFVVADLRDLDPPEPFDLVVSNA---ALHWLP 77

                          90       100
                  ....*....|....*....|...
gi 2520696871 111 TQAQLVAGVAGHVAPGGVLIAGF 133
Cdd:COG4106    78 DHAALLARLAAALAPGGVLAVQV 100
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 33-133 1.93e-21

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 84.30  E-value: 1.93e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  33 RPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAPQ--VRWHCRDLVGLDLGRD-FDVVVMAGNVPLFTPP 109
Cdd:COG2227    24 AGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAElnVDFVQGDLEDLPLEDGsFDLVICSEVLEHLPDP 103

                          90       100
                  ....*....|....*....|....
gi 2520696871 110 gtqAQLVAGVAGHVAPGGVLIAGF 133
Cdd:COG2227   104 ---AALLRELARLLKPGGLLLLST 124
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 37-127 9.32e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 74.14  E-value: 9.32e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  37 VLDAGCGTGRVGIELARH-GVEVEGVDVDESMLAVAGERA----PQVRWHCRDLVGLDLGRD-FDVVVMAGNVPLFTPPG 110
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRgGARVTGVDLSPEMLERARERAaeagLNVEFVQGDAEDLPFPDGsFDLVVSSGVLHHLPDPD 80

                          90
                  ....*....|....*..
gi 2520696871 111 tQAQLVAGVAGHVAPGG 127
Cdd:pfam13649  81 -LEAALREIARVLKPGG 96
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 12-154 1.96e-17

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 74.65  E-value: 1.96e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  12 FDTLAESgQDVHGEAVFVLGYRPGS-VLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAP----QVRWHCRDLV 86
Cdd:COG2226     1 FDRVAAR-YDGREALLAALGLRPGArVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAeaglNVEFVVGDAE 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  87 GLDLGRD-FDVVVMAGNVPLFTPPgtqAQLVAGVAGHVAPGGVL-IAGFSLDrgyTTADYDQHCAAAGLT 154
Cdd:COG2226    80 DLPFPDGsFDLVISSFVLHHLPDP---ERALAEIARVLKPGGRLvVVDFSPP---DLAELEELLAEAGFE 143
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 8-167 1.60e-15

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 70.72  E-value: 1.60e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871   8 YQRRFDTLAESGQDVHGEAVFVLGyRPGSVLDAGCGTGRVGIELA-RHGVEVEGVDVDESMLAVAGERAPQ-----VRWH 81
Cdd:COG0500     2 WDSYYSDELLPGLAALLALLERLP-KGGRVLDLGCGTGRNLLALAaRFGGRVIGIDLSPEAIALARARAAKaglgnVEFL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  82 CRDLVGLD--LGRDFDVVVMAGnVPLFTPPGTQAQLVAGVAGHVAPGGVLIAGfsldrGYTTADYDQHCAAAGLTATERY 159
Cdd:COG0500    81 VADLAELDplPAESFDLVVAFG-VLHHLPPEEREALLRELARALKPGGVLLLS-----ASDAAAALSLARLLLLATASLL 154


                  ....*...
gi 2520696871 160 ATWAKDPF 167
Cdd:COG0500   155 ELLLLLRL 162
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 1-130 2.30e-14

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 66.88  E-value: 2.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871   1 MTWNGEDYQRRFDTLAESGQDVHGEAVFVLGYRPGS-VLDAGCGTGRVGIELARH-GVEVEGVDVDESMLAVAGERA--- 75
Cdd:COG2230    18 MTYSCAYFEDPDDTLEEAQEAKLDLILRKLGLKPGMrVLDIGCGWGGLALYLARRyGVRVTGVTLSPEQLEYARERAaea 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  76 ---PQVRWHCRDLVGLDLGRDFDVVVMAGnvpLFT--PPGTQAQLVAGVAGHVAPGGVLI 130
Cdd:COG2230    98 glaDRVEVRLADYRDLPADGQFDAIVSIG---MFEhvGPENYPAYFAKVARLLKPGGRLL 154
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 37-133 7.26e-12

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 58.98  E-value: 7.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  37 VLDAGCGTGRVGIELARH-GVEVEGVDVDESMLAVA-----GERAPQVRWHCRDLVGLDLGRD--FDVVVMagNVPLFTP 108
Cdd:cd02440     2 VLDLGCGTGALALALASGpGARVTGVDISPVALELArkaaaALLADNVEVLKGDAEELPPEADesFDVIIS--DPPLHHL 79

                          90       100
                  ....*....|....*....|....*
gi 2520696871 109 PGTQAQLVAGVAGHVAPGGVLIAGF 133
Cdd:cd02440    80 VEDLARFLEEARRLLKPGGVLVLTL 104
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 36-98 7.82e-12

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 61.39  E-value: 7.82e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2520696871  36 SVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAP------QVRWHCRDLVGLdLGRdFDVVV 98
Cdd:PRK07580   66 RILDAGCGVGSLSIPLARRGAKVVASDISPQMVEEARERAPeaglagNITFEVGDLESL-LGR-FDTVV 132
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 38-130 1.43e-10

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 55.36  E-value: 1.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  38 LDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAPQVRWHCRDLVGLDLG-RD--FDVVVMAGNVPLFTPPgtqAQ 114
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLTFVVGDAEDLPfPDnsFDLVLSSEVLHHVEDP---ER 77

                          90
                  ....*....|....*.
gi 2520696871 115 LVAGVAGHVAPGGVLI 130
Cdd:pfam08241  78 ALREIARVLKPGGILI 93
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 38-129 1.43e-10

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 55.45  E-value: 1.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  38 LDAGCGTGRVGIELARH--GVEVEGVDVDESMLAVAGERAPQVRWHCRDLVGLD-------LGRDFDVVVMAgNVPLFTP 108
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAlpGLEYTGLDISPAALEAARERLAALGLLNAVRVELFqldlgelDPGSFDVVVAS-NVLHHLA 79

                          90       100
                  ....*....|....*....|.
gi 2520696871 109 pgTQAQLVAGVAGHVAPGGVL 129
Cdd:pfam08242  80 --DPRAVLRNIRRLLKPGGVL 98
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
26-104 1.90e-09

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 54.52  E-value: 1.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  26 AVFVLGYRPGS-VLDAGCGTGRVGIELARHGVE-VEGVDVDESMLAVAGERAPQ----VRWHCRDLVGLDLGRDFDVVVM 99
Cdd:COG2263    37 LAYLRGDIEGKtVLDLGCGTGMLAIGAALLGAKkVVGVDIDPEALEIARENAERlgvrVDFIRADVTRIPLGGSVDTVVM 116


                  ....*
gi 2520696871 100 agNVP 104
Cdd:COG2263   117 --NPP 119
BchM-ChlM TIGR02021
magnesium protoporphyrin O-methyltransferase; This model represents the ...
 37-98 2.06e-09

magnesium protoporphyrin O-methyltransferase; This model represents the S-adenosylmethionine-dependent O-methyltransferase responsible for methylation of magnesium protoporphyrin IX. This step is essentiasl for the biosynthesis of both chlorophyll and bacteriochlorophyll. This model encompasses two closely related clades, from cyanobacteria (and plants) where it is called ChlM and other photosynthetic bacteria where it is known as BchM. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273930 [Multi-domain]  Cd Length: 219  Bit Score: 54.80  E-value: 2.06e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2520696871  37 VLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAP------QVRWHCRDLVGLDlGRdFDVVV 98
Cdd:TIGR02021  59 VLDAGCGTGLLSIELAKRGAIVKAVDISEQMVQMARNRAQgrdvagNVEFEVNDLLSLC-GE-FDIVV 124
PRK08317 PRK08317
hypothetical protein; Provisional
 30-98 5.23e-08

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 50.71  E-value: 5.23e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2520696871  30 LGYRPG-SVLDAGCGTGRVGIELARH---GVEVEGVDVDESMLAVAGERA----PQVRWHCRDLVGLDLGRD-FDVVV 98
Cdd:PRK08317   15 LAVQPGdRVLDVGCGPGNDARELARRvgpEGRVVGIDRSEAMLALAKERAaglgPNVEFVRGDADGLPFPDGsFDAVR 92
PRK11207 PRK11207
tellurite resistance methyltransferase TehB;
23-127 6.60e-08

tellurite resistance methyltransferase TehB;


Pssm-ID: 183040  Cd Length: 197  Bit Score: 50.12  E-value: 6.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  23 HGEAVFVLGY-RPGSVLDAGCGTGRVGIELARHGVEVEGVDVD-------ESMLAVAGERAPQVRWHcrDLVGLDLGRDF 94
Cdd:PRK11207   19 HSEVLEAVKVvKPGKTLDLGCGNGRNSLYLAANGFDVTAWDKNpmsianlERIKAAENLDNLHTAVV--DLNNLTFDGEY 96

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2520696871  95 DvVVMAGNVPLFTPPGTQAQLVAGVAGHVAPGG 127
Cdd:PRK11207   97 D-FILSTVVLMFLEAKTIPGLIANMQRCTKPGG 128
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 33-130 1.05e-06

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 47.45  E-value: 1.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  33 RPGSVLDAGCGTGRVGIELARH--GVEVEGVDVDESMLAVAGERA------PQVRWHCRDLV-GLDLGRDFDVVV----- 98
Cdd:COG2890   112 APPRVLDLGTGSGAIALALAKErpDARVTAVDISPDALAVARRNAerlgleDRVRFLQGDLFePLPGDGRFDLIVsnppy 191

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2520696871  99 --------MAGNVPLFTP-----PGTQ-----AQLVAGVAGHVAPGGVLI 130
Cdd:COG2890   192 ipedeialLPPEVRDHEPrlaldGGEDgldfyRRIIAQAPRLLKPGGWLL 241
Nnt1 COG3897
Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, ...
 37-131 1.55e-06

Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443104 [Multi-domain]  Cd Length: 216  Bit Score: 46.42  E-value: 1.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  37 VLDAGCGTGRVGIELARHG-VEVEGVDVDESMLAVAGERAP----QVRWHCRDLVGLDLGRDFDVVVmAGNVpLFTPPgT 111
Cdd:COG3897    74 VLELGCGLGLVGIAAAKAGaADVTATDYDPEALAALRLNAAlngvAITTRLGDWRDPPAAGGFDLIL-GGDV-LYERD-L 150

                          90       100
                  ....*....|....*....|.
gi 2520696871 112 QAQLVAGVAGHVAPGG-VLIA 131
Cdd:COG3897   151 AEPLLPFLDRLAAPGGeVLIG 171
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 33-130 2.24e-06

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 45.50  E-value: 2.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  33 RPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAPQVrWHCRDLVGLDLGRdFDVVVMA---GNVPlfTPP 109
Cdd:pfam13489  22 SPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSPIAIERALLNVRFD-QFDEQEAAVPAGK-FDVIVARevlEHVP--DPP 97

                          90       100
                  ....*....|....*....|.
gi 2520696871 110 GTQAQLVAgvagHVAPGGVLI 130
Cdd:pfam13489  98 ALLRQIAA----LLKPGGLLL 114
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 34-129 2.53e-06

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 45.57  E-value: 2.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  34 PGSVLDAGCGTGRVGIELARH--GVEVEGVDVDESMLAVA-------GERAPQVRWH-CRDLVGldlGRDFDVVVMagNV 103
Cdd:COG2813    50 GGRVLDLGCGYGVIGLALAKRnpEARVTLVDVNARAVELAranaaanGLENVEVLWSdGLSGVP---DGSFDLILS--NP 124

                          90       100       110
                  ....*....|....*....|....*....|
gi 2520696871 104 P----LFTPPGTQAQLVAGVAGHVAPGGVL 129
Cdd:COG2813   125 PfhagRAVDKEVAHALIADAARHLRPGGEL 154
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 30-104 2.70e-06

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 45.91  E-value: 2.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  30 LGYRPGS-VLDAGCGTGRVGIELARHG---VEVEGVDVDESMLAVAGERA------PQVRWHCRDlvGLDLGRD---FDV 96
Cdd:PRK00216   47 LGVRPGDkVLDLACGTGDLAIALAKAVgktGEVVGLDFSEGMLAVGREKLrdlglsGNVEFVQGD--AEALPFPdnsFDA 124

                          90
                  ....*....|.
gi 2520696871  97 VVMA-G--NVP 104
Cdd:PRK00216  125 VTIAfGlrNVP 135
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 36-99 3.84e-06

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 45.94  E-value: 3.84e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2520696871  36 SVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERA-----PQVRWHCRD----LVGLDLGRDFDVVVM 99
Cdd:COG2265   236 RVLDLYCGVGTFALPLARRAKKVIGVEIVPEAVEDARENArlnglKNVEFVAGDleevLPELLWGGRPDVVVL 308
PRK14968 PRK14968
putative methyltransferase; Provisional
 13-109 6.60e-06

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 44.50  E-value: 6.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  13 DT--LAESGQDVHGEavfvlgyrpgSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAPQVRWHCRDLVGL-- 88
Cdd:PRK14968   11 DSflLAENAVDKKGD----------RVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNNGVEVIrs 80

                          90       100
                  ....*....|....*....|....*.
gi 2520696871  89 DL-----GRDFDVVvmagnvpLFTPP 109
Cdd:PRK14968   81 DLfepfrGDKFDVI-------LFNPP 99
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 34-134 1.33e-05

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 43.81  E-value: 1.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  34 PGSVLDAGCGTGRVGIELARHG--VEVEGVDVDESMLAVAGER-APQVRWHCRDLVGLDL-GRDFDVVVMAGNVPLFTPP 109
Cdd:TIGR02072  35 PASVLDIGCGTGYLTRALLKRFpqAEFIALDISAGMLAQAKTKlSENVQFICGDAEKLPLeDSSFDLIVSNLALQWCDDL 114

                          90       100
                  ....*....|....*....|....*
gi 2520696871 110 gtqAQLVAGVAGHVAPGGVLIagFS 134
Cdd:TIGR02072 115 ---SQALSELARVLKPGGLLA--FS 134
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 35-130 1.59e-05

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 42.96  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  35 GSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERAP---------QVRWhcRDLVGLDLGRDFDVVVMagNVP- 104
Cdd:pfam05175  33 GKVLDLGCGAGVLGAALAKESPDAELTMVDINARALESARENlaanglengEVVA--SDVYSGVEDGKFDLIIS--NPPf 108

                          90       100
                  ....*....|....*....|....*....
gi 2520696871 105 ---LFTPPGTQAQLVAGVAGHVAPGGVLI 130
Cdd:pfam05175 109 hagLATTYNVAQRFIADAKRHLRPGGELW 137
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 33-129 1.75e-05

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 43.59  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  33 RPGSVLDAGCGTGRVGIELAR--HGVEVEGVDVDESMLAVAGER------APQVRWHCRDL--VGLDLGRD-FDVVVMag 101
Cdd:COG4123    37 KGGRVLDLGTGTGVIALMLAQrsPGARITGVEIQPEAAELARRNvalnglEDRITVIHGDLkeFAAELPPGsFDLVVS-- 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2520696871 102 NVPLFTPP------------------GTQAQLVAGVAGHVAPGGVL 129
Cdd:COG4123   115 NPPYFKAGsgrkspdearaiarhedaLTLEDLIRAAARLLKPGGRF 160
PLN02585 PLN02585
magnesium protoporphyrin IX methyltransferase
 36-75 1.94e-05

magnesium protoporphyrin IX methyltransferase


Pssm-ID: 215319 [Multi-domain]  Cd Length: 315  Bit Score: 43.69  E-value: 1.94e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2520696871  36 SVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERA 75
Cdd:PLN02585  147 TVCDAGCGTGSLAIPLALEGAIVSASDISAAMVAEAERRA 186
PRK06202 PRK06202
hypothetical protein; Provisional
 33-98 2.30e-05

hypothetical protein; Provisional


Pssm-ID: 180466 [Multi-domain]  Cd Length: 232  Bit Score: 43.07  E-value: 2.30e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2520696871  33 RPGSVLDAGCGTGRVGIELARHG------VEVEGVDVDESMLAVAGERA--PQVRW---HCRDLVglDLGRDFDVVV 98
Cdd:PRK06202   60 RPLTLLDIGCGGGDLAIDLARWArrdglrLEVTAIDPDPRAVAFARANPrrPGVTFrqaVSDELV--AEGERFDVVT 134
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 37-75 2.95e-05

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 42.02  E-value: 2.95e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2520696871  37 VLDAGCGTGRVGIELA---RHGVEVEGVDVDESMLAVAGERA 75
Cdd:pfam13847   7 VLDLGCGTGHLSFELAeelGPNAEVVGIDISEEAIEKARENA 48
TehB pfam03848
Tellurite resistance protein TehB;
6-136 4.46e-05

Tellurite resistance protein TehB;


Pssm-ID: 397776  Cd Length: 193  Bit Score: 42.14  E-value: 4.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871   6 EDY-QRRFDTLAESGQDVhgEAVFVLgyRPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLA-----VAGERAPQVR 79
Cdd:pfam03848   6 EDYfHKKYNLTPTHSEVL--EAVKIV--KPGKVLDLGCGQGRNSLYLSLLGYDVTAWDKNENSIAnlqriKEKENLDNIH 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2520696871  80 WHCRDLVGLDLGRDFDVVVmAGNVPLFTPPGTQAQLVAGVAGHVAPGG--VLIAGFSLD 136
Cdd:pfam03848  82 TALYDINNATIDENYDFIL-STVVLMFLEPERIPGIIANMQECTNPGGynLIVAAMSTD 139
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 30-130 4.66e-05

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 42.46  E-value: 4.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  30 LGYRPGSVLDAGCGTGRVGIELARH--GVEVEGVDVDESMLAVAGERA-----PQVRWHCRDLV-GLDLGRdFDVVV--- 98
Cdd:PRK09328  105 LLKEPLRVLDLGTGSGAIALALAKErpDAEVTAVDISPEALAVARRNAkhglgARVEFLQGDWFePLPGGR-FDLIVsnp 183

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2520696871  99 ----------MAGNVPLFTPP--------GTQA--QLVAGVAGHVAPGGVLI 130
Cdd:PRK09328  184 pyipeadihlLQPEVRDHEPHlalfggedGLDFyrRIIEQAPRYLKPGGWLL 235
Rsm22 COG5459
Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal ...
 29-130 4.99e-05

Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal structure and biogenesis]; Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 444210 [Multi-domain]  Cd Length: 306  Bit Score: 42.64  E-value: 4.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  29 VLGYRPGSVLDAGCGTGRVGIELAR---HGVEVEGVDVDESMLAV--------AGERAPQVRWHCRDLVGLDLGRDFDVV 97
Cdd:COG5459    76 GPDFAPLTVLDVGAGPGTAAWAAADawpSLLDATLLERSAAALALgrrlaraaANPALETAEWRLADLAAALPAPPADLV 155

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2520696871  98 VMAgNVPLFTPPGTQAQLVAgvAGHVAPGGVLI 130
Cdd:COG5459   156 VAS-YVLNELADAARAALVD--RLWLAPDGALL 185
PRK12335 PRK12335
tellurite resistance protein TehB; Provisional
 22-69 8.72e-05

tellurite resistance protein TehB; Provisional


Pssm-ID: 183450 [Multi-domain]  Cd Length: 287  Bit Score: 41.85  E-value: 8.72e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2520696871  22 VHGEAVFVLGY-RPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLA 69
Cdd:PRK12335  108 THSEVLEAVQTvKPGKALDLGCGQGRNSLYLALLGFDVTAVDINQQSLE 156
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
36-130 8.74e-05

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 41.68  E-value: 8.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  36 SVLDAGCGTGRVGIELARHGV-EVEGVDVDEsmLAV--AGERApqVRWHCRDLVGLDLG-RDFDVVVmagnvplftppgt 111
Cdd:PRK00517  122 TVLDVGCGSGILAIAAAKLGAkKVLAVDIDP--QAVeaARENA--ELNGVELNVYLPQGdLKADVIV------------- 184

                          90       100
                  ....*....|....*....|....*..
gi 2520696871 112 qAQLVAGV--------AGHVAPGGVLI 130
Cdd:PRK00517  185 -ANILANPllelapdlARLLKPGGRLI 210
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 33-73 3.91e-04

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 39.16  E-value: 3.91e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2520696871  33 RPGS-VLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGE 73
Cdd:COG1041    25 KEGDtVLDPFCGTGTILIEAGLLGRRVIGSDIDPKMVEGARE 66
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
33-97 7.36e-04

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 38.96  E-value: 7.36e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2520696871  33 RPGSVLDAGCGTGRVGIELARH---GVEVEGVDVDESMLAVAGERAP-----QVRWHCRDLVGLDLGRD-FDVV 97
Cdd:pfam01209  42 RGNKFLDVAGGTGDWTFGLSDSagsSGKVVGLDINENMLKEGEKKAKeegkyNIEFLQGNAEELPFEDDsFDIV 115
PRK11036 PRK11036
tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;
30-75 7.94e-04

tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;


Pssm-ID: 182918  Cd Length: 255  Bit Score: 38.79  E-value: 7.94e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2520696871  30 LGYRPGSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGERA 75
Cdd:PRK11036   41 LPPRPLRVLDAGGGEGQTAIKLAELGHQVILCDLSAEMIQRAKQAA 86
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 33-130 1.26e-03

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 38.40  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  33 RPG-SVLDAGCGTGRVGIELARHGV-EVEGVDVDESMLAVAGERAPqvRWHCRDLVGLDLGRD-----FDVVV---MAGN 102
Cdd:pfam06325 160 KPGeSVLDVGCGSGILAIAALKLGAkKVVGVDIDPVAVRAAKENAE--LNGVEARLEVYLPGDlpkekADVVVaniLADP 237

                          90       100
                  ....*....|....*....|....*...
gi 2520696871 103 VPLFTPPgtqaqlvagVAGHVAPGGVLI 130
Cdd:pfam06325 238 LIELAPD---------IYALVKPGGYLI 256
PRK14103 PRK14103
trans-aconitate 2-methyltransferase; Provisional
 33-129 1.57e-03

trans-aconitate 2-methyltransferase; Provisional


Pssm-ID: 184509  Cd Length: 255  Bit Score: 37.75  E-value: 1.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  33 RPGSVLDAGCGTGRVGIELARH--GVEVEGVDVDESMLAVAGERAPQVRwhCRDLVGLDLGRDFDVVVmaGNVPLFTPPG 110
Cdd:PRK14103   29 RARRVVDLGCGPGNLTRYLARRwpGAVIEALDSSPEMVAAARERGVDAR--TGDVRDWKPKPDTDVVV--SNAALQWVPE 104

                          90
                  ....*....|....*....
gi 2520696871 111 tQAQLVAGVAGHVAPGGVL 129
Cdd:PRK14103  105 -HADLLVRWVDELAPGSWI 122
PRK15001 PRK15001
23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG;
13-74 2.51e-03

23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG;


Pssm-ID: 184963 [Multi-domain]  Cd Length: 378  Bit Score: 37.70  E-value: 2.51e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2520696871  13 DTLAESGQDVHgeAVFVLGYRP----GSVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGER 74
Cdd:PRK15001  206 NVFSRTGLDIG--ARFFMQHLPenleGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSR 269
YtxK COG0827
Adenine-specific DNA N6-methylase [Replication, recombination and repair];
35-104 2.56e-03

Adenine-specific DNA N6-methylase [Replication, recombination and repair];


Pssm-ID: 440589 [Multi-domain]  Cd Length: 327  Bit Score: 37.62  E-value: 2.56e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2520696871  35 GSVLDAGCGTGRVGIELARH---GVEVEGVDVDESMLAVAGERAP----QVRWHCRDLVGLDLGRDFDVVVmaGNVP 104
Cdd:COG0827   117 LRILDPAVGTGNLLTTVLNQlkkKVNAYGVEVDDLLIRLAAVLANlqghPVELFHQDALQPLLIDPVDVVI--SDLP 191
RlmK COG1092
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ...
 36-137 2.76e-03

23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440709 [Multi-domain]  Cd Length: 392  Bit Score: 37.47  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  36 SVLDAGCGTGRVGIELARHG-VEVEGVDVDESMLAVAGERA------PQVRWHC-------RDLVglDLGRDFDVVVMag 101
Cdd:COG1092   219 RVLNLFSYTGGFSVHAAAGGaKSVTSVDLSATALEWAKENAalngldDRHEFVQadafdwlRELA--REGERFDLIIL-- 294

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2520696871 102 NVPLFTPpgTQAQLVAGVAGH----------VAPGGVLIA-----GFSLDR 137
Cdd:COG1092   295 DPPAFAK--SKKDLFDAQRDYkdlnrlalklLAPGGILVTsscsrHFSLDL 343
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
36-130 2.98e-03

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 37.07  E-value: 2.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  36 SVLDAGCGTGRVGIELARHGV-EVEGVDVDESMLAVAGERApqVRWHCRDLV------GLDLGRdFDVVV---MAGnvPL 105
Cdd:COG2264   151 TVLDVGCGSGILAIAAAKLGAkRVLAVDIDPVAVEAARENA--ELNGVEDRIevvlgdLLEDGP-YDLVVaniLAN--PL 225

                          90       100
                  ....*....|....*....|....*
gi 2520696871 106 ftppgtqAQLVAGVAGHVAPGGVLI 130
Cdd:COG2264   226 -------IELAPDLAALLKPGGYLI 243
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 27-131 4.73e-03

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 36.29  E-value: 4.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  27 VFVLGYRPGS-VLDAGCGTGRVGIELAR----HGvEVEGVDVDESMLAVAGE------RAPQVRWHCRDLV-GLDlGRDF 94
Cdd:COG2519    84 IARLDIFPGArVLEAGTGSGALTLALARavgpEG-KVYSYERREDFAEIARKnlerfgLPDNVELKLGDIReGID-EGDV 161

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2520696871  95 DVVVMagNVPlfTPPgtqaQLVAGVAGHVAPGGVLIA 131
Cdd:COG2519   162 DAVFL--DMP--DPW----EALEAVAKALKPGGVLVA 190
PRK10258 PRK10258
biotin biosynthesis protein BioC; Provisional
 36-74 7.02e-03

biotin biosynthesis protein BioC; Provisional


Pssm-ID: 182340 [Multi-domain]  Cd Length: 251  Bit Score: 35.89  E-value: 7.02e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2520696871  36 SVLDAGCGTGRVGIELARHGVEVEGVDVDESMLAVAGER 74
Cdd:PRK10258   45 HVLDAGCGPGWMSRYWRERGSQVTALDLSPPMLAQARQK 83
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 37-131 8.26e-03

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 35.45  E-value: 8.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520696871  37 VLDAGCGTG---RVgieLARHGVEVEGVDVDESMLAVAGER-----APQVRWHCRDLV-GLDLGRDFDVVVMAGNVPLFt 107
Cdd:COG2518    70 VLEIGTGSGyqaAV---LARLAGRVYSVERDPELAERARERlaalgYDNVTVRVGDGAlGWPEHAPFDRIIVTAAAPEV- 145

                          90       100
                  ....*....|....*....|....
gi 2520696871 108 PPGTQAQLvagvaghvAPGGVLIA 131
Cdd:COG2518   146 PEALLEQL--------APGGRLVA 161
PLN02336 PLN02336
phosphoethanolamine N-methyltransferase
 8-75 8.59e-03

phosphoethanolamine N-methyltransferase


Pssm-ID: 177970 [Multi-domain]  Cd Length: 475  Bit Score: 35.88  E-value: 8.59e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2520696871   8 YQRRFDT--LAESGQDVHGEAVFVLGYRPGS-VLDAGCGTGRVGIELA-RHGVEVEGVDVDESMLAVAGERA 75
Cdd:PLN02336  238 YERVFGEgfVSTGGLETTKEFVDKLDLKPGQkVLDVGCGIGGGDFYMAeNFDVHVVGIDLSVNMISFALERA 309
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
33-98 9.12e-03

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 35.40  E-value: 9.12e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2520696871  33 RPGS-VLDAGCGTGRVGIELARHGVE-VEGVDVDESMLAVAGERAPQ------VRWHCRDLVGLDLGRDFDVVV 98
Cdd:COG4076    34 KPGDvVLDIGTGSGLLSMLAARAGAKkVYAVEVNPDIAAVARRIIAAnglsdrITVINADATDLDLPEKADVII 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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