|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
1-444 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 928.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 1 MFTRVANFCRKVLSRDESMADDVIVQNTMSVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 80
Cdd:PRK11623 8 IFTRVANFCRKVLSREESEAEQAVARPQMTVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 81 FDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGTPSDRTTSQQGQNGMLLRDNIFGSIEEDAQR 160
Cdd:PRK11623 88 FDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESDRNTSQRGQNGMLLRDNIFGSIEEDAQR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 161 RDFTINSLYYSVADFTVRDFVGGVPDLKAGLIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLIND 240
Cdd:PRK11623 168 RDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLND 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 241 VPPARLFEEALKLLQAGHGFATYQLLREYSLFQPLFPTITRNFTEKGDSAMERIIDQVLKNTDNRIQNDMRVNPAFLFAA 320
Cdd:PRK11623 248 IPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 321 MFWYPLLETAQKIAQESGLAYYDAFALATNDVLDEACRSLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 400
Cdd:PRK11623 328 MFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 407
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2314193603 401 YDLMALRAEAENNRELQLLVQWWGEFQVSAPPAQKDMLGDLDED 444
Cdd:PRK11623 408 YDLLALRAEVENNAELQRLAQWWGEFQVSAPPQQKGMLNELDDD 451
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
31-437 |
5.57e-166 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 473.90 E-value: 5.57e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 31 VIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAH 110
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 111 VMFGPEIIEVATFRGHHEgtpsdrttSQQGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKAG 190
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGHK--------SSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 191 LIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGHGFATYQLLREYS 270
Cdd:TIGR01942 153 RLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 271 LFQPLFPTITRNFTEKGDSAMERIIDQVLKNTDNRIQNDMRVNPAFLFAAMFWYPLLETAQKIAQEsGLAYYDAFALATN 350
Cdd:TIGR01942 233 LLEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 351 DVLDEACRSLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDLMALRAEAenNRELQLLVQWWGEFQVSA 430
Cdd:TIGR01942 312 DFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVC--GRENAVLGEWWTPYQLAS 389
|
....*..
gi 2314193603 431 PPAQKDM 437
Cdd:TIGR01942 390 EEERTEM 396
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
43-427 |
5.15e-127 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 373.77 E-value: 5.15e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 43 DISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFR---NCRLVGRRFRLAHVMFGPEIIE 119
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 120 VATFRGHHEGTPSDRTtsqqgqngmllrDNIFG-SIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKAGLIRLIGNP 198
Cdd:COG0617 81 VATARTERYYGDGRRP------------FVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 199 ETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGHGFATYQLLREYSLFQPLfpt 278
Cdd:COG0617 149 EERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 279 itrnftekgdsameriidqvlkntdnriqndmrvnpAFLFAAMFwYPLLETAQKiaqESGLAYYDAFALATNDVLDEACR 358
Cdd:COG0617 226 ------------------------------------ALRLAALL-HDLGKPATR---EDGLPTFHGHEEAGAELAEALLK 265
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2314193603 359 SLAIPKRITTLVRDIWQLQLRMSRRQGKRAW---KLMEHpKFRAAYDLMALRAEAENNRELQ-----LLVQWWGEFQ 427
Cdd:COG0617 266 RLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQerlaeLLEAAWRRFQ 341
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
62-193 |
1.13e-48 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 162.83 E-value: 1.13e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 62 AYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLV----GRRFRLAHVMFGPEIIEVATFRGHHEgtPSDRTTS 137
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLFRRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEFD--ESDFRNP 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2314193603 138 QQGQNGmllrdnifGSIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKAGLIR 193
Cdd:pfam01743 79 RSEEYT--------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
45-189 |
2.16e-41 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 144.27 E-value: 2.16e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 45 SENALKVLYRLNKA-GYEAYLVGGGVRDLLLGKKPKDFDVTTSA-TPEQVRKLFR--NCRLVGR--RFRLAHVMFGPEII 118
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2314193603 119 EVATFRGHHEGTPSDRTTSqqgqngmllrdnIFGSIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKA 189
Cdd:cd05398 81 DVATLRTETYTDPGRRPPV------------VGFTIEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
1-444 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 928.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 1 MFTRVANFCRKVLSRDESMADDVIVQNTMSVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 80
Cdd:PRK11623 8 IFTRVANFCRKVLSREESEAEQAVARPQMTVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 81 FDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGTPSDRTTSQQGQNGMLLRDNIFGSIEEDAQR 160
Cdd:PRK11623 88 FDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESDRNTSQRGQNGMLLRDNIFGSIEEDAQR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 161 RDFTINSLYYSVADFTVRDFVGGVPDLKAGLIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLIND 240
Cdd:PRK11623 168 RDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLND 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 241 VPPARLFEEALKLLQAGHGFATYQLLREYSLFQPLFPTITRNFTEKGDSAMERIIDQVLKNTDNRIQNDMRVNPAFLFAA 320
Cdd:PRK11623 248 IPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 321 MFWYPLLETAQKIAQESGLAYYDAFALATNDVLDEACRSLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 400
Cdd:PRK11623 328 MFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 407
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2314193603 401 YDLMALRAEAENNRELQLLVQWWGEFQVSAPPAQKDMLGDLDED 444
Cdd:PRK11623 408 YDLLALRAEVENNAELQRLAQWWGEFQVSAPPQQKGMLNELDDD 451
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
31-437 |
5.57e-166 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 473.90 E-value: 5.57e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 31 VIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAH 110
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 111 VMFGPEIIEVATFRGHHEgtpsdrttSQQGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKAG 190
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGHK--------SSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 191 LIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGHGFATYQLLREYS 270
Cdd:TIGR01942 153 RLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 271 LFQPLFPTITRNFTEKGDSAMERIIDQVLKNTDNRIQNDMRVNPAFLFAAMFWYPLLETAQKIAQEsGLAYYDAFALATN 350
Cdd:TIGR01942 233 LLEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 351 DVLDEACRSLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDLMALRAEAenNRELQLLVQWWGEFQVSA 430
Cdd:TIGR01942 312 DFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVC--GRENAVLGEWWTPYQLAS 389
|
....*..
gi 2314193603 431 PPAQKDM 437
Cdd:TIGR01942 390 EEERTEM 396
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
43-427 |
5.15e-127 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 373.77 E-value: 5.15e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 43 DISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFR---NCRLVGRRFRLAHVMFGPEIIE 119
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 120 VATFRGHHEGTPSDRTtsqqgqngmllrDNIFG-SIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKAGLIRLIGNP 198
Cdd:COG0617 81 VATARTERYYGDGRRP------------FVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 199 ETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGHGFATYQLLREYSLFQPLfpt 278
Cdd:COG0617 149 EERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 279 itrnftekgdsameriidqvlkntdnriqndmrvnpAFLFAAMFwYPLLETAQKiaqESGLAYYDAFALATNDVLDEACR 358
Cdd:COG0617 226 ------------------------------------ALRLAALL-HDLGKPATR---EDGLPTFHGHEEAGAELAEALLK 265
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2314193603 359 SLAIPKRITTLVRDIWQLQLRMSRRQGKRAW---KLMEHpKFRAAYDLMALRAEAENNRELQ-----LLVQWWGEFQ 427
Cdd:COG0617 266 RLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQerlaeLLEAAWRRFQ 341
|
|
| PRK13299 |
PRK13299 |
tRNA CCA-pyrophosphorylase; Provisional |
42-273 |
3.47e-51 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237339 [Multi-domain] Cd Length: 394 Bit Score: 178.11 E-value: 3.47e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 42 KDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVA 121
Cdd:PRK13299 3 PSEFQKALPILEKIKEAGFEAYFVGGSVRDYLLGRPIHDVDIATSAYPEEVKAIFPRTVDVGIEHGTVLVLENGEEYEVT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 122 TFRGhhEGT------PSDRTTSQqgqngmllrdnifgSIEEDAQRRDFTINSLYYSvADFTVRDFVGGVPDLKAGLIRLI 195
Cdd:PRK13299 83 TFRT--ESEyvdyrrPSEVTFVR--------------SLEEDLKRRDFTINAIAMD-ENGEIIDLFDGLEDLKNRLIRAV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2314193603 196 GNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGHGFATYQLLREYSLFQ 273
Cdd:PRK13299 146 GNAEERFQEDALRMMRAVRFASQLGFDLETETFEAMKTQAPLLEKISVERIFVEFEKLLLGPFWRKGLKLLIETGLYN 223
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
62-193 |
1.13e-48 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 162.83 E-value: 1.13e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 62 AYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLV----GRRFRLAHVMFGPEIIEVATFRGHHEgtPSDRTTS 137
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLFRRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEFD--ESDFRNP 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2314193603 138 QQGQNGmllrdnifGSIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKAGLIR 193
Cdd:pfam01743 79 RSEEYT--------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| PolyA_pol_arg_C |
pfam12626 |
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is ... |
337-444 |
5.49e-44 |
|
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is arginine-rich and is necessary for full functioning of the enzyme.
Pssm-ID: 463647 [Multi-domain] Cd Length: 116 Bit Score: 150.04 E-value: 5.49e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 337 SGLAYYDAFALATNDVLDEACRSLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDLMALRAEAENnrEL 416
Cdd:pfam12626 1 QGLPPYDALQLAADEVLDEQCQRVAIPRRFTAPMREIWLLQPRLEKRQGKRPFRLLEHPRFRAAYDFLLLRAESGE--VL 78
|
90 100
....*....|....*....|....*...
gi 2314193603 417 QLLVQWWGEFQVSAPPAQKDMLGDLDED 444
Cdd:pfam12626 79 QELAEWWTRFQEADEAEREAMIAELGAD 106
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
45-189 |
2.16e-41 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 144.27 E-value: 2.16e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 45 SENALKVLYRLNKA-GYEAYLVGGGVRDLLLGKKPKDFDVTTSA-TPEQVRKLFR--NCRLVGR--RFRLAHVMFGPEII 118
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2314193603 119 EVATFRGHHEGTPSDRTTSqqgqngmllrdnIFGSIEEDAQRRDFTINSLYYSVADFTVRDFVGGVPDLKA 189
Cdd:cd05398 81 DVATLRTETYTDPGRRPPV------------VGFTIEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| PolyA_pol_RNAbd |
pfam12627 |
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA ... |
220-277 |
7.03e-19 |
|
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA and SrmB binding motifs on polymerase A.
Pssm-ID: 463648 [Multi-domain] Cd Length: 64 Bit Score: 80.22 E-value: 7.03e-19
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2314193603 220 DMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGHGFATYQLLREYSLFQPLFP 277
Cdd:pfam12627 1 GFTIEPETREAIRKLAPLLKKISPERIFEELLKLLLSGHPERGLELLRETGLLEYLFP 58
|
|
| cca |
PRK10885 |
multifunctional CCA addition/repair protein; |
63-229 |
2.45e-17 |
|
multifunctional CCA addition/repair protein;
Pssm-ID: 182810 [Multi-domain] Cd Length: 409 Bit Score: 83.75 E-value: 2.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 63 YLVGGGVRDLLLGKKPKDFD-VTTSATPEQVrkLFRNCRLVGRRFRlahVMFGPEIievatfrghHEGTPSDRT--TSQQ 139
Cdd:PRK10885 4 YLVGGAVRDALLGLPVKDRDwVVVGATPEEM--LAQGYQQVGKDFP---VFLHPKT---------HEEYALARTerKSGR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 140 GQNGMllrdnIFG-----SIEEDAQRRDFTINSLYYSvADFTVRDFVGGVPDLKAGLIRLIGNPetrYREDPVRMLRAVR 214
Cdd:PRK10885 70 GYTGF-----TCYaapdvTLEEDLIRRDLTINAMAQD-DDGELIDPYGGQRDLEARLLRHVSPA---FAEDPLRVLRVAR 140
|
170
....*....|....*...
gi 2314193603 215 FAAK---LDMRISPETAE 229
Cdd:PRK10885 141 FAARfahLGFRIAPETLA 158
|
|
| PRK13298 |
PRK13298 |
tRNA CCA-pyrophosphorylase; Provisional |
61-279 |
4.36e-16 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237338 [Multi-domain] Cd Length: 417 Bit Score: 79.77 E-value: 4.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 61 EAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVrkLFRNCRLVGRRFRlahVMFGPEiievatfrgHHEGTPSDRT--TS 137
Cdd:PRK13298 2 KIYLVGGAVRDSLLNLPVKDKDwVVVGGTPKIL--LSINFQQVGKDFP---VFLHPE---------THEEYALARTerKS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 138 QQGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSvADFTVRDFVGGVPDLKAGLIRLIGNPetrYREDPVRMLRAVRFAA 217
Cdd:PRK13298 68 GVGYTGFITDTSSDVTLEEDLIRRDLTINAIAQD-ENGNYIDPFQGKKDIQLRLLRHVSES---FIEDPLRVLRVARFAA 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2314193603 218 K---LDMRISPETAEPIPRLAT---LINdVPPARLFEEALKLLQAGHGFATYQLLREYSLFQPLFPTI 279
Cdd:PRK13298 144 LlvhLGFKIAKETMILMCIMVKkheLLY-LTPERIWNETEKALKTDNPHVYFQVLYECNALKFLFPEI 210
|
|
| PRK13297 |
PRK13297 |
tRNA CCA-pyrophosphorylase; Provisional |
58-256 |
1.15e-15 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 139469 [Multi-domain] Cd Length: 364 Bit Score: 78.11 E-value: 1.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 58 AGYEAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVRKlfRNCRLVGRRFRlahVMFGPEIIE-VATFRGHHEgtpsdrt 135
Cdd:PRK13297 10 AGLQVYIVGGAVRDALLGLPAGDRDwVVVGATPEDMAR--RGFIPVGGDFP---VFLHPRTKEeYALARTERK------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 136 tSQQGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVrDFVGGVPDLKAGLIRLIGNPetrYREDPVRMLRAVRF 215
Cdd:PRK13297 78 -SGRGYKGFTFYTGADVTLEQDLQRRDLTVNAIARTPQGELV-DPLDGVADVRARVLRHVGEA---FAEDPVRILRLGRF 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2314193603 216 AAKL-DMRISPETAEPIPRL--ATLINDVPPARLFEEALKLLQA 256
Cdd:PRK13297 153 AARFgDFSIAPETMQLCRRMveAGEADALVPERVWKEVSRGLMA 196
|
|
| PRK13296 |
PRK13296 |
CCA tRNA nucleotidyltransferase; |
61-308 |
1.99e-14 |
|
CCA tRNA nucleotidyltransferase;
Pssm-ID: 106256 [Multi-domain] Cd Length: 360 Bit Score: 74.25 E-value: 1.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 61 EAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVRKlfrncrlVGRRFRLAH--VMFGPEII-EVATFRghhegtpSDRTT 136
Cdd:PRK13296 2 KFYLVGGAVRDMLLGITPKDKDwVVVGATEDEMLA-------NGFIKIAANfpVFIHPQTKqEYALAR-------SEKKT 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 137 SQqGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDFvGGVPDLKAgliRLIGNPETRYREDPVRMLRAVRFA 216
Cdd:PRK13296 68 AS-GYHGFEVNFSKYITLEDDLKRRDLTINSIAIDQNNKVIDPF-NGQADLQN---RILRHTSIAFIEDPLRVVRLARFK 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2314193603 217 AKL---DMRISPETAEPIPRLATL--INDVPPARLFEEALKLLQAGHGFatYQLLREYSLFQPLFPTIT----------- 280
Cdd:PRK13296 143 AQLsnfNFSIAQEMLALIKELVKTgeLNHLTRERLHIEFVKALNNPKIF--FTTLKELEALKIIFPNIScilplipnksf 220
|
250 260
....*....|....*....|....*....
gi 2314193603 281 -RNFTEKGDSAMERIIDQVLKNTDNRIQN 308
Cdd:PRK13296 221 fENPIYKGSNINEKITLCLLKIPQQQLDD 249
|
|
| PHA01806 |
PHA01806 |
hypothetical protein |
29-95 |
6.41e-05 |
|
hypothetical protein
Pssm-ID: 222838 Cd Length: 200 Bit Score: 43.72 E-value: 6.41e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2314193603 29 MSVIPREQHaISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTT-SATPEQVRKL 95
Cdd:PHA01806 6 SDLLEGTKE-IPEGLIAKALLLRLYSDARHSEGVALAGGAARDLMHGAEPKDIDIALyGMDDRQAELL 72
|
|
| |
