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Conserved domains on  [gi|2303874579|ref|WP_260408688|]
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IS3 family transposase [Planomonospora venezuelensis]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 super family cl41295
IS3 family transposase;
2-368 1.70e-132

IS3 family transposase;


The actual alignment was detected with superfamily member NF033516:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 383.84  E-value: 1.70e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579   2 VELVR-AGRSPEELAREFEPSAQSIRTWARQAD----LDDGRRSDGLTSAEKDELARLRREVKILREEKEIPAQGRGFLR 76
Cdd:NF033516    7 VREVLeGGKSVAEVARELGISPSTLYRWRKKYRgggeAADAGRLKELLTPEEEENRRLKRELAELRLENEILKKARKLLR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  77 AgdgsaEMRFRLIDAENDHHDVSLLARVLGVSRQGYYAWRRRQqrgPSARARRDAELTEKIRAHHAASDGIYGAPRIHAD 156
Cdd:NF033516   87 P-----AVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRP---PSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 157 LREvDGIRIGRKRVARLMRTAGLSGVTRRK-GCRTTLADRRAAAASDLVKRQFTAEEPNRLWTADITYVPTGQGFLYLAV 235
Cdd:NF033516  159 LRR-EGIRVNHKRVYRLMRELGLLARRRRKrRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 236 VLDVFSRRIVGWAMAEHMRTELVTDALAMAIHQRRPNAGVIHHSDKGGQYTSVAFGQRCARAGVRPSTGRTGTCFDNAIT 315
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2303874579 316 ESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSPAEYE 368
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
2-368 1.70e-132

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 383.84  E-value: 1.70e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579   2 VELVR-AGRSPEELAREFEPSAQSIRTWARQAD----LDDGRRSDGLTSAEKDELARLRREVKILREEKEIPAQGRGFLR 76
Cdd:NF033516    7 VREVLeGGKSVAEVARELGISPSTLYRWRKKYRgggeAADAGRLKELLTPEEEENRRLKRELAELRLENEILKKARKLLR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  77 AgdgsaEMRFRLIDAENDHHDVSLLARVLGVSRQGYYAWRRRQqrgPSARARRDAELTEKIRAHHAASDGIYGAPRIHAD 156
Cdd:NF033516   87 P-----AVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRP---PSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 157 LREvDGIRIGRKRVARLMRTAGLSGVTRRK-GCRTTLADRRAAAASDLVKRQFTAEEPNRLWTADITYVPTGQGFLYLAV 235
Cdd:NF033516  159 LRR-EGIRVNHKRVYRLMRELGLLARRRRKrRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 236 VLDVFSRRIVGWAMAEHMRTELVTDALAMAIHQRRPNAGVIHHSDKGGQYTSVAFGQRCARAGVRPSTGRTGTCFDNAIT 315
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2303874579 316 ESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSPAEYE 368
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
47-372 4.40e-96

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 288.98  E-value: 4.40e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  47 EKDELARLRREVKILREEKEIPAQGRGFLRAGDGSAEMRFRLidaendhhdvsllaRVLGVSRQGYYAWRRRQQRGPSAR 126
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRL--------------LRLLRRRRARSRRRRRLRRPRSYR 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 127 ARRDAELTEKIRAHHAASdGIYGAPRIHADLREvDGIRIGRKRVARLMRTAGLSGVTRRKGCRTTLADRRAAAASDLVkr 206
Cdd:COG2801    67 ADEDAELLERIKEIFAES-PRYGYRRITAELRR-EGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL-- 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 207 qFTAEEPNRLWTADITYVPTGQGFLYLAVVLDVFSRRIVGWAMAEHMRTELVTDALAMAIHQRRPNAGVIHHSDKGGQYT 286
Cdd:COG2801   143 -FTATAPNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYT 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 287 SVAFGQRCARAGVRPSTGRTGTCFDNAITESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSPAE 366
Cdd:COG2801   222 SKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAE 300


                  ....*.
gi 2303874579 367 YERRQA 372
Cdd:COG2801   301 YEKQLA 306
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 105-383 3.40e-87

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 265.19  E-value: 3.40e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 105 LGVSRQGYYAWRRRQQR--GPSARARRDAELTEKIRAHHAASDGIYGAPRIHADL-REvdGIRIGRKRVARLMRTAGLSG 181
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHHpdKRRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLnRE--GIRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 182 VTRRKGCRTTLADRRAAAASdLVKRQFTAEEPNRLWTADITYVPTGQGFLYLAVVLDVFSRRIVGWAMAEHMRTELVTDA 261
Cdd:PHA02517   79 VLRGKKVRTTISRKAVAAPD-RVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 262 LAMAIHQRRPNAGVIHHSDKGGQYTSVAFGQRCARAGVRPSTGRTGTCFDNAITESFFASLECELLDRRTFRTRSEAERA 341
Cdd:PHA02517  158 LEQALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELA 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2303874579 342 VFAYIeGFYNPRRRHSANGQLSPAEYERRqALKNVHQDGYAA 383
Cdd:PHA02517  238 TLEWV-AWYNNRRLHERLGYTPPAEAEKA-YYASIGNNDVAA 277
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 213-309 4.29e-29

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 108.56  E-value: 4.29e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 213 PNRLWTADITYV--PTGQGFLYLAVVLDVFSRRIVGWAMAEHMRTELVTDALAMAIHQRRPnAGVIHHSDKGGQYTSVAF 290
Cdd:pfam00665   1 PNQLWQGDFTYIriPGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGG-VPLIIHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 2303874579 291 GQRCARAGVRPSTGRTGTC 309
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 85-366 1.21e-19

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 88.03  E-value: 1.21e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  85 RFRLID-AENDHHDVSLLARVLGVSRQGYYAWRRR-----------QQRGPSARARRDAELTEKI----RAHHAasdgiY 148
Cdd:NF033577    2 RLELVRlVLEDGWSVREAARRFGISRKTVYKWLKRyraggeeglidRSRRPHRSPRRTSPETEARilalRRELR-----L 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 149 GAPRIHADLREvDGIRIGRKRVARLMRTAGLSGVTRRKGcrttladrraaaASDLVKRqFTAEEPNRLWTADITYVPT-- 226
Cdd:NF033577   77 GPRRIAYELER-QGPGVSRSTVHRILRRHGLSRLRALDR------------KTGKVKR-YERAHPGELWHIDIKKLGRip 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 227 GQGFLYLAVVLDVFSRRIVGWAMAEHmRTELVTDALAMAIHQRrpnaGVIHH---SDKGGQYTSVA--FGQRCARAGVRP 301
Cdd:NF033577  143 DVGRLYLHTAIDDHSRFAYAELYPDE-TAETAADFLRRAFAEH----GIPIRrvlTDNGSEFRSRAhgFELALAELGIEH 217

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2303874579 302 STGRTGTCFDNAITESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSPAE 366
Cdd:NF033577  218 RRTRPYHPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPAE 281
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
2-368 1.70e-132

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 383.84  E-value: 1.70e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579   2 VELVR-AGRSPEELAREFEPSAQSIRTWARQAD----LDDGRRSDGLTSAEKDELARLRREVKILREEKEIPAQGRGFLR 76
Cdd:NF033516    7 VREVLeGGKSVAEVARELGISPSTLYRWRKKYRgggeAADAGRLKELLTPEEEENRRLKRELAELRLENEILKKARKLLR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  77 AgdgsaEMRFRLIDAENDHHDVSLLARVLGVSRQGYYAWRRRQqrgPSARARRDAELTEKIRAHHAASDGIYGAPRIHAD 156
Cdd:NF033516   87 P-----AVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRP---PSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 157 LREvDGIRIGRKRVARLMRTAGLSGVTRRK-GCRTTLADRRAAAASDLVKRQFTAEEPNRLWTADITYVPTGQGFLYLAV 235
Cdd:NF033516  159 LRR-EGIRVNHKRVYRLMRELGLLARRRRKrRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 236 VLDVFSRRIVGWAMAEHMRTELVTDALAMAIHQRRPNAGVIHHSDKGGQYTSVAFGQRCARAGVRPSTGRTGTCFDNAIT 315
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2303874579 316 ESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSPAEYE 368
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
47-372 4.40e-96

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 288.98  E-value: 4.40e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  47 EKDELARLRREVKILREEKEIPAQGRGFLRAGDGSAEMRFRLidaendhhdvsllaRVLGVSRQGYYAWRRRQQRGPSAR 126
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRL--------------LRLLRRRRARSRRRRRLRRPRSYR 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 127 ARRDAELTEKIRAHHAASdGIYGAPRIHADLREvDGIRIGRKRVARLMRTAGLSGVTRRKGCRTTLADRRAAAASDLVkr 206
Cdd:COG2801    67 ADEDAELLERIKEIFAES-PRYGYRRITAELRR-EGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL-- 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 207 qFTAEEPNRLWTADITYVPTGQGFLYLAVVLDVFSRRIVGWAMAEHMRTELVTDALAMAIHQRRPNAGVIHHSDKGGQYT 286
Cdd:COG2801   143 -FTATAPNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYT 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 287 SVAFGQRCARAGVRPSTGRTGTCFDNAITESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSPAE 366
Cdd:COG2801   222 SKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAE 300


                  ....*.
gi 2303874579 367 YERRQA 372
Cdd:COG2801   301 YEKQLA 306
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 105-383 3.40e-87

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 265.19  E-value: 3.40e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 105 LGVSRQGYYAWRRRQQR--GPSARARRDAELTEKIRAHHAASDGIYGAPRIHADL-REvdGIRIGRKRVARLMRTAGLSG 181
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHHpdKRRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLnRE--GIRVARCTVGRLMKELGLAG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 182 VTRRKGCRTTLADRRAAAASdLVKRQFTAEEPNRLWTADITYVPTGQGFLYLAVVLDVFSRRIVGWAMAEHMRTELVTDA 261
Cdd:PHA02517   79 VLRGKKVRTTISRKAVAAPD-RVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 262 LAMAIHQRRPNAGVIHHSDKGGQYTSVAFGQRCARAGVRPSTGRTGTCFDNAITESFFASLECELLDRRTFRTRSEAERA 341
Cdd:PHA02517  158 LEQALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELA 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2303874579 342 VFAYIeGFYNPRRRHSANGQLSPAEYERRqALKNVHQDGYAA 383
Cdd:PHA02517  238 TLEWV-AWYNNRRLHERLGYTPPAEAEKA-YYASIGNNDVAA 277
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 213-309 4.29e-29

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 108.56  E-value: 4.29e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 213 PNRLWTADITYV--PTGQGFLYLAVVLDVFSRRIVGWAMAEHMRTELVTDALAMAIHQRRPnAGVIHHSDKGGQYTSVAF 290
Cdd:pfam00665   1 PNQLWQGDFTYIriPGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGG-VPLIIHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 2303874579 291 GQRCARAGVRPSTGRTGTC 309
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 85-366 1.21e-19

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 88.03  E-value: 1.21e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  85 RFRLID-AENDHHDVSLLARVLGVSRQGYYAWRRR-----------QQRGPSARARRDAELTEKI----RAHHAasdgiY 148
Cdd:NF033577    2 RLELVRlVLEDGWSVREAARRFGISRKTVYKWLKRyraggeeglidRSRRPHRSPRRTSPETEARilalRRELR-----L 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 149 GAPRIHADLREvDGIRIGRKRVARLMRTAGLSGVTRRKGcrttladrraaaASDLVKRqFTAEEPNRLWTADITYVPT-- 226
Cdd:NF033577   77 GPRRIAYELER-QGPGVSRSTVHRILRRHGLSRLRALDR------------KTGKVKR-YERAHPGELWHIDIKKLGRip 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 227 GQGFLYLAVVLDVFSRRIVGWAMAEHmRTELVTDALAMAIHQRrpnaGVIHH---SDKGGQYTSVA--FGQRCARAGVRP 301
Cdd:NF033577  143 DVGRLYLHTAIDDHSRFAYAELYPDE-TAETAADFLRRAFAEH----GIPIRrvlTDNGSEFRSRAhgFELALAELGIEH 217

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2303874579 302 STGRTGTCFDNAITESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSPAE 366
Cdd:NF033577  218 RRTRPYHPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPAE 281
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 128-186 3.71e-15

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 69.13  E-value: 3.71e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2303874579 128 RRDAELTEKIRAHHAASDGIYGAPRIHADLREVDGIRIGRKRVARLMRTAGLSGVTRRK 186
Cdd:pfam13276   1 ELEDELLEAIREIFEESRGTYGYRRITAELRREGGIRVNRKRVARLMRELGLRARRRRK 59
rve_3 pfam13683
Integrase core domain;
298-364 9.41e-10

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 54.14  E-value: 9.41e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2303874579 298 GVRPSTGRTGTCFDNAITESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSANGQLSP 364
Cdd:pfam13683   2 GIEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWRE-DYNTERPHSSLGYRTP 67
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
 98-372 5.73e-08

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 53.95  E-value: 5.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579  98 VSLLARVLGVSRQGYYAWRRRQQRGPSARARRDAELTEKI-RAHHAASD-GIYGAPRIHADLR---EVDGI-RIGRKRVA 171
Cdd:PRK09409   14 VSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDVLlRIHHVIGElPTYGYRRVWALLRrqaELDGMpAINAKRVY 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 172 RLMRTAGLsgVTRRKGCRTTLADRRAAaasdlvkrQFTAEEPNRLWTAD-ITYVPTGQGFLYLAVVLDVFSRRIVGWAMA 250
Cdd:PRK09409   94 RIMRQNAL--LLERKPAVPPSKRAHTG--------RVAVKESNQRWCSDgFEFCCDNGERLRVTFALDCCDREALHWAVT 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 251 EH-MRTELVTDALAMAIHQR----RPNAGVIHHSDKGGQYTSVAFGQRCARAGVRPSTGRTGTCFDNAITESFFASLEce 325
Cdd:PRK09409  164 TGgFNSETVQDVMLGAVERRfgndLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIK-- 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 2303874579 326 lLDRRTFRTRSEAERAVFAYIEGF--YNPRRRHSANGQLSPAEYERRQA 372
Cdd:PRK09409  242 -RDYISIMPKPDGLTAAKNLAEAFehYNEWHPHSALGYRSPREYLRQRA 289
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-75 8.15e-08

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 49.54  E-value: 8.15e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2303874579   1 MVELVRA-GRSPEELAREFEPSAQSIRTWARQADLD--DGRRSDGLTSAEKDELARLRREVKILREEKEIPAQGRGFL 75
Cdd:COG2963    16 AVRLVLEgGASVAEVARELGISPSTLYRWVRQYREGglGGFPGDGRTTPEQAEIRRLRKELRRLEMENDILKKAAALL 93
rve_2 pfam13333
Integrase core domain;
316-373 3.03e-07

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 46.87  E-value: 3.03e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2303874579 316 ESFFASLECELLDRRTFRTRSEAERAVFAYIEgFYNPRRRHSangqLSPAEYeRRQAL 373
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIE-WYNNKRLKG----LSPVQY-RNQSL 52
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
 122-372 1.53e-05

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 45.88  E-value: 1.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 122 GPSARARRDAELTekIRAHHAASD-GIYGAPRIHADLR---EVDGI-RIGRKRVARLMRTAGLsgVTRRKGCRTTLADRR 196
Cdd:PRK14702    2 GRRSRHTDDTDVL--LRIHHVIGElPTYGYRRVWALLRrqaELDGMpAINAKRVYRLMRQNAL--LLERKPAVPPSKRAH 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 197 AAaasdlvkrQFTAEEPNRLWTAD-ITYVPTGQGFLYLAVVLDVFSRRIVGWAMAEH-MRTELVTDALAMAIHQR----R 270
Cdd:PRK14702   78 TG--------RVAVKESNQRWCSDgFEFCCDNGERLRVTFALDCCDREALHWAVTTGgFNSETVQDVMLGAVERRfgndL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2303874579 271 PNAGVIHHSDKGGQYTSVAFGQRCARAGVRPSTGRTGTCFDNAITESFFASLEcelLDRRTFRTRSEAERAVFAYIEGF- 349
Cdd:PRK14702  150 PSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIK---RDYISIMPKPDGLTAAKNLAEAFe 226

                         250       260
                  ....*....|....*....|....
gi 2303874579 350 -YNPRRRHSANGQLSPAEYERRQA 372
Cdd:PRK14702  227 hYNEWHPHSALGYRSPREYLRQRA 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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