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Conserved domains on  [gi|2278214013|ref|WP_255371549|]
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LysR family transcriptional regulator [Cupriavidus sp. YR651]

Protein Classification

LysR family transcriptional regulator( domain architecture ID 10444001)

LysR family HTH-containing transcriptional regulator similar to Streptomyces cacaoi BlaA, which functions as a positive regulator for the expression of the gene (blaB) for beta-lactamase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
1-55 5.14e-05

Bacterial regulatory helix-turn-helix protein, lysR family;


:

Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 38.91  E-value: 5.14e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2278214013   1 MRTFARVVIDGGFAPAARKLDLTTGQISRAISYLESRPGRRLLQRTTRRVALTEA 55
Cdd:pfam00126   4 LRLFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFERTTRGVRLTEA 58
 
Name Accession Description Interval E-value
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
1-55 5.14e-05

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 38.91  E-value: 5.14e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2278214013   1 MRTFARVVIDGGFAPAARKLDLTTGQISRAISYLESRPGRRLLQRTTRRVALTEA 55
Cdd:pfam00126   4 LRLFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFERTTRGVRLTEA 58
PRK14997 PRK14997
LysR family transcriptional regulator; Provisional
 4-75 2.49e-04

LysR family transcriptional regulator; Provisional


Pssm-ID: 184959 [Multi-domain]  Cd Length: 301  Bit Score: 39.59  E-value: 2.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2278214013   4 FARVVIDGGFAPAARKLDLTTGQISRAISYLESRPGRRLLQRTTRRVALTEA------------VGLEAA---------- 61
Cdd:PRK14997   10 FVHVVEEGGFAAAGRALDEPKSKLSRRIAQLEERLGVRLIQRTTRQFNVTEVgqtfyehckamlVEAQAAqdaiaalqve 89

                          90
                  ....*....|....*
gi 2278214013  62 -RGPWRLSSPNSVVH 75
Cdd:PRK14997   90 pRGIVKLTCPVTLLH 104
 
Name Accession Description Interval E-value
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
1-55 5.14e-05

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 38.91  E-value: 5.14e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2278214013   1 MRTFARVVIDGGFAPAARKLDLTTGQISRAISYLESRPGRRLLQRTTRRVALTEA 55
Cdd:pfam00126   4 LRLFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFERTTRGVRLTEA 58
PRK14997 PRK14997
LysR family transcriptional regulator; Provisional
 4-75 2.49e-04

LysR family transcriptional regulator; Provisional


Pssm-ID: 184959 [Multi-domain]  Cd Length: 301  Bit Score: 39.59  E-value: 2.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2278214013   4 FARVVIDGGFAPAARKLDLTTGQISRAISYLESRPGRRLLQRTTRRVALTEA------------VGLEAA---------- 61
Cdd:PRK14997   10 FVHVVEEGGFAAAGRALDEPKSKLSRRIAQLEERLGVRLIQRTTRQFNVTEVgqtfyehckamlVEAQAAqdaiaalqve 89

                          90
                  ....*....|....*
gi 2278214013  62 -RGPWRLSSPNSVVH 75
Cdd:PRK14997   90 pRGIVKLTCPVTLLH 104
PRK13348 PRK13348
HTH-type transcriptional regulator ArgP;
2-39 9.99e-04

HTH-type transcriptional regulator ArgP;


Pssm-ID: 237357 [Multi-domain]  Cd Length: 294  Bit Score: 37.64  E-value: 9.99e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2278214013   2 RTFARVVIDGGFAPAARKLDLTTGQISRAISYLESRPG 39
Cdd:PRK13348    8 EALAAVVETGSFERAARRLHVTPSAVSQRIKALEESLG 45
PRK10632 PRK10632
HTH-type transcriptional activator AaeR;
1-55 2.56e-03

HTH-type transcriptional activator AaeR;


Pssm-ID: 182601 [Multi-domain]  Cd Length: 309  Bit Score: 36.66  E-value: 2.56e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2278214013   1 MRTFARVVIDGGFAPAARKLDLTTGQISRAISYLESRPGRRLLQRTTRRVALTEA 55
Cdd:PRK10632    7 MSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEA 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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