|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
3-416 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 637.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 3 EHFRVQGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEGD-VATITTPAELN 81
Cdd:PRK09369 2 DKLVIEGGKPLSGEVTISGAKNAALPILAASLLAEEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDGNgTVTIDASNINN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 82 HRADSEAMGKLRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQG-LHGAQVWLD 160
Cdd:PRK09369 82 TEAPYELVKKMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDLHLKGLEALGAEIEIEHGYVEAKADGrLKGAHIVLD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 161 FPSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWA 240
Cdd:PRK09369 162 FPSVGATENILMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKISGAGTDTITIEGVERLHGAEHTVIPDRIEAGTFL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 241 FAAAMTRGDITVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEGRPESVDFVTLPYPGFATDLQPFAIALSAVSAGT 320
Cdd:PRK09369 242 VAAAITGGDVTIRGARPEHLEAVLAKLREAGAEIEEGEDGIRVDMPGRLKAVDIKTAPYPGFPTDMQAQFMALLTQAEGT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 321 SMITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYP 400
Cdd:PRK09369 322 SVITETIFENRFMHVPELIRMGADIEVDGHTAVVRGVEKLSGAPVMATDLRASASLVLAGLVAEGTTIVDRIYHLDRGYE 401
|
410
....*....|....*.
gi 2267612541 401 GFVENLRKLGATVERV 416
Cdd:PRK09369 402 RIEEKLRALGADIERV 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
3-416 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 612.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 3 EHFRVQGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVT-IEGDVATITTPAELN 81
Cdd:COG0766 2 DKLIIEGGKPLSGEVRISGAKNAALPILAAALLTDGPVTLRNVPDLSDVRTMLELLESLGVKVErDDGGTLTIDASNINS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 82 HRADSEAMGKLRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQGLHGAQVWLDF 161
Cdd:COG0766 82 TEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHGYIEARAGRLKGARIYLDF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 162 PSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAF 241
Cdd:COG0766 162 PSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGTFLV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 242 AAAMTRGDITVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEGRPESVDFVTLPYPGFATDLQPFAIALSAVSAGTS 321
Cdd:COG0766 242 AAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAEGTS 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 322 MITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYPG 401
Cdd:COG0766 322 VITETVFENRFMHVDELNRMGADIKLDGHTAIVRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETVIDNIYHIDRGYEN 401
|
410
....*....|....*
gi 2267612541 402 FVENLRKLGATVERV 416
Cdd:COG0766 402 LEEKLRALGADIERV 416
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
3-415 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 544.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 3 EHFRVQGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATITTPAELNH 82
Cdd:TIGR01072 2 DKLVVEGGKPLSGEVTISGAKNAALPIIAATLLTDEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNINST 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 83 RADSEAMGKLRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQG-LHGAQVWLDF 161
Cdd:TIGR01072 82 EAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIVIEDGYVYASAKGrLVGAHIVLDK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 162 PSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAF 241
Cdd:TIGR01072 162 VSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTFLV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 242 AAAMTRGDITVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEG-RPESVDFVTLPYPGFATDLQPFAIALSAVSAGT 320
Cdd:TIGR01072 242 AAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDMRQkRLKAVDIETLPYPGFPTDLQAQFMALLSQAEGT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 321 SMITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYP 400
Cdd:TIGR01072 322 SVITETVFENRFMHVDELIRMGANIKLEGNTAVIHGVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRGYE 401
|
410
....*....|....*
gi 2267612541 401 GFVENLRKLGATVER 415
Cdd:TIGR01072 402 DLEEKLRALGAKIER 416
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
13-409 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 539.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 13 LVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEG-DVATITTPAELNHRADSEAMGK 91
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLTDEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGeNTLVIDASNINSTEAPYELVRK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 92 LRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAE-AQGLHGAQVWLDFPSVGATENI 170
Cdd:cd01555 81 MRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKaAGRLKGARIYLDFPSVGATENI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 171 LMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAFAAAMTRGDI 250
Cdd:cd01555 161 MMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGDI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 251 TVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEG-RPESVDFVTLPYPGFATDLQPFAIALSAVSAGTSMITENLFE 329
Cdd:cd01555 241 TVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVDGDGgRLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIFE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 330 ARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYPGFVENLRKL 409
Cdd:cd01555 321 NRFMHVDELNRMGADIKVEGNTAIIRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRAL 400
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
8-406 |
2.79e-110 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 330.41 E-value: 2.79e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 8 QGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVT-IEGDVATITTPAELNH-RAD 85
Cdd:pfam00275 1 TGGSRLSGEVKIPGSKSNSHRALILAALAAGESTITNLLDSDDTLTMLEALRALGAEIIkLDDEKSVVIVEGLGGSfEAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 86 SEAMGKLRASVCVLGPLVGRCKRAV--VALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVA----EAQGLHGAQVWL 159
Cdd:pfam00275 81 EDLVLDMGNSGTALRPLTGRLALQSgeVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAplkvRGLRLGGIHIDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 160 DFPSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTST-LTVHGVPELHPTEHRVIGDRIVGAT 238
Cdd:pfam00275 161 DVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTELsITVKGGEKLPGQEYRVEGDRSSAAY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 239 WAFAAAMTRGDITVRGVDPKHI---NLVLEKLRTAGATVTTGENEFRVVQEG--RPESVDFVTLPYPGFATDLQPFAIAL 313
Cdd:pfam00275 241 FLVAAAITGGTVTVENVGINSLqgdEALLEILEKMGAEITQEEDADIVVGPPglRGKAVDIRTAPDPAPTTAVLAAFAEG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 314 SAVSAGTSMITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVE-RLSSAPVWAS-DIRAGAGLVLAGLCADGATEVYE 391
Cdd:pfam00275 321 TTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkELKGAEVDSYgDHRIAMALALAGLVAEGETIIDD 400
|
410
....*....|....*
gi 2267612541 392 IFHIERGYPGFVENL 406
Cdd:pfam00275 401 IECTDRSFPDFEEKL 415
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
3-416 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 637.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 3 EHFRVQGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEGD-VATITTPAELN 81
Cdd:PRK09369 2 DKLVIEGGKPLSGEVTISGAKNAALPILAASLLAEEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDGNgTVTIDASNINN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 82 HRADSEAMGKLRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQG-LHGAQVWLD 160
Cdd:PRK09369 82 TEAPYELVKKMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDLHLKGLEALGAEIEIEHGYVEAKADGrLKGAHIVLD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 161 FPSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWA 240
Cdd:PRK09369 162 FPSVGATENILMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKISGAGTDTITIEGVERLHGAEHTVIPDRIEAGTFL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 241 FAAAMTRGDITVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEGRPESVDFVTLPYPGFATDLQPFAIALSAVSAGT 320
Cdd:PRK09369 242 VAAAITGGDVTIRGARPEHLEAVLAKLREAGAEIEEGEDGIRVDMPGRLKAVDIKTAPYPGFPTDMQAQFMALLTQAEGT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 321 SMITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYP 400
Cdd:PRK09369 322 SVITETIFENRFMHVPELIRMGADIEVDGHTAVVRGVEKLSGAPVMATDLRASASLVLAGLVAEGTTIVDRIYHLDRGYE 401
|
410
....*....|....*.
gi 2267612541 401 GFVENLRKLGATVERV 416
Cdd:PRK09369 402 RIEEKLRALGADIERV 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
3-416 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 612.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 3 EHFRVQGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVT-IEGDVATITTPAELN 81
Cdd:COG0766 2 DKLIIEGGKPLSGEVRISGAKNAALPILAAALLTDGPVTLRNVPDLSDVRTMLELLESLGVKVErDDGGTLTIDASNINS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 82 HRADSEAMGKLRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQGLHGAQVWLDF 161
Cdd:COG0766 82 TEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHGYIEARAGRLKGARIYLDF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 162 PSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAF 241
Cdd:COG0766 162 PSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGTFLV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 242 AAAMTRGDITVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEGRPESVDFVTLPYPGFATDLQPFAIALSAVSAGTS 321
Cdd:COG0766 242 AAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAEGTS 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 322 MITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYPG 401
Cdd:COG0766 322 VITETVFENRFMHVDELNRMGADIKLDGHTAIVRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETVIDNIYHIDRGYEN 401
|
410
....*....|....*
gi 2267612541 402 FVENLRKLGATVERV 416
Cdd:COG0766 402 LEEKLRALGADIERV 416
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
3-415 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 544.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 3 EHFRVQGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATITTPAELNH 82
Cdd:TIGR01072 2 DKLVVEGGKPLSGEVTISGAKNAALPIIAATLLTDEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNINST 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 83 RADSEAMGKLRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQG-LHGAQVWLDF 161
Cdd:TIGR01072 82 EAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIVIEDGYVYASAKGrLVGAHIVLDK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 162 PSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAF 241
Cdd:TIGR01072 162 VSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTFLV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 242 AAAMTRGDITVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEG-RPESVDFVTLPYPGFATDLQPFAIALSAVSAGT 320
Cdd:TIGR01072 242 AAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDMRQkRLKAVDIETLPYPGFPTDLQAQFMALLSQAEGT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 321 SMITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYP 400
Cdd:TIGR01072 322 SVITETVFENRFMHVDELIRMGANIKLEGNTAVIHGVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRGYE 401
|
410
....*....|....*
gi 2267612541 401 GFVENLRKLGATVER 415
Cdd:TIGR01072 402 DLEEKLRALGAKIER 416
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
13-409 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 539.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 13 LVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEG-DVATITTPAELNHRADSEAMGK 91
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLTDEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGeNTLVIDASNINSTEAPYELVRK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 92 LRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAE-AQGLHGAQVWLDFPSVGATENI 170
Cdd:cd01555 81 MRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKaAGRLKGARIYLDFPSVGATENI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 171 LMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAFAAAMTRGDI 250
Cdd:cd01555 161 MMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGDI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 251 TVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEG-RPESVDFVTLPYPGFATDLQPFAIALSAVSAGTSMITENLFE 329
Cdd:cd01555 241 TVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVDGDGgRLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIFE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 330 ARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYPGFVENLRKL 409
Cdd:cd01555 321 NRFMHVDELNRMGADIKVEGNTAIIRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRAL 400
|
|
| PRK12830 |
PRK12830 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed |
3-418 |
2.14e-147 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed
Pssm-ID: 183779 Cd Length: 417 Bit Score: 425.04 E-value: 2.14e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 3 EHFRVQGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATITTPAELNH 82
Cdd:PRK12830 2 EKIVINGGKPLSGEVTISGAKNSAVALIPAAILADGPVTLDGVPDISDVHSLVDILEELGGKVKRDGDTLEIDPTGIQSM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 83 RADSEAMGKLRASVCVLGPLVGRCKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQGLHGAQVWLDFP 162
Cdd:PRK12830 82 PLPNGKVKSLRASYYFMGALLGRFKKAVVGLPGGCDLGPRPIDQHIKGFEALGAEVTNEGGAIYLKADELKGAHIYLDVV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 163 SVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAFA 242
Cdd:PRK12830 162 SVGATINIMLAAVKAKGRTVIENAAKEPEIIDVATLLNNMGANIKGAGTDVIRIEGVDELHGCRHTVIPDRIEAGTYMIL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 243 AAMTRGDITVRGVDPKHINLVLEKLRTAGATVTTGENEFRVVQEGRPESVDFVTLPYPGFATDL-QPFAiALSAVSAGTS 321
Cdd:PRK12830 242 AAACGGGVTINNVIPEHLESFIAKLEEMGVRVEVNEDSIFVEKQGNLKAVDIKTLPYPGFATDLqQPLT-PLLLKANGRS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 322 MITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWASDIRAGAGLVLAGLCADGATEVYEIFHIERGYPG 401
Cdd:PRK12830 321 VVTDTIYEKRFKHVDELKRMGANIKVEGRSAIITGPSKLTGAKVKATDLRAGAALVIAGLMAEGVTEITNIEHIDRGYSN 400
|
410
....*....|....*..
gi 2267612541 402 FVENLRKLGATVERVSV 418
Cdd:PRK12830 401 IIEKLKALGADIWREED 417
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
8-406 |
2.79e-110 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 330.41 E-value: 2.79e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 8 QGGARLVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVT-IEGDVATITTPAELNH-RAD 85
Cdd:pfam00275 1 TGGSRLSGEVKIPGSKSNSHRALILAALAAGESTITNLLDSDDTLTMLEALRALGAEIIkLDDEKSVVIVEGLGGSfEAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 86 SEAMGKLRASVCVLGPLVGRCKRAV--VALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVA----EAQGLHGAQVWL 159
Cdd:pfam00275 81 EDLVLDMGNSGTALRPLTGRLALQSgeVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAplkvRGLRLGGIHIDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 160 DFPSVGATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTST-LTVHGVPELHPTEHRVIGDRIVGAT 238
Cdd:pfam00275 161 DVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTELsITVKGGEKLPGQEYRVEGDRSSAAY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 239 WAFAAAMTRGDITVRGVDPKHI---NLVLEKLRTAGATVTTGENEFRVVQEG--RPESVDFVTLPYPGFATDLQPFAIAL 313
Cdd:pfam00275 241 FLVAAAITGGTVTVENVGINSLqgdEALLEILEKMGAEITQEEDADIVVGPPglRGKAVDIRTAPDPAPTTAVLAAFAEG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 314 SAVSAGTSMITENLFEARFRFIEEMVRLGADARTDGHHAVVRGVE-RLSSAPVWAS-DIRAGAGLVLAGLCADGATEVYE 391
Cdd:pfam00275 321 TTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkELKGAEVDSYgDHRIAMALALAGLVAEGETIIDD 400
|
410
....*....|....*
gi 2267612541 392 IFHIERGYPGFVENL 406
Cdd:pfam00275 401 IECTDRSFPDFEEKL 415
|
|
| EPT-like |
cd01554 |
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine ... |
13-409 |
2.39e-68 |
|
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.
Pssm-ID: 238795 Cd Length: 408 Bit Score: 222.09 E-value: 2.39e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 13 LVGEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATITTPAELNHRADSEA--MG 90
Cdd:cd01554 1 LHGIIRVPGDKSISHRSLIFASLAEGETKVYNILRGEDVLSTMQVLRDLGVEIEDKDGVITIQGVGMAGLKAPQNAlnLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 91 K-LRASVCVLGPLVGRCKRavVALPGGDAIGSRPLDMHQSGLRKLGAHSEIEHGCVVAEAQ---GLHGAQVWLD-FPSVG 165
Cdd:cd01554 81 NsGTAIRLISGVLAGADFE--VELFGDDSLSKRPMDRVTLPLKKMGASISGQEERDLPPLLkggKNLGPIHYEDpIASAQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 166 ATENILMAAVLADGTTVIDNAAREPEIVDICVMLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAFAAAM 245
Cdd:cd01554 159 VKSALMFAALLAKGETVIIEAAKEPTINHTENMLQTFGGHISVQGTKKIVVQGPQKLTGQKYVVPGDISSAAFFLVAAAI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 246 TRGDITVRGVDPKHINL-VLEKLRTAGATVTTGEnEFRVVQEGRPESVDFVTLPYPgFATDLQPFAIALSAVSAGTSMIT 324
Cdd:cd01554 239 APGRLVLQNVGINETRTgIIDVLRAMGAKIEIGE-DTISVESSDLKATEICGALIP-RLIDELPIIALLALQAQGTTVIK 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 325 ENLF------EARFRFIEEMVRLGADARTDGHHAVVRGVERLSSAPVWA-SDIRAGAGLVLAGLCADGATEVYEIFHIER 397
Cdd:cd01554 317 DAEElkvketDRIFVVADELNSMGADIEPTADGMIIKGKEKLHGARVNTfGDHRIGMMTALAALVADGEVELDRAEAINT 396
|
410
....*....|..
gi 2267612541 398 GYPGFVENLRKL 409
Cdd:cd01554 397 SYPSFFDDLESL 408
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
37-409 |
2.54e-21 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 95.16 E-value: 2.54e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 37 EGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATITTPAElnhradseamGKLRASVCVL-----G----PLVGrck 107
Cdd:COG0128 36 EGESTIRNLLESDDTLATLEALRALGAEIEELDGGTLRVTGVG----------GGLKEPDAVLdcgnsGttmrLLTG--- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 108 rAVVALPG-----GDA-IGSRPLDMHQSGLRKLGAH-SEIEHGC--VVAEAQGLHGAQVWLD------FPSvgAtenILM 172
Cdd:COG0128 103 -LLALQPGevvltGDEsLRKRPMGRLLDPLRQLGARiESRGGGYlpLTIRGGPLKGGEYEIPgsassqFKS--A---LLL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 173 AAVLADGTTVIDNAAREPEI--VDICV-MLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDrIVGAT-WAFAAAMTRG 248
Cdd:COG0128 177 AGPLAEGGLEITVTGELESKpyRDHTErMLRAFGVEVEVEGYRRFTVPGGQRYRPGDYTVPGD-ISSAAfFLAAAAITGS 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 249 DITVRGVDPKHI---NLVLEKLRTAGATVTTGENEFRVVQEG-RPESVDFVTLPypgfatDLQPFAIALSAVSAGTSMIT 324
Cdd:COG0128 256 EVTVEGVGLNSTqgdTGILDILKEMGADIEIENDGITVRGSPlKGIDIDLSDIP------DEAPTLAVLAAFAEGTTRIR 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 325 eNLFEARF----RF---IEEMVRLGADARTDGHHAVVRGVERLSSAPVWAS-DIR---AGAglvLAGLCADGATEVYEIF 393
Cdd:COG0128 330 -GAAELRVkesdRIaamATELRKLGADVEETEDGLIIEGGPKLKGAEVDSYgDHRiamAFA---VAGLRAEGPVTIDDAE 405
|
410
....*....|....*.
gi 2267612541 394 HIERGYPGFVENLRKL 409
Cdd:COG0128 406 CVAKSFPDFFELLESL 421
|
|
| EPSP_synthase |
cd01556 |
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase ... |
37-409 |
9.07e-21 |
|
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.
Pssm-ID: 238797 Cd Length: 409 Bit Score: 93.39 E-value: 9.07e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 37 EGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATITTPAELNHRADSEA-MGK----LRAsvcvLGPLVGRCKRAVV 111
Cdd:cd01556 25 EGESRIENLLDSDDTLATLEALRALGAKIEEEGGTVEIVGGGGLGLPPEAVLdCGNsgttMRL----LTGLLALQGGDSV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 112 aLPGGDAIGSRPLDMHQSGLRKLGAH--SEIEHGCV-VAEAQGLHG----------AQVwldfpsVGAtenILMAAVLAD 178
Cdd:cd01556 101 -LTGDESLRKRPMGRLVDALRQLGAEieGREGGGYPpLIGGGGLKGgeveipgavsSQF------KSA---LLLAAPLAE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 179 GTTVIDNAAREPEI-VDICV-MLQQMGARIEGAGTSTLTVHGVPELHPTEHRVIGDrIVGAT-WAFAAAMTRGDITVRGV 255
Cdd:cd01556 171 GPTTIIIGELESKPyIDHTErMLRAFGAEVEVDGYRTITVKGGQKYKGPEYTVEGD-ASSAAfFLAAAAITGSEIVIKNV 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 256 DP----KHINLVLEKLrtaGATVTTGENEFRVVQEGRPES---VDfvtlpyPGFATDLQPFAIALSAVSAGTSMITeNLF 328
Cdd:cd01556 250 GLnsgdTGIIDVLKEM---GADIEIGNEDTVVVESGGKLKgidID------GNDIPDEAPTLAVLAAFAEGPTRIR-NAA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 329 EARF----RfIEEMV----RLGADAR--TDGhhAVVRGVErLSSAPVWAS---DIRAGAGLVLAGLCADGATEVYEIFHI 395
Cdd:cd01556 320 ELRVkesdR-IAAMAtelrKLGADVEetEDG--LIIEGGP-LKGAGVEVYtygDHRIAMSFAIAGLVAEGGVTIEDPECV 395
|
410
....*....|....
gi 2267612541 396 ERGYPGFVENLRKL 409
Cdd:cd01556 396 AKSFPNFFEDLESL 409
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
37-411 |
8.23e-19 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 87.72 E-value: 8.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 37 EGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATITTPAElnhrADSEAMGKLRASVCVLGPLVGrckraVVALPGG 116
Cdd:TIGR01356 23 EGETRVRNLLRSEDTLATLDALRALGAKIEDGGEVAVIEGVGG----KEPQAELDLGNSGTTARLLTG-----VLALADG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 117 -------DAIGSRPLDMHQSGLRKLGA--HSEIEHGCV-VAEAQGLHGAQVWLDfPSVGA--TENILMAAVLADGTTVID 184
Cdd:TIGR01356 94 evvltgdESLRKRPMGRLVDALRQLGAeiSSLEGGGSLpLTISGPLPGGIVYIS-GSASSqyKSALLLAAPALQAVGITI 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 185 NAAREPEIVDICVMLQQMGA---RIEGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAFAAAMTRGDITVRGVDP---- 257
Cdd:TIGR01356 173 VGEPLKSRPYIEITLDLLGSfgvEVERSDGRKIVVPGGQKYGPQGYDVPGDYSSAAFFLAAAAITGGRVTLENLGInptq 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 258 --KHINLVLEKLrtaGATVTTGENEFRVVQ--EGRPESVDFVTLPypgfatDLQPFAIALSAVSAGTSMITeNLFEARFR 333
Cdd:TIGR01356 253 gdKAIIIVLEEM---GADIEVEEDDLIVEGasGLKGIKIDMDDMI------DELPTLAVLAAFAEGVTRIT-GAEELRVK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 334 -------FIEEMVRLGADARTDGHHAVVRGVERLSSApVWAS--DIRAGAGLVLAGLCADGATEVYEIFHIERGYPGFVE 404
Cdd:TIGR01356 323 esdriaaIAEELRKLGVDVEEFEDGLYIRGKKELKGA-VVDTfgDHRIAMAFAVAGLVAEGEVLIDDPECVAKSFPSFFD 401
|
....*..
gi 2267612541 405 NLRKLGA 411
Cdd:TIGR01356 402 VLERLGA 408
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
124-414 |
2.23e-14 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 74.23 E-value: 2.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 124 LDMHQsGLRKLGAHSEIEHGCVVAEAQGLHGAQVWLDFPSVGATENILMAAV-LADGTTVI--DNAAREPEIVDICVMLQ 200
Cdd:TIGR01356 38 LATLD-ALRALGAKIEDGGEVAVIEGVGGKEPQAELDLGNSGTTARLLTGVLaLADGEVVLtgDESLRKRPMGRLVDALR 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 201 QMGARI---EGAGTSTLTVHGVPELHPTEHRVIGDRIVGATWAFAAAMTRGD-ITVRGVDPK---HINLVLEKLRTAGAT 273
Cdd:TIGR01356 117 QLGAEIsslEGGGSLPLTISGPLPGGIVYISGSASSQYKSALLLAAPALQAVgITIVGEPLKsrpYIEITLDLLGSFGVE 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 274 VT-TGENEFRVVQEGRPESVDFVTLPYPGFATdlqpFAIALSAVSAGTSMItENLFE----ARFRFIEEMVRLGADARTD 348
Cdd:TIGR01356 197 VErSDGRKIVVPGGQKYGPQGYDVPGDYSSAA----FFLAAAAITGGRVTL-ENLGInptqGDKAIIIVLEEMGADIEVE 271
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2267612541 349 GHHAVVRGVERLSSAPVWASD-IRAGAGLVLAGLCADGATEVYEIFHI-----ERgYPGFVENLRKLGATVE 414
Cdd:TIGR01356 272 EDDLIVEGASGLKGIKIDMDDmIDELPTLAVLAAFAEGVTRITGAEELrvkesDR-IAAIAEELRKLGVDVE 342
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
37-414 |
2.17e-12 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 68.25 E-value: 2.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 37 EGTTTITNCPEILDVPLMADVLRSLGceVTIEGDVATITTPAELNHRADSEA--MGK----LRasvcvlgPLVGrckraV 110
Cdd:PRK02427 37 EGETTITNLLRSEDTLATLNALRALG--VEIEDDEVVVEGVGGGGLKEPEDVldCGNsgttMR-------LLTG-----L 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 111 VAL-PG-----GDA-IGSRPLDMHQSGLRKLGAH-SEIEHGC---VVAEAQGLHGAQVWLDFPSVGATENILMAAVLADG 179
Cdd:PRK02427 103 LALqPGevvltGDEsLRKRPMGRLLDPLRQMGAKiEGRDEGYlplTIRGGKKGGPIEYDGPVSSQFVKSLLLLAPLFAEG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 180 TTVIDnaAREPEI----VDICV-MLQQMGARIE---GAGTSTLTVHGVPELHPTEHRVIGDrIVGAT-WAFAAAMTRG-D 249
Cdd:PRK02427 183 DTETT--VIEPLPsrphTEITLrMLRAFGVEVEnveGWGYRRIVIKGGQRLRGQDITVPGD-PSSAAfFLAAAAITGGsE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 250 ITVRGVDPKHI---NLVLEKLRTAGATVTTGENEFRVVQEG----RPESVDFVTLPYPGfATDLQPfAIA-LSAVSAGTS 321
Cdd:PRK02427 260 VTITNVGLNSTqggKAIIDVLEKMGADIEIENEREGGEPVGdirvRSSELKGIDIDIPD-IIDEAP-TLAvLAAFAEGTT 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 322 MITeNLFEARF----RfIEEMV----RLGADA--RTDGhhAVVRGVERlssAPVWAS--DIRAGAGLVLAGLCADGATEV 389
Cdd:PRK02427 338 VIR-NAEELRVketdR-IAAMAtelrKLGAEVeeTEDG--LIITGGPL---AGVVDSygDHRIAMAFAIAGLAAEGPVTI 410
|
410 420
....*....|....*....|....*
gi 2267612541 390 YEIFHIERGYPGFVENLRKLGATVE 414
Cdd:PRK02427 411 DDPECVAKSFPDFFEDLASLGANIE 435
|
|
| PLN02338 |
PLN02338 |
3-phosphoshikimate 1-carboxyvinyltransferase |
37-283 |
3.49e-06 |
|
3-phosphoshikimate 1-carboxyvinyltransferase
Pssm-ID: 177972 [Multi-domain] Cd Length: 443 Bit Score: 48.98 E-value: 3.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 37 EGTTTITNCPEILDVPLMADVLRSLGCEVT---------IEGDVATITTPAELNHRAD------SEAMGKLRASVCVLGp 101
Cdd:PLN02338 36 EGTTVVDNLLDSDDIRYMLGALKTLGLNVEedsennravVEGCGGKFPVSGDSKEDVElflgnaGTAMRPLTAAVTAAG- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 102 lvgrcKRAVVALPGGDAIGSRPLDMHQSGLRKLGAHSE--IEHGC---VVAEAQGLHGAQVWLDfPSVGAT--ENILMAA 174
Cdd:PLN02338 115 -----GNASYVLDGVPRMRERPIGDLVDGLKQLGADVEctLGTNCppvRVNAAGGLPGGKVKLS-GSISSQylTALLMAA 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 175 VLADGTTVIdnaarepEIVDICV----------MLQQMGARIEGAGT--STLTVHGVPELHPTEHRVIGDRIVGATWAFA 242
Cdd:PLN02338 189 PLALGDVEI-------EIVDKLIsvpyvemtlkLMERFGVSVEHSDSwdRFFIKGGQKYKSPGNAYVEGDASSASYFLAG 261
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2267612541 243 AAMTRGDITVRGV-------DPKHINlVLEKLrtaGATVTTGENEFRV 283
Cdd:PLN02338 262 AAITGGTVTVEGCgttslqgDVKFAE-VLEKM---GAKVEWTENSVTV 305
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
171-414 |
6.35e-06 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 48.16 E-value: 6.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 171 LMAAVLADGTTVIDNAAR-EpeivDICVM---LQQMGARIEGAGTSTLTVHGVPE------------------------- 221
Cdd:COG0128 29 LLLAALAEGESTIRNLLEsD----DTLATleaLRALGAEIEELDGGTLRVTGVGGglkepdavldcgnsgttmrlltgll 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 222 -LHPTEHRVIGD--------------------------------RIVGATWA-------------------FAAAMTRGD 249
Cdd:COG0128 105 aLQPGEVVLTGDeslrkrpmgrlldplrqlgariesrgggylplTIRGGPLKggeyeipgsassqfksallLAGPLAEGG 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 250 ITVRGVDP----KHINLVLEKLRTAGATVTT-GENEFRVVQEGRPESVDFVTLPYPGFATdlqpFAIALSAVSAGTSMIT 324
Cdd:COG0128 185 LEITVTGEleskPYRDHTERMLRAFGVEVEVeGYRRFTVPGGQRYRPGDYTVPGDISSAA----FFLAAAAITGSEVTVE 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 325 ---ENLFEARFRFIEEMVRLGADARTDGHHAVVRGvERLSS-----------APVwasdiragagLVLAGLCADGATEVY 390
Cdd:COG0128 261 gvgLNSTQGDTGILDILKEMGADIEIENDGITVRG-SPLKGididlsdipdeAPT----------LAVLAAFAEGTTRIR 329
|
330 340
....*....|....*....|....*....
gi 2267612541 391 EIFHIeRGY-----PGFVENLRKLGATVE 414
Cdd:COG0128 330 GAAEL-RVKesdriAAMATELRKLGADVE 357
|
|
| EPT_RTPC-like |
cd01553 |
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate ... |
231-409 |
2.49e-04 |
|
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats with a 4th slightly different domain inserted between the 2nd and 3rd repeat. They evidently share the same active site location, although the catalytic residues differ.
Pssm-ID: 238794 Cd Length: 211 Bit Score: 42.27 E-value: 2.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 231 GDRIVGATWAFAAAMTRGDITVRGVDPKHINL--------VLEKLRTA-GATVTTGE--NEFRVVQEGRPESVDFVTLPY 299
Cdd:cd01553 8 GGGQILRSFLVLAAISGGPITVTGIRPDRAKPgllrqhltFLKALEKIcGATVEGGElgSDRISFRPGTVRGGDVRFAIG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 300 P-GFATD-LQPFAIALsAVSAGTSMITENLF----------EARFRFIEEMVRLGADART------------DGHHAVVR 355
Cdd:cd01553 88 SaGSCTDvLQTILPLL-LFAKGPTRLTVTGGtdnpsappadFIRFVLEPELAKIGAHQEEtllrhgfypaggGVVATEVS 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2267612541 356 GVERLSSApvwasDIRAGAGLVLAGlcadGATEVYEIFHIERGYPGFVENLRKL 409
Cdd:cd01553 167 PVEKLNTA-----QLRQLVLPMLLA----SGAVEFTVAHPSCHLLTNFAVLEAL 211
|
|
| PRK11861 |
PRK11861 |
bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
15-364 |
3.78e-04 |
|
bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 183343 [Multi-domain] Cd Length: 673 Bit Score: 42.77 E-value: 3.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 15 GEVDVVGAKNSVLKLMAAALLAEGTTTITNCPEILDVPLMADVLRSLGCEVTIEGDVATI-TTPAELNHRADSEAMGKLR 93
Cdd:PRK11861 253 GTVRLPGSKSISNRVLLLAALAEGETTVTNLLDSDDTRVMLDALTKLGVKLSRDGGTCVVgGTRGAFTAKTADLFLGNAG 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 94 ASVcvlgplvgRCKRAVVALPGGD-------AIGSRPLDMHQSGLRKLGAHSEIEhGCVVAEAQGLHGAQVWLDFP--SV 164
Cdd:PRK11861 333 TAV--------RPLTAALAVNGGEyrihgvpRMHERPIGDLVDGLRQIGARIDYE-GNEGFPPLRIRPATISVDAPirVR 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 165 GATENILMAAVL--------ADGTTVID---NAAREPEIVDICVMLQQMGARIEGAGTSTLTV-HGVPELHPTEHRVIGD 232
Cdd:PRK11861 404 GDVSSQFLTALLmtlplvkaKDGASVVEidgELISKPYIEITIKLMARFGVTVERDGWQRFTVpAGVRYRSPGTIMVEGD 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 233 RIVGATWAFAAAMTRGDITVRGVDPKHIN---LVLEKLRTAGATVTTGENEFRVVQEGR------PESVDFVTLPYPGfa 303
Cdd:PRK11861 484 ASSASYFLAAGALGGGPLRVEGVGRASIQgdvGFANALMQMGANVTMGDDWIEVRGIGHdhgrlaPIDMDFNLIPDAA-- 561
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2267612541 304 tdlqpFAIALSAVSAGTSMITENLFEARFRFIEEMVRLGADARTDGhHAVVRGVERLSSAP 364
Cdd:PRK11861 562 -----MTIAVAALFADGPSTLRNIGSWRVKETDRIAAMATELRKVG-ATVEEGADYLVVTP 616
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
171-281 |
2.13e-03 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 40.13 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2267612541 171 LMAAVLADGTTVIDNAAREPeivDICVM---LQQMGARIEgagTSTLTVHGVPELHPTEHRVIGD--------RIVgatw 239
Cdd:PRK02427 30 LLLAALAEGETTITNLLRSE---DTLATlnaLRALGVEIE---DDEVVVEGVGGGGLKEPEDVLDcgnsgttmRLL---- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2267612541 240 AFAAAMTRGDITVRGVD-----PkhINLVLEKLRTAGATVTTGENEF 281
Cdd:PRK02427 100 TGLLALQPGEVVLTGDEslrkrP--MGRLLDPLRQMGAKIEGRDEGY 144
|
|
| |
