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Concise Results
Standard Results
Full Results
Na+/H+ antiporter NhaA [Alcaligenes aquatilis]
Protein Classification
Na+/H+ antiporter NhaA ( domain architecture ID 10006841 )
Na+/H+ antiporter NhaA extrudes sodium in exchange for external protons
List of domain hits
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
29-443
1.65e-151
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 435.67
E-value: 1.65e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI EA L GG VV LLLAA TV ALIWANS SFSD SY S AL W HT QVT L EL G PWRFSQD L HF W V ND I LM TL FF LV VG M EI R RE IHD G A LS 108
Cdd:COG3004 6 RS EA A GG IL LLLAA VL ALIWANS PLAE SY E AL L HT PLG L GI G SLHLDLS L LH W I ND G LM AI FF FL VG L EI K RE LLV G E LS 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DW R S A M LPI C AAL AAITL PALIY A A M N P - D P KVLM GWAIP T ATDIAFA V GVLALLG RSL P P SLR I FLLALAI I DDL I AIL 187
Cdd:COG3004 86 SP R K A A LPI I AAL GGMVV PALIY L A F N A g T P EAAR GWAIP M ATDIAFA L GVLALLG SRV P A SLR V FLLALAI V DDL G AIL 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 188 I IA F FY SG GL DYS A F L I A GVGIVAVLG L QKM G IG S A W A Y VVP G AI LW FGM LK T G A H P TLAGV V L GMMS P V R ALPLPRKAR 267
Cdd:COG3004 166 V IA L FY TS GL SLL A L L L A AAALALLAL L NRR G VR S L W P Y LLL G VV LW YAV LK S G V H A TLAGV L L ALTI P A R PRVGGEEEA 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 268 H lnlelatklesqhdtheimytlqkmqlaqreil P P VQ R IPAF LHPWVAF I I M P V FA L ANAGVSL N GL D L n AA GAQSALF 347
Cdd:COG3004 246 E --------------------------------- S P LE R LEHA LHPWVAF L I L P L FA F ANAGVSL S GL S L - AA LTSPVTL 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 348 G V A IA L IV GKPLG VLLGT WL P V R LGL CT LPAG MN W SGVALI GLLAGIGFTMS I F V A N LAF AE P V LLDAAKLG V L C GSL AS 427
Cdd:COG3004 292 G I A LG L VL GKPLG IFGFS WL A V K LGL AR LPAG VS W RQLYGV GLLAGIGFTMS L F I A E LAF PD P E LLDAAKLG I L L GSL LA 371
410
....*....|....*.
gi 2240352573 428 A I LG LVWGLIVR RR YQ 443
Cdd:COG3004 372 A V LG YLLLRLRL RR KR 387
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
29-443
1.65e-151
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 435.67
E-value: 1.65e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI EA L GG VV LLLAA TV ALIWANS SFSD SY S AL W HT QVT L EL G PWRFSQD L HF W V ND I LM TL FF LV VG M EI R RE IHD G A LS 108
Cdd:COG3004 6 RS EA A GG IL LLLAA VL ALIWANS PLAE SY E AL L HT PLG L GI G SLHLDLS L LH W I ND G LM AI FF FL VG L EI K RE LLV G E LS 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DW R S A M LPI C AAL AAITL PALIY A A M N P - D P KVLM GWAIP T ATDIAFA V GVLALLG RSL P P SLR I FLLALAI I DDL I AIL 187
Cdd:COG3004 86 SP R K A A LPI I AAL GGMVV PALIY L A F N A g T P EAAR GWAIP M ATDIAFA L GVLALLG SRV P A SLR V FLLALAI V DDL G AIL 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 188 I IA F FY SG GL DYS A F L I A GVGIVAVLG L QKM G IG S A W A Y VVP G AI LW FGM LK T G A H P TLAGV V L GMMS P V R ALPLPRKAR 267
Cdd:COG3004 166 V IA L FY TS GL SLL A L L L A AAALALLAL L NRR G VR S L W P Y LLL G VV LW YAV LK S G V H A TLAGV L L ALTI P A R PRVGGEEEA 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 268 H lnlelatklesqhdtheimytlqkmqlaqreil P P VQ R IPAF LHPWVAF I I M P V FA L ANAGVSL N GL D L n AA GAQSALF 347
Cdd:COG3004 246 E --------------------------------- S P LE R LEHA LHPWVAF L I L P L FA F ANAGVSL S GL S L - AA LTSPVTL 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 348 G V A IA L IV GKPLG VLLGT WL P V R LGL CT LPAG MN W SGVALI GLLAGIGFTMS I F V A N LAF AE P V LLDAAKLG V L C GSL AS 427
Cdd:COG3004 292 G I A LG L VL GKPLG IFGFS WL A V K LGL AR LPAG VS W RQLYGV GLLAGIGFTMS L F I A E LAF PD P E LLDAAKLG I L L GSL LA 371
410
....*....|....*.
gi 2240352573 428 A I LG LVWGLIVR RR YQ 443
Cdd:COG3004 372 A V LG YLLLRLRL RR KR 387
Na_H_antiport_1
pfam06965 Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. ...
29-434
1.16e-150
Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.
Pssm-ID: 429217
Cd Length: 378
Bit Score: 432.98
E-value: 1.16e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI EA L GG VV LL L AA TV ALIWANS SFS DSY S ALWHT QVTLEL G PWRF S QD LH F W V ND I LM TL FF L VVG M EI R RE IHD G A LS 108
Cdd:pfam06965 5 RS EA A GG IL LL A AA VL ALIWANS PLA DSY E ALWHT PLGVGF G GLSL S LS LH H W I ND G LM AI FF F VVG L EI K RE LLV G E LS 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DW R S A M LP IC AAL AAITL PALIY A A M N PDPKVLM GWAIP T ATDIAFA V GVLALLG RSL P P SLR I FLLALAI I DDL I AIL I 188
Cdd:pfam06965 85 SP R K A A LP VI AAL GGMVV PALIY L A F N AGGPGAR GWAIP M ATDIAFA L GVLALLG KRV P A SLR V FLLALAI V DDL G AIL V 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 189 IA F FY SG GL DYS A F L I A GVGIVAV L G L QKM G IGSA W A Y VVP G AI LW FGM LK T G A H P T L AGV V L GMMS P V R ALPLP rkarh 268
Cdd:pfam06965 165 IA L FY TS GL SLL A L L A A AAILAVL L L L NRL G VRRL W P Y LLL G VV LW VAV LK S G V H A T I AGV L L ALLI P A R PPARE ----- 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 269 lnlelatklesqhdtheimytlqkmqla Q RE ILP P VQ R IPAF LHPWVAF I I M P V FALANAGVSL N G LD L N A AGAQSALF G 348
Cdd:pfam06965 240 ---------------------------- S RE AIS P LE R LEHA LHPWVAF L I L P L FALANAGVSL S G SG L G A LLTSPVTL G 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 349 V A IA L IV GKPLG VLLGT WL P V R LGL CT LP A G MN W SGVALI GLLAGIGFTMS I F V A N LAF A - E PV LLD A AKLG V L C GSL AS 427
Cdd:pfam06965 292 I A LG L VL GKPLG IFGFS WL A V K LGL AR LP E G VT W RQLLGV GLLAGIGFTMS L F I A E LAF D d E LE LLD E AKLG I L L GSL LA 371
....*..
gi 2240352573 428 A I LG LVW 434
Cdd:pfam06965 372 A V LG YLV 378
nhaA
PRK09560 pH-dependent sodium/proton antiporter; Reviewed
31-431
1.57e-112
pH-dependent sodium/proton antiporter; Reviewed
Pssm-ID: 236568
Cd Length: 389
Bit Score: 336.47
E-value: 1.57e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 31 EA L GG VV L LL AA TV A L I W ANS SF S DS Y SALW HT Q V TLEL G PWRFSQD L HF W V ND I LM TL FFL V VG M EI R RE IHD G A LS D W 110
Cdd:PRK09560 12 EA A GG IL L MA AA AL A M I V ANS PL S EG Y FSFL HT P V AIQI G AFSIGKS L LH W I ND G LM AV FFL L VG L EI K RE LLE G Q LS S W 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 111 RSAM LP IC AA LAAITL PALIYAA M N - PD P KV L M GWAIP T ATDIAFA V GVLALLG RSL P P SL RI FLLALAIIDDL I AI L II 189
Cdd:PRK09560 92 QQRI LP AI AA VGGMVV PALIYAA F N y NN P ET L R GWAIP A ATDIAFA L GVLALLG KRV P V SL KV FLLALAIIDDL G AI V II 171
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 190 A F FY SGG L DYS A FLI A GVG I VAVLG L QKM G IGSAWA Y VVP GAILWF GM LK T G A H P TLAGVVL GMMS P VRA lplprkarhl 269
Cdd:PRK09560 172 A L FY TSD L SLP A LAL A AIA I AVLFL L NRL G VTKLTP Y LIV GAILWF AV LK S G V H A TLAGVVL AFCI P LKG ---------- 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 270 nlelatkle SQH D THEIMYT L QKM qlaqreilppvqripaf LHPWVAF I I M P V FA L ANAGVSL N G LD L NAAGAQSA L f G V 349
Cdd:PRK09560 242 --------- KKG D EESPLHH L EHA ----------------- LHPWVAF A I L P L FA F ANAGVSL A G IS L SSLTSPVP L - G I 294
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 350 A IA L IV GK PL GV LLGT WL P V R LGL CT LP A G M NW SGVALIGL L A GIGFTMS I F VAN LAF - A EPV LL DA A K LG V L C GSL A SA 428
Cdd:PRK09560 295 A LG L FL GK QV GV FGFS WL A V K LGL AK LP E G A NW KQIYGVSV L C GIGFTMS L F IGS LAF g A SEE LL TE A R LG I L L GSL L SA 374
...
gi 2240352573 429 ILG 431
Cdd:PRK09560 375 ILG 377
NhaA
TIGR00773 Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family ...
31-434
8.21e-97
Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273264
Cd Length: 373
Bit Score: 295.53
E-value: 8.21e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 31 E AL GG VV L LL AA TV A LIW ANS SF S DS Y SALW HT Q V T L EL G PWRFSQD L HF W V ND I LM TL FFL VV G M E IR RE IHD GALS DW 110
Cdd:TIGR00773 5 E SA GG IL L VI AA AL A MVM ANS AL S EW Y HDFL HT P V Q L QI G SFVIGKS L LH W I ND G LM AV FFL LI G L E VK RE LLE GALS SL 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 111 R S A ML P IC AA LAAITL PALIY A A M N - P DP KVLM GWAIP T ATDIAFA V GV L ALLG RSL P PS L R IFLLALAIIDDL I AI L II 189
Cdd:TIGR00773 85 R Q A IF P VI AA IGGMIA PALIY L A F N a N DP ITRE GWAIP A ATDIAFA L GV M ALLG KRV P LA L K IFLLALAIIDDL G AI V II 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 190 A F FY SGG L DYS A F L I A G V G I VAVLG L QKM G IGSAWA Y VVP G A ILWF GM LK T G A H P TLAGV VL G MMS P vralplprkarhl 269
Cdd:TIGR00773 165 A L FY TND L SMA A L L V A A V A I AVLAV L NRC G VRRLGP Y MLV G V ILWF AV LK S G V H A TLAGV II G FFI P ------------- 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 270 nlelatk L ESQHDTH eimytlqkmqlaqreilp P VQ R IPAF LHPWVA FI I M P V FA L ANAGVSL N G LD LN AA g AQSALF G V 349
Cdd:TIGR00773 232 ------- L KGKKGES ------------------ P LK R LEHV LHPWVA YL I L P L FA F ANAGVSL Q G VS LN GL - TSMLPL G I 285
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 350 AIA L IV GKPLG VL L GT W LP V R L G L CT LP A G M N WSGVALI G L L A GIGFTMSIF V A N LAF -- AE P V L LDA AKLG V L C GS LA S 427
Cdd:TIGR00773 286 ILG L LI GKPLG IF L FS W IA V K L K L AK LP E G I N FKQIFAV G V L C GIGFTMSIF I A S LAF gs VD P E L ITW AKLG I L L GS TT S 365
....*..
gi 2240352573 428 A I LG LV W 434
Cdd:TIGR00773 366 A V LG YS W 372
Name
Accession
Description
Interval
E-value
NhaA
COG3004 Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and ...
29-443
1.65e-151
Na+/H+ antiporter NhaA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442241
Cd Length: 387
Bit Score: 435.67
E-value: 1.65e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI EA L GG VV LLLAA TV ALIWANS SFSD SY S AL W HT QVT L EL G PWRFSQD L HF W V ND I LM TL FF LV VG M EI R RE IHD G A LS 108
Cdd:COG3004 6 RS EA A GG IL LLLAA VL ALIWANS PLAE SY E AL L HT PLG L GI G SLHLDLS L LH W I ND G LM AI FF FL VG L EI K RE LLV G E LS 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DW R S A M LPI C AAL AAITL PALIY A A M N P - D P KVLM GWAIP T ATDIAFA V GVLALLG RSL P P SLR I FLLALAI I DDL I AIL 187
Cdd:COG3004 86 SP R K A A LPI I AAL GGMVV PALIY L A F N A g T P EAAR GWAIP M ATDIAFA L GVLALLG SRV P A SLR V FLLALAI V DDL G AIL 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 188 I IA F FY SG GL DYS A F L I A GVGIVAVLG L QKM G IG S A W A Y VVP G AI LW FGM LK T G A H P TLAGV V L GMMS P V R ALPLPRKAR 267
Cdd:COG3004 166 V IA L FY TS GL SLL A L L L A AAALALLAL L NRR G VR S L W P Y LLL G VV LW YAV LK S G V H A TLAGV L L ALTI P A R PRVGGEEEA 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 268 H lnlelatklesqhdtheimytlqkmqlaqreil P P VQ R IPAF LHPWVAF I I M P V FA L ANAGVSL N GL D L n AA GAQSALF 347
Cdd:COG3004 246 E --------------------------------- S P LE R LEHA LHPWVAF L I L P L FA F ANAGVSL S GL S L - AA LTSPVTL 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 348 G V A IA L IV GKPLG VLLGT WL P V R LGL CT LPAG MN W SGVALI GLLAGIGFTMS I F V A N LAF AE P V LLDAAKLG V L C GSL AS 427
Cdd:COG3004 292 G I A LG L VL GKPLG IFGFS WL A V K LGL AR LPAG VS W RQLYGV GLLAGIGFTMS L F I A E LAF PD P E LLDAAKLG I L L GSL LA 371
410
....*....|....*.
gi 2240352573 428 A I LG LVWGLIVR RR YQ 443
Cdd:COG3004 372 A V LG YLLLRLRL RR KR 387
Na_H_antiport_1
pfam06965 Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. ...
29-434
1.16e-150
Na+/H+ antiporter 1; This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.
Pssm-ID: 429217
Cd Length: 378
Bit Score: 432.98
E-value: 1.16e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI EA L GG VV LL L AA TV ALIWANS SFS DSY S ALWHT QVTLEL G PWRF S QD LH F W V ND I LM TL FF L VVG M EI R RE IHD G A LS 108
Cdd:pfam06965 5 RS EA A GG IL LL A AA VL ALIWANS PLA DSY E ALWHT PLGVGF G GLSL S LS LH H W I ND G LM AI FF F VVG L EI K RE LLV G E LS 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DW R S A M LP IC AAL AAITL PALIY A A M N PDPKVLM GWAIP T ATDIAFA V GVLALLG RSL P P SLR I FLLALAI I DDL I AIL I 188
Cdd:pfam06965 85 SP R K A A LP VI AAL GGMVV PALIY L A F N AGGPGAR GWAIP M ATDIAFA L GVLALLG KRV P A SLR V FLLALAI V DDL G AIL V 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 189 IA F FY SG GL DYS A F L I A GVGIVAV L G L QKM G IGSA W A Y VVP G AI LW FGM LK T G A H P T L AGV V L GMMS P V R ALPLP rkarh 268
Cdd:pfam06965 165 IA L FY TS GL SLL A L L A A AAILAVL L L L NRL G VRRL W P Y LLL G VV LW VAV LK S G V H A T I AGV L L ALLI P A R PPARE ----- 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 269 lnlelatklesqhdtheimytlqkmqla Q RE ILP P VQ R IPAF LHPWVAF I I M P V FALANAGVSL N G LD L N A AGAQSALF G 348
Cdd:pfam06965 240 ---------------------------- S RE AIS P LE R LEHA LHPWVAF L I L P L FALANAGVSL S G SG L G A LLTSPVTL G 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 349 V A IA L IV GKPLG VLLGT WL P V R LGL CT LP A G MN W SGVALI GLLAGIGFTMS I F V A N LAF A - E PV LLD A AKLG V L C GSL AS 427
Cdd:pfam06965 292 I A LG L VL GKPLG IFGFS WL A V K LGL AR LP E G VT W RQLLGV GLLAGIGFTMS L F I A E LAF D d E LE LLD E AKLG I L L GSL LA 371
....*..
gi 2240352573 428 A I LG LVW 434
Cdd:pfam06965 372 A V LG YLV 378
nhaA
PRK09560 pH-dependent sodium/proton antiporter; Reviewed
31-431
1.57e-112
pH-dependent sodium/proton antiporter; Reviewed
Pssm-ID: 236568
Cd Length: 389
Bit Score: 336.47
E-value: 1.57e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 31 EA L GG VV L LL AA TV A L I W ANS SF S DS Y SALW HT Q V TLEL G PWRFSQD L HF W V ND I LM TL FFL V VG M EI R RE IHD G A LS D W 110
Cdd:PRK09560 12 EA A GG IL L MA AA AL A M I V ANS PL S EG Y FSFL HT P V AIQI G AFSIGKS L LH W I ND G LM AV FFL L VG L EI K RE LLE G Q LS S W 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 111 RSAM LP IC AA LAAITL PALIYAA M N - PD P KV L M GWAIP T ATDIAFA V GVLALLG RSL P P SL RI FLLALAIIDDL I AI L II 189
Cdd:PRK09560 92 QQRI LP AI AA VGGMVV PALIYAA F N y NN P ET L R GWAIP A ATDIAFA L GVLALLG KRV P V SL KV FLLALAIIDDL G AI V II 171
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 190 A F FY SGG L DYS A FLI A GVG I VAVLG L QKM G IGSAWA Y VVP GAILWF GM LK T G A H P TLAGVVL GMMS P VRA lplprkarhl 269
Cdd:PRK09560 172 A L FY TSD L SLP A LAL A AIA I AVLFL L NRL G VTKLTP Y LIV GAILWF AV LK S G V H A TLAGVVL AFCI P LKG ---------- 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 270 nlelatkle SQH D THEIMYT L QKM qlaqreilppvqripaf LHPWVAF I I M P V FA L ANAGVSL N G LD L NAAGAQSA L f G V 349
Cdd:PRK09560 242 --------- KKG D EESPLHH L EHA ----------------- LHPWVAF A I L P L FA F ANAGVSL A G IS L SSLTSPVP L - G I 294
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 350 A IA L IV GK PL GV LLGT WL P V R LGL CT LP A G M NW SGVALIGL L A GIGFTMS I F VAN LAF - A EPV LL DA A K LG V L C GSL A SA 428
Cdd:PRK09560 295 A LG L FL GK QV GV FGFS WL A V K LGL AK LP E G A NW KQIYGVSV L C GIGFTMS L F IGS LAF g A SEE LL TE A R LG I L L GSL L SA 374
...
gi 2240352573 429 ILG 431
Cdd:PRK09560 375 ILG 377
nhaA
PRK09561 sodium/proton antiporter NhaA;
29-434
2.65e-103
sodium/proton antiporter NhaA;
Pssm-ID: 181955
Cd Length: 388
Bit Score: 312.97
E-value: 2.65e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI EA L GG VV L LL AA TV A LIW ANS SF S DS Y SALWH T Q V T L EL G PWRFSQD L HF W V ND I LM TL FFL VV G M E IR RE IHD G A L S 108
Cdd:PRK09561 10 SS EA S GG IL L II AA AL A MLM ANS PT S GW Y QDFLE T P V Q L RV G ALEINKP L LL W I ND G LM AV FFL LI G L E VK RE LLE G S L A 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DW R S A M LP IC AA LAAITL PALIY AAM N - P DP KVLM GWAIP T ATDIAFA V GVLALLG RSL P PS L R IFLLALAIIDDL I AI L 187
Cdd:PRK09561 90 SR R Q A A LP VI AA IGGMLV PALIY LLF N y A DP VTRE GWAIP A ATDIAFA L GVLALLG SRV P VA L K IFLLALAIIDDL G AI V 169
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 188 IIA F FY SGG L DYSAFLI A G V G I VAVLG L QKM G IGSAWA Y VVP G AI LW FGM LK T G A H P TLAGV VL G MMS P VRALPLPRK A R 267
Cdd:PRK09561 170 IIA L FY TSD L SMVSLGV A A V A I AVLAV L NLC G VRRTSV Y ILV G VV LW VAV LK S G V H A TLAGV IV G FFI P LKEKHGRSP A E 249
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 268 H L nlelatkles Q H D theimytlqkmqlaqreilppvqripaf LHPWVAF I I M P V FA L ANAGVSL N G LD L NAAGAQSA L f 347
Cdd:PRK09561 250 R L ---------- E H G ---------------------------- LHPWVAF L I L P L FA F ANAGVSL Q G VT L DGLTSPLP L - 290
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 348 G V A IA L IV GKPLG VL L GT WL P V R L G L CT LP A G MNWSGVALI G L L A GIGFTMSIF V A N LAF -- AE P V L LDA AKLG V L C GSL 425
Cdd:PRK09561 291 G I A LG L FI GKPLG IF L FS WL A V K L K L AK LP E G TTFKQIYAV G V L C GIGFTMSIF I A S LAF gg VD P E L INY AKLG I L I GSL 370
....*....
gi 2240352573 426 A SA IL G LV W 434
Cdd:PRK09561 371 L SA VI G YS W 379
nhaA
PRK14855 pH-dependent sodium/proton antiporter; Provisional
29-448
1.68e-101
pH-dependent sodium/proton antiporter; Provisional
Pssm-ID: 237836
Cd Length: 423
Bit Score: 309.49
E-value: 1.68e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI EA LG G VV L LLA A TV A L IWANS SFSDS Y SA L W HT QVT L E LG P W RFSQD L HF WVND I LM TL FFL V VG M EI R RE IHD G A LS 108
Cdd:PRK14855 14 ES EA FA G LL L VGT A VA A F IWANS PWREG Y FT L Q HT HLA L S LG G W SLDLS L EH WVND G LM AV FFL L VG L EI K RE LLI G E LS 93
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DW R S A M L PIC AAL AAITL PA LI Y A A M N PDPKVLM GW AI P T ATDIAFA V GVLALLG RSL P PS L RI FL L ALAI I DDL I A I L I 188
Cdd:PRK14855 94 SP R Q A A L AVV AAL GGMLV PA AL Y T A L N AGGPGAS GW GV P M ATDIAFA L GVLALLG SRV P LG L KV FL T ALAI V DDL G A V L V 173
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 189 IA F FY SG GL DYS A F L I A GVGIVAV L GLQKM G IG S AWA Y V V P GA I LWF GM LK T G A HPT L AGV V L GMMS P V R A l PL P RKARH 268
Cdd:PRK14855 174 IA L FY TS GL NLL A L L L A ALTWALA L LAGRL G VT S LKI Y A V L GA L LWF FV LK S G L HPT V AGV L L ALAV P I R R - RD P LPYLA 252
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 269 LN L EL A TKLESQHDTHEIMYTLQKMQL AQ R eilp P VQ R IPAF LHPW VA F I I M PVFAL A NAGVS LN G LD L NAAG aqsal F G 348
Cdd:PRK14855 253 SL L DA A APGRPEVVGARLRDLEDLLER AQ S ---- P LH R LEHA LHPW ST F L I L PVFAL F NAGVS VS G GG L GTVS ----- L G 323
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 349 V AIA L IV GKPLGV LL G T WL P VRLGL CT LP AGM NW SGVALI GLLAGIGFTMS I F VA NLAFA EPV LL DA AKLGVL CG S LAS A 428
Cdd:PRK14855 324 V FLG L LL GKPLGV VG G A WL A VRLGL AS LP RRV NW LHMLGA GLLAGIGFTMS L F IS NLAFA DAA LL TQ AKLGVL AA S VLA A 403
410 420
....*....|....*....|
gi 2240352573 429 I LG LV W GLIVR R RYQRSASE 448
Cdd:PRK14855 404 L LG AG W LWWAV R GQPGEPND 423
NhaA
TIGR00773 Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family ...
31-434
8.21e-97
Na+/H+ antiporter NhaA; These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273264
Cd Length: 373
Bit Score: 295.53
E-value: 8.21e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 31 E AL GG VV L LL AA TV A LIW ANS SF S DS Y SALW HT Q V T L EL G PWRFSQD L HF W V ND I LM TL FFL VV G M E IR RE IHD GALS DW 110
Cdd:TIGR00773 5 E SA GG IL L VI AA AL A MVM ANS AL S EW Y HDFL HT P V Q L QI G SFVIGKS L LH W I ND G LM AV FFL LI G L E VK RE LLE GALS SL 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 111 R S A ML P IC AA LAAITL PALIY A A M N - P DP KVLM GWAIP T ATDIAFA V GV L ALLG RSL P PS L R IFLLALAIIDDL I AI L II 189
Cdd:TIGR00773 85 R Q A IF P VI AA IGGMIA PALIY L A F N a N DP ITRE GWAIP A ATDIAFA L GV M ALLG KRV P LA L K IFLLALAIIDDL G AI V II 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 190 A F FY SGG L DYS A F L I A G V G I VAVLG L QKM G IGSAWA Y VVP G A ILWF GM LK T G A H P TLAGV VL G MMS P vralplprkarhl 269
Cdd:TIGR00773 165 A L FY TND L SMA A L L V A A V A I AVLAV L NRC G VRRLGP Y MLV G V ILWF AV LK S G V H A TLAGV II G FFI P ------------- 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 270 nlelatk L ESQHDTH eimytlqkmqlaqreilp P VQ R IPAF LHPWVA FI I M P V FA L ANAGVSL N G LD LN AA g AQSALF G V 349
Cdd:TIGR00773 232 ------- L KGKKGES ------------------ P LK R LEHV LHPWVA YL I L P L FA F ANAGVSL Q G VS LN GL - TSMLPL G I 285
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 350 AIA L IV GKPLG VL L GT W LP V R L G L CT LP A G M N WSGVALI G L L A GIGFTMSIF V A N LAF -- AE P V L LDA AKLG V L C GS LA S 427
Cdd:TIGR00773 286 ILG L LI GKPLG IF L FS W IA V K L K L AK LP E G I N FKQIFAV G V L C GIGFTMSIF I A S LAF gs VD P E L ITW AKLG I L L GS TT S 365
....*..
gi 2240352573 428 A I LG LV W 434
Cdd:TIGR00773 366 A V LG YS W 372
nhaA
PRK14856 sodium/proton antiporter NhaA;
29-441
9.48e-89
sodium/proton antiporter NhaA;
Pssm-ID: 184858
Cd Length: 438
Bit Score: 277.06
E-value: 9.48e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 29 HI E AL GG VV L L L A A TV A LIW ANS SFSD SY S ALWHT QVTLEL G PWRFSQD LH F W VN D I LM T LFFL VV G M EI R RE IHD G A LS 108
Cdd:PRK14856 19 KS E SF GG IF L F L N A VL A MVV ANS FLKE SY F ALWHT PFGFQI G DFFIGFS LH N W ID D V LM A LFFL MI G L EI K RE LLF G E LS 98
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 109 DWRS A ML P IC AAL AAITL P A LIY AAM N P D PKVLM G WA IP T ATDIAFA V GV LA LLG RSL P PS L RI FL LA LA II DDL I AI LI 188
Cdd:PRK14856 99 SFKK A SF P VI AAL GGMIA P G LIY FFL N A D TPSQH G FG IP M ATDIAFA L GV IM LLG KRV P TA L KV FL IT LA VA DDL G AI VV 178
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 189 IA F FY SGG L DYSAF L I A GVGIVAVLG L QKMGIG S AWA Y VVP G AI LWF GMLKT G A H P T L A G VVL GM M S PV R alpl PR K ARH 268
Cdd:PRK14856 179 IA L FY TTN L KFAWL L G A LGVVLVLAV L NRLNVR S LIP Y LLL G VL LWF CVHQS G I H A T I A A VVL AF M I PV K ---- IP K DSK 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 269 l N L EL ATKLESQHD T H ------- E IMYT L QKMQLAQREILP P VQ R IPA FL H P WVAFI IMP V FA L ANAGVS LNG - LD L NAA 340
Cdd:PRK14856 255 - N V EL LELGKRYAE T S sgalltk E QQEI L HSIEEKASALQS P LE R LEH FL A P ISGYF IMP L FA F ANAGVS VDS s IN L EVD 333
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 341 G aqs A L F GV AIA L IV GKPLG VL L G T WLPVR L GLCTL P A G MN W SGVALI GLLAGIGFTMS I F VA NLAF -- AEPVLLDA AK L 418
Cdd:PRK14856 334 K --- V L L GV ILG L CL GKPLG IF L I T FISEK L KITAR P K G IS W WHILGA GLLAGIGFTMS M F IS NLAF ts EHKDAMEV AK I 410
410 420
....*....|....*....|...
gi 2240352573 419 GV L C GSL A S A I L G LVWGLIVRR R 441
Cdd:PRK14856 411 AI L L GSL I S G I I G ALYLFALDK R 433
nhaA
PRK14854 pH-dependent sodium/proton antiporter; Provisional
31-442
4.36e-66
pH-dependent sodium/proton antiporter; Provisional
Pssm-ID: 184856
Cd Length: 383
Bit Score: 216.63
E-value: 4.36e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 31 E AL GG VV L LL AA TV A LIWA NS SFSDS Y SA L WHTQ V T L ELGPWRFSQD L HF W V ND I LM TLF FL VV G M EI R REI HD G A LS DW 110
Cdd:PRK14854 9 E LI GG LI L FS AA LL A IVVN NS PLASY Y AM L ETIN V K L GIENLVIDKN L MH W I ND G LM AIY FL YI G L EI K REI IV G T LS KP 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 111 RSAML P IC AA L A AITL P A LIY AAM N P D P KV LM GWAIP T ATDIAF AV G V LALLG RSL P PS L RIFLLAL AI I DD LI AI L IIA 190
Cdd:PRK14854 89 SNIIT P AI AA F A GLAM P S LIY LSI N H D I KV IN GWAIP S ATDIAF TL G I LALLG TRV P AK L KLLVITI AI F DD IA AI A IIA 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 191 F FY SGG L DYSAFLIAGVG I V A VLGLQKM - G I GSAWA YVV P G AIL WF GML K T G A H P TLAG VVLGMMS P V R alplprkarhl 269
Cdd:PRK14854 169 I FY TKS L SLLSLSLGTLF I L A MIICNRI f K I NRSSV YVV L G FFA WF CTI K S G V H A TLAG FTTALCI P F R ----------- 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 270 nlelatkl E SQH D T heimytlqkmqlaqreilp P VQRIPAF LHPW VAFI I M PVFA L ANAG V S LN G LDLNAA g AQSALF G V 349
Cdd:PRK14854 238 -------- E NDK D S ------------------- P ANFMEDS LHPW IIYF I L PVFA F ANAG I S FS G ISFSIL - FEPITL G I 289
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2240352573 350 AIA L I VGK P LG VLLGTWLPVR L GLCT L PAGMNWSGVAL I G LL A GIGFTMS I F VAN LAF AEPV LL D A A K L GV LC GS LA S AI 429
Cdd:PRK14854 290 ILG L F VGK Q LG IFSILAVFKK L KWFK L GESFSNLQLYG I S LL C GIGFTMS L F IGV LAF NDTH LL N A I K I GV VV GS VL S GF 369
410
....*....|....
gi 2240352573 430 L G - L V WGL IV RRRY 442
Cdd:PRK14854 370 F G y I V LRF IV TNPS 383
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
