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Conserved domains on  [gi|2178211352|ref|WP_234398999|]
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barstar family protein [Planococcus massiliensis]

Protein Classification

barstar family protein( domain architecture ID 10473924)

barstar family protein similar to Bacillus amyloliquefaciens Barstar, an intracellular inhibitor of the extracellular ribonuclease barnase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Barstar pfam01337
Barstar (barnase inhibitor);
40-112 6.46e-17

Barstar (barnase inhibitor);


:

Pssm-ID: 460165  Cd Length: 82  Bit Score: 70.67  E-value: 6.46e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178211352  40 RFDCKEW-DEGLFHKEVARKLDFPAYYGENLNAFSDCLSDlLINNTGILLIFTHYQSFLAKHPELAIEVLEIIQ 112
Cdd:pfam01337   1 TIDGAGVrDKADLLDAIARALGFPDYFGRNLDALYDCLTD-LSWAPGYVLVWEGADALRKALPEDFETLLDVLE 73
 
Name Accession Description Interval E-value
Barstar pfam01337
Barstar (barnase inhibitor);
40-112 6.46e-17

Barstar (barnase inhibitor);


Pssm-ID: 460165  Cd Length: 82  Bit Score: 70.67  E-value: 6.46e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178211352  40 RFDCKEW-DEGLFHKEVARKLDFPAYYGENLNAFSDCLSDlLINNTGILLIFTHYQSFLAKHPELAIEVLEIIQ 112
Cdd:pfam01337   1 TIDGAGVrDKADLLDAIARALGFPDYFGRNLDALYDCLTD-LSWAPGYVLVWEGADALRKALPEDFETLLDVLE 73
BarS COG2732
Barstar, RNAse (barnase) inhibitor [Transcription];
38-112 2.75e-14

Barstar, RNAse (barnase) inhibitor [Transcription];


Pssm-ID: 442038  Cd Length: 90  Bit Score: 64.17  E-value: 2.75e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2178211352  38 IIRFDCKEW-DEGLFHKEVARKLDFPAYYGENLNAFSDCLSDLLinNTGILLIFTHYQSFLAKHPELAIEVLEIIQ 112
Cdd:COG2732     1 TVVIDGSEIrDEEDFYRQLARALDFPDYFGRNLDALWDCLTGGV--ELPVELVWKNAEASRRRLGEDFEALIEVLE 74
Barstar_evA4336-like cd05141
Barstar_evA4336-like contains uncharacterized sequences similar to the uncharacterized, ...
 48-112 1.73e-12

Barstar_evA4336-like contains uncharacterized sequences similar to the uncharacterized, predicted RNAase inhibitor evA4336 found in Azoarcus sp. EvN1. This is a subfamily of the Barstar family of RNAase inhibitors. Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell. Barstar also binds and inhibits a ribonuclease called RNase Sa (produced by Streptomyces aureofaciens) which belongs to the same enzyme family as does barnase.


Pssm-ID: 240164  Cd Length: 81  Bit Score: 59.23  E-value: 1.73e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2178211352  48 EGLFHkEVARKLDFPAYYGENLNAFSDCLSDL-LINNTGILLIFTHYQSFLAKHPELAIEVLEIIQ 112
Cdd:cd05141    12 AALLD-ALAAALDFPSWFGHNWDALADCLTDLsWWPAEGYVLVLRDGDALRAADPEDFATLLEILR 76
 
Name Accession Description Interval E-value
Barstar pfam01337
Barstar (barnase inhibitor);
40-112 6.46e-17

Barstar (barnase inhibitor);


Pssm-ID: 460165  Cd Length: 82  Bit Score: 70.67  E-value: 6.46e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178211352  40 RFDCKEW-DEGLFHKEVARKLDFPAYYGENLNAFSDCLSDlLINNTGILLIFTHYQSFLAKHPELAIEVLEIIQ 112
Cdd:pfam01337   1 TIDGAGVrDKADLLDAIARALGFPDYFGRNLDALYDCLTD-LSWAPGYVLVWEGADALRKALPEDFETLLDVLE 73
BarS COG2732
Barstar, RNAse (barnase) inhibitor [Transcription];
38-112 2.75e-14

Barstar, RNAse (barnase) inhibitor [Transcription];


Pssm-ID: 442038  Cd Length: 90  Bit Score: 64.17  E-value: 2.75e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2178211352  38 IIRFDCKEW-DEGLFHKEVARKLDFPAYYGENLNAFSDCLSDLLinNTGILLIFTHYQSFLAKHPELAIEVLEIIQ 112
Cdd:COG2732     1 TVVIDGSEIrDEEDFYRQLARALDFPDYFGRNLDALWDCLTGGV--ELPVELVWKNAEASRRRLGEDFEALIEVLE 74
Barstar_evA4336-like cd05141
Barstar_evA4336-like contains uncharacterized sequences similar to the uncharacterized, ...
 48-112 1.73e-12

Barstar_evA4336-like contains uncharacterized sequences similar to the uncharacterized, predicted RNAase inhibitor evA4336 found in Azoarcus sp. EvN1. This is a subfamily of the Barstar family of RNAase inhibitors. Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell. Barstar also binds and inhibits a ribonuclease called RNase Sa (produced by Streptomyces aureofaciens) which belongs to the same enzyme family as does barnase.


Pssm-ID: 240164  Cd Length: 81  Bit Score: 59.23  E-value: 1.73e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2178211352  48 EGLFHkEVARKLDFPAYYGENLNAFSDCLSDL-LINNTGILLIFTHYQSFLAKHPELAIEVLEIIQ 112
Cdd:cd05141    12 AALLD-ALAAALDFPSWFGHNWDALADCLTDLsWWPAEGYVLVLRDGDALRAADPEDFATLLEILR 76
Barstar_like cd00489
Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus ...
 36-109 9.39e-09

Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the cell. Barstar also binds and inhibits a ribonuclease called RNase Sa (produced by Streptomyces aureofaciens) which belongs to the same enzyme family as does barnase.


Pssm-ID: 238273  Cd Length: 85  Bit Score: 49.65  E-value: 9.39e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2178211352  36 FEIIRFDCKEWDEglFHKEVARKLDFPAYYGENLNAFSDCLSDllINNTGILLIFTHYQSFLAKHPELAIEVLE 109
Cdd:cd00489     1 VVIDGEDIADWED--FHARLKKKLGFPDYYGHNLDALWDCLTG--LVEEPLVLRWRNLEHLKRLTPEDAESVLQ 70
Barstar cd05142
Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus ...
 47-77 4.21e-05

Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell. Barstar also binds and inhibits a ribonuclease called RNase Sa (produced by Streptomyces aureofaciens) which belongs to the same enzyme family as does barnase.


Pssm-ID: 240165  Cd Length: 87  Bit Score: 40.00  E-value: 4.21e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2178211352  47 DEGLFHKEVARKLDFPAYYGENLNAFSDCLS 77
Cdd:cd05142    11 SIEDLHQILKKELALPEYYGENLDALWDCLT 41
Barstar_AU1054-like cd05140
Barstar_AU1054-like contains uncharacterized sequences similar to the uncharacterized, ...
 52-79 5.06e-05

Barstar_AU1054-like contains uncharacterized sequences similar to the uncharacterized, predicted RNAase inhibitor AU1054 found in Burkholderia cenocepacia. This is a subfamily of the Barstar family of RNAase inhibitors. Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell. Barstar also binds and inhibits a ribonuclease called RNase Sa (produced by Streptomyces aureofaciens) which belongs to the same enzyme family as does barnase.


Pssm-ID: 240163  Cd Length: 86  Bit Score: 40.03  E-value: 5.06e-05
                          10        20
                  ....*....|....*....|....*...
gi 2178211352  52 HKEVARKLDFPAYYGENLNAFSDCLSDL 79
Cdd:cd05140    15 HELLKECLGFPGWYGCNWDAFWDAITGL 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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