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Conserved domains on  [gi|2169053343|ref|WP_232609969|]
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host cell division inhibitor Icd-like protein [Haemophilus parainfluenzae]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
phage_ICD_like super family cl41269
host cell division inhibitor Icd domain; Icd from temperate phage P1 inhibits cell division in ...
177-224 2.39e-19

host cell division inhibitor Icd domain; Icd from temperate phage P1 inhibits cell division in its host. Homologous sequence is found in many other proteins, often as the C-terminal region of what appears to be a much larger protein. Putative phage proteins that contain this domain may be designated "host cell division inhibitor Icd-like protein". See PMID: 8491703 for a description of Icd. Many proteins with this domain also have the Ash domain described by PF10554, which also occurs in phage.


The actual alignment was detected with superfamily member NF033153:

Pssm-ID: 467967  Cd Length: 48  Bit Score: 78.35  E-value: 2.39e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2169053343 177 YQFIFAAIRRTDLSNHLQKIRITADSERNARAKLAREFVLVLAGRINL 224
Cdd:NF033153    1 FTWRFAAVRRTDRTARPCVIRITADTEREARRQLARDYVLVFAARIPV 48
Phage_ASH super family cl11183
Ash protein family; This family was identified by Iyer and colleagues. It includes the Ash ...
82-158 4.45e-05

Ash protein family; This family was identified by Iyer and colleagues. It includes the Ash protein from bacteriophage P4.


The actual alignment was detected with superfamily member pfam10554:

Pssm-ID: 431354  Cd Length: 105  Bit Score: 41.42  E-value: 4.45e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2169053343  82 KVIASRGKLNYLSQANDSTPQNRAFFVRNIRTPKEYADFVLhinpiiLSMVERN-KPSMTgclPVMAVFHLVTFYRPT 158
Cdd:pfam10554   5 KSVAGRGNPNITKATVDATPSVFAFFVDEALTHPSNPAMDL------FSMVAQAgQPKGW---PVSFVAGYANPVWVT 73
 
Name Accession Description Interval E-value
phage_ICD_like NF033153
host cell division inhibitor Icd domain; Icd from temperate phage P1 inhibits cell division in ...
177-224 2.39e-19

host cell division inhibitor Icd domain; Icd from temperate phage P1 inhibits cell division in its host. Homologous sequence is found in many other proteins, often as the C-terminal region of what appears to be a much larger protein. Putative phage proteins that contain this domain may be designated "host cell division inhibitor Icd-like protein". See PMID: 8491703 for a description of Icd. Many proteins with this domain also have the Ash domain described by PF10554, which also occurs in phage.


Pssm-ID: 467967  Cd Length: 48  Bit Score: 78.35  E-value: 2.39e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2169053343 177 YQFIFAAIRRTDLSNHLQKIRITADSERNARAKLAREFVLVLAGRINL 224
Cdd:NF033153    1 FTWRFAAVRRTDRTARPCVIRITADTEREARRQLARDYVLVFAARIPV 48
Phage_ASH pfam10554
Ash protein family; This family was identified by Iyer and colleagues. It includes the Ash ...
82-158 4.45e-05

Ash protein family; This family was identified by Iyer and colleagues. It includes the Ash protein from bacteriophage P4.


Pssm-ID: 431354  Cd Length: 105  Bit Score: 41.42  E-value: 4.45e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2169053343  82 KVIASRGKLNYLSQANDSTPQNRAFFVRNIRTPKEYADFVLhinpiiLSMVERN-KPSMTgclPVMAVFHLVTFYRPT 158
Cdd:pfam10554   5 KSVAGRGNPNITKATVDATPSVFAFFVDEALTHPSNPAMDL------FSMVAQAgQPKGW---PVSFVAGYANPVWVT 73
 
Name Accession Description Interval E-value
phage_ICD_like NF033153
host cell division inhibitor Icd domain; Icd from temperate phage P1 inhibits cell division in ...
177-224 2.39e-19

host cell division inhibitor Icd domain; Icd from temperate phage P1 inhibits cell division in its host. Homologous sequence is found in many other proteins, often as the C-terminal region of what appears to be a much larger protein. Putative phage proteins that contain this domain may be designated "host cell division inhibitor Icd-like protein". See PMID: 8491703 for a description of Icd. Many proteins with this domain also have the Ash domain described by PF10554, which also occurs in phage.


Pssm-ID: 467967  Cd Length: 48  Bit Score: 78.35  E-value: 2.39e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2169053343 177 YQFIFAAIRRTDLSNHLQKIRITADSERNARAKLAREFVLVLAGRINL 224
Cdd:NF033153    1 FTWRFAAVRRTDRTARPCVIRITADTEREARRQLARDYVLVFAARIPV 48
Phage_ASH pfam10554
Ash protein family; This family was identified by Iyer and colleagues. It includes the Ash ...
82-158 4.45e-05

Ash protein family; This family was identified by Iyer and colleagues. It includes the Ash protein from bacteriophage P4.


Pssm-ID: 431354  Cd Length: 105  Bit Score: 41.42  E-value: 4.45e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2169053343  82 KVIASRGKLNYLSQANDSTPQNRAFFVRNIRTPKEYADFVLhinpiiLSMVERN-KPSMTgclPVMAVFHLVTFYRPT 158
Cdd:pfam10554   5 KSVAGRGNPNITKATVDATPSVFAFFVDEALTHPSNPAMDL------FSMVAQAgQPKGW---PVSFVAGYANPVWVT 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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