alpha/beta fold hydrolase [Cupriavidus necator]
Protein Classification
alpha/beta fold hydrolase( domain architecture ID 10191051)
alpha/beta fold hydrolase similar to Alcaligenes esterase 713 which does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class and shows low sequence similarity to other esterase and lipase enzymes, is active as a dimer and cleaves esters on halogenated cyclic compounds (its natural substrate is unknown)
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||
| Esterase_713_like-3 | cd12810 | Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
10-337 | 0e+00 | ||||||
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown. : Pssm-ID: 214009 Cd Length: 328 Bit Score: 587.26 E-value: 0e+00
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| Name | Accession | Description | Interval | E-value | ||||||
| Esterase_713_like-3 | cd12810 | Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
10-337 | 0e+00 | ||||||
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown. Pssm-ID: 214009 Cd Length: 328 Bit Score: 587.26 E-value: 0e+00
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| Name | Accession | Description | Interval | E-value | ||||||
| Esterase_713_like-3 | cd12810 | Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
10-337 | 0e+00 | ||||||
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown. Pssm-ID: 214009 Cd Length: 328 Bit Score: 587.26 E-value: 0e+00
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| Esterase_713_like | cd12806 | Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family ... |
13-334 | 1.35e-95 | ||||||
Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown. This enzyme is possibly exported from the cytosol to the periplasmic space. A large majority of sequences in this family have yet to be characterized. Pssm-ID: 214005 Cd Length: 261 Bit Score: 284.43 E-value: 1.35e-95
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| Esterase_713 | cd12807 | Novel bacterial esterase 713 that cleaves esters on halogenated cyclic compounds; This family ... |
10-335 | 5.47e-58 | ||||||
Novel bacterial esterase 713 that cleaves esters on halogenated cyclic compounds; This family contains proteins similar to a novel bacterial esterase (esterase 713) with the alpha/beta hydrolase fold that cleaves esters on halogenated cyclic compounds. This Alcaligenes esterase, however, does not contain the GXSXXG pentapeptide around the active site serine residue as seen in other esterase families. This enzyme is active as a dimer though its natural substrate is unknown. It has two distinct disulfide bridges; one formed between adjacent cysteines appears to facilitate the correct formation of the oxyanion cleft in the catalytic site. Esterase 713 also resembles human pancreatic lipase in its location of the acidic residue of the catalytic triad. It is possibly exported from the cytosol to the periplasmic space. A large majority of sequences in this family have yet to be characterized. Pssm-ID: 214006 Cd Length: 315 Bit Score: 189.84 E-value: 5.47e-58
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| Esterase_713_like-1 | cd12808 | Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
17-328 | 9.82e-50 | ||||||
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown. Pssm-ID: 214007 Cd Length: 309 Bit Score: 168.19 E-value: 9.82e-50
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| Esterase_713_like-2 | cd12809 | Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated ... |
16-334 | 2.93e-39 | ||||||
Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; This family contains uncharacterized proteins similar to a novel bacterial esterase (Alcaligenes esterase 713) with the alpha/beta hydrolase fold but does not contain the GXSXXG pentapeptide around the active site serine residue as commonly seen in other enzymes of this class. Esterase 713 shows negligible sequence homology to other esterase and lipase enzymes. It is active as a dimer and cleaves esters on halogenated cyclic compounds though its natural substrate is unknown. Pssm-ID: 214008 Cd Length: 280 Bit Score: 140.05 E-value: 2.93e-39
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