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Conserved domains on  [gi|2044897408|ref|WP_213541091|]
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TasA family protein [Vescimonas coprocola]

Protein Classification

M73 family metallopeptidase( domain architecture ID 709871)

M73 family metallopeptidase such as camelysin that has been shown to cleave proteins such as caseins, actin and collagen type I; includes Bacillus subtilis biofilm component TasA, a spore-associated protein with antibacterial activity

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_M73 super family cl46710
Camelysin metallo-endopeptidase;
6-116 9.83e-03

Camelysin metallo-endopeptidase;


The actual alignment was detected with superfamily member pfam12389:

Pssm-ID: 481050  Cd Length: 196  Bit Score: 36.96  E-value: 9.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044897408   6 STKRALLGSVMAMVLCLAMLVGATFAWFTDTASTGvNKIQAGNLDIEIQDEAGKAIDTLAwatkdgtafaedgktplweP 85
Cdd:pfam12389   1 SLKKKLGMGVATAALGLSLIGGGTFAYFSDSETTN-NTFAAGTLDLSVDPTVIIDVNNLK-------------------P 60

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2044897408  86 GCTYTlTPFQIVNKGNL-----ALKYKIVVTGLEGD 116
Cdd:pfam12389  61 GDTMT-REFKLLNNGTLdiakvLLETDYNVTDAKGD 95
 
Name Accession Description Interval E-value
Peptidase_M73 pfam12389
Camelysin metallo-endopeptidase;
6-116 9.83e-03

Camelysin metallo-endopeptidase;


Pssm-ID: 372085  Cd Length: 196  Bit Score: 36.96  E-value: 9.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044897408   6 STKRALLGSVMAMVLCLAMLVGATFAWFTDTASTGvNKIQAGNLDIEIQDEAGKAIDTLAwatkdgtafaedgktplweP 85
Cdd:pfam12389   1 SLKKKLGMGVATAALGLSLIGGGTFAYFSDSETTN-NTFAAGTLDLSVDPTVIIDVNNLK-------------------P 60

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2044897408  86 GCTYTlTPFQIVNKGNL-----ALKYKIVVTGLEGD 116
Cdd:pfam12389  61 GDTMT-REFKLLNNGTLdiakvLLETDYNVTDAKGD 95
 
Name Accession Description Interval E-value
Peptidase_M73 pfam12389
Camelysin metallo-endopeptidase;
6-116 9.83e-03

Camelysin metallo-endopeptidase;


Pssm-ID: 372085  Cd Length: 196  Bit Score: 36.96  E-value: 9.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044897408   6 STKRALLGSVMAMVLCLAMLVGATFAWFTDTASTGvNKIQAGNLDIEIQDEAGKAIDTLAwatkdgtafaedgktplweP 85
Cdd:pfam12389   1 SLKKKLGMGVATAALGLSLIGGGTFAYFSDSETTN-NTFAAGTLDLSVDPTVIIDVNNLK-------------------P 60

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2044897408  86 GCTYTlTPFQIVNKGNL-----ALKYKIVVTGLEGD 116
Cdd:pfam12389  61 GDTMT-REFKLLNNGTLdiakvLLETDYNVTDAKGD 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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