|
Name |
Accession |
Description |
Interval |
E-value |
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
1-393 |
0e+00 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 771.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 1 MTASTPKRALQTRIVQPDDVIPEGFRSFVPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGG 80
Cdd:PRK07050 1 MTASTPKRALQTRIVQPDDQIPPGFRSFVTPVARASTVVFPDLATMRALDWRQDVQWRYGLHATPTSLALAQRLAEIEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 81 THALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPG 160
Cdd:PRK07050 81 RHALLQPSGLAAISLVYFGLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 161 SVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARM 240
Cdd:PRK07050 161 SVTMEVPDVPAITAAARARGVVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 241 RCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFDAR 320
Cdd:PRK07050 241 RLGIGVSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDER 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2044561768 321 YSAEQIDRFVESLELFAIGWSWGGACSLAMPYDVASMRP-DWPHRGTLVRFYVGLEDEADLRADIERAMQATLG 393
Cdd:PRK07050 321 YSPAQVDAFVEALELFAIGWSWGGACSLAMPYDVASMRTaKWPHRGTLVRLYIGLEDEADLIADLEQALEAALA 394
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
10-390 |
3.65e-153 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 437.56 E-value: 3.65e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 10 LQTRIVQPDDVIPEGFRSFVPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSG 89
Cdd:COG0626 3 PATRAVHAGRDPDPQTGAVSPPIYLTSTFVFPSAEALAARFAGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFASG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 90 LAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDV 169
Cdd:COG0626 83 MAAISAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVVDI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 170 QAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVD 249
Cdd:COG0626 163 AAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAVLSPF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 250 DCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFDArySAEQIDRF 329
Cdd:COG0626 243 DAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKG--GREAARRF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2044561768 330 VESLELFAIGWSWGGACSLAMPYDVASM-------RPDWPHRGTLVRFYVGLEDEADLRADIERAMQA 390
Cdd:COG0626 321 LDALKLFTLAVSLGGVESLITHPATMTHrslppeeRAALGITDGLVRLSVGLEDVDDLIADLEQALAA 388
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
25-390 |
9.62e-119 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 349.56 E-value: 9.62e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 25 FRSFVPPVARASTVVFPDLATMRalvwHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAG 104
Cdd:TIGR01324 14 QGSVNPPLQRASTVLFDSHAAQR----RAKGELTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAVTNSILAFVKAG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 105 DDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTA 184
Cdd:TIGR01324 90 DHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAKAARNPGIVIM 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 185 IDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGaTITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVR 264
Cdd:TIGR01324 170 IDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIG-TVVANARTWDQLREHSYLMGQMVDADDAYTTLRGLRTLGVR 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 265 FDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFdARYSAEQIDRFVESLELFAIGWSWGG 344
Cdd:TIGR01324 249 LKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVL-QRLTQKQVHAFLDHLQLFGLGYSWGG 327
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 2044561768 345 ACSLAMPYDVA-SMRPDWP--HRGTLVRFYVGLEDEADLRADIERAMQA 390
Cdd:TIGR01324 328 YESLALCNQPElGHRPNIKrnLEGPLIRVHIGLENVDDLKADLKAGFEA 376
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
22-391 |
6.98e-113 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 335.24 E-value: 6.98e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 22 PEGFRSFV-PPVARASTVVFPDLATMRAlvwhDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGI 100
Cdd:PRK05967 24 PGDYHGFVnPPVVHASTVLFPDAETMAT----RGQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTVPFLGF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 101 VKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARG 180
Cdd:PRK05967 100 LSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAEAAHRHG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 181 IVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGaTITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPS 260
Cdd:PRK05967 180 AIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLG-TVSANEKCWPQLLEAHGTLGLCAGPDDTYQILRGLRT 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 261 MQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVF--DARYSAEQIDRFVESLELFAI 338
Cdd:PRK05967 259 MGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLaaGPEKGKAKAHAFLDALEIFGL 338
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2044561768 339 GWSWGGACSLAMPYDVASMR-PDWPHRGTLVRFYVGLEDEADLRADIERAMQAT 391
Cdd:PRK05967 339 GYSWGGYESLALHVKLGDRTvAKAPYAGPVIRLQIGLEDVPDLKADLERGFAAA 392
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
30-387 |
1.17e-108 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 324.38 E-value: 1.17e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 30 PPVARASTVVFPDLATMRALVWHDDNQ-WRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVL 108
Cdd:PRK09028 25 PPVFRASTVVFDTVAEMRHAAKNRANGeMFYGRRGTPTHFAFQAAIVELEGGAGTALYPSGAAAISNALLSFLKAGDHLL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 109 IPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNT 188
Cdd:PRK09028 105 MVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQDVPTLSRIAHEHDIVVMLDNT 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 189 FSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGaTITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAH 268
Cdd:PRK09028 185 WASPINSRPFEMGVDISIQAATKYIVGHSDVMLG-TATANEKHWDQLREHSYLMGQCTSPDDVYLAMRGLRTLGVRLAQH 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 269 SKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFDARYSaEQIDRFVESLELFAIGWSWGGACSL 348
Cdd:PRK09028 264 EKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKQGDP-KAVTALVEGMQHFKMGFSWGGFESL 342
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2044561768 349 AMP-YDVASMR--PDWPHRGTLVRFYVGLEDEADLRADIERA 387
Cdd:PRK09028 343 ILGvFGINKLRtaTNWDFSKPLIRLHIGLEDVDDLIADLEAG 384
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
29-387 |
3.09e-107 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 319.92 E-value: 3.09e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 29 VPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVL 108
Cdd:cd00614 4 APPIYQTSTFVFPSPAEAADLFALREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALLKAGDHVV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 109 IPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNT 188
Cdd:cd00614 84 ASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVVDNT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 189 FSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAH 268
Cdd:cd00614 164 FATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRMERH 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 269 SKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSvvFDARYSAEQIDRFVESLELFAIGWSWGGACSL 348
Cdd:cd00614 244 SENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFS--FELKGGLEAAKKFLNALKLFSLAVSLGGVESL 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 2044561768 349 AMPydVASM------RPDWPHRG---TLVRFYVGLEDEADLRADIERA 387
Cdd:cd00614 322 VEH--PASMthsqlpPEERAAAGitpGLVRLSVGIEDVEDLIADLEQA 367
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
30-385 |
8.35e-102 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 307.02 E-value: 8.35e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 30 PPVARASTVVFPDLATM-RALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVL 108
Cdd:PRK08114 26 SVIQRASSLVFDSVEAKkHATRNRANGELFYGRRGTLTHFSLQEAMCELEGGAGCALYPCGAAAVANAILAFVEQGDHVL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 109 IPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARG--IVTAID 186
Cdd:PRK08114 106 MTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITMEVHDVPAIVAAVRSVNpdAVIMID 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 187 NTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGaTITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFD 266
Cdd:PRK08114 186 NTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIG-TAVANARCWEQLRENSYLMGQMVDADTAYMTSRGLRTLGVRLR 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 267 AHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFDARYSAEQIDRFVESLELFAIGWSWGGAC 346
Cdd:PRK08114 265 QHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKKLTDEQLANYLDNFSLFSMAYSWGGFE 344
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 2044561768 347 SLAM---PYDVASMRP--DWPHRGTLVRFYVGLEDEADLRADIE 385
Cdd:PRK08114 345 SLILanqPEEIAAIRPagEVDFTGTLIRLHIGLEDVDDLIADLA 388
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
22-388 |
1.31e-97 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 295.68 E-value: 1.31e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 22 PEGFRSFVPPVARASTVVFPDLATMRALVWHddnqwRYGlhaTPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIV 101
Cdd:pfam01053 12 DPQTGAVSVPIYLTSTYVFDFAGEEGGYDYS-----RSG---NPTRDVLEERIAALEGGAAALAFSSGMAAITAAILALL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 102 KAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGI 181
Cdd:pfam01053 84 KAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAKKHGI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 182 VTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSM 261
Cdd:pfam01053 164 LVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLRGLKTL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 262 QVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSvvFDARYSAEQIDRFVESLELFAIGWS 341
Cdd:pfam01053 244 GLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLS--FELKGGLEAAKKFLDNLKLFSLAVS 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2044561768 342 WGGACSLA-MPYDV--ASMRP-DWPHRG---TLVRFYVGLEDEADLRADIERAM 388
Cdd:pfam01053 322 LGGVESLIsHPATMthASIPPeEREAAGitdDLIRLSVGIEDVDDLIADLKQAL 375
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
1-390 |
2.52e-57 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 192.22 E-value: 2.52e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 1 MTASTPKRALQTRIVQPDDviPEGFRSFVPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGG 80
Cdd:PRK05968 1 MNDGLDPFDLAALITAHDE--GNAFDAVVPPIFQTSLFTFDSYDEMEDVYAGEKVRPIYSRGDNPTVRAFEEMLAKLEGA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 81 THALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYgPNAD--FGNWLANdFGITVRGYDPLIGAGIAELIqPNTRLIWLEA 158
Cdd:PRK05968 79 EDARGFASGMAAISSTVLSFVEPGDRIVAVRHVY-PDAFrlFETILKR-MGVEVDYVDGRDEEAVAKAL-PGAKLLYLES 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 159 PGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGaTITANAELHAKLK-L 237
Cdd:PRK05968 156 PTSWVFELQDVAALAALAKRHGVVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAG-VVAGSKEHIARINaE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 238 ARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHAsfmrdFTGAGGLFSVVF 317
Cdd:PRK05968 235 AYPYLGAKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPPAG-----LSGTSGLFSFIF 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 318 DarysaEQID--RFVESLELFAIGWSWGGACSLAMPYDVASMRPDWP---HR----GTLVRFYVGLEDEADLRADIERAM 388
Cdd:PRK05968 310 R-----EGIDvrAFADALKLFRLGVSWGGHESLVVPAEVVLQQKAQPnsaARfgvsPRSVRLHVGLEGTEALWADLEQAL 384
|
..
gi 2044561768 389 QA 390
Cdd:PRK05968 385 AA 386
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
27-390 |
3.22e-57 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 191.78 E-value: 3.22e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 27 SFVPPVARASTVVFPDLATMRalvwhddNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDD 106
Cdd:PRK07811 30 AVNPPIYASSTFAQDGVGGLR-------GGYEYARTGNPTRTALEEQLAALEGGAYGRAFSSGMAATDCLLRAVLRPGDH 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 107 VLIPHNVYGPNADFGNWLANDFGItvrGYDPLIGAGIAEL---IQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVT 183
Cdd:PRK07811 103 IVIPNDAYGGTFRLIDKVFTRWGV---EYTPVDLSDLDAVraaITPRTKLIWVETPTNPLLSITDIAALAELAHDAGAKV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 184 AIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAklKLARMRCGIGV--SVDDCSLVLRSLPSM 261
Cdd:PRK07811 180 VVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDE--AFAFLQNGAGAvpGPFDAYLTLRGLKTL 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 262 QVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFdaRYSAEQIDRFVESLELFAIGWS 341
Cdd:PRK07811 258 AVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRL--AGGEEAARDFCARTKVFTLAES 335
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2044561768 342 WGGACSL-----AMPY-DVASMRPDWPhrGTLVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK07811 336 LGGVESLiehpsAMTHaSTAGSQLEVP--DDLVRLSVGIEDVADLLADLEQALGQ 388
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
56-388 |
5.86e-54 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 183.43 E-value: 5.86e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 56 QWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKaGDDVLIPHNVYGPNADFGNWLANDFGITVRGY 135
Cdd:PRK08064 45 KYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAISTAFLLLSK-GDHVLISEDVYGGTYRMITEVLSRFGIEHTFV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 136 DPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSG 215
Cdd:PRK08064 124 DMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKLAKAIGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAG 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 216 GSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIAD 295
Cdd:PRK08064 204 HSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCWLVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQT 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 296 CPGHASFMRDFTGAGGLFSvvFDARySAEQIDRFVESLELFAIGWSWGGACSL----------AMPYDVASMRPDWPhrg 365
Cdd:PRK08064 284 HLGFDIQQSQATSAGAVLS--FTLQ-SEEAVRQFVSHVKLPVFAVSLGAVESIlsypakmshaAMPKEERDERGITD--- 357
|
330 340
....*....|....*....|...
gi 2044561768 366 TLVRFYVGLEDEADLRADIERAM 388
Cdd:PRK08064 358 GLLRLSVGLENVDDLIADFEQAL 380
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
58-391 |
6.61e-53 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 180.26 E-value: 6.61e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 58 RYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLaNDFGITVRGYDP 137
Cdd:PRK08574 46 KYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAISTLFFSLLKAGDRVVLPMEAYGTTLRLLKSL-EKFGVKVVLAYP 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 138 LIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGS 217
Cdd:PRK08574 125 STEDIIEAIKEGRTKLVFIETMTNPTLKVIDVPEVAKAAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHN 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 218 DVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCP 297
Cdd:PRK08574 205 DVVGGVAVAWSGEFLEELWEWRRRLGTIMQPFEAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDP 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 298 GHAS----FMRDFTGAgglfSVVFDARYSAEQIDRFVESLELFAIGWSWGGACSLAMpYDVASMRPDWPHRG-------- 365
Cdd:PRK08574 285 YHGVakrlFGKDLYGG----VVSFRVKGGRDAVLKFLRSLKLIKPSPSLGGVESLAT-YPVKSAASPIPEEDrkalgite 359
|
330 340
....*....|....*....|....*.
gi 2044561768 366 TLVRFYVGLEDEADLRADIERAMQAT 391
Cdd:PRK08574 360 DLVRLSVGLEDVEDLIEDLDQALGSI 385
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
23-390 |
3.57e-52 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 178.54 E-value: 3.57e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 23 EGFRSFVPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVK 102
Cdd:TIGR01328 17 DQFGALTPPIYQTSTFVFDSCEQGGNRFAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATSSGMGAIAATLLTILK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 103 AGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIV 182
Cdd:TIGR01328 97 AGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLIDMERVCRDAHSQGVK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 183 TAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGaTITANAELHAKLKLARMR--CGIGVSVDDCSLVLRSLPS 260
Cdd:TIGR01328 177 VIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAG-LICGKAELLQQIRMVGIKdmTGSVISPFDAWLILRGLKT 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 261 MQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSvvFDARYSAEQIDRFVESLELFAIGW 340
Cdd:TIGR01328 256 LNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMIT--FELKGGFAGAKKLLNNLKLIRLAV 333
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2044561768 341 SWGGACSLAMPYDVASMRPDWPHRGT-------LVRFYVGLEDEADLRADIERAMQA 390
Cdd:TIGR01328 334 SLGDAETLIQHPASMTHAVVPKEEREaagitdgMIRLSVGLEDADDLIADLKQALDA 390
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
56-390 |
6.16e-48 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 167.38 E-value: 6.16e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 56 QWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVyFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGY 135
Cdd:PRK06176 41 GYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAV-FSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTII 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 136 DPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSG 215
Cdd:PRK06176 120 DTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGG 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 216 GSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIAD 295
Cdd:PRK06176 200 HSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPT 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 296 CPGHASFMRDFTGAGGLFSVVFDarySAEQIDRFVESLELFAIGWSWGGACSL----------AMPydvASMRPDWPHRG 365
Cdd:PRK06176 280 HPNHELAKKQMRGFSGMLSFTLK---NDSEAVAFVESLKLFILGESLGGVESLvgipafmthaCIP---KEQREAAGIRD 353
|
330 340
....*....|....*....|....*
gi 2044561768 366 TLVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK06176 354 GLVRLSVGIEHEQDLLEDLEQAFAK 378
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
23-392 |
1.65e-47 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 166.22 E-value: 1.65e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 23 EGFRSFVPPVARASTVVFPDLATMRAlvwHDdnqwrYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVK 102
Cdd:PRK08045 18 EQYGCVVPPIHLSSTYNFTGFNEPRA---HD-----YSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 103 AGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIV 182
Cdd:PRK08045 90 PGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREAGAV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 183 TAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQ 262
Cdd:PRK08045 170 SVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLV 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 263 VRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFDArySAEQIDRFVESLELFAIGWSW 342
Cdd:PRK08045 250 PRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDG--DEQTLRRFLGGLSLFTLAESL 327
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2044561768 343 GGACSL---AMPYDVASMRPDWPHRG----TLVRFYVGLEDEADLRADIERAMQATL 392
Cdd:PRK08045 328 GGVESLishAATMTHAGMAPEARAAAgiseTLLRISTGIEDGEDLIADLENGFRAAN 384
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
27-390 |
2.79e-47 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 166.13 E-value: 2.79e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 27 SFVPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDD 106
Cdd:PRK07503 27 ALVPPVYLTATFAFPTAEYGAECFAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALASGMGAITATLWTLLRPGDE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 107 VLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAID 186
Cdd:PRK07503 107 VIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAAVAEIAHGAGAKVVVD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 187 NTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATItANAELHAKLKLARMR--CGIGVSVDDCSLVLRSLPSMQVR 264
Cdd:PRK07503 187 NTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVV-GGKALADRIRLEGLKdmTGAVMSPFDAFLLMRGLKTLALR 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 265 FDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLfsVVFDARYSAEQIDRFVESLELFAIGWSWGG 344
Cdd:PRK07503 266 MDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGM--IAFELKGGIAAGRRFMNALQLFARAVSLGD 343
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2044561768 345 ACSLAMpyDVASMR------PDWPHRGT---LVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK07503 344 AESLAQ--HPASMThstytpEERAEHGIsegLVRLSVGLEDVADILADLAQALDA 396
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
7-388 |
8.00e-47 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 164.24 E-value: 8.00e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 7 KRALQTRIVQPDDVIPEGFRSFVPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQ 86
Cdd:PRK06767 3 KKHMETALIHHGYTSEEHKGSLTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 87 PSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEV 166
Cdd:PRK06767 83 GSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 167 PDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGV 246
Cdd:PRK06767 163 IDLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 247 SVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQiadcpgHASFMRDFTGAGGLFSvvFDARYSAEQI 326
Cdd:PRK06767 243 APFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWYPE------GELASRQMKRGGGVIS--FSIKGGKEET 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2044561768 327 DRFVESLELFAIGWSWGGACSL-----AMPYDV--ASMRPDWPHRGTLVRFYVGLEDEADLRADIERAM 388
Cdd:PRK06767 315 QAFINDLHFITIAVSLGDTETLiqhpaTMTHAAipAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQAL 383
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
59-391 |
1.42e-46 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 163.24 E-value: 1.42e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 59 YGLHATPTSLALAQRLAEIEGGtHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRgYDPL 138
Cdd:PRK07582 45 YGRASNPTWRALEAALGELEGA-EALVFPSGMAAITAVLRALLRPGDTVVVPADGYYQVRALAREYLAPLGVTVR-EAPT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 139 igAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSD 218
Cdd:PRK07582 123 --AGMAEAALAGADLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSD 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 219 VLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPG 298
Cdd:PRK07582 201 LLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPA 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 299 HASFMRDFTGAGGLFSVVFDarySAEQIDRFVESLELFAIGWSWGGACSlampydVASMRPDW--PHRGTLVRFYVGLED 376
Cdd:PRK07582 281 HEVAARQMRRFGGLVSFELA---DAAAAERFVAASRLVVAATSFGGVHT------SADRRARWgdAVPEGFVRLSCGIED 351
|
330
....*....|....*
gi 2044561768 377 EADLRADIERAMQAT 391
Cdd:PRK07582 352 TDDLVADLERALDAL 366
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
57-389 |
1.10e-45 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 161.04 E-value: 1.10e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 57 WRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVyFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYD 136
Cdd:PRK07671 42 YEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAV-MMLFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVD 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 137 PLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGG 216
Cdd:PRK07671 121 TSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEKGLLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGH 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 217 SDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADC 296
Cdd:PRK07671 201 SDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLKTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSH 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 297 PGHASFMRDFTGAGGLFSvvFDARySAEQIDRFVESLELFAIGWSWGGACSL-AMPYDV--ASMRPDwpHR------GTL 367
Cdd:PRK07671 281 PNHELAKEQANGFGGMIS--FDVG-SEETANKVLERLQYFTLAESLGAVESLiSIPSQMthASIPAD--RRkelgitDGL 355
|
330 340
....*....|....*....|..
gi 2044561768 368 VRFYVGLEDEADLRADIERAMQ 389
Cdd:PRK07671 356 IRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
30-389 |
1.66e-45 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 161.31 E-value: 1.66e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 30 PPVARASTVVFPDLATMRalvwhddnQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLI 109
Cdd:PRK08776 33 PPIVLSSNFSFDGFGNKR--------QYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINLVLNALLQPGDTLVV 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 110 PHNVYGPNADFGNWLAND--FG-ITVRGYDPligAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAID 186
Cdd:PRK08776 105 PHDAYGGSWRLFNALAKKghFAlITADLTDP---RSLADALAQSPKLVLIETPSNPLLRITDLRFVIEAAHKVGALTVVD 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 187 NTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFD 266
Cdd:PRK08776 182 NTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLTLRGLRTLDARLR 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 267 AHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSvvFDARYSAEQIDRFVESLELFAIGWSWGGAC 346
Cdd:PRK08776 262 VHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLS--FELEGGEAAVRAFVDGLRYFTLAESLGGVE 339
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2044561768 347 SL-AMPYDV--ASMRPDWPHRG----TLVRFYVGLEDEADLRADIERAMQ 389
Cdd:PRK08776 340 SLiAHPASMthAAMTAEARAAAgisdGLLRLSVGIESAEDLLIDLRAGLA 389
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
25-390 |
6.32e-44 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 156.53 E-value: 6.32e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 25 FRSFVPPVARASTVVFPDLatmralvwHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAiMNVYFGIVKAG 104
Cdd:TIGR01329 15 YDASSMPIYQTATFKQPLA--------IENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAA-LDVITRLLNNG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 105 DDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTA 184
Cdd:TIGR01329 86 DEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHAQNALVV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 185 IDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVR 264
Cdd:TIGR01329 166 VDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGIKTLAIR 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 265 FDAHSKSALALAQWLKARPEIAAVLHPQIADCPG---HASFMRdftGAGGLFSVVFDarySAEQIDRFVESLELFAIGWS 341
Cdd:TIGR01329 246 IEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGfhlHFSQAK---GAGSVLSFETG---SVALSKRLVEATKLFSITVS 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 2044561768 342 WGGACSL-AMPYDV--ASMRPDWPHRGT----LVRFYVGLEDEADLRADIERAMQA 390
Cdd:TIGR01329 320 FGSVNSLiSMPCFMshASIPAEVREERGlpedLVRLSVGIEDVDDLISDLDIAFVT 375
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
65-390 |
7.04e-43 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 154.00 E-value: 7.04e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNAD-FGNWLANdFGITVRGYDPLIGAGI 143
Cdd:PRK08133 61 PTVTMFQERLAALEGAEACVATASGMAAILAVVMALLQAGDHVVSSRSLFGSTVSlFEKIFAR-FGIETTFVDLTDLDAW 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 144 AELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGA 223
Cdd:PRK08133 140 RAAVRPNTKLFFLETPSNPLTELADIAALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGA 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 224 TITANAELHAKLKLARMrCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFM 303
Cdd:PRK08133 220 VVGSKELMEEVFGFLRT-AGPTLSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAK 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 304 RDFTGAGGLFSvvFDARYSAEQIDRFVESLELFAIGWSWGGACS-LAMPYDVASMRPDWPHRGT------LVRFYVGLED 376
Cdd:PRK08133 299 RQQKGGGAIVS--FEVKGGREAAWRVIDATRLISITANLGDTKTtITHPATTTHGRLSPEARAAagitegLIRVAVGLED 376
|
330
....*....|....
gi 2044561768 377 EADLRADIERAMQA 390
Cdd:PRK08133 377 VADIKADLARGLAA 390
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
25-393 |
3.96e-42 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 151.97 E-value: 3.96e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 25 FRSFVPPVARASTVVFPDLAtmralvwhDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAImNVYFGIVKAG 104
Cdd:PRK08861 21 YHAVVPPIYLSTNYGFPAFG--------EVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSAL-NLWVSALLGP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 105 DDVLI-PHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVT 183
Cdd:PRK08861 92 DDLIVaPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQKAKAVGALV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 184 AIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAElHAKlKLARMRCGIGVSVD--DCSLVLRSLPSM 261
Cdd:PRK08861 172 AVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKE-HAE-ELAWWGNCIGATGTpfDSYMTLRGIRTL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 262 QVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSvvFDARYSAEQIDRFVESLELFAIGWS 341
Cdd:PRK08861 250 GARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLS--FEFAGSFEQLKVFVKALALFSLAES 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2044561768 342 WGGACSL-AMPydvASMrpdwPHRG-------------TLVRFYVGLEDEADLRADIERAMQATLG 393
Cdd:PRK08861 328 LGGVESLiCHP---ASM----THRAmgeealaeagvsqQLLRLSVGLEDAQDLIADLDQAFAKAAE 386
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
1-390 |
4.50e-42 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 152.49 E-value: 4.50e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 1 MTASTPKraLQTRIV----QPDDVipegFRSFVPPVARASTVVFPDLATMRALvwhddnqwrYGLHAT---------PTS 67
Cdd:COG2873 1 MTEKKYG--FETLALhagqEPDPT----TGARAVPIYQTTSYVFDDAEHAADL---------FALKEPgniytrimnPTT 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 68 LALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNAD-FGNWLAnDFGITVRGYDPLIGAGIAEL 146
Cdd:COG2873 66 DVLEKRIAALEGGVAALATASGQAAITLAILNLAEAGDHIVASSSLYGGTYNlFAHTLP-RLGIEVRFVDPDDPEAFEAA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 147 IQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATI- 225
Cdd:COG2873 145 IDPNTKAIFGETIGNPALDVLDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVd 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 226 ----------------TANAELH--------------AKLKLARMR-CGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALA 274
Cdd:COG2873 225 ggnfdwaangkfpeltEPDPSYHglvyteafgnaafiTKARVQLLRdLGAALSPFNAFLLLQGLETLSLRMERHVENALK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 275 LAQWLKARPEIAAVLHPQIADCPGHASFMRDFT-GAGGLFSvvFDARYSAEQIDRFVESLELFAIGWSWGGACSLAM-Py 352
Cdd:COG2873 305 VAEFLEAHPKVAWVNYPGLPSHPYHELAQKYLPkGAGGVLT--FGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIhP- 381
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 2044561768 353 dvASM---------------RPDwphrgtLVRFYVGLEDEADLRADIERAMQA 390
Cdd:COG2873 382 --ASTthsqlseeeqaaagvTPD------LIRLSVGIEDIDDIIADLDQALAA 426
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
58-391 |
1.41e-41 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 150.61 E-value: 1.41e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 58 RYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLAnDFGITVRGYDP 137
Cdd:PRK05939 40 TYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTLLRAGDHLVSSQFLFGNTNSLFGTLR-GLGVEVTMVDA 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 138 LIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGS 217
Cdd:PRK05939 119 TDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLYVVDNTMTSPWLFRPKDVGASLVINSLSKYIAGHG 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 218 DVLMGA-TITAN---------AELHAKLK-----LARMR------CGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALA 276
Cdd:PRK05939 199 NALGGAvTDTGLfdwsaypniFPAYRKGDpqqwgLTQIRkkglrdMGATLSSEAAHRIAIGAETLALRVDRSCSNALALA 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 277 QWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSvvFDARYSAEQIDrFVESLELFAIGWSWGGACSLAMP----- 351
Cdd:PRK05939 279 QFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLS--FELADGIDCFD-FLNRLKLVIKATHLGDTRTLVIPvapti 355
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2044561768 352 -YDV-ASMRPDWPHRGTLVRFYVGLEDEADLRADIERAMQAT 391
Cdd:PRK05939 356 yYEMgAERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
12-390 |
1.11e-39 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 145.43 E-value: 1.11e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 12 TRIVQPDDVIPEGFRSFVPPVARASTVVFPDlATMRALVWHDDNQ-WRYGLHATPTSLALAQRLAEIEGGTHALLQPSGL 90
Cdd:PRK06434 11 TRAVQSGELRDPRFGNVTTPIFETSTFVYPN-SEKEAYMDSTRGMpYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSGM 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 91 AAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYD-PLIGAGiaELIQPNTRLIWLEAPGSVTMEVPDV 169
Cdd:PRK06434 90 GAITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDtDRLNSL--DFDPSNYDLIYAESITNPTLKVPDI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 170 QAIAAAAKARGIVtaIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVD 249
Cdd:PRK06434 168 KNVSSFCHENDVI--VDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTLGSNPDPI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 250 DCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPqiaDCPGHASFMRDFtgaGGLFSvvFDARySAEQIDRF 329
Cdd:PRK06434 246 QAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYP---DTEIGKKVLRGF---GGMLS--FELR-SMEDVHKF 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2044561768 330 VESLELFAIGWSWGGACSL-AMPYDV--ASMRPDWPHR----GTLVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK06434 317 IRNLEIPMVAASLGGVESLiTLPVETshSSLSPEERERlgisDNLVRFSIGIEDIDDLIKDIENALSK 384
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
65-389 |
1.50e-37 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 139.07 E-value: 1.50e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMNVyFGIVKAGDDVLIPHNVYGPNA---DFG--NWlandfGITVRGYDPLI 139
Cdd:PRK08247 52 PTRGVLEQAIADLEGGDQGFACSSGMAAIQLV-MSLFRSGDELIVSSDLYGGTYrlfEEHwkKW-----NVRFVYVNTAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 140 GAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDV 219
Cdd:PRK08247 126 LKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAKIAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDV 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 220 LMGATITANAELHAklKLARMRCGIG--VSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPqiadcp 297
Cdd:PRK08247 206 LAGLVVAKGQELCE--RLAYYQNAAGavLSPFDSWLLIRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYP------ 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 298 ghasfmrdftGAGGLFSvvFDARySAEQIDRFVESLELFAIGWSWGGACSLaMPYDVASMRPDWPH-----RG---TLVR 369
Cdd:PRK08247 278 ----------GRGGMLS--FRLQ-DEEWVNPFLKSLKLITFAESLGGVESF-ITYPATQTHADIPEeiriaNGvcnRLLR 343
|
330 340
....*....|....*....|
gi 2044561768 370 FYVGLEDEADLRADIERAMQ 389
Cdd:PRK08247 344 FSVGIENVEDLIADLKQAFK 363
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
1-390 |
1.56e-36 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 137.88 E-value: 1.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 1 MTASTP-KRALQTRIVQP---------DDVIPEGfrSFVPPVARASTVVFP---------DLATMR---------ALVWH 52
Cdd:PRK07049 1 MTAPHPsKTHIGNRELHPetqmlnygyDPELSEG--AVKPPVFLTSTFVFRsaedgrdffDYVSGRkeppagegaGLVYS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 53 DDNQwryglhatPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADF-GNWLANdFGIT 131
Cdd:PRK07049 79 RFNH--------PNSEIVEDRLAVYEGAESAALFSSGMSAIATTLLAFVRPGDVILHSQPLYGGTETLlAKTFRN-FGVG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 132 VRGY-----DPLIGAGIAE-LIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGI------VTAIDNTFSAGLAFKPFA 199
Cdd:PRK07049 150 AVGFadglsEAAIGAAAEAaAAKGRVSLILIETPANPTNSLVDVAAVRRVADAIEArqghrpIIACDNTLLGPVFQKPLE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 200 HGVDISVQALTKYQSGGSDVLMGAtITANAELHAKLKLarMRCGIGVSVD--DCSLVLRSLPSMQVRFDAHSKSALALAQ 277
Cdd:PRK07049 230 HGADLSVYSLTKYVGGHSDLVAGA-VLGRKALIRQVRA--LRSAIGTQLDphSCWMLGRSLETLVLRMERANRNARAVAE 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 278 WLKARPEIAAV-LHPQI-ADCPGHASFMRDFTGAGGLFSvvFDARYSAEQIDRFVESLELFAIGWSWGGACSLA-MPydv 354
Cdd:PRK07049 307 FLRDHPKVEKLhYLPFLdPDSAYGAVYKRQCTGAGSTFS--FDIKGGQAAAFRFLNALQIFKLAVSLGGTESLAsHP--- 381
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 2044561768 355 ASMrpdwPHRG-------------TLVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK07049 382 ASM----THSGvpadvrerigvleSTIRLSIGIEHPDDLIADLAQALDA 426
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
25-389 |
6.29e-35 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 134.00 E-value: 6.29e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 25 FRSFVPPVARASTVVFPDlATmralvwhDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFgIVKAG 104
Cdd:PLN02509 101 FDAMSTPLYQTATFKQPS-AI-------ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTH-LIKNG 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 105 DDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTA 184
Cdd:PLN02509 172 EEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVL 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 185 IDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVR 264
Cdd:PLN02509 252 VDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALR 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 265 FDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSVVFDarySAEQIDRFVESLELFAIGWSWGG 344
Cdd:PLN02509 332 IEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITG---SVALSKHLVETTKYFSIAVSFGS 408
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2044561768 345 ACSL-AMP--YDVASMRPDWPH-RG---TLVRFYVGLEDEADLRADIERAMQ 389
Cdd:PLN02509 409 VKSLiSMPcfMSHASIPAEVREaRGlteDLVRISAGIEDVDDLISDLDIAFR 460
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
59-390 |
6.82e-35 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 132.56 E-value: 6.82e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 59 YGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYG-PNADFGNWLANdFGITVRGYDP 137
Cdd:PRK08249 58 YSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISNTLYTFLKPGDRVVSIKDTYGgTNKIFTEFLPR-MGVDVTLCET 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 138 LIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGS 217
Cdd:PRK08249 137 GDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIERLAAAAKKVGALVVVDNTFATPINQNPLALGADLVIHSATKFLSGHA 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 218 DVlMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCP 297
Cdd:PRK08249 217 DA-LGGVVCGSKELMEQVYHYREINGATMDPMSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHP 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 298 GHASFMRDFTGAGGLFSVVFDARYsaEQIDRFVESLELFAIGWSWGGACSLAMPYDVASMRPDWPHR-------GTLVRF 370
Cdd:PRK08249 296 NHEIAKAQMRGFGGILSFVLKGGM--DTVKRLLPKLRYAHRAANLGAVETIYGPARTTSHVENTLEEraalgipEGLVRI 373
|
330 340
....*....|....*....|
gi 2044561768 371 YVGLEDEADLRADIERAMQA 390
Cdd:PRK08249 374 SVGIEDTEDLIADLEQAFAH 393
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
7-388 |
3.81e-34 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 130.72 E-value: 3.81e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 7 KRALQTRIVQPDDVIPEGFRSFVPPVARASTVVFpDLATM--RALVWHDDNqWRYGLHATPTSLALAQRLAEIEGGTHAL 84
Cdd:PRK06234 6 KMGFATKAIHGGHIGDKQFGSLATPIYQTSTFIF-DSAEQggRRFAGEESG-YIYSRLGNPTSTEVENKLALLEGGEAAV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 85 LQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTM 164
Cdd:PRK06234 84 VAASGMGAISSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 165 EVPDVQAIA--AAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITaNAELHAKLKLARMR- 241
Cdd:PRK06234 164 KVTDIKAISniAHENNKECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVG-KEEFINQVKLFGIKd 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 242 -CGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDFTGAGGLFSvvFDAR 320
Cdd:PRK06234 243 mTGSVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMIS--FELK 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2044561768 321 YSAEQIDRFVESLELFAIGWSWGGACSL-----AM---PYdVASMRPDWPHRGTLVRFYVGLEDEADLRADIERAM 388
Cdd:PRK06234 321 GGVEEGKVVMNNVKLATLAVSLGDAETLiqhpaSMthsPY-TAEERKEAGISDGLVRLSVGLEDVDDIIADLKQAL 395
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
65-390 |
1.23e-29 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 117.61 E-value: 1.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMnVYFGIVKAGDDVLIPHNVYGpnADFgNWLAND-----FGITVRGYDPLI 139
Cdd:PRK07269 54 PTRAKLEETLAAIESADYALATSSGMSAIV-LAFSVFPVGSKVVAVRDLYG--GSF-RWFNQQekegrFHFTYANTEEEL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 140 GAGIAEliqpNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDV 219
Cdd:PRK07269 130 IAAIEE----DTDIVYIETPTNPLMVEFDIEKVAKLAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDV 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 220 LMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPqiadcpgh 299
Cdd:PRK07269 206 LAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYT-------- 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 300 asfmrdftGAGGLFSV-VFDarysAEQIDRFVESLELFAIGWSWGGACSLaMPYDVASMRPDWPHR--------GTLVRF 370
Cdd:PRK07269 278 --------GKGGMISFkVAD----ETRIPHILNSLKVFTFAESLGGVESL-ITYPTTQTHADIPAEvrhsygltDDLLRL 344
|
330 340
....*....|....*....|
gi 2044561768 371 YVGLEDEADLRADIERAMQA 390
Cdd:PRK07269 345 SIGIEDARDLIADLKQALEG 364
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
31-390 |
1.62e-29 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 118.30 E-value: 1.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 31 PVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIP 110
Cdd:PRK08134 30 PIHLTTSFVFRDSDHAAALFNLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQAALHLAIATLMGAGSHIVAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 111 HNVYGPNADFGNWLANDFGITVRGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFS 190
Cdd:PRK08134 110 SALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDIPTVAAIAHEAGVPLLVDSTFT 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 191 AGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATITAN------AELHAKLK--------------------LARMRC-- 242
Cdd:PRK08134 190 TPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVDGGrfdweaSGKFPELTepyagfhgmvfaeestvaafLLRARReg 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 243 ----GIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDF-TGAGGLFSvvF 317
Cdd:PRK08134 270 lrdfGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESHPDHALAKRLLpRGAGSVFS--F 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 318 DARYSAEQIDRFVESLELFAIGWSWGGACSLAM-PYDVASMRPDWPHRGT------LVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK08134 348 DLKGGRAAGRKFIESLKLFSHLANVGDARSLVIhPASTTHFRMDAAALAAagigegTIRLSIGLEDADDLIDDLKRALKA 427
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
53-393 |
3.68e-28 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 114.08 E-value: 3.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 53 DDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITV 132
Cdd:PRK07504 53 EDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAVTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIES 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 133 RGYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKY 212
Cdd:PRK07504 133 TLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKH 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 213 QSGGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQ 292
Cdd:PRK07504 213 IDGQGRCLGGVVLSDKAWIEEHLQDYFRHTGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPG 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 293 IADCPGHASFMRDFTGAGGLfsVVFDARYSAEQIDRFVESLELFAIGWSWGGACSLAM-PYDVASMRPDWPHRGTL---- 367
Cdd:PRK07504 293 RADHPQADIIAKQMTGGSTL--VAFELKGGKEAAFRFLNALKIVRISNNLGDAKSLIThPATTTHKNLSPEARAELgise 370
|
330 340
....*....|....*....|....*...
gi 2044561768 368 --VRFYVGLEDEADLRADIERAMQATLG 393
Cdd:PRK07504 371 gfLRLSAGLEDTDDLIEDLAAALKKVRA 398
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
65-391 |
4.79e-28 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 114.04 E-value: 4.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNAD-FGNWLANdFGITVRGYDPLIGAGI 143
Cdd:PRK05994 63 PTNAVLEERVAALEGGTAALAVASGHAAQFLVFHTLLQPGDEFIAARKLYGGSINqFGHAFKS-FGWQVRWADADDPASF 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 144 AELIQPNTRLIWLEA---PGSVtmeVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVL 220
Cdd:PRK05994 142 ERAITPRTKAIFIESianPGGT---VTDIAAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSM 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 221 MGATITA-----------------NAELHAkLKLAR--------MRC--------GIGVSVDDCSLVLRSLPSMQVRFDA 267
Cdd:PRK05994 219 GGIIVDGgtfdwsksgkypmlsepRPEYHG-LVLHEtfgnfafaIAArvlglrdlGPAISPFNAFLILTGIETLPLRMQR 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 268 HSKSALALAQWLKARPEIAAVLHPQIADCPGHAsFMRDFT--GAGGLFSVVFDARYSAEQidRFVESLELFAIGWSWGGA 345
Cdd:PRK05994 298 HSDNALAVAEWLKGHPKVSWVNYAGLPDDPYHA-LAQKYSpkGAGAVFTFGLKGGYEAGV--KLVSSLKLFSHLANIGDT 374
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2044561768 346 CSLAM-PYDV------------ASMRPDwphrgtLVRFYVGLEDEADLRADIERAMQAT 391
Cdd:PRK05994 375 RSLVIhPASTthrqltdeqkvaAGAGPD------VVRLSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
65-393 |
4.93e-26 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 108.45 E-value: 4.93e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNAdfgNWLANDF---GITVRGYDPLIGA 141
Cdd:PRK06084 58 PTNDVLEQRVAALEGGVGALAVASGMAAITYAIQTIAEAGDNIVSVAKLYGGTY---NLLAHTLpriGIETRFAAHDDIA 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 142 GIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLM 221
Cdd:PRK06084 135 ALEALIDERTKAVFCESIGNPAGNIIDIQALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIG 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 222 GATI------------------TANAELH--------------AKLKLARMR-CGIGVSVDDCSLVLRSLPSMQVRFDAH 268
Cdd:PRK06084 215 GIVVdsgkfpwaehkerfallnTPDPSYHgvtyteafgpaafiGRCRVVPLRnMGAALSPFNAFLILQGLETLALRMERH 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 269 SKSALALAQWLKARPEIAAVLHPQIADCPGHAsFMRDFTGAGGLFSVVFDARYSAEQIDRFVESLELFAIGWSWGGACSL 348
Cdd:PRK06084 295 TENALKVARYLQQHPQVAWVKYAGLPDHPEHE-LARRYMGGKPASILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSL 373
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2044561768 349 AMPYDVASMR----PDWPHRGT---LVRFYVGLEDEADLRADIERAMQATLG 393
Cdd:PRK06084 374 ACHPASTTHRqlndEELEKAGVsrdMVRLSIGIEHIDDIIADLAQALDASKG 425
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
65-390 |
1.01e-24 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 104.83 E-value: 1.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGY-DPLIGAGI 143
Cdd:PRK07812 69 PTQDVVEQRIAALEGGVAALLLASGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAW 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 144 AELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGA 223
Cdd:PRK07812 149 RAAVRPNTKAFFAETISNPQIDVLDIPGVAEVAHEAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGV 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 224 TI----------------TANAELH-------------AKLKLARMR-CGIGVSVDDCSLVLRSLPSMQVRFDAHSKSAL 273
Cdd:PRK07812 229 IVdggtfdwtqgrfpgftTPDPSYHgvvfaelgppayaLKARVQLLRdLGSAISPFNAFLIAQGLETLSLRIERHVANAQ 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 274 ALAQWLKARPEIAAVLHPQIADCPGHASFMRDF-TGAGGLFSvvFDARYSAEQIDRFVESLELFAIGWSWGGACSLAM-- 350
Cdd:PRK07812 309 RVAEFLEARDEVASVNYAGLPSSPWYERAKRLApKGTGAVLS--FELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIhp 386
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 2044561768 351 ---------PYDVAS--MRPDwphrgtLVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK07812 387 astthsqltPEEQLAtgVTPG------LVRLAVGIEGIDDILADLEAGFAA 431
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
37-334 |
9.09e-24 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 101.77 E-value: 9.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 37 TVVFPDlaTMRAL----VWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHN 112
Cdd:PLN02242 46 TVMEPD--TMRRMfsgeLGPDRDFYIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAISSVLLQLCSSGGHVVASNT 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 113 VYG-PNADFGNWLANDFGITVRGYDPLIGAGIAELIQPN-TRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFs 190
Cdd:PLN02242 124 LYGgTHALLAHFLPRKCNITTTFVDITDLEAVKKAVVPGkTKVLYFESISNPTLTVADIPELARIAHEKGVTVVVDNTF- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 191 AGLAFKPFAHGVDISVQALTKYQSGGSDVLMGAtITANAEL-HAKLKL---ARMRCGIGVSVDDCSLVLRSLPSMQVRFD 266
Cdd:PLN02242 203 APMVLSPARLGADVVVHSISKFISGGADIIAGA-VCGPAELvNSMMDLhhgALMLLGPTMNPKVAFELSERLPHLSLRMK 281
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2044561768 267 AHSKSALALAQWLKARPeiAAVLHPQIADCPGHA---SFMRDFTGAGGLFSVVFDarySAEQIDRFVESLE 334
Cdd:PLN02242 282 EHCRRAMEYAKRMKELG--LKVIYPGLEDHPQHAllkSMANKGYGFGGLLCLDMD---TEERANRLMRYLQ 347
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
65-391 |
7.81e-23 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 99.53 E-value: 7.81e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNAD-FGNWLANdFGITVRGYDPLIGAGI 143
Cdd:PRK08248 64 PTTDVFEKRIAALEGGIGALAVSSGQAAITYSILNIASAGDEIVSSSSLYGGTYNlFAHTLPK-LGITVKFVDPSDPENF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 144 AELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSG-------- 215
Cdd:PRK08248 143 EAAITDKTKALFAETIGNPKGDVLDIEAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGhgtsiggv 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 216 ----------GSDVLMGATiTANAELH----------------AKLKLARmRCGIGVSVDDCSLVLRSLPSMQVRFDAHS 269
Cdd:PRK08248 223 ivdsgkfdwkGSGKFPGLT-EPDPSYHglvytdavgeaayitkARVQLLR-DLGAALSPFNSFLLLQGLETLHLRMERHS 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 270 KSALALAQWLKARPEIAAVLHPQIADCPGHASFMRDF-TGAGGLfsVVFDARYSAEQIDRFVESLELFAIGWSWGGACSL 348
Cdd:PRK08248 301 ENALAVAKFLEEHEAVEWVSYPGLPSHPSYELAKKYLpKGQGAI--LTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSL 378
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2044561768 349 AM-PYDVASMRPDWPHRGT------LVRFYVGLEDEADLRADIERAMQAT 391
Cdd:PRK08248 379 IIhPASTTHQQLSEEEQLAagvtpgLVRLSVGTEAIDDILDDLRQAIRQS 428
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
58-389 |
1.09e-20 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 92.87 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 58 RYGlhaTPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGIT---VRG 134
Cdd:PRK07810 66 RYG---NPTVSMFEERLRLIEGAEACFATASGMSAVFTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVEtvfVDG 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 135 YDPligAGIAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQS 214
Cdd:PRK07810 143 EDL---SQWEEALSVPTQAVFFETPSNPMQSLVDIAAVSELAHAAGAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHID 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 215 GGSDVLMGATITANAELHAKLKLARMRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIA 294
Cdd:PRK07810 220 GQGRVLGGAILGDREYIDGPVQKLMRHTGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLP 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 295 DCPGHASFMRDFTGAGGLFSVVFDARYSA--EQIDRFVESLELFAIGWSWGGACSLAMPYDVASMRPDWPH-RG------ 365
Cdd:PRK07810 300 SHPQYDLAKRQMSGGGTVVTFELDAPEDAakKRAFEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEgRAaiglgd 379
|
330 340
....*....|....*....|....
gi 2044561768 366 TLVRFYVGLEDEADLRADIERAMQ 389
Cdd:PRK07810 380 GVVRLSVGLEDTDDLIADLDRALG 403
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
22-388 |
1.19e-19 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 90.11 E-value: 1.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 22 PEGFRSFVPPVARASTVVFPDLATMRALVWHDDNQWRYGLHATPTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIV 101
Cdd:PRK06702 18 PKNGEPRVLPLYQSTTYKYDTSDDLAALFNLEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAAIMLAVLNIC 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 102 KAGDDVLIPHNVYGPNADFGNWLANDFGITVRGYDPLIGAG-IAELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARG 180
Cdd:PRK06702 98 SSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNLTADeIVALANDKTKLVYAESLGNPAMNVLNFKEFSDAAKELE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 181 IVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGATI--------------------------------TAN 228
Cdd:PRK06702 178 VPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtngkypelvepdpsyhgvsyvqnfgAAA 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 229 AELHAKLKLARmRCGIGVSVDDCSLVLRSLPSMQVRFDAHSKSALALAQWLKARPEIAAVLHPQIaDCPGHASFMRDFTG 308
Cdd:PRK06702 258 YIVKARVQLLR-DYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGL-DSNENYSLAQKYLK 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 309 AGGLFSVVFDARYSAEQIDRFVESLELFAIGWSWGGACSLAMPYDVASMR----PDWPHRGT---LVRFYVGLEDEADLR 381
Cdd:PRK06702 336 KGASGVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRqlsaEDQRLAGVtsdLIRLSVGIEDVSDII 415
|
....*..
gi 2044561768 382 ADIERAM 388
Cdd:PRK06702 416 ADLEAAL 422
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
65-390 |
1.30e-19 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 89.93 E-value: 1.30e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 65 PTSLALAQRLAEIEGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPNADFGNWLANDFGITVRGY-DPLIGAGI 143
Cdd:PRK05613 69 PTVEALENRIASLEGGVHAVAFASGQAAETAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESW 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 144 AELIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAHGVDISVQALTKYQSGGSDVLMGA 223
Cdd:PRK05613 149 QAAVQPNTKAFFGETFANPQADVLDIPAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGV 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 224 TI---------------------TANAELHAkLKLA---------RMRCGI------GVSVDDCSLVLRSLPSMQVRFDA 267
Cdd:PRK05613 229 LIdggkfdwtverdgkpvfpyfvTPDPAYHG-LKYAdlgapafglKARAGLlrdtgaTLSPFNAWVTAQGLDTLSLRLER 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 268 HSKSALALAQWLKARPEIAAVLHPQIADCPGHASFMR---DFTGagglfSVV-FDARYSAEQIDRFVESLELFAIGWSWG 343
Cdd:PRK05613 308 HNENAIKVAEFLNNHEKVAKVNFAGLKDSPWYATKEKlglKYTG-----SVLsFDIKGGKDEAWAFIDALKLHSNLANIG 382
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2044561768 344 GACSLAM--------PYDVASMRPDWPHRGTlVRFYVGLEDEADLRADIERAMQA 390
Cdd:PRK05613 383 DVRSLVVhpattthsQSDEAGLARAGITQAT-VRLSVGIEDIDDIIADLEGGFAA 436
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
69-215 |
1.29e-04 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 42.37 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 69 ALAQRLAEI--EGGTHALLQPSGLAAIMNVYFGIVKAGDDVLIPHNVYGPN------ADFGNWLANDFGitvRGYDPLIG 140
Cdd:cd01494 4 ELEEKLARLlqPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRywvaaeLAGAKPVPVPVD---DAGYGGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2044561768 141 AGIAE--LIQPNTRLIWLEAPGSVTMEVPDVQAIAAAAKARGIVTAIDNTFSAGLAFKPFAH----GVDISVQALTKYQS 214
Cdd:cd01494 81 VAILEelKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGASPAPGVLipegGADVVTFSLHKNLG 160
|
.
gi 2044561768 215 G 215
Cdd:cd01494 161 G 161
|
|
| |
