|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
65-771 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 1346.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 65 RYQRSKQkkpidTTKPLGKVQAFLSKFTLSPRNPIRRFWRRYHIGKILFILVAMLVLTVGSYLFYIAKTTNVSDLQDALK 144
Cdd:NF038276 1 SYQRSKG-----YEEKAKKRPAWLSRIKPSPQNPIRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 145 ATTVIYDKEGNQAGSLSGQKGTYVELDAISDSLENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFGGGSTITQQLAKNA 224
Cdd:NF038276 76 ATTVIYDKDGKEAGSLSGQKGTYVELDAISDDLENAVIATEDRSFYKNSGINYKRFFLAILTAGRFGGGSTITQQLAKNA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 225 FLTQEQTVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIY 304
Cdd:NF038276 156 YLSQDQTIKRKAKEFFLALELTKKYSKKEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 305 NPIDNIRNATNRRNTVLANMVDDKKLSQADADSAAGVDMASRLDDTYQGTGDDYKYPSYFDAVIEEATKTYGLSEDEIVK 384
Cdd:NF038276 236 NPLYSIENATNRRDTVLQNMVDAGKIDQAQADEAAAVDMGSRLADTYEGKSDDYRYPSYFDAVINEAISKYGLSEKDIVN 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 385 NGYKIYTEMDANSQANMQQTYENTNLFPTSESDGSTAQSASVALDPTTGAVRGLVGRVGGTSDTTFRNFNYATQGKRSPG 464
Cdd:NF038276 316 NGYKIYTELDQNYQAGMQVTFDNTSLFPVSEYDGTSAQSASVALDPKTGGVRGLVGRVNSTENATFRSFNYATQSKRSPG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 465 STIKPLVVYAPALASGWSINKDLPNTPIDYNGYTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFG 544
Cdd:NF038276 396 STIKPLVVYSPAVASGWSIDKELPNTTQDYDGYKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFG 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 545 LNFDNVPEELGISLGGGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLG 624
Cdd:NF038276 476 LNMDKVDKELGVALGGGVTTNPLEMAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKRVISQSVADKMTSMMLG 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 625 TFSNGSAVNANYTGYTMAGKTGTVQAEFNKDLTSDQWVIGYTPDVVMTTWIGFDKTDESHYLTGASSGTASTIFSYIAAD 704
Cdd:NF038276 556 TFSNGTGVNANVYGYTMAGKTGTTETDFNPDLSSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASY 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 705 VLPNTPGTEFTVENAYAADGQTLDYTADPN------------DSRNSSNKSWTDKASDVVND--VKDQASSLWDKITDSF 770
Cdd:NF038276 636 ILPYTKGTEFTVENAYAQNGIAPVYTANETstetssesqdiiDDIRESAQNAVDSASKAVDDagIKEKAKSLWDSIVDWF 715
|
.
gi 1937373635 771 S 771
Cdd:NF038276 716 R 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
94-715 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 649.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 94 SPRNPIRRFWRRYHIGKILFILVAMLVLTVGSYLFYIAKTTNVSDLQD-ALKATTVIYDKEGNQAGSLSGQKGTYVELDA 172
Cdd:COG0744 2 AKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPEELEDlALPQTSTIYDRDGTLIATLGDENREWVPLDQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 173 ISDSLENAVIATEDRTFYENSGVNVKRFLLAIV----SMGRFGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKK 248
Cdd:COG0744 82 IPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVanltAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 249 YSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANMVDDK 328
Cdd:COG0744 162 YSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 329 KLSQADADSAAGVDMasRLDDTYQGTgDDYKYPSYFDAVIEEATKTYGlsEDEIVKNGYKIYTEMDANSQANMQQTYENT 408
Cdd:COG0744 242 YITQAEADAAKAEPL--TLVPPPNGA-AAGKYPYFVDYVRRELEELLG--EDDLYRGGLKIYTTLDPKLQKAAEKAVKNV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 409 nlFPTSESDGStaQSASVALDPTTGAVRGLvgrVGGTsDTTFRNFNYATQGKRSPGSTIKPLvVYAPALASGWSINKDLP 488
Cdd:COG0744 317 --LPEGKPGGL--QAALVVVDPKTGEVLAM---VGGR-DYGKSQFNRATQAKRQPGSTFKPF-VYAAALEQGYTPATTVD 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 489 NTPIDYNG--YTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFGLNfDNVPEELGISLgGGVTASP 566
Cdd:COG0744 388 DEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLAL-GTSEVSP 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 567 LQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLGTFSNGSAVNANYTGYTMAGKTG 646
Cdd:COG0744 466 LEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTG 545
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1937373635 647 TVQAefnkdlTSDQWVIGYTPDVVMTTWIGFDKTDESHYLTGasSGTASTIFSYIAADVLPNTPGTEFT 715
Cdd:COG0744 546 TTND------NRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTG--GSLPAPIWRDFMEAALEGLPVEDFP 606
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
164-708 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 591.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 164 KGTYVELDAISDSLENAVIATEDRTFYENSGVNVK---RFLLAIVSMGR-FGGGSTITQQLAKNAFLTQEQTVTRKAKEF 239
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKgigRAAVANITSGRvLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 240 FLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNT 319
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 320 VLANMVDDKKLSQADADSAAGVDMAsrlDDTYQGTGDDYKYPSYFDAVIEEATKTYGlseDEIVKNGYKIYTEMDANSQA 399
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQ---LYLQTKKSEQYKAPYFVDYVIQELEEEYG---EELYTGGLKIYTTLDLDAQK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 400 NMQQTYENTNLFPTsESDGSTAQSASVALDPTTGAVRGLVgrvgGTSDTTFRNFNYATQGKRSPGSTIKPLvVYAPALAS 479
Cdd:TIGR02074 235 AAEKVLNTGLRVAG-RRDGDDLQAALVAIDPDTGAVRALV----GGRDYGKSQFNRATQAKRQPGSTFKPF-VYAAALEK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 480 GWSINKDLPNTPIDYNG---YTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFGLNfDNVPEELGI 556
Cdd:TIGR02074 309 GLTPATIVNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGIT-SPLDPVLSL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 557 SLgGGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLGTFSNGSAVNANY 636
Cdd:TIGR02074 388 AL-GTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARL 466
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1937373635 637 TGYTMAGKTGTVQAefnkdlTSDQWVIGYTPDVVMTTWIGFDKTDeSHYLTGASSGTASTIFSYIAADVLPN 708
Cdd:TIGR02074 467 PGRPVAGKTGTTQN------WRDAWFVGYTPYYVTAVWVGYDDKK-TLGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
153-325 |
3.12e-79 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 251.67 E-value: 3.12e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 153 EGNQAGSLSGQKGTYVELDAISDSLENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFG----GGSTITQQLAKNAFLTQ 228
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGrivqGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 229 EQTVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPID 308
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 1937373635 309 NIRNATNRRNTVLANMV 325
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
110-700 |
5.22e-67 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 238.11 E-value: 5.22e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 110 KILFIL-VAMLVLTVGS----YLFYIAKTTNVSDLQDA-LKATTVIYDKEGNQAGSLSGQKGTYVELDAISDSLENAVIA 183
Cdd:PRK11636 5 KYLLILaVCCILLGAGSiyglYRYIEPQLPDVATLKDVrLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 184 TEDRTFYENSGVN----VKRFLLAIVSMGRFGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKKYSKQEILTMYL 259
Cdd:PRK11636 85 TEDSRFYEHHGVDpvgiFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 260 NNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANMVDDKKLSQADADSAa 339
Cdd:PRK11636 165 NKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQA- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 340 gvdMASRLDDTYQGTGDDYKYPSYFDAVIEEATKTYGlseDEIVKNGYKIYTEMDANSQANMQQTYENT----------- 408
Cdd:PRK11636 244 ---RSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYG---ENAYEDGYRVYTTITRKVQQAAQQAVRNNvldydmrhgyr 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 409 ------------------------------NLFP---TSES---------DGS------------------TAQ------ 422
Cdd:PRK11636 318 gpanvlwkvgesawdnkkitdtlkalptygPLLPavvTSANpqeatamlaDGSsvalpmegvrwarpyrsdTQQgptprk 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 423 -----------------------------SASVALDPTTGAVRGLVGRVggtsDTTFRNFNYATQGKRSPGSTIKPLvVY 473
Cdd:PRK11636 398 vtdvvqtgqqiwvrqvddawwlaqvpdvnSALVSINPQNGAVMALVGGF----DFNQSKFNRATQALRQVGSNIKPF-LY 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 474 APALASGW---SINKDLPNTPIDYNGYT-------PTNYGGveteDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKF 543
Cdd:PRK11636 473 TAAMDKGLtlaSMLNDVPISRWDAGAGSdwrpknsPPQYAG----PIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRF 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 544 GLNFDNVPEELGISLGGGvTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKK------------------ 605
Cdd:PRK11636 549 GFPAQNIVHTESLALGSA-SFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKvacpecdipviygdtqks 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 606 ------------------------------SKRVISQSVANQMTSMMLGT---FSNGSAVNANY--------TGYTMA-- 642
Cdd:PRK11636 628 nvlenddvenvatsqeqqnssvpmpqleqaNQALVAQNGAQEYAPHVINTplaFLIKSALNTNIfgepgwmgTGWRAGrd 707
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937373635 643 -------GKTGTVQAefnkdlTSDQWVIGYTPDVVMTTWIGFDKTDESHYLTGASSGTASTIFSY 700
Cdd:PRK11636 708 lkrrdigGKTGTTNS------SKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGY 766
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
65-771 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 1346.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 65 RYQRSKQkkpidTTKPLGKVQAFLSKFTLSPRNPIRRFWRRYHIGKILFILVAMLVLTVGSYLFYIAKTTNVSDLQDALK 144
Cdd:NF038276 1 SYQRSKG-----YEEKAKKRPAWLSRIKPSPQNPIRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 145 ATTVIYDKEGNQAGSLSGQKGTYVELDAISDSLENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFGGGSTITQQLAKNA 224
Cdd:NF038276 76 ATTVIYDKDGKEAGSLSGQKGTYVELDAISDDLENAVIATEDRSFYKNSGINYKRFFLAILTAGRFGGGSTITQQLAKNA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 225 FLTQEQTVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIY 304
Cdd:NF038276 156 YLSQDQTIKRKAKEFFLALELTKKYSKKEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 305 NPIDNIRNATNRRNTVLANMVDDKKLSQADADSAAGVDMASRLDDTYQGTGDDYKYPSYFDAVIEEATKTYGLSEDEIVK 384
Cdd:NF038276 236 NPLYSIENATNRRDTVLQNMVDAGKIDQAQADEAAAVDMGSRLADTYEGKSDDYRYPSYFDAVINEAISKYGLSEKDIVN 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 385 NGYKIYTEMDANSQANMQQTYENTNLFPTSESDGSTAQSASVALDPTTGAVRGLVGRVGGTSDTTFRNFNYATQGKRSPG 464
Cdd:NF038276 316 NGYKIYTELDQNYQAGMQVTFDNTSLFPVSEYDGTSAQSASVALDPKTGGVRGLVGRVNSTENATFRSFNYATQSKRSPG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 465 STIKPLVVYAPALASGWSINKDLPNTPIDYNGYTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFG 544
Cdd:NF038276 396 STIKPLVVYSPAVASGWSIDKELPNTTQDYDGYKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFG 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 545 LNFDNVPEELGISLGGGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLG 624
Cdd:NF038276 476 LNMDKVDKELGVALGGGVTTNPLEMAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKRVISQSVADKMTSMMLG 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 625 TFSNGSAVNANYTGYTMAGKTGTVQAEFNKDLTSDQWVIGYTPDVVMTTWIGFDKTDESHYLTGASSGTASTIFSYIAAD 704
Cdd:NF038276 556 TFSNGTGVNANVYGYTMAGKTGTTETDFNPDLSSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASY 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 705 VLPNTPGTEFTVENAYAADGQTLDYTADPN------------DSRNSSNKSWTDKASDVVND--VKDQASSLWDKITDSF 770
Cdd:NF038276 636 ILPYTKGTEFTVENAYAQNGIAPVYTANETstetssesqdiiDDIRESAQNAVDSASKAVDDagIKEKAKSLWDSIVDWF 715
|
.
gi 1937373635 771 S 771
Cdd:NF038276 716 R 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
94-715 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 649.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 94 SPRNPIRRFWRRYHIGKILFILVAMLVLTVGSYLFYIAKTTNVSDLQD-ALKATTVIYDKEGNQAGSLSGQKGTYVELDA 172
Cdd:COG0744 2 AKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPEELEDlALPQTSTIYDRDGTLIATLGDENREWVPLDQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 173 ISDSLENAVIATEDRTFYENSGVNVKRFLLAIV----SMGRFGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKK 248
Cdd:COG0744 82 IPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVanltAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 249 YSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANMVDDK 328
Cdd:COG0744 162 YSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 329 KLSQADADSAAGVDMasRLDDTYQGTgDDYKYPSYFDAVIEEATKTYGlsEDEIVKNGYKIYTEMDANSQANMQQTYENT 408
Cdd:COG0744 242 YITQAEADAAKAEPL--TLVPPPNGA-AAGKYPYFVDYVRRELEELLG--EDDLYRGGLKIYTTLDPKLQKAAEKAVKNV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 409 nlFPTSESDGStaQSASVALDPTTGAVRGLvgrVGGTsDTTFRNFNYATQGKRSPGSTIKPLvVYAPALASGWSINKDLP 488
Cdd:COG0744 317 --LPEGKPGGL--QAALVVVDPKTGEVLAM---VGGR-DYGKSQFNRATQAKRQPGSTFKPF-VYAAALEQGYTPATTVD 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 489 NTPIDYNG--YTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFGLNfDNVPEELGISLgGGVTASP 566
Cdd:COG0744 388 DEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLAL-GTSEVSP 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 567 LQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLGTFSNGSAVNANYTGYTMAGKTG 646
Cdd:COG0744 466 LEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGKTG 545
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1937373635 647 TVQAefnkdlTSDQWVIGYTPDVVMTTWIGFDKTDESHYLTGasSGTASTIFSYIAADVLPNTPGTEFT 715
Cdd:COG0744 546 TTND------NRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTG--GSLPAPIWRDFMEAALEGLPVEDFP 606
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
164-708 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 591.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 164 KGTYVELDAISDSLENAVIATEDRTFYENSGVNVK---RFLLAIVSMGR-FGGGSTITQQLAKNAFLTQEQTVTRKAKEF 239
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKgigRAAVANITSGRvLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 240 FLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNT 319
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 320 VLANMVDDKKLSQADADSAAGVDMAsrlDDTYQGTGDDYKYPSYFDAVIEEATKTYGlseDEIVKNGYKIYTEMDANSQA 399
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQ---LYLQTKKSEQYKAPYFVDYVIQELEEEYG---EELYTGGLKIYTTLDLDAQK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 400 NMQQTYENTNLFPTsESDGSTAQSASVALDPTTGAVRGLVgrvgGTSDTTFRNFNYATQGKRSPGSTIKPLvVYAPALAS 479
Cdd:TIGR02074 235 AAEKVLNTGLRVAG-RRDGDDLQAALVAIDPDTGAVRALV----GGRDYGKSQFNRATQAKRQPGSTFKPF-VYAAALEK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 480 GWSINKDLPNTPIDYNG---YTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFGLNfDNVPEELGI 556
Cdd:TIGR02074 309 GLTPATIVNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGIT-SPLDPVLSL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 557 SLgGGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLGTFSNGSAVNANY 636
Cdd:TIGR02074 388 AL-GTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARL 466
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1937373635 637 TGYTMAGKTGTVQAefnkdlTSDQWVIGYTPDVVMTTWIGFDKTDeSHYLTGASSGTASTIFSYIAADVLPN 708
Cdd:TIGR02074 467 PGRPVAGKTGTTQN------WRDAWFVGYTPYYVTAVWVGYDDKK-TLGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
100-716 |
5.80e-160 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 483.12 E-value: 5.80e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 100 RRFWRRyhIGKILFILVAMLVLTVGSYLFYIAKTT-NVSDLQDA-LKATTVIYDKEGNQAGSLSGQKGTYVELDAISDSL 177
Cdd:COG5009 1 MRLLKI--LLILLLLLLLLGALAVAGLYLYLSPDLpDVETLKDYqPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 178 ENAVIATEDRTFYENSGVNVKRFLLAIV----SMGRFGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKKYSKQE 253
Cdd:COG5009 79 INAFLAAEDKRFYEHPGVDPIGIARAAVvnlrTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 254 ILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANMVDDKKLSQA 333
Cdd:COG5009 159 ILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 334 DADSAagvdMASRLDDTYQGTGDDYKYPsYF-DAVIEEATKTYGlsEDEIVKNGYKIYTEMDANSQANMQQTYEN----- 407
Cdd:COG5009 239 EYEAA----KAEPLTARYHGASAEVDAP-YFaEMVRRELVERYG--EDALYTGGLKVYTTLDPRLQEAAEKALRDgllay 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 408 ----------TNLFPTSE--------------------------------SDGST------------------------- 420
Cdd:COG5009 312 drrhgyrgpeAHLDLAEEdwdealaevpdvgdlrpavvlevddksarvglRDGETgtlpleglkwarpyindnrrgpapk 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 421 -----------------------------AQSASVALDPTTGAVRGLvgrVGGTSdttFR--NFNYATQGKRSPGSTIKP 469
Cdd:COG5009 392 sasdvlkpgdvirvrpvadggwrlrqipeVQGALVALDPHTGAVLAL---VGGFD---FEqsKFNRATQAKRQPGSSFKP 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 470 LvVYAPALASGWS----INkDLP---NTPIDYNGYTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQK 542
Cdd:COG5009 466 F-VYAAALDNGYTpatiIN-DAPivfDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAER 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 543 FGLNfDNVPEELGISLG-GGVTasPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKK---------------- 605
Cdd:COG5009 544 FGIY-SKLPPNLSLALGsGEVT--PLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPAracedcdaaewdgaep 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 606 -----SKRVISQSVANQMTSMMLGTFSNGSAVNANYTGYTMAGKTGTvqaefnkdlTSDQ---WVIGYTPDVVMTTWIGF 677
Cdd:COG5009 621 rlpdpAEQVIDPRTAYQMTSMLRGVVQRGTGRRARALGRDIAGKTGT---------TNDSkdaWFVGFTPDLVAGVWVGF 691
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 1937373635 678 DktDES---HYLTGASsgTASTIFSYIAADVLPNTPGTEFTV 716
Cdd:COG5009 692 D--DPRslgRGETGGR--AALPIWIDFMKAALKDKPEKPFPV 729
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
158-690 |
1.10e-99 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 324.37 E-value: 1.10e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 158 GSLSGQKGT---YVELDAISDSLENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFG----GGSTITQQLAKNAFLTQEQ 230
Cdd:TIGR02071 137 AMLYSPNGEqrlFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGrtvqGGSTLTQQLVKNLFLSNER 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 231 TVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFG----NGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNP 306
Cdd:TIGR02071 217 SLWRKANEAYMALILDARYSKDRILELYLNEVYLGqsgdDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNP 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 307 IDNIRNATNRRNTVLANMVDDKKLSQADADSAAgvdmASRLDDTYQGtGDDYKYPSYFDAVIEEATKTYGlsedEIVKN- 385
Cdd:TIGR02071 297 WRNPDRALERRNLVLRLLQEQKIIDDEEYDMLS----ARPLGVQKKG-GIISRQPAFLQLVRRELRQKLG----DKVKDl 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 386 -GYKIYTEMDANSQANMQQTYENTNLFPTSESDGSTAQSASVALDPTTGAVRGLVgrvgGTSDTTFRNFNYATQGKRSPG 464
Cdd:TIGR02071 368 sGLRIFTTLDPVSQSAAEQAVQETIPALKKKKKLPDLEAAMVVTDRFTGEVRAMV----GGSDPQFAGFNRALQARRQIG 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 465 STIKPlVVYAPALAS--GWSINKDLPNTPIDYNG-----YTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGI 537
Cdd:TIGR02071 444 SLVKP-AVYLTALSQpdKYRLNTWIEDQPLSIKLsngqvWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVS 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 538 SYGQKFGLNFDNVPEELGISLGGGvTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQ 617
Cdd:TIGR02071 523 QTWNKLGINKDEIPPVPSMLLGAI-NLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYL 601
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937373635 618 MTSMMLGTFSNGSA--VNANYTGYTMAGKTGTvqaefNKDLTsDQWVIGYTPDVVMTTWIGFDKTDESHyLTGAS 690
Cdd:TIGR02071 602 TLYAMQQVVQRGTArsLGADFPSLSLAGKTGT-----TNDNR-DSWFAGIDGKEVTIIWLGRDDNGPTK-LTGAS 669
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
100-678 |
2.29e-81 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 276.33 E-value: 2.29e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 100 RRFWRRYHIGKILFILVAMLVLTVGSYLFYIakttnvsDLQDALKATTVIYDKEGNQAGSLSGQKGTY---VELDAISDS 176
Cdd:COG4953 4 ARLRRRRLLALLLALLLLALALWALDRLFPL-------PLLFAVPYSTVVLDRDGTLLRAFLAADGQWrlpVPLDEVSPR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 177 LENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFG----GGSTITQQLAKnafLT--QEQTVTRKAKEFFLSLELTKKYS 250
Cdd:COG4953 77 YLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGrivsGGSTLTMQVAR---LLepRPRTLSGKLRQILRALQLERRYS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 251 KQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANMVDDKKL 330
Cdd:COG4953 154 KDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 331 SQADADSAAGVDMASRLddtyqgtgddykYPSYFDA--VIEEATKTYGlsedeivkNGYKIYTEMDANSQANMQQ----- 403
Cdd:COG4953 234 DAEEAALALLEPVPARR------------RPLPQLAphLARRLLRQLP--------GGTRIRTTLDAGLQRRLERlvrry 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 404 -----TYENTNLfptsesdgstaqsASVALDPTTGAVRGLVGRVGGTsDTTFRNFNYATQGKRSPGSTIKPLvVYAPALA 478
Cdd:COG4953 294 vrrlkQNGIHNA-------------AVLVVDNRTGEVLAYVGSADFF-DASRQGQVDMVRALRSPGSTLKPF-LYGLALD 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 479 SGwSInkdLPNT-----PIDYNGYTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFGLN-FDNVPE 552
Cdd:COG4953 359 QG-LI---HPETlladvPTSFGGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRlLLPPAE 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 553 ELGISLG-GGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGdiiathskksKRVISQSVANQMTSMMLGTFSNGSA 631
Cdd:COG4953 435 HYGLSLIlGGAEVTLEELVGLYAALARGGEARPLRLLAGEPASPG----------RRLLSPGAAWLVRDILSDVPRPDGA 504
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 1937373635 632 VNANYTG--YTMAGKTGtvqaefnkdlTS----DQWVIGYTPDVVMTTWIG-FD 678
Cdd:COG4953 505 FGWRALDspPPIAWKTG----------TSygfrDAWAVGFTGRYTVGVWVGnPD 548
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
153-325 |
3.12e-79 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 251.67 E-value: 3.12e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 153 EGNQAGSLSGQKGTYVELDAISDSLENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFG----GGSTITQQLAKNAFLTQ 228
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGrivqGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 229 EQTVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPID 308
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 1937373635 309 NIRNATNRRNTVLANMV 325
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
137-735 |
3.43e-67 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 236.55 E-value: 3.43e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 137 SDLQDALKATTVIYDKEGNQAGSLSGQKGTY---VELDAISDSLENAVIATEDRTFYENSGVN----VKRFLLAIVSMGR 209
Cdd:TIGR02073 2 PPLLFHRPSSTVVLDRHGTLLRALLANDGQWrlpVPLEDISPKFLQALLLYEDKRFYWHPGVNplalLRAAWQNLTNGRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 210 FGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVD 289
Cdd:TIGR02073 82 VSGGSTLTMQLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 290 EAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANMVDDKKLSQADADSAAGVDMASRLDDTYQgtgddyKYPSYFDAVIE 369
Cdd:TIGR02073 162 EAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPALPEPLPQ------LAPHFALKLLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 370 EATKTYGlsedeivkngyKIYTEMDANSQANMQQTYENtNLFPTSESDGSTAqsASVALDPTTGAVRGLVGRVGGTSDtt 449
Cdd:TIGR02073 236 ARPEIAS-----------VIVSTLDADLQRRLEELARR-YLSALRPRGISNL--AILVVDNRSGAVLAYVGSADFFDD-- 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 450 fRNFNY--ATQGKRSPGSTIKPLvVYAPALASGwSINKD--LPNTPIDYNGYTPTNYGGVETEDVPMYQALANSYNIPAV 525
Cdd:TIGR02073 300 -SNSGQvdGVRAPRSPGSTLKPF-LYALALDDG-LLHPDslLKDVPLRFGDYAPENFDKTFHGPVPAREALARSLNIPAV 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 526 YLFNQIGIQKGISYGQKFGLN-FDNVPEELGISLG-GGVTASPLQMAQAYATFANGGEMNTAYFITkienasgdiiATHS 603
Cdd:TIGR02073 377 RLLERVGPPRFADFLRQAGLNlLKPKSDYYGLSLAlGGAEITLQDLANLYAMLANQGLSGPLRFLQ----------TDAK 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 604 KK-SKRVISQSVANQMTSMMLGTFSNGSAVNANY--TGYTMAGKTGTVQAefnkdlTSDQWVIGYTPDVVMTTWIG-FDK 679
Cdd:TIGR02073 447 RPeRERLLSPGAAWIVLDILKDRPRPDDTLPLSAlpTRLPLAWKTGTSYG------FRDAWAAGVSGRYTIGVWVGnFDG 520
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 1937373635 680 TDESHyLTGASsgTASTIFSYIaADVLPNTPGTEFTVENAYAADGQTLDYTADPND 735
Cdd:TIGR02073 521 KPNPG-FFGAA--AAAPLLFDI-LDALQASEASTLPRPLKEVPGCLVLGNLPILPC 572
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
110-700 |
5.22e-67 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 238.11 E-value: 5.22e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 110 KILFIL-VAMLVLTVGS----YLFYIAKTTNVSDLQDA-LKATTVIYDKEGNQAGSLSGQKGTYVELDAISDSLENAVIA 183
Cdd:PRK11636 5 KYLLILaVCCILLGAGSiyglYRYIEPQLPDVATLKDVrLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 184 TEDRTFYENSGVN----VKRFLLAIVSMGRFGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKKYSKQEILTMYL 259
Cdd:PRK11636 85 TEDSRFYEHHGVDpvgiFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 260 NNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANMVDDKKLSQADADSAa 339
Cdd:PRK11636 165 NKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQA- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 340 gvdMASRLDDTYQGTGDDYKYPSYFDAVIEEATKTYGlseDEIVKNGYKIYTEMDANSQANMQQTYENT----------- 408
Cdd:PRK11636 244 ---RSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYG---ENAYEDGYRVYTTITRKVQQAAQQAVRNNvldydmrhgyr 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 409 ------------------------------NLFP---TSES---------DGS------------------TAQ------ 422
Cdd:PRK11636 318 gpanvlwkvgesawdnkkitdtlkalptygPLLPavvTSANpqeatamlaDGSsvalpmegvrwarpyrsdTQQgptprk 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 423 -----------------------------SASVALDPTTGAVRGLVGRVggtsDTTFRNFNYATQGKRSPGSTIKPLvVY 473
Cdd:PRK11636 398 vtdvvqtgqqiwvrqvddawwlaqvpdvnSALVSINPQNGAVMALVGGF----DFNQSKFNRATQALRQVGSNIKPF-LY 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 474 APALASGW---SINKDLPNTPIDYNGYT-------PTNYGGveteDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKF 543
Cdd:PRK11636 473 TAAMDKGLtlaSMLNDVPISRWDAGAGSdwrpknsPPQYAG----PIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRF 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 544 GLNFDNVPEELGISLGGGvTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKK------------------ 605
Cdd:PRK11636 549 GFPAQNIVHTESLALGSA-SFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKvacpecdipviygdtqks 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 606 ------------------------------SKRVISQSVANQMTSMMLGT---FSNGSAVNANY--------TGYTMA-- 642
Cdd:PRK11636 628 nvlenddvenvatsqeqqnssvpmpqleqaNQALVAQNGAQEYAPHVINTplaFLIKSALNTNIfgepgwmgTGWRAGrd 707
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937373635 643 -------GKTGTVQAefnkdlTSDQWVIGYTPDVVMTTWIGFDKTDESHYLTGASSGTASTIFSY 700
Cdd:PRK11636 708 lkrrdigGKTGTTNS------SKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGY 766
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
159-698 |
1.63e-62 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 225.03 E-value: 1.63e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 159 SLSGQKGTYVELDAISDSLENAVIATEDRTFYENSGVN---VKRFLLAIVSMGR-FGGGSTITQQLAKNAFLTQEQTVTR 234
Cdd:PRK09506 205 SPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISlysIGRAVLANLTAGRtVQGGSTLTQQLVKNLFLSNERSLWR 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 235 KAKEFFLSLELTKKYSKQEILTMYLNNAYFG----NGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNI 310
Cdd:PRK09506 285 KANEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNP 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 311 RNATNRRNTVLanmvddKKLSQADADSAAGVDMAS-RLDDTYQGTGDDYKYPSYFDAVIEEATKTYGlsedEIVKN--GY 387
Cdd:PRK09506 365 KLALERRNLVL------RLLQQQQIIDQELYDMLSaRPLGVQPKGGVISPQPAFMQMVRQELQAKLG----DKVKDlsGV 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 388 KIYTEMDANSQANMQQTYENTNLFPTSESDGSTAQSASVALDPTTGAVRGLVgrvgGTSDTTFRNFNYATQGKRSPGSTI 467
Cdd:PRK09506 435 KIFTTLDPVSQDAAEKAVEEGIPALKKQRKLSDLETAMVVVDRFSGEVRAMV----GGSEPQFAGYNRAMQARRSIGSLA 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 468 KPlVVYAPALA--SGWSINKDLPNTPIDY---NG--YTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYG 540
Cdd:PRK09506 511 KP-ATYLTALSqpDKYRLNTWIADAPISLrqpNGqvWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTW 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 541 QKFGLNFDNVPEELGISLgGGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTS 620
Cdd:PRK09506 590 IKLGVPKDQLNPVPAMLL-GALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLY 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 621 MMLGTFSNGSA--VNANYTGYTMAGKTGTVQaefnkDLTsDQWVIGYTPDVVMTTWIGFDKTDESHyLTGASSgtASTIF 698
Cdd:PRK09506 669 TMQQVVQRGTGrqLGAKYPNLHLAGKTGTTN-----DLV-DSWFAGIDGKEVTITWVGRDNNQPTK-LYGASG--AMTIY 739
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
159-678 |
6.03e-62 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 222.41 E-value: 6.03e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 159 SLSGQKGTYVELDAISDSLENAVIATEDRTFYENSGVNV----KRFLLAIVSMGRFGGGSTITQQLAKNAFLTQEQTVTR 234
Cdd:PRK14850 151 SPEGKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLssigRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWR 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 235 KAKEFFLSLELTKKYSKQEILTMYLNNAYFG-NG---VWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNI 310
Cdd:PRK14850 231 KINEIYMALILDRFYSKDRILELYLNEVYLGqDGneqIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNP 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 311 RNATNRRNTVLANMVDDKKLSQADADsaagvDMASRLDDTYQGTGDDYKYPSYFDAVIEEATKTYGLSEDEIvkNGYKIY 390
Cdd:PRK14850 311 NLTLKRRNLVLFLLYKQKVITRKLYK-----DLCSRPLNVQSKGNIISSHPAFIQLVCEEFHKKIHYPFKNF--SGTKIF 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 391 TEMDANSQANMQQTYENTNLFPTSESDGSTAQSASVALDPTTGAVRGLVgrvgGTSDTTFRNFNYATQGKRSPGSTIKPl 470
Cdd:PRK14850 384 TTLDYISQNAAEQAVKIGIPILKRKKRLKDLEVAMVIIDRFSGEVRALI----GSSKPEFNGYNRALKARRSIGSLSKP- 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 471 VVYAPALA--SGWSINKDLPNTPIDY---NG--YTPTNYGGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKF 543
Cdd:PRK14850 459 ITYLTALSqpEKYHLNTWISDTPISIkldNGqyWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILL 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 544 GLNFDNVPEELGISLgGGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMML 623
Cdd:PRK14850 539 GISSNYITPLPSISL-GAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQ 617
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1937373635 624 GTFSNGSAVNAN--YTGYTMAGKTGTVQaefnkDLTsDQWVIGYTPDVVMTTWIGFD 678
Cdd:PRK14850 618 QVVKSGTAKSLGtiFKEFSLAGKTGTTN-----NLV-DSWFVGIDGKQVVITWIGRD 668
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
376-667 |
8.52e-42 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 161.15 E-value: 8.52e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 376 GLSEDEIVKNGYKIYTEMDANSQANMQQTYENTnlfptseSDGSTAQSAS-VALDPTTGAVRGLVGR--------VGGTS 446
Cdd:COG0768 208 DLGEEKPPVPGKDLVLTIDSDLQKIAEEALKKA-------VEEYKAKSGAvVVMDPKTGEILAMASYpsfdpnlfVGGPD 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 447 DTTFrnfNYATQGKRSPGSTIKPLVVYApALASGwSINkdlPNTPIDYNGY------TPTNYGGVETEDVPMYQALANSY 520
Cdd:COG0768 281 EPLR---NRAVQGTYEPGSTFKPFTAAA-ALEEG-VIT---PDTTFDCPGYyrvggrTIRDWDRGGHGTLTLTEALAKSS 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 521 NIPAVYLFNQIGIQKGISYGQKFGLNfdnvpEELGISLGG------------------------GVTASPLQMAQAYATF 576
Cdd:COG0768 353 NVGFYKLALRLGIDKLYDYLKKFGLG-----QKTGIDLPGeasgllpspkrwypgetatmsigqGLSVTPLQLAQAYAAI 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 577 ANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLGTFSN--GSAVNANYTGYTMAGKTGTVQAEFNK 654
Cdd:COG0768 428 ANGGVLVKPHLVKEIVDPDGEVVKEEPEVLRRVISPETAETVREGMEGVVNEpgGTARRAAIPGYRVAGKTGTAQVVDIG 507
|
330
....*....|....*...
gi 1937373635 655 DLTSDQ-----WVIGYTP 667
Cdd:COG0768 508 NGGYYKgrhiaSFVGFAP 525
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
167-323 |
2.23e-37 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 139.52 E-value: 2.23e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 167 YVELDAISDSLENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFG----GGSTITQQLAKNAFLTQEQTVTRKAKEFFLS 242
Cdd:TIGR02070 57 WRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGkvvrGGSTISQQLAKNLFLWSGRSYLRKGLEAWAT 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 243 LELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYnpiDNIRNA--TNRRNTV 320
Cdd:TIGR02070 137 WMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYY---DENRPGpyVRRKATW 213
|
...
gi 1937373635 321 LAN 323
Cdd:TIGR02070 214 ILK 216
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
110-324 |
7.60e-35 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 132.62 E-value: 7.60e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 110 KILFILVAMLVLTVGsYLFYIAKTTNVSDLQDAlkattviydkegnqagslsGQKGTYVELDAISDSLENAVIATEDRTF 189
Cdd:PRK13481 10 KILLTILIIIALFIG-IMYFLSTRDNVDELRKI-------------------ENKSSFVSADNMPEYVKGAFISMEDERF 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 190 YENSGVNVK---RFLLAIVSMGRFGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFGN 266
Cdd:PRK13481 70 YKHHGFDLKgttRALFSTISDRDVQGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQYSKNEILSFYLNNIYFGD 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1937373635 267 GVWGVEDASQKYFGTSA-------ANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLANM 324
Cdd:PRK13481 150 NQYTLEGAANHYFGTTVnknsttmSHITVLQSAILASKVNAPSVYNINDMSENFTQRVSTNLEKM 214
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
426-668 |
2.68e-33 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 130.23 E-value: 2.68e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 426 VALDPTTGAVRGLVGRVGGTSDTTFRNF-NYATQGKRSPGSTIKPLVVyAPALASG-WSINKDLPNTPIDYNGYTP-TNY 502
Cdd:pfam00905 4 VVLDPKTGEVLAMVGKPSYDPNGFIGPLrNRAVTSRYEPGSTFKPFTA-LAALDNGvLKPDETIFDWPGKQQGGKSiGDW 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 503 GGVETEDVPMYQALANSYNIPAVYLFNQIGIQKGISYGQKFGL-NFDNV--PEELG------------ISLGGGVTASPL 567
Cdd:pfam00905 83 NQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgNKTGIglPGENAgyltpywlegatASFGIGLTITPL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 568 QMAQAYATFANGGEMNTAYFITKIENasgdiIATHSKKSKRVISQSVANQMTSMMLGTFSNGSAVNANYT-GYTMAGKTG 646
Cdd:pfam00905 163 QQAQAYAAIANGGKLVPPHLVKSIED-----KVDPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTGTAAVpGYKVAGKTG 237
|
250 260
....*....|....*....|....*..
gi 1937373635 647 T-----VQAEFNKDLTSDQWVIGYTPD 668
Cdd:pfam00905 238 TaqvagPKGGGYYDGAQIGWFVGYAPA 264
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
168-580 |
5.97e-31 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 129.82 E-value: 5.97e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 168 VELDAISDSLENAVIATEDRTFYENSGVN---VKRFLLAIVSMGR-FGGGSTITQQLAKnAFLTQEQTVTRKAKEFFLSL 243
Cdd:PRK11240 65 VTIEDVSPRYLEALINYEDRWFWKHPGVNpfsVARAAWQDLTSGRvISGGSTLTMQVAR-LLDPHPRTFGGKIRQLWRAL 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 244 ELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIRNATNRRNTVLAN 323
Cdd:PRK11240 144 QLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLER 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 324 MVDDKKLSQADADSAA--GVDMASRlddtyqgtgddyKYPSYFDAVIEEATKTyglSEDEivkngyKIYTEMDANSQANM 401
Cdd:PRK11240 224 MAEQGVWSAEQVKESReePVWLAPR------------QMPQLAPLFARMMLGK---SKSD------KIVTTLDAGLQRRL 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 402 QQTYENTNlfptsesdGSTAQSASVAL---DPTTGAVRGLVGRVGGTSDTTFRNFNYATqGKRSPGSTIKPLvVYAPALA 478
Cdd:PRK11240 283 EDLALNWK--------GRLPPRSSLAMivvDHTDMAVRGWVGSVDLNDDSRFGHVDMVN-AIRSPGSVLKPF-VYGLALD 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 479 SGW----SINKDLPNTpidYNGYTPTNYGGVETEDVPMYQALANSYNIPAVYLFNqigiqkgiSYGQK-FGLNFDNVPEE 553
Cdd:PRK11240 353 DGLihpaSLLQDVPRR---TGDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLE--------AYGPKrFAAKLRNVGLP 421
|
410 420 430
....*....|....*....|....*....|....*.
gi 1937373635 554 LGISLG---------GGVTASPLQMAQAYATFANGG 580
Cdd:PRK11240 422 LYLPAGaepnlslilGGAGARLEDMVAAYSAFARHG 457
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
424-667 |
5.22e-25 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 110.31 E-value: 5.22e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 424 ASVALDPTTGAVRGLVGR--------VGGTSDTTFRN---------FNYATQGKRSPGSTIKPlVVYAPALASGwSINkd 486
Cdd:TIGR03423 250 AVVVMDPRTGEILAMVSTpsfdpnlfVDGISSKDYKAllndpdrplLNRAIQGVYPPGSTFKP-VVALAALEEG-VIT-- 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 487 lPNTPIDYNGYTptNYGGVETED--------VPMYQALANSYNipaVYlFNQIGIQKGI----SYGQKFGL----NFDnV 550
Cdd:TIGR03423 326 -PETRIYCPGYF--QLGGRRFRCwkrgghgrVDLRKAIEESCD---VY-FYQLALRLGIdkiaEYAKRFGFgqktGID-L 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 551 PEELG----------------------ISLG---GGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATH--S 603
Cdd:TIGR03423 398 PGEKSglvpsrewkrkrfgqpwypgdtLNVSigqGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTepE 477
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1937373635 604 KKSKRVISQSVANQMTSMMLG--TFSNGSAVNA-NYTGYTMAGKTGTVQ------------AEFNKDLTSDQWVIGYTP 667
Cdd:TIGR03423 478 VLRPLPISPENLDVVREGMRDvvNGPGGTARRArLGLPYKMAGKTGTAQvvslkqgekydaEQIPERLRDHALFVAFAP 556
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
393-649 |
2.86e-06 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 50.59 E-value: 2.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 393 MDANSQANMQQTYENTNLFPTSESdgstaqSASVALDPTTGAVRGLVG-------RVGGTSDTTFRNfnYATQGKRSPGS 465
Cdd:PRK15105 235 IDERLQALVYRELNNAVAFNKAES------GSAVLVDVNTGEVLAMANspsynpnNLSGTPKDAMRN--RAITDVFEPGS 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 466 TIKPLVVYApALASGWSINKDLPNTpidyngyTPTNYGGVETEDVPMYQALA------NSYNIPAVYLFNQIGIQKGISY 539
Cdd:PRK15105 307 TVKPMVVMT-ALQRGVVKENSVLNT-------VPYRINGHEIKDVARYSELTltgvlqKSSNVGVSKLALAMPSSALVDT 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 540 GQKFGL----NFDNVPEELGI---------------SLGGGVTASPLQMAQAYATFANGGeMNTAYFITKIENASGdiia 600
Cdd:PRK15105 379 YSRFGLgkatNLGLVGERSGLypqkqrwsdieratfSFGYGLMVTPLQLARVYATIGSYG-IYRPLSITKVDPPVP---- 453
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1937373635 601 thskkSKRVISQSVANQMTSMMLG-TFSNGSAVNANYTGYTMAGKTGTVQ 649
Cdd:PRK15105 454 -----GERVFPESIVRTVVHMMESvALPGGGGVKAAIKGYRIAIKTGTAK 498
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
386-649 |
1.45e-05 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 48.61 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 386 GYKIYTEMDANsqanmQQTYENTNLfptsesdgSTAQSASVALDPTTGAVRGLVGR--------VGGTSDTTFRNF---- 453
Cdd:PRK10795 248 GHDIYLTLDLK-----LQQYIETLL--------AGSRAAVVVTDPRTGGILALVSTpsydpnlfVDGISSKDYSGLlndp 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 454 -----NYATQGKRSPGSTIKPLVVYApALASGwSINKD----------LPNTPIDYNGYTPTNYGGVEtedvpMYQALAN 518
Cdd:PRK10795 315 nrpliNRATQGVYPPASTVKPYVAVS-ALSAG-VITRNtslfdpgwwqLPGSEKRYRDWKKWGHGRLN-----VTKSLEE 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 519 SynipAVYLFNQIGIQKGIS----------YGQKFGLNFD-----NVP----------------EELGISLGGGV-TASP 566
Cdd:PRK10795 388 S----ADTFFYQVAYDMGIDrlsewmgkfgYGHYTGIDLAeersgNMPtrewkqkrfkkpwyqgDTIPVGIGQGYwTATP 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1937373635 567 LQMAQAYATFANGGEMNTAYFI-TKIENasGDIIATHSKKSKRV---------ISQS----VANQMTSMMLGTFSNgsav 632
Cdd:PRK10795 464 IQMSKALMTLINDGIVKVPHLLmSTAED--GKQVPWVQPHEPPVgdihsgyweIAKDgmygVANRPNGTAHKYFAS---- 537
|
330
....*....|....*..
gi 1937373635 633 nanyTGYTMAGKTGTVQ 649
Cdd:PRK10795 538 ----APYKIAAKSGTAQ 550
|
|
| |
