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Conserved domains on  [gi|1914498005|ref|WP_192395416|]
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3-phosphoshikimate 1-carboxyvinyltransferase [Methylomonas fluvii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14806 super family cl36426
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; ...
 1-436 0e+00

bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional


The actual alignment was detected with superfamily member PRK14806:

Pssm-ID: 237820 [Multi-domain]  Cd Length: 735  Bit Score: 785.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   1 MSQTITFQVQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPVNGEVTIHGV 80
Cdd:PRK14806  298 NANDVSYSVLPGGAVKGTIRVPGDKSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEGPHNGRVTIHGV 377

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  81 GKHGLKAPEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGKAgK 160
Cdd:PRK14806  378 GLHGLKAPPGPLYMGNSGTSMRLLSGLLAAQSFDSVLTGDASLSKRPMERVAKPLREMGAVIETGEEGRPPLSIRGGQ-R 456

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 161 LQGIHYDMPIASAQVKSCLLLAGMYAEGETSVTEPAPTRDHTERMLNGFGYPVTREGSTARITNIGKLTAARIDVPSDIS 240
Cdd:PRK14806  457 LKGIHYDLPMASAQVKSCLLLAGLYAEGETSVTEPAPTRDHTERMLRGFGYPVKVEGNTISVEGGGKLTATDIEVPADIS 536

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 241 SAAFFLVGASIAPDSDVTLRHVGINPTRTGIIDILRLMGANIEVLNEREVGGEPVADLRVRSAQLKGINIPEHLVPLAID 320
Cdd:PRK14806  537 SAAFFLVAASIAEGSELTLEHVGINPTRTGVIDILKLMGADITLENEREVGGEPVADIRVRGARLKGIDIPEDQVPLAID 616

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 321 EFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKgGGYIGSGEVESHGDHRIAMSFSI 400
Cdd:PRK14806  617 EFPVLFVAAACAEGRTVLTGAEELRVKESDRIQVMADGLKTLGIDCEPTPDGIIIE-GGIFGGGEVESHGDHRIAMSFSV 695

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1914498005 401 AGLRSSGPITINDCANVNTSFPEFRDLATKLGLALT 436
Cdd:PRK14806  696 ASLRASGPITIHDCANVATSFPNFLELANQVGIRIE 731
 
Name Accession Description Interval E-value
PRK14806 PRK14806
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; ...
 1-436 0e+00

bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional


Pssm-ID: 237820 [Multi-domain]  Cd Length: 735  Bit Score: 785.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   1 MSQTITFQVQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPVNGEVTIHGV 80
Cdd:PRK14806  298 NANDVSYSVLPGGAVKGTIRVPGDKSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEGPHNGRVTIHGV 377

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  81 GKHGLKAPEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGKAgK 160
Cdd:PRK14806  378 GLHGLKAPPGPLYMGNSGTSMRLLSGLLAAQSFDSVLTGDASLSKRPMERVAKPLREMGAVIETGEEGRPPLSIRGGQ-R 456

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 161 LQGIHYDMPIASAQVKSCLLLAGMYAEGETSVTEPAPTRDHTERMLNGFGYPVTREGSTARITNIGKLTAARIDVPSDIS 240
Cdd:PRK14806  457 LKGIHYDLPMASAQVKSCLLLAGLYAEGETSVTEPAPTRDHTERMLRGFGYPVKVEGNTISVEGGGKLTATDIEVPADIS 536

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 241 SAAFFLVGASIAPDSDVTLRHVGINPTRTGIIDILRLMGANIEVLNEREVGGEPVADLRVRSAQLKGINIPEHLVPLAID 320
Cdd:PRK14806  537 SAAFFLVAASIAEGSELTLEHVGINPTRTGVIDILKLMGADITLENEREVGGEPVADIRVRGARLKGIDIPEDQVPLAID 616

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 321 EFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKgGGYIGSGEVESHGDHRIAMSFSI 400
Cdd:PRK14806  617 EFPVLFVAAACAEGRTVLTGAEELRVKESDRIQVMADGLKTLGIDCEPTPDGIIIE-GGIFGGGEVESHGDHRIAMSFSV 695

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1914498005 401 AGLRSSGPITINDCANVNTSFPEFRDLATKLGLALT 436
Cdd:PRK14806  696 ASLRASGPITIHDCANVATSFPNFLELANQVGIRIE 731
AroA COG0128
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ...
 1-431 0e+00

5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439898  Cd Length: 421  Bit Score: 589.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   1 MSQTItfqVQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPVNGEVTIHGV 80
Cdd:COG0128     1 MSSLT---IAPPSPLKGTVRVPGSKSISHRALLLAALAEGESTIRNLLESDDTLATLEALRALGAEIEELDGGTLRVTGV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  81 GkHGLKAPEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGkaGK 160
Cdd:COG0128    78 G-GGLKEPDAVLDCGNSGTTMRLLTGLLALQPGEVVLTGDESLRKRPMGRLLDPLRQLGARIESRGGGYLPLTIRG--GP 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 161 LQGIHYDMP-IASAQVKSCLLLAGMYAEG--ETSVT---EPAPTRDHTERMLNGFGYPVTREG-STARITNIGKLTAARI 233
Cdd:COG0128   155 LKGGEYEIPgSASSQFKSALLLAGPLAEGglEITVTgelESKPYRDHTERMLRAFGVEVEVEGyRRFTVPGGQRYRPGDY 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 234 DVPSDISSAAFFLVGASIApDSDVTLRHVGINPT--RTGIIDILRLMGANIEVLNERevggepvadLRVRSAQLKGINIP 311
Cdd:COG0128   235 TVPGDISSAAFFLAAAAIT-GSEVTVEGVGLNSTqgDTGILDILKEMGADIEIENDG---------ITVRGSPLKGIDID 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 312 EHLVPlaiDEFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGYIGSGEVESHGD 391
Cdd:COG0128   305 LSDIP---DEAPTLAVLAAFAEGTTRIRGAAELRVKESDRIAAMATELRKLGADVEETEDGLIIEGGPKLKGAEVDSYGD 381

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1914498005 392 HRIAMSFSIAGLRSSGPITINDCANVNTSFPEFRDLATKL 431
Cdd:COG0128   382 HRIAMAFAVAGLRAEGPVTIDDAECVAKSFPDFFELLESL 421
EPSP_synthase cd01556
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase ...
 15-431 2.35e-180

EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.


Pssm-ID: 238797  Cd Length: 409  Bit Score: 509.02  E-value: 2.35e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  15 LRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPvNGEVTIHGVGKhGLKAPEKPLYL 94
Cdd:cd01556     1 LSGEITVPGSKSISHRALLLAALAEGESRIENLLDSDDTLATLEALRALGAKIEEE-GGTVEIVGGGG-LGLPPEAVLDC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  95 GNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGkaGKLQGIHYDMPIA-SA 173
Cdd:cd01556    79 GNSGTTMRLLTGLLALQGGDSVLTGDESLRKRPMGRLVDALRQLGAEIEGREGGGYPPLIGG--GGLKGGEVEIPGAvSS 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 174 QVKSCLLLAGMYAEGETSVT----EPAPTRDHTERMLNGFGYPVTREG-STARITNIGKLTAARIDVPSDISSAAFFLVG 248
Cdd:cd01556   157 QFKSALLLAAPLAEGPTTIIigelESKPYIDHTERMLRAFGAEVEVDGyRTITVKGGQKYKGPEYTVEGDASSAAFFLAA 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 249 ASIAPdSDVTLRHVGINPTRTGIIDILRLMGANIEVLNEREVGGEPvadlrvrSAQLKGINIPEHLVPlaiDEFPVLFVA 328
Cdd:cd01556   237 AAITG-SEIVIKNVGLNSGDTGIIDVLKEMGADIEIGNEDTVVVES-------GGKLKGIDIDGNDIP---DEAPTLAVL 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 329 AACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGG-GYIGSGEVESHGDHRIAMSFSIAGLRSSG 407
Cdd:cd01556   306 AAFAEGPTRIRNAAELRVKESDRIAAMATELRKLGADVEETEDGLIIEGGpLKGAGVEVYTYGDHRIAMSFAIAGLVAEG 385

                         410       420
                  ....*....|....*....|....
gi 1914498005 408 PITINDCANVNTSFPEFRDLATKL 431
Cdd:cd01556   386 GVTIEDPECVAKSFPNFFEDLESL 409
aroA TIGR01356
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ...
 17-432 3.51e-149

3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273574  Cd Length: 409  Bit Score: 430.16  E-value: 3.51e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  17 GEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEgPVNGEVTIHGVGkhgLKAPEKPLYLGN 96
Cdd:TIGR01356   1 GEIRAPGSKSITHRALILAALAEGETRVRNLLRSEDTLATLDALRALGAKIE-DGGEVAVIEGVG---GKEPQAELDLGN 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  97 SGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIV-TQENGTAPLHIKGkaGKLQGIHYDMPIASAQV 175
Cdd:TIGR01356  77 SGTTARLLTGVLALADGEVVLTGDESLRKRPMGRLVDALRQLGAEISsLEGGGSLPLTISG--PLPGGIVYISGSASSQY 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 176 KSCLLLAGMY--AEGETSVTEPAPTRDHTERMLN---GFGYPVTREGS-TARITNIGKLTAARIDVPSDISSAAFFLVGA 249
Cdd:TIGR01356 155 KSALLLAAPAlqAVGITIVGEPLKSRPYIEITLDllgSFGVEVERSDGrKIVVPGGQKYGPQGYDVPGDYSSAAFFLAAA 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 250 SIAPdSDVTLRHVGINPTRTG--IIDILRLMGANIEVLNErevggepvaDLRVRSA-QLKGINIpehLVPLAIDEFPVLF 326
Cdd:TIGR01356 235 AITG-GRVTLENLGINPTQGDkaIIIVLEEMGADIEVEED---------DLIVEGAsGLKGIKI---DMDDMIDELPTLA 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 327 VAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGYIGSGEVESHGDHRIAMSFSIAGLRSS 406
Cdd:TIGR01356 302 VLAAFAEGVTRITGAEELRVKESDRIAAIAEELRKLGVDVEEFEDGLYIRGKKELKGAVVDTFGDHRIAMAFAVAGLVAE 381

                         410       420
                  ....*....|....*....|....*.
gi 1914498005 407 GPITINDCANVNTSFPEFRDLATKLG 432
Cdd:TIGR01356 382 GEVLIDDPECVAKSFPSFFDVLERLG 407
EPSP_synthase pfam00275
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
10-426 1.55e-138

EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);


Pssm-ID: 395213  Cd Length: 415  Bit Score: 403.22  E-value: 1.55e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  10 QPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEI--EGPVNGEVTIHGVGKHGLKA 87
Cdd:pfam00275   1 TGGSRLSGEVKIPGSKSNSHRALILAALAAGESTITNLLDSDDTLTMLEALRALGAEIikLDDEKSVVIVEGLGGSFEAP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  88 PEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQEN-GTAPLHIKGkaGKLQGIHY 166
Cdd:pfam00275  81 EDLVLDMGNSGTALRPLTGRLALQSGEVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGyNYAPLKVRG--LRLGGIHI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 167 DMPIASAQVKSCLLLAGMYAEGETSVTEPA--PTRDHTERMLNGFGYPVTREGSTARITNIG--KLTAARIDVPSDISSA 242
Cdd:pfam00275 159 DGDVSSQFVTSLLMLAALLAEGTTTIENLAsePYIDDTENMLKKFGAKIEGSGTELSITVKGgeKLPGQEYRVEGDRSSA 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 243 AFFLVGASIAPdSDVTLRHVGINPTRTG--IIDILRLMGANIEVlnerevggEPVADLRVRSAQLKGINIpehLVPLAID 320
Cdd:pfam00275 239 AYFLVAAAITG-GTVTVENVGINSLQGDeaLLEILEKMGAEITQ--------EEDADIVVGPPGLRGKAV---DIRTAPD 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 321 EFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGG-YIGSGEVESHGDHRIAMSFS 399
Cdd:pfam00275 307 PAPTTAVLAAFAEGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkELKGAEVDSYGDHRIAMALA 386

                         410       420
                  ....*....|....*....|....*..
gi 1914498005 400 IAGLRSSGPITINDCANVNTSFPEFRD 426
Cdd:pfam00275 387 LAGLVAEGETIIDDIECTDRSFPDFEE 413
 
Name Accession Description Interval E-value
PRK14806 PRK14806
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; ...
 1-436 0e+00

bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional


Pssm-ID: 237820 [Multi-domain]  Cd Length: 735  Bit Score: 785.34  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   1 MSQTITFQVQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPVNGEVTIHGV 80
Cdd:PRK14806  298 NANDVSYSVLPGGAVKGTIRVPGDKSISHRSIMLGSLAEGVTEVEGFLEGEDALATLQAFRDMGVVIEGPHNGRVTIHGV 377

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  81 GKHGLKAPEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGKAgK 160
Cdd:PRK14806  378 GLHGLKAPPGPLYMGNSGTSMRLLSGLLAAQSFDSVLTGDASLSKRPMERVAKPLREMGAVIETGEEGRPPLSIRGGQ-R 456

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 161 LQGIHYDMPIASAQVKSCLLLAGMYAEGETSVTEPAPTRDHTERMLNGFGYPVTREGSTARITNIGKLTAARIDVPSDIS 240
Cdd:PRK14806  457 LKGIHYDLPMASAQVKSCLLLAGLYAEGETSVTEPAPTRDHTERMLRGFGYPVKVEGNTISVEGGGKLTATDIEVPADIS 536

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 241 SAAFFLVGASIAPDSDVTLRHVGINPTRTGIIDILRLMGANIEVLNEREVGGEPVADLRVRSAQLKGINIPEHLVPLAID 320
Cdd:PRK14806  537 SAAFFLVAASIAEGSELTLEHVGINPTRTGVIDILKLMGADITLENEREVGGEPVADIRVRGARLKGIDIPEDQVPLAID 616

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 321 EFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKgGGYIGSGEVESHGDHRIAMSFSI 400
Cdd:PRK14806  617 EFPVLFVAAACAEGRTVLTGAEELRVKESDRIQVMADGLKTLGIDCEPTPDGIIIE-GGIFGGGEVESHGDHRIAMSFSV 695

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1914498005 401 AGLRSSGPITINDCANVNTSFPEFRDLATKLGLALT 436
Cdd:PRK14806  696 ASLRASGPITIHDCANVATSFPNFLELANQVGIRIE 731
AroA COG0128
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ...
 1-431 0e+00

5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439898  Cd Length: 421  Bit Score: 589.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   1 MSQTItfqVQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPVNGEVTIHGV 80
Cdd:COG0128     1 MSSLT---IAPPSPLKGTVRVPGSKSISHRALLLAALAEGESTIRNLLESDDTLATLEALRALGAEIEELDGGTLRVTGV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  81 GkHGLKAPEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGkaGK 160
Cdd:COG0128    78 G-GGLKEPDAVLDCGNSGTTMRLLTGLLALQPGEVVLTGDESLRKRPMGRLLDPLRQLGARIESRGGGYLPLTIRG--GP 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 161 LQGIHYDMP-IASAQVKSCLLLAGMYAEG--ETSVT---EPAPTRDHTERMLNGFGYPVTREG-STARITNIGKLTAARI 233
Cdd:COG0128   155 LKGGEYEIPgSASSQFKSALLLAGPLAEGglEITVTgelESKPYRDHTERMLRAFGVEVEVEGyRRFTVPGGQRYRPGDY 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 234 DVPSDISSAAFFLVGASIApDSDVTLRHVGINPT--RTGIIDILRLMGANIEVLNERevggepvadLRVRSAQLKGINIP 311
Cdd:COG0128   235 TVPGDISSAAFFLAAAAIT-GSEVTVEGVGLNSTqgDTGILDILKEMGADIEIENDG---------ITVRGSPLKGIDID 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 312 EHLVPlaiDEFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGYIGSGEVESHGD 391
Cdd:COG0128   305 LSDIP---DEAPTLAVLAAFAEGTTRIRGAAELRVKESDRIAAMATELRKLGADVEETEDGLIIEGGPKLKGAEVDSYGD 381

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1914498005 392 HRIAMSFSIAGLRSSGPITINDCANVNTSFPEFRDLATKL 431
Cdd:COG0128   382 HRIAMAFAVAGLRAEGPVTIDDAECVAKSFPDFFELLESL 421
PRK02427 PRK02427
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
 3-432 0e+00

3-phosphoshikimate 1-carboxyvinyltransferase; Provisional


Pssm-ID: 235037 [Multi-domain]  Cd Length: 435  Bit Score: 577.86  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   3 QTITFQVQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEgpvNGEVTIHGVGK 82
Cdd:PRK02427    1 MMMMLLIIPPSPLSGTVRVPGSKSISHRALLLAALAEGETTITNLLRSEDTLATLNALRALGVEIE---DDEVVVEGVGG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  83 HGLKAPEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGKaGKLQ 162
Cdd:PRK02427   78 GGLKEPEDVLDCGNSGTTMRLLTGLLALQPGEVVLTGDESLRKRPMGRLLDPLRQMGAKIEGRDEGYLPLTIRGG-KKGG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 163 GIHYDMPIASAQVKSCLLLAGMYAEG--ETSVTEPAPTRDHTE---RMLNGFGYPVTREGSTA----RITNIGKLTAARI 233
Cdd:PRK02427  157 PIEYDGPVSSQFVKSLLLLAPLFAEGdtETTVIEPLPSRPHTEitlRMLRAFGVEVENVEGWGyrriVIKGGQRLRGQDI 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 234 DVPSDISSAAFFLVGASIAPDSDVTLRHVGINPTRTG--IIDILRLMGANIEVLNEREvGGEPVADLRVRSAQLKGINIP 311
Cdd:PRK02427  237 TVPGDPSSAAFFLAAAAITGGSEVTITNVGLNSTQGGkaIIDVLEKMGADIEIENERE-GGEPVGDIRVRSSELKGIDID 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 312 ehlVPLAIDEFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGyiGSGEVESHGD 391
Cdd:PRK02427  316 ---IPDIIDEAPTLAVLAAFAEGTTVIRNAEELRVKETDRIAAMATELRKLGAEVEETEDGLIITGGP--LAGVVDSYGD 390

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 1914498005 392 HRIAMSFSIAGLRSSGPITINDCANVNTSFPEFRDLATKLG 432
Cdd:PRK02427  391 HRIAMAFAIAGLAAEGPVTIDDPECVAKSFPDFFEDLASLG 431
EPSP_synthase cd01556
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase ...
 15-431 2.35e-180

EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.


Pssm-ID: 238797  Cd Length: 409  Bit Score: 509.02  E-value: 2.35e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  15 LRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPvNGEVTIHGVGKhGLKAPEKPLYL 94
Cdd:cd01556     1 LSGEITVPGSKSISHRALLLAALAEGESRIENLLDSDDTLATLEALRALGAKIEEE-GGTVEIVGGGG-LGLPPEAVLDC 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  95 GNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGkaGKLQGIHYDMPIA-SA 173
Cdd:cd01556    79 GNSGTTMRLLTGLLALQGGDSVLTGDESLRKRPMGRLVDALRQLGAEIEGREGGGYPPLIGG--GGLKGGEVEIPGAvSS 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 174 QVKSCLLLAGMYAEGETSVT----EPAPTRDHTERMLNGFGYPVTREG-STARITNIGKLTAARIDVPSDISSAAFFLVG 248
Cdd:cd01556   157 QFKSALLLAAPLAEGPTTIIigelESKPYIDHTERMLRAFGAEVEVDGyRTITVKGGQKYKGPEYTVEGDASSAAFFLAA 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 249 ASIAPdSDVTLRHVGINPTRTGIIDILRLMGANIEVLNEREVGGEPvadlrvrSAQLKGINIPEHLVPlaiDEFPVLFVA 328
Cdd:cd01556   237 AAITG-SEIVIKNVGLNSGDTGIIDVLKEMGADIEIGNEDTVVVES-------GGKLKGIDIDGNDIP---DEAPTLAVL 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 329 AACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGG-GYIGSGEVESHGDHRIAMSFSIAGLRSSG 407
Cdd:cd01556   306 AAFAEGPTRIRNAAELRVKESDRIAAMATELRKLGADVEETEDGLIIEGGpLKGAGVEVYTYGDHRIAMSFAIAGLVAEG 385

                         410       420
                  ....*....|....*....|....
gi 1914498005 408 PITINDCANVNTSFPEFRDLATKL 431
Cdd:cd01556   386 GVTIEDPECVAKSFPNFFEDLESL 409
aroA TIGR01356
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ...
 17-432 3.51e-149

3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]


Pssm-ID: 273574  Cd Length: 409  Bit Score: 430.16  E-value: 3.51e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  17 GEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEgPVNGEVTIHGVGkhgLKAPEKPLYLGN 96
Cdd:TIGR01356   1 GEIRAPGSKSITHRALILAALAEGETRVRNLLRSEDTLATLDALRALGAKIE-DGGEVAVIEGVG---GKEPQAELDLGN 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  97 SGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIV-TQENGTAPLHIKGkaGKLQGIHYDMPIASAQV 175
Cdd:TIGR01356  77 SGTTARLLTGVLALADGEVVLTGDESLRKRPMGRLVDALRQLGAEISsLEGGGSLPLTISG--PLPGGIVYISGSASSQY 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 176 KSCLLLAGMY--AEGETSVTEPAPTRDHTERMLN---GFGYPVTREGS-TARITNIGKLTAARIDVPSDISSAAFFLVGA 249
Cdd:TIGR01356 155 KSALLLAAPAlqAVGITIVGEPLKSRPYIEITLDllgSFGVEVERSDGrKIVVPGGQKYGPQGYDVPGDYSSAAFFLAAA 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 250 SIAPdSDVTLRHVGINPTRTG--IIDILRLMGANIEVLNErevggepvaDLRVRSA-QLKGINIpehLVPLAIDEFPVLF 326
Cdd:TIGR01356 235 AITG-GRVTLENLGINPTQGDkaIIIVLEEMGADIEVEED---------DLIVEGAsGLKGIKI---DMDDMIDELPTLA 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 327 VAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGYIGSGEVESHGDHRIAMSFSIAGLRSS 406
Cdd:TIGR01356 302 VLAAFAEGVTRITGAEELRVKESDRIAAIAEELRKLGVDVEEFEDGLYIRGKKELKGAVVDTFGDHRIAMAFAVAGLVAE 381

                         410       420
                  ....*....|....*....|....*.
gi 1914498005 407 GPITINDCANVNTSFPEFRDLATKLG 432
Cdd:TIGR01356 382 GEVLIDDPECVAKSFPSFFDVLERLG 407
EPSP_synthase pfam00275
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
10-426 1.55e-138

EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);


Pssm-ID: 395213  Cd Length: 415  Bit Score: 403.22  E-value: 1.55e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  10 QPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEI--EGPVNGEVTIHGVGKHGLKA 87
Cdd:pfam00275   1 TGGSRLSGEVKIPGSKSNSHRALILAALAAGESTITNLLDSDDTLTMLEALRALGAEIikLDDEKSVVIVEGLGGSFEAP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  88 PEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQEN-GTAPLHIKGkaGKLQGIHY 166
Cdd:pfam00275  81 EDLVLDMGNSGTALRPLTGRLALQSGEVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGyNYAPLKVRG--LRLGGIHI 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 167 DMPIASAQVKSCLLLAGMYAEGETSVTEPA--PTRDHTERMLNGFGYPVTREGSTARITNIG--KLTAARIDVPSDISSA 242
Cdd:pfam00275 159 DGDVSSQFVTSLLMLAALLAEGTTTIENLAsePYIDDTENMLKKFGAKIEGSGTELSITVKGgeKLPGQEYRVEGDRSSA 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 243 AFFLVGASIAPdSDVTLRHVGINPTRTG--IIDILRLMGANIEVlnerevggEPVADLRVRSAQLKGINIpehLVPLAID 320
Cdd:pfam00275 239 AYFLVAAAITG-GTVTVENVGINSLQGDeaLLEILEKMGAEITQ--------EEDADIVVGPPGLRGKAV---DIRTAPD 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 321 EFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGG-YIGSGEVESHGDHRIAMSFS 399
Cdd:pfam00275 307 PAPTTAVLAAFAEGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkELKGAEVDSYGDHRIAMALA 386

                         410       420
                  ....*....|....*....|....*..
gi 1914498005 400 IAGLRSSGPITINDCANVNTSFPEFRD 426
Cdd:pfam00275 387 LAGLVAEGETIIDDIECTDRSFPDFEE 413
EPT-like cd01554
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine ...
 15-426 2.54e-107

Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.


Pssm-ID: 238795  Cd Length: 408  Bit Score: 323.40  E-value: 2.54e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  15 LRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPvNGEVTIHGVGKHGLKAPEKPLYL 94
Cdd:cd01554     1 LHGIIRVPGDKSISHRSLIFASLAEGETKVYNILRGEDVLSTMQVLRDLGVEIEDK-DGVITIQGVGMAGLKAPQNALNL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  95 GNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQENGTAPLHIKGkAGKLQGIHYDMPIASAQ 174
Cdd:cd01554    80 GNSGTAIRLISGVLAGADFEVELFGDDSLSKRPMDRVTLPLKKMGASISGQEERDLPPLLKG-GKNLGPIHYEDPIASAQ 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 175 VKSCLLLAGMYAEGETSVTEPA--PTRDHTERMLNGFGYPVTREGsTARITNIG--KLTAARIDVPSDISSAAFFLVGAS 250
Cdd:cd01554   159 VKSALMFAALLAKGETVIIEAAkePTINHTENMLQTFGGHISVQG-TKKIVVQGpqKLTGQKYVVPGDISSAAFFLVAAA 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 251 IAPdSDVTLRHVGINPTRTGIIDILRLMGANIEVlnerevgGEpvADLRVRSAQLKGINIPEHLVPLAIDEFPVLFVAAA 330
Cdd:cd01554   238 IAP-GRLVLQNVGINETRTGIIDVLRAMGAKIEI-------GE--DTISVESSDLKATEICGALIPRLIDELPIIALLAL 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 331 CADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGYIGSGEVESHGDHRIAMSFSIAGLRSSGPIT 410
Cdd:cd01554   308 QAQGTTVIKDAEELKVKETDRIFVVADELNSMGADIEPTADGMIIKGKEKLHGARVNTFGDHRIGMMTALAALVADGEVE 387

                         410
                  ....*....|....*.
gi 1914498005 411 INDCANVNTSFPEFRD 426
Cdd:cd01554   388 LDRAEAINTSYPSFFD 403
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
1-429 5.68e-49

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 176.78  E-value: 5.68e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   1 MSQTITFQVQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEgPVNGEVTIHGV 80
Cdd:PRK11860    1 MFSTEFLDLPPLLSAGGTVRLPGSKSISNRVLLLAALSEGTTTVRDLLDSDDTRVMLDALRALGCGVE-QLGDTYRITGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  81 GKHgLKAPEKPLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEI-VTQENGTAPLHIKGKAG 159
Cdd:PRK11860   80 GGQ-FPVKQADLFLGNAGTAMRPLTAALALLGGEYELSGVPRMHERPIGDLVDALRQLGCDIdYLGNEGFPPLRIGPAPL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 160 KLQGihydmPIA-----SAQVKSCLLLAGMYAEGETSVTE------PAPTRDHTERMLNGFGYPVTREG-------STAR 221
Cdd:PRK11860  159 RLDA-----PIRvrgdvSSQFLTALLMALPLVARRDITIEvvgeliSKPYIEITLNLLARFGIAVQREGwqrftipAGSR 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 222 ITNIGkltaaRIDVPSDISSAAFFLVGASIAPDSDVTLRHVGINPTRTGI--IDILRLMGANIEvlnerevGGEPVADLR 299
Cdd:PRK11860  234 YRSPG-----EIHVEGDASSASYFIAAGAIAGGAPVRIEGVGRDSIQGDIrfAEAARAMGAQVT-------SGPNWLEVR 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 300 VRSAQLKGINIPEHLVPlaiDEFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIK--- 376
Cdd:PRK11860  302 RGAWPLKAIDLDCNHIP---DAAMTLAVMALYADGTTTLRNIASWRVKETDRIAAMATELRKLGATVEEGADYIRVTppa 378

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1914498005 377 GGGYIGSGEVESHGDHRIAMSFSIAGLRSSG-PITINDCANVNTSFPE-FRDLAT 429
Cdd:PRK11860  379 QAADWKAAAIHTYDDHRMAMCFSLAAFNPAGlPVRINDPKCVAKTFPDyFEALFS 433
PLN02338 PLN02338
3-phosphoshikimate 1-carboxyvinyltransferase
 9-426 2.70e-44

3-phosphoshikimate 1-carboxyvinyltransferase


Pssm-ID: 177972 [Multi-domain]  Cd Length: 443  Bit Score: 160.30  E-value: 2.70e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   9 VQPGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIE-GPVNGEVTIHGV-GKHGLK 86
Cdd:PLN02338    6 LQPIKEISGTVKLPGSKSLSNRILLLAALSEGTTVVDNLLDSDDIRYMLGALKTLGLNVEeDSENNRAVVEGCgGKFPVS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  87 APEKP---LYLGNSGTSMRLLSGLL--AGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEI-VTQENGTAPLHIKGKAGK 160
Cdd:PLN02338   86 GDSKEdveLFLGNAGTAMRPLTAAVtaAGGNASYVLDGVPRMRERPIGDLVDGLKQLGADVeCTLGTNCPPVRVNAAGGL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 161 LQGIHYDMPIASAQVKSCLLLAGMYAEG--ETSVTE---PAPTRDHTERMLNGFGYPVTREGSTARITNIGKLT---AAR 232
Cdd:PLN02338  166 PGGKVKLSGSISSQYLTALLMAAPLALGdvEIEIVDkliSVPYVEMTLKLMERFGVSVEHSDSWDRFFIKGGQKyksPGN 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 233 IDVPSDISSAAFFLVGASIAPDSdVTLRHVGINPTR--TGIIDILRLMGANIE-VLNEREVGGEPVADLRVRsaQLKGIN 309
Cdd:PLN02338  246 AYVEGDASSASYFLAGAAITGGT-VTVEGCGTTSLQgdVKFAEVLEKMGAKVEwTENSVTVTGPPRDAFGGK--HLKAID 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 310 IPEHLVPlaiDEFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGYIGSGEVESH 389
Cdd:PLN02338  323 VNMNKMP---DVAMTLAVVALFADGPTAIRDVASWRVKETERMIAICTELRKLGATVEEGPDYCIITPPKKLKPAEIDTY 399

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 1914498005 390 GDHRIAMSFSIAGLrSSGPITINDCANVNTSFPEFRD 426
Cdd:PLN02338  400 DDHRMAMAFSLAAC-GDVPVTINDPGCTRKTFPTYFD 435
PRK11861 PRK11861
bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
 11-426 7.91e-35

bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Provisional


Pssm-ID: 183343 [Multi-domain]  Cd Length: 673  Bit Score: 137.14  E-value: 7.91e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  11 PGGSLRGEIRVPGDKSMSHRSIMLGSLAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGpvNGEVTIHGVGKHGLKAPEK 90
Cdd:PRK11861  247 PFSHAQGTVRLPGSKSISNRVLLLAALAEGETTVTNLLDSDDTRVMLDALTKLGVKLSR--DGGTCVVGGTRGAFTAKTA 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  91 PLYLGNSGTSMRLLSGLLAGQPFDCVLTGDKSLESRPMKRVTVPLAQMGAEIVTQEN-GTAPLHIKGKAgklqgIHYDMP 169
Cdd:PRK11861  325 DLFLGNAGTAVRPLTAALAVNGGEYRIHGVPRMHERPIGDLVDGLRQIGARIDYEGNeGFPPLRIRPAT-----ISVDAP 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 170 I-----ASAQVKSCLL--LAGMYAEGETSVTE------PAPTRDHTERMLNGFGYPVTREGSTARITNIG--KLTAARID 234
Cdd:PRK11861  400 IrvrgdVSSQFLTALLmtLPLVKAKDGASVVEidgeliSKPYIEITIKLMARFGVTVERDGWQRFTVPAGvrYRSPGTIM 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 235 VPSDISSAAFFLVGASIAPDSdvtLRHVGINPTR----TGIIDILRLMGANIEVLNE----REVGGEpvadlrvrSAQLK 306
Cdd:PRK11861  480 VEGDASSASYFLAAGALGGGP---LRVEGVGRASiqgdVGFANALMQMGANVTMGDDwievRGIGHD--------HGRLA 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 307 GINIPEHLVPlaiDEFPVLFVAAACADGQTVLTGAEELRVKESDRIQVMADGLQILGVDAQPTKDGMVIKGGGYIG-SGE 385
Cdd:PRK11861  549 PIDMDFNLIP---DAAMTIAVAALFADGPSTLRNIGSWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAQLTpNAS 625

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 1914498005 386 VESHGDHRIAMSFSIAGLrSSGPITINDCANVNTSFPEFRD 426
Cdd:PRK11861  626 IDTYDDHRMAMCFSLVSL-GGVPVRINDPKCVGKTFPDYFD 665
MurA COG0766
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ...
 7-339 3.26e-11

UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440529  Cd Length: 416  Bit Score: 64.62  E-value: 3.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   7 FQVQPGGSLRGEIRVPGDKSmshrS---IMLGS-LAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPVNGEVTIHGVGK 82
Cdd:COG0766     4 LIIEGGKPLSGEVRISGAKN----AalpILAAAlLTDGPVTLRNVPDLSDVRTMLELLESLGVKVERDDGGTLTIDASNI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  83 HGLKAPEKplyLGNsgtSMR----LLSGLLAgqpfdcvltgdkslesRpMKRVTVP------------------LAQMGA 140
Cdd:COG0766    80 NSTEAPYE---LVR---KMRasilVLGPLLA----------------R-FGEARVSlpggcaigarpidlhlkgLEALGA 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 141 EIvTQENGtaplHIKGKAGKLQGIHYDMPIAS----AQvkscLLLAGMYAEGETSVT----EPaptrdhtE-----RMLN 207
Cdd:COG0766   137 EI-EIEHG----YIEARAGRLKGARIYLDFPSvgatEN----IMMAAVLAEGTTVIEnaarEP-------EivdlaNFLN 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 208 GFGYPVTREGS-TARITNIGKLTAARIDVPSDISSAAFFLVGASIApDSDVTLRHVGINPTRTgIIDILRLMGANIEVLN 286
Cdd:COG0766   201 AMGAKIEGAGTdTITIEGVEKLHGAEHTVIPDRIEAGTFLVAAAIT-GGDVTVKNVIPEHLEA-VLAKLREAGVEIEEGD 278

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1914498005 287 ErevggepvaDLRVRSAQ-LKGINIpehlvplAIDEFP--------VLFVAAACADGQTVLT 339
Cdd:COG0766   279 D---------GIRVRGPGrLKAVDI-------KTAPYPgfptdlqaQFMALLTQAEGTSVIT 324
PRK09369 PRK09369
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
 7-310 2.94e-09

UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated


Pssm-ID: 236486  Cd Length: 417  Bit Score: 58.50  E-value: 2.94e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005   7 FQVQPGGSLRGEIRVPGDKSmshrS---IMLGS-LAEGVTHVTGFLNAEDAISTLEAFRAMGVEIEGPVNGEVTIHGvgk 82
Cdd:PRK09369    4 LVIEGGKPLSGEVTISGAKN----AalpILAASlLAEEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDGNGTVTIDA--- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005  83 HGLKAPEKPLYLGNSgtsMR---LLSG-LLAgqpfdcvltgdkslesRpMKRVTVP------------------LAQMGA 140
Cdd:PRK09369   77 SNINNTEAPYELVKK---MRasiLVLGpLLA----------------R-FGEAKVSlpggcaigarpvdlhlkgLEALGA 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 141 EIvTQENGtaplHIKGKA-GKLQGIHYDMPIAS----AQvkscLLLAGMYAEGETSVT----EPaptrdhtE-----RML 206
Cdd:PRK09369  137 EI-EIEHG----YVEAKAdGRLKGAHIVLDFPSvgatEN----ILMAAVLAEGTTVIEnaarEP-------EivdlaNFL 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914498005 207 NGFGYPVTREGS-TARITNIGKLTAARIDVPSDISSAAFFLVGASIApDSDVTLRHVGINPTRTgIIDILRLMGANIEVL 285
Cdd:PRK09369  201 NKMGAKISGAGTdTITIEGVERLHGAEHTVIPDRIEAGTFLVAAAIT-GGDVTIRGARPEHLEA-VLAKLREAGAEIEEG 278

                         330       340
                  ....*....|....*....|....*.
gi 1914498005 286 NErevggepvaDLRVRSAQ-LKGINI 310
Cdd:PRK09369  279 ED---------GIRVDMPGrLKAVDI 295
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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