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Conserved domains on  [gi|1828715824|ref|WP_167595367|]
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Rib/alpha-like domain-containing protein [Lactobacillus jensenii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 975-1060 8.15e-15

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 71.10  E-value: 8.15e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  975 DNEKYTAIGKTQNLQKGQSANPQDFIANKDgevsqdgktytKLPDGTKYEWVDGgIDTSTIGPKQAQVKVTYPDGTTQIV 1054
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNKD-----------DLPEGTKYTWKTP-PDTTTPGDKTGTVVVTYPDGSTDEV 68


                   ....*.
gi 1828715824 1055 PVKANV 1060
Cdd:pfam08428   69 EVTVTV 74
Pectate_lyase_5 pfam20585
Putative pectate lyase-like adhesive domain; This putative domain is found at the N-terminus ...
 166-284 1.37e-14

Putative pectate lyase-like adhesive domain; This putative domain is found at the N-terminus of a large number of bacterial proteins. Its adhesive function was described in Lactobacillus reuteri serine-rich repeat proteins. Structure predictions show it is composed of a beta solenoid repeat related to Pectate lyase.


:

Pssm-ID: 466734  Cd Length: 126  Bit Score: 72.45  E-value: 1.37e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  166 TANVSDFDSFNSALMNQNITTININSDFTSGNYGTNVEHRRVVP---RTLVINGNGHTVDLGSIGY-FMNPGGNQAADW- 240
Cdd:pfam20585    1 TVEVSTWAEFKAALNDANVTTINLTADITVTSAGGGGYVYLTTSniaRSLTIDGNGHTLDFGARAInFYDINVKTANSWd 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1828715824  241 -TVENGTFYSKSAVGPFALTGDhgtdkawQATNGAVHRMTYKDMT 284
Cdd:pfam20585   81 iTLENLTITNGNYYGFFWSNDL-------NTDNQAGSTVTYKNVT 118
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 889-974 5.10e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 69.18  E-value: 5.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  889 DADKFTPEGGTIKVDNGHKLDgndAYEAIKNHDDLPADKAgYNWVVdenhpAVDTTKPGDQTGYVQVTYNDGSKsDLVPV 968
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD---AEDGIKNKDDLPEGTK-YTWKT-----PPDTTTPGDKTGTVVVTYPDGST-DEVEV 70


                   ....*.
gi 1828715824  969 TVHVIA 974
Cdd:pfam08428   71 TVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 2029-2107 5.30e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.79  E-value: 5.30e-14
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1828715824 2029 QSDGYDVEPQLVNTDKnGQLPNAKEGIKNLADLPEGTNPTWadraQDKINKTKPGtDTTAQVVVTFPDGSTKEVTVPVH 2107
Cdd:pfam08428    1 DADKYTPKGKDITVEV-GETPDAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTVT 73
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1486-1571 7.10e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.79  E-value: 7.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1486 ANDYKPEGTTIYAGLNEDITnrAADGIANKDQMPVAnkpegtvhTTYSWKDNiiPDTTKPGTKYGIVEVNFPDGSTKDVP 1565
Cdd:pfam08428    2 ADKYTPKGKDITVEVGETPD--AEDGIKNKDDLPEG--------TKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVE 69


                   ....*.
gi 1828715824 1566 VEVKVT 1571
Cdd:pfam08428   70 VTVTVT 75
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1409-1483 1.23e-13

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.02  E-value: 1.23e-13
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824 1409 DAEKYQLKAHDIWTYINDTPVAEKAVSNLDELKDVSSITWATTPDVSKVGNVPAIVVVTYKDGTSNAAPINIEVK 1483
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNKDDLPEGTKYTWKTPPDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1145-1230 7.67e-13

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 65.71  E-value: 7.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1145 DAEKYSPVPETISVPKGTDLSgrAKDGIANADKdangkekLPDGTKYEWDGGvPNTSVTNNKYGHVKVTYPDGSSTVVEV 1224
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD--AEDGIKNKDD-------LPEGTKYTWKTP-PDTTTPGDKTGTVVVTYPDGSTDEVEV 70


                   ....*.
gi 1828715824 1225 PLNITD 1230
Cdd:pfam08428   71 TVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1668-1757 2.29e-12

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 64.17  E-value: 2.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1668 DADRNTPETQTIKTLPGQTVNPEDGVinlhkpgENNPQLPDGTKVTFDNQSDVDDftkhgmPGsDKSFDATVTYPDGTTD 1747
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGI-------KNKDDLPEGTKYTWKTPPDTTT------PG-DKTGTVVVTYPDGSTD 66

                           90
                   ....*....|
gi 1828715824 1748 KIKLPVHITA 1757
Cdd:pfam08428   67 EVEVTVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1316-1402 1.06e-10

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 59.55  E-value: 1.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1316 DASKYGIETQEINVHEGTDISsdewARKGILNADQagkqneqLPDGTSYTWANGnvPDTTKPNKKTGYVTVTFPDNSSRT 1395
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD----AEDGIKNKDD-------LPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDE 67


                   ....*..
gi 1828715824 1396 VPVIVNV 1402
Cdd:pfam08428   68 VEVTVTV 74
rib_alpha super family cl46943
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1092-1151 1.62e-10

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


The actual alignment was detected with superfamily member TIGR02331:

Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 59.12  E-value: 1.62e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824 1092 KDKSTNLPTDP--SAYTWVNGA-PDTSKTGDIPATVKVTYPDGSYNTVDVTVHVT---SDAEKYSP 1151
Cdd:TIGR02331   13 SDSITNLVDLPdgTTYVWKTVNtPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTpprTDADKYDP 78
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1758-1851 1.62e-10

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 59.16  E-value: 1.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1758 DNEVNTPITQGIITPKDSVPDANKGIANLkkattkegktyPALPENTTVEWVNPGQMKTElenakggTTKNYDAVVIYPD 1837
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNK-----------DDLPEGTKYTWKTPPDTTTP-------GDKTGTVVVTYPD 62

                           90
                   ....*....|....
gi 1828715824 1838 KSTEIVSIPVTVAT 1851
Cdd:pfam08428   63 GSTDEVEVTVTVTD 76
aRib pfam18938
Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a ...
 2201-2269 4.43e-08

Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a variety of bacterial cell surface proteins. These proteins share a conserved motif with the Rib domain (YPDXXD). The structure of the aRib domain has been solved from two proteins, the SrpA adhesin and the GspB adhesin. In these proteins this domain has been termed the unique domain due to its lack of similarity to any other known structures at the time. The aRib domain from SrpA has been shown to mediate a dimer interaction. This family has been added to the E-set clan based on its similarity to the Rib domain, although it does not contain the Ig fold.


:

Pssm-ID: 465921 [Multi-domain]  Cd Length: 71  Bit Score: 51.84  E-value: 4.43e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 2201 TLNPPTdKVPVDDTKHITDEDKGKVIDNVKKSNPDK-DITDAHVDDDG--TFHGKvDGQDVVIPGTETVVEK 2269
Cdd:pfam18938    2 TINIPE-KTEVKDPNKLTDEEKQEVKDAVKKANPDLpEGTKVEVDDDGtvTVTYP-DGSKDTIPAKDLVKEK 71
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1235-1313 4.59e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 52.23  E-value: 4.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1235 DAEKHNPQANILHATLNQDLSsndwAKKGILNADE-QDGATFRWRKGyvPDTSKEGQVWGIVVVSYPDSSINEVRVPVIV 1313
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD----AEDGIKNKDDlPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVEVTVTV 74
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1946-2025 9.37e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 51.07  E-value: 9.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1946 QSDDYNIETQPVNTDKdGNLPeNADSGIKNLGKLPEGTHASWgdgaQDIAKNLKPGeTKDVPATVVFPDGSKKEITIPVH 2025
Cdd:pfam08428    1 DADKYTPKGKDITVEV-GETP-DAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTVT 73
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 2135-2191 1.19e-07

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 51.07  E-value: 1.19e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1828715824 2135 NADSGIKNLGDLPEGTHAVWgqgaQTIVDGMKPGeTKDVPATIEFPDGSTKDVTIPV 2191
Cdd:pfam08428   21 DAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTV 72
aRib pfam18938
Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a ...
 2273-2341 2.74e-07

Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a variety of bacterial cell surface proteins. These proteins share a conserved motif with the Rib domain (YPDXXD). The structure of the aRib domain has been solved from two proteins, the SrpA adhesin and the GspB adhesin. In these proteins this domain has been termed the unique domain due to its lack of similarity to any other known structures at the time. The aRib domain from SrpA has been shown to mediate a dimer interaction. This family has been added to the E-set clan based on its similarity to the Rib domain, although it does not contain the Ig fold.


:

Pssm-ID: 465921 [Multi-domain]  Cd Length: 71  Bit Score: 49.91  E-value: 2.74e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 2273 SLNPPTdKVPVDDTKHITDEDKGKVIDNVKKSNPDK-DITDAHVDDDG--TFHGKvDGQDVVIPGIETVVEK 2341
Cdd:pfam18938    2 TINIPE-KTEVKDPNKLTDEEKQEVKDAVKKANPDLpEGTKVEVDDDGtvTVTYP-DGSKDTIPAKDLVKEK 71
rib_alpha super family cl46943
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 823-897 6.42e-07

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


The actual alignment was detected with superfamily member TIGR02331:

Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 49.10  E-value: 6.42e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1828715824  823 DASQYITNKDEIanikPGTTDYEPTfksaAWKSVDTNT---KKGIITVTYADNTTTDLDVDLNVVDKITDADKFTPEG 897
Cdd:TIGR02331   11 DASDSITNLVDL----PDGTTYVWK----TVNTPDTNTpgdKPAVVVVTYPDGTKDTVPVTVHVTPPRTDADKYDPAG 80
COG4625 super family cl34793
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 118-634 2.17e-06

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


The actual alignment was detected with superfamily member COG4625:

Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 53.24  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  118 TQDRTDSNDNATTNQVDTTQVSTTSLKAVQSSNQAANLLAESKVEDSTTANVSDFDSFNSALMNQNITTININSDFTSGN 197
Cdd:COG4625     23 GGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGTGGVGGGGGGGGG 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  198 YGTNVEHRRVVPRTLVINGNGHTVDLGSIGYFMNPGGNQAADWTVENGTFYSKSAVGPFALTGDHGTDKAWQATNGAVHR 277
Cdd:COG4625    103 GGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGG 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  278 MTYKDMTVYAGGGAYAANAEIDLEGTNNLNATASYQSKFSNGTVYTETGGNRSGVEGQWIIIKDNANVTVNTDHGQAIST 357
Cdd:COG4625    183 GGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGG 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  358 EYSDGNHRIEVGENATLNGNYLYTTYGTPYGGGKIPVLSNGANGGTVIFHKGSKSHFTMPNQNVTGFGGNGFSNYGT--- 434
Cdd:COG4625    263 GAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGsgg 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  435 GSVLYLGAANTTIEKGAEVTIDNPKEANNDNSIFIRSDGTQLNIFGNLIINDGARDYTIRADNRVSINVGQSIADDDYSN 514
Cdd:COG4625    343 AGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGG 422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  515 DNGKLIINRNGDFYLNNDGGALSMWGPITINVNSGAALEVYSTGINNVSGSGANPALMRVGGSSKLNVYKRGTFILSDSS 594
Cdd:COG4625    423 GGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGS 502

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1828715824  595 NGKVSL----VDDYNANGNFNFDNTAKVIFDISNNNNQNSRIFA 634
Cdd:COG4625    503 TLAVEVdaanSDRLVVTGTATLNGGTVVVLAGGYAPGTTYTILA 546
Gram_pos_anchor pfam00746
LPXTG cell wall anchor motif;
2382-2419 1.12e-05

LPXTG cell wall anchor motif;


:

Pssm-ID: 366278 [Multi-domain]  Cd Length: 43  Bit Score: 44.45  E-value: 1.12e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1828715824 2382 KQNRLPQTGSE-TSGLSALGLAMLsLVGLGFLIKKRKED 2419
Cdd:pfam00746    5 KKKTLPKTGENsNIFLTAAGLLAL-LGGLLLLVKRRKKE 42
YSIRK_signal pfam04650
YSIRK type signal peptide; Many surface proteins found in Streptococcus, Staphylococcus, and ...
 17-42 2.20e-05

YSIRK type signal peptide; Many surface proteins found in Streptococcus, Staphylococcus, and related lineages share apparently homologous signal sequences. A motif resembling [YF]SIRKxxxGxxS[VIA] appears at the start of the transmembrane domain. The GxxS motif appears perfectly conserved, suggesting a specific function and not just homology. There is a strong correlation between proteins carrying this region at the N-terminus and those carrying the Gram-positive anchor domain with the LPXTG sortase processing site at the C-terminus.


:

Pssm-ID: 428049 [Multi-domain]  Cd Length: 26  Bit Score: 43.14  E-value: 2.20e-05
                           10        20
                   ....*....|....*....|....*.
gi 1828715824   17 KEQQHFALRKLNVGLVSVLMGTTLFF 42
Cdd:pfam04650    1 EKKQRYSIRKLSVGVASVLIGTLLFL 26
Rib super family cl48017
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1587-1667 2.28e-04

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


The actual alignment was detected with superfamily member pfam08428:

Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 41.83  E-value: 2.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1587 IAKYKGNIPQASDGIANKDqatkegdkdfpslaDVLAPNGIQWKKNfePDLSKPGLTSGEAILTFKDGSTAEVTIPVLVQ 1666
Cdd:pfam08428   12 ITVEVGETPDAEDGIKNKD--------------DLPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75


                   .
gi 1828715824 1667 T 1667
Cdd:pfam08428   76 D 76
Big_6 super family cl39386
Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial ...
 726-803 5.10e-04

Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.


The actual alignment was detected with superfamily member pfam17936:

Pssm-ID: 465576 [Multi-domain]  Cd Length: 83  Bit Score: 41.07  E-value: 5.10e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1828715824  726 FTDNGAQIKGSvvdesTNTGAVAVAYDKDNNKVGSGNVDDQGNFTINLDKPLLNKEEVKVrieTPRGASGFVSTTAPL 803
Cdd:pfam17936   10 VSDDGTTLTGT-----GEAGATVTVKDADGNVLGTGTVDADGTFSVTLDPAQANGETLSV---TATDAAGNVSPAATI 79
 
Name Accession Description Interval E-value
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 975-1060 8.15e-15

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 71.10  E-value: 8.15e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  975 DNEKYTAIGKTQNLQKGQSANPQDFIANKDgevsqdgktytKLPDGTKYEWVDGgIDTSTIGPKQAQVKVTYPDGTTQIV 1054
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNKD-----------DLPEGTKYTWKTP-PDTTTPGDKTGTVVVTYPDGSTDEV 68


                   ....*.
gi 1828715824 1055 PVKANV 1060
Cdd:pfam08428   69 EVTVTV 74
Pectate_lyase_5 pfam20585
Putative pectate lyase-like adhesive domain; This putative domain is found at the N-terminus ...
 166-284 1.37e-14

Putative pectate lyase-like adhesive domain; This putative domain is found at the N-terminus of a large number of bacterial proteins. Its adhesive function was described in Lactobacillus reuteri serine-rich repeat proteins. Structure predictions show it is composed of a beta solenoid repeat related to Pectate lyase.


Pssm-ID: 466734  Cd Length: 126  Bit Score: 72.45  E-value: 1.37e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  166 TANVSDFDSFNSALMNQNITTININSDFTSGNYGTNVEHRRVVP---RTLVINGNGHTVDLGSIGY-FMNPGGNQAADW- 240
Cdd:pfam20585    1 TVEVSTWAEFKAALNDANVTTINLTADITVTSAGGGGYVYLTTSniaRSLTIDGNGHTLDFGARAInFYDINVKTANSWd 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1828715824  241 -TVENGTFYSKSAVGPFALTGDhgtdkawQATNGAVHRMTYKDMT 284
Cdd:pfam20585   81 iTLENLTITNGNYYGFFWSNDL-------NTDNQAGSTVTYKNVT 118
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 889-974 5.10e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 69.18  E-value: 5.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  889 DADKFTPEGGTIKVDNGHKLDgndAYEAIKNHDDLPADKAgYNWVVdenhpAVDTTKPGDQTGYVQVTYNDGSKsDLVPV 968
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD---AEDGIKNKDDLPEGTK-YTWKT-----PPDTTTPGDKTGTVVVTYPDGST-DEVEV 70


                   ....*.
gi 1828715824  969 TVHVIA 974
Cdd:pfam08428   71 TVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 2029-2107 5.30e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.79  E-value: 5.30e-14
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1828715824 2029 QSDGYDVEPQLVNTDKnGQLPNAKEGIKNLADLPEGTNPTWadraQDKINKTKPGtDTTAQVVVTFPDGSTKEVTVPVH 2107
Cdd:pfam08428    1 DADKYTPKGKDITVEV-GETPDAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTVT 73
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1486-1571 7.10e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.79  E-value: 7.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1486 ANDYKPEGTTIYAGLNEDITnrAADGIANKDQMPVAnkpegtvhTTYSWKDNiiPDTTKPGTKYGIVEVNFPDGSTKDVP 1565
Cdd:pfam08428    2 ADKYTPKGKDITVEVGETPD--AEDGIKNKDDLPEG--------TKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVE 69


                   ....*.
gi 1828715824 1566 VEVKVT 1571
Cdd:pfam08428   70 VTVTVT 75
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1409-1483 1.23e-13

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.02  E-value: 1.23e-13
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824 1409 DAEKYQLKAHDIWTYINDTPVAEKAVSNLDELKDVSSITWATTPDVSKVGNVPAIVVVTYKDGTSNAAPINIEVK 1483
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNKDDLPEGTKYTWKTPPDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1145-1230 7.67e-13

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 65.71  E-value: 7.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1145 DAEKYSPVPETISVPKGTDLSgrAKDGIANADKdangkekLPDGTKYEWDGGvPNTSVTNNKYGHVKVTYPDGSSTVVEV 1224
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD--AEDGIKNKDD-------LPEGTKYTWKTP-PDTTTPGDKTGTVVVTYPDGSTDEVEV 70


                   ....*.
gi 1828715824 1225 PLNITD 1230
Cdd:pfam08428   71 TVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1668-1757 2.29e-12

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 64.17  E-value: 2.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1668 DADRNTPETQTIKTLPGQTVNPEDGVinlhkpgENNPQLPDGTKVTFDNQSDVDDftkhgmPGsDKSFDATVTYPDGTTD 1747
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGI-------KNKDDLPEGTKYTWKTPPDTTT------PG-DKTGTVVVTYPDGSTD 66

                           90
                   ....*....|
gi 1828715824 1748 KIKLPVHITA 1757
Cdd:pfam08428   67 EVEVTVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1316-1402 1.06e-10

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 59.55  E-value: 1.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1316 DASKYGIETQEINVHEGTDISsdewARKGILNADQagkqneqLPDGTSYTWANGnvPDTTKPNKKTGYVTVTFPDNSSRT 1395
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD----AEDGIKNKDD-------LPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDE 67


                   ....*..
gi 1828715824 1396 VPVIVNV 1402
Cdd:pfam08428   68 VEVTVTV 74
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1092-1151 1.62e-10

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 59.12  E-value: 1.62e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824 1092 KDKSTNLPTDP--SAYTWVNGA-PDTSKTGDIPATVKVTYPDGSYNTVDVTVHVT---SDAEKYSP 1151
Cdd:TIGR02331   13 SDSITNLVDLPdgTTYVWKTVNtPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTpprTDADKYDP 78
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1758-1851 1.62e-10

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 59.16  E-value: 1.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1758 DNEVNTPITQGIITPKDSVPDANKGIANLkkattkegktyPALPENTTVEWVNPGQMKTElenakggTTKNYDAVVIYPD 1837
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNK-----------DDLPEGTKYTWKTPPDTTTP-------GDKTGTVVVTYPD 62

                           90
                   ....*....|....
gi 1828715824 1838 KSTEIVSIPVTVAT 1851
Cdd:pfam08428   63 GSTDEVEVTVTVTD 76
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1344-1413 8.25e-10

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 57.19  E-value: 8.25e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1344 GILNADQAGKQNEQLPDGTSYTWANGNVPDTTKPNKKTGYVTVTFPDNSSRTVPVIVNVIgDGRSDAEKY 1413
Cdd:TIGR02331    8 GTPDASDSITNLVDLPDGTTYVWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVT-PPRTDADKY 76
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 2042-2107 1.86e-09

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 56.42  E-value: 1.86e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824 2042 TDKNGQLPNAKEGIKNLADLPEGTNPTWadRAQDKINKTKPGtDTTAQVVVTFPDGSTKEVTVPVH 2107
Cdd:TIGR02331    3 TVEVGGTPDASDSITNLVDLPDGTTYVW--KTVNTPDTNTPG-DKPAVVVVTYPDGTKDTVPVTVH 65
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1168-1241 2.30e-09

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 56.04  E-value: 2.30e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824 1168 AKDGIANadkdangKEKLPDGTKYEW-DGGVPNTSVTNNKYGHVKVTYPDGSSTVVEVPLNITDnNKSDAEKHNP 1241
Cdd:TIGR02331   12 ASDSITN-------LVDLPDGTTYVWkTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTP-PRTDADKYDP 78
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1092-1143 1.04e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 53.77  E-value: 1.04e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1828715824 1092 KDKSTNLPTDPSA--YTWVNgAPDTSKTGDIPATVKVTYPDGSYNTVDVTVHVT 1143
Cdd:pfam08428   23 EDGIKNKDDLPEGtkYTWKT-PPDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75
hyperosmo_Ebh TIGR04264
hyperosmolarity resistance protein Ebh, N-terminal domain; Staphylococcal protein Ebh ...
 797-1368 1.09e-08

hyperosmolarity resistance protein Ebh, N-terminal domain; Staphylococcal protein Ebh (extracellular matrix-binding protein homolog) is a giant protein, sometimes over 10,000 amino acids long as reported. This model describes a non-repetitive amino-terminal domain of about 2400 amino acids.


Pssm-ID: 275090 [Multi-domain]  Cd Length: 2354  Bit Score: 61.01  E-value: 1.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  797 VSTTAplgpTAKSPITVAKDDNLA--GQDASQYITNKDEIANIKPGTT-----DYEPTFKSAAWKSVDTNTKKGIITVTY 869
Cdd:TIGR04264 1408 VTTSS----TEQNPIRIANIRNNAtlSQADKQAIINSLTITNNIPNRNyvtagANEIRSKEVSNVSRTGNNANVTVTITY 1483

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  870 ADNTTTDLDVDL-NVVDKITDADKFTPEGGTIKVDNghkldGNDAYEAIKNHDDLPADKAGYNWVVDeNHPAVDTTKPG- 947
Cdd:TIGR04264 1484 ADGTTSQITVPVkHVIPEIVAIPRYTVQGQNFPAGK-----GANPNDFFKLNNGSPVPDATITWVNG-NGPNINSTRIGv 1557

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  948 DQTgyvqvtyndgsksdlvpVTVHVIADNEKyTAIGKTQNLQKGQSANPQDFIANKDGEV-----SQDGKTYTK-----L 1017
Cdd:TIGR04264 1558 DIT-----------------VRANILFDGET-TPIEKEASYMVVKSVPKRVFETTRNGNFpginnSYNPGSYVQpinnsW 1619

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1018 PDGTK---YEWVDG--GIDTSTIGPKQAQVKVTYPDGTTQIVPVKANVYSDA----NLSTVvgkdinagYKEDLTNRAID 1088
Cdd:TIGR04264 1620 PQGAQamnFDFGPNsgGPNSNVVGIFTRTIRVTYPNGQVENVKVLAKVKPDPpridSNSVT--------YKAGLTNQQIK 1691

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1089 ----------AIDKDKSTNLPTDPSAYTWVNGA----PDTSKTGDIPATVKVTYPDGSYNT-------VDVTVHVTSDAE 1147
Cdd:TIGR04264 1692 vnnvlnnspvKLYKSDGTELTNTTTTYGSNGSAtvtvSGALPLGNIKAKSSITVNNVTYTTqnnsgqvVNVTRNESVESD 1771

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1148 KYSPVPETISVPKGTDLSGRAKDGIANADKDANGK-EKLPDGTKYEWDGGvPNT--SVTNNKYGHVKVTYPDGSST-VVE 1223
Cdd:TIGR04264 1772 DSAPVRVTPQLHATNGGAKFVKGGDNFDFNNAARYiDNLPDGATVEWEDN-PDTwkNTVGNTTKTAVVTLPNGQGTrTVN 1850

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1224 VPLNITDNNKSDAEKHNPQANilhatlnqDLSSNDWAKKGIL--NADEQDGATFRWRKGYVPDTSKEGQVWGIVVVSYPD 1301
Cdd:TIGR04264 1851 IPVKVYPVATAKAPQRDVKGH--------QLTYGTDAMNYVTfePNTNMNGITATWKNNNQPNNNQAGVQNLTANVTYPG 1922

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1302 SSiNEVRVPVIVqsDASKYGIETQEINVHEGTDISSDEWARK--GILNADqagkqneQLP-DGTSYTWAN 1368
Cdd:TIGR04264 1923 IS-TPYRVPVKV--YVYKFDFAQSEYTTTVGTTFAGGTNVNNyvHLENAN-------GLPtDGFHYVWNQ 1982
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1508-1576 3.04e-08

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 52.96  E-value: 3.04e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1828715824 1508 AADGIANKDQMPVAnkpegtvhTTYSWKDNIIPDTTKPGTKYGIVEVNFPDGSTKDVPVEVKVTSLASD 1576
Cdd:TIGR02331   12 ASDSITNLVDLPDG--------TTYVWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTPPRTD 72
aRib pfam18938
Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a ...
 2201-2269 4.43e-08

Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a variety of bacterial cell surface proteins. These proteins share a conserved motif with the Rib domain (YPDXXD). The structure of the aRib domain has been solved from two proteins, the SrpA adhesin and the GspB adhesin. In these proteins this domain has been termed the unique domain due to its lack of similarity to any other known structures at the time. The aRib domain from SrpA has been shown to mediate a dimer interaction. This family has been added to the E-set clan based on its similarity to the Rib domain, although it does not contain the Ig fold.


Pssm-ID: 465921 [Multi-domain]  Cd Length: 71  Bit Score: 51.84  E-value: 4.43e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 2201 TLNPPTdKVPVDDTKHITDEDKGKVIDNVKKSNPDK-DITDAHVDDDG--TFHGKvDGQDVVIPGTETVVEK 2269
Cdd:pfam18938    2 TINIPE-KTEVKDPNKLTDEEKQEVKDAVKKANPDLpEGTKVEVDDDGtvTVTYP-DGSKDTIPAKDLVKEK 71
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1235-1313 4.59e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 52.23  E-value: 4.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1235 DAEKHNPQANILHATLNQDLSsndwAKKGILNADE-QDGATFRWRKGyvPDTSKEGQVWGIVVVSYPDSSINEVRVPVIV 1313
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD----AEDGIKNKDDlPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVEVTVTV 74
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1946-2025 9.37e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 51.07  E-value: 9.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1946 QSDDYNIETQPVNTDKdGNLPeNADSGIKNLGKLPEGTHASWgdgaQDIAKNLKPGeTKDVPATVVFPDGSKKEITIPVH 2025
Cdd:pfam08428    1 DADKYTPKGKDITVEV-GETP-DAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTVT 73
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 2135-2191 1.19e-07

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 51.07  E-value: 1.19e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1828715824 2135 NADSGIKNLGDLPEGTHAVWgqgaQTIVDGMKPGeTKDVPATIEFPDGSTKDVTIPV 2191
Cdd:pfam08428   21 DAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTV 72
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 912-983 2.56e-07

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 50.26  E-value: 2.56e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824  912 DAYEAIKNHDDLPaDKAGYNWvvdENHPAVDTTKPGDQTGYVQVTYNDGSKsDLVPVTVHVI---ADNEKYTAIG 983
Cdd:TIGR02331   11 DASDSITNLVDLP-DGTTYVW---KTVNTPDTNTPGDKPAVVVVTYPDGTK-DTVPVTVHVTpprTDADKYDPAG 80
aRib pfam18938
Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a ...
 2273-2341 2.74e-07

Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a variety of bacterial cell surface proteins. These proteins share a conserved motif with the Rib domain (YPDXXD). The structure of the aRib domain has been solved from two proteins, the SrpA adhesin and the GspB adhesin. In these proteins this domain has been termed the unique domain due to its lack of similarity to any other known structures at the time. The aRib domain from SrpA has been shown to mediate a dimer interaction. This family has been added to the E-set clan based on its similarity to the Rib domain, although it does not contain the Ig fold.


Pssm-ID: 465921 [Multi-domain]  Cd Length: 71  Bit Score: 49.91  E-value: 2.74e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 2273 SLNPPTdKVPVDDTKHITDEDKGKVIDNVKKSNPDK-DITDAHVDDDG--TFHGKvDGQDVVIPGIETVVEK 2341
Cdd:pfam18938    2 TINIPE-KTEVKDPNKLTDEEKQEVKDAVKKANPDLpEGTKVEVDDDGtvTVTYP-DGSKDTIPAKDLVKEK 71
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1679-1764 3.71e-07

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 49.87  E-value: 3.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1679 IKTLPGQTVNPEDGVINLhkpgennPQLPDGTKVTFDNQSDVDDFTkhgmPGsDKSFDATVTYPDGTTDKIKLPVHIT-- 1756
Cdd:TIGR02331    2 ETVEVGGTPDASDSITNL-------VDLPDGTTYVWKTVNTPDTNT----PG-DKPAVVVVTYPDGTKDTVPVTVHVTpp 69


                   ....*....
gi 1828715824 1757 -ADNEVNTP 1764
Cdd:TIGR02331   70 rTDADKYDP 78
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 823-897 6.42e-07

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 49.10  E-value: 6.42e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1828715824  823 DASQYITNKDEIanikPGTTDYEPTfksaAWKSVDTNT---KKGIITVTYADNTTTDLDVDLNVVDKITDADKFTPEG 897
Cdd:TIGR02331   11 DASDSITNLVDL----PDGTTYVWK----TVNTPDTNTpgdKPAVVVVTYPDGTKDTVPVTVHVTPPRTDADKYDPAG 80
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 118-634 2.17e-06

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 53.24  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  118 TQDRTDSNDNATTNQVDTTQVSTTSLKAVQSSNQAANLLAESKVEDSTTANVSDFDSFNSALMNQNITTININSDFTSGN 197
Cdd:COG4625     23 GGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGTGGVGGGGGGGGG 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  198 YGTNVEHRRVVPRTLVINGNGHTVDLGSIGYFMNPGGNQAADWTVENGTFYSKSAVGPFALTGDHGTDKAWQATNGAVHR 277
Cdd:COG4625    103 GGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGG 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  278 MTYKDMTVYAGGGAYAANAEIDLEGTNNLNATASYQSKFSNGTVYTETGGNRSGVEGQWIIIKDNANVTVNTDHGQAIST 357
Cdd:COG4625    183 GGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGG 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  358 EYSDGNHRIEVGENATLNGNYLYTTYGTPYGGGKIPVLSNGANGGTVIFHKGSKSHFTMPNQNVTGFGGNGFSNYGT--- 434
Cdd:COG4625    263 GAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGsgg 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  435 GSVLYLGAANTTIEKGAEVTIDNPKEANNDNSIFIRSDGTQLNIFGNLIINDGARDYTIRADNRVSINVGQSIADDDYSN 514
Cdd:COG4625    343 AGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGG 422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  515 DNGKLIINRNGDFYLNNDGGALSMWGPITINVNSGAALEVYSTGINNVSGSGANPALMRVGGSSKLNVYKRGTFILSDSS 594
Cdd:COG4625    423 GGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGS 502

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1828715824  595 NGKVSL----VDDYNANGNFNFDNTAKVIFDISNNNNQNSRIFA 634
Cdd:COG4625    503 TLAVEVdaanSDRLVVTGTATLNGGTVVVLAGGYAPGTTYTILA 546
Gram_pos_anchor pfam00746
LPXTG cell wall anchor motif;
2382-2419 1.12e-05

LPXTG cell wall anchor motif;


Pssm-ID: 366278 [Multi-domain]  Cd Length: 43  Bit Score: 44.45  E-value: 1.12e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1828715824 2382 KQNRLPQTGSE-TSGLSALGLAMLsLVGLGFLIKKRKED 2419
Cdd:pfam00746    5 KKKTLPKTGENsNIFLTAAGLLAL-LGGLLLLVKRRKKE 42
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1427-1493 1.93e-05

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 44.87  E-value: 1.93e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 1427 TPVAEKAVSNLDELKDVSSITWAT--TPDVSKVGNVPAIVVVTYKDGTSNAAPINIEV---KGLANDYKPEG 1493
Cdd:TIGR02331    9 TPDASDSITNLVDLPDGTTYVWKTvnTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVtppRTDADKYDPAG 80
YSIRK_signal pfam04650
YSIRK type signal peptide; Many surface proteins found in Streptococcus, Staphylococcus, and ...
 17-42 2.20e-05

YSIRK type signal peptide; Many surface proteins found in Streptococcus, Staphylococcus, and related lineages share apparently homologous signal sequences. A motif resembling [YF]SIRKxxxGxxS[VIA] appears at the start of the transmembrane domain. The GxxS motif appears perfectly conserved, suggesting a specific function and not just homology. There is a strong correlation between proteins carrying this region at the N-terminus and those carrying the Gram-positive anchor domain with the LPXTG sortase processing site at the C-terminus.


Pssm-ID: 428049 [Multi-domain]  Cd Length: 26  Bit Score: 43.14  E-value: 2.20e-05
                           10        20
                   ....*....|....*....|....*.
gi 1828715824   17 KEQQHFALRKLNVGLVSVLMGTTLFF 42
Cdd:pfam04650    1 EKKQRYSIRKLSVGVASVLIGTLLFL 26
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 2385-2417 1.25e-04

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 40.92  E-value: 1.25e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1828715824 2385 RLPQTGSE-TSGLSALGLAMLSLVGLGFLIKKRK 2417
Cdd:TIGR01167    1 KLPKTGESgNSLLLLLGLLLLGLGGLLLRKRKKK 34
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1260-1320 1.36e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 42.56  E-value: 1.36e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824 1260 AKKGILNADE-QDGATFRWRKGYVPDTSKEGQVWGIVVVSYPDSSINEVRVPVIVQ---SDASKY 1320
Cdd:TIGR02331   12 ASDSITNLVDlPDGTTYVWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTpprTDADKY 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1587-1667 2.28e-04

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 41.83  E-value: 2.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1587 IAKYKGNIPQASDGIANKDqatkegdkdfpslaDVLAPNGIQWKKNfePDLSKPGLTSGEAILTFKDGSTAEVTIPVLVQ 1666
Cdd:pfam08428   12 ITVEVGETPDAEDGIKNKD--------------DLPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75


                   .
gi 1828715824 1667 T 1667
Cdd:pfam08428   76 D 76
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 17-203 2.39e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.44  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824   17 KEQQHFALRKLNVGLVSVLMGTTLFFvGQTSIAKADTLESTKTsvteiSSSSNSNQEKLEQAKAVSSQEQTTSTEENVDS 96
Cdd:NF033609     4 KKKEKHAIRKKSIGVASVLVGTLIGF-GLLSSKEADASENSVT-----QSDSASNESKSNDSSSVSAAPKTDDTNVSDTK 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824   97 ASSSQSKSENNSSSSAKSEVSTQdrtDSNDNATTNQVDTTQVSTTSLK-------AVQSSNQAANLLAESKVEDSTTANV 169
Cdd:NF033609    78 TSSNTNNGETSVAQNPAQQETTQ---SASTNATTEETPVTGEATTTATnqantpaTTQSSNTNAEELVNQTSNETTSNDT 154

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1828715824  170 SDFDSFNSALMNQNITTININSDFTSGNYGTNVE 203
Cdd:NF033609   155 NTVSSVNSPQNSTNAENVSTTQDTSTEATPSNNE 188
YSIRK_signal TIGR01168
Gram-positive signal peptide, YSIRK family; Many surface proteins found in Streptococcus, ...
 17-45 2.47e-04

Gram-positive signal peptide, YSIRK family; Many surface proteins found in Streptococcus, Staphylococcus, and related lineages share apparently homologous signal sequences. A motif resembling [YF]SIRKxxxGxxS[VIA] appears at the start of the transmembrane domain. The GxxS motif appears perfectly conserved, suggesting a specific function and not just homology. There is a strong correlation between proteins carrying this region at the N-terminus and those carrying the Gram-positive anchor domain with the LPXTG sortase processing site at the C-terminus.


Pssm-ID: 273479 [Multi-domain]  Cd Length: 39  Bit Score: 40.54  E-value: 2.47e-04
                           10        20
                   ....*....|....*....|....*....
gi 1828715824   17 KEQQHFALRKLNVGLVSVLMGtTLFFVGQ 45
Cdd:TIGR01168    6 EKQQKYSIRKLSVGVASVLVA-SLFFGGG 33
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1768-1856 3.41e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 41.40  E-value: 3.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1768 GIITPKDSVPDANKGIANLkkattkegktyPALPENTTVEWVNPGQMKTELENAKGGTTknydaVVIYPDKSTEIVSIPV 1847
Cdd:TIGR02331    1 GETVEVGGTPDASDSITNL-----------VDLPDGTTYVWKTVNTPDTNTPGDKPAVV-----VVTYPDGTKDTVPVTV 64

                           90
                   ....*....|..
gi 1828715824 1848 TV---ATDADTY 1856
Cdd:TIGR02331   65 HVtppRTDADKY 76
Big_6 pfam17936
Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial ...
 726-803 5.10e-04

Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.


Pssm-ID: 465576 [Multi-domain]  Cd Length: 83  Bit Score: 41.07  E-value: 5.10e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1828715824  726 FTDNGAQIKGSvvdesTNTGAVAVAYDKDNNKVGSGNVDDQGNFTINLDKPLLNKEEVKVrieTPRGASGFVSTTAPL 803
Cdd:pfam17936   10 VSDDGTTLTGT-----GEAGATVTVKDADGNVLGTGTVDADGTFSVTLDPAQANGETLSV---TATDAAGNVSPAATI 79
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1591-1676 6.97e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 40.63  E-value: 6.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1591 KGNIPQASDGIANKDqatkegdkDFPSLADVlapngiQWKKNFEPDLSKPGLTSGEAILTFKDGSTAEVTIPVLVQ---T 1667
Cdd:TIGR02331    6 VGGTPDASDSITNLV--------DLPDGTTY------VWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTpprT 71


                   ....*....
gi 1828715824 1668 DADRNTPET 1676
Cdd:TIGR02331   72 DADKYDPAG 80
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 2124-2206 8.65e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 40.24  E-value: 8.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 2124 VETDSHGQLPEnADSGIKNLGDLPEGTHAVWGQGAQtiVDGMKPGEtKDVPATIEFPDGSTKDVTIPVYKTSTRDQGTLN 2203
Cdd:TIGR02331    1 GETVEVGGTPD-ASDSITNLVDLPDGTTYVWKTVNT--PDTNTPGD-KPAVVVVTYPDGTKDTVPVTVHVTPPRTDADKY 76


                   ...
gi 1828715824 2204 PPT 2206
Cdd:TIGR02331   77 DPA 79
YPDG_rpt NF038186
YPDG domain; The YPDG domain may occur once in a protein, or up to 22 times in tandem repeats. ...
 1111-1142 1.23e-03

YPDG domain; The YPDG domain may occur once in a protein, or up to 22 times in tandem repeats. It is common in proteins of Gram-positive bacteria with C-terminal LPXTG sites for anchoring on the cell surface.


Pssm-ID: 439498 [Multi-domain]  Cd Length: 98  Bit Score: 40.43  E-value: 1.23e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1828715824 1111 APDTSKTGD-IPATVKVTYPDGSYNTVDVTVHV 1142
Cdd:NF038186    66 APEDAKPGDeVTVPVTVTYPDGSTDEVPATVTV 98
Ig_like_BLP2 NF040520
Ig-like repeat protein Blp2; Blp2 (BAP-like protein 2), found broadly in the genus ...
 752-807 2.90e-03

Ig-like repeat protein Blp2; Blp2 (BAP-like protein 2), found broadly in the genus Acinetobacter, resembles the much larger biofilm-associated proteins Bap and Blp1 in N-terminal sequence and the presence of tandem Ig-like repeats.


Pssm-ID: 468522 [Multi-domain]  Cd Length: 729  Bit Score: 43.10  E-value: 2.90e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824  752 DKDNNKVGSGNVDDQGNFTINLDKPLLNKEEVKVrieTPRGASGFVS----------TTAPLGPTA 807
Cdd:NF040520   197 DATGKVIATGQADASGNYTIKLDQPLVNGNKVNV---TAIDAAGNASkatvvtgtkdTIAPDAPQA 259
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 27-1181 5.03e-03

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 42.45  E-value: 5.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824   27 LNVGLVSVLMGTTLFFVGQTSIAKADTLESTKTSVTEISSSSNSNQEKLEQAKAVSSQEQTTSTEENVDSASSSQSKSEN 106
Cdd:COG3210    531 GTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGA 610

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  107 NSSSSAKSEVSTQDRTDSNDNATTNQVDTTQVSTTSLKAVQSSNQAANLLAESKVEDSTTANVSDFDSFNSALMNQNITT 186
Cdd:COG3210    611 TGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTT 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  187 ININSDFTSGNYGTNVEHRRVVPRTLVINGNGHTVDLGSIGYFMNPGGNQA---ADWTVENGTFYSKSAVGPFALTGDhG 263
Cdd:COG3210    691 LNAATGGTLNNAGNTLTISTGSITVTGQIGALANANGDTVTFGNLGTGATLtlnAGVTITSGNAGTLSIGLTANTTAS-G 769

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  264 TDKAWQATNGAVHRMTYKDMTVYAGGGAYAANAEIDLEGTNNLNATASYQS-KFSNGTVYTETGGNRSGVEGQWIIIKDN 342
Cdd:COG3210    770 TTLTLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSGGTiTINTATTGLTGTGDTTSGAGGSNTTDTT 849

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  343 ANVTVNTDHGQAISTEYSDGNHRIEVGENATLNGNYLYTTYGTPYGGGKIPVLSNGANGGTVIFHKGSKSHFTMPNQNVT 422
Cdd:COG3210    850 TGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGG 929

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  423 GFGGNGFSNYGTGSVLYLGAANTTIEKGAEVTIDNPKEANNDNSIFIRSDGTQLNIFGNLIINDGARDYTIRADNRVSIN 502
Cdd:COG3210    930 NAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTT 1009

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  503 VGQSIADDDYSNDNGKLIINRNGDFYLNNDGGALSMWGPITINVNSGAALEVYSTGINNVSGSGANPALMRVGGSSKLNV 582
Cdd:COG3210   1010 GGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAG 1089

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  583 YKRGTFILSDSSNGKVSLVDDYNANGNFNFDNTAKVIFDISNNNNQNSRIFALNGTVYATHDKVRAMLTPSSNIADMGTF 662
Cdd:COG3210   1090 TTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAV 1169

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  663 KTVQFNTSGQGGVTGDALHSEYQNQAYNNIVAIRDAIRTGQLRYLEFSTRSVNNASITGEGHGFTDNGAQIKGSVVDEST 742
Cdd:COG3210   1170 AAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGS 1249

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  743 NTGAVAVAYDKDNNKVGSGNVDDQGNFTINLDKPLLNKEEVKVRIETPRGASGFVSTTAPLGPTAKSPITVAKDDNLAGQ 822
Cdd:COG3210   1250 ASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTGNTAGANGATVGTGIGGTTATGTAVA 1329

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  823 DASQYITNKDEIANIKPGTTDYEPTFKSAA--WKSVDTNTKKGIITVTYADNTTTDLDVDLNVVDKITDADKFTPEGGTI 900
Cdd:COG3210   1330 AVNSGGVNAGGGTINTTAANTGLNGGNGATdsAAGAGSGGAAGSLAATAGAGTVLTGAGNNTGAEGTNAGRDGGVTTSGT 1409

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  901 KVDNGHKLDGNDAYEAIKNHDDLPADKAGYNWVVDENHPAVDTTKPGDQTGYVQVTYNDGSKSDLVPVTVHVIADNEKYT 980
Cdd:COG3210   1410 GVGNNGGVSGTTVAGTTGSSATTGTGGTGNTTGTSVAGAGGGNADASAINTGNASSLGAGGSTAGNAVGGAVIGGTTTGG 1489

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  981 AIGKTQNLQKGQSANPQDFIANKDGEVSQDGKTYTKLPDGTKYEWVDGGIDTSTIGPKQAQVKVTYPDGTTQIVPVKANV 1060
Cdd:COG3210   1490 NGAGVAGATASNGGTSTGAGGTAGGTTAEVAKASLEGGEGTYGGSSVAEAGTGGGILGAVSGAGSEGGAAGGVTGSVGVG 1569

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1061 YSDANLSTVVGKDINAGYKEDLTNRAIDAIDKDKSTNLPTDPSAYTWVNGAPDTSKTGDIPATVKVTYPDGSYNTVDVTV 1140
Cdd:COG3210   1570 GTDGAGGDTGGADDTGAQAPTAGNTATLTLSLAEGTNAEYGGTTNVTSGTAGNAGATGANSNTVVTTNGGEGVLALVAGG 1649

                         1130      1140      1150      1160
                   ....*....|....*....|....*....|....*....|.
gi 1828715824 1141 HVTSDAEKYSPVPETISVPKGTDLSGRAKDGIANADKDANG 1181
Cdd:COG3210   1650 NTTNGTTLSGAVNGAGNGWAVDLTDATLAGLGGATTAAAGN 1690
 
Name Accession Description Interval E-value
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 975-1060 8.15e-15

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 71.10  E-value: 8.15e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  975 DNEKYTAIGKTQNLQKGQSANPQDFIANKDgevsqdgktytKLPDGTKYEWVDGgIDTSTIGPKQAQVKVTYPDGTTQIV 1054
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNKD-----------DLPEGTKYTWKTP-PDTTTPGDKTGTVVVTYPDGSTDEV 68


                   ....*.
gi 1828715824 1055 PVKANV 1060
Cdd:pfam08428   69 EVTVTV 74
Pectate_lyase_5 pfam20585
Putative pectate lyase-like adhesive domain; This putative domain is found at the N-terminus ...
 166-284 1.37e-14

Putative pectate lyase-like adhesive domain; This putative domain is found at the N-terminus of a large number of bacterial proteins. Its adhesive function was described in Lactobacillus reuteri serine-rich repeat proteins. Structure predictions show it is composed of a beta solenoid repeat related to Pectate lyase.


Pssm-ID: 466734  Cd Length: 126  Bit Score: 72.45  E-value: 1.37e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  166 TANVSDFDSFNSALMNQNITTININSDFTSGNYGTNVEHRRVVP---RTLVINGNGHTVDLGSIGY-FMNPGGNQAADW- 240
Cdd:pfam20585    1 TVEVSTWAEFKAALNDANVTTINLTADITVTSAGGGGYVYLTTSniaRSLTIDGNGHTLDFGARAInFYDINVKTANSWd 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1828715824  241 -TVENGTFYSKSAVGPFALTGDhgtdkawQATNGAVHRMTYKDMT 284
Cdd:pfam20585   81 iTLENLTITNGNYYGFFWSNDL-------NTDNQAGSTVTYKNVT 118
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 889-974 5.10e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 69.18  E-value: 5.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  889 DADKFTPEGGTIKVDNGHKLDgndAYEAIKNHDDLPADKAgYNWVVdenhpAVDTTKPGDQTGYVQVTYNDGSKsDLVPV 968
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD---AEDGIKNKDDLPEGTK-YTWKT-----PPDTTTPGDKTGTVVVTYPDGST-DEVEV 70


                   ....*.
gi 1828715824  969 TVHVIA 974
Cdd:pfam08428   71 TVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 2029-2107 5.30e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.79  E-value: 5.30e-14
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1828715824 2029 QSDGYDVEPQLVNTDKnGQLPNAKEGIKNLADLPEGTNPTWadraQDKINKTKPGtDTTAQVVVTFPDGSTKEVTVPVH 2107
Cdd:pfam08428    1 DADKYTPKGKDITVEV-GETPDAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTVT 73
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1486-1571 7.10e-14

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.79  E-value: 7.10e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1486 ANDYKPEGTTIYAGLNEDITnrAADGIANKDQMPVAnkpegtvhTTYSWKDNiiPDTTKPGTKYGIVEVNFPDGSTKDVP 1565
Cdd:pfam08428    2 ADKYTPKGKDITVEVGETPD--AEDGIKNKDDLPEG--------TKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVE 69


                   ....*.
gi 1828715824 1566 VEVKVT 1571
Cdd:pfam08428   70 VTVTVT 75
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1409-1483 1.23e-13

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 68.02  E-value: 1.23e-13
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824 1409 DAEKYQLKAHDIWTYINDTPVAEKAVSNLDELKDVSSITWATTPDVSKVGNVPAIVVVTYKDGTSNAAPINIEVK 1483
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNKDDLPEGTKYTWKTPPDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1145-1230 7.67e-13

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 65.71  E-value: 7.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1145 DAEKYSPVPETISVPKGTDLSgrAKDGIANADKdangkekLPDGTKYEWDGGvPNTSVTNNKYGHVKVTYPDGSSTVVEV 1224
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD--AEDGIKNKDD-------LPEGTKYTWKTP-PDTTTPGDKTGTVVVTYPDGSTDEVEV 70


                   ....*.
gi 1828715824 1225 PLNITD 1230
Cdd:pfam08428   71 TVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1668-1757 2.29e-12

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 64.17  E-value: 2.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1668 DADRNTPETQTIKTLPGQTVNPEDGVinlhkpgENNPQLPDGTKVTFDNQSDVDDftkhgmPGsDKSFDATVTYPDGTTD 1747
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGI-------KNKDDLPEGTKYTWKTPPDTTT------PG-DKTGTVVVTYPDGSTD 66

                           90
                   ....*....|
gi 1828715824 1748 KIKLPVHITA 1757
Cdd:pfam08428   67 EVEVTVTVTD 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1316-1402 1.06e-10

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 59.55  E-value: 1.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1316 DASKYGIETQEINVHEGTDISsdewARKGILNADQagkqneqLPDGTSYTWANGnvPDTTKPNKKTGYVTVTFPDNSSRT 1395
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD----AEDGIKNKDD-------LPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDE 67


                   ....*..
gi 1828715824 1396 VPVIVNV 1402
Cdd:pfam08428   68 VEVTVTV 74
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1092-1151 1.62e-10

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 59.12  E-value: 1.62e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824 1092 KDKSTNLPTDP--SAYTWVNGA-PDTSKTGDIPATVKVTYPDGSYNTVDVTVHVT---SDAEKYSP 1151
Cdd:TIGR02331   13 SDSITNLVDLPdgTTYVWKTVNtPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTpprTDADKYDP 78
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1758-1851 1.62e-10

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 59.16  E-value: 1.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1758 DNEVNTPITQGIITPKDSVPDANKGIANLkkattkegktyPALPENTTVEWVNPGQMKTElenakggTTKNYDAVVIYPD 1837
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPDAEDGIKNK-----------DDLPEGTKYTWKTPPDTTTP-------GDKTGTVVVTYPD 62

                           90
                   ....*....|....
gi 1828715824 1838 KSTEIVSIPVTVAT 1851
Cdd:pfam08428   63 GSTDEVEVTVTVTD 76
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1344-1413 8.25e-10

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 57.19  E-value: 8.25e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1344 GILNADQAGKQNEQLPDGTSYTWANGNVPDTTKPNKKTGYVTVTFPDNSSRTVPVIVNVIgDGRSDAEKY 1413
Cdd:TIGR02331    8 GTPDASDSITNLVDLPDGTTYVWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVT-PPRTDADKY 76
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 2042-2107 1.86e-09

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 56.42  E-value: 1.86e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824 2042 TDKNGQLPNAKEGIKNLADLPEGTNPTWadRAQDKINKTKPGtDTTAQVVVTFPDGSTKEVTVPVH 2107
Cdd:TIGR02331    3 TVEVGGTPDASDSITNLVDLPDGTTYVW--KTVNTPDTNTPG-DKPAVVVVTYPDGTKDTVPVTVH 65
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1168-1241 2.30e-09

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 56.04  E-value: 2.30e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824 1168 AKDGIANadkdangKEKLPDGTKYEW-DGGVPNTSVTNNKYGHVKVTYPDGSSTVVEVPLNITDnNKSDAEKHNP 1241
Cdd:TIGR02331   12 ASDSITN-------LVDLPDGTTYVWkTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTP-PRTDADKYDP 78
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1092-1143 1.04e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 53.77  E-value: 1.04e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1828715824 1092 KDKSTNLPTDPSA--YTWVNgAPDTSKTGDIPATVKVTYPDGSYNTVDVTVHVT 1143
Cdd:pfam08428   23 EDGIKNKDDLPEGtkYTWKT-PPDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75
hyperosmo_Ebh TIGR04264
hyperosmolarity resistance protein Ebh, N-terminal domain; Staphylococcal protein Ebh ...
 797-1368 1.09e-08

hyperosmolarity resistance protein Ebh, N-terminal domain; Staphylococcal protein Ebh (extracellular matrix-binding protein homolog) is a giant protein, sometimes over 10,000 amino acids long as reported. This model describes a non-repetitive amino-terminal domain of about 2400 amino acids.


Pssm-ID: 275090 [Multi-domain]  Cd Length: 2354  Bit Score: 61.01  E-value: 1.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  797 VSTTAplgpTAKSPITVAKDDNLA--GQDASQYITNKDEIANIKPGTT-----DYEPTFKSAAWKSVDTNTKKGIITVTY 869
Cdd:TIGR04264 1408 VTTSS----TEQNPIRIANIRNNAtlSQADKQAIINSLTITNNIPNRNyvtagANEIRSKEVSNVSRTGNNANVTVTITY 1483

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  870 ADNTTTDLDVDL-NVVDKITDADKFTPEGGTIKVDNghkldGNDAYEAIKNHDDLPADKAGYNWVVDeNHPAVDTTKPG- 947
Cdd:TIGR04264 1484 ADGTTSQITVPVkHVIPEIVAIPRYTVQGQNFPAGK-----GANPNDFFKLNNGSPVPDATITWVNG-NGPNINSTRIGv 1557

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  948 DQTgyvqvtyndgsksdlvpVTVHVIADNEKyTAIGKTQNLQKGQSANPQDFIANKDGEV-----SQDGKTYTK-----L 1017
Cdd:TIGR04264 1558 DIT-----------------VRANILFDGET-TPIEKEASYMVVKSVPKRVFETTRNGNFpginnSYNPGSYVQpinnsW 1619

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1018 PDGTK---YEWVDG--GIDTSTIGPKQAQVKVTYPDGTTQIVPVKANVYSDA----NLSTVvgkdinagYKEDLTNRAID 1088
Cdd:TIGR04264 1620 PQGAQamnFDFGPNsgGPNSNVVGIFTRTIRVTYPNGQVENVKVLAKVKPDPpridSNSVT--------YKAGLTNQQIK 1691

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1089 ----------AIDKDKSTNLPTDPSAYTWVNGA----PDTSKTGDIPATVKVTYPDGSYNT-------VDVTVHVTSDAE 1147
Cdd:TIGR04264 1692 vnnvlnnspvKLYKSDGTELTNTTTTYGSNGSAtvtvSGALPLGNIKAKSSITVNNVTYTTqnnsgqvVNVTRNESVESD 1771

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1148 KYSPVPETISVPKGTDLSGRAKDGIANADKDANGK-EKLPDGTKYEWDGGvPNT--SVTNNKYGHVKVTYPDGSST-VVE 1223
Cdd:TIGR04264 1772 DSAPVRVTPQLHATNGGAKFVKGGDNFDFNNAARYiDNLPDGATVEWEDN-PDTwkNTVGNTTKTAVVTLPNGQGTrTVN 1850

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1224 VPLNITDNNKSDAEKHNPQANilhatlnqDLSSNDWAKKGIL--NADEQDGATFRWRKGYVPDTSKEGQVWGIVVVSYPD 1301
Cdd:TIGR04264 1851 IPVKVYPVATAKAPQRDVKGH--------QLTYGTDAMNYVTfePNTNMNGITATWKNNNQPNNNQAGVQNLTANVTYPG 1922

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1302 SSiNEVRVPVIVqsDASKYGIETQEINVHEGTDISSDEWARK--GILNADqagkqneQLP-DGTSYTWAN 1368
Cdd:TIGR04264 1923 IS-TPYRVPVKV--YVYKFDFAQSEYTTTVGTTFAGGTNVNNyvHLENAN-------GLPtDGFHYVWNQ 1982
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1508-1576 3.04e-08

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 52.96  E-value: 3.04e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1828715824 1508 AADGIANKDQMPVAnkpegtvhTTYSWKDNIIPDTTKPGTKYGIVEVNFPDGSTKDVPVEVKVTSLASD 1576
Cdd:TIGR02331   12 ASDSITNLVDLPDG--------TTYVWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTPPRTD 72
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 986-1060 3.76e-08

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 52.57  E-value: 3.76e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824  986 QNLQKGQSANPQDFIANKDgevsqdgktytKLPDGTKYEWVDGG-IDTSTIGPKQAQVKVTYPDGTTQIVPVKANV 1060
Cdd:TIGR02331    2 ETVEVGGTPDASDSITNLV-----------DLPDGTTYVWKTVNtPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHV 66
aRib pfam18938
Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a ...
 2201-2269 4.43e-08

Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a variety of bacterial cell surface proteins. These proteins share a conserved motif with the Rib domain (YPDXXD). The structure of the aRib domain has been solved from two proteins, the SrpA adhesin and the GspB adhesin. In these proteins this domain has been termed the unique domain due to its lack of similarity to any other known structures at the time. The aRib domain from SrpA has been shown to mediate a dimer interaction. This family has been added to the E-set clan based on its similarity to the Rib domain, although it does not contain the Ig fold.


Pssm-ID: 465921 [Multi-domain]  Cd Length: 71  Bit Score: 51.84  E-value: 4.43e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 2201 TLNPPTdKVPVDDTKHITDEDKGKVIDNVKKSNPDK-DITDAHVDDDG--TFHGKvDGQDVVIPGTETVVEK 2269
Cdd:pfam18938    2 TINIPE-KTEVKDPNKLTDEEKQEVKDAVKKANPDLpEGTKVEVDDDGtvTVTYP-DGSKDTIPAKDLVKEK 71
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1235-1313 4.59e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 52.23  E-value: 4.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1235 DAEKHNPQANILHATLNQDLSsndwAKKGILNADE-QDGATFRWRKGyvPDTSKEGQVWGIVVVSYPDSSINEVRVPVIV 1313
Cdd:pfam08428    1 DADKYTPKGKDITVEVGETPD----AEDGIKNKDDlPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVEVTVTV 74
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1946-2025 9.37e-08

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 51.07  E-value: 9.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1946 QSDDYNIETQPVNTDKdGNLPeNADSGIKNLGKLPEGTHASWgdgaQDIAKNLKPGeTKDVPATVVFPDGSKKEITIPVH 2025
Cdd:pfam08428    1 DADKYTPKGKDITVEV-GETP-DAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTVT 73
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 2135-2191 1.19e-07

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 51.07  E-value: 1.19e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1828715824 2135 NADSGIKNLGDLPEGTHAVWgqgaQTIVDGMKPGeTKDVPATIEFPDGSTKDVTIPV 2191
Cdd:pfam08428   21 DAEDGIKNKDDLPEGTKYTW----KTPPDTTTPG-DKTGTVVVTYPDGSTDEVEVTV 72
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 912-983 2.56e-07

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 50.26  E-value: 2.56e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824  912 DAYEAIKNHDDLPaDKAGYNWvvdENHPAVDTTKPGDQTGYVQVTYNDGSKsDLVPVTVHVI---ADNEKYTAIG 983
Cdd:TIGR02331   11 DASDSITNLVDLP-DGTTYVW---KTVNTPDTNTPGDKPAVVVVTYPDGTK-DTVPVTVHVTpprTDADKYDPAG 80
aRib pfam18938
Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a ...
 2273-2341 2.74e-07

Atypical Rib domain; This entry contains atypical Rib (aRib) domains. These are found in a variety of bacterial cell surface proteins. These proteins share a conserved motif with the Rib domain (YPDXXD). The structure of the aRib domain has been solved from two proteins, the SrpA adhesin and the GspB adhesin. In these proteins this domain has been termed the unique domain due to its lack of similarity to any other known structures at the time. The aRib domain from SrpA has been shown to mediate a dimer interaction. This family has been added to the E-set clan based on its similarity to the Rib domain, although it does not contain the Ig fold.


Pssm-ID: 465921 [Multi-domain]  Cd Length: 71  Bit Score: 49.91  E-value: 2.74e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 2273 SLNPPTdKVPVDDTKHITDEDKGKVIDNVKKSNPDK-DITDAHVDDDG--TFHGKvDGQDVVIPGIETVVEK 2341
Cdd:pfam18938    2 TINIPE-KTEVKDPNKLTDEEKQEVKDAVKKANPDLpEGTKVEVDDDGtvTVTYP-DGSKDTIPAKDLVKEK 71
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1679-1764 3.71e-07

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 49.87  E-value: 3.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1679 IKTLPGQTVNPEDGVINLhkpgennPQLPDGTKVTFDNQSDVDDFTkhgmPGsDKSFDATVTYPDGTTDKIKLPVHIT-- 1756
Cdd:TIGR02331    2 ETVEVGGTPDASDSITNL-------VDLPDGTTYVWKTVNTPDTNT----PG-DKPAVVVVTYPDGTKDTVPVTVHVTpp 69


                   ....*....
gi 1828715824 1757 -ADNEVNTP 1764
Cdd:TIGR02331   70 rTDADKYDP 78
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 823-897 6.42e-07

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 49.10  E-value: 6.42e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1828715824  823 DASQYITNKDEIanikPGTTDYEPTfksaAWKSVDTNT---KKGIITVTYADNTTTDLDVDLNVVDKITDADKFTPEG 897
Cdd:TIGR02331   11 DASDSITNLVDL----PDGTTYVWK----TVNTPDTNTpgdKPAVVVVTYPDGTKDTVPVTVHVTPPRTDADKYDPAG 80
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 118-634 2.17e-06

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 53.24  E-value: 2.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  118 TQDRTDSNDNATTNQVDTTQVSTTSLKAVQSSNQAANLLAESKVEDSTTANVSDFDSFNSALMNQNITTININSDFTSGN 197
Cdd:COG4625     23 GGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGTGGVGGGGGGGGG 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  198 YGTNVEHRRVVPRTLVINGNGHTVDLGSIGYFMNPGGNQAADWTVENGTFYSKSAVGPFALTGDHGTDKAWQATNGAVHR 277
Cdd:COG4625    103 GGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGG 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  278 MTYKDMTVYAGGGAYAANAEIDLEGTNNLNATASYQSKFSNGTVYTETGGNRSGVEGQWIIIKDNANVTVNTDHGQAIST 357
Cdd:COG4625    183 GGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGG 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  358 EYSDGNHRIEVGENATLNGNYLYTTYGTPYGGGKIPVLSNGANGGTVIFHKGSKSHFTMPNQNVTGFGGNGFSNYGT--- 434
Cdd:COG4625    263 GAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGsgg 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  435 GSVLYLGAANTTIEKGAEVTIDNPKEANNDNSIFIRSDGTQLNIFGNLIINDGARDYTIRADNRVSINVGQSIADDDYSN 514
Cdd:COG4625    343 AGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGG 422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  515 DNGKLIINRNGDFYLNNDGGALSMWGPITINVNSGAALEVYSTGINNVSGSGANPALMRVGGSSKLNVYKRGTFILSDSS 594
Cdd:COG4625    423 GGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGS 502

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1828715824  595 NGKVSL----VDDYNANGNFNFDNTAKVIFDISNNNNQNSRIFA 634
Cdd:COG4625    503 TLAVEVdaanSDRLVVTGTATLNGGTVVVLAGGYAPGTTYTILA 546
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 369-910 5.55e-06

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 52.09  E-value: 5.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  369 GENATLNGNYLYTTYGTPYGGGKIPVLSNGANGGTVIFHKGSKSHFTMPNQNVTGFGGNGFSNYGTGSVLYLGAANTTIE 448
Cdd:COG4625      1 GGGGGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  449 KGAEVTIDNPKEANNDNSIFIRSDGTQLNIFGNLIINDGARDYTIRADNRVSINVGQSIADDDYSNDNGKLIINRNGDFY 528
Cdd:COG4625     81 GGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  529 LNNDGGALSMWGPITINVNSGAALEVYSTGINNVSGSGANPALMRVGGSSKLNVYKRGTFILSDSSNGKVSLVDDYNANG 608
Cdd:COG4625    161 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGG 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  609 NFNFDNTAKVIFDISNNNNQNSRIFALNGTVYATHdkVRAMLTPSSNIADMGTFKTVQFNTSGQGGVTGDALHSEYQNQA 688
Cdd:COG4625    241 GGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGS--GGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  689 YNNIVAIRDAIRTGQLRYLEFSTRSVNNASITGEGHGFTDNGAQIKGSVVDESTNTGAVAVAYDKDNNKVGSGNVDDQGN 768
Cdd:COG4625    319 GGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGG 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  769 FTINLDKPLLNKEEVKVRIETPRGASGFVSTTAPLGPTAKSPITVAKDDNLAGQDASQYITNKDEIANIKPGTTDYEPTF 848
Cdd:COG4625    399 GGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTL 478

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824  849 KSAAWKSVDTNTKKGIiTVTYADNTTTDLDVDLNVVDKITDADKFTPEGGTIKVDNGHKLDG 910
Cdd:COG4625    479 TGNNTYTGTTTVNGGG-NYTQSAGSTLAVEVDAANSDRLVVTGTATLNGGTVVVLAGGYAPG 539
Gram_pos_anchor pfam00746
LPXTG cell wall anchor motif;
2382-2419 1.12e-05

LPXTG cell wall anchor motif;


Pssm-ID: 366278 [Multi-domain]  Cd Length: 43  Bit Score: 44.45  E-value: 1.12e-05
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1828715824 2382 KQNRLPQTGSE-TSGLSALGLAMLsLVGLGFLIKKRKED 2419
Cdd:pfam00746    5 KKKTLPKTGENsNIFLTAAGLLAL-LGGLLLLVKRRKKE 42
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1427-1493 1.93e-05

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 44.87  E-value: 1.93e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1828715824 1427 TPVAEKAVSNLDELKDVSSITWAT--TPDVSKVGNVPAIVVVTYKDGTSNAAPINIEV---KGLANDYKPEG 1493
Cdd:TIGR02331    9 TPDASDSITNLVDLPDGTTYVWKTvnTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVtppRTDADKYDPAG 80
YSIRK_signal pfam04650
YSIRK type signal peptide; Many surface proteins found in Streptococcus, Staphylococcus, and ...
 17-42 2.20e-05

YSIRK type signal peptide; Many surface proteins found in Streptococcus, Staphylococcus, and related lineages share apparently homologous signal sequences. A motif resembling [YF]SIRKxxxGxxS[VIA] appears at the start of the transmembrane domain. The GxxS motif appears perfectly conserved, suggesting a specific function and not just homology. There is a strong correlation between proteins carrying this region at the N-terminus and those carrying the Gram-positive anchor domain with the LPXTG sortase processing site at the C-terminus.


Pssm-ID: 428049 [Multi-domain]  Cd Length: 26  Bit Score: 43.14  E-value: 2.20e-05
                           10        20
                   ....*....|....*....|....*.
gi 1828715824   17 KEQQHFALRKLNVGLVSVLMGTTLFF 42
Cdd:pfam04650    1 EKKQRYSIRKLSVGVASVLIGTLLFL 26
RibLong pfam18957
Long Rib domain; This entry represents the Long Rib domain that is closely related to the ...
 1146-1229 2.46e-05

Long Rib domain; This entry represents the Long Rib domain that is closely related to the pfam08428 Rib domain but has a conserved insertion. These domains are found in bacterial cell surface proteins.


Pssm-ID: 436864 [Multi-domain]  Cd Length: 92  Bit Score: 45.00  E-value: 2.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1146 AEKYSPVPETISVPKGTDlsgrakdgiANADKDANGKEKLPDGTKYEWDGGVPNTSVTNNKYGH---------------- 1209
Cdd:pfam18957    1 ADEYEPSYEPVSVKAGET---------VTVAAPTFDKDTLPEGTTFTLGDDAPWWVTVDENTGEvtvtppadakpgdyev 71

                           90       100
                   ....*....|....*....|.
gi 1828715824 1210 -VKVTYPDGSSTVVEVPLNIT 1229
Cdd:pfam18957   72 pVTVTYPDGSTDTVTVTVTVT 92
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 122-487 1.10e-04

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 47.63  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  122 TDSNDNATTNQVDTTQVSTTSLKAVQSSNQAANLLAESKVEDSTTANVSDFDSFNSALMNQNITTININSDFTSGNYGTN 201
Cdd:COG3468     55 NGGGGGGGAGGGGGGAGSGGGLAGAGSGGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTG 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  202 VEHRRVVPRTLVINGNGHTVDL-GSIGYFMNPGGNQAADWTVENGTFYSKSAVGPFALTGDHGTDKAWQATNGAVHRMTY 280
Cdd:COG3468    135 SAGGGGGGGGGGTGVGGTGAAAaGGGTGSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGG 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  281 KDMTVYAGGGAYAANAEIDLEGTNNLNATASYQSKFSNGTVYTETGGNRSGVEG-------------QWIIIKDNANVTV 347
Cdd:COG3468    215 GGGGGGAGGATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAAGTGGGGGGTgtgsggggggganGGGSGGGGGASGT 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  348 NTDHGQAISTEYSDGNHRIEVGENATLNGNYLYTTYGTPYGGGKIPVLSNGANGGTVIFHKGSKSHFTMPNQNVTGFGGN 427
Cdd:COG3468    295 GGGGTASTGGGGGGGGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSG 374

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  428 GFSNYGTGSVLYLGAANTTIEKGAEVTIDNPKEANNDNSIFIRSDGTQLNIFGNLIINDG 487
Cdd:COG3468    375 GGGGAGGGGANTGSDGVGTGLTTGGTGNNGGGGVGGGGGGGLTLTGGTLTVNGNYTGNNG 434
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 2385-2417 1.25e-04

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 40.92  E-value: 1.25e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1828715824 2385 RLPQTGSE-TSGLSALGLAMLSLVGLGFLIKKRK 2417
Cdd:TIGR01167    1 KLPKTGESgNSLLLLLGLLLLGLGGLLLRKRKKK 34
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1260-1320 1.36e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 42.56  E-value: 1.36e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1828715824 1260 AKKGILNADE-QDGATFRWRKGYVPDTSKEGQVWGIVVVSYPDSSINEVRVPVIVQ---SDASKY 1320
Cdd:TIGR02331   12 ASDSITNLVDlPDGTTYVWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTpprTDADKY 76
Rib pfam08428
Rib domain; The region featured in this family is found repeated in a number of bacterial ...
 1587-1667 2.28e-04

Rib domain; The region featured in this family is found repeated in a number of bacterial surface proteins, such as Rib and alpha. These are expressed by group B streptococci, and Rib is thought to confer protective immunity.


Pssm-ID: 462474 [Multi-domain]  Cd Length: 76  Bit Score: 41.83  E-value: 2.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1587 IAKYKGNIPQASDGIANKDqatkegdkdfpslaDVLAPNGIQWKKNfePDLSKPGLTSGEAILTFKDGSTAEVTIPVLVQ 1666
Cdd:pfam08428   12 ITVEVGETPDAEDGIKNKD--------------DLPEGTKYTWKTP--PDTTTPGDKTGTVVVTYPDGSTDEVEVTVTVT 75


                   .
gi 1828715824 1667 T 1667
Cdd:pfam08428   76 D 76
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 17-203 2.39e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.44  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824   17 KEQQHFALRKLNVGLVSVLMGTTLFFvGQTSIAKADTLESTKTsvteiSSSSNSNQEKLEQAKAVSSQEQTTSTEENVDS 96
Cdd:NF033609     4 KKKEKHAIRKKSIGVASVLVGTLIGF-GLLSSKEADASENSVT-----QSDSASNESKSNDSSSVSAAPKTDDTNVSDTK 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824   97 ASSSQSKSENNSSSSAKSEVSTQdrtDSNDNATTNQVDTTQVSTTSLK-------AVQSSNQAANLLAESKVEDSTTANV 169
Cdd:NF033609    78 TSSNTNNGETSVAQNPAQQETTQ---SASTNATTEETPVTGEATTTATnqantpaTTQSSNTNAEELVNQTSNETTSNDT 154

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1828715824  170 SDFDSFNSALMNQNITTININSDFTSGNYGTNVE 203
Cdd:NF033609   155 NTVSSVNSPQNSTNAENVSTTQDTSTEATPSNNE 188
YSIRK_signal TIGR01168
Gram-positive signal peptide, YSIRK family; Many surface proteins found in Streptococcus, ...
 17-45 2.47e-04

Gram-positive signal peptide, YSIRK family; Many surface proteins found in Streptococcus, Staphylococcus, and related lineages share apparently homologous signal sequences. A motif resembling [YF]SIRKxxxGxxS[VIA] appears at the start of the transmembrane domain. The GxxS motif appears perfectly conserved, suggesting a specific function and not just homology. There is a strong correlation between proteins carrying this region at the N-terminus and those carrying the Gram-positive anchor domain with the LPXTG sortase processing site at the C-terminus.


Pssm-ID: 273479 [Multi-domain]  Cd Length: 39  Bit Score: 40.54  E-value: 2.47e-04
                           10        20
                   ....*....|....*....|....*....
gi 1828715824   17 KEQQHFALRKLNVGLVSVLMGtTLFFVGQ 45
Cdd:TIGR01168    6 EKQQKYSIRKLSVGVASVLVA-SLFFGGG 33
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1768-1856 3.41e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 41.40  E-value: 3.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1768 GIITPKDSVPDANKGIANLkkattkegktyPALPENTTVEWVNPGQMKTELENAKGGTTknydaVVIYPDKSTEIVSIPV 1847
Cdd:TIGR02331    1 GETVEVGGTPDASDSITNL-----------VDLPDGTTYVWKTVNTPDTNTPGDKPAVV-----VVTYPDGTKDTVPVTV 64

                           90
                   ....*....|..
gi 1828715824 1848 TV---ATDADTY 1856
Cdd:TIGR02331   65 HVtppRTDADKY 76
Big_6 pfam17936
Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial ...
 726-803 5.10e-04

Bacterial Ig domain; This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.


Pssm-ID: 465576 [Multi-domain]  Cd Length: 83  Bit Score: 41.07  E-value: 5.10e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1828715824  726 FTDNGAQIKGSvvdesTNTGAVAVAYDKDNNKVGSGNVDDQGNFTINLDKPLLNKEEVKVrieTPRGASGFVSTTAPL 803
Cdd:pfam17936   10 VSDDGTTLTGT-----GEAGATVTVKDADGNVLGTGTVDADGTFSVTLDPAQANGETLSV---TATDAAGNVSPAATI 79
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 1591-1676 6.97e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 40.63  E-value: 6.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1591 KGNIPQASDGIANKDqatkegdkDFPSLADVlapngiQWKKNFEPDLSKPGLTSGEAILTFKDGSTAEVTIPVLVQ---T 1667
Cdd:TIGR02331    6 VGGTPDASDSITNLV--------DLPDGTTY------VWKTVNTPDTNTPGDKPAVVVVTYPDGTKDTVPVTVHVTpprT 71


                   ....*....
gi 1828715824 1668 DADRNTPET 1676
Cdd:TIGR02331   72 DADKYDPAG 80
rib_alpha TIGR02331
Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 ...
 2124-2206 8.65e-04

Rib/alpha/Esp surface antigen repeat; Sequences in this family are tandem repeats of about 79 amino acids, present in up to 14 copies in a protein and highly identical, even at the DNA level, within each protein. Sequences with these repeats are found in the Rib and alpha surface antigens of group B Streptococcus, Esp of Enterococcus faecalis, and related proteins of Lactobacillus. The repeat lacks Cys residues. Most members of this protein family also have the cell wall anchor motif LPXTG shared by many staphyloccal and streptococcal surface antigens.


Pssm-ID: 131384 [Multi-domain]  Cd Length: 80  Bit Score: 40.24  E-value: 8.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 2124 VETDSHGQLPEnADSGIKNLGDLPEGTHAVWGQGAQtiVDGMKPGEtKDVPATIEFPDGSTKDVTIPVYKTSTRDQGTLN 2203
Cdd:TIGR02331    1 GETVEVGGTPD-ASDSITNLVDLPDGTTYVWKTVNT--PDTNTPGD-KPAVVVVTYPDGTKDTVPVTVHVTPPRTDADKY 76


                   ...
gi 1828715824 2204 PPT 2206
Cdd:TIGR02331   77 DPA 79
YPDG_rpt NF038186
YPDG domain; The YPDG domain may occur once in a protein, or up to 22 times in tandem repeats. ...
 1111-1142 1.23e-03

YPDG domain; The YPDG domain may occur once in a protein, or up to 22 times in tandem repeats. It is common in proteins of Gram-positive bacteria with C-terminal LPXTG sites for anchoring on the cell surface.


Pssm-ID: 439498 [Multi-domain]  Cd Length: 98  Bit Score: 40.43  E-value: 1.23e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1828715824 1111 APDTSKTGD-IPATVKVTYPDGSYNTVDVTVHV 1142
Cdd:NF038186    66 APEDAKPGDeVTVPVTVTYPDGSTDEVPATVTV 98
RibLong pfam18957
Long Rib domain; This entry represents the Long Rib domain that is closely related to the ...
 1001-1060 1.99e-03

Long Rib domain; This entry represents the Long Rib domain that is closely related to the pfam08428 Rib domain but has a conserved insertion. These domains are found in bacterial cell surface proteins.


Pssm-ID: 436864 [Multi-domain]  Cd Length: 92  Bit Score: 39.61  E-value: 1.99e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1828715824 1001 ANKDGEVSQDGKTYTKLPDGTKYEWVDGGIDTSTI-----------------GPKQAQVKVTYPDGTTQIVPVKANV 1060
Cdd:pfam18957   15 AGETVTVAAPTFDKDTLPEGTTFTLGDDAPWWVTVdentgevtvtppadakpGDYEVPVTVTYPDGSTDTVTVTVTV 91
Ig_like_BLP2 NF040520
Ig-like repeat protein Blp2; Blp2 (BAP-like protein 2), found broadly in the genus ...
 752-807 2.90e-03

Ig-like repeat protein Blp2; Blp2 (BAP-like protein 2), found broadly in the genus Acinetobacter, resembles the much larger biofilm-associated proteins Bap and Blp1 in N-terminal sequence and the presence of tandem Ig-like repeats.


Pssm-ID: 468522 [Multi-domain]  Cd Length: 729  Bit Score: 43.10  E-value: 2.90e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1828715824  752 DKDNNKVGSGNVDDQGNFTINLDKPLLNKEEVKVrieTPRGASGFVS----------TTAPLGPTA 807
Cdd:NF040520   197 DATGKVIATGQADASGNYTIKLDQPLVNGNKVNV---TAIDAAGNASkatvvtgtkdTIAPDAPQA 259
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 27-1181 5.03e-03

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 42.45  E-value: 5.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824   27 LNVGLVSVLMGTTLFFVGQTSIAKADTLESTKTSVTEISSSSNSNQEKLEQAKAVSSQEQTTSTEENVDSASSSQSKSEN 106
Cdd:COG3210    531 GTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGA 610

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  107 NSSSSAKSEVSTQDRTDSNDNATTNQVDTTQVSTTSLKAVQSSNQAANLLAESKVEDSTTANVSDFDSFNSALMNQNITT 186
Cdd:COG3210    611 TGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTT 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  187 ININSDFTSGNYGTNVEHRRVVPRTLVINGNGHTVDLGSIGYFMNPGGNQA---ADWTVENGTFYSKSAVGPFALTGDhG 263
Cdd:COG3210    691 LNAATGGTLNNAGNTLTISTGSITVTGQIGALANANGDTVTFGNLGTGATLtlnAGVTITSGNAGTLSIGLTANTTAS-G 769

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  264 TDKAWQATNGAVHRMTYKDMTVYAGGGAYAANAEIDLEGTNNLNATASYQS-KFSNGTVYTETGGNRSGVEGQWIIIKDN 342
Cdd:COG3210    770 TTLTLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSGGTiTINTATTGLTGTGDTTSGAGGSNTTDTT 849

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  343 ANVTVNTDHGQAISTEYSDGNHRIEVGENATLNGNYLYTTYGTPYGGGKIPVLSNGANGGTVIFHKGSKSHFTMPNQNVT 422
Cdd:COG3210    850 TGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGG 929

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  423 GFGGNGFSNYGTGSVLYLGAANTTIEKGAEVTIDNPKEANNDNSIFIRSDGTQLNIFGNLIINDGARDYTIRADNRVSIN 502
Cdd:COG3210    930 NAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTT 1009

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  503 VGQSIADDDYSNDNGKLIINRNGDFYLNNDGGALSMWGPITINVNSGAALEVYSTGINNVSGSGANPALMRVGGSSKLNV 582
Cdd:COG3210   1010 GGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAG 1089

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  583 YKRGTFILSDSSNGKVSLVDDYNANGNFNFDNTAKVIFDISNNNNQNSRIFALNGTVYATHDKVRAMLTPSSNIADMGTF 662
Cdd:COG3210   1090 TTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAV 1169

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  663 KTVQFNTSGQGGVTGDALHSEYQNQAYNNIVAIRDAIRTGQLRYLEFSTRSVNNASITGEGHGFTDNGAQIKGSVVDEST 742
Cdd:COG3210   1170 AAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGS 1249

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  743 NTGAVAVAYDKDNNKVGSGNVDDQGNFTINLDKPLLNKEEVKVRIETPRGASGFVSTTAPLGPTAKSPITVAKDDNLAGQ 822
Cdd:COG3210   1250 ASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTGNTAGANGATVGTGIGGTTATGTAVA 1329

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  823 DASQYITNKDEIANIKPGTTDYEPTFKSAA--WKSVDTNTKKGIITVTYADNTTTDLDVDLNVVDKITDADKFTPEGGTI 900
Cdd:COG3210   1330 AVNSGGVNAGGGTINTTAANTGLNGGNGATdsAAGAGSGGAAGSLAATAGAGTVLTGAGNNTGAEGTNAGRDGGVTTSGT 1409

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  901 KVDNGHKLDGNDAYEAIKNHDDLPADKAGYNWVVDENHPAVDTTKPGDQTGYVQVTYNDGSKSDLVPVTVHVIADNEKYT 980
Cdd:COG3210   1410 GVGNNGGVSGTTVAGTTGSSATTGTGGTGNTTGTSVAGAGGGNADASAINTGNASSLGAGGSTAGNAVGGAVIGGTTTGG 1489

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824  981 AIGKTQNLQKGQSANPQDFIANKDGEVSQDGKTYTKLPDGTKYEWVDGGIDTSTIGPKQAQVKVTYPDGTTQIVPVKANV 1060
Cdd:COG3210   1490 NGAGVAGATASNGGTSTGAGGTAGGTTAEVAKASLEGGEGTYGGSSVAEAGTGGGILGAVSGAGSEGGAAGGVTGSVGVG 1569

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1828715824 1061 YSDANLSTVVGKDINAGYKEDLTNRAIDAIDKDKSTNLPTDPSAYTWVNGAPDTSKTGDIPATVKVTYPDGSYNTVDVTV 1140
Cdd:COG3210   1570 GTDGAGGDTGGADDTGAQAPTAGNTATLTLSLAEGTNAEYGGTTNVTSGTAGNAGATGANSNTVVTTNGGEGVLALVAGG 1649

                         1130      1140      1150      1160
                   ....*....|....*....|....*....|....*....|.
gi 1828715824 1141 HVTSDAEKYSPVPETISVPKGTDLSGRAKDGIANADKDANG 1181
Cdd:COG3210   1650 NTTNGTTLSGAVNGAGNGWAVDLTDATLAGLGGATTAAAGN 1690
RibLong pfam18957
Long Rib domain; This entry represents the Long Rib domain that is closely related to the ...
 1111-1143 7.51e-03

Long Rib domain; This entry represents the Long Rib domain that is closely related to the pfam08428 Rib domain but has a conserved insertion. These domains are found in bacterial cell surface proteins.


Pssm-ID: 436864 [Multi-domain]  Cd Length: 92  Bit Score: 37.68  E-value: 7.51e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1828715824 1111 APDTSKTGDIPATVKVTYPDGSYNTVDVTVHVT 1143
Cdd:pfam18957   60 PPADAKPGDYEVPVTVTYPDGSTDTVTVTVTVT 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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