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Conserved domains on  [gi|1786101592|ref|WP_157272399|]
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IS3 family transposase [Azohydromonas aeria]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 super family cl41295
IS3 family transposase;
12-377 7.11e-162

IS3 family transposase;


The actual alignment was detected with superfamily member NF033516:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 458.95  E-value: 7.11e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  12 EFKEQAVKRAQEVGVGVA--ARELGLVAQTLRNWVKAAGAGQLS---GAGAKPVTAEQMEISRLRAENARLKMHVDLFKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAevARELGISPSTLYRWRKKYRGGGEAadaGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  87 SDGVLceRCAVKYAWIDAQRADYPLPDLCEALSVSVSGYRAWRRGGsPDTKRLSTAQAVALIKAIHAEFKGAYGSRRMHR 166
Cdd:NF033516   81 ARKLL--RPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRP-PSRRAPDDAELRARIREIFEESRGRYGYRRITA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 167 ELQGRGHRIGLERVERLMREHGIRARHKRRYKA-TTDSSHALPVAENLLARNFTPEAPNRVWTGDITYIATDEGWLYLAV 245
Cdd:NF033516  158 LLRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 246 VLDLFNREVVGWSLKPRMTADIVTDALTMAWFRSKPTPGVMFHSDRGSQYASHAMRCKLNEFGMTASMSRKGNCWDNAPT 325
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1786101592 326 ESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEF 377
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEF 368
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
12-377 7.11e-162

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 458.95  E-value: 7.11e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  12 EFKEQAVKRAQEVGVGVA--ARELGLVAQTLRNWVKAAGAGQLS---GAGAKPVTAEQMEISRLRAENARLKMHVDLFKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAevARELGISPSTLYRWRKKYRGGGEAadaGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  87 SDGVLceRCAVKYAWIDAQRADYPLPDLCEALSVSVSGYRAWRRGGsPDTKRLSTAQAVALIKAIHAEFKGAYGSRRMHR 166
Cdd:NF033516   81 ARKLL--RPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRP-PSRRAPDDAELRARIREIFEESRGRYGYRRITA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 167 ELQGRGHRIGLERVERLMREHGIRARHKRRYKA-TTDSSHALPVAENLLARNFTPEAPNRVWTGDITYIATDEGWLYLAV 245
Cdd:NF033516  158 LLRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 246 VLDLFNREVVGWSLKPRMTADIVTDALTMAWFRSKPTPGVMFHSDRGSQYASHAMRCKLNEFGMTASMSRKGNCWDNAPT 325
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1786101592 326 ESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEF 377
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEF 368
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
62-385 1.03e-106

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 316.32  E-value: 1.03e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  62 AEQMEISRLRAENARLKMHVDLFKKSDGVLCERCAVKYAWIDAQRADYPLPDLCEALSVSVSgYRAWRRggspdtkrlst 141
Cdd:COG2801     3 AEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRS-YRADED----------- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 142 AQAVALIKAIHAEFKgAYGSRRMHRELQGRGHRIGLERVERLMREHGIRARHKRRYKATTDSSHALPVAENLLarnFTPE 221
Cdd:COG2801    71 AELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FTAT 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 222 APNRVWTGDITYIATDEGWLYLAVVLDLFNREVVGWSLKPRMTADIVTDALTMAWFRSKPTPGVMFHSDRGSQYASHAMR 301
Cdd:COG2801   147 APNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQ 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 302 CKLNEFGMTASMSRKGNCWDNAPTESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEFLQSW 381
Cdd:COG2801   227 ELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQL 305


                  ....
gi 1786101592 382 ISKQ 385
Cdd:COG2801   306 AAAA 309
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 118-376 3.54e-77

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 239.77  E-value: 3.54e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 118 LSVSVSGYRAWRRGGSPDTKRLSTAQAVAL----IKAIHAEFKGAYGSRRMHRELQGRGHRIGLERVERLMREHGIRA-- 191
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHHPDKRRARAQHDDWlkseILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGvl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 192 RHKRRYKATTDSSHALPvaeNLLARNFTPEAPNRVWTGDITYIATDEGWLYLAVVLDLFNREVVGWSLKPRMTADIVTDA 271
Cdd:PHA02517   81 RGKKVRTTISRKAVAAP---DRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 272 LTMAWFRSKPTPGVMFHSDRGSQYASHAMRCKLNEFGMTASMSRKGNCWDNAPTESFFNSLKNERVHGARYATRQQASAD 351
Cdd:PHA02517  158 LEQALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELA 237

                         250       260
                  ....*....|....*....|....*
gi 1786101592 352 VFQYIeGFYNRRRRHSTLGYCSPQE 376
Cdd:PHA02517  238 TLEWV-AWYNNRRLHERLGYTPPAE 261
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 223-319 6.83e-28

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 105.47  E-value: 6.83e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 223 PNRVWTGDITYIA--TDEGWLYLAVVLDLFNREVVGWSLKPRMTADIVTDALTMAwFRSKPTPGVMFHSDRGSQYASHAM 300
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERA-IAFRGGVPLIIHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1786101592 301 RCKLNEFGMTASMSRKGNC 319
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 98-378 4.88e-16

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 77.63  E-value: 4.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  98 KYAWIDAQRAD-YPLPDLCEALSVSVSGYRAWR-------------RGGSPDTKRLSTAQAV-ALIKAIHAEFKgaYGSR 162
Cdd:NF033577    2 RLELVRLVLEDgWSVREAARRFGISRKTVYKWLkryraggeeglidRSRRPHRSPRRTSPETeARILALRRELR--LGPR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 163 RMHRELQGRGHRIGLERVERLMREHGI-RARHKRRYKATTdsshalpvaenllaRNFTPEAPNRVWTGDITYIAT--DEG 239
Cdd:NF033577   80 RIAYELERQGPGVSRSTVHRILRRHGLsRLRALDRKTGKV--------------KRYERAHPGELWHIDIKKLGRipDVG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 240 WLYLAVVLDLFNREVVGwSLKPRMTADIVTDALTMAwFRSKPTPGVMFHSDRGSQYASHAMRCK--LNEFGMTASMSRKG 317
Cdd:NF033577  146 RLYLHTAIDDHSRFAYA-ELYPDETAETAADFLRRA-FAEHGIPIRRVLTDNGSEFRSRAHGFElaLAELGIEHRRTRPY 223

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1786101592 318 NCWDNAPTESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEFL 378
Cdd:NF033577  224 HPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPAERF 283
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
12-377 7.11e-162

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 458.95  E-value: 7.11e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  12 EFKEQAVKRAQEVGVGVA--ARELGLVAQTLRNWVKAAGAGQLS---GAGAKPVTAEQMEISRLRAENARLKMHVDLFKK 86
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAevARELGISPSTLYRWRKKYRGGGEAadaGRLKELLTPEEEENRRLKRELAELRLENEILKK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  87 SDGVLceRCAVKYAWIDAQRADYPLPDLCEALSVSVSGYRAWRRGGsPDTKRLSTAQAVALIKAIHAEFKGAYGSRRMHR 166
Cdd:NF033516   81 ARKLL--RPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRP-PSRRAPDDAELRARIREIFEESRGRYGYRRITA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 167 ELQGRGHRIGLERVERLMREHGIRARHKRRYKA-TTDSSHALPVAENLLARNFTPEAPNRVWTGDITYIATDEGWLYLAV 245
Cdd:NF033516  158 LLRREGIRVNHKRVYRLMRELGLLARRRRKRRPyTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAV 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 246 VLDLFNREVVGWSLKPRMTADIVTDALTMAWFRSKPTPGVMFHSDRGSQYASHAMRCKLNEFGMTASMSRKGNCWDNAPT 325
Cdd:NF033516  238 VLDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVA 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1786101592 326 ESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEF 377
Cdd:NF033516  318 ESFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEF 368
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
62-385 1.03e-106

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 316.32  E-value: 1.03e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  62 AEQMEISRLRAENARLKMHVDLFKKSDGVLCERCAVKYAWIDAQRADYPLPDLCEALSVSVSgYRAWRRggspdtkrlst 141
Cdd:COG2801     3 AEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRS-YRADED----------- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 142 AQAVALIKAIHAEFKgAYGSRRMHRELQGRGHRIGLERVERLMREHGIRARHKRRYKATTDSSHALPVAENLLarnFTPE 221
Cdd:COG2801    71 AELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FTAT 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 222 APNRVWTGDITYIATDEGWLYLAVVLDLFNREVVGWSLKPRMTADIVTDALTMAWFRSKPTPGVMFHSDRGSQYASHAMR 301
Cdd:COG2801   147 APNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQ 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 302 CKLNEFGMTASMSRKGNCWDNAPTESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEFLQSW 381
Cdd:COG2801   227 ELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQL 305


                  ....
gi 1786101592 382 ISKQ 385
Cdd:COG2801   306 AAAA 309
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 118-376 3.54e-77

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 239.77  E-value: 3.54e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 118 LSVSVSGYRAWRRGGSPDTKRLSTAQAVAL----IKAIHAEFKGAYGSRRMHRELQGRGHRIGLERVERLMREHGIRA-- 191
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHHPDKRRARAQHDDWlkseILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGvl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 192 RHKRRYKATTDSSHALPvaeNLLARNFTPEAPNRVWTGDITYIATDEGWLYLAVVLDLFNREVVGWSLKPRMTADIVTDA 271
Cdd:PHA02517   81 RGKKVRTTISRKAVAAP---DRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 272 LTMAWFRSKPTPGVMFHSDRGSQYASHAMRCKLNEFGMTASMSRKGNCWDNAPTESFFNSLKNERVHGARYATRQQASAD 351
Cdd:PHA02517  158 LEQALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELA 237

                         250       260
                  ....*....|....*....|....*
gi 1786101592 352 VFQYIeGFYNRRRRHSTLGYCSPQE 376
Cdd:PHA02517  238 TLEWV-AWYNNRRLHERLGYTPPAE 261
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 223-319 6.83e-28

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 105.47  E-value: 6.83e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 223 PNRVWTGDITYIA--TDEGWLYLAVVLDLFNREVVGWSLKPRMTADIVTDALTMAwFRSKPTPGVMFHSDRGSQYASHAM 300
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERA-IAFRGGVPLIIHSDNGSEYTSKAF 79

                          90
                  ....*....|....*....
gi 1786101592 301 RCKLNEFGMTASMSRKGNC 319
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-91 1.40e-19

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 82.66  E-value: 1.40e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592   1 MKRiPKQEYTAEFKEQAVKRAQEVGVGVA--ARELGLVAQTLRNWVKAAGAGQLSG-AGAKPVTAEQMEISRLRAENARL 77
Cdd:COG2963     1 MSK-KRRRYSPEFKAEAVRLVLEGGASVAevARELGISPSTLYRWVRQYREGGLGGfPGDGRTTPEQAEIRRLRKELRRL 79

                          90
                  ....*....|....
gi 1786101592  78 KMHVDLFKKSDGVL 91
Cdd:COG2963    80 EMENDILKKAAALL 93
transpos_IS481 NF033577
IS481 family transposase; null
 98-378 4.88e-16

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 77.63  E-value: 4.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592  98 KYAWIDAQRAD-YPLPDLCEALSVSVSGYRAWR-------------RGGSPDTKRLSTAQAV-ALIKAIHAEFKgaYGSR 162
Cdd:NF033577    2 RLELVRLVLEDgWSVREAARRFGISRKTVYKWLkryraggeeglidRSRRPHRSPRRTSPETeARILALRRELR--LGPR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 163 RMHRELQGRGHRIGLERVERLMREHGI-RARHKRRYKATTdsshalpvaenllaRNFTPEAPNRVWTGDITYIAT--DEG 239
Cdd:NF033577   80 RIAYELERQGPGVSRSTVHRILRRHGLsRLRALDRKTGKV--------------KRYERAHPGELWHIDIKKLGRipDVG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 240 WLYLAVVLDLFNREVVGwSLKPRMTADIVTDALTMAwFRSKPTPGVMFHSDRGSQYASHAMRCK--LNEFGMTASMSRKG 317
Cdd:NF033577  146 RLYLHTAIDDHSRFAYA-ELYPDETAETAADFLRRA-FAEHGIPIRRVLTDNGSEFRSRAHGFElaLAELGIEHRRTRPY 223

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1786101592 318 NCWDNAPTESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEFL 378
Cdd:NF033577  224 HPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTPAERF 283
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 143-197 1.65e-15

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 70.29  E-value: 1.65e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1786101592 143 QAVALIKAIHAEFKGAYGSRRMHRELQGRGH-RIGLERVERLMREHGIRARHKRRY 197
Cdd:pfam13276   5 ELLEAIREIFEESRGTYGYRRITAELRREGGiRVNRKRVARLMRELGLRARRRRKR 60
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 1-75 1.58e-13

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 65.07  E-value: 1.58e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1786101592   1 MKRipKQEYTAEFKEQAVKRAQEVGVGVA--ARELGLVAQTLRNWVKAAGAGQLSGAGAKPVTAEQMEISRLRAENA 75
Cdd:pfam01527   1 MKK--RRRFSEEFKLRAVKEVLEPGRTVKevARRHGVSPNTLYQWRRQYEGGMGASPARPRLTALEEENRRLKRELA 75
rve_3 pfam13683
Integrase core domain;
308-374 2.92e-09

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 52.99  E-value: 2.92e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1786101592 308 GMTASMSRKGNCWDNAPTESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSP 374
Cdd:pfam13683   2 GIEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWRE-DYNTERPHSSLGYRTP 67
rve_2 pfam13333
Integrase core domain;
326-377 1.19e-08

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 50.72  E-value: 1.19e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1786101592 326 ESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHstlgYCSPQEF 377
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIE-WYNNKRLK----GLSPVQY 47
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
 159-379 6.56e-06

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 47.40  E-value: 6.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 159 YGSRRMHRELQGRGHRIGL-----ERVERLMREHGIRARHKRrykattdsshALPVAENLLARNFTPEAPNRVWTGDITY 233
Cdd:PRK09409   66 YGYRRVWALLRRQAELDGMpainaKRVYRIMRQNALLLERKP----------AVPPSKRAHTGRVAVKESNQRWCSDGFE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 234 IATDEG-WLYLAVVLDLFNREVVGWSL-----KPRMTADIVTDALTMAWFRSKPTPGVMFHSDRGSQYASHAMRCKLNEF 307
Cdd:PRK09409  136 FCCDNGeRLRVTFALDCCDREALHWAVttggfNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARML 215

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1786101592 308 GMTASMSRKGNCWDNAPTESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEFLQ 379
Cdd:PRK09409  216 GLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFE-HYNEWHPHSALGYRSPREYLR 286
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
 159-379 1.04e-05

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 46.65  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 159 YGSRRMHRELQGRGHRIGL-----ERVERLMREHGIRARHKRrykattdsshALPVAENLLARNFTPEAPNRVWTGDITY 233
Cdd:PRK14702   27 YGYRRVWALLRRQAELDGMpainaKRVYRLMRQNALLLERKP----------AVPPSKRAHTGRVAVKESNQRWCSDGFE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786101592 234 IATDEG-WLYLAVVLDLFNREVVGWS-----LKPRMTADIVTDALTMAWFRSKPTPGVMFHSDRGSQYASHAMRCKLNEF 307
Cdd:PRK14702   97 FCCDNGeRLRVTFALDCCDREALHWAvttggFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARML 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1786101592 308 GMTASMSRKGNCWDNAPTESFFNSLKNERVHGARYATRQQASADVFQYIEgFYNRRRRHSTLGYCSPQEFLQ 379
Cdd:PRK14702  177 GLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFE-HYNEWHPHSALGYRSPREYLR 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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