|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
48-400 |
3.88e-120 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 353.47 E-value: 3.88e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 48 IMFVLPALG-AGGSEHVVTFLANRLVACGLRITIVSFEDGSAPPYYRCDPEVSITYLGVPigRRGKVKGLNAFAARVAGL 126
Cdd:cd03820 2 IAIVIPSISnAGGAERVAINLANHLAKKGYDVTIISLDSAEKPPFYELDDNIKIKNLGDR--KYSHFKLLLKYFKKVRRL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 127 RSQMDAVRPDLVISFLTRTNVIsvLAARNLRIPVIVSERNNPQRQRPPLPWRVMRRLAYARAYGLVTMTQGALQFFPRSM 206
Cdd:cd03820 80 RKYLKNNKPDVVISFRTSLLTF--LALIGLKSKLIVWEHNNYEAYNKGLRRLLLRRLLYKRADKIVVLTEADKLKKYKQP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 207 RQRGWVIPNMADWQHFKPRFTNTIRVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIA 286
Cdd:cd03820 158 NSNVVVIPNPLSFPSEEPSTNLKSKRILAVGRLTYQKGFDLLIEAWALIAKKHPDWKLRIYGDGPEREELEKLIDKLGLE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 287 DRVEMPGVSSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPFGPAEMISDKVDGLLAPDGDVPALAEALS 366
Cdd:cd03820 238 DRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPTGPSEIIEDGENGLLVPNGDVDALAEALL 317
|
330 340 350
....*....|....*....|....*....|....
gi 1784594042 367 KVMGDAGLRDRLGANAIRKARLFEPERIGGLWEA 400
Cdd:cd03820 318 RLMEDEELRKKMGKNARKNAERFSIEKIIKQWEE 351
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
48-390 |
1.01e-77 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 244.96 E-value: 1.01e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 48 IMFVLPALGAGGSEHVVTFLANRLVACGLRITIVSFEDGSappYYRCDPEVSITYLGVPIGRRGKVKGLNAfaARVAGLR 127
Cdd:cd03811 2 ILFVIPSLSGGGAERVLLNLANALDKRGYDVTLVLLRDEG---DLDKQLNGDVKLIRLLIRVLKLIKLGLL--KAILKLK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 128 SQMDAVRPDLVISFLTRTNVISVLAArNLRIPVIVSERNNPQRQRPPLPWRVMRRLAYARAYGLVTMTQGA----LQFFP 203
Cdd:cd03811 77 RILKRAKPDVVISFLGFATYIVAKLA-AARSKVIAWIHSSLSKLYYLKKKLLLKLKLYKKADKIVCVSKGIkedlIRLGP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 204 RSmRQRGWVIPNMADWQHFKPR--------FTNTIRVLTaVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDA 275
Cdd:cd03811 156 SP-PEKIEVIYNPIDIDRIRALakepilnePEDGPVILA-VGRLDPQKGHDLLIEAFAKLRKKYPDVKLVILGDGPLREE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 276 LQALAASLGIADRVEMPGVSSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPD 355
Cdd:cd03811 234 LEKLAKELGLAERVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCP-GPREILDDGENGLLVPD 312
|
330 340 350
....*....|....*....|....*....|....*...
gi 1784594042 356 GDVPALAE---ALSKVMGDAGLRDRLGANAIRKARLFE 390
Cdd:cd03811 313 GDAAALAGilaALLQKKLDAALRERLAKAQEAVFREYT 350
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
48-403 |
2.58e-56 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 189.67 E-value: 2.58e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 48 IMFVLPAL--GAGGSEHVVTFLANRLVACGLRITIVSFEDGSAPPYYRCDPEVSITYLGVPIGRRgkvkglnaFAARVAG 125
Cdd:cd03801 2 ILLLSPELppPVGGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLR--------ARRLLRE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 126 LRSQMDAVRPDLVISFLTRTNVISVLAARNLRIPVIVSERNNPQRQRPPLPWRVMRRLAYARAYG-----LVTMTQGALQ 200
Cdd:cd03801 74 LRPLLRLRKFDVVHAHGLLAALLAALLALLLGAPLVVTLHGAEPGRLLLLLAAERRLLARAEALLrradaVIAVSEALRD 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 201 FF---PRSMRQRGWVIPNMADWQHFKPRFTNTI------RVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGK-G 270
Cdd:cd03801 154 ELralGGIPPEKIVVIPNGVDLERFSPPLRRKLgippdrPVLLFVGRLSPRKGVDLLLEALAKLLRRGPDVRLVIVGGdG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 271 PDRDALQALaaSLGIADRVEMPGVSSQP--GSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKV 348
Cdd:cd03801 234 PLRAELEEL--ELGLGDRVRFLGFVPDEelPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVG-GLPEVVEDGE 310
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1784594042 349 DGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRK-ARLFEPERIGGLWEAMIF 403
Cdd:cd03801 311 GGLVVPPDDVEALADALLRLLADPELRARLGRAARERvAERFSWERVAERLLDLYR 366
|
|
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
100-394 |
3.68e-47 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 165.46 E-value: 3.68e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 100 ITYLGVPIGRRGK--VKGLNAFAArvagLRSQMDAVRPDLVISFLTRTNVISVLAARNLRIPVIVS--------ERNNPQ 169
Cdd:cd03808 49 VKVIDIPILRRGInpLKDLKALFK----LYKLLKKEKPDIVHCHTPKPGILGRLAARLAGVPKVIYtvhglgfvFTEGKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 170 RQrppLPWRVMRRLAYARAYGLVTMTQG----ALQFFPRSMRQRGWVIPNMADWQHFKPRFTNTIR---VLTAVGRLTDQ 242
Cdd:cd03808 125 LR---LLYLLLEKLALLFTDKVIFVNEDdrdlAIKKGIIKKKKTVLIPGSGVDLDRFQYSPESLPSekvVFLFVARLLKD 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 243 KGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQPGSWIVDADAFVLSSRYEGWGLVLG 322
Cdd:cd03808 202 KGIDELIEAAKILKKKGPNVRFLLVGDGELENPSEILIEKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLL 281
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1784594042 323 EAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKA-RLFEPERI 394
Cdd:cd03808 282 EAMAAGRPVITTDVP-GCRELVIDGVNGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVeEKFDEEKV 353
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
47-382 |
2.09e-43 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 155.55 E-value: 2.09e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 47 TIMFVLPALGAGGSEHVVTFLANRLVACGLRITIVSF-EDGSAPPYYRcDPEVSITYLGVPIGRRgkvkglnafAARVAG 125
Cdd:cd03807 1 KVAHVITGLNVGGAETMLLRLLEHMDKSRFEHVVISLtGDGVLGEELL-AAGVPVVCLGLSSGKD---------PGVLLR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 126 LRSQMDAVRPDLVISFLTRTNVISVLAARNLRI-PVIVSERNNPQRQRPPLPWRVMRRLAYARAYGLVTMTQGALQFF-- 202
Cdd:cd03807 71 LAKLIRKRNPDVVHTWMYHADLIGGLAAKLAGGvKVIWSVRSSNIPQRLTRLVRKLCLLLSKFSPATVANSSAVAEFHqe 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 203 ----PRSMRqrgwVIPNMADWQHFKPRFTNTIR------------VLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRV 266
Cdd:cd03807 151 qgyaKNKIV----VIYNGIDLFKLSPDDASRARarrrlglaedrrVIGIVGRLHPVKDHSDLLRAAALLVETHPDLRLLL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 267 WGKGPDRDALQALAASLGIADRVEMPGVSSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCpfGPAEMISD 346
Cdd:cd03807 227 VGRGPERPNLERLLLELGLEDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDV--GGAAELVD 304
|
330 340 350
....*....|....*....|....*....|....*.
gi 1784594042 347 KVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANA 382
Cdd:cd03807 305 DGTGFLVPAGDPQALADAIRALLEDPEKRARLGRAA 340
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
231-385 |
6.14e-41 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 142.80 E-value: 6.14e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 231 RVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQPGSWIV--DADAF 308
Cdd:pfam00534 3 KIILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELlkIADVF 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1784594042 309 VLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRK 385
Cdd:pfam00534 83 VLPSRYEGFGIVLLEAMACGLPVIASDVG-GPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARKR 158
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
53-386 |
6.71e-40 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 146.37 E-value: 6.71e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 53 PALGAGGSEHVVTFLAnRLVACGLRITIVSFEDG-------SAPPYYRCDPEVSITYLGVPIGRRGKVKGLNAfaARVAG 125
Cdd:cd03798 10 NANSPGRGIFVRRQVR-ALSRRGVDVEVLAPAPWgpaaarlLRKLLGEAVPPRDGRRLLPLKPRLRLLAPLRA--PSLAK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 126 LRSQMDAVRPDLVI-SFLTRTNVISVLAARNLRIPVIVSERNNPQRQRPPLPW-RVMRRLAYARAYGLVT----MTQGAL 199
Cdd:cd03798 87 LLKRRRRGPPDLIHaHFAYPAGFAAALLARLYGVPYVVTEHGSDINVFPPRSLlRKLLRWALRRAARVIAvskaLAEELV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 200 QFFPRsmRQRGWVIPNMADWQHFKPRFTNTI-----RVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRD 274
Cdd:cd03798 167 ALGVP--RDRVDVIPNGVDPARFQPEDRGLGlpldaFVILFVGRLIPRKGIDLLLEAFARLAKARPDVVLLIVGDGPLRE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 275 ALQALAASLGIADRVEMPGV--SSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLL 352
Cdd:cd03798 245 ALRALAEDLGLGDRVTFTGRlpHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVG-GIPEVVGDPETGLL 323
|
330 340 350
....*....|....*....|....*....|....
gi 1784594042 353 APDGDVPALAEALSKVMgDAGLRDRLGANAIRKA 386
Cdd:cd03798 324 VPPGDADALAAALRRAL-AEPYLRELGEAARARV 356
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
231-371 |
7.07e-39 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 136.49 E-value: 7.07e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 231 RVLTAVGRLTD-QKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRdALQALAAslGIADRVEMPGVSSQPGSWIVDADAFV 309
Cdd:pfam13692 2 PVILFVGRLHPnVKGVDYLLEAVPLLRKRDNDVRLVIVGDGPEE-ELEELAA--GLEDRVIFTGFVEDLAELLAAADVFV 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1784594042 310 LSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMIsDKVDGLLAPDGDVPALAEALSKVMGD 371
Cdd:pfam13692 79 LPSLYEGFGLKLLEAMAAGLPVVATDVG-GIPELV-DGENGLLVPPGDPEALAEAILRLLED 138
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
48-390 |
2.34e-32 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 125.16 E-value: 2.34e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 48 IMFVLPALGAGGSEHVVTFLANRLVACGLRITIVSfEDGSAPPyyrcdpEVSITYLGVPIGRRGKVKGLNAFAARVAGLR 127
Cdd:cd03819 1 ILMLTPALEIGGAETYILDLARALAERGHRVLVVT-AGGPLLP------RLRQIGIGLPGLKVPLLRALLGNVRLARLIR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 128 SQmdavRPDLVISFLTRTNVISVLAARNLRIPVIVSERNNPQRQRPPLPWRVMRRLAYARAYGLVTMTQ----GALQFFP 203
Cdd:cd03819 74 RE----RIDLIHAHSRAPAWLGWLASRLTGVPLVTTVHGSYLATYHPKDFALAVRARGDRVIAVSELVRdhliEALGVDP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 204 RSMRqrgwVIPNMADWQHFKP----------RFTNTIRVLTAVGRLTDQKGFDLLLQAFAKVaDRHLDWKLRVWGKGPDR 273
Cdd:cd03819 150 ERIR----VIPNGVDTDRFPPeaeaeeraqlGLPEGKPVVGYVGRLSPEKGWLLLVDAAAEL-KDEPDFRLLVAGDGPER 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 274 DALQALAASLGIADRVEMPGVSSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLA 353
Cdd:cd03819 225 DEIRRLVERLGLRDRVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVG-GAREIVVHGRTGLLV 303
|
330 340 350
....*....|....*....|....*....|....*..
gi 1784594042 354 PDGDVPALAEALSKVMGDAGLRDRLGANAIRKARLFE 390
Cdd:cd03819 304 PPGDAEALADAIRAAKLLPEAREKLQAAAALTEAVRE 340
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
48-403 |
3.06e-29 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 117.16 E-value: 3.06e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 48 IMFVLPALGAGGSEHVVTFLANRLVACGLRITIVsfedgsappYYRCDPEVSitylgvPIGRRGKVKGLN------AFAA 121
Cdd:cd04951 2 ILYVITGLGLGGAEKQTVLLADQMFIRGHDVNIV---------YLTGEVEVK------PLNNNIIIYNLGmdknprSLLK 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 122 RVAGLRSQMDAVRPDLVISFLTRTNVISVLAARNLRIP-VIVSERNNPQRQRpplpwrvMRRLAYARAYGLVTMT----Q 196
Cdd:cd04951 67 ALLKLKKIISAFKPDVVHSHMFHANIFARFLRMLYPIPlLICTAHNKNEGGR-------IRMFIYRLTDFLCDITtnvsR 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 197 GALQFFPRSM---RQRGWVIPNMADWQHFKprFTNTIR--------------VLTAVGRLTDQKGFDLLLQAFAKVADRH 259
Cdd:cd04951 140 EALDEFIAKKafsKNKSVPVYNGIDLNKFK--KDINVRlkirnklnlkndefVILNVGRLTEAKDYPNLLLAISELILSK 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 260 LDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfG 339
Cdd:cd04951 218 NDFKLLIAGDGPLRNELERLICNLNLVDRVILLGQISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDAG-G 296
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1784594042 340 PAEMISDKVDglLAPDGDVPALAEALSKVMGDA-GLRDRLGANAIRKARLFEPERIGGLWEAMIF 403
Cdd:cd04951 297 VAEVVGDHNY--VVPVSDPQLLAEKIKEIFDMSdEERDILGNKNEYIAKNFSINTIVNEWERLYS 359
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
57-387 |
8.49e-28 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 113.49 E-value: 8.49e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 57 AGGSEHVVTFLANRLVACGLRITIVSFEDGSA-PPYYRCDPEVSItyLGVPIG-RRGKVKG-----LNAFAARVAGLRSQ 129
Cdd:cd03800 20 TGGQNVYVLELARALAELGYQVDIFTRRISPAdPEVVEIAPGARV--IRVPAGpPEYLPKEelwpyLEEFADGLLRFIAR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 130 MDaVRPDLVISFLTRTNVISVLAARNLRIPVIVS----ERNNPQRQRPPLPWRVMRRL-----AYARAYGLVTMTQGALQ 200
Cdd:cd03800 98 EG-GRYDLIHSHYWDSGLVGALLARRLGVPLVHTfhslGRVKYRHLGAQDTYHPSLRItaeeqILEAADRVIASTPQEAD 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 201 FFPRSM---RQRGWVIPNMADWQHFKP---RFTNTIRVLT--------AVGRLTDQKGFDLLLQAFAKVADRHLDWKLRV 266
Cdd:cd03800 177 ELISLYgadPSRINVVPPGVDLERFFPvdrAEARRARLLLppdkpvvlALGRLDPRKGIDTLVRAFAQLPELRELANLVL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 267 WGkGPDRD-------ALQALAASLGIADRVEMPGVSSQP--GSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSfDCP 337
Cdd:cd03800 257 VG-GPSDDplsmdreELAELAEELGLIDRVRFPGRVSRDdlPELYRAADVFVVPSLYEPFGLTAIEAMACGTPVVA-TAV 334
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1784594042 338 FGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKAR 387
Cdd:cd03800 335 GGLQDIVRDGRTGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERAR 384
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
57-400 |
1.27e-27 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 112.85 E-value: 1.27e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 57 AGGSEHVVTFLANRLVACGLRITIVSFEDG----SAPPYYRCDPEVSiTYLGVPIGRRGKVKGLNAFAARVAgLRSQmdA 132
Cdd:cd03821 13 AGGPVKVVLRLAAALAALGHEVTIVSTGDGyeslVVEENGRYIPPQD-GFASIPLLRQGAGRTDFSPGLPNW-LRRN--L 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 133 VRPDLVISFLTRTNVISVLA--ARNLRIPVIVSernnPQ-------RQRPPLPWRVMRRLAYAR-----AYGLVTMTQGA 198
Cdd:cd03821 89 REYDVVHIHGVWTYTSLAACklARRRGIPYVVS----PHgmldpwaLQQKHWKKRIALHLIERRnlnnaALVHFTSEQEA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 199 LQFFPRSMRQRGWVIPNMADWQHFKPRFTNT--------IRVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKG 270
Cdd:cd03821 165 DELRRFGLEPPIAVIPNGVDIPEFDPGLRDRrkhngledRRIILFLGRIHPKKGLDLLIRAARKLAEQGRDWHLVIAGPD 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 271 PD-RDALQALAASLGIADRVEMPGVSSQPGSWI--VDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPFGPAEMISDk 347
Cdd:cd03821 245 DGaYPAFLQLQSSLGLGDRVTFTGPLYGEAKWAlyASADLFVLPSYSENFGNVVAEALACGLPVVITDKCGLSELVEAG- 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1784594042 348 vDGLLApDGDVPALAEALSKVMGDAGLRDRLGANAiRKARLFEpERIGglWEA 400
Cdd:cd03821 324 -CGVVV-DPNVSSLAEALAEALRDPADRKRLGEMA-RRARQVE-ENFS--WEA 370
|
|
| PRK09922 |
PRK09922 |
lipopolysaccharide 1,6-galactosyltransferase; |
208-368 |
2.83e-26 |
|
lipopolysaccharide 1,6-galactosyltransferase;
Pssm-ID: 182148 [Multi-domain] Cd Length: 359 Bit Score: 108.65 E-value: 2.83e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 208 QRGWVIPNMADWQHF---KPRFTNTIRVLTaVGRLT--DQKGFDLLLQAFAKVadrHLDWKLRVWGKGPDRDALQALAAS 282
Cdd:PRK09922 156 QRISVIYNPVEIKTIiipPPERDKPAVFLY-VGRLKfeGQKNVKELFDGLSQT---TGEWQLHIIGDGSDFEKCKAYSRE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 283 LGIADRVEMPGVSSQPgsW------IVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPFGPAEMISDKVDGLLAPDG 356
Cdd:PRK09922 232 LGIEQRIIWHGWQSQP--WevvqqkIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSDCMSGPRDIIKPGLNGELYTPG 309
|
170
....*....|..
gi 1784594042 357 DVPALAEALSKV 368
Cdd:PRK09922 310 NIDEFVGKLNKV 321
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
236-398 |
9.98e-26 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 106.62 E-value: 9.98e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 236 VGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQPGSWIVDADAFVLSSRYE 315
Cdd:cd04949 166 ISRLAPEKQLDHLIEAVAKAVKKVPEITLDIYGYGEEREKLKKLIEELHLEDNVFLKGYHSNLDQEYQDAYLSLLTSQME 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 316 GWGLVLGEAMAAGLPCVSFDCPFGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKARLFEPERIG 395
Cdd:cd04949 246 GFGLTLMEAIGHGLPVVSYDVKYGPSELIEDGENGYLIEKNNIDALADKIIELLNDPEKLQQFSEESYKIAEKYSTENVM 325
|
...
gi 1784594042 396 GLW 398
Cdd:cd04949 326 EKW 328
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
63-387 |
4.04e-25 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 105.44 E-value: 4.04e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 63 VVTF---LANRLVACGLRITIV--SF-EDGSAPPYYRCDPEVSITYL----GVPIGRRGKVKGLnafaarvaglrsqMDA 132
Cdd:cd03817 16 VATSvrnLARALEKRGHEVYVItpSDpGAEDEEEVVRYRSFSIPIRKyhrqHIPFPFKKAVIDR-------------IKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 133 VRPDLVISFLT-RTNVISVLAARNLRIPVIVS----------ERNNPQRQRPPLPWRVMRRLaYARAYGLVTMTQGALqf 201
Cdd:cd03817 83 LGPDIIHTHTPfSLGKLGLRIARKLKIPIVHTyhtmyedylhYIPKGKLLVKAVVRKLVRRF-YNHTDAVIAPSEKIK-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 202 fpRSMRQRGW-----VIPNMADWQHFKP----------RFTNTIRVLTAVGRLTDQKGFDLLLQAFAKVADRHlDWKLRV 266
Cdd:cd03817 160 --DTLREYGVkgpieVIPNGIDLDKFEKplnteerrklGLPPDEPILLYVGRLAKEKNIDFLLRAFAELKKEP-NIKLVI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 267 WGKGPDRDALQALAASLGIADRV---------EMPGVSSQpgswivdADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCP 337
Cdd:cd03817 237 VGDGPEREELKELARELGLADKViftgfvpreELPEYYKA-------ADLFVFASTTETQGLVYLEAMAAGLPVVAAKDP 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1784594042 338 fGPAEMISDKVDGLLAPDGDVPaLAEALSKVMGDAGLRDRLGANAIRKAR 387
Cdd:cd03817 310 -AASELVEDGENGFLFEPNDET-LAEKLLHLRENLELLRKLSKNAEISAR 357
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
305-407 |
9.93e-25 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 98.14 E-value: 9.93e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 305 ADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIR 384
Cdd:COG0438 21 ADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVG-GLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRLGEAARE 99
|
90 100
....*....|....*....|....
gi 1784594042 385 KARL-FEPERIGGLWEAMIFDVLA 407
Cdd:COG0438 100 RAEErFSWEAIAERLLALYEELLA 123
|
|
| GT4-like |
cd05844 |
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ... |
119-387 |
2.27e-24 |
|
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340860 [Multi-domain] Cd Length: 365 Bit Score: 103.30 E-value: 2.27e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 119 FAARVAGLRSQmdaVRPDLVISFLTRTNVISVLAARNLRIPVIVS-------ERNNPQRQRPPLPWRVMR--RLAYARAY 189
Cdd:cd05844 69 WSAPRLGGAAG---LAPALVHAHFGRDGVYALPLARALGVPLVVTfhgfditTSRAWLAASPGWPSQFQRhrRALQRPAA 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 190 GLVTMTQG------ALQFFPRSMRqrgwVIPNMADWQHFKPRFTNT-IRVLTAVGRLTDQKGFDLLLQAFAKVADRHLDW 262
Cdd:cd05844 146 LFVAVSGFirdrllARGLPAERIH----VHYIGIDPAKFAPRDPAErAPTILFVGRLVEKKGCDVLIEAFRRLAARHPTA 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 263 KLRVWGKGPDRDALQALAASLGiadRVEMPGVSSQP--GSWIVDADAFVLSS------RYEGWGLVLGEAMAAGLPCVSf 334
Cdd:cd05844 222 RLVIAGDGPLRPALQALAAALG---RVRFLGALPHAevQDWMRRAEIFCLPSvtaasgDSEGLGIVLLEAAACGVPVVS- 297
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1784594042 335 DCPFGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKAR 387
Cdd:cd05844 298 SRHGGIPEAILDGETGFLVPEGDVDALADALQALLADRALADRMGGAARAFVC 350
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
236-352 |
2.70e-23 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 97.47 E-value: 2.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 236 VGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQPG---SWIVDADAFVLSS 312
Cdd:cd01635 116 VGRLVPEKGIDLLLEALALLKARLPDLVLVLVGGGGEREEEEALAAALGLLERVVIIGGLVDDEvleLLLAAADVFVLPS 195
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1784594042 313 RYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLL 352
Cdd:cd01635 196 RSEGFGLVLLEAMAAGKPVIATDVG-GIPEFVVDGENGLL 234
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
212-400 |
4.08e-22 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 97.04 E-value: 4.08e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 212 VIPNMADWQHFKPRFTNTI----------RVLTAVGRLTDQKGFDLLLQAFAKVAdRHLDWKLRVWGKGPDRDALQALAA 281
Cdd:cd04962 168 VIHNFIDEDVFKRKPAGALkrrllappdeKVVIHVSNFRPVKRIDDVVRVFARVR-RKIPAKLLLVGDGPERVPAEELAR 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 282 SLGIADRVEMPGVSSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPAL 361
Cdd:cd04962 247 ELGVEDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAG-GIPEVVKHGETGFLSDVGDVDAM 325
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1784594042 362 AEALSKVMGDAGLRDRLGANAIRKAR-LFEPERIGGLWEA 400
Cdd:cd04962 326 AKSALSILEDDELYNRMGRAARKRAAeRFDPERIVPQYEA 365
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
53-386 |
6.18e-21 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 93.55 E-value: 6.18e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 53 PALGAGGSEHVVTFLANRLVACGLRITIVSFEDGSAP---------PYYRCDPEVsiTYLGVPIGRRGKVKGLNAFAARV 123
Cdd:cd03823 10 PPQRVGGAEISVHDLAEALVAEGHEVAVLTAGVGPPGqatvarsvvRYRRAPDET--LPLALKRRGYELFETYNPGLRRL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 124 agLRSQMDAVRPDLV-ISFLTRTNVISVLAARNLRIPVIVSERNnpqrqrPPL--PWRVMRRLAYARAYGLVTMTQGALQ 200
Cdd:cd03823 88 --LARLLEDFRPDVVhTHNLSGLGASLLDAARDLGIPVVHTLHD------YWLlcPRQFLFKKGGDAVLAPSRFTANLHE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 201 --FFPRSMRQrgwVIPNMADWQHF---KPRFTNTIRVLTAVGRLTDQKGFDLLLQAFAKVAdrHLDWKLRVWGKGPDRDA 275
Cdd:cd03823 160 anGLFSARIS---VIPNAVEPDLApppRRRPGTERLRFGYIGRLTEEKGIDLLVEAFKRLP--REDIELVIAGHGPLSDE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 276 LQALA----ASLGIADRVEMPGVSSQpgswivdADAFVLSSR-YEGWGLVLGEAMAAGLPCVSFDcPFGPAEMISDKVDG 350
Cdd:cd03823 235 RQIEGgrriAFLGRVPTDDIKDFYEK-------IDVLVVPSIwPEPFGLVVREAIAAGLPVIASD-LGGIAELIQPGVNG 306
|
330 340 350
....*....|....*....|....*....|....*.
gi 1784594042 351 LLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKA 386
Cdd:cd03823 307 LLFAPGDAEDLAAAMRRLLTDPALLERLRAGAEPPR 342
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
152-382 |
7.55e-21 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 93.13 E-value: 7.55e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 152 AARNLRIPVIVSERNN-----PQRQRPPLP---WRVMRRLaYARAYGLVTMTqgalqffpRSMRQ--RGWVIPNMADWQH 221
Cdd:cd03814 103 AARRLGLPVVTSYHTDfpeylSYYTLGPLSwlaWAYLRWF-HNPFDTTLVPS--------PSIARelEGHGFERVRLWPR 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 222 ------FKPRFTNTI----------RVLTAVGRLTDQKGFDLLLQAFAKVADrHLDWKLRVWGKGPDRDALQAL---AAS 282
Cdd:cd03814 174 gvdtelFHPSRRDAAlrrrlgppgrPLLLYVGRLAPEKNLEALLDADLPLAA-SPPVRLVVVGDGPARAELEARgpdVIF 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 283 LGIADRVEmpgVSSQPGSwivdADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPALA 362
Cdd:cd03814 253 TGFLTGEE---LARAYAS----ADVFVFPSRTETFGLVVLEAMASGLPVVAADAG-GPRDIVRPGGTGALVEPGDAAAFA 324
|
250 260
....*....|....*....|
gi 1784594042 363 EALSKVMGDAGLRDRLGANA 382
Cdd:cd03814 325 AALRALLEDPELRRRMAARA 344
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
235-401 |
5.38e-20 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 90.89 E-value: 5.38e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 235 AVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWG-KGPDRDALQALAASLGIADRVEMPGvssqpgsWIVD--------- 304
Cdd:cd03809 197 YVGTLEPRKNHERLLKAFALLKKQGGDLKLVIVGgKGWEDEELLDLVKKLGLGGRVRFLG-------YVSDedlpalyrg 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 305 ADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDcpfGPA--EMISDkvDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANA 382
Cdd:cd03809 270 ARAFVFPSLYEGFGLPVLEAMACGTPVIASN---ISVlpEVAGD--AALYFDPLDPESIADAILRLLEDPSLREELIRKG 344
|
170
....*....|....*....
gi 1784594042 383 IRKARLFEperigglWEAM 401
Cdd:cd03809 345 LERAKKFS-------WEKT 356
|
|
| GT4_AmsK-like |
cd03799 |
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ... |
222-373 |
3.69e-19 |
|
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.
Pssm-ID: 340829 [Multi-domain] Cd Length: 350 Bit Score: 88.28 E-value: 3.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 222 FKPRF---TNTIRVLTaVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQP 298
Cdd:cd03799 164 FKPRYlplDGKIRILT-VGRLTEKKGLEYAIEAVAKLAQKYPNIEYQIIGDGDLKEQLQQLIQELNIGDCVKLLGWKPQE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 299 GswIVD----ADAFVLSS------RYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPALAEALSKV 368
Cdd:cd03799 243 E--IIEildeADIFIAPSvtaadgDQDGPPNTLKEAMAMGLPVISTEHG-GIPELVEDGVSGFLVPERDAEAIAEKLTYL 319
|
170
....*....|....
gi 1784594042 369 ---------MGDAG 373
Cdd:cd03799 320 iehpaiwpeMGKAG 333
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
212-386 |
4.62e-19 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 88.16 E-value: 4.62e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 212 VIPNMADWQHFKPRFTNTIR-----------VLTAVGRLTDQ-KGFDLLLQAFAKvADRHLDWKLRVWGKGPDRDALQAL 279
Cdd:cd03825 165 VIPNGIDTEIFAPVDKAKARkrlgipqdkkvILFGAESVTKPrKGFDELIEALKL-LATKDDLLLVVFGKNDPQIVILPF 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 280 AA-SLG-IADRVEMPGVSSQpgswivdADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGD 357
Cdd:cd03825 244 DIiSLGyIDDDEQLVDIYSA-------ADLFVHPSLADNLPNTLLEAMACGTPVVAFDTG-GSPEIVQHGVTGYLVPPGD 315
|
170 180
....*....|....*....|....*....
gi 1784594042 358 VPALAEALSKVMGDAGLRDRLGANAIRKA 386
Cdd:cd03825 316 VQALAEAIEWLLANPKERESLGERARALA 344
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
58-382 |
2.48e-18 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 86.24 E-value: 2.48e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 58 GGSEHVVTFLANRLVACGLRITIVSfedgsAPPYY---RCDPEVSITYLGV--------PIGRRGKVK-GLNAFAARVAG 125
Cdd:cd03794 14 GAAAARVYELAKELVRRGHEVTVLT-----PSPNYplgRIFAGATETKDGIrvirvklgPIKKNGLIRrLLNYLSFALAA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 126 LRS-QMDAVRPDLVISF---LTrTNVISVLAARNLRIPVIVSERN-NPQRQ------RPPLPWRVMR---RLAYARAYGL 191
Cdd:cd03794 89 LLKlLVREERPDVIIAYsppIT-LGLAALLLKKLRGAPFILDVRDlWPESLialgvlKKGSLLKLLKkleRKLYRLADAI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 192 VTMTQGALQFF-PRSMR-QRGWVIPNMADWQHFKPRFTNTIRVLTA---------VGRLTDQKGFDLLLQAFAKVADRHl 260
Cdd:cd03794 168 IVLSPGLKEYLlRKGVPkEKIIVIPNWADLEEFKPPPKDELRKKLGlddkfvvvyAGNIGKAQGLETLLEAAERLKRRP- 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 261 DWKLRVWGKGPDRDALQALAASLGIADRVEMPGVS-SQPGSWIVDADA--FVLSSRYEGWGLV---LGEAMAAGLPcVSF 334
Cdd:cd03794 247 DIRFLFVGDGDEKERLKELAKARGLDNVTFLGRVPkEEVPELLSAADVglVPLKDNPANRGSSpskLFEYMAAGKP-ILA 325
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1784594042 335 DCPFGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANA 382
Cdd:cd03794 326 SDDGGSDLAVEINGCGLVVEPGDPEALADAILELLDDPELRRAMGENG 373
|
|
| GT4_WfcD-like |
cd03795 |
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ... |
235-390 |
3.09e-18 |
|
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340826 [Multi-domain] Cd Length: 355 Bit Score: 85.40 E-value: 3.09e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 235 AVGRLTDQKGFDLLLQAFakvadRHLDWKLRVWGKGPDRDALQALAAsLGIADRVEMPGVSSQpgswiVD-------ADA 307
Cdd:cd03795 196 FIGRLVYYKGLDYLIEAA-----QYLNYPIVIGGEGPLKPDLEAQIE-LNLLDNVKFLGRVDD-----EEkviylhlCDV 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 308 FVLSS--RYEGWGLVLGEAMAAGLPCVSFDCPFGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAirK 385
Cdd:cd03795 265 FVFPSvlRSEAFGIVLLEAMMCGKPVISTNIGTGVPYVNNNGETGLVVPPKDPDALAEAIDKLLSDEELRESYGENA--K 342
|
....*
gi 1784594042 386 ARLFE 390
Cdd:cd03795 343 KRFEE 347
|
|
| PRK15179 |
PRK15179 |
Vi polysaccharide biosynthesis protein TviE; Provisional |
217-377 |
9.93e-17 |
|
Vi polysaccharide biosynthesis protein TviE; Provisional
Pssm-ID: 185101 [Multi-domain] Cd Length: 694 Bit Score: 82.39 E-value: 9.93e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 217 ADWQHFKPRFTNTIRVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSS 296
Cdd:PRK15179 504 AMMAQFDARTSDARFTVGTVMRVDDNKRPFLWVEAAQRFAASHPKVRFIMVGGGPLLESVREFAQRLGMGERILFTGLSR 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 297 QPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSfdCPFGPA-EMISDKVDGLLAPDGDV--PALAEALSKVM---- 369
Cdd:PRK15179 584 RVGYWLTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVT--TLAGGAgEAVQEGVTGLTLPADTVtaPDVAEALARIHdmca 661
|
....*...
gi 1784594042 370 GDAGLRDR 377
Cdd:PRK15179 662 ADPGIARK 669
|
|
| stp2 |
TIGR03088 |
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ... |
232-386 |
1.51e-16 |
|
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.
Pssm-ID: 132132 [Multi-domain] Cd Length: 374 Bit Score: 80.54 E-value: 1.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 232 VLTAVGRLTDQKGFDLLLQAFAKV----ADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQPGSWIVDADA 307
Cdd:TIGR03088 196 VVGTVGRLQAVKDQPTLVRAFALLvrqlPEGAERLRLVIVGDGPARGACEQMVRAAGLAHLVWLPGERDDVPALMQALDL 275
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1784594042 308 FVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKA 386
Cdd:TIGR03088 276 FVLPSLAEGISNTILEAMASGLPVIATAVG-GNPELVQHGVTGALVPPGDAVALARALQPYVSDPAARRAHGAAGRARA 353
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
182-393 |
1.53e-15 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 78.15 E-value: 1.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 182 RLAYARAYGLVTMTQGALQF------FPRSMRqrgwVIPNMADWQHFKP----RFTNTIRVLTAVGRLTDQKGFDLLLQA 251
Cdd:cd03813 239 KLAYQQADKIISLYEGNRRRqirlgaDPDKTR----VIPNGIDIQRFAPareeRPEKEPPVVGLVGRVVPIKDVKTFIRA 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 252 FAKVADRHLDWKLRVWGkGPDRDAL-----QALAASLGIADRVEMPGVSSqpgswIVDA----DAFVLSSRYEGWGLVLG 322
Cdd:cd03813 315 FKLVRRAMPDAEGWLIG-PEDEDPEyaqecKRLVASLGLENKVKFLGFQN-----IKEYypklGLLVLTSISEGQPLVIL 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 323 EAMAAGLPCVSFD---CPfgpaEMISDKVD-----GLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKA-RLFEPER 393
Cdd:cd03813 389 EAMASGVPVVATDvgsCR----ELIYGADDalgqaGLVVPPADPEALAEALIKLLRDPELRQAFGEAGRKRVeKYYTLEG 464
|
|
| GT4_CapH-like |
cd03812 |
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ... |
232-351 |
2.33e-15 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).
Pssm-ID: 340840 [Multi-domain] Cd Length: 357 Bit Score: 76.94 E-value: 2.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 232 VLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQPGSWIVDADAFVLS 311
Cdd:cd03812 193 VLGHVGRFNEQKNHSFLIDIFEELKKKNPNVKLVLVGEGELKEKIKEKVKELGLEDKVIFLGFRNDVSEILSAMDVFLFP 272
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1784594042 312 SRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGL 351
Cdd:cd03812 273 SLYEGLPLVAVEAQASGLPCLLSDTI-TKECDITNNVEFL 311
|
|
| GT4_PIG-A-like |
cd03796 |
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ... |
212-368 |
1.80e-11 |
|
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.
Pssm-ID: 340827 [Multi-domain] Cd Length: 398 Bit Score: 65.34 E-value: 1.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 212 VIPNMADWQHFKP----RFTNTIRVLTaVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIAD 287
Cdd:cd03796 172 VIPNAVDSSDFTPdpskPDPNKITIVV-ISRLVYRKGIDLLVGIIPRICKKHPNVRFIIGGDGPKRIELEEMREKYQLQD 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 288 RVEMPGV--SSQPGSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCpfG------PAEMIsdkvdgLLA---PDG 356
Cdd:cd03796 251 RVELLGAvpHEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVSTRV--GgipevlPPDMI------LLAepdPED 322
|
170
....*....|..
gi 1784594042 357 DVPALAEALSKV 368
Cdd:cd03796 323 IVRKLEEAISIL 334
|
|
| Glyco_trans_4_4 |
pfam13579 |
Glycosyl transferase 4-like domain; |
58-215 |
8.49e-10 |
|
Glycosyl transferase 4-like domain;
Pssm-ID: 433325 [Multi-domain] Cd Length: 158 Bit Score: 57.03 E-value: 8.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 58 GGSEHVVTFLANRLVACGLRITIVSFEDGSAPPYYRcdpEVSITYLGVPIGRRGKVKGLnafAARVAGLRSQMDAVRPDL 137
Cdd:pfam13579 1 GGIGVYVLELARALAALGHEVRVVTPGGPPGRPELV---GDGVRVHRLPVPPRPSPLAD---LAALRRLRRLLRAERPDV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 138 VISFLTRTNVISVLAARNLRIPVIVSERNN-PQRQRPPLPW--RVMRRLAYARAYGLVTMTQGALQFFPRS--MRQRGWV 212
Cdd:pfam13579 75 VHAHSPTAGLAARLARRRRGVPLVVTVHGLaLDYGSGWKRRlaRALERRLLRRADAVVVVSEAEAELLRALgvPAARVVV 154
|
...
gi 1784594042 213 IPN 215
Cdd:pfam13579 155 VPN 157
|
|
| PRK15490 |
PRK15490 |
Vi polysaccharide biosynthesis glycosyltransferase TviE; |
219-364 |
1.03e-09 |
|
Vi polysaccharide biosynthesis glycosyltransferase TviE;
Pssm-ID: 185387 [Multi-domain] Cd Length: 578 Bit Score: 60.48 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 219 WQHFKPRFTNTIRVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRDALQALAASLGIADRVEMPGVSSQP 298
Cdd:PRK15490 387 WQQFTQKTQDADTTIGGVFRFVGDKNPFAWIDFAARYLQHHPATRFVLVGDGDLRAEAQKRAEQLGILERILFVGASRDV 466
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1784594042 299 GSWIVDADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDVPALAEA 364
Cdd:PRK15490 467 GYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTPAG-GSAECFIEGVSGFILDDAQTVNLDQA 531
|
|
| MSMEG_0565_glyc |
TIGR04047 |
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from ... |
208-380 |
1.93e-08 |
|
glycosyltransferase, MSMEG_0565 family; A conserved gene cluster found sporadically from Actinobacteria to Proteobacteria to Cyanobacteria features a radical SAM protein, an N-acetyltransferase, an oxidoreductase, and two additional proteins whose functional classes are unclear. The metabolic role of the cluster is probably biosynthetic. This glycosyltransferase, named from member MSMEG_0565 from Mycobacterium smegmatis, occurs in most but not all instances of the cluster. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 274943 [Multi-domain] Cd Length: 373 Bit Score: 55.87 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 208 QRGW-----VIPNMADWQHFKP-----------RFTNTI-RVLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWG-- 268
Cdd:TIGR04047 154 RAEWgidatVVPNGVDAARFSPaadaadaalrrRLGLRGgPYVLAVGGIEPRKNTIDLLEAFALLRARRPQAQLVIAGga 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 269 ----KGPDRDALQALAASLGIA----------DRVEMPGVSSQpgswivdADAFVLSSRYEGWGLVLGEAMAAGLPCVSF 334
Cdd:TIGR04047 234 tlfdYDAYRREFRARAAELGVDpgpvvitgpvPDADLPALYRC-------ADAFAFPSLKEGFGLVVLEALASGIPVVAS 306
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1784594042 335 DCPfgPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGA 380
Cdd:TIGR04047 307 DIA--PFTEYLGRFDAAWADPSDPDSIADALALALDPARRPALRAA 350
|
|
| PLN02871 |
PLN02871 |
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase |
200-400 |
2.11e-07 |
|
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
Pssm-ID: 215469 [Multi-domain] Cd Length: 465 Bit Score: 52.79 E-value: 2.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 200 QFFPR----SMRQRgwvipnMADWQHFKPrftntirVLTAVGRLTDQKGFDLLlqafAKVADRHLDWKLRVWGKGPDRDA 275
Cdd:PLN02871 242 SFHPRfrseEMRAR------LSGGEPEKP-------LIVYVGRLGAEKNLDFL----KRVMERLPGARLAFVGDGPYREE 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 276 LQALAASLGIADRVEMPG--VSSQPGSwivdADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDG--- 350
Cdd:PLN02871 305 LEKMFAGTPTVFTGMLQGdeLSQAYAS----GDVFVMPSESETLGFVVLEAMASGVPVVAARAG-GIPDIIPPDQEGktg 379
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1784594042 351 LLAPDGDVPALAEALSKVMGDAGLRDRLGANAiRKarlfEPERIGglWEA 400
Cdd:PLN02871 380 FLYTPGDVDDCVEKLETLLADPELRERMGAAA-RE----EVEKWD--WRA 422
|
|
| Glyco_transf_4 |
pfam13439 |
Glycosyltransferase Family 4; |
58-215 |
7.69e-07 |
|
Glycosyltransferase Family 4;
Pssm-ID: 463877 [Multi-domain] Cd Length: 169 Bit Score: 49.07 E-value: 7.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 58 GGSEHVVTFLANRLVACGLRITIVSFEDGSAPPyyrcdpEVSITYLGVPIGRRGKVKGLNAFAARVAGLRSQMDAVRPDL 137
Cdd:pfam13439 1 GGVERYVLELARALARRGHEVTVVTPGGPGPLA------EEVVRVVRVPRVPLPLPPRLLRSLAFLRRLRRLLRRERPDV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 138 VISFLTRTNVISVLAARN-LRIPVIVSE---------RNNPQRQRPPLPWRVMRRLaYARAYGLVTMTQGALQFFPRSM- 206
Cdd:pfam13439 75 VHAHSPFPLGLAALAARLrLGIPLVVTYhglfpdykrLGARLSPLRRLLRRLERRL-LRRADRVIAVSEAVADELRRLYg 153
|
170
....*....|.
gi 1784594042 207 --RQRGWVIPN 215
Cdd:pfam13439 154 vpPEKIRVIPN 164
|
|
| GT4_WbaZ-like |
cd03804 |
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ... |
235-366 |
7.88e-07 |
|
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.
Pssm-ID: 340833 [Multi-domain] Cd Length: 356 Bit Score: 50.75 E-value: 7.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 235 AVGRLTDQKGFDLLLQAFAKvadrhLDWKLRVWGKGPDRDALQALAaslgiADRVEMPGVSSQP--GSWIVDADAFVLSS 312
Cdd:cd03804 204 TASRLVPYKRIDLAVEAFNE-----LPKRLVVIGDGPDLDRLRAMA-----SPNVEFLGYQPDEvlKELLSKARAFVFAA 273
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1784594042 313 RyEGWGLVLGEAMAAGLPCVSFDcPFGPAEMISDKVDGLLAPDGDVPALAEALS 366
Cdd:cd03804 274 E-EDFGIVPVEAQACGTPVIAFG-KGGALETVRPGPTGILFGEQTVESLKAAVE 325
|
|
| GT4_ExpC-like |
cd03818 |
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ... |
190-386 |
1.11e-06 |
|
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).
Pssm-ID: 340845 [Multi-domain] Cd Length: 396 Bit Score: 50.44 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 190 GLVTMTQGALQFFPRSMRQRGWVIPNMADWQHFKP------------RFTNTIRVLTAVGR-LTDQKGFDLLLQAFAKVA 256
Cdd:cd03818 161 LGVTPTRWQRSLFPAAYRDRISVIHDGVDTDRLAPdpaarlrllngtELKAGDPVITYVARnLEPYRGFHVFMRALPRIQ 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 257 DRHLDWKLRVWGK------GPDRDA----LQALAASLGIADRVEMPGVssqpgswiVDADAFVLSSR---------YEG- 316
Cdd:cd03818 241 ARRPDARVVVVGGdgvsygSPPPDGgswkQKMLAELGVDLERVHFVGK--------VPYDQYVRLLQlsdahvyltYPFv 312
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1784594042 317 --WGLVlgEAMAAGLPCVSFDCPFGPaEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLGANAIRKA 386
Cdd:cd03818 313 lsWSLL--EAMACGCPVIGSDTAPVR-EVIRDGRNGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTV 381
|
|
| GT4_mannosyltransferase-like |
cd03822 |
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ... |
232-395 |
4.01e-06 |
|
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.
Pssm-ID: 340849 [Multi-domain] Cd Length: 370 Bit Score: 48.54 E-value: 4.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 232 VLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWG-------KGPDRDALQALAASLGIADRVEMP--GVSSQP-GSW 301
Cdd:cd03822 189 VILTFGFIGPGKGLEILLEALPELKAEFPDVRLVIAGelhpslaRYEGERYRKAAIEELGLQDHVDFHnnFLPEEEvPRY 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 302 IVDADAFVLSSRYEGWGL--VLGEAMAAGLPCVSfdCPFGPAEMISDKVDGLLAPDGDVPALAEALSKVMGDAGLRDRLG 379
Cdd:cd03822 269 ISAADVVVLPYLNTEQSSsgTLSYAIACGKPVIS--TPLRHAEELLADGRGVLVPFDDPSAIAEAILRLLEDDERRQAIA 346
|
170
....*....|....*.
gi 1784594042 380 ANAIRKARLFEPERIG 395
Cdd:cd03822 347 ERAYAYARAMTWESIA 362
|
|
| GT4_ALG2-like |
cd03805 |
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ... |
243-390 |
1.00e-05 |
|
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.
Pssm-ID: 340834 [Multi-domain] Cd Length: 392 Bit Score: 47.58 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 243 KGFDLLLQAFAKVADRHLDW---KLRVWGkGPDR---------DALQALAASL-GIADRVE-MPGVSSQPGSWIVD-ADA 307
Cdd:cd03805 224 KNIALAIEAFAKLKQKLPEFenvRLVIAG-GYDPrvaenveylEELQRLAEELlNVEDQVLfLRSISDSQKEQLLSsALA 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 308 FVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLApDGDVPALAEALSKVMGDAGLRDRLGANAirKAR 387
Cdd:cd03805 303 LLYTPSNEHFGIVPLEAMYAGKPVIACNSG-GPLETVVEGVTGFLC-EPTPEAFAEAMLKLANDPDLADRMGAAG--RKR 378
|
...
gi 1784594042 388 LFE 390
Cdd:cd03805 379 VKE 381
|
|
| GT5_Glycogen_synthase_DULL1-like |
cd03791 |
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ... |
236-332 |
1.93e-05 |
|
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
Pssm-ID: 340822 [Multi-domain] Cd Length: 474 Bit Score: 46.79 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 236 VGRLTDQKGFDLLLQAFAKVadRHLDWKLRVWGKGPDR--DALQALAAslgiadrvEMPG-VSSQPGswiVD-------- 304
Cdd:cd03791 300 VGRLTEQKGVDLILDALPEL--LEEGGQLVVLGSGDPEyeQAFRELAE--------RYPGkVAVVIG---FDealahriy 366
|
90 100 110
....*....|....*....|....*....|
gi 1784594042 305 --ADAFVLSSRYEGWGLVLGEAMAAGLPCV 332
Cdd:cd03791 367 agADFFLMPSRFEPCGLVQMYAMRYGTLPI 396
|
|
| GT4_AviGT4-like |
cd03802 |
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ... |
212-369 |
2.96e-05 |
|
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.
Pssm-ID: 340832 [Multi-domain] Cd Length: 333 Bit Score: 45.74 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 212 VIPNMADWQHFKPRFtNTIRVLTAVGRLTDQKGfdlLLQAfAKVAdRHLDWKLRVWGKGPDRDA---LQALAASLGIADR 288
Cdd:cd03802 152 VVHNGLDPADYRFQP-DPEDYLAFLGRIAPEKG---LEDA-IRVA-RRAGLPLKIAGKVRDEDYfyyLQEPLPGPRIEFI 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 289 VEMPGvsSQPGSWIVDADAFVLSSRY-EGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDvpALAEALSK 367
Cdd:cd03802 226 GEVGH--DEKQELLGGARALLFPINWdEPFGLVMIEAMACGTPVIAYRRG-GLPEVIQHGETGFLVDSVE--EMAEAIAN 300
|
..
gi 1784594042 368 VM 369
Cdd:cd03802 301 ID 302
|
|
| PelF |
NF038011 |
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ... |
182-373 |
9.90e-05 |
|
GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.
Pssm-ID: 411604 [Multi-domain] Cd Length: 489 Bit Score: 44.54 E-value: 9.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 182 RLAYARAYGLVTMTQGALQffpRSM-----RQRGWVIPNMADWQHFKP----RFTNTIRVLTAVGRLTDQKGFDLLLQAF 252
Cdd:NF038011 252 RLCYDAADPIVALYEGNRL---RQIadgapPERTRVIPNGIDLPRLAPlraqRPAGIPPVVGLIGRVVPIKDIKTFIRAM 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 253 AKVADRHLDwkLRVWGKGP---DRDALQ---ALAASLGIADRVEMPGVSSqpgswIVD----ADAFVLSSRYEGWGLVLG 322
Cdd:NF038011 329 RTVVRAMPE--AEGWIVGPeeeDPAYAAecrSLVASLGLQDKVKFLGFQK-----IDDllpqVGLMVLSSISEALPLVVL 401
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1784594042 323 EAMAAGLPCVSFD---CpfgpAEMI--SDKVDGLLAPDGDV------PALAEALSKVMGDAG 373
Cdd:NF038011 402 EAFAAGVPVVTTDvgsC----RQLIegLDEEDRALGAAGEVvaiadpQALARAALDLLRDPQ 459
|
|
| PRK15484 |
PRK15484 |
lipopolysaccharide N-acetylglucosaminyltransferase; |
212-330 |
1.02e-04 |
|
lipopolysaccharide N-acetylglucosaminyltransferase;
Pssm-ID: 185381 [Multi-domain] Cd Length: 380 Bit Score: 44.40 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 212 VIPNMADWQHFKPRFTNTIR----------VLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWG---------KGPD 272
Cdd:PRK15484 165 IVPNGFCLETYQSNPQPNLRqqlnispdetVLLYAGRISPDKGILLLMQAFEKLATAHSNLKLVVVGdptasskgeKAAY 244
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1784594042 273 RDALQALAASLGiaDRVEMPGvsSQPGSWIVD----ADAFVLSSRY-EGWGLVLGEAMAAGLP 330
Cdd:PRK15484 245 QKKVLEAAKRIG--DRCIMLG--GQPPEKMHNyyplADLVVVPSQVeEAFCMVAVEAMAAGKP 303
|
|
| PLN00142 |
PLN00142 |
sucrose synthase |
307-350 |
1.09e-04 |
|
sucrose synthase
Pssm-ID: 215073 [Multi-domain] Cd Length: 815 Bit Score: 44.58 E-value: 1.09e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1784594042 307 AFVLSSRYEGWGLVLGEAMAAGLPCVSfDCPFGPAEMISDKVDG 350
Cdd:PLN00142 669 AFVQPALYEAFGLTVVEAMTCGLPTFA-TCQGGPAEIIVDGVSG 711
|
|
| GT4_AmsK-like |
cd04946 |
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ... |
232-388 |
4.36e-04 |
|
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.
Pssm-ID: 340854 [Multi-domain] Cd Length: 401 Bit Score: 42.45 E-value: 4.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 232 VLTAVGRLtdqkgfDLLLQAFAKVADRHLDWKLRvW---GKGPDRDALQALAASLGIADRVEMPGVSSQPG--SWIV--D 304
Cdd:cd04946 232 SIVPVKRI------DLIIETLNSLCVAHPSICIS-WthiGGGPLKERLEKLAENKLENVKVNFTGEVSNKEvkQLYKenD 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 305 ADAFVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLaPDGD--VPALAEALSKVMGDAGLRDRLGANA 382
Cdd:cd04946 305 VDVFVNVSESEGIPVSIMEAISFGIPVIATNVG-GTREIVENETNGLL-LDKDptPNEIVSSIMKFYLDGGDYKTMKISA 382
|
....*.
gi 1784594042 383 IRKARL 388
Cdd:cd04946 383 RECWEE 388
|
|
| GlgA |
COG0297 |
Glycogen synthase [Carbohydrate transport and metabolism]; |
232-281 |
6.38e-04 |
|
Glycogen synthase [Carbohydrate transport and metabolism];
Pssm-ID: 440066 [Multi-domain] Cd Length: 476 Bit Score: 42.00 E-value: 6.38e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1784594042 232 VLTAVGRLTDQKGFDLLLQAFAKVADRhlDWKLRVWGKGPDR--DALQALAA 281
Cdd:COG0297 297 LIGMVSRLTEQKGLDLLLEALDELLEE--DVQLVVLGSGDPEyeEAFRELAA 346
|
|
| PRK10307 |
PRK10307 |
colanic acid biosynthesis glycosyltransferase WcaI; |
237-409 |
2.55e-03 |
|
colanic acid biosynthesis glycosyltransferase WcaI;
Pssm-ID: 236670 [Multi-domain] Cd Length: 412 Bit Score: 39.96 E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 237 GRLTDQKGFDLLLQAFAKVADRHlDWKLRVWGKGPDRDALQALAASLGIADRVEMPgvsSQP----GSWIVDADAFVLSS 312
Cdd:PRK10307 236 GNIGEKQGLELVIDAARRLRDRP-DLIFVICGQGGGKARLEKMAQCRGLPNVHFLP---LQPydrlPALLKMADCHLLPQ 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 313 RYEGWGLV----LGEAMAAGLPCVSFdcpfgpAEM---ISDKVD--GLLAPDGDVPALAEALSKVMGDAGLRDRLGANAI 383
Cdd:PRK10307 312 KAGAADLVlpskLTNMLASGRNVVAT------AEPgteLGQLVEgiGVCVEPESVEALVAAIAALARQALLRPKLGTVAR 385
|
170 180
....*....|....*....|....*..
gi 1784594042 384 RKA-RLFEPERIGGLWEAMIFDVLASR 409
Cdd:PRK10307 386 EYAeRTLDKENVLRQFIADIRGLVAER 412
|
|
| GT4_trehalose_phosphorylase |
cd03792 |
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ... |
232-382 |
3.19e-03 |
|
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.
Pssm-ID: 340823 [Multi-domain] Cd Length: 378 Bit Score: 39.61 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 232 VLTAVGRLTDQKGFDLLLQAFAKVADRHLDWKLRVWGKGPDRD---AL---QALAASLGIAD--RVEMPGVSS-----QP 298
Cdd:cd03792 199 YILQVARFDPSKDPLGVIDAYKLFKRRAEEPQLVICGHGAVDDpegSVvyeEVMEYAGDDHDihVLRLPPSDQeinalQR 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784594042 299 GSWIVdadafVLSSRYEGWGLVLGEAMAAGLPCVSFDCPfGPAEMISDKVDGLLAPDGDvpALAEALSKVMGDAGLRDRL 378
Cdd:cd03792 279 AATVV-----LQLSTREGFGLTVSEALWKGKPVIATPAG-GIPLQVIDGETGFLVNSVE--GAAVRILRLLTDPELRRKM 350
|
....
gi 1784594042 379 GANA 382
Cdd:cd03792 351 GLAA 354
|
|
| |
