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Conserved domains on  [gi|1154824142|ref|WP_078737543|]
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hypothetical protein [Porphyromonas circumdentaria]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Autotransporter super family cl47048
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
73-149 4.34e-03

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.


The actual alignment was detected with superfamily member smart00869:

Pssm-ID: 214872 [Multi-domain]  Cd Length: 268  Bit Score: 37.16  E-value: 4.34e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1154824142   73 NDTWGVGVFFSYDYSAARENRAQIFSHSYSITPFVRYYYFHRLPFNLYLDTCVGGNWSTEKHQQLEGLGGIDVERAN 149
Cdd:smart00869  39 NGNLSLGFAAGYGNSKVDFSGNKGSGKGDVDSYGLGLYAGYSLGNGLYLDAQLGYGRSDNDTKRKVTLGGAGRAKGS 115
 
Name Accession Description Interval E-value
Autotransporter smart00869
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
73-149 4.34e-03

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.


Pssm-ID: 214872 [Multi-domain]  Cd Length: 268  Bit Score: 37.16  E-value: 4.34e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1154824142   73 NDTWGVGVFFSYDYSAARENRAQIFSHSYSITPFVRYYYFHRLPFNLYLDTCVGGNWSTEKHQQLEGLGGIDVERAN 149
Cdd:smart00869  39 NGNLSLGFAAGYGNSKVDFSGNKGSGKGDVDSYGLGLYAGYSLGNGLYLDAQLGYGRSDNDTKRKVTLGGAGRAKGS 115
 
Name Accession Description Interval E-value
Autotransporter smart00869
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
73-149 4.34e-03

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.


Pssm-ID: 214872 [Multi-domain]  Cd Length: 268  Bit Score: 37.16  E-value: 4.34e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1154824142   73 NDTWGVGVFFSYDYSAARENRAQIFSHSYSITPFVRYYYFHRLPFNLYLDTCVGGNWSTEKHQQLEGLGGIDVERAN 149
Cdd:smart00869  39 NGNLSLGFAAGYGNSKVDFSGNKGSGKGDVDSYGLGLYAGYSLGNGLYLDAQLGYGRSDNDTKRKVTLGGAGRAKGS 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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