|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
1-444 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 941.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 1 MFTRVANFCRKVLSREESMANDAIAQNRMSVIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 80
Cdd:PRK11623 8 IFTRVANFCRKVLSREESEAEQAVARPQMTVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 81 FDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEAGESDRTTSQRGQNGMLLRDNIFGSIEEDAQR 160
Cdd:PRK11623 88 FDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESDRNTSQRGQNGMLLRDNIFGSIEEDAQR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 161 RDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTPETRYREDPVRMLRAVRFAAKLSMRISPETAEPIPRLATLIND 240
Cdd:PRK11623 168 RDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLND 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 241 VPPARLFEEALKLLQAGYGYETYKLLREYSLFQPLFPTITRCFTENGDSPMERMIAQVLKNTDTRIHNDMRVNPAFLFAA 320
Cdd:PRK11623 248 IPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 321 MFWYPLLEAAQRIAQESGLAYYDAFALAANDVLDEACRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 400
Cdd:PRK11623 328 MFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 407
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1102824196 401 FDLLSLRAEIERNQELQRLAQWWGEFQVSAPPEQKDMLVDLDDE 444
Cdd:PRK11623 408 YDLLALRAEVENNAELQRLAQWWGEFQVSAPPQQKGMLNELDDD 451
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
31-437 |
2.92e-166 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 474.67 E-value: 2.92e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 31 VIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAH 110
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 111 VMFGPEIIEVATFRGHHEagesdrttSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDG 190
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGHK--------SSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 191 LIRLIGTPETRYREDPVRMLRAVRFAAKLSMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGYGYETYKLLREYS 270
Cdd:TIGR01942 153 RLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 271 LFQPLFPTITRCFTENGDSPMERMIAQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLEAAQRIAQEsGLAYYDAFALAAN 350
Cdd:TIGR01942 233 LLEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 351 DVLDEACRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAFDLLSLRAEIERnqELQRLAQWWGEFQVSA 430
Cdd:TIGR01942 312 DFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVCGR--ENAVLGEWWTPYQLAS 389
|
....*..
gi 1102824196 431 PPEQKDM 437
Cdd:TIGR01942 390 EEERTEM 396
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
43-427 |
1.18e-124 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 367.99 E-value: 1.18e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 43 DISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFR---NCRLVGRRFRLAHVMFGPEIIE 119
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 120 VATFRGHHEAGESDRTtsqrgqngmllrDNIFG-SIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTP 198
Cdd:COG0617 81 VATARTERYYGDGRRP------------FVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 199 ETRYREDPVRMLRAVRFAAKLSMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGYGYETYKLLREYSLFQPLfpt 278
Cdd:COG0617 149 EERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 279 itrcftengdspmermiaqvlkntdtrihndmrvnpAFLFAAMFwYPLLEAAQRiaqESGLAYYDAFALAANDVLDEACR 358
Cdd:COG0617 226 ------------------------------------ALRLAALL-HDLGKPATR---EDGLPTFHGHEEAGAELAEALLK 265
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1102824196 359 TLAIPKRITTLVRDIWQLQLRMSRRQGKRAW---KLMEHpKFRAAFDLLSLRAEIERNQELQ-RLAQW----WGEFQ 427
Cdd:COG0617 266 RLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQeRLAELleaaWRRFQ 341
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
62-193 |
8.47e-51 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 168.23 E-value: 8.47e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 62 AYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLV----GRRFRLAHVMFGPEIIEVATFRGHHeaGESDRTTS 137
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLFRRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEF--DESDFRNP 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1102824196 138 QRGQNGmllrdnifGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIR 193
Cdd:pfam01743 79 RSEEYT--------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
45-189 |
3.15e-43 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 148.90 E-value: 3.15e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 45 SENALKVLYRLNKA-GYEAYLVGGGVRDLLLGKKPKDFDVTTSA-TPEQVRKLFR--NCRLVGR--RFRLAHVMFGPEII 118
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1102824196 119 EVATFRGHHEAgesdrttsqrgQNGMLLRDNIFGsIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKD 189
Cdd:cd05398 81 DVATLRTETYT-----------DPGRRPPVVGFT-IEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
1-444 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 941.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 1 MFTRVANFCRKVLSREESMANDAIAQNRMSVIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 80
Cdd:PRK11623 8 IFTRVANFCRKVLSREESEAEQAVARPQMTVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 81 FDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEAGESDRTTSQRGQNGMLLRDNIFGSIEEDAQR 160
Cdd:PRK11623 88 FDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESDRNTSQRGQNGMLLRDNIFGSIEEDAQR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 161 RDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTPETRYREDPVRMLRAVRFAAKLSMRISPETAEPIPRLATLIND 240
Cdd:PRK11623 168 RDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLND 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 241 VPPARLFEEALKLLQAGYGYETYKLLREYSLFQPLFPTITRCFTENGDSPMERMIAQVLKNTDTRIHNDMRVNPAFLFAA 320
Cdd:PRK11623 248 IPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 321 MFWYPLLEAAQRIAQESGLAYYDAFALAANDVLDEACRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 400
Cdd:PRK11623 328 MFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 407
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1102824196 401 FDLLSLRAEIERNQELQRLAQWWGEFQVSAPPEQKDMLVDLDDE 444
Cdd:PRK11623 408 YDLLALRAEVENNAELQRLAQWWGEFQVSAPPQQKGMLNELDDD 451
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
31-437 |
2.92e-166 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 474.67 E-value: 2.92e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 31 VIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAH 110
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 111 VMFGPEIIEVATFRGHHEagesdrttSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDG 190
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGHK--------SSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 191 LIRLIGTPETRYREDPVRMLRAVRFAAKLSMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGYGYETYKLLREYS 270
Cdd:TIGR01942 153 RLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 271 LFQPLFPTITRCFTENGDSPMERMIAQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLEAAQRIAQEsGLAYYDAFALAAN 350
Cdd:TIGR01942 233 LLEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 351 DVLDEACRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAFDLLSLRAEIERnqELQRLAQWWGEFQVSA 430
Cdd:TIGR01942 312 DFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVCGR--ENAVLGEWWTPYQLAS 389
|
....*..
gi 1102824196 431 PPEQKDM 437
Cdd:TIGR01942 390 EEERTEM 396
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
43-427 |
1.18e-124 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 367.99 E-value: 1.18e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 43 DISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFR---NCRLVGRRFRLAHVMFGPEIIE 119
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 120 VATFRGHHEAGESDRTtsqrgqngmllrDNIFG-SIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTP 198
Cdd:COG0617 81 VATARTERYYGDGRRP------------FVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 199 ETRYREDPVRMLRAVRFAAKLSMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGYGYETYKLLREYSLFQPLfpt 278
Cdd:COG0617 149 EERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 279 itrcftengdspmermiaqvlkntdtrihndmrvnpAFLFAAMFwYPLLEAAQRiaqESGLAYYDAFALAANDVLDEACR 358
Cdd:COG0617 226 ------------------------------------ALRLAALL-HDLGKPATR---EDGLPTFHGHEEAGAELAEALLK 265
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1102824196 359 TLAIPKRITTLVRDIWQLQLRMSRRQGKRAW---KLMEHpKFRAAFDLLSLRAEIERNQELQ-RLAQW----WGEFQ 427
Cdd:COG0617 266 RLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQeRLAELleaaWRRFQ 341
|
|
| PRK13299 |
PRK13299 |
tRNA CCA-pyrophosphorylase; Provisional |
42-273 |
4.62e-52 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237339 [Multi-domain] Cd Length: 394 Bit Score: 180.42 E-value: 4.62e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 42 KDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVA 121
Cdd:PRK13299 3 PSEFQKALPILEKIKEAGFEAYFVGGSVRDYLLGRPIHDVDIATSAYPEEVKAIFPRTVDVGIEHGTVLVLENGEEYEVT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 122 TFRGhheagESDRTTSQRGQNGMLLRdnifgSIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRLIGTPETR 201
Cdd:PRK13299 83 TFRT-----ESEYVDYRRPSEVTFVR-----SLEEDLKRRDFTINAIAMD-ENGEIIDLFDGLEDLKNRLIRAVGNAEER 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1102824196 202 YREDPVRMLRAVRFAAKLSMRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGYGYETYKLLREYSLFQ 273
Cdd:PRK13299 152 FQEDALRMMRAVRFASQLGFDLETETFEAMKTQAPLLEKISVERIFVEFEKLLLGPFWRKGLKLLIETGLYN 223
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
62-193 |
8.47e-51 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 168.23 E-value: 8.47e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 62 AYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLV----GRRFRLAHVMFGPEIIEVATFRGHHeaGESDRTTS 137
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLFRRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEF--DESDFRNP 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1102824196 138 QRGQNGmllrdnifGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIR 193
Cdd:pfam01743 79 RSEEYT--------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| PolyA_pol_arg_C |
pfam12626 |
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is ... |
337-444 |
4.03e-45 |
|
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is arginine-rich and is necessary for full functioning of the enzyme.
Pssm-ID: 463647 [Multi-domain] Cd Length: 116 Bit Score: 153.13 E-value: 4.03e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 337 SGLAYYDAFALAANDVLDEACRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAFDLLSLRAEIErnQEL 416
Cdd:pfam12626 1 QGLPPYDALQLAADEVLDEQCQRVAIPRRFTAPMREIWLLQPRLEKRQGKRPFRLLEHPRFRAAYDFLLLRAESG--EVL 78
|
90 100
....*....|....*....|....*...
gi 1102824196 417 QRLAQWWGEFQVSAPPEQKDMLVDLDDE 444
Cdd:pfam12626 79 QELAEWWTRFQEADEAEREAMIAELGAD 106
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
45-189 |
3.15e-43 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 148.90 E-value: 3.15e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 45 SENALKVLYRLNKA-GYEAYLVGGGVRDLLLGKKPKDFDVTTSA-TPEQVRKLFR--NCRLVGR--RFRLAHVMFGPEII 118
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1102824196 119 EVATFRGHHEAgesdrttsqrgQNGMLLRDNIFGsIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKD 189
Cdd:cd05398 81 DVATLRTETYT-----------DPGRRPPVVGFT-IEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| PolyA_pol_RNAbd |
pfam12627 |
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA ... |
221-277 |
6.76e-18 |
|
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA and SrmB binding motifs on polymerase A.
Pssm-ID: 463648 [Multi-domain] Cd Length: 64 Bit Score: 77.52 E-value: 6.76e-18
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1102824196 221 MRISPETAEPIPRLATLINDVPPARLFEEALKLLQAGYGYETYKLLREYSLFQPLFP 277
Cdd:pfam12627 2 FTIEPETREAIRKLAPLLKKISPERIFEELLKLLLSGHPERGLELLRETGLLEYLFP 58
|
|
| cca |
PRK10885 |
multifunctional CCA addition/repair protein; |
63-229 |
2.11e-16 |
|
multifunctional CCA addition/repair protein;
Pssm-ID: 182810 [Multi-domain] Cd Length: 409 Bit Score: 80.67 E-value: 2.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 63 YLVGGGVRDLLLGKKPKDFD-VTTSATPEQVrkLFRNCRLVGRRFRlahVMFGPEIievatfrghHEAGESDRT--TSQR 139
Cdd:PRK10885 4 YLVGGAVRDALLGLPVKDRDwVVVGATPEEM--LAQGYQQVGKDFP---VFLHPKT---------HEEYALARTerKSGR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 140 GQNGMllrdnIFG-----SIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRLIGTPetrYREDPVRMLRAVR 214
Cdd:PRK10885 70 GYTGF-----TCYaapdvTLEEDLIRRDLTINAMAQD-DDGELIDPYGGQRDLEARLLRHVSPA---FAEDPLRVLRVAR 140
|
170
....*....|....*...
gi 1102824196 215 FAAK---LSMRISPETAE 229
Cdd:PRK10885 141 FAARfahLGFRIAPETLA 158
|
|
| PRK13297 |
PRK13297 |
tRNA CCA-pyrophosphorylase; Provisional |
58-256 |
5.82e-15 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 139469 [Multi-domain] Cd Length: 364 Bit Score: 76.19 E-value: 5.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 58 AGYEAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVRKlfRNCRLVGRRFRlahVMFGPEIIEvatfrgHHEAGESDRtT 136
Cdd:PRK13297 10 AGLQVYIVGGAVRDALLGLPAGDRDwVVVGATPEDMAR--RGFIPVGGDFP---VFLHPRTKE------EYALARTER-K 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 137 SQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVrDYVGGMQDLKDGLIRLIGTPetrYREDPVRMLRAVRFA 216
Cdd:PRK13297 78 SGRGYKGFTFYTGADVTLEQDLQRRDLTVNAIARTPQGELV-DPLDGVADVRARVLRHVGEA---FAEDPVRILRLGRFA 153
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1102824196 217 AKLS-MRISPETAEPIPRL--ATLINDVPPARLFEEALKLLQA 256
Cdd:PRK13297 154 ARFGdFSIAPETMQLCRRMveAGEADALVPERVWKEVSRGLMA 196
|
|
| PRK13298 |
PRK13298 |
tRNA CCA-pyrophosphorylase; Provisional |
61-227 |
1.15e-14 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237338 [Multi-domain] Cd Length: 417 Bit Score: 75.54 E-value: 1.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 61 EAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVrkLFRNCRLVGRRFRlahVMFGPEiievatfrgHHEAGESDRT--TS 137
Cdd:PRK13298 2 KIYLVGGAVRDSLLNLPVKDKDwVVVGGTPKIL--LSINFQQVGKDFP---VFLHPE---------THEEYALARTerKS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 138 QRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRLIGTPetrYREDPVRMLRAVRFAA 217
Cdd:PRK13298 68 GVGYTGFITDTSSDVTLEEDLIRRDLTINAIAQD-ENGNYIDPFQGKKDIQLRLLRHVSES---FIEDPLRVLRVARFAA 143
|
170
....*....|...
gi 1102824196 218 KLS---MRISPET 227
Cdd:PRK13298 144 LLVhlgFKIAKET 156
|
|
| PRK13296 |
PRK13296 |
CCA tRNA nucleotidyltransferase; |
61-311 |
1.25e-14 |
|
CCA tRNA nucleotidyltransferase;
Pssm-ID: 106256 [Multi-domain] Cd Length: 360 Bit Score: 75.02 E-value: 1.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 61 EAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVRKlfrncrlVGRRFRLAH--VMFGPEIIEvatfrgHHEAGESDRTTS 137
Cdd:PRK13296 2 KFYLVGGAVRDMLLGITPKDKDwVVVGATEDEMLA-------NGFIKIAANfpVFIHPQTKQ------EYALARSEKKTA 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 138 qRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRliGTPETrYREDPVRMLRAVRFAA 217
Cdd:PRK13296 69 -SGYHGFEVNFSKYITLEDDLKRRDLTINSIAID-QNNKVIDPFNGQADLQNRILR--HTSIA-FIEDPLRVVRLARFKA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 218 KLS---MRISPETAEPIPRLATL--INDVPPARLFEEALKLLQAGYGYetYKLLREYSLFQPLFPTIT--------RCFT 284
Cdd:PRK13296 144 QLSnfnFSIAQEMLALIKELVKTgeLNHLTRERLHIEFVKALNNPKIF--FTTLKELEALKIIFPNIScilplipnKSFF 221
|
250 260 270
....*....|....*....|....*....|
gi 1102824196 285 ENG---DSPMERMIAQVLKNTDTRIHNDMR 311
Cdd:PRK13296 222 ENPiykGSNINEKITLCLLKIPQQQLDDIR 251
|
|
| PHA01806 |
PHA01806 |
hypothetical protein |
29-218 |
2.96e-06 |
|
hypothetical protein
Pssm-ID: 222838 Cd Length: 200 Bit Score: 47.95 E-value: 2.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 29 MSVIPREQHnISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTT-SATPEQVRKLFrNCRLvgrrfr 107
Cdd:PHA01806 6 SDLLEGTKE-IPEGLIAKALLLRLYSDARHSEGVALAGGAARDLMHGAEPKDIDIALyGMDDRQAELLI-GCIL------ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1102824196 108 lahVMFGPEIIEVATFRG-HHEAGESDRTTSQ------RGQNGMLLRDNIF--GSIEEDAQRRDFTINSLyysVADFTVR 178
Cdd:PHA01806 78 ---PKLVSRFLRDGGWSQeYHDGGDGGIFKGVvslkgcRGLEGMDVDFNYYdtDSVGEVMESFDYTINQV---GIAYNWP 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1102824196 179 DYVGG-------MQDLKDGLIRligtpetRYREDPVRMLRAVRFAAK 218
Cdd:PHA01806 152 DPEGGprlgaylHKDVTWGVNK-------ELRAGSRLPERAEKMRAK 191
|
|
| |
