DNA helicase RecQ [Bifidobacterium animalis]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||||
| RecQ | COG0514 | Superfamily II DNA helicase RecQ [Replication, recombination and repair]; |
8-511 | 0e+00 | ||||||||
Superfamily II DNA helicase RecQ [Replication, recombination and repair]; : Pssm-ID: 440280 [Multi-domain] Cd Length: 489 Bit Score: 668.77 E-value: 0e+00
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| HRDC | pfam00570 | HRDC domain; The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic ... |
578-645 | 8.53e-22 | ||||||||
HRDC domain; The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding. Mutations in the HRDC domain cause human disease. It is interesting to note that the RecQ helicase in Deinococcus radiodurans has three tandem HRDC domains. : Pssm-ID: 425755 [Multi-domain] Cd Length: 68 Bit Score: 89.13 E-value: 8.53e-22
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| Name | Accession | Description | Interval | E-value | ||||||||||
| RecQ | COG0514 | Superfamily II DNA helicase RecQ [Replication, recombination and repair]; |
8-511 | 0e+00 | ||||||||||
Superfamily II DNA helicase RecQ [Replication, recombination and repair]; Pssm-ID: 440280 [Multi-domain] Cd Length: 489 Bit Score: 668.77 E-value: 0e+00
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| recQ | TIGR01389 | ATP-dependent DNA helicase RecQ; The ATP-dependent DNA helicase RecQ of E. coli is about 600 ... |
13-646 | 0e+00 | ||||||||||
ATP-dependent DNA helicase RecQ; The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273594 [Multi-domain] Cd Length: 591 Bit Score: 649.06 E-value: 0e+00
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| PRK11057 | PRK11057 | ATP-dependent DNA helicase RecQ; Provisional |
7-646 | 1.31e-169 | ||||||||||
ATP-dependent DNA helicase RecQ; Provisional Pssm-ID: 182933 [Multi-domain] Cd Length: 607 Bit Score: 497.70 E-value: 1.31e-169
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| DEXHc_RecQ | cd17920 | DEXH-box helicase domain of RecQ family proteins; The RecQ family of the type II DEAD box ... |
11-207 | 1.89e-92 | ||||||||||
DEXH-box helicase domain of RecQ family proteins; The RecQ family of the type II DEAD box helicase superfamily is a family of highly conserved DNA repair helicases. This domain contains the ATP-binding region. Pssm-ID: 350678 [Multi-domain] Cd Length: 200 Bit Score: 284.43 E-value: 1.89e-92
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| DpdF | NF041063 | protein DpdF; |
14-365 | 5.69e-46 | ||||||||||
protein DpdF; Pssm-ID: 468990 [Multi-domain] Cd Length: 813 Bit Score: 174.71 E-value: 5.69e-46
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| DEAD | pfam00270 | DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
24-162 | 1.59e-25 | ||||||||||
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression. Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 103.09 E-value: 1.59e-25
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| HRDC | pfam00570 | HRDC domain; The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic ... |
578-645 | 8.53e-22 | ||||||||||
HRDC domain; The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding. Mutations in the HRDC domain cause human disease. It is interesting to note that the RecQ helicase in Deinococcus radiodurans has three tandem HRDC domains. Pssm-ID: 425755 [Multi-domain] Cd Length: 68 Bit Score: 89.13 E-value: 8.53e-22
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| DEXDc | smart00487 | DEAD-like helicases superfamily; |
16-166 | 2.11e-21 | ||||||||||
DEAD-like helicases superfamily; Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 92.55 E-value: 2.11e-21
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| HRDC | smart00341 | Helicase and RNase D C-terminal; Hypothetical role in nucleic acid binding. Mutations in the ... |
580-648 | 1.65e-17 | ||||||||||
Helicase and RNase D C-terminal; Hypothetical role in nucleic acid binding. Mutations in the HRDC domain cause human disease. Pssm-ID: 128635 [Multi-domain] Cd Length: 81 Bit Score: 77.34 E-value: 1.65e-17
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| Rnd | COG0349 | Ribonuclease D [Translation, ribosomal structure and biogenesis]; |
585-646 | 5.36e-07 | ||||||||||
Ribonuclease D [Translation, ribosomal structure and biogenesis]; Pssm-ID: 440118 [Multi-domain] Cd Length: 365 Bit Score: 52.18 E-value: 5.36e-07
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| Name | Accession | Description | Interval | E-value | ||||||||||
| RecQ | COG0514 | Superfamily II DNA helicase RecQ [Replication, recombination and repair]; |
8-511 | 0e+00 | ||||||||||
Superfamily II DNA helicase RecQ [Replication, recombination and repair]; Pssm-ID: 440280 [Multi-domain] Cd Length: 489 Bit Score: 668.77 E-value: 0e+00
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| recQ | TIGR01389 | ATP-dependent DNA helicase RecQ; The ATP-dependent DNA helicase RecQ of E. coli is about 600 ... |
13-646 | 0e+00 | ||||||||||
ATP-dependent DNA helicase RecQ; The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273594 [Multi-domain] Cd Length: 591 Bit Score: 649.06 E-value: 0e+00
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| PRK11057 | PRK11057 | ATP-dependent DNA helicase RecQ; Provisional |
7-646 | 1.31e-169 | ||||||||||
ATP-dependent DNA helicase RecQ; Provisional Pssm-ID: 182933 [Multi-domain] Cd Length: 607 Bit Score: 497.70 E-value: 1.31e-169
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| recQ_fam | TIGR00614 | ATP-dependent DNA helicase, RecQ family; All proteins in this family for which functions are ... |
14-490 | 8.46e-149 | ||||||||||
ATP-dependent DNA helicase, RecQ family; All proteins in this family for which functions are known are 3'-5' DNA-DNA helicases. These proteins are used for recombination, recombinational repair, and possibly maintenance of chromosome stability. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 129701 [Multi-domain] Cd Length: 470 Bit Score: 439.21 E-value: 8.46e-149
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| PLN03137 | PLN03137 | ATP-dependent DNA helicase; Q4-like; Provisional |
15-645 | 6.31e-103 | ||||||||||
ATP-dependent DNA helicase; Q4-like; Provisional Pssm-ID: 215597 [Multi-domain] Cd Length: 1195 Bit Score: 339.18 E-value: 6.31e-103
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| DEXHc_RecQ | cd17920 | DEXH-box helicase domain of RecQ family proteins; The RecQ family of the type II DEAD box ... |
11-207 | 1.89e-92 | ||||||||||
DEXH-box helicase domain of RecQ family proteins; The RecQ family of the type II DEAD box helicase superfamily is a family of highly conserved DNA repair helicases. This domain contains the ATP-binding region. Pssm-ID: 350678 [Multi-domain] Cd Length: 200 Bit Score: 284.43 E-value: 1.89e-92
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| DEXHc_RecQ4-like | cd18018 | DEAH-box helicase domain of RecQ4 and similar proteins; ATP-dependent DNA helicase Q4 (RecQ4) ... |
11-207 | 3.20e-68 | ||||||||||
DEAH-box helicase domain of RecQ4 and similar proteins; ATP-dependent DNA helicase Q4 (RecQ4) is part of the RecQ family of highly conserved DNA repair helicases that is part of the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region. Mutations cause Rothmund-Thomson/RAPADILINO/Baller-Gerold syndrome. Pssm-ID: 350776 [Multi-domain] Cd Length: 201 Bit Score: 220.98 E-value: 3.20e-68
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| DEXHc_RecQ3 | cd18017 | DEAH-box helicase domain of RecQ3; DEAD-like helicase RecQ3 (also called Werner syndrome ... |
11-207 | 1.84e-60 | ||||||||||
DEAH-box helicase domain of RecQ3; DEAD-like helicase RecQ3 (also called Werner syndrome ATP-dependent helicase or WRN) is part of the RecQ family of highly conserved DNA repair helicases that is part of the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region. Mutations cause Werner's syndrome. Pssm-ID: 350775 [Multi-domain] Cd Length: 193 Bit Score: 200.39 E-value: 1.84e-60
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| SF2_C_RecQ | cd18794 | C-terminal helicase domain of the RecQ family helicases; The RecQ helicase family is an ... |
208-354 | 1.96e-52 | ||||||||||
C-terminal helicase domain of the RecQ family helicases; The RecQ helicase family is an evolutionarily conserved class of enzymes, dedicated to preserving genomic integrity by operating in telomere maintenance, DNA repair, and replication. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350181 [Multi-domain] Cd Length: 134 Bit Score: 176.63 E-value: 1.96e-52
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| DEXHc_RecQ1 | cd18015 | DEXH-box helicase domain of RecQ1; ATP-dependent DNA helicase Q1 (RecQ1) is part of the RecQ ... |
12-207 | 2.16e-52 | ||||||||||
DEXH-box helicase domain of RecQ1; ATP-dependent DNA helicase Q1 (RecQ1) is part of the RecQ family of highly conserved DNA repair helicases that is part of the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region. Pssm-ID: 350773 [Multi-domain] Cd Length: 209 Bit Score: 179.48 E-value: 2.16e-52
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| DEXHc_RecQ5 | cd18014 | DEAH-box helicase domain of RecQ5; ATP-dependent DNA helicase Q5 (RecQ5) is part of the RecQ ... |
11-202 | 2.67e-47 | ||||||||||
DEAH-box helicase domain of RecQ5; ATP-dependent DNA helicase Q5 (RecQ5) is part of the RecQ family of highly conserved DNA repair helicases that is part of the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region. Pssm-ID: 350772 [Multi-domain] Cd Length: 205 Bit Score: 165.34 E-value: 2.67e-47
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| DEXHc_RecQ2_BLM | cd18016 | DEAH-box helicase domain of RecQ2; ATP-dependent DNA helicase Q2 (RecQ2, also called Bloom ... |
11-207 | 3.16e-46 | ||||||||||
DEAH-box helicase domain of RecQ2; ATP-dependent DNA helicase Q2 (RecQ2, also called Bloom syndrome protein homolog or BLM) is part of the RecQ family of highly conserved DNA repair helicases that is part of the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region. Mutations in RecQ2 cause Bloom syndrome. Pssm-ID: 350774 [Multi-domain] Cd Length: 208 Bit Score: 162.69 E-value: 3.16e-46
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| DpdF | NF041063 | protein DpdF; |
14-365 | 5.69e-46 | ||||||||||
protein DpdF; Pssm-ID: 468990 [Multi-domain] Cd Length: 813 Bit Score: 174.71 E-value: 5.69e-46
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| DEAD | pfam00270 | DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
24-162 | 1.59e-25 | ||||||||||
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression. Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 103.09 E-value: 1.59e-25
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| RQC | pfam09382 | RQC domain; This DNA-binding domain is found in the RecQ helicase among others and has a ... |
436-530 | 6.44e-22 | ||||||||||
RQC domain; This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain. Pssm-ID: 462780 [Multi-domain] Cd Length: 108 Bit Score: 91.06 E-value: 6.44e-22
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| HRDC | pfam00570 | HRDC domain; The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic ... |
578-645 | 8.53e-22 | ||||||||||
HRDC domain; The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding. Mutations in the HRDC domain cause human disease. It is interesting to note that the RecQ helicase in Deinococcus radiodurans has three tandem HRDC domains. Pssm-ID: 425755 [Multi-domain] Cd Length: 68 Bit Score: 89.13 E-value: 8.53e-22
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| DEXDc | smart00487 | DEAD-like helicases superfamily; |
16-166 | 2.11e-21 | ||||||||||
DEAD-like helicases superfamily; Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 92.55 E-value: 2.11e-21
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| Helicase_C | pfam00271 | Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
222-345 | 3.96e-21 | ||||||||||
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase. Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 88.81 E-value: 3.96e-21
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| RQC | smart00956 | This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix ... |
441-530 | 4.41e-20 | ||||||||||
This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain. Pssm-ID: 214936 [Multi-domain] Cd Length: 92 Bit Score: 85.22 E-value: 4.41e-20
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| HELICc | smart00490 | helicase superfamily c-terminal domain; |
277-345 | 2.76e-19 | ||||||||||
helicase superfamily c-terminal domain; Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 82.64 E-value: 2.76e-19
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| HRDC | smart00341 | Helicase and RNase D C-terminal; Hypothetical role in nucleic acid binding. Mutations in the ... |
580-648 | 1.65e-17 | ||||||||||
Helicase and RNase D C-terminal; Hypothetical role in nucleic acid binding. Mutations in the HRDC domain cause human disease. Pssm-ID: 128635 [Multi-domain] Cd Length: 81 Bit Score: 77.34 E-value: 1.65e-17
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| SF2_C_DEAD | cd18787 | C-terminal helicase domain of the DEAD box helicases; DEAD-box helicases comprise a diverse ... |
223-353 | 3.30e-16 | ||||||||||
C-terminal helicase domain of the DEAD box helicases; DEAD-box helicases comprise a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis, and RNA degradation. They are superfamily (SF)2 helicases that, similar to SF1, do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350174 [Multi-domain] Cd Length: 131 Bit Score: 75.62 E-value: 3.30e-16
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| SrmB | COG0513 | Superfamily II DNA and RNA helicase [Replication, recombination and repair]; |
10-346 | 6.35e-16 | ||||||||||
Superfamily II DNA and RNA helicase [Replication, recombination and repair]; Pssm-ID: 440279 [Multi-domain] Cd Length: 420 Bit Score: 80.19 E-value: 6.35e-16
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| YprA | COG1205 | ATP-dependent helicase YprA, contains C-terminal metal-binding DUF1998 domain [Replication, ... |
27-348 | 1.46e-15 | ||||||||||
ATP-dependent helicase YprA, contains C-terminal metal-binding DUF1998 domain [Replication, recombination and repair]; Pssm-ID: 440818 [Multi-domain] Cd Length: 758 Bit Score: 80.26 E-value: 1.46e-15
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| SF2_C_Hrq | cd18797 | C-terminal helicase domain of HrQ family helicases; Yeast Hrq1, similar to RecQ4, plays a role ... |
217-348 | 7.09e-15 | ||||||||||
C-terminal helicase domain of HrQ family helicases; Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. HrQ family helicases are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350184 [Multi-domain] Cd Length: 146 Bit Score: 72.29 E-value: 7.09e-15
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| PLN00206 | PLN00206 | DEAD-box ATP-dependent RNA helicase; Provisional |
19-358 | 3.55e-14 | ||||||||||
DEAD-box ATP-dependent RNA helicase; Provisional Pssm-ID: 215103 [Multi-domain] Cd Length: 518 Bit Score: 75.59 E-value: 3.55e-14
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| RecQ_Zn_bind | pfam16124 | RecQ zinc-binding; This domain is the zinc-binding domain of ATP-dependent DNA helicase RecQ. |
357-433 | 3.09e-12 | ||||||||||
RecQ zinc-binding; This domain is the zinc-binding domain of ATP-dependent DNA helicase RecQ. Pssm-ID: 465031 [Multi-domain] Cd Length: 66 Bit Score: 61.92 E-value: 3.09e-12
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| SF2-N | cd00046 | N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
37-172 | 1.37e-10 | ||||||||||
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region. Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 59.72 E-value: 1.37e-10
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| SSL2 | COG1061 | Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
24-395 | 2.61e-10 | ||||||||||
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 63.51 E-value: 2.61e-10
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| SF2_C_LHR | cd18796 | C-terminal helicase domain of LHR family helicases; Large helicase-related protein (LHR) is a ... |
227-349 | 5.30e-09 | ||||||||||
C-terminal helicase domain of LHR family helicases; Large helicase-related protein (LHR) is a DNA damage-inducible helicase that uses ATP hydrolysis to drive unidirectional 3'-to-5' translocation along single-stranded DNA (ssDNA) and to unwind RNA:DNA duplexes. This group also includes related bacterial and archaeal helicases. LHR family helicases are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350183 [Multi-domain] Cd Length: 150 Bit Score: 55.35 E-value: 5.30e-09
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| BRR2 | COG1204 | Replicative superfamily II helicase [Replication, recombination and repair]; |
18-408 | 6.57e-09 | ||||||||||
Replicative superfamily II helicase [Replication, recombination and repair]; Pssm-ID: 440817 [Multi-domain] Cd Length: 529 Bit Score: 58.75 E-value: 6.57e-09
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| DEXHc_Hrq1-like | cd17923 | DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a ... |
27-146 | 7.45e-09 | ||||||||||
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. Hrq1 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region. Pssm-ID: 350681 [Multi-domain] Cd Length: 182 Bit Score: 55.67 E-value: 7.45e-09
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| PRK11634 | PRK11634 | ATP-dependent RNA helicase DeaD; Provisional |
19-382 | 1.71e-07 | ||||||||||
ATP-dependent RNA helicase DeaD; Provisional Pssm-ID: 236941 [Multi-domain] Cd Length: 629 Bit Score: 54.47 E-value: 1.71e-07
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| PTZ00424 | PTZ00424 | helicase 45; Provisional |
240-345 | 1.83e-07 | ||||||||||
helicase 45; Provisional Pssm-ID: 185609 [Multi-domain] Cd Length: 401 Bit Score: 53.68 E-value: 1.83e-07
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| SF2_C | cd18785 | C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases ... |
303-353 | 3.21e-07 | ||||||||||
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases include DEAD-box helicases, UvrB, RecG, Ski2, Sucrose Non-Fermenting (SNF) family helicases, and dicer proteins, among others. Similar to SF1 helicases, they do not form toroidal structures like SF3-6 helicases. SF2 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350172 [Multi-domain] Cd Length: 77 Bit Score: 48.08 E-value: 3.21e-07
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| PTZ00110 | PTZ00110 | helicase; Provisional |
240-345 | 4.50e-07 | ||||||||||
helicase; Provisional Pssm-ID: 240273 [Multi-domain] Cd Length: 545 Bit Score: 52.85 E-value: 4.50e-07
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| Rnd | COG0349 | Ribonuclease D [Translation, ribosomal structure and biogenesis]; |
585-646 | 5.36e-07 | ||||||||||
Ribonuclease D [Translation, ribosomal structure and biogenesis]; Pssm-ID: 440118 [Multi-domain] Cd Length: 365 Bit Score: 52.18 E-value: 5.36e-07
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| DEADc_DDX46 | cd17953 | DEAD-box helicase domain of DEAD box protein 46; DDX46 (also called Prp5-like DEAD-box protein) ... |
16-59 | 1.85e-06 | ||||||||||
DEAD-box helicase domain of DEAD box protein 46; DDX46 (also called Prp5-like DEAD-box protein) is a component of the 17S U2 snRNP complex. It plays an important role in pre-mRNA splicing and has a role in antiviral innate immunity. DDX46 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350711 [Multi-domain] Cd Length: 222 Bit Score: 49.30 E-value: 1.85e-06
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| DEADc | cd00268 | DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family ... |
11-59 | 1.96e-06 | ||||||||||
DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350669 [Multi-domain] Cd Length: 196 Bit Score: 48.98 E-value: 1.96e-06
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| PRK11192 | PRK11192 | ATP-dependent RNA helicase SrmB; Provisional |
237-345 | 2.26e-06 | ||||||||||
ATP-dependent RNA helicase SrmB; Provisional Pssm-ID: 236877 [Multi-domain] Cd Length: 434 Bit Score: 50.33 E-value: 2.26e-06
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| SF2_C_Ski2 | cd18795 | C-terminal helicase domain of the Ski2 family helicases; Ski2-like RNA helicases play an ... |
199-345 | 2.61e-06 | ||||||||||
C-terminal helicase domain of the Ski2 family helicases; Ski2-like RNA helicases play an important role in RNA degradation, processing, and splicing pathways. This family includes spliceosomal Brr2 RNA helicase, ASCC3 (involved in the repair of N-alkylated nucleotides), Mtr4 (involved in processing of structured RNAs), DDX60 (involved in viral RNA degradation), and other proteins. Ski2-like RNA helicases are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350182 [Multi-domain] Cd Length: 154 Bit Score: 47.55 E-value: 2.61e-06
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| DEADc_DDX49 | cd17955 | DEAD-box helicase domain of DEAD box protein 49; DDX49 (also called Dbp8) is a member of the ... |
8-64 | 8.92e-06 | ||||||||||
DEAD-box helicase domain of DEAD box protein 49; DDX49 (also called Dbp8) is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350713 [Multi-domain] Cd Length: 204 Bit Score: 46.83 E-value: 8.92e-06
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| DEADc_DDX18 | cd17942 | DEAD-box helicase domain of DEAD box protein 18; This DDX18 gene encodes a DEAD box protein ... |
16-70 | 1.62e-05 | ||||||||||
DEAD-box helicase domain of DEAD box protein 18; This DDX18 gene encodes a DEAD box protein and is activated by Myc protein. DDX18 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350700 [Multi-domain] Cd Length: 198 Bit Score: 46.20 E-value: 1.62e-05
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| PRK10590 | PRK10590 | ATP-dependent RNA helicase RhlE; Provisional |
240-343 | 2.64e-05 | ||||||||||
ATP-dependent RNA helicase RhlE; Provisional Pssm-ID: 236722 [Multi-domain] Cd Length: 456 Bit Score: 47.11 E-value: 2.64e-05
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| DEADc_DDX52 | cd17957 | DEAD-box helicase domain of DEAD box protein 52; DDX52 (also called ROK1 and HUSSY19) is ... |
25-70 | 3.16e-05 | ||||||||||
DEAD-box helicase domain of DEAD box protein 52; DDX52 (also called ROK1 and HUSSY19) is ubiquitously expressed in testis, endometrium, and other tissues in humans. DDX52 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350715 [Multi-domain] Cd Length: 198 Bit Score: 45.27 E-value: 3.16e-05
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| PRK11192 | PRK11192 | ATP-dependent RNA helicase SrmB; Provisional |
11-59 | 9.39e-05 | ||||||||||
ATP-dependent RNA helicase SrmB; Provisional Pssm-ID: 236877 [Multi-domain] Cd Length: 434 Bit Score: 45.32 E-value: 9.39e-05
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| DEADc_DDX42 | cd17952 | DEAD-box helicase domain of DEAD box protein 42; DDX42 (also called Splicing Factor ... |
19-59 | 1.04e-04 | ||||||||||
DEAD-box helicase domain of DEAD box protein 42; DDX42 (also called Splicing Factor 3B-Associated 125 kDa Protein, RHELP, or RNAHP) is an NTPase with a preference for ATP, the hydrolysis of which is enhanced by various RNA substrates. It acts as a non-processive RNA helicase with protein displacement and RNA annealing activities. DDX42 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350710 [Multi-domain] Cd Length: 197 Bit Score: 43.94 E-value: 1.04e-04
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| DEADc_DDX54 | cd17959 | DEAD-box helicase domain of DEAD box protein 54; DDX54 interacts in a hormone-dependent manner ... |
19-57 | 1.57e-04 | ||||||||||
DEAD-box helicase domain of DEAD box protein 54; DDX54 interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. DDX54 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350717 [Multi-domain] Cd Length: 205 Bit Score: 43.45 E-value: 1.57e-04
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| DEADc_DDX10 | cd17941 | DEAD-box helicase domain of DEAD box protein 10; Fusion of the DDX10 gene and the nucleoporin ... |
19-70 | 1.69e-04 | ||||||||||
DEAD-box helicase domain of DEAD box protein 10; Fusion of the DDX10 gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies. Diseases associated with DDX10 (also known as DDX10-NUP98 Fusion Protein Type 2) include myelodysplastic syndrome and leukemia, acute myeloid. DDX10 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350699 [Multi-domain] Cd Length: 198 Bit Score: 43.05 E-value: 1.69e-04
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| PRK01297 | PRK01297 | ATP-dependent RNA helicase RhlB; Provisional |
262-345 | 1.75e-04 | ||||||||||
ATP-dependent RNA helicase RhlB; Provisional Pssm-ID: 234938 [Multi-domain] Cd Length: 475 Bit Score: 44.52 E-value: 1.75e-04
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| SF2_C_RecG_TRCF | cd18792 | C-terminal helicase domain of the RecG family helicases; The DEAD-like helicase RecG family ... |
228-370 | 2.97e-04 | ||||||||||
C-terminal helicase domain of the RecG family helicases; The DEAD-like helicase RecG family contains recombination factor RecG and transcription-repair coupling factor TrcF. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350179 [Multi-domain] Cd Length: 160 Bit Score: 41.87 E-value: 2.97e-04
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| SF2_C_RecG | cd18811 | C-terminal helicase domain of DNA helicase RecG; ATP-dependent DNA helicase RecG plays a ... |
281-370 | 3.90e-04 | ||||||||||
C-terminal helicase domain of DNA helicase RecG; ATP-dependent DNA helicase RecG plays a critical role in recombination and DNA repair. RecG helps process Holliday junction intermediates to mature products by catalyzing branch migration. It is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC. Pssm-ID: 350198 [Multi-domain] Cd Length: 159 Bit Score: 41.56 E-value: 3.90e-04
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| DEXHc_archSki2 | cd18028 | DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play ... |
22-74 | 4.27e-04 | ||||||||||
DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play an important role in RNA degradation, processing and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region. Pssm-ID: 350786 [Multi-domain] Cd Length: 177 Bit Score: 41.55 E-value: 4.27e-04
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| DEADc_DDX47 | cd17954 | DEAD-box helicase domain of DEAD box protein 47; DDX47 (also called E4-DEAD box protein) can ... |
16-62 | 5.55e-04 | ||||||||||
DEAD-box helicase domain of DEAD box protein 47; DDX47 (also called E4-DEAD box protein) can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. DX47 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350712 [Multi-domain] Cd Length: 203 Bit Score: 41.53 E-value: 5.55e-04
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| COG1202 | COG1202 | Superfamily II helicase, archaea-specific [Replication, recombination and repair]; |
221-343 | 5.82e-04 | ||||||||||
Superfamily II helicase, archaea-specific [Replication, recombination and repair]; Pssm-ID: 440815 [Multi-domain] Cd Length: 790 Bit Score: 42.96 E-value: 5.82e-04
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| DEADc_DDX23 | cd17945 | DEAD-box helicase domain of DEAD box protein 23; DDX23 (also called U5 snRNP 100kD protein and ... |
19-59 | 8.14e-04 | ||||||||||
DEAD-box helicase domain of DEAD box protein 23; DDX23 (also called U5 snRNP 100kD protein and PRP28 homolog) is involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation. Diseases associated with DDX23 include distal hereditary motor neuropathy, type II. DDX23 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350703 [Multi-domain] Cd Length: 220 Bit Score: 41.15 E-value: 8.14e-04
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| DEADc_DDX51 | cd17956 | DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by ... |
11-57 | 9.05e-04 | ||||||||||
DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by regulating multiple signalling pathways. Mammalian DEAD box protein Ddx51 acts in 3' end maturation of 28S rRNA by promoting the release of U8 snoRNA.It is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350714 [Multi-domain] Cd Length: 231 Bit Score: 41.46 E-value: 9.05e-04
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| Lhr | COG1201 | Lhr-like helicase [Replication, recombination and repair]; |
1-77 | 1.28e-03 | ||||||||||
Lhr-like helicase [Replication, recombination and repair]; Pssm-ID: 440814 [Multi-domain] Cd Length: 850 Bit Score: 42.01 E-value: 1.28e-03
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| DinG | COG1199 | Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
9-69 | 1.54e-03 | ||||||||||
Rad3-related DNA helicase DinG [Replication, recombination and repair]; Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 41.45 E-value: 1.54e-03
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| PRK09751 | PRK09751 | putative ATP-dependent helicase Lhr; Provisional |
269-377 | 1.70e-03 | ||||||||||
putative ATP-dependent helicase Lhr; Provisional Pssm-ID: 137505 [Multi-domain] Cd Length: 1490 Bit Score: 41.83 E-value: 1.70e-03
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| Dob10 | COG4581 | Superfamily II RNA helicase [Replication, recombination and repair]; |
244-345 | 2.28e-03 | ||||||||||
Superfamily II RNA helicase [Replication, recombination and repair]; Pssm-ID: 443638 [Multi-domain] Cd Length: 751 Bit Score: 41.08 E-value: 2.28e-03
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| DEADc_DDX56 | cd17961 | DEAD-box helicase domain of DEAD box protein 56; DDX56 is a helicase required for assembly of ... |
9-64 | 2.35e-03 | ||||||||||
DEAD-box helicase domain of DEAD box protein 56; DDX56 is a helicase required for assembly of infectious West Nile virus particles. New research suggests that DDX56 relocalizes to the site of virus assembly during WNV infection and that its interaction with WNV capsid in the cytoplasm may occur transiently during virion morphogenesis. DDX56 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350719 [Multi-domain] Cd Length: 206 Bit Score: 39.87 E-value: 2.35e-03
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| DEADc_DDX24 | cd17946 | DEAD-box helicase domain of DEAD box protein 24; The human DDX24 gene encodes a DEAD box ... |
27-64 | 2.35e-03 | ||||||||||
DEAD-box helicase domain of DEAD box protein 24; The human DDX24 gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24. DDX24 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP- binding region. Pssm-ID: 350704 [Multi-domain] Cd Length: 235 Bit Score: 39.91 E-value: 2.35e-03
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| DEADc_DDX27 | cd17947 | DEAD-box helicase domain of DEAD box protein 27; DDX27 (also called RHLP, deficiency of ... |
10-59 | 3.15e-03 | ||||||||||
DEAD-box helicase domain of DEAD box protein 27; DDX27 (also called RHLP, deficiency of ribosomal subunits protein 1 homolog, and probable ATP-dependent RNA helicase DDX27) is involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. DDX27 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350705 [Multi-domain] Cd Length: 196 Bit Score: 39.16 E-value: 3.15e-03
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| DEADc_DDX41 | cd17951 | DEAD-box helicase domain of DEAD box protein 41; DDX41 (also called ABS and MPLPF) interacts ... |
25-60 | 3.52e-03 | ||||||||||
DEAD-box helicase domain of DEAD box protein 41; DDX41 (also called ABS and MPLPF) interacts with several spliceosomal proteins and may recognize the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response. Diseases associated with DDX41 include "myeloproliferative/lymphoproliferative neoplasms, familial" and "Ddx41-related susceptibility to familial myeloproliferative/lymphoproliferative neoplasms". DDX41 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350709 [Multi-domain] Cd Length: 206 Bit Score: 39.24 E-value: 3.52e-03
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| ResIII | pfam04851 | Type III restriction enzyme, res subunit; |
22-146 | 5.40e-03 | ||||||||||
Type III restriction enzyme, res subunit; Pssm-ID: 398492 [Multi-domain] Cd Length: 162 Bit Score: 38.04 E-value: 5.40e-03
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| DUF3106 | pfam11304 | Protein of unknown function (DUF3106); Some members in this family of proteins are annotated ... |
354-385 | 5.61e-03 | ||||||||||
Protein of unknown function (DUF3106); Some members in this family of proteins are annotated as transmembrane proteins however this cannot be confirmed. Currently no function is known. Pssm-ID: 463257 [Multi-domain] Cd Length: 104 Bit Score: 36.81 E-value: 5.61e-03
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| DEADc_DDX1 | cd17938 | DEAD-box helicase domain of DEAD box protein 1; DEAD box protein 1 (DDX1) acts as an ... |
27-59 | 8.69e-03 | ||||||||||
DEAD-box helicase domain of DEAD box protein 1; DEAD box protein 1 (DDX1) acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. It possesses 5' single-stranded RNA overhang nuclease activity as well as ATPase activity on various RNA, but not DNA polynucleotides. DDX1 may play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. It may also be involved in 3'-end cleavage and polyadenylation of pre-mRNAs. DDX1 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350696 [Multi-domain] Cd Length: 204 Bit Score: 38.07 E-value: 8.69e-03
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| DEADc_DDX4 | cd18052 | DEAD-box helicase domain of DEAD box protein 4; DEAD box protein 4 (DDX4, also known as VASA ... |
11-65 | 8.93e-03 | ||||||||||
DEAD-box helicase domain of DEAD box protein 4; DEAD box protein 4 (DDX4, also known as VASA homolog) is an ATP-dependent RNA helicase required during spermatogenesis and is essential for the germline integrity. DEAD-box helicases are a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region. Pssm-ID: 350810 [Multi-domain] Cd Length: 264 Bit Score: 38.41 E-value: 8.93e-03
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