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Conserved domains on  [gi|890833968|ref|WP_048903403|]
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MULTISPECIES: NADH-quinone oxidoreductase subunit NuoK [Pedobacter]

Protein Classification

NADH-quinone oxidoreductase subunit NuoK( domain architecture ID 10002232)

NADH-quinone oxidoreductase subunit K (NuoK) is part of the membrane domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

CATH:  1.10.287.3510
EC:  7.1.1.-
Gene Ontology:  GO:0048038|GO:0050136|GO:0042773
PubMed:  24059520|10940377|1470679

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 11-109 1.98e-43

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


:

Pssm-ID: 440477  Cd Length: 99  Bit Score: 136.73  E-value: 1.98e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  11 VPLNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIV 90
Cdd:COG0713    1 IPLEHYLILAAILFAIGLYGVLTRRNLIVVLMSIELMLNAVNLNLVAFSRYLGDLDGQVFALFVIAVAAAEVAVGLAIIV 80

                         90
                 ....*....|....*....
gi 890833968  91 MVYRNTQSVDINVLNRLKW 109
Cdd:COG0713   81 ALYRNRGTIDVDDLNELKG 99
 
Name Accession Description Interval E-value
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 11-109 1.98e-43

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 136.73  E-value: 1.98e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  11 VPLNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIV 90
Cdd:COG0713    1 IPLEHYLILAAILFAIGLYGVLTRRNLIVVLMSIELMLNAVNLNLVAFSRYLGDLDGQVFALFVIAVAAAEVAVGLAIIV 80

                         90
                 ....*....|....*....
gi 890833968  91 MVYRNTQSVDINVLNRLKW 109
Cdd:COG0713   81 ALYRNRGTIDVDDLNELKG 99
PRK05715 PRK05715
NADH-quinone oxidoreductase subunit NuoK;
11-109 3.63e-39

NADH-quinone oxidoreductase subunit NuoK;


Pssm-ID: 180218  Cd Length: 100  Bit Score: 126.06  E-value: 3.63e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  11 VPLNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIV 90
Cdd:PRK05715   2 IPLQHYLILAAILFCIGLVGLLLRRNAIVVLMSIELMLNAVNLNFVAFSSYLGDLDGQVFAFFVITVAAAEAAIGLAILL 81

                         90
                 ....*....|....*....
gi 890833968  91 MVYRNTQSVDINVLNRLKW 109
Cdd:PRK05715  82 QLYRNRGTIDVDDLNELKG 100
F420_dehyd_FpoK NF040614
F420H2 dehydrogenase subunit FpoK;
12-109 5.52e-30

F420H2 dehydrogenase subunit FpoK;


Pssm-ID: 468586  Cd Length: 98  Bit Score: 102.85  E-value: 5.52e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  12 PLNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVM 91
Cdd:NF040614   1 PLELYLGLAAIIFSIGLYGFMTQKNGIRLLMCVELMLNSANINLVAFSSYNDDLTGQVFALFSIALAAAEAAIGFAILMA 80

                         90
                 ....*....|....*...
gi 890833968  92 VYRNTQSVDINVLNRLKW 109
Cdd:NF040614  81 IYRMRDTINLDNINILRW 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
15-109 4.20e-26

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 93.01  E-value: 4.20e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968   15 HYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVMVYR 94
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYR 80

                          90
                  ....*....|....*
gi 890833968   95 NTQSVDINVLNRLKW 109
Cdd:pfam00420  81 THGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 11-109 1.98e-43

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 136.73  E-value: 1.98e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  11 VPLNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIV 90
Cdd:COG0713    1 IPLEHYLILAAILFAIGLYGVLTRRNLIVVLMSIELMLNAVNLNLVAFSRYLGDLDGQVFALFVIAVAAAEVAVGLAIIV 80

                         90
                 ....*....|....*....
gi 890833968  91 MVYRNTQSVDINVLNRLKW 109
Cdd:COG0713   81 ALYRNRGTIDVDDLNELKG 99
PRK05715 PRK05715
NADH-quinone oxidoreductase subunit NuoK;
11-109 3.63e-39

NADH-quinone oxidoreductase subunit NuoK;


Pssm-ID: 180218  Cd Length: 100  Bit Score: 126.06  E-value: 3.63e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  11 VPLNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIV 90
Cdd:PRK05715   2 IPLQHYLILAAILFCIGLVGLLLRRNAIVVLMSIELMLNAVNLNFVAFSSYLGDLDGQVFAFFVITVAAAEAAIGLAILL 81

                         90
                 ....*....|....*....
gi 890833968  91 MVYRNTQSVDINVLNRLKW 109
Cdd:PRK05715  82 QLYRNRGTIDVDDLNELKG 100
F420_dehyd_FpoK NF040614
F420H2 dehydrogenase subunit FpoK;
12-109 5.52e-30

F420H2 dehydrogenase subunit FpoK;


Pssm-ID: 468586  Cd Length: 98  Bit Score: 102.85  E-value: 5.52e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  12 PLNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVM 91
Cdd:NF040614   1 PLELYLGLAAIIFSIGLYGFMTQKNGIRLLMCVELMLNSANINLVAFSSYNDDLTGQVFALFSIALAAAEAAIGFAILMA 80

                         90
                 ....*....|....*...
gi 890833968  92 VYRNTQSVDINVLNRLKW 109
Cdd:NF040614  81 IYRMRDTINLDNINILRW 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
15-109 4.20e-26

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 93.01  E-value: 4.20e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968   15 HYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVMVYR 94
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYR 80

                          90
                  ....*....|....*
gi 890833968   95 NTQSVDINVLNRLKW 109
Cdd:pfam00420  81 THGTDDVDSLNLLKG 95
ndhE CHL00015
NADH dehydrogenase subunit 4L
 13-109 1.02e-24

NADH dehydrogenase subunit 4L


Pssm-ID: 176958  Cd Length: 101  Bit Score: 89.68  E-value: 1.02e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  13 LNHYIWLSAIIFTIGVIGVLTRRNAIVIFMSVELMLNAVNLLLTAFS--VHNNDPSGQVFVFFIMALAAAEVAVGLSIIV 90
Cdd:CHL00015   3 LEHVLILSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSdfFDSRQLKGDIFSIFVIAIAAAEAAIGLAIVS 82

                         90
                 ....*....|....*....
gi 890833968  91 MVYRNTQSVDINVLNRLKW 109
Cdd:CHL00015  83 SIYRNRKSTRINQSNLLKK 101
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 16-108 2.73e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 60.43  E-value: 2.73e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  16 YIWLSAIIFTIGVIG-VLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVMVYR 94
Cdd:MTH00180   5 YLTVGIILFILGVLGiVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVAYYR 84

                         90
                 ....*....|....
gi 890833968  95 NTQSVDINVLNRLK 108
Cdd:MTH00180  85 IRGTIAVKSLNLLR 98
ND4L MTH00001
NADH dehydrogenase subunit 4L; Provisional
 16-108 1.02e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177099  Cd Length: 99  Bit Score: 53.91  E-value: 1.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  16 YIWLSAIIFTIGVIG-VLTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVMVYR 94
Cdd:MTH00001   5 YLILVVILFLLGIWGiILNRGHFIIMLVSIELVLLSTFFLFLINSIEIDLLIEQIFTIMGLTIAAAESAIGLAIMVAYYR 84

                         90
                 ....*....|....
gi 890833968  95 NTQSVDINVLNRLK 108
Cdd:MTH00001  85 IRGTISLKSLNSLR 98
ND4L MTH00192
NADH dehydrogenase subunit 4L; Provisional
 16-108 4.26e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177240  Cd Length: 99  Bit Score: 47.22  E-value: 4.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  16 YIWLSAIIFTIGVIGVLTRRNAIV-IFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVMVYR 94
Cdd:MTH00192   5 YLLVSIILFTTGVSGIIINKNNIIlILMSIELILLAISYLLIVYSVTLDNLLGIIFSLMVLTVAAAESAIGLAILVAYFR 84

                         90
                 ....*....|....
gi 890833968  95 NTQSVDINVLNRLK 108
Cdd:MTH00192  85 LTGTITIKALNLLR 98
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 22-108 2.76e-04

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 36.82  E-value: 2.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  22 IIFTIGVIGVLTRRNAIV-IFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVMVYRNTQSVD 100
Cdd:MTH00043  10 SSFFLGLLGILINRLHLLsILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVLLSRNHNSDL 89


                 ....*...
gi 890833968 101 INVLNRLK 108
Cdd:MTH00043  90 VASLNLLQ 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 21-107 2.58e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 34.15  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 890833968  21 AIIFTIGVIGV-LTRRNAIVIFMSVELMLNAVNLLLTAFSVHNNDPSGQVFVFFIMALAAAEVAVGLSIIVMVYRNTQSV 99
Cdd:MTH00181   6 ISAFILLLLGLsLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSD 85


                 ....*...
gi 890833968 100 DINVLNRL 107
Cdd:MTH00181  86 HLLKFNLL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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